931089:CDES RS04420
gene id: 931089:CDES_RS04420
uniprot id: A0A0M3Q9B6
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS03850
gene id: 931089:CDES_RS03850
uniprot id: A0A0M4CW03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

931089:CDES RS05415
gene id: 931089:CDES_RS05415
uniprot id: A0A0M5IIH8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

931089:CDES RS03455
gene id: 931089:CDES_RS03455
uniprot id: A0A0M4CWJ9
names: Similarity
messages: Belongs to the AccD/PCCB family.

931089:CDES RS06445
gene id: 931089:CDES_RS06445
uniprot id: A0A0M3Q9I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

931089:CDES RS02720
gene id: 931089:CDES_RS02720
uniprot id: A0A0M4CH17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

931089:CDES RS07000
gene id: 931089:CDES_RS07000
uniprot id: A0A0M4CQ13
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

931089:CDES RS10290
gene id: 931089:CDES_RS10290
uniprot id: A0A0M4CEW6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

931089:CDES RS00330
gene id: 931089:CDES_RS00330
uniprot id: A0A0M4CBW9
names: Subcellular Location Annotation
messages: Cytoplasm

931089:CDES RS07045
gene id: 931089:CDES_RS07045
uniprot id: A0A0M4CJF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

931089:CDES RS10925
gene id: 931089:CDES_RS10925
uniprot id: A0A0M5IJB5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

931089:CDES RS07925
gene id: 931089:CDES_RS07925
uniprot id: A0A0M4CGF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

931089:CDES RS08810
gene id: 931089:CDES_RS08810
uniprot id: A0A0M4CMG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

931089:CDES RS04220
gene id: 931089:CDES_RS04220
uniprot id: A0A0M5IP18
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

931089:CDES RS10235
gene id: 931089:CDES_RS10235
uniprot id: A0A0M4CR25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

931089:CDES RS02705
gene id: 931089:CDES_RS02705
uniprot id: A0A0M5IFT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

931089:CDES RS09355
gene id: 931089:CDES_RS09355
uniprot id: A0A0M4CQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

931089:CDES RS06170
gene id: 931089:CDES_RS06170
uniprot id: A0A0M4CPN9
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

931089:CDES RS03230
gene id: 931089:CDES_RS03230
uniprot id: A0A0M3Q968
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

931089:CDES RS05705
gene id: 931089:CDES_RS05705
uniprot id: A0A0M4CPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

931089:CDES RS08010
gene id: 931089:CDES_RS08010
uniprot id: A0A0M3Q9P6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

931089:CDES RS04000
gene id: 931089:CDES_RS04000
uniprot id: A0A0M4CIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

931089:CDES RS10555
gene id: 931089:CDES_RS10555
uniprot id: A0A0M3Q9Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

931089:CDES RS04215
gene id: 931089:CDES_RS04215
uniprot id: A0A0M4CNY8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

931089:CDES RS01185
gene id: 931089:CDES_RS01185
uniprot id: A0A0M3Q8X8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

931089:CDES RS11600
gene id: 931089:CDES_RS11600
uniprot id: A0A0M3QA26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

931089:CDES RS10560
gene id: 931089:CDES_RS10560
uniprot id: A0A0M4CZB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

931089:CDES RS01280
gene id: 931089:CDES_RS01280
uniprot id: A0A0M4CGM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

931089:CDES RS10430
gene id: 931089:CDES_RS10430
uniprot id: A0A0M5IUE4
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS10130
gene id: 931089:CDES_RS10130
uniprot id: A0A0M4CJF9
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS12765
gene id: 931089:CDES_RS12765
uniprot id: A0A0M3QA74
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

931089:CDES RS13485
gene id: 931089:CDES_RS13485
uniprot id: A0A0M4CLQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

931089:CDES RS02765
gene id: 931089:CDES_RS02765
uniprot id: A0A0M4CNB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

931089:CDES RS09620
gene id: 931089:CDES_RS09620
uniprot id: A0A0M5IJ78
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

931089:CDES RS13225
gene id: 931089:CDES_RS13225
uniprot id: A0A0M4CZN8
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

931089:CDES RS02730
gene id: 931089:CDES_RS02730
uniprot id: A0A0M3Q950
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

931089:CDES RS02820
gene id: 931089:CDES_RS02820
uniprot id: A0A0M4CEL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

931089:CDES RS06995
gene id: 931089:CDES_RS06995
uniprot id: A0A0M4CDX8
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

931089:CDES RS10775
gene id: 931089:CDES_RS10775
uniprot id: A0A0M4CJN8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

931089:CDES RS05825
gene id: 931089:CDES_RS05825
uniprot id: A0A0M4CPJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS03820
gene id: 931089:CDES_RS03820
uniprot id: A0A0M5IU12
names: Similarity
messages: Belongs to the peptidase S16 family.

931089:CDES RS09970
gene id: 931089:CDES_RS09970
uniprot id: A0A0M4CKG5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

931089:CDES RS04225
gene id: 931089:CDES_RS04225
uniprot id: A0A0M3Q9A8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

931089:CDES RS04480
gene id: 931089:CDES_RS04480
uniprot id: A0A0M4CHK9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

931089:CDES RS06305
gene id: 931089:CDES_RS06305
uniprot id: A0A0M5IU18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

931089:CDES RS00025
gene id: 931089:CDES_RS00025
uniprot id: A0A0M3Q8T4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

931089:CDES RS07095
gene id: 931089:CDES_RS07095
uniprot id: A0A0M4CIG6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

931089:CDES RS01435
gene id: 931089:CDES_RS01435
uniprot id: A0A0M4CHL2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

931089:CDES RS02675
gene id: 931089:CDES_RS02675
uniprot id: A0A0M4CKB6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

931089:CDES RS01590
gene id: 931089:CDES_RS01590
uniprot id: A0A0M5ITM6
names: Subcellular Location Annotation
messages: Cytoplasm

931089:CDES RS05545
gene id: 931089:CDES_RS05545
uniprot id: A0A0M4CLC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

931089:CDES RS10115
gene id: 931089:CDES_RS10115
uniprot id: A0A0M5IUD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

931089:CDES RS12955
gene id: 931089:CDES_RS12955
uniprot id: A0A0M4CKF4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

931089:CDES RS07515
gene id: 931089:CDES_RS07515
uniprot id: A0A0M4CIL3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

931089:CDES RS00300
gene id: 931089:CDES_RS00300
uniprot id: A0A0M5IFK1
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS09700
gene id: 931089:CDES_RS09700
uniprot id: A0A0M4CH26
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

931089:CDES RS03345
gene id: 931089:CDES_RS03345
uniprot id: A0A0M4CKK2
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS11970
gene id: 931089:CDES_RS11970
uniprot id: A0A0M4CRP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

931089:CDES RS01125
gene id: 931089:CDES_RS01125
uniprot id: A0A0M4CGK9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

931089:CDES RS02790
gene id: 931089:CDES_RS02790
uniprot id: A0A0M4CH24
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

931089:CDES RS05810
gene id: 931089:CDES_RS05810
uniprot id: A0A0M3Q9G4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

931089:CDES RS03735
gene id: 931089:CDES_RS03735
uniprot id: A0A0M4CEX6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

931089:CDES RS00005
gene id: 931089:CDES_RS00005
uniprot id: A0A0M5ITP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

931089:CDES RS11740
gene id: 931089:CDES_RS11740
uniprot id: A0A0M4CZ36
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

931089:CDES RS06425
gene id: 931089:CDES_RS06425
uniprot id: A0A0M4CPU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

931089:CDES RS10050
gene id: 931089:CDES_RS10050
uniprot id: A0A0M4CR01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

931089:CDES RS13580
gene id: 931089:CDES_RS13580
uniprot id: A0A0M4CKM5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

931089:CDES RS06380
gene id: 931089:CDES_RS06380
uniprot id: A0A0M4CI84
names: Similarity
messages: Belongs to the universal stress protein A family.

931089:CDES RS00155
gene id: 931089:CDES_RS00155
uniprot id: A0A0M4CVA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

931089:CDES RS10690
gene id: 931089:CDES_RS10690
uniprot id: A0A0M4CZD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

931089:CDES RS10395
gene id: 931089:CDES_RS10395
uniprot id: A0A0M4CYK7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

931089:CDES RS11580
gene id: 931089:CDES_RS11580
uniprot id: A0A0M4CRJ4
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

931089:CDES RS11855
gene id: 931089:CDES_RS11855
uniprot id: A0A0M4CK16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

931089:CDES RS13145
gene id: 931089:CDES_RS13145
uniprot id: A0A0M4CKH6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

931089:CDES RS04270
gene id: 931089:CDES_RS04270
uniprot id: A0A0M3Q9B0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

931089:CDES RS08410
gene id: 931089:CDES_RS08410
uniprot id: A0A0M4CGL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

931089:CDES RS09670
gene id: 931089:CDES_RS09670
uniprot id: A0A0M4CMR8
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

931089:CDES RS08200
gene id: 931089:CDES_RS08200
uniprot id: A0A0M4CXQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

931089:CDES RS02985
gene id: 931089:CDES_RS02985
uniprot id: A0A0M5IIM5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

931089:CDES RS01310
gene id: 931089:CDES_RS01310
uniprot id: A0A0M3Q8Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

931089:CDES RS00210
gene id: 931089:CDES_RS00210
uniprot id: A0A0M4CMG2
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS04005
gene id: 931089:CDES_RS04005
uniprot id: A0A0M4CF07
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

931089:CDES RS09655
gene id: 931089:CDES_RS09655
uniprot id: A0A0M5IGE2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

931089:CDES RS02105
gene id: 931089:CDES_RS02105
uniprot id: A0A0M4CHT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

931089:CDES RS02460
gene id: 931089:CDES_RS02460
uniprot id: A0A0M5IL87
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

931089:CDES RS04720
gene id: 931089:CDES_RS04720
uniprot id: A0A0M4CHN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

931089:CDES RS11850
gene id: 931089:CDES_RS11850
uniprot id: A0A0M4CZT1
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS00180
gene id: 931089:CDES_RS00180
uniprot id: A0A0M4CUJ2
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS07955
gene id: 931089:CDES_RS07955
uniprot id: A0A0M4CIQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

931089:CDES RS03175
gene id: 931089:CDES_RS03175
uniprot id: A0A0M4CVQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

931089:CDES RS03340
gene id: 931089:CDES_RS03340
uniprot id: A0A0M4CH84
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS09320
gene id: 931089:CDES_RS09320
uniprot id: A0A0M3Q9X7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

931089:CDES RS02660
gene id: 931089:CDES_RS02660
uniprot id: A0A0M4CW83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

931089:CDES RS06780
gene id: 931089:CDES_RS06780
uniprot id: A0A0M3Q9L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

931089:CDES RS00920
gene id: 931089:CDES_RS00920
uniprot id: A0A0M4CMN6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

931089:CDES RS09115
gene id: 931089:CDES_RS09115
uniprot id: A0A0M4CJ30
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

931089:CDES RS08605
gene id: 931089:CDES_RS08605
uniprot id: A0A0M4CQI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

931089:CDES RS03390
gene id: 931089:CDES_RS03390
uniprot id: A0A0M5ILB1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

931089:CDES RS04290
gene id: 931089:CDES_RS04290
uniprot id: A0A0M3Q9A9
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS04640
gene id: 931089:CDES_RS04640
uniprot id: A0A0M4CP43
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

931089:CDES RS00830
gene id: 931089:CDES_RS00830
uniprot id: A0A0M3Q8W3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

931089:CDES RS09240
gene id: 931089:CDES_RS09240
uniprot id: A0A0M4CJ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

931089:CDES RS05715
gene id: 931089:CDES_RS05715
uniprot id: A0A0M3Q9G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

931089:CDES RS08560
gene id: 931089:CDES_RS08560
uniprot id: A0A0M4CYI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

931089:CDES RS07735
gene id: 931089:CDES_RS07735
uniprot id: A0A0M4CGD2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

931089:CDES RS05650
gene id: 931089:CDES_RS05650
uniprot id: A0A0M5ITZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

931089:CDES RS06955
gene id: 931089:CDES_RS06955
uniprot id: A0A0M4CIF1
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

931089:CDES RS00240
gene id: 931089:CDES_RS00240
uniprot id: A0A0M5IQK2
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

931089:CDES RS08700
gene id: 931089:CDES_RS08700
uniprot id: A0A0M3Q9S3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

931089:CDES RS04660
gene id: 931089:CDES_RS04660
uniprot id: A0A0M3Q9C4
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

931089:CDES RS06430
gene id: 931089:CDES_RS06430
uniprot id: A0A0M5IP80
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

931089:CDES RS04665
gene id: 931089:CDES_RS04665
uniprot id: A0A0M4CL09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS03835
gene id: 931089:CDES_RS03835
uniprot id: A0A0M4CKR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

931089:CDES RS03410
gene id: 931089:CDES_RS03410
uniprot id: A0A0M4CKK8
names: Similarity
messages: Belongs to the citrate synthase family.

