9305:S100G
gene id: 9305:S100G
uniprot id: A0A7N4UY54
names: Similarity
messages: Belongs to the S-100 family.

9305:MFAP3
gene id: 9305:MFAP3
uniprot id: G3VEW9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:CTBP1
gene id: 9305:CTBP1
uniprot id: G3WAR2
uniprot id: G3WAR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

9305:BARX2
gene id: 9305:BARX2
uniprot id: G3VXN4
names: Subcellular Location Annotation
messages: Nucleus

9305:SLC17A6
gene id: 9305:SLC17A6
uniprot id: A0A7N4NZY2
names: Subcellular Location Annotation
messages: Membrane

9305:SPRY2
gene id: 9305:SPRY2
uniprot id: A0A7N4PFP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: ruffle membrane

9305:LOC100924365
gene id: 9305:LOC100924365
uniprot id: G3VPR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:IL6R
gene id: 9305:IL6R
uniprot id: G3WLK1
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.

9305:GDF9
gene id: 9305:GDF9
uniprot id: G3WI32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

9305:ND6
gene id: 9305:ND6
uniprot id: G1FKC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

9305:FGFR1OP2
gene id: 9305:FGFR1OP2
uniprot id: G3W7M1
uniprot id: G3W7M2
names: Similarity
messages: Belongs to the SIKE family.

9305:SPOP
gene id: 9305:SPOP
uniprot id: A0A7N4PZC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

9305:PNMT
gene id: 9305:PNMT
uniprot id: A0A7N4PKM4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

9305:CCDC90B
gene id: 9305:CCDC90B
uniprot id: G3VEI3
names: Similarity
messages: Belongs to the CCDC90 family.

9305:TACR1
gene id: 9305:TACR1
uniprot id: A0A7N4V519
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

9305:NTMT1
gene id: 9305:NTMT1
uniprot id: G3WAY1
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

9305:SYNE3
gene id: 9305:SYNE3
uniprot id: A0A7N4NN44
names: Similarity
messages: Belongs to the nesprin family.

9305:TCP11L2
gene id: 9305:TCP11L2
uniprot id: A0A7N4PDJ9
names: Similarity
messages: Belongs to the TCP11 family.

9305:SVOP
gene id: 9305:SVOP
uniprot id: G3WDW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

9305:INPP1
gene id: 9305:INPP1
uniprot id: A0A7N4UYJ6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9305:CDH12
gene id: 9305:CDH12
uniprot id: G3W548
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9305:CBS
gene id: 9305:CBS
uniprot id: A0A7N4NYN7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

9305:CLUAP1
gene id: 9305:CLUAP1
uniprot id: G3WRK6
uniprot id: G3WRK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

9305:AGPAT1
gene id: 9305:AGPAT1
uniprot id: A0A7N4V747
uniprot id: G3W9I6
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

9305:CWC25
gene id: 9305:CWC25
uniprot id: G3WY51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

9305:LOC100921013
gene id: 9305:LOC100921013
uniprot id: G3VXL3
uniprot id: G3VXL4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

9305:PLOD2
gene id: 9305:PLOD2
uniprot id: G3WYU3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9305:SELL
gene id: 9305:SELL
uniprot id: A0A7N4V5X1
uniprot id: G3W9F5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:SPTLC3
gene id: 9305:SPTLC3
uniprot id: G3W945
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

9305:LOC116419006
gene id: 9305:LOC116419006
uniprot id: A0A7N4NWS5
uniprot id: A0A7N4UY15
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

9305:LOC100934514
gene id: 9305:LOC100934514
uniprot id: G3WD05
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

9305:GBA
gene id: 9305:GBA
uniprot id: G3W179
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

9305:METTL2A
gene id: 9305:METTL2A
uniprot id: A0A7N4PKX9
uniprot id: G3VJH1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

9305:CCNY
gene id: 9305:CCNY
uniprot id: A0A7N4PML3
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

9305:LOC100925518
gene id: 9305:LOC100925518
uniprot id: G3VE78
names: Subcellular Location Annotation
messages: Membrane

9305:ODR4
gene id: 9305:ODR4
uniprot id: G3WS48
names: Function
names: Similarity
messages: Belongs to the ODR-4 family.
messages: May play a role in the trafficking of a subset of G-protein coupled receptors.