931089:CDES RS04110
gene id: 931089:CDES_RS04110
uniprot id: A0A0M4CHG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

931089:CDES RS02630
gene id: 931089:CDES_RS02630
uniprot id: A0A0M4CHZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

931089:CDES RS01420
gene id: 931089:CDES_RS01420
uniprot id: A0A0M5IIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

931089:CDES RS05865
gene id: 931089:CDES_RS05865
uniprot id: A0A0M4CWU6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

931089:CDES RS08030
gene id: 931089:CDES_RS08030
uniprot id: A0A0M3Q9R9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931089:CDES RS12095
gene id: 931089:CDES_RS12095
uniprot id: A0A0M4CRQ6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

931089:CDES RS08975
gene id: 931089:CDES_RS08975
uniprot id: A0A0M4CYP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

931089:CDES RS05690
gene id: 931089:CDES_RS05690
uniprot id: A0A0M4CIY4
names: Similarity
messages: Belongs to the UPF0045 family.

931089:CDES RS10340
gene id: 931089:CDES_RS10340
uniprot id: A0A0M4CKL5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

931089:CDES RS00720
gene id: 931089:CDES_RS00720
uniprot id: A0A0M4CC06
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

931089:CDES RS06130
gene id: 931089:CDES_RS06130
uniprot id: A0A0M3Q9H3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

931089:CDES RS10680
gene id: 931089:CDES_RS10680
uniprot id: A0A0M3QA31
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

931089:CDES RS00425
gene id: 931089:CDES_RS00425
uniprot id: A0A0M4CGE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

931089:CDES RS01380
gene id: 931089:CDES_RS01380
uniprot id: A0A0M3Q902
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

931089:CDES RS10150
gene id: 931089:CDES_RS10150
uniprot id: A0A0M4CKJ1
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

931089:CDES RS08160
gene id: 931089:CDES_RS08160
uniprot id: A0A0M4CQD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

931089:CDES RS09955
gene id: 931089:CDES_RS09955
uniprot id: A0A0M5IJ89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

931089:CDES RS07830
gene id: 931089:CDES_RS07830
uniprot id: A0A0M4CIP5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

931089:CDES RS03360
gene id: 931089:CDES_RS03360
uniprot id: A0A0M4CVS9
names: Similarity
messages: Belongs to the peptidase C40 family.

931089:CDES RS09110
gene id: 931089:CDES_RS09110
uniprot id: A0A0M3Q9W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

931089:CDES RS01050
gene id: 931089:CDES_RS01050
uniprot id: A0A0M3Q8Z1
names: Similarity
messages: Belongs to the glutamate synthase family.

931089:CDES RS04965
gene id: 931089:CDES_RS04965
uniprot id: A0A0M5ILG1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

931089:CDES RS06115
gene id: 931089:CDES_RS06115
uniprot id: A0A0M4CI56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

931089:CDES RS12825
gene id: 931089:CDES_RS12825
uniprot id: A0A0M4CI74
names: Similarity
messages: Belongs to the universal stress protein A family.

931089:CDES RS10405
gene id: 931089:CDES_RS10405
uniprot id: A0A0M3Q9Y2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

931089:CDES RS12100
gene id: 931089:CDES_RS12100
uniprot id: A0A0M5IUJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

931089:CDES RS11350
gene id: 931089:CDES_RS11350
uniprot id: A0A0M4CYY6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

931089:CDES RS01760
gene id: 931089:CDES_RS01760
uniprot id: A0A0M4CMX9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

931089:CDES RS09930
gene id: 931089:CDES_RS09930
uniprot id: A0A0M3QA01
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS03115
gene id: 931089:CDES_RS03115
uniprot id: A0A0M4CVP5
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

931089:CDES RS02810
gene id: 931089:CDES_RS02810
uniprot id: A0A0M4CI18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

931089:CDES RS11390
gene id: 931089:CDES_RS11390
uniprot id: A0A0M4CZL7
names: Similarity
messages: Belongs to the GARS family.

931089:CDES RS08325
gene id: 931089:CDES_RS08325
uniprot id: A0A0M3Q9S8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

931089:CDES RS00065
gene id: 931089:CDES_RS00065
uniprot id: A0A0M5INQ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

931089:CDES RS01265
gene id: 931089:CDES_RS01265
uniprot id: A0A0M5ITL6
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS09405
gene id: 931089:CDES_RS09405
uniprot id: A0A0M4CEL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

931089:CDES RS04600
gene id: 931089:CDES_RS04600
uniprot id: A0A0M5ILT9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

931089:CDES RS01285
gene id: 931089:CDES_RS01285
uniprot id: A0A0M4CJV0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

931089:CDES RS05445
gene id: 931089:CDES_RS05445
uniprot id: A0A0M4CDG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

931089:CDES RS08190
gene id: 931089:CDES_RS08190
uniprot id: A0A0M5IR86
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

931089:CDES RS06610
gene id: 931089:CDES_RS06610
uniprot id: A0A0M4CFZ5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS02390
gene id: 931089:CDES_RS02390
uniprot id: A0A0M3Q930
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

931089:CDES RS13600
gene id: 931089:CDES_RS13600
uniprot id: A0A0M4CZT8
names: Similarity
messages: Belongs to the ParB family.

931089:CDES RS08850
gene id: 931089:CDES_RS08850
uniprot id: A0A0M3Q9S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

931089:CDES RS01330
gene id: 931089:CDES_RS01330
uniprot id: A0A0M3Q901
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

931089:CDES RS06480
gene id: 931089:CDES_RS06480
uniprot id: A0A0M4CDT1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

931089:CDES RS09575
gene id: 931089:CDES_RS09575
uniprot id: A0A0M4CH10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

931089:CDES RS08045
gene id: 931089:CDES_RS08045
uniprot id: A0A0M4CJS2
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

931089:CDES RS06830
gene id: 931089:CDES_RS06830
uniprot id: A0A0M3Q9M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

931089:CDES RS13375
gene id: 931089:CDES_RS13375
uniprot id: A0A0M4CFU7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

931089:CDES RS08790
gene id: 931089:CDES_RS08790
uniprot id: A0A0M4CQK4
names: Similarity
messages: Belongs to the UPF0102 family.

931089:CDES RS13085
gene id: 931089:CDES_RS13085
uniprot id: A0A0M4CNX9
names: Similarity
messages: Belongs to the FPG family.

931089:CDES RS05520
gene id: 931089:CDES_RS05520
uniprot id: A0A0M5IG18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

931089:CDES RS04035
gene id: 931089:CDES_RS04035
uniprot id: A0A0M3Q999
names: Similarity
messages: Belongs to the AccD/PCCB family.

931089:CDES RS11430
gene id: 931089:CDES_RS11430
uniprot id: A0A0M4CF87
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS01635
gene id: 931089:CDES_RS01635
uniprot id: A0A0M4CHN3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

931089:CDES RS11605
gene id: 931089:CDES_RS11605
uniprot id: A0A0M4CNE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

931089:CDES RS05120
gene id: 931089:CDES_RS05120
uniprot id: A0A0M3Q9D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

931089:CDES RS11660
gene id: 931089:CDES_RS11660
uniprot id: A0A0M4CJZ5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

931089:CDES RS09760
gene id: 931089:CDES_RS09760
uniprot id: A0A0M4CKE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

931089:CDES RS01735
gene id: 931089:CDES_RS01735
uniprot id: A0A0M4CV34
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

931089:CDES RS08590
gene id: 931089:CDES_RS08590
uniprot id: A0A0M4CGN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

931089:CDES RS05630
gene id: 931089:CDES_RS05630
uniprot id: A0A0M4CFM3
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS09375
gene id: 931089:CDES_RS09375
uniprot id: A0A0M4CJ63
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

931089:CDES RS05425
gene id: 931089:CDES_RS05425
uniprot id: A0A0M3Q9G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

931089:CDES RS11900
gene id: 931089:CDES_RS11900
uniprot id: A0A0M4CFD8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

931089:CDES RS06240
gene id: 931089:CDES_RS06240
uniprot id: A0A0M3Q9H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

931089:CDES RS09580
gene id: 931089:CDES_RS09580
uniprot id: A0A0M4CEP0
names: Similarity
messages: Belongs to the asparagine synthetase family.

931089:CDES RS01430
gene id: 931089:CDES_RS01430
uniprot id: A0A0M3Q904
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS01230
gene id: 931089:CDES_RS01230
uniprot id: A0A0M4CHJ3
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS01950
gene id: 931089:CDES_RS01950
uniprot id: A0A0M4CVY6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

931089:CDES RS05360
gene id: 931089:CDES_RS05360
uniprot id: A0A0M3Q9E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

931089:CDES RS12960
gene id: 931089:CDES_RS12960
uniprot id: A0A0M4CNW5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS01425
gene id: 931089:CDES_RS01425
uniprot id: A0A0M4CUZ0
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS01155
gene id: 931089:CDES_RS01155
uniprot id: A0A0M3Q8Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

931089:CDES RS00450
gene id: 931089:CDES_RS00450
uniprot id: A0A0M4CHC5
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS02750
gene id: 931089:CDES_RS02750
uniprot id: A0A0M4CEK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

931089:CDES RS05615
gene id: 931089:CDES_RS05615
uniprot id: A0A0M3Q9F9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

931089:CDES RS02590
gene id: 931089:CDES_RS02590
uniprot id: A0A0M3Q945
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS03840
gene id: 931089:CDES_RS03840
uniprot id: A0A0M5IID0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

931089:CDES RS09965
gene id: 931089:CDES_RS09965
uniprot id: A0A0M4CYE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

931089:CDES RS02900
gene id: 931089:CDES_RS02900
uniprot id: A0A0M5ITY0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

931089:CDES RS06150
gene id: 931089:CDES_RS06150
uniprot id: A0A0M4CJ47
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

931089:CDES RS00980
gene id: 931089:CDES_RS00980
uniprot id: A0A0M3Q8X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

931089:CDES RS00535
gene id: 931089:CDES_RS00535
uniprot id: A0A0M4CBY4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

931089:CDES RS11495
gene id: 931089:CDES_RS11495
uniprot id: A0A0M3QA22
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

931089:CDES RS06985
gene id: 931089:CDES_RS06985
uniprot id: A0A0M4CJE2
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS00670
gene id: 931089:CDES_RS00670
uniprot id: A0A0M5ITR8
names: Similarity
messages: Belongs to the peptidase M20A family.

931089:CDES RS01070
gene id: 931089:CDES_RS01070
uniprot id: A0A0M4CJT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

931089:CDES RS05580
gene id: 931089:CDES_RS05580
uniprot id: A0A0M4CPG3
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS05660
gene id: 931089:CDES_RS05660
uniprot id: A0A0M4CHZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

931089:CDES RS05155
gene id: 931089:CDES_RS05155
uniprot id: A0A0M4CX86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

931089:CDES RS09055
gene id: 931089:CDES_RS09055
uniprot id: A0A0M4CMJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

931089:CDES RS02120
gene id: 931089:CDES_RS02120
uniprot id: A0A0M4CCF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

931089:CDES RS12035
gene id: 931089:CDES_RS12035
uniprot id: A0A0M3QA79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

931089:CDES RS08650
gene id: 931089:CDES_RS08650
uniprot id: A0A0M3Q9S0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

931089:CDES RS11085
gene id: 931089:CDES_RS11085
uniprot id: A0A0M4CHK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931089:CDES RS02455
gene id: 931089:CDES_RS02455
uniprot id: A0A0M4CN70
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

931089:CDES RS05960
gene id: 931089:CDES_RS05960
uniprot id: A0A0M3Q9G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

931089:CDES RS05305
gene id: 931089:CDES_RS05305
uniprot id: A0A0M4CIU2
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS07630
gene id: 931089:CDES_RS07630
uniprot id: A0A0M5IUC3
names: Caution
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS03725
gene id: 931089:CDES_RS03725
uniprot id: A0A0M4CVY3
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

931089:CDES RS06950
gene id: 931089:CDES_RS06950
uniprot id: A0A0M4CXY1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

931089:CDES RS02940
gene id: 931089:CDES_RS02940
uniprot id: A0A0M4CI30
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

931089:CDES RS03910
gene id: 931089:CDES_RS03910
uniprot id: A0A0M4CKR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

931089:CDES RS13620
gene id: 931089:CDES_RS13620
uniprot id: A0A0M5IM66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

931089:CDES RS03745
gene id: 931089:CDES_RS03745
uniprot id: A0A0M3Q990
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

931089:CDES RS08235
gene id: 931089:CDES_RS08235
uniprot id: A0A0M5IU75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

931089:CDES RS01030
gene id: 931089:CDES_RS01030
uniprot id: A0A0M3Q8X2
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS05840
gene id: 931089:CDES_RS05840
uniprot id: A0A0M4CXI6
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS09865
gene id: 931089:CDES_RS09865
uniprot id: A0A0M5IUJ1
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

931089:CDES RS11525
gene id: 931089:CDES_RS11525
uniprot id: A0A0M4CZN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

931089:CDES RS00420
gene id: 931089:CDES_RS00420
uniprot id: A0A0M4CVC0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

931089:CDES RS06250
gene id: 931089:CDES_RS06250
uniprot id: A0A0M4CI72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

931089:CDES RS06515
gene id: 931089:CDES_RS06515
uniprot id: A0A0M3Q9K8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

931089:CDES RS06235
gene id: 931089:CDES_RS06235
uniprot id: A0A0M5ILJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

931089:CDES RS13455
gene id: 931089:CDES_RS13455
uniprot id: A0A0M4D0F7
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

931089:CDES RS12705
gene id: 931089:CDES_RS12705
uniprot id: A0A0M4CFN2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

931089:CDES RS02755
gene id: 931089:CDES_RS02755
uniprot id: A0A0M4CCM1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

931089:CDES RS09595
gene id: 931089:CDES_RS09595
uniprot id: A0A0M5IPH4
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

931089:CDES RS11425
gene id: 931089:CDES_RS11425
uniprot id: A0A0M4CHP7
names: Similarity
messages: Belongs to the TPP enzyme family.