9305:LOC100931389
gene id: 9305:LOC100931389
uniprot id: A0A7N4UY05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CHMP4A
gene id: 9305:CHMP4A
uniprot id: A0A7N4V7P0
names: Similarity
messages: Belongs to the SNF7 family.

9305:GPHB5
gene id: 9305:GPHB5
uniprot id: A0A7N4UYL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9305:LOC100919708
gene id: 9305:LOC100919708
uniprot id: G3VHL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100930807
gene id: 9305:LOC100930807
uniprot id: A0A7N4NXQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:WASHC1
gene id: 9305:WASHC1
uniprot id: G3WP97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

9305:TMEM33
gene id: 9305:TMEM33
uniprot id: G3WPE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

9305:CHAC2
gene id: 9305:CHAC2
uniprot id: G3WPZ6
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

9305:LOC100915447
gene id: 9305:LOC100915447
uniprot id: G3WM46
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria.
messages: Microsome membrane
messages: Mitochondrion inner membrane
messages: The omega-1 hydroxylase activity is stimulated by cytochrome b5.

9305:KHDC4
gene id: 9305:KHDC4
uniprot id: G3WHD1
names: Similarity
messages: Belongs to the KHDC4 family.

9305:NMBR
gene id: 9305:NMBR
uniprot id: G3VSN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PPP1R1A
gene id: 9305:PPP1R1A
uniprot id: G3WGS6
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

9305:SPRY1
gene id: 9305:SPRY1
uniprot id: A0A7N4PFQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: Cytoplasm
messages: Membrane

9305:SEC61A2
gene id: 9305:SEC61A2
uniprot id: G3W5D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:AVIL
gene id: 9305:AVIL
uniprot id: G3W7C3
names: Similarity
messages: Belongs to the villin/gelsolin family.

9305:KRR1
gene id: 9305:KRR1
uniprot id: G3VF94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

9305:IMPACT
gene id: 9305:IMPACT
uniprot id: A0A7N4PEV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

9305:HSD17B3
gene id: 9305:HSD17B3
uniprot id: A0A7N4PM36
uniprot id: G3VZQ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9305:CER1
gene id: 9305:CER1
uniprot id: G3WY53
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:DGLUCY
gene id: 9305:DGLUCY
uniprot id: G3WIZ8
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

9305:CHRNA1
gene id: 9305:CHRNA1
uniprot id: A0A7N4NK50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9305:ARRDC3
gene id: 9305:ARRDC3
uniprot id: G3WH02
names: Similarity
messages: Belongs to the arrestin family.

9305:PEX7
gene id: 9305:PEX7
uniprot id: G3WMB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

9305:ATP5F1A
gene id: 9305:ATP5F1A
uniprot id: G3WXU6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

9305:PSD4
gene id: 9305:PSD4
uniprot id: G3WDA0
uniprot id: G3WDA1
names: Subcellular Location Annotation
messages: ruffle membrane

9305:RPS20
gene id: 9305:RPS20
uniprot id: A0A7N4PJW7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

9305:LOC100919663
gene id: 9305:LOC100919663
uniprot id: A0A7N4PP98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9305:CASR
gene id: 9305:CASR
uniprot id: G3WHI5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:SLC25A30
gene id: 9305:SLC25A30
uniprot id: A0A7N4NUQ7
uniprot id: G3VLT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9305:HTR2A
gene id: 9305:HTR2A
uniprot id: G3W3N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

9305:TUBB4B
gene id: 9305:TUBB4B
uniprot id: A0A7N4V388
uniprot id: G3W1X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9305:NOX4
gene id: 9305:NOX4
uniprot id: A0A7N4PLA0
uniprot id: G3VR45
names: Subcellular Location Annotation
messages: Membrane

9305:SLC39A8
gene id: 9305:SLC39A8
uniprot id: A0A7N4P4N0
names: Subcellular Location Annotation
messages: Membrane