931089:CDES RS02665
gene id: 931089:CDES_RS02665
uniprot id: A0A0M4CH09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

931089:CDES RS09510
gene id: 931089:CDES_RS09510
uniprot id: A0A0M4CY91
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

931089:CDES RS06450
gene id: 931089:CDES_RS06450
uniprot id: A0A0M4CLN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

931089:CDES RS10040
gene id: 931089:CDES_RS10040
uniprot id: A0A0M4CH64
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

931089:CDES RS05540
gene id: 931089:CDES_RS05540
uniprot id: A0A0M4CHX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

931089:CDES RS03690
gene id: 931089:CDES_RS03690
uniprot id: A0A0M5ILC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

931089:CDES RS01340
gene id: 931089:CDES_RS01340
uniprot id: A0A0M4CVN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

931089:CDES RS06880
gene id: 931089:CDES_RS06880
uniprot id: A0A0M3Q9M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

931089:CDES RS09945
gene id: 931089:CDES_RS09945
uniprot id: A0A0M4CJD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

931089:CDES RS11550
gene id: 931089:CDES_RS11550
uniprot id: A0A0M3QA24
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS01065
gene id: 931089:CDES_RS01065
uniprot id: A0A0M4CGK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

931089:CDES RS06475
gene id: 931089:CDES_RS06475
uniprot id: A0A0M4CFY0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

931089:CDES RS03890
gene id: 931089:CDES_RS03890
uniprot id: A0A0M4CWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

931089:CDES RS10175
gene id: 931089:CDES_RS10175
uniprot id: A0A0M3QA11
names: Cofactor
messages: Can also use Mn(2+) ion.

931089:CDES RS02310
gene id: 931089:CDES_RS02310
uniprot id: A0A0M3Q938
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS08705
gene id: 931089:CDES_RS08705
uniprot id: A0A0M4CXX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

931089:CDES RS11145
gene id: 931089:CDES_RS11145
uniprot id: A0A0M4CYV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS03510
gene id: 931089:CDES_RS03510
uniprot id: A0A0M4CWK6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

931089:CDES RS04205
gene id: 931089:CDES_RS04205
uniprot id: A0A0M4CF35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

931089:CDES RS10945
gene id: 931089:CDES_RS10945
uniprot id: A0A0M4CHI9
names: Similarity
messages: Belongs to the peptidase S58 family.

931089:CDES RS12105
gene id: 931089:CDES_RS12105
uniprot id: A0A0M4CZW4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

931089:CDES RS00345
gene id: 931089:CDES_RS00345
uniprot id: A0A0M4CVB2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS11800
gene id: 931089:CDES_RS11800
uniprot id: A0A0M5IGI9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

931089:CDES RS05210
gene id: 931089:CDES_RS05210
uniprot id: A0A0M3Q9E2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS02635
gene id: 931089:CDES_RS02635
uniprot id: A0A0M4CEI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

931089:CDES RS03880
gene id: 931089:CDES_RS03880
uniprot id: A0A0M4CNU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

931089:CDES RS00015
gene id: 931089:CDES_RS00015
uniprot id: A0A0M4CJG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

931089:CDES RS11755
gene id: 931089:CDES_RS11755
uniprot id: A0A0M4CHT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

931089:CDES RS02835
gene id: 931089:CDES_RS02835
uniprot id: A0A0M3Q954
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS11035
gene id: 931089:CDES_RS11035
uniprot id: A0A0M4CZH8
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

931089:CDES RS05925
gene id: 931089:CDES_RS05925
uniprot id: A0A0M4CWV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

931089:CDES RS01985
gene id: 931089:CDES_RS01985
uniprot id: A0A0M4CEB0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

931089:CDES RS07635
gene id: 931089:CDES_RS07635
uniprot id: A0A0M4CY74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

931089:CDES RS01770
gene id: 931089:CDES_RS01770
uniprot id: A0A0M4CVU7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

931089:CDES RS04325
gene id: 931089:CDES_RS04325
uniprot id: A0A0M4CF51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

931089:CDES RS02565
gene id: 931089:CDES_RS02565
uniprot id: A0A0M4CHY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

931089:CDES RS05300
gene id: 931089:CDES_RS05300
uniprot id: A0A0M4CWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

931089:CDES RS10915
gene id: 931089:CDES_RS10915
uniprot id: A0A0M4CJQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

931089:CDES RS06685
gene id: 931089:CDES_RS06685
uniprot id: A0A0M4CPX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

931089:CDES RS08165
gene id: 931089:CDES_RS08165
uniprot id: A0A0M3Q9S2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

931089:CDES RS04185
gene id: 931089:CDES_RS04185
uniprot id: A0A0M5IID9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

931089:CDES RS08405
gene id: 931089:CDES_RS08405
uniprot id: A0A0M3Q9R0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

931089:CDES RS10320
gene id: 931089:CDES_RS10320
uniprot id: A0A0M4CN05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

931089:CDES RS05100
gene id: 931089:CDES_RS05100
uniprot id: A0A0M4CX77
names: Similarity
messages: Belongs to the ArsC family.

931089:CDES RS02555
gene id: 931089:CDES_RS02555
uniprot id: A0A0M5IFS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

931089:CDES RS11840
gene id: 931089:CDES_RS11840
uniprot id: A0A0M4CRM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

931089:CDES RS02670
gene id: 931089:CDES_RS02670
uniprot id: A0A0M3Q942
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

931089:CDES RS11260
gene id: 931089:CDES_RS11260
uniprot id: A0A0M3QA50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

931089:CDES RS05745
gene id: 931089:CDES_RS05745
uniprot id: A0A0M4CWS9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

931089:CDES RS10660
gene id: 931089:CDES_RS10660
uniprot id: A0A0M3Q9Z2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

931089:CDES RS03885
gene id: 931089:CDES_RS03885
uniprot id: A0A0M5IP08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

931089:CDES RS09645
gene id: 931089:CDES_RS09645
uniprot id: A0A0M4CEP6
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS09070
gene id: 931089:CDES_RS09070
uniprot id: A0A0M4CY32
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS04345
gene id: 931089:CDES_RS04345
uniprot id: A0A0M5ILE2
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

931089:CDES RS02450
gene id: 931089:CDES_RS02450
uniprot id: A0A0M4CCJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

931089:CDES RS11090
gene id: 931089:CDES_RS11090
uniprot id: A0A0M4CF49
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

931089:CDES RS09980
gene id: 931089:CDES_RS09980
uniprot id: A0A0M3QA03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

931089:CDES RS10850
gene id: 931089:CDES_RS10850
uniprot id: A0A0M4CJP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

931089:CDES RS09940
gene id: 931089:CDES_RS09940
uniprot id: A0A0M4CZ26
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

931089:CDES RS00700
gene id: 931089:CDES_RS00700
uniprot id: A0A0M5II38
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS12215
gene id: 931089:CDES_RS12215
uniprot id: A0A0M4CHZ2
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS07690
gene id: 931089:CDES_RS07690
uniprot id: A0A0M5IPB6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS08595
gene id: 931089:CDES_RS08595
uniprot id: A0A0M4CED8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

931089:CDES RS11020
gene id: 931089:CDES_RS11020
uniprot id: A0A0M4CF42
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

931089:CDES RS03600
gene id: 931089:CDES_RS03600
uniprot id: A0A0M3Q984
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

931089:CDES RS01320
gene id: 931089:CDES_RS01320
uniprot id: A0A0M4CC67
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

931089:CDES RS12155
gene id: 931089:CDES_RS12155
uniprot id: A0A0M4CHY3
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

931089:CDES RS09605
gene id: 931089:CDES_RS09605
uniprot id: A0A0M3Q9Y9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

931089:CDES RS08470
gene id: 931089:CDES_RS08470
uniprot id: A0A0M4CGM1
names: Similarity
messages: Belongs to the YciI family.

931089:CDES RS02305
gene id: 931089:CDES_RS02305
uniprot id: A0A0M4CN52
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS02190
gene id: 931089:CDES_RS02190
uniprot id: A0A0M3Q920
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

931089:CDES RS11670
gene id: 931089:CDES_RS11670
uniprot id: A0A0M3QA65
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

931089:CDES RS10110
gene id: 931089:CDES_RS10110
uniprot id: A0A0M4CR09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

931089:CDES RS03185
gene id: 931089:CDES_RS03185
uniprot id: A0A0M4CI55
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-73 and Arg-76) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

931089:CDES RS02055
gene id: 931089:CDES_RS02055
uniprot id: A0A0M4CCE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

931089:CDES RS05595
gene id: 931089:CDES_RS05595
uniprot id: A0A0M4CXE8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

931089:CDES RS04165
gene id: 931089:CDES_RS04165
uniprot id: A0A0M4CWU4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

931089:CDES RS08515
gene id: 931089:CDES_RS08515
uniprot id: A0A0M5IR96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

931089:CDES RS02760
gene id: 931089:CDES_RS02760
uniprot id: A0A0M3Q946
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

931089:CDES RS05560
gene id: 931089:CDES_RS05560
uniprot id: A0A0M4CIW8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

931089:CDES RS04105
gene id: 931089:CDES_RS04105
uniprot id: A0A0M4CWT6
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

931089:CDES RS07725
gene id: 931089:CDES_RS07725
uniprot id: A0A0M3Q9Q7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

931089:CDES RS10770
gene id: 931089:CDES_RS10770
uniprot id: A0A0M4CZE3
names: Similarity
messages: Belongs to the hyi family.

931089:CDES RS05310
gene id: 931089:CDES_RS05310
uniprot id: A0A0M3Q9E6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

931089:CDES RS13865
gene id: 931089:CDES_RS13865
uniprot id: A0A0M3QAB6
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

931089:CDES RS10565
gene id: 931089:CDES_RS10565
uniprot id: A0A0M4CJL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

931089:CDES RS05060
gene id: 931089:CDES_RS05060
uniprot id: A0A0M4CWH7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

931089:CDES RS11545
gene id: 931089:CDES_RS11545
uniprot id: A0A0M5IJ11
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

931089:CDES RS11440
gene id: 931089:CDES_RS11440
uniprot id: A0A0M4CRI2
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS09265
gene id: 931089:CDES_RS09265
uniprot id: A0A0M4CY58
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS04385
gene id: 931089:CDES_RS04385
uniprot id: A0A0M4CF59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

931089:CDES RS08370
gene id: 931089:CDES_RS08370
uniprot id: A0A0M4CYG3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

931089:CDES RS11860
gene id: 931089:CDES_RS11860
uniprot id: A0A0M3QA36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

931089:CDES RS10700
gene id: 931089:CDES_RS10700
uniprot id: A0A0M4CN54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

931089:CDES RS00710
gene id: 931089:CDES_RS00710
uniprot id: A0A0M4CHF0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

931089:CDES RS05795
gene id: 931089:CDES_RS05795
uniprot id: A0A0M5IIV9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

931089:CDES RS10490
gene id: 931089:CDES_RS10490
uniprot id: A0A0M5IUL1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

931089:CDES RS05500
gene id: 931089:CDES_RS05500
uniprot id: A0A0M4CFK8
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS04025
gene id: 931089:CDES_RS04025
uniprot id: A0A0M5ILD3
names: Similarity
messages: Belongs to the citrate synthase family.

931089:CDES RS07685
gene id: 931089:CDES_RS07685
uniprot id: A0A0M4CQ87
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS11975
gene id: 931089:CDES_RS11975
uniprot id: A0A0M5IGL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

931089:CDES RS09200
gene id: 931089:CDES_RS09200
uniprot id: A0A0M4CY51
names: Similarity
messages: Belongs to the HSP15 family.

931089:CDES RS03235
gene id: 931089:CDES_RS03235
uniprot id: A0A0M5IIB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

931089:CDES RS11560
gene id: 931089:CDES_RS11560
uniprot id: A0A0M4CL15
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS06805
gene id: 931089:CDES_RS06805
uniprot id: A0A0M4CDW0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

931089:CDES RS02505
gene id: 931089:CDES_RS02505
uniprot id: A0A0M4CEH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

931089:CDES RS03920
gene id: 931089:CDES_RS03920
uniprot id: A0A0M4CW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

931089:CDES RS02745
gene id: 931089:CDES_RS02745
uniprot id: A0A0M4CI10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

931089:CDES RS11650
gene id: 931089:CDES_RS11650
uniprot id: A0A0M3QA28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

931089:CDES RS11340
gene id: 931089:CDES_RS11340
uniprot id: A0A0M4CNB1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

931089:CDES RS05885
gene id: 931089:CDES_RS05885
uniprot id: A0A0M4CDL8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

931089:CDES RS03125
gene id: 931089:CDES_RS03125
uniprot id: A0A0M4CEQ2
names: Similarity
messages: Belongs to the DNA photolyase family.

931089:CDES RS11950
gene id: 931089:CDES_RS11950
uniprot id: A0A0M4CL64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

931089:CDES RS10540
gene id: 931089:CDES_RS10540
uniprot id: A0A0M4CEZ5
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS12350
gene id: 931089:CDES_RS12350
uniprot id: A0A0M4CZZ8
names: Similarity
messages: Belongs to the universal stress protein A family.