9305:PCNA
gene id: 9305:PCNA
uniprot id: A0A7N4V2Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

9305:LOC100916674
gene id: 9305:LOC100916674
uniprot id: G3VSG7
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

9305:PLLP
gene id: 9305:PLLP
uniprot id: G3WNY0
names: Subcellular Location Annotation
messages: Membrane

9305:GAD1
gene id: 9305:GAD1
uniprot id: G3WDA8
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9305:AWAT2
gene id: 9305:AWAT2
uniprot id: G3W0E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

9305:LOC100917158
gene id: 9305:LOC100917158
uniprot id: G3VTN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100913664
gene id: 9305:LOC100913664
uniprot id: A0A7N4PRX4
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:GTF2A2
gene id: 9305:GTF2A2
uniprot id: A0A7N4NZ67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

9305:RPS29
gene id: 9305:RPS29
uniprot id: A0A7N4Q1I5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Component of the 40S small ribosomal subunit.

9305:DOLPP1
gene id: 9305:DOLPP1
uniprot id: G3X3U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

9305:PAQR8
gene id: 9305:PAQR8
uniprot id: G3WKB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9305:UBE2N
gene id: 9305:UBE2N
uniprot id: A0A7N4NHS9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9305:PLAU
gene id: 9305:PLAU
uniprot id: G3W3Y6
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.

9305:NPM3
gene id: 9305:NPM3
uniprot id: G3W389
names: Similarity
messages: Belongs to the nucleoplasmin family.

9305:AOX1
gene id: 9305:AOX1
uniprot id: A0A7N4UZY8
uniprot id: G3WVK3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

9305:CC2D1A
gene id: 9305:CC2D1A
uniprot id: G3W9K7
uniprot id: G3W9K8
names: Similarity
messages: Belongs to the CC2D1 family.

9305:VEGFD
gene id: 9305:VEGFD
uniprot id: G3VQP3
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

9305:NKX3-1
gene id: 9305:NKX3-1
uniprot id: G3WS21
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100928062
gene id: 9305:LOC100928062
uniprot id: G3VI51
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:SRD5A2
gene id: 9305:SRD5A2
uniprot id: A0A7N4NWS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

9305:LOC100924887
gene id: 9305:LOC100924887
uniprot id: A0A7N4P3M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ATP5MG
gene id: 9305:ATP5MG
uniprot id: A0A7N4PNJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

9305:LOC100925430
gene id: 9305:LOC100925430
uniprot id: G3VQT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ARRB2
gene id: 9305:ARRB2
uniprot id: G3VAC5
names: Similarity
messages: Belongs to the arrestin family.

9305:GCDH
gene id: 9305:GCDH
uniprot id: G3WR30
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9305:CD99
gene id: 9305:CD99
uniprot id: A0A7N4PR11
names: Similarity
messages: Belongs to the CD99 family.

9305:LOC100923433
gene id: 9305:LOC100923433
uniprot id: G3WUI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation.
messages: Microsome membrane

9305:LOC100924334
gene id: 9305:LOC100924334
uniprot id: G3VHA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:A2M
gene id: 9305:A2M
uniprot id: G3VI84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

9305:LOC100922043
gene id: 9305:LOC100922043
uniprot id: G3VEH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100915155
gene id: 9305:LOC100915155
uniprot id: G3VWF0
names: Similarity
messages: Belongs to the actin family.

9305:CDC123
gene id: 9305:CDC123
uniprot id: G3W7K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

9305:SLC34A3
gene id: 9305:SLC34A3
uniprot id: G3W2I6
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

9305:LOC100916737
gene id: 9305:LOC100916737
uniprot id: G3VFV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9305:ASB17
gene id: 9305:ASB17
uniprot id: G3VXA7
names: Function
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

9305:LOC100917840
gene id: 9305:LOC100917840
uniprot id: A0A7N4P369
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9305:DEGS2
gene id: 9305:DEGS2
uniprot id: G3WRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:KPNA1
gene id: 9305:KPNA1
uniprot id: A0A7N4PSL9
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

9305:POLR3A
gene id: 9305:POLR3A
uniprot id: A0A7N4P5U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

9305:NSA2
gene id: 9305:NSA2
uniprot id: G3WZG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

9305:PDIK1L
gene id: 9305:PDIK1L
uniprot id: G3W421
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:CFAP298
gene id: 9305:CFAP298
uniprot id: G3W6P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

9305:RDH13
gene id: 9305:RDH13
uniprot id: G3VHT0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9305:PLET1
gene id: 9305:PLET1
uniprot id: A0A7N4PSV7
names: Function
messages: Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.