931089:CDES RS07625
gene id: 931089:CDES_RS07625
uniprot id: A0A0M3Q9Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

931089:CDES RS01755
gene id: 931089:CDES_RS01755
uniprot id: A0A0M3Q900
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS11770
gene id: 931089:CDES_RS11770
uniprot id: A0A0M3QA68
names: Similarity
messages: Belongs to the peptidase S13 family.

931089:CDES RS05220
gene id: 931089:CDES_RS05220
uniprot id: A0A0M4CHU1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

931089:CDES RS06520
gene id: 931089:CDES_RS06520
uniprot id: A0A0M5ILZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

931089:CDES RS01275
gene id: 931089:CDES_RS01275
uniprot id: A0A0M3Q8Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

931089:CDES RS11080
gene id: 931089:CDES_RS11080
uniprot id: A0A0M4CKV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931089:CDES RS05670
gene id: 931089:CDES_RS05670
uniprot id: A0A0M4CLE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

931089:CDES RS07120
gene id: 931089:CDES_RS07120
uniprot id: A0A0M3Q9L1
names: Similarity
messages: Belongs to the peptidase C40 family.

931089:CDES RS05905
gene id: 931089:CDES_RS05905
uniprot id: A0A0M4CI29
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS11875
gene id: 931089:CDES_RS11875
uniprot id: A0A0M4CZ50
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

931089:CDES RS06970
gene id: 931089:CDES_RS06970
uniprot id: A0A0M5IG55
names: Similarity
messages: Belongs to the peptidase M18 family.

931089:CDES RS01530
gene id: 931089:CDES_RS01530
uniprot id: A0A0M4CVR2
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS02655
gene id: 931089:CDES_RS02655
uniprot id: A0A0M5INX8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

931089:CDES RS07990
gene id: 931089:CDES_RS07990
uniprot id: A0A0M4CGG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

931089:CDES RS10520
gene id: 931089:CDES_RS10520
uniprot id: A0A0M4CYN0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

931089:CDES RS13305
gene id: 931089:CDES_RS13305
uniprot id: A0A0M4CFU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

931089:CDES RS11275
gene id: 931089:CDES_RS11275
uniprot id: A0A0M4CJU7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

931089:CDES RS05610
gene id: 931089:CDES_RS05610
uniprot id: A0A0M5IR05
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS00415
gene id: 931089:CDES_RS00415
uniprot id: A0A0M3Q8U8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

931089:CDES RS02205
gene id: 931089:CDES_RS02205
uniprot id: A0A0M4CK62
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS05675
gene id: 931089:CDES_RS05675
uniprot id: A0A0M5IG15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

931089:CDES RS09950
gene id: 931089:CDES_RS09950
uniprot id: A0A0M4CMV2
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS03925
gene id: 931089:CDES_RS03925
uniprot id: A0A0M3Q995
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

931089:CDES RS03640
gene id: 931089:CDES_RS03640
uniprot id: A0A0M4CWM0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

931089:CDES RS03845
gene id: 931089:CDES_RS03845
uniprot id: A0A0M3Q994
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

931089:CDES RS06815
gene id: 931089:CDES_RS06815
uniprot id: A0A0M4CPZ2
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS04455
gene id: 931089:CDES_RS04455
uniprot id: A0A0M4CD58
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS07970
gene id: 931089:CDES_RS07970
uniprot id: A0A0M5IIR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

931089:CDES RS02345
gene id: 931089:CDES_RS02345
uniprot id: A0A0M4CVE0
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS05140
gene id: 931089:CDES_RS05140
uniprot id: A0A0M3Q9E9
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

931089:CDES RS08960
gene id: 931089:CDES_RS08960
uniprot id: A0A0M4CEH7
names: Similarity
messages: Belongs to the acylphosphatase family.

931089:CDES RS00430
gene id: 931089:CDES_RS00430
uniprot id: A0A0M4CJL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

931089:CDES RS10165
gene id: 931089:CDES_RS10165
uniprot id: A0A0M4CEV4
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

931089:CDES RS04785
gene id: 931089:CDES_RS04785
uniprot id: A0A0M3Q9D5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

931089:CDES RS08935
gene id: 931089:CDES_RS08935
uniprot id: A0A0M3Q9T8
names: Similarity
messages: Belongs to the P(II) protein family.

931089:CDES RS07800
gene id: 931089:CDES_RS07800
uniprot id: A0A0M4CE59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

931089:CDES RS08745
gene id: 931089:CDES_RS08745
uniprot id: A0A0M4CIY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

931089:CDES RS12740
gene id: 931089:CDES_RS12740
uniprot id: A0A0M4CKD7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

931089:CDES RS10910
gene id: 931089:CDES_RS10910
uniprot id: A0A0M3QA38
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

931089:CDES RS02235
gene id: 931089:CDES_RS02235
uniprot id: A0A0M4CCG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

931089:CDES RS01525
gene id: 931089:CDES_RS01525
uniprot id: A0A0M5IL61
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

931089:CDES RS09495
gene id: 931089:CDES_RS09495
uniprot id: A0A0M3Q9V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

931089:CDES RS06300
gene id: 931089:CDES_RS06300
uniprot id: A0A0M4CPQ6
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS12950
gene id: 931089:CDES_RS12950
uniprot id: A0A0M4D085
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

931089:CDES RS12695
gene id: 931089:CDES_RS12695
uniprot id: A0A0M4CLG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

931089:CDES RS12975
gene id: 931089:CDES_RS12975
uniprot id: A0A0M4CZK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

931089:CDES RS04350
gene id: 931089:CDES_RS04350
uniprot id: A0A0M4CWX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

931089:CDES RS06590
gene id: 931089:CDES_RS06590
uniprot id: A0A0M5IR37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS11455
gene id: 931089:CDES_RS11455
uniprot id: A0A0M4CZM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

931089:CDES RS03630
gene id: 931089:CDES_RS03630
uniprot id: A0A0M4CNQ2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

931089:CDES RS05030
gene id: 931089:CDES_RS05030
uniprot id: A0A0M5ITX9
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS02885
gene id: 931089:CDES_RS02885
uniprot id: A0A0M3Q956
names: Similarity
messages: Belongs to the WXG100 family.

931089:CDES RS11710
gene id: 931089:CDES_RS11710
uniprot id: A0A0M5IM09
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

931089:CDES RS03565
gene id: 931089:CDES_RS03565
uniprot id: A0A0M3Q981
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

931089:CDES RS08330
gene id: 931089:CDES_RS08330
uniprot id: A0A0M5IIR9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

931089:CDES RS02365
gene id: 931089:CDES_RS02365
uniprot id: A0A0M4CCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

931089:CDES RS10285
gene id: 931089:CDES_RS10285
uniprot id: A0A0M4CH97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

931089:CDES RS08905
gene id: 931089:CDES_RS08905
uniprot id: A0A0M4CGS5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

931089:CDES RS12810
gene id: 931089:CDES_RS12810
uniprot id: A0A0M3QA76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

931089:CDES RS11890
gene id: 931089:CDES_RS11890
uniprot id: A0A0M4CL54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

931089:CDES RS08445
gene id: 931089:CDES_RS08445
uniprot id: A0A0M4CMB7
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS10415
gene id: 931089:CDES_RS10415
uniprot id: A0A0M4CEY0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

931089:CDES RS09435
gene id: 931089:CDES_RS09435
uniprot id: A0A0M4CMN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

931089:CDES RS07965
gene id: 931089:CDES_RS07965
uniprot id: A0A0M4CM65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

931089:CDES RS02935
gene id: 931089:CDES_RS02935
uniprot id: A0A0M3Q958
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

931089:CDES RS13675
gene id: 931089:CDES_RS13675
uniprot id: A0A0M5IUP4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS09400
gene id: 931089:CDES_RS09400
uniprot id: A0A0M4CGY7
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS05325
gene id: 931089:CDES_RS05325
uniprot id: A0A0M4CPD3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS10345
gene id: 931089:CDES_RS10345
uniprot id: A0A0M4CHA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

931089:CDES RS02830
gene id: 931089:CDES_RS02830
uniprot id: A0A0M4CNC3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

931089:CDES RS09420
gene id: 931089:CDES_RS09420
uniprot id: A0A0M5ILU5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS08270
gene id: 931089:CDES_RS08270
uniprot id: A0A0M3Q9S6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

931089:CDES RS13430
gene id: 931089:CDES_RS13430
uniprot id: A0A0M4CLP8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

931089:CDES RS02465
gene id: 931089:CDES_RS02465
uniprot id: A0A0M3Q932
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

931089:CDES RS10995
gene id: 931089:CDES_RS10995
uniprot id: A0A0M3QA04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

931089:CDES RS06710
gene id: 931089:CDES_RS06710
uniprot id: A0A0M3Q9J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

931089:CDES RS00850
gene id: 931089:CDES_RS00850
uniprot id: A0A0M3Q8Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

931089:CDES RS04680
gene id: 931089:CDES_RS04680
uniprot id: A0A0M3Q9D1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS13015
gene id: 931089:CDES_RS13015
uniprot id: A0A0M3QAB9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

931089:CDES RS00305
gene id: 931089:CDES_RS00305
uniprot id: A0A0M3Q8U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

931089:CDES RS09630
gene id: 931089:CDES_RS09630
uniprot id: A0A0M4CKC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

931089:CDES RS02960
gene id: 931089:CDES_RS02960
uniprot id: A0A0M5INY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

931089:CDES RS11005
gene id: 931089:CDES_RS11005
uniprot id: A0A0M4CKU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

931089:CDES RS03615
gene id: 931089:CDES_RS03615
uniprot id: A0A0M4CEW0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

931089:CDES RS03575
gene id: 931089:CDES_RS03575
uniprot id: A0A0M4CWL3
names: Similarity
messages: Belongs to the AHA1 family.

931089:CDES RS08955
gene id: 931089:CDES_RS08955
uniprot id: A0A0M3Q9W3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

931089:CDES RS06555
gene id: 931089:CDES_RS06555
uniprot id: A0A0M5ILL0
names: Similarity
messages: Belongs to the universal stress protein A family.

931089:CDES RS00930
gene id: 931089:CDES_RS00930
uniprot id: A0A0M3Q8W8
names: Similarity
messages: Belongs to the peptidase M13 family.

931089:CDES RS02980
gene id: 931089:CDES_RS02980
uniprot id: A0A0M4CKF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

931089:CDES RS07975
gene id: 931089:CDES_RS07975
uniprot id: A0A0M4CXN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

931089:CDES RS01680
gene id: 931089:CDES_RS01680
uniprot id: A0A0M4CJZ6
names: Similarity
messages: Belongs to the peptidase C56 family.

931089:CDES RS08300
gene id: 931089:CDES_RS08300
uniprot id: A0A0M5IUE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

931089:CDES RS10440
gene id: 931089:CDES_RS10440
uniprot id: A0A0M4CJJ9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

931089:CDES RS11540
gene id: 931089:CDES_RS11540
uniprot id: A0A0M4CND9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

931089:CDES RS05655
gene id: 931089:CDES_RS05655
uniprot id: A0A0M4CXF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

931089:CDES RS06195
gene id: 931089:CDES_RS06195
uniprot id: A0A0M4CLK4
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

931089:CDES RS03020
gene id: 931089:CDES_RS03020
uniprot id: A0A0M5IFU1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

931089:CDES RS03470
gene id: 931089:CDES_RS03470
uniprot id: A0A0M3Q977
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS11310
gene id: 931089:CDES_RS11310
uniprot id: A0A0M4CF75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

931089:CDES RS12165
gene id: 931089:CDES_RS12165
uniprot id: A0A0M4CRR4
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

931089:CDES RS01705
gene id: 931089:CDES_RS01705
uniprot id: A0A0M3Q8Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

931089:CDES RS10145
gene id: 931089:CDES_RS10145
uniprot id: A0A0M4CYH3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

931089:CDES RS01000
gene id: 931089:CDES_RS01000
uniprot id: A0A0M3Q8Y9
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

931089:CDES RS07615
gene id: 931089:CDES_RS07615
uniprot id: A0A0M4CE39
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

931089:CDES RS03080
gene id: 931089:CDES_RS03080
uniprot id: A0A0M3Q963
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS01830
gene id: 931089:CDES_RS01830
uniprot id: A0A0M5IL70
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

931089:CDES RS02270
gene id: 931089:CDES_RS02270
uniprot id: A0A0M4CK68
names: Subcellular Location Annotation
messages: Cell membrane

931089:CDES RS03300
gene id: 931089:CDES_RS03300
uniprot id: A0A0M4CI71
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS08730
gene id: 931089:CDES_RS08730
uniprot id: A0A0M4CQJ6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

931089:CDES RS09805
gene id: 931089:CDES_RS09805
uniprot id: A0A0M4CMT5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

931089:CDES RS09555
gene id: 931089:CDES_RS09555
uniprot id: A0A0M4CMQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

931089:CDES RS00640
gene id: 931089:CDES_RS00640
uniprot id: A0A0M3Q8X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell membrane

931089:CDES RS02200
gene id: 931089:CDES_RS02200
uniprot id: A0A0M4CGW4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

931089:CDES RS05880
gene id: 931089:CDES_RS05880
uniprot id: A0A0M3Q9I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Membrane

931089:CDES RS12845
gene id: 931089:CDES_RS12845
uniprot id: A0A0M4D077
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS09380
gene id: 931089:CDES_RS09380
uniprot id: A0A0M4CMN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

931089:CDES RS01040
gene id: 931089:CDES_RS01040
uniprot id: A0A0M4CC41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

931089:CDES RS03670
gene id: 931089:CDES_RS03670
uniprot id: A0A0M3Q985
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

931089:CDES RS07660
gene id: 931089:CDES_RS07660
uniprot id: A0A0M4CXJ2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

931089:CDES RS13610
gene id: 931089:CDES_RS13610
uniprot id: A0A0M4CIG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

931089:CDES RS03160
gene id: 931089:CDES_RS03160
uniprot id: A0A0M3Q965
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

931089:CDES RS08350
gene id: 931089:CDES_RS08350
uniprot id: A0A0M4CEA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

931089:CDES RS11250
gene id: 931089:CDES_RS11250
uniprot id: A0A0M4CF67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

931089:CDES RS04485
gene id: 931089:CDES_RS04485
uniprot id: A0A0M4CKY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

931089:CDES RS00520
gene id: 931089:CDES_RS00520
uniprot id: A0A0M4CHD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

931089:CDES RS02210
gene id: 931089:CDES_RS02210
uniprot id: A0A0M3Q933
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

931089:CDES RS08765
gene id: 931089:CDES_RS08765
uniprot id: A0A0M4CXY4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

931089:CDES RS05175
gene id: 931089:CDES_RS05175
uniprot id: A0A0M5IIU1
names: Similarity
messages: Belongs to the LOG family.

931089:CDES RS02870
gene id: 931089:CDES_RS02870
uniprot id: A0A0M4CVK8
names: Similarity
messages: Belongs to the EccD/Snm4 family.

931089:CDES RS06870
gene id: 931089:CDES_RS06870
uniprot id: A0A0M4CDW8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS00555
gene id: 931089:CDES_RS00555
uniprot id: A0A0M4CVD5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

931089:CDES RS03220
gene id: 931089:CDES_RS03220
uniprot id: A0A0M4CH70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

931089:CDES RS02420
gene id: 931089:CDES_RS02420
uniprot id: A0A0M4CEG5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

931089:CDES RS02825
gene id: 931089:CDES_RS02825
uniprot id: A0A0M4CCN1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

931089:CDES RS08640
gene id: 931089:CDES_RS08640
uniprot id: A0A0M4CXW8
names: Similarity
messages: Belongs to the MQO family.

931089:CDES RS03200
gene id: 931089:CDES_RS03200
uniprot id: A0A0M4CNI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS08550
gene id: 931089:CDES_RS08550
uniprot id: A0A0M5IU92
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS07775
gene id: 931089:CDES_RS07775
uniprot id: A0A0M3Q9Q9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS05995
gene id: 931089:CDES_RS05995
uniprot id: A0A0M4CJ25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

931089:CDES RS11240
gene id: 931089:CDES_RS11240
uniprot id: A0A0M3QA12
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

931089:CDES RS13090
gene id: 931089:CDES_RS13090
uniprot id: A0A0M5IGM9
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

931089:CDES RS03960
gene id: 931089:CDES_RS03960
uniprot id: A0A0M4CNV0
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

931089:CDES RS02500
gene id: 931089:CDES_RS02500
uniprot id: A0A0M4CHY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

931089:CDES RS02640
gene id: 931089:CDES_RS02640
uniprot id: A0A0M3Q947
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

931089:CDES RS05200
gene id: 931089:CDES_RS05200
uniprot id: A0A0M4CPB7
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

931089:CDES RS07665
gene id: 931089:CDES_RS07665
uniprot id: A0A0M4CJM5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

931089:CDES RS08425
gene id: 931089:CDES_RS08425
uniprot id: A0A0M3Q9T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

931089:CDES RS10220
gene id: 931089:CDES_RS10220
uniprot id: A0A0M4CH89
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

931089:CDES RS03685
gene id: 931089:CDES_RS03685
uniprot id: A0A0M4CCX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

931089:CDES RS04780
gene id: 931089:CDES_RS04780
uniprot id: A0A0M4CX35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

931089:CDES RS07715
gene id: 931089:CDES_RS07715
uniprot id: A0A0M5IJ23
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

931089:CDES RS13120
gene id: 931089:CDES_RS13120
uniprot id: A0A0M3QAC3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

931089:CDES RS08000
gene id: 931089:CDES_RS08000
uniprot id: A0A0M4CQC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

931089:CDES RS08495
gene id: 931089:CDES_RS08495
uniprot id: A0A0M4CYH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

931089:CDES RS13445
gene id: 931089:CDES_RS13445
uniprot id: A0A0M4CS67
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

931089:CDES RS06545
gene id: 931089:CDES_RS06545
uniprot id: A0A0M3Q9I9
names: Similarity
messages: Belongs to the UPF0434 family.

931089:CDES RS09915
gene id: 931089:CDES_RS09915
uniprot id: A0A0M4CH50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

931089:CDES RS10305
gene id: 931089:CDES_RS10305
uniprot id: A0A0M3Q9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

931089:CDES RS13695
gene id: 931089:CDES_RS13695
uniprot id: A0A0M4CP46
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

931089:CDES RS10640
gene id: 931089:CDES_RS10640
uniprot id: A0A0M4CN47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

931089:CDES RS01565
gene id: 931089:CDES_RS01565
uniprot id: A0A0M3Q8Z2
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS08365
gene id: 931089:CDES_RS08365
uniprot id: A0A0M5IPD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS02650
gene id: 931089:CDES_RS02650
uniprot id: A0A0M4CN99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

931089:CDES RS07950
gene id: 931089:CDES_RS07950
uniprot id: A0A0M4CYB4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

931089:CDES RS09415
gene id: 931089:CDES_RS09415
uniprot id: A0A0M3Q9Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

931089:CDES RS01800
gene id: 931089:CDES_RS01800
uniprot id: A0A0M4CHQ0
names: Similarity
messages: Belongs to the peptidase M1 family.

931089:CDES RS11375
gene id: 931089:CDES_RS11375
uniprot id: A0A0M4CRH2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

931089:CDES RS03270
gene id: 931089:CDES_RS03270
uniprot id: A0A0M4CWH2
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

931089:CDES RS08565
gene id: 931089:CDES_RS08565
uniprot id: A0A0M4CIW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

931089:CDES RS09785
gene id: 931089:CDES_RS09785
uniprot id: A0A0M5IUC5
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS03485
gene id: 931089:CDES_RS03485
uniprot id: A0A0M4CEU4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

931089:CDES RS02475
gene id: 931089:CDES_RS02475
uniprot id: A0A0M4CGY9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

931089:CDES RS10755
gene id: 931089:CDES_RS10755
uniprot id: A0A0M4CR83
names: Similarity
messages: Belongs to the alkaline phosphatase family.

931089:CDES RS06165
gene id: 931089:CDES_RS06165
uniprot id: A0A0M4CDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

931089:CDES RS04470
gene id: 931089:CDES_RS04470
uniprot id: A0A0M3Q9B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

931089:CDES RS05180
gene id: 931089:CDES_RS05180
uniprot id: A0A0M4CWJ8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

931089:CDES RS13075
gene id: 931089:CDES_RS13075
uniprot id: A0A0M4D0A3
names: Similarity
messages: Belongs to the UPF0371 family.

931089:CDES RS02550
gene id: 931089:CDES_RS02550
uniprot id: A0A0M4CK99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

931089:CDES RS06760
gene id: 931089:CDES_RS06760
uniprot id: A0A0M3Q9J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

931089:CDES RS12755
gene id: 931089:CDES_RS12755
uniprot id: A0A0M4CZI3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

931089:CDES RS08040
gene id: 931089:CDES_RS08040
uniprot id: A0A0M4CXP2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS11105
gene id: 931089:CDES_RS11105
uniprot id: A0A0M4CZI6
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS12160
gene id: 931089:CDES_RS12160
uniprot id: A0A0M4CFG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

931089:CDES RS02125
gene id: 931089:CDES_RS02125
uniprot id: A0A0M4CN24
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

931089:CDES RS02855
gene id: 931089:CDES_RS02855
uniprot id: A0A0M4CKE2
names: Similarity
messages: Belongs to the CFA/CMAS family.

931089:CDES RS06930
gene id: 931089:CDES_RS06930
uniprot id: A0A0M3Q9M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

931089:CDES RS12925
gene id: 931089:CDES_RS12925
uniprot id: A0A0M4CI82
names: Similarity
messages: Belongs to the thioredoxin family.

931089:CDES RS07620
gene id: 931089:CDES_RS07620
uniprot id: A0A0M4CQ82
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

931089:CDES RS10715
gene id: 931089:CDES_RS10715
uniprot id: A0A0M4CYQ7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

931089:CDES RS08925
gene id: 931089:CDES_RS08925
uniprot id: A0A0M4CMH6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

931089:CDES RS11345
gene id: 931089:CDES_RS11345
uniprot id: A0A0M5IMC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

931089:CDES RS10625
gene id: 931089:CDES_RS10625
uniprot id: A0A0M4CZC6
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS03475
gene id: 931089:CDES_RS03475
uniprot id: A0A0M4CVU9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

931089:CDES RS09640
gene id: 931089:CDES_RS09640
uniprot id: A0A0M4CH18
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

931089:CDES RS01355
gene id: 931089:CDES_RS01355
uniprot id: A0A0M5II54
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS05040
gene id: 931089:CDES_RS05040
uniprot id: A0A0M3Q9E5
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS04560
gene id: 931089:CDES_RS04560
uniprot id: A0A0M4CF83
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS06585
gene id: 931089:CDES_RS06585
uniprot id: A0A0M4CLP9
names: Similarity
messages: Belongs to the TlyA family.

931089:CDES RS07670
gene id: 931089:CDES_RS07670
uniprot id: A0A0M4CGC4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

931089:CDES RS10170
gene id: 931089:CDES_RS10170
uniprot id: A0A0M4CR18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

931089:CDES RS04650
gene id: 931089:CDES_RS04650
uniprot id: A0A0M4CX18
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

931089:CDES RS08520
gene id: 931089:CDES_RS08520
uniprot id: A0A0M4CXV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

931089:CDES RS13065
gene id: 931089:CDES_RS13065
uniprot id: A0A0M3QAC1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

931089:CDES RS00465
gene id: 931089:CDES_RS00465
uniprot id: A0A0M3Q8V0
names: Similarity
messages: Belongs to the heat shock protein 90 family.

931089:CDES RS12110
gene id: 931089:CDES_RS12110
uniprot id: A0A0M4CK49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

931089:CDES RS06745
gene id: 931089:CDES_RS06745
uniprot id: A0A0M4CDV3
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS05160
gene id: 931089:CDES_RS05160
uniprot id: A0A0M4CHT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

931089:CDES RS07745
gene id: 931089:CDES_RS07745
uniprot id: A0A0M4CQ97
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

931089:CDES RS12085
gene id: 931089:CDES_RS12085
uniprot id: A0A0M3QA82
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

931089:CDES RS03400
gene id: 931089:CDES_RS03400
uniprot id: A0A0M4CH91
names: Similarity
messages: Belongs to the PrpD family.

931089:CDES RS13245
gene id: 931089:CDES_RS13245
uniprot id: A0A0M3QA91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

931089:CDES RS09365
gene id: 931089:CDES_RS09365
uniprot id: A0A0M4CYU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

931089:CDES RS13700
gene id: 931089:CDES_RS13700
uniprot id: A0A0M3QAE7
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS02165
gene id: 931089:CDES_RS02165
uniprot id: A0A0M4CHU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

931089:CDES RS08690
gene id: 931089:CDES_RS08690
uniprot id: A0A0M4CME5
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS02530
gene id: 931089:CDES_RS02530
uniprot id: A0A0M5ITQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

931089:CDES RS13010
gene id: 931089:CDES_RS13010
uniprot id: A0A0M4D094
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

931089:CDES RS08250
gene id: 931089:CDES_RS08250
uniprot id: A0A0M3Q9Q4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

931089:CDES RS04945
gene id: 931089:CDES_RS04945
uniprot id: A0A0M4CFD3
names: Similarity
messages: Belongs to the YjdM family.

931089:CDES RS05685
gene id: 931089:CDES_RS05685
uniprot id: A0A0M3Q9H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

931089:CDES RS12735
gene id: 931089:CDES_RS12735
uniprot id: A0A0M3QAA3
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS04450
gene id: 931089:CDES_RS04450
uniprot id: A0A0M4CF66
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS10035
gene id: 931089:CDES_RS10035
uniprot id: A0A0M4CKH3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

931089:CDES RS00320
gene id: 931089:CDES_RS00320
uniprot id: A0A0M4CDR9
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS09440
gene id: 931089:CDES_RS09440
uniprot id: A0A0M5IRC5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

931089:CDES RS03780
gene id: 931089:CDES_RS03780
uniprot id: A0A0M5IFW0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

931089:CDES RS07845
gene id: 931089:CDES_RS07845
uniprot id: A0A0M4CXL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

931089:CDES RS12525
gene id: 931089:CDES_RS12525
uniprot id: A0A0M4CRW3
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

931089:CDES RS07565
gene id: 931089:CDES_RS07565
uniprot id: A0A0M5IU54
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS08785
gene id: 931089:CDES_RS08785
uniprot id: A0A0M4CEF9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

931089:CDES RS05950
gene id: 931089:CDES_RS05950
uniprot id: A0A0M4CPK8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

931089:CDES RS02560
gene id: 931089:CDES_RS02560
uniprot id: A0A0M4CVG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

931089:CDES RS06400
gene id: 931089:CDES_RS06400
uniprot id: A0A0M4CX21
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS05775
gene id: 931089:CDES_RS05775
uniprot id: A0A0M4CXI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS04125
gene id: 931089:CDES_RS04125
uniprot id: A0A0M3Q9A4
names: Similarity
messages: Belongs to the FPG family.