9305:LOC100924515
gene id: 9305:LOC100924515
uniprot id: A0A7N4PBP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CTSB
gene id: 9305:CTSB
uniprot id: G3W5Z0
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9305:IBSP
gene id: 9305:IBSP
uniprot id: G3VPY7
names: Function
names: Subcellular Location Annotation
messages: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
messages: Secreted

9305:BDKRB1
gene id: 9305:BDKRB1
uniprot id: G3VUF0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

9305:PABPC4
gene id: 9305:PABPC4
uniprot id: A0A7N4PXU5
uniprot id: G3X150
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

9305:BSX
gene id: 9305:BSX
uniprot id: A0A7N4NKV5
names: Subcellular Location Annotation
messages: Nucleus

9305:PDLIM3
gene id: 9305:PDLIM3
uniprot id: G3WFZ3
uniprot id: G3WFZ4
names: Subcellular Location Annotation
messages: Z line

9305:CA14
gene id: 9305:CA14
uniprot id: G3W4T4
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

9305:CCN3
gene id: 9305:CCN3
uniprot id: G3WY44
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:CNGA4
gene id: 9305:CNGA4
uniprot id: G3VKE7
names: Subcellular Location Annotation
messages: Membrane

9305:POLR2K
gene id: 9305:POLR2K
uniprot id: A0A7N4P3Q7
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

9305:PDIA3
gene id: 9305:PDIA3
uniprot id: G3WNM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

9305:CA10
gene id: 9305:CA10
uniprot id: A0A7N4Q1G9
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

9305:JPT1
gene id: 9305:JPT1
uniprot id: A0A7N4NIG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

9305:APP
gene id: 9305:APP
uniprot id: G3VGV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Endoplasmic reticulum
messages: Endosome
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Golgi apparatus
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
messages: Nucleus
messages: Perikaryon
messages: Secreted
messages: The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis.
messages: Vesicle
messages: clathrin-coated pit
messages: growth cone

9305:LOC100915965
gene id: 9305:LOC100915965
uniprot id: G3WFZ8
names: Subcellular Location Annotation
messages: Membrane

9305:CCNT1
gene id: 9305:CCNT1
uniprot id: G3VXD0
names: Similarity
messages: Belongs to the cyclin family. Cyclin C subfamily.

9305:LOC100916784
gene id: 9305:LOC100916784
uniprot id: A0A7N4Q053
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

9305:YJU2
gene id: 9305:YJU2
uniprot id: G3W9R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

9305:CALCRL
gene id: 9305:CALCRL
uniprot id: A0A7N4PKP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

9305:MMAA
gene id: 9305:MMAA
uniprot id: G3VR08
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

9305:CENPA
gene id: 9305:CENPA
uniprot id: G3W9B0
names: Similarity
messages: Belongs to the histone H3 family.

9305:CD2
gene id: 9305:CD2
uniprot id: G3WZT7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:LIPT1
gene id: 9305:LIPT1
uniprot id: G3W3X3
names: Similarity
messages: Belongs to the LplA family.

9305:LOC100917932
gene id: 9305:LOC100917932
uniprot id: A0A7N4PTK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:HAPLN2
gene id: 9305:HAPLN2
uniprot id: A0A7N4NXA6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LGI1
gene id: 9305:LGI1
uniprot id: G3WVC8
names: Subcellular Location Annotation
messages: Secreted

9305:INTS13
gene id: 9305:INTS13
uniprot id: A0A7N4PG55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the asunder family.
messages: Cytoplasm
messages: Nucleus

9305:LOC100915322
gene id: 9305:LOC100915322
uniprot id: G3WNV3
names: Similarity
messages: Belongs to the peptidase M10A family.

9305:CPSF3
gene id: 9305:CPSF3
uniprot id: G3VY42
names: Subcellular Location Annotation
messages: Nucleus

9305:HDC
gene id: 9305:HDC
uniprot id: G3WC78
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9305:DUSP9
gene id: 9305:DUSP9
uniprot id: G3W0X4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9305:TGIF1
gene id: 9305:TGIF1
uniprot id: A0A7N4NKD6
uniprot id: A0A7N4Q094
names: Subcellular Location Annotation
messages: Nucleus

9305:SH3YL1
gene id: 9305:SH3YL1
uniprot id: A0A7N4NZQ9
uniprot id: G3VU84
names: Similarity
names: Subunit
messages: Belongs to the SH3YL1 family.
messages: Interacts with SH3D19.

9305:BASP1
gene id: 9305:BASP1
uniprot id: A0A7N4NZ99
names: Similarity
messages: Belongs to the BASP1 family.

9305:OLFM4
gene id: 9305:OLFM4
uniprot id: G3WXX4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:CCNB2
gene id: 9305:CCNB2
uniprot id: G3WPD4
names: Similarity
messages: Belongs to the cyclin family.

9305:SLC25A15
gene id: 9305:SLC25A15
uniprot id: G3W0M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9305:TPM1
gene id: 9305:TPM1
uniprot id: A0A7N4PQB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9305:CALB1
gene id: 9305:CALB1
uniprot id: A0A7N4P2M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calbindin family.
messages: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
messages: Interacts with RANBP9.

9305:DNASE1
gene id: 9305:DNASE1
uniprot id: G3WP67
names: Similarity
messages: Belongs to the DNase I family.

9305:LOC100928117
gene id: 9305:LOC100928117
uniprot id: A0A7N4NHQ5
names: Subcellular Location Annotation
messages: Membrane

9305:CLCA2
gene id: 9305:CLCA2
uniprot id: G3VY26
names: Similarity
messages: Belongs to the CLCR family.

9305:RNASEH2B
gene id: 9305:RNASEH2B
uniprot id: A0A7N4Q0J0
uniprot id: G3WUG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

9305:STAM2
gene id: 9305:STAM2
uniprot id: A0A7N4PCK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

9305:FAM163A
gene id: 9305:FAM163A
uniprot id: A0A7N4NFQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

9305:GRAP2
gene id: 9305:GRAP2
uniprot id: A0A7N4NRG3
names: Similarity
messages: Belongs to the GRB2/sem-5/DRK family.

9305:SLC25A51
gene id: 9305:SLC25A51
uniprot id: A0A7N4PC66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9305:GABRR2
gene id: 9305:GABRR2
uniprot id: A0A7N4NS30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9305:C1H5orf63
gene id: 9305:C1H5orf63
uniprot id: A0A7N4Q0S6
names: Similarity
messages: Belongs to the glutaredoxin family.

9305:GALNT16
gene id: 9305:GALNT16
uniprot id: G3VX26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9305:LOC100926074
gene id: 9305:LOC100926074
uniprot id: A0A7N4PMA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:RARS2
gene id: 9305:RARS2
uniprot id: G3WA78
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9305:RHCG
gene id: 9305:RHCG
uniprot id: G3WNU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9305:GABRB2
gene id: 9305:GABRB2
uniprot id: A0A7N4P183
uniprot id: G3VMU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9305:TSPAN17
gene id: 9305:TSPAN17
uniprot id: A0A7N4NPB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9305:LOC100914950
gene id: 9305:LOC100914950
uniprot id: G3W5I9
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

9305:HOXD10
gene id: 9305:HOXD10
uniprot id: G3WTV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9305:P2RX3
gene id: 9305:P2RX3
uniprot id: G3WNT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9305:STARD5
gene id: 9305:STARD5
uniprot id: A0A7N4V068
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