931089:CDES RS06410
gene id: 931089:CDES_RS06410
uniprot id: A0A0M4CFX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

931089:CDES RS13335
gene id: 931089:CDES_RS13335
uniprot id: A0A0M4CKJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

931089:CDES RS02480
gene id: 931089:CDES_RS02480
uniprot id: A0A0M4CK90
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

931089:CDES RS03450
gene id: 931089:CDES_RS03450
uniprot id: A0A0M3Q978
names: Similarity
messages: Belongs to the AccD/PCCB family.

931089:CDES RS03015
gene id: 931089:CDES_RS03015
uniprot id: A0A0M4CNG3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

931089:CDES RS12535
gene id: 931089:CDES_RS12535
uniprot id: A0A0M5IPR0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS09545
gene id: 931089:CDES_RS09545
uniprot id: A0A0M4CYX3
names: Similarity
messages: Belongs to the peptidase C40 family.

931089:CDES RS02050
gene id: 931089:CDES_RS02050
uniprot id: A0A0M4CEB8
names: Similarity
messages: Belongs to the CsoR family.

931089:CDES RS08450
gene id: 931089:CDES_RS08450
uniprot id: A0A0M5IM47
names: Similarity
messages: Belongs to the PspA/IM30 family.

931089:CDES RS09410
gene id: 931089:CDES_RS09410
uniprot id: A0A0M4CQS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

931089:CDES RS07835
gene id: 931089:CDES_RS07835
uniprot id: A0A0M4CM51
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

931089:CDES RS10970
gene id: 931089:CDES_RS10970
uniprot id: A0A0M5IGI1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

931089:CDES RS08290
gene id: 931089:CDES_RS08290
uniprot id: A0A0M4CEA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

931089:CDES RS03480
gene id: 931089:CDES_RS03480
uniprot id: A0A0M4CI95
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

931089:CDES RS07025
gene id: 931089:CDES_RS07025
uniprot id: A0A0M4CLV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

931089:CDES RS09695
gene id: 931089:CDES_RS09695
uniprot id: A0A0M4CKD1
names: Similarity
messages: Belongs to the heme oxygenase family.

931089:CDES RS03785
gene id: 931089:CDES_RS03785
uniprot id: A0A0M4CVZ3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

931089:CDES RS10815
gene id: 931089:CDES_RS10815
uniprot id: A0A0M4CKS4
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

931089:CDES RS04145
gene id: 931089:CDES_RS04145
uniprot id: A0A0M3Q9A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

931089:CDES RS04030
gene id: 931089:CDES_RS04030
uniprot id: A0A0M4CWS4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

931089:CDES RS08240
gene id: 931089:CDES_RS08240
uniprot id: A0A0M4CYE7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

931089:CDES RS11645
gene id: 931089:CDES_RS11645
uniprot id: A0A0M5IGK3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

931089:CDES RS04230
gene id: 931089:CDES_RS04230
uniprot id: A0A0M4CWV6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

931089:CDES RS10500
gene id: 931089:CDES_RS10500
uniprot id: A0A0M4CJK7
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

931089:CDES RS10080
gene id: 931089:CDES_RS10080
uniprot id: A0A0M3QA07
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

931089:CDES RS04685
gene id: 931089:CDES_RS04685
uniprot id: A0A0M4CIM8
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

931089:CDES RS07595
gene id: 931089:CDES_RS07595
uniprot id: A0A0M4CXI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931089:CDES RS00435
gene id: 931089:CDES_RS00435
uniprot id: A0A0M3Q8W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

931089:CDES RS06825
gene id: 931089:CDES_RS06825
uniprot id: A0A0M4CXW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

931089:CDES RS11690
gene id: 931089:CDES_RS11690
uniprot id: A0A0M4CHS6
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

931089:CDES RS09705
gene id: 931089:CDES_RS09705
uniprot id: A0A0M3Q9Z3
names: Similarity
messages: Belongs to the glutamine synthetase family.

931089:CDES RS06470
gene id: 931089:CDES_RS06470
uniprot id: A0A0M4CJ84
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

931089:CDES RS07675
gene id: 931089:CDES_RS07675
uniprot id: A0A0M3Q9Q5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

931089:CDES RS07825
gene id: 931089:CDES_RS07825
uniprot id: A0A0M3Q9R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

931089:CDES RS03975
gene id: 931089:CDES_RS03975
uniprot id: A0A0M4CWR5
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

931089:CDES RS07085
gene id: 931089:CDES_RS07085
uniprot id: A0A0M4CXZ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931089:CDES RS09395
gene id: 931089:CDES_RS09395
uniprot id: A0A0M3Q9U9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS08630
gene id: 931089:CDES_RS08630
uniprot id: A0A0M4CMD7
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

931089:CDES RS09150
gene id: 931089:CDES_RS09150
uniprot id: A0A0M4CEJ7
names: Similarity
messages: Belongs to the hyi family.

931089:CDES RS07770
gene id: 931089:CDES_RS07770
uniprot id: A0A0M4CM45
names: Similarity
messages: Belongs to the peptidase M24B family.

931089:CDES RS07760
gene id: 931089:CDES_RS07760
uniprot id: A0A0M4CY92
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

931089:CDES RS01365
gene id: 931089:CDES_RS01365
uniprot id: A0A0M4CUY3
names: Similarity
messages: Belongs to the catalase family.

931089:CDES RS11960
gene id: 931089:CDES_RS11960
uniprot id: A0A0M4CFE6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

931089:CDES RS13250
gene id: 931089:CDES_RS13250
uniprot id: A0A0M4CS49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

931089:CDES RS12935
gene id: 931089:CDES_RS12935
uniprot id: A0A0M4CS08
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS03305
gene id: 931089:CDES_RS03305
uniprot id: A0A0M3Q972
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

931089:CDES RS06330
gene id: 931089:CDES_RS06330
uniprot id: A0A0M5IG37
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS09120
gene id: 931089:CDES_RS09120
uniprot id: A0A0M4CMK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

931089:CDES RS12140
gene id: 931089:CDES_RS12140
uniprot id: A0A0M4CZ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

931089:CDES RS11615
gene id: 931089:CDES_RS11615
uniprot id: A0A0M4CZ19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS04050
gene id: 931089:CDES_RS04050
uniprot id: A0A0M5IQW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

931089:CDES RS06505
gene id: 931089:CDES_RS06505
uniprot id: A0A0M4CI97
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

931089:CDES RS04295
gene id: 931089:CDES_RS04295
uniprot id: A0A0M4CHI7
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS03310
gene id: 931089:CDES_RS03310
uniprot id: A0A0M4CES3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

931089:CDES RS11620
gene id: 931089:CDES_RS11620
uniprot id: A0A0M3QA64
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

931089:CDES RS08755
gene id: 931089:CDES_RS08755
uniprot id: A0A0M4CMF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

931089:CDES RS09975
gene id: 931089:CDES_RS09975
uniprot id: A0A0M4CH57
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

931089:CDES RS05365
gene id: 931089:CDES_RS05365
uniprot id: A0A0M4CWM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

931089:CDES RS13585
gene id: 931089:CDES_RS13585
uniprot id: A0A0M4CP35
names: Similarity
messages: Belongs to the thioredoxin family.

931089:CDES RS01190
gene id: 931089:CDES_RS01190
uniprot id: A0A0M4CVL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

931089:CDES RS07985
gene id: 931089:CDES_RS07985
uniprot id: A0A0M4CJR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

931089:CDES RS13490
gene id: 931089:CDES_RS13490
uniprot id: A0A0M4CIE6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

931089:CDES RS11845
gene id: 931089:CDES_RS11845
uniprot id: A0A0M5IUQ2
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS02175
gene id: 931089:CDES_RS02175
uniprot id: A0A0M4CCF9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

931089:CDES RS11155
gene id: 931089:CDES_RS11155
uniprot id: A0A0M4CHL3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

931089:CDES RS06055
gene id: 931089:CDES_RS06055
uniprot id: A0A0M3Q9J0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

931089:CDES RS12005
gene id: 931089:CDES_RS12005
uniprot id: A0A0M4CZ69
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS00970
gene id: 931089:CDES_RS00970
uniprot id: A0A0M4CDZ2
names: Similarity
messages: Belongs to the TPP enzyme family.

931089:CDES RS05850
gene id: 931089:CDES_RS05850
uniprot id: A0A0M4CLG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

931089:CDES RS12070
gene id: 931089:CDES_RS12070
uniprot id: A0A0M4CZ78
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

931089:CDES RS01315
gene id: 931089:CDES_RS01315
uniprot id: A0A0M4CE29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

931089:CDES RS04440
gene id: 931089:CDES_RS04440
uniprot id: A0A0M3Q9B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS09325
gene id: 931089:CDES_RS09325
uniprot id: A0A0M5IJ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

931089:CDES RS02075
gene id: 931089:CDES_RS02075
uniprot id: A0A0M4CW02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

931089:CDES RS07765
gene id: 931089:CDES_RS07765
uniprot id: A0A0M4CIN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

931089:CDES RS08480
gene id: 931089:CDES_RS08480
uniprot id: A0A0M4CEC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

931089:CDES RS02680
gene id: 931089:CDES_RS02680
uniprot id: A0A0M5IIL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

931089:CDES RS02865
gene id: 931089:CDES_RS02865
uniprot id: A0A0M3Q951
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

931089:CDES RS03570
gene id: 931089:CDES_RS03570
uniprot id: A0A0M5IP06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

931089:CDES RS01515
gene id: 931089:CDES_RS01515
uniprot id: A0A0M3Q8Z0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

931089:CDES RS05720
gene id: 931089:CDES_RS05720
uniprot id: A0A0M4CXG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

931089:CDES RS02805
gene id: 931089:CDES_RS02805
uniprot id: A0A0M4CVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

931089:CDES RS10645
gene id: 931089:CDES_RS10645
uniprot id: A0A0M5IMB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

931089:CDES RS09775
gene id: 931089:CDES_RS09775
uniprot id: A0A0M4CER1
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

931089:CDES RS01600
gene id: 931089:CDES_RS01600
uniprot id: A0A0M4CGQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

931089:CDES RS12425
gene id: 931089:CDES_RS12425
uniprot id: A0A0M4CNQ0
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS00440
gene id: 931089:CDES_RS00440
uniprot id: A0A0M5IIE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

931089:CDES RS02700
gene id: 931089:CDES_RS02700
uniprot id: A0A0M4CNA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

931089:CDES RS08970
gene id: 931089:CDES_RS08970
uniprot id: A0A0M5IPF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

931089:CDES RS07680
gene id: 931089:CDES_RS07680
uniprot id: A0A0M4CE46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

931089:CDES RS01560
gene id: 931089:CDES_RS01560
uniprot id: A0A0M4CHM7
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS07375
gene id: 931089:CDES_RS07375
uniprot id: A0A0M3Q9P2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS13615
gene id: 931089:CDES_RS13615
uniprot id: A0A0M4CFX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

931089:CDES RS10030
gene id: 931089:CDES_RS10030
uniprot id: A0A0M3QA05
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

931089:CDES RS11025
gene id: 931089:CDES_RS11025
uniprot id: A0A0M4CRB3
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS00265
gene id: 931089:CDES_RS00265
uniprot id: A0A0M4CBW3
names: Similarity
messages: Belongs to the CsoR family.

931089:CDES RS06125
gene id: 931089:CDES_RS06125
uniprot id: A0A0M5IIX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

931089:CDES RS02280
gene id: 931089:CDES_RS02280
uniprot id: A0A0M4CVD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

931089:CDES RS04970
gene id: 931089:CDES_RS04970
uniprot id: A0A0M3Q9D2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

931089:CDES RS13240
gene id: 931089:CDES_RS13240
uniprot id: A0A0M4CFT4
names: Function
names: Similarity
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

931089:CDES RS10665
gene id: 931089:CDES_RS10665
uniprot id: A0A0M4CHE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

931089:CDES RS01180
gene id: 931089:CDES_RS01180
uniprot id: A0A0M5IL52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

931089:CDES RS02030
gene id: 931089:CDES_RS02030
uniprot id: A0A0M5IIJ4
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS08420
gene id: 931089:CDES_RS08420
uniprot id: A0A0M4CQG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

931089:CDES RS12305
gene id: 931089:CDES_RS12305
uniprot id: A0A0M5IMF8
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS09745
gene id: 931089:CDES_RS09745
uniprot id: A0A0M5IRD3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

931089:CDES RS05860
gene id: 931089:CDES_RS05860
uniprot id: A0A0M3Q9G5
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS11420
gene id: 931089:CDES_RS11420
uniprot id: A0A0M4CL00
names: Similarity
messages: Belongs to the DSD1 family.

931089:CDES RS02710
gene id: 931089:CDES_RS02710
uniprot id: A0A0M3Q944
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

931089:CDES RS13025
gene id: 931089:CDES_RS13025
uniprot id: A0A0M4CNX3
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS10410
gene id: 931089:CDES_RS10410
uniprot id: A0A0M4CHB3
names: Similarity
messages: Belongs to the LOG family.