9305:CDC42
gene id: 9305:CDC42
uniprot id: A0A7N4UZU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

9305:HSD17B13
gene id: 9305:HSD17B13
uniprot id: G3VDR1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9305:IWS1
gene id: 9305:IWS1
uniprot id: G3VFB5
names: Subcellular Location Annotation
messages: Nucleus

9305:NID2
gene id: 9305:NID2
uniprot id: A0A7N4P8D1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

9305:KCNG2
gene id: 9305:KCNG2
uniprot id: A0A7N4NN69
names: Subcellular Location Annotation
messages: Membrane

9305:NKAIN4
gene id: 9305:NKAIN4
uniprot id: G3W658
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

9305:LOC100933824
gene id: 9305:LOC100933824
uniprot id: G3WR51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

9305:LOC100925546
gene id: 9305:LOC100925546
uniprot id: G3X112
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PPP1R14D
gene id: 9305:PPP1R14D
uniprot id: G3WTH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.

9305:SLU7
gene id: 9305:SLU7
uniprot id: G3W7P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

9305:RUNX1
gene id: 9305:RUNX1
uniprot id: G3WPP2
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

9305:LOC100924962
gene id: 9305:LOC100924962
uniprot id: A0A7N4PRL3
names: Similarity
messages: Belongs to the UPF0461 family.

9305:HCAR1
gene id: 9305:HCAR1
uniprot id: A0A7N4UY70
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:ST8SIA3
gene id: 9305:ST8SIA3
uniprot id: A0A7N4NZ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9305:POLR2D
gene id: 9305:POLR2D
uniprot id: A0A7N4UZW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

9305:ATP5MF
gene id: 9305:ATP5MF
uniprot id: A0A7N4V4J9
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

9305:NDUFS4
gene id: 9305:NDUFS4
uniprot id: G3W7E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Mitochondrion inner membrane

9305:LOC100919984
gene id: 9305:LOC100919984
uniprot id: G3VU07
names: Similarity
messages: Belongs to the serpin family.

9305:HACD4
gene id: 9305:HACD4
uniprot id: G3WYT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:LOC100925390
gene id: 9305:LOC100925390
uniprot id: G3W948
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

9305:WDR55
gene id: 9305:WDR55
uniprot id: A0A7N4P1U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR55 family.
messages: Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis.
messages: nucleolus

9305:SERINC1
gene id: 9305:SERINC1
uniprot id: G3WKV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

9305:PEX19
gene id: 9305:PEX19
uniprot id: A0A7N4PW88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

9305:GDI2
gene id: 9305:GDI2
uniprot id: G3W4Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

9305:DOK4
gene id: 9305:DOK4
uniprot id: A0A7N4PQM6
uniprot id: G3WRV5
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

9305:LSM1
gene id: 9305:LSM1
uniprot id: A0A7N4UYC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase. LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.

9305:LOC100919379
gene id: 9305:LOC100919379
uniprot id: A0A7N4PSK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:SLC39A9
gene id: 9305:SLC39A9
uniprot id: A0A7N4NNQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: May act as a zinc-influx transporter.
messages: Membrane

9305:MPEG1
gene id: 9305:MPEG1
uniprot id: A0A7N4V194
uniprot id: G3VC57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

9305:LOC100932782
gene id: 9305:LOC100932782
uniprot id: G3WM57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LUM
gene id: 9305:LUM
uniprot id: G3VSV0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to laminin.
messages: extracellular matrix

9305:CEBPE
gene id: 9305:CEBPE
uniprot id: G3WLZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

9305:VDAC3
gene id: 9305:VDAC3
uniprot id: G3X0H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
messages: Interacts with ARMC12 in a TBC1D21-dependent manner.
messages: Mitochondrion outer membrane

9305:RDH8
gene id: 9305:RDH8
uniprot id: A0A7N4V5I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

9305:KCNE3
gene id: 9305:KCNE3
uniprot id: A0A7N4P3U3
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9305:TIGD6
gene id: 9305:TIGD6
uniprot id: A0A7N4NJG1
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100915128
gene id: 9305:LOC100915128
uniprot id: A0A7N4NLD7
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