931089:CDES RS09370
gene id: 931089:CDES_RS09370
uniprot id: A0A0M3Q9X9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

931089:CDES RS05920
gene id: 931089:CDES_RS05920
uniprot id: A0A0M5IR15
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

931089:CDES RS04740
gene id: 931089:CDES_RS04740
uniprot id: A0A0M4CWD3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

931089:CDES RS03800
gene id: 931089:CDES_RS03800
uniprot id: A0A0M4CEY4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

931089:CDES RS06750
gene id: 931089:CDES_RS06750
uniprot id: A0A0M4CPY4
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS00805
gene id: 931089:CDES_RS00805
uniprot id: A0A0M5IFM4
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS07730
gene id: 931089:CDES_RS07730
uniprot id: A0A0M4CJN3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

931089:CDES RS11270
gene id: 931089:CDES_RS11270
uniprot id: A0A0M4CZK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

931089:CDES RS09075
gene id: 931089:CDES_RS09075
uniprot id: A0A0M4CK56
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

931089:CDES RS11335
gene id: 931089:CDES_RS11335
uniprot id: A0A0M3QA16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

931089:CDES RS06530
gene id: 931089:CDES_RS06530
uniprot id: A0A0M4CJ91
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS11570
gene id: 931089:CDES_RS11570
uniprot id: A0A0M3QA62
names: Similarity
messages: Belongs to the DapA family.

931089:CDES RS02965
gene id: 931089:CDES_RS02965
uniprot id: A0A0M3Q955
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

931089:CDES RS08830
gene id: 931089:CDES_RS08830
uniprot id: A0A0M4CXZ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

931089:CDES RS03875
gene id: 931089:CDES_RS03875
uniprot id: A0A0M4CCZ8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

931089:CDES RS01250
gene id: 931089:CDES_RS01250
uniprot id: A0A0M3Q8Y0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

931089:CDES RS07740
gene id: 931089:CDES_RS07740
uniprot id: A0A0M4CE52
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

931089:CDES RS05805
gene id: 931089:CDES_RS05805
uniprot id: A0A0M4CJ01
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

931089:CDES RS10465
gene id: 931089:CDES_RS10465
uniprot id: A0A0M4CKN2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

931089:CDES RS12440
gene id: 931089:CDES_RS12440
uniprot id: A0A0M4CZD3
names: Similarity
messages: Belongs to the AccD/PCCB family.

931089:CDES RS05990
gene id: 931089:CDES_RS05990
uniprot id: A0A0M4CWW5
names: Similarity
messages: Belongs to the isochorismate synthase family.

931089:CDES RS13175
gene id: 931089:CDES_RS13175
uniprot id: A0A0M4CLL9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS00050
gene id: 931089:CDES_RS00050
uniprot id: A0A0M3Q8V4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

931089:CDES RS10855
gene id: 931089:CDES_RS10855
uniprot id: A0A0M4CN71
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS04355
gene id: 931089:CDES_RS04355
uniprot id: A0A0M4CHJ5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

931089:CDES RS07915
gene id: 931089:CDES_RS07915
uniprot id: A0A0M4CXM4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

931089:CDES RS01610
gene id: 931089:CDES_RS01610
uniprot id: A0A0M3Q8Z4
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

931089:CDES RS06535
gene id: 931089:CDES_RS06535
uniprot id: A0A0M4CFY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

931089:CDES RS05420
gene id: 931089:CDES_RS05420
uniprot id: A0A0M4CWN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

931089:CDES RS07605
gene id: 931089:CDES_RS07605
uniprot id: A0A0M3Q9N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

931089:CDES RS01325
gene id: 931089:CDES_RS01325
uniprot id: A0A0M4CMT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

931089:CDES RS08505
gene id: 931089:CDES_RS08505
uniprot id: A0A0M3Q9R4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

931089:CDES RS11665
gene id: 931089:CDES_RS11665
uniprot id: A0A0M4CNG0
names: Similarity
messages: Belongs to the Nth/MutY family.

931089:CDES RS08805
gene id: 931089:CDES_RS08805
uniprot id: A0A0M4CIZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

931089:CDES RS10735
gene id: 931089:CDES_RS10735
uniprot id: A0A0M4CHF5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

931089:CDES RS02410
gene id: 931089:CDES_RS02410
uniprot id: A0A0M3Q940
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

931089:CDES RS09570
gene id: 931089:CDES_RS09570
uniprot id: A0A0M4CKB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

931089:CDES RS05725
gene id: 931089:CDES_RS05725
uniprot id: A0A0M4CI05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

931089:CDES RS03525
gene id: 931089:CDES_RS03525
uniprot id: A0A0M4CKM3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

931089:CDES RS02645
gene id: 931089:CDES_RS02645
uniprot id: A0A0M4CCK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

931089:CDES RS08245
gene id: 931089:CDES_RS08245
uniprot id: A0A0M4CIT1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

931089:CDES RS07590
gene id: 931089:CDES_RS07590
uniprot id: A0A0M5IG74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

931089:CDES RS06595
gene id: 931089:CDES_RS06595
uniprot id: A0A0M4CX48
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

931089:CDES RS02895
gene id: 931089:CDES_RS02895
uniprot id: A0A0M4CND5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

931089:CDES RS07560
gene id: 931089:CDES_RS07560
uniprot id: A0A0M4CQ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

931089:CDES RS10370
gene id: 931089:CDES_RS10370
uniprot id: A0A0M4CZ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

931089:CDES RS00375
gene id: 931089:CDES_RS00375
uniprot id: A0A0M5II28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

931089:CDES RS00290
gene id: 931089:CDES_RS00290
uniprot id: A0A0M4CGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

931089:CDES RS06785
gene id: 931089:CDES_RS06785
uniprot id: A0A0M5IIZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

931089:CDES RS03440
gene id: 931089:CDES_RS03440
uniprot id: A0A0M4CNM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

931089:CDES RS12700
gene id: 931089:CDES_RS12700
uniprot id: A0A0M4CI61
names: Similarity
messages: Belongs to the pyruvate kinase family.

931089:CDES RS04765
gene id: 931089:CDES_RS04765
uniprot id: A0A0M3Q9C6
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS08345
gene id: 931089:CDES_RS08345
uniprot id: A0A0M4CGK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

931089:CDES RS07820
gene id: 931089:CDES_RS07820
uniprot id: A0A0M4CY99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

931089:CDES RS11990
gene id: 931089:CDES_RS11990
uniprot id: A0A0M4CK32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

931089:CDES RS12920
gene id: 931089:CDES_RS12920
uniprot id: A0A0M4CLI7
names: Similarity
messages: Belongs to the PspA/IM30 family.

931089:CDES RS05475
gene id: 931089:CDES_RS05475
uniprot id: A0A0M4CLB7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

931089:CDES RS03335
gene id: 931089:CDES_RS03335
uniprot id: A0A0M4CWI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS03865
gene id: 931089:CDES_RS03865
uniprot id: A0A0M4CEZ2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

931089:CDES RS09215
gene id: 931089:CDES_RS09215
uniprot id: A0A0M3Q9X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

931089:CDES RS06790
gene id: 931089:CDES_RS06790
uniprot id: A0A0M4CX75
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

931089:CDES RS00605
gene id: 931089:CDES_RS00605
uniprot id: A0A0M4CMK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

931089:CDES RS05645
gene id: 931089:CDES_RS05645
uniprot id: A0A0M4CPH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

931089:CDES RS10510
gene id: 931089:CDES_RS10510
uniprot id: A0A0M4CN30
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

931089:CDES RS07705
gene id: 931089:CDES_RS07705
uniprot id: A0A0M3Q9N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

931089:CDES RS11325
gene id: 931089:CDES_RS11325
uniprot id: A0A0M4CZK9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

931089:CDES RS02040
gene id: 931089:CDES_RS02040
uniprot id: A0A0M4CHS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

931089:CDES RS09890
gene id: 931089:CDES_RS09890
uniprot id: A0A0M4CMU4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

931089:CDES RS02905
gene id: 931089:CDES_RS02905
uniprot id: A0A0M4CWB8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

931089:CDES RS08670
gene id: 931089:CDES_RS08670
uniprot id: A0A0M3Q9T7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

931089:CDES RS04820
gene id: 931089:CDES_RS04820
uniprot id: A0A0M4CFB8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

931089:CDES RS00010
gene id: 931089:CDES_RS00010
uniprot id: A0A0M4CGA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

931089:CDES RS00680
gene id: 931089:CDES_RS00680
uniprot id: A0A0M4CVF1
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS04245
gene id: 931089:CDES_RS04245
uniprot id: A0A0M3Q9A7
names: Similarity
messages: Belongs to the peptidase S1C family.

931089:CDES RS07540
gene id: 931089:CDES_RS07540
uniprot id: A0A0M4CJL0
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS08490
gene id: 931089:CDES_RS08490
uniprot id: A0A0M5ILR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

931089:CDES RS09060
gene id: 931089:CDES_RS09060
uniprot id: A0A0M3Q9W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

931089:CDES RS04775
gene id: 931089:CDES_RS04775
uniprot id: A0A0M5IU38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

931089:CDES RS11910
gene id: 931089:CDES_RS11910
uniprot id: A0A0M5IPP4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931089:CDES RS13310
gene id: 931089:CDES_RS13310
uniprot id: A0A0M4CS57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

931089:CDES RS04265
gene id: 931089:CDES_RS04265
uniprot id: A0A0M4CD38
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

931089:CDES RS07720
gene id: 931089:CDES_RS07720
uniprot id: A0A0M4CXK0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS00130
gene id: 931089:CDES_RS00130
uniprot id: A0A0M4CDP8
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS04805
gene id: 931089:CDES_RS04805
uniprot id: A0A0M4CWE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

931089:CDES RS05750
gene id: 931089:CDES_RS05750
uniprot id: A0A0M4CIZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

931089:CDES RS09665
gene id: 931089:CDES_RS09665
uniprot id: A0A0M4CJA4
names: Similarity
messages: Belongs to the RutC family.

931089:CDES RS04255
gene id: 931089:CDES_RS04255
uniprot id: A0A0M4CIH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

931089:CDES RS07055
gene id: 931089:CDES_RS07055
uniprot id: A0A0M4CDY6
names: Similarity
messages: Belongs to the UPF0098 family.

931089:CDES RS09650
gene id: 931089:CDES_RS09650
uniprot id: A0A0M4CQV6
names: Similarity
messages: Belongs to the glutamine synthetase family.

931089:CDES RS07610
gene id: 931089:CDES_RS07610
uniprot id: A0A0M4CGB5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

931089:CDES RS12760
gene id: 931089:CDES_RS12760
uniprot id: A0A0M4CLH2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

931089:CDES RS10905
gene id: 931089:CDES_RS10905
uniprot id: A0A0M4CZG2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

931089:CDES RS06110
gene id: 931089:CDES_RS06110
uniprot id: A0A0M4CXM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

931089:CDES RS09875
gene id: 931089:CDES_RS09875
uniprot id: A0A0M3Q9Z9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

931089:CDES RS05665
gene id: 931089:CDES_RS05665
uniprot id: A0A0M3Q9G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

931089:CDES RS00730
gene id: 931089:CDES_RS00730
uniprot id: A0A0M4CML4
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

931089:CDES RS10190
gene id: 931089:CDES_RS10190
uniprot id: A0A0M4CJG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

931089:CDES RS07505
gene id: 931089:CDES_RS07505
uniprot id: A0A0M3Q9M8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

931089:CDES RS04150
gene id: 931089:CDES_RS04150
uniprot id: A0A0M4CD24
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

931089:CDES RS07500
gene id: 931089:CDES_RS07500
uniprot id: A0A0M5ILN6
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

931089:CDES RS11040
gene id: 931089:CDES_RS11040
uniprot id: A0A0M4CJS3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

931089:CDES RS02785
gene id: 931089:CDES_RS02785
uniprot id: A0A0M3Q952
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

931089:CDES RS03090
gene id: 931089:CDES_RS03090
uniprot id: A0A0M4CWE5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

931089:CDES RS05640
gene id: 931089:CDES_RS05640
uniprot id: A0A0M4CDJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

931089:CDES RS03005
gene id: 931089:CDES_RS03005
uniprot id: A0A0M4CCQ3
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

931089:CDES RS13205
gene id: 931089:CDES_RS13205
uniprot id: A0A0M4CKI4
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS11290
gene id: 931089:CDES_RS11290
uniprot id: A0A0M3QA14
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

931089:CDES RS02385
gene id: 931089:CDES_RS02385
uniprot id: A0A0M4CGY2
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

931089:CDES RS12530
gene id: 931089:CDES_RS12530
uniprot id: A0A0M3QA96
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

931089:CDES RS06965
gene id: 931089:CDES_RS06965
uniprot id: A0A0M4CLU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

931089:CDES RS13235
gene id: 931089:CDES_RS13235
uniprot id: A0A0M4CIB6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS12520
gene id: 931089:CDES_RS12520
uniprot id: A0A0M4CFK9
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

931089:CDES RS10940
gene id: 931089:CDES_RS10940
uniprot id: A0A0M3QA02
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS04210
gene id: 931089:CDES_RS04210
uniprot id: A0A0M4CD32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

931089:CDES RS10450
gene id: 931089:CDES_RS10450
uniprot id: A0A0M5IGF1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

931089:CDES RS01360
gene id: 931089:CDES_RS01360
uniprot id: A0A0M3Q8Y4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

931089:CDES RS06620
gene id: 931089:CDES_RS06620
uniprot id: A0A0M4CPX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

931089:CDES RS13370
gene id: 931089:CDES_RS13370
uniprot id: A0A0M3QAD3
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS10595
gene id: 931089:CDES_RS10595
uniprot id: A0A0M4CYN8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

931089:CDES RS10805
gene id: 931089:CDES_RS10805
uniprot id: A0A0M4CYR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

931089:CDES RS03720
gene id: 931089:CDES_RS03720
uniprot id: A0A0M5IQV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

931089:CDES RS04275
gene id: 931089:CDES_RS04275
uniprot id: A0A0M4CNZ5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

931089:CDES RS10265
gene id: 931089:CDES_RS10265
uniprot id: A0A0M5IJ98
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS07790
gene id: 931089:CDES_RS07790
uniprot id: A0A0M4CJP1
names: Similarity
messages: Belongs to the peptidase A24 family.