9305:LOC100918197
gene id: 9305:LOC100918197
uniprot id: A0A7N4NXC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100931259
gene id: 9305:LOC100931259
uniprot id: A0A7N4PF23
names: Subcellular Location Annotation
messages: Nucleus

9305:GPR37
gene id: 9305:GPR37
uniprot id: A0A7N4NJ43
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:LOC100916272
gene id: 9305:LOC100916272
uniprot id: G3X337
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

9305:NCOA1
gene id: 9305:NCOA1
uniprot id: A0A7N4NS31
uniprot id: G3VKH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

9305:FAM120B
gene id: 9305:FAM120B
uniprot id: A0A7N4NYR3
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

9305:FAM163B
gene id: 9305:FAM163B
uniprot id: A0A7N4UXQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

9305:TAP2
gene id: 9305:TAP2
uniprot id: G3VDD0
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.

9305:TSPO2
gene id: 9305:TSPO2
uniprot id: G3WZS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

9305:FAM122B
gene id: 9305:FAM122B
uniprot id: G3WB29
names: Similarity
messages: Belongs to the FAM122 family.

9305:ZC3H15
gene id: 9305:ZC3H15
uniprot id: A0A7N4Q1Q3
uniprot id: G3W1U2
names: Similarity
messages: Belongs to the ZC3H15/TMA46 family.

9305:RBP2
gene id: 9305:RBP2
uniprot id: A0A7N4P1Z4
uniprot id: G3WFM8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9305:SLC6A7
gene id: 9305:SLC6A7
uniprot id: G3WY95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9305:LOC100917008
gene id: 9305:LOC100917008
uniprot id: G3WC44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:HSPA14
gene id: 9305:HSPA14
uniprot id: G3X250
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9305:IFT43
gene id: 9305:IFT43
uniprot id: A0A7N4V189
names: Similarity
messages: Belongs to the IFT43 family.

9305:LOC100926602
gene id: 9305:LOC100926602
uniprot id: G3WPT4
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

9305:CFD
gene id: 9305:CFD
uniprot id: A0A7N4V4J2
names: Function
messages: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.

9305:PMPCB
gene id: 9305:PMPCB
uniprot id: G3VDB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Mitochondrion matrix

9305:AP3B1
gene id: 9305:AP3B1
uniprot id: A0A7N4P5P0
uniprot id: G3WY03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

9305:REXO2
gene id: 9305:REXO2
uniprot id: A0A7N4NY53
names: Similarity
messages: Belongs to the oligoribonuclease family.

9305:GPR107
gene id: 9305:GPR107
uniprot id: A0A7N4NPR1
uniprot id: G3WKN0
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100915652
gene id: 9305:LOC100915652
uniprot id: A0A7N4P7P9
uniprot id: G3W2J1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Component of the 40S small ribosomal subunit.
messages: Rough endoplasmic reticulum

9305:MTFR1
gene id: 9305:MTFR1
uniprot id: A0A7N4PSC2
uniprot id: A0A7N4PYN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

9305:COLGALT2
gene id: 9305:COLGALT2
uniprot id: A0A7N4P0R8
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

9305:UBE2B
gene id: 9305:UBE2B
uniprot id: A0A7N4NNV8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9305:PPIP5K2
gene id: 9305:PPIP5K2
uniprot id: A0A7N4PS37
uniprot id: G3VEG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

9305:CUL5
gene id: 9305:CUL5
uniprot id: G3WFH2
names: Similarity
messages: Belongs to the cullin family.

9305:MRPS17
gene id: 9305:MRPS17
uniprot id: A0A7N4PB44
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

9305:TNFRSF6B
gene id: 9305:TNFRSF6B
uniprot id: A0A7N4NQ43
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100914456
gene id: 9305:LOC100914456
uniprot id: G3VK56
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:LOC100921718
gene id: 9305:LOC100921718
uniprot id: A0A7N4NZ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100923196
gene id: 9305:LOC100923196
uniprot id: G3VVI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:EXOC1
gene id: 9305:EXOC1
uniprot id: G3W5Q7
uniprot id: G3W5Q8
names: Similarity
messages: Belongs to the SEC3 family.