931089:CDES RS03290
gene id: 931089:CDES_RS03290
uniprot id: A0A0M5IIN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

931089:CDES RS08775
gene id: 931089:CDES_RS08775
uniprot id: A0A0M4CK13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

931089:CDES RS00750
gene id: 931089:CDES_RS00750
uniprot id: A0A0M4CGH2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

931089:CDES RS01350
gene id: 931089:CDES_RS01350
uniprot id: A0A0M4CJV8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

931089:CDES RS10075
gene id: 931089:CDES_RS10075
uniprot id: A0A0M4CMW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

931089:CDES RS03405
gene id: 931089:CDES_RS03405
uniprot id: A0A0M3Q976
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

931089:CDES RS11120
gene id: 931089:CDES_RS11120
uniprot id: A0A0M3QA46
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS01255
gene id: 931089:CDES_RS01255
uniprot id: A0A0M4CMS6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

931089:CDES RS06525
gene id: 931089:CDES_RS06525
uniprot id: A0A0M4CX39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

931089:CDES RS07575
gene id: 931089:CDES_RS07575
uniprot id: A0A0M3Q9Q1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

931089:CDES RS07920
gene id: 931089:CDES_RS07920
uniprot id: A0A0M4CJQ7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

931089:CDES RS06335
gene id: 931089:CDES_RS06335
uniprot id: A0A0M4CX13
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

931089:CDES RS09500
gene id: 931089:CDES_RS09500
uniprot id: A0A0M4CMP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

931089:CDES RS11765
gene id: 931089:CDES_RS11765
uniprot id: A0A0M4CRL9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

931089:CDES RS05230
gene id: 931089:CDES_RS05230
uniprot id: A0A0M3Q9F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

931089:CDES RS00220
gene id: 931089:CDES_RS00220
uniprot id: A0A0M4CVA6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

931089:CDES RS12415
gene id: 931089:CDES_RS12415
uniprot id: A0A0M4D007
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

931089:CDES RS03285
gene id: 931089:CDES_RS03285
uniprot id: A0A0M4CKJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

931089:CDES RS07645
gene id: 931089:CDES_RS07645
uniprot id: A0A0M4CM31
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

931089:CDES RS04815
gene id: 931089:CDES_RS04815
uniprot id: A0A0M3Q9C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

931089:CDES RS11825
gene id: 931089:CDES_RS11825
uniprot id: A0A0M4CHU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

931089:CDES RS03000
gene id: 931089:CDES_RS03000
uniprot id: A0A0M4CEN7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

931089:CDES RS08940
gene id: 931089:CDES_RS08940
uniprot id: A0A0M4CY12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

931089:CDES RS04745
gene id: 931089:CDES_RS04745
uniprot id: A0A0M4CIN4
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

931089:CDES RS01595
gene id: 931089:CDES_RS01595
uniprot id: A0A0M4CVS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

931089:CDES RS01195
gene id: 931089:CDES_RS01195
uniprot id: A0A0M4CGL6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

931089:CDES RS01955
gene id: 931089:CDES_RS01955
uniprot id: A0A0M4CGT9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

931089:CDES RS05235
gene id: 931089:CDES_RS05235
uniprot id: A0A0M5ILV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

931089:CDES RS12280
gene id: 931089:CDES_RS12280
uniprot id: A0A0M3QA90
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS12025
gene id: 931089:CDES_RS12025
uniprot id: A0A0M4CFF4
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS03330
gene id: 931089:CDES_RS03330
uniprot id: A0A0M5IFU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

931089:CDES RS13440
gene id: 931089:CDES_RS13440
uniprot id: A0A0M4CFV3
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS11775
gene id: 931089:CDES_RS11775
uniprot id: A0A0M5IUI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

931089:CDES RS09470
gene id: 931089:CDES_RS09470
uniprot id: A0A0M4CEM6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

931089:CDES RS03085
gene id: 931089:CDES_RS03085
uniprot id: A0A0M5ILA2
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS00815
gene id: 931089:CDES_RS00815
uniprot id: A0A0M4CGH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

931089:CDES RS01675
gene id: 931089:CDES_RS01675
uniprot id: A0A0M3Q8Z6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

931089:CDES RS09530
gene id: 931089:CDES_RS09530
uniprot id: A0A0M4CQU2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

931089:CDES RS11715
gene id: 931089:CDES_RS11715
uniprot id: A0A0M4CZR0
names: Similarity
messages: Belongs to the pantothenate synthetase family.

931089:CDES RS02275
gene id: 931089:CDES_RS02275
uniprot id: A0A0M5II83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS04310
gene id: 931089:CDES_RS04310
uniprot id: A0A0M4CW70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

931089:CDES RS09755
gene id: 931089:CDES_RS09755
uniprot id: A0A0M3Q9Z5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

931089:CDES RS07695
gene id: 931089:CDES_RS07695
uniprot id: A0A0M4CY82
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS07030
gene id: 931089:CDES_RS07030
uniprot id: A0A0M3Q9M7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

931089:CDES RS10495
gene id: 931089:CDES_RS10495
uniprot id: A0A0M4CZA4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

931089:CDES RS08575
gene id: 931089:CDES_RS08575
uniprot id: A0A0M5IG99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

931089:CDES RS08570
gene id: 931089:CDES_RS08570
uniprot id: A0A0M3Q9T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

931089:CDES RS08945
gene id: 931089:CDES_RS08945
uniprot id: A0A0M4CK40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

931089:CDES RS12820
gene id: 931089:CDES_RS12820
uniprot id: A0A0M4CLH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

931089:CDES RS03145
gene id: 931089:CDES_RS03145
uniprot id: A0A0M5ITS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

931089:CDES RS11905
gene id: 931089:CDES_RS11905
uniprot id: A0A0M4CRN3
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS09005
gene id: 931089:CDES_RS09005
uniprot id: A0A0M3Q9W5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

931089:CDES RS12550
gene id: 931089:CDES_RS12550
uniprot id: A0A0M4CNS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

931089:CDES RS12300
gene id: 931089:CDES_RS12300
uniprot id: A0A0M4CNN5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

931089:CDES RS00800
gene id: 931089:CDES_RS00800
uniprot id: A0A0M3Q8Y1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

931089:CDES RS02370
gene id: 931089:CDES_RS02370
uniprot id: A0A0M4CN60
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS05005
gene id: 931089:CDES_RS05005
uniprot id: A0A0M4CIR0
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS10825
gene id: 931089:CDES_RS10825
uniprot id: A0A0M4CF18
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

931089:CDES RS06180
gene id: 931089:CDES_RS06180
uniprot id: A0A0M4CXN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

931089:CDES RS11075
gene id: 931089:CDES_RS11075
uniprot id: A0A0M3QA44
names: Similarity
messages: Belongs to the phosphohexose mutase family.

931089:CDES RS08895
gene id: 931089:CDES_RS08895
uniprot id: A0A0M4CK33
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

931089:CDES RS03665
gene id: 931089:CDES_RS03665
uniprot id: A0A0M4CVX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

931089:CDES RS10780
gene id: 931089:CDES_RS10780
uniprot id: A0A0M3Q9Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

931089:CDES RS05565
gene id: 931089:CDES_RS05565
uniprot id: A0A0M3Q9F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

931089:CDES RS02795
gene id: 931089:CDES_RS02795
uniprot id: A0A0M4CKD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

931089:CDES RS02890
gene id: 931089:CDES_RS02890
uniprot id: A0A0M4CCP0
names: Similarity
messages: Belongs to the WXG100 family.

931089:CDES RS04315
gene id: 931089:CDES_RS04315
uniprot id: A0A0M4CII4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

931089:CDES RS10400
gene id: 931089:CDES_RS10400
uniprot id: A0A0M4CKM4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

931089:CDES RS01130
gene id: 931089:CDES_RS01130
uniprot id: A0A0M3Q8X6
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS04490
gene id: 931089:CDES_RS04490
uniprot id: A0A0M3Q9B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

931089:CDES RS04750
gene id: 931089:CDES_RS04750
uniprot id: A0A0M4CFA8
names: Similarity
messages: Belongs to the FBPase class 2 family.

931089:CDES RS09350
gene id: 931089:CDES_RS09350
uniprot id: A0A0M4CEL2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

931089:CDES RS06510
gene id: 931089:CDES_RS06510
uniprot id: A0A0M4CLP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

931089:CDES RS02815
gene id: 931089:CDES_RS02815
uniprot id: A0A0M3Q948
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

931089:CDES RS06650
gene id: 931089:CDES_RS06650
uniprot id: A0A0M5IG45
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

931089:CDES RS10245
gene id: 931089:CDES_RS10245
uniprot id: A0A0M4CZ74
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

931089:CDES RS01765
gene id: 931089:CDES_RS01765
uniprot id: A0A0M5IFQ1
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

931089:CDES RS12170
gene id: 931089:CDES_RS12170
uniprot id: A0A0M5IUR1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

931089:CDES RS09210
gene id: 931089:CDES_RS09210
uniprot id: A0A0M4CGW6
names: Similarity
messages: Belongs to the IMPACT family.

931089:CDES RS05150
gene id: 931089:CDES_RS05150
uniprot id: A0A0M4CPA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

931089:CDES RS12470
gene id: 931089:CDES_RS12470
uniprot id: A0A0M5IUS0
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

931089:CDES RS05900
gene id: 931089:CDES_RS05900
uniprot id: A0A0M4CXJ3
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS10605
gene id: 931089:CDES_RS10605
uniprot id: A0A0M4CHD7
names: Similarity
messages: Belongs to the peptidase M1 family.

931089:CDES RS08500
gene id: 931089:CDES_RS08500
uniprot id: A0A0M4CIV8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS03695
gene id: 931089:CDES_RS03695
uniprot id: A0A0M3Q988
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

931089:CDES RS05930
gene id: 931089:CDES_RS05930
uniprot id: A0A0M3Q9I6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931089:CDES RS06655
gene id: 931089:CDES_RS06655
uniprot id: A0A0M3Q9J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

931089:CDES RS03155
gene id: 931089:CDES_RS03155
uniprot id: A0A0M4CH63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

931089:CDES RS06190
gene id: 931089:CDES_RS06190
uniprot id: A0A0M3Q9H5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

931089:CDES RS02215
gene id: 931089:CDES_RS02215
uniprot id: A0A0M5IFR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

931089:CDES RS02945
gene id: 931089:CDES_RS02945
uniprot id: A0A0M4CEM9
names: Similarity
messages: Belongs to the peptidase S33 family.

931089:CDES RS10005
gene id: 931089:CDES_RS10005
uniprot id: A0A0M4CJE4
names: Similarity
messages: Belongs to the disproportionating enzyme family.

931089:CDES RS05620
gene id: 931089:CDES_RS05620
uniprot id: A0A0M4CWQ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

931089:CDES RS11050
gene id: 931089:CDES_RS11050
uniprot id: A0A0M3QA06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

931089:CDES RS00250
gene id: 931089:CDES_RS00250
uniprot id: A0A0M4CHA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

931089:CDES RS14485
gene id: 931089:CDES_RS14485
uniprot id: A0A0M4CHR5
names: Subcellular Location Annotation
messages: Membrane

931089:CDES RS10530
gene id: 931089:CDES_RS10530
uniprot id: A0A0M4CKN9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

931089:CDES RS08740
gene id: 931089:CDES_RS08740
uniprot id: A0A0M4CYL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

931089:CDES RS11180
gene id: 931089:CDES_RS11180
uniprot id: A0A0M4CRC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

931089:CDES RS07700
gene id: 931089:CDES_RS07700
uniprot id: A0A0M4CIN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

931089:CDES RS04505
gene id: 931089:CDES_RS04505
uniprot id: A0A0M4CIK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

931089:CDES RS02740
gene id: 931089:CDES_RS02740
uniprot id: A0A0M4CVJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

931089:CDES RS11265
gene id: 931089:CDES_RS11265
uniprot id: A0A0M5IPM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

931089:CDES RS09220
gene id: 931089:CDES_RS09220
uniprot id: A0A0M4CEK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

931089:CDES RS07650
gene id: 931089:CDES_RS07650
uniprot id: A0A0M5IIP9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

931089:CDES RS09385
gene id: 931089:CDES_RS09385
uniprot id: A0A0M4CY75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

931089:CDES RS13830
gene id: 931089:CDES_RS13830
uniprot id: A0A0M3Q8X1
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.