9305:EMP1
gene id: 9305:EMP1
uniprot id: A0A7N4P172
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

9305:DDX31
gene id: 9305:DDX31
uniprot id: G3X3H2
names: Similarity
messages: Belongs to the DEAD box helicase family.

9305:COX1
gene id: 9305:COX1
uniprot id: G1FKC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9305:RPS6KB2
gene id: 9305:RPS6KB2
uniprot id: G3VIA5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

9305:LOC100913330
gene id: 9305:LOC100913330
uniprot id: G3VWR8
names: Similarity
messages: Belongs to the peptidase C14A family.

9305:PPARD
gene id: 9305:PPARD
uniprot id: A0A7N4NN99
uniprot id: A0A7N4PLD5
uniprot id: G3WB48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9305:MLST8
gene id: 9305:MLST8
uniprot id: A0A7N4PVB7
uniprot id: G3WWQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of the mammalian target of rapamycin complex 1 (mTORC1) which contains MTOR, MLST8, RPTOR, AKT1S1/PRAS40 and DEPTOR. mTORC1 binds to and is inhibited by FKBP12-rapamycin. Part of the mammalian target of rapamycin complex 2 (mTORC2) which contains MTOR, MLST8, PRR5, RICTOR, MAPKAP1 and DEPTOR. Contrary to mTORC1, mTORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Interacts directly with MTOR and RPTOR. Interacts with RHEB. Interacts with MEAK7. Interacts with SIK3.
messages: Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1, which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1, LST8 interacts directly with MTOR and enhances its kinase activity. In nutrient-poor conditions, stabilizes the MTOR-RPTOR interaction and favors RPTOR-mediated inhibition of MTOR activity. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1. mTORC2 also modulates the phosphorylation of PRKCA.

9305:ADRA1A
gene id: 9305:ADRA1A
uniprot id: A0A7N4PLC2
uniprot id: G3VTI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: caveola

9305:SLC25A4
gene id: 9305:SLC25A4
uniprot id: A0A7N4PK42
uniprot id: G3VCY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

9305:TMEM178B
gene id: 9305:TMEM178B
uniprot id: A0A7N4PAW9
names: Similarity
messages: Belongs to the TMEM178 family.

9305:TNFAIP6
gene id: 9305:TNFAIP6
uniprot id: A0A7N4V578
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:TSHB
gene id: 9305:TSHB
uniprot id: G3WD21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9305:LLPH
gene id: 9305:LLPH
uniprot id: A0A7N4PT62
names: Similarity
messages: Belongs to the learning-associated protein family.

9305:GPD2
gene id: 9305:GPD2
uniprot id: G3WLA1
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

9305:CALHM5
gene id: 9305:CALHM5
uniprot id: A0A7N4V576
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9305:EFNB3
gene id: 9305:EFNB3
uniprot id: G3WRN7
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:GALK2
gene id: 9305:GALK2
uniprot id: A0A7N4NVB4
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

9305:LOC105750536
gene id: 9305:LOC105750536
uniprot id: G3WLV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9305:SLC2A6
gene id: 9305:SLC2A6
uniprot id: G3VXJ7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

9305:SAT1
gene id: 9305:SAT1
uniprot id: G3W771
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

9305:CSRNP3
gene id: 9305:CSRNP3
uniprot id: A0A7N4NK67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

9305:LOC100924781
gene id: 9305:LOC100924781
uniprot id: A0A7N4NXB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CCN5
gene id: 9305:CCN5
uniprot id: G3W7V5
names: Similarity
messages: Belongs to the CCN family.

9305:GALNT3
gene id: 9305:GALNT3
uniprot id: A0A7N4NJA3
uniprot id: G3WC12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9305:STAR
gene id: 9305:STAR
uniprot id: G3WXW3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

9305:BZW1
gene id: 9305:BZW1
uniprot id: A0A7N4PVW0
names: Similarity
messages: Belongs to the BZW family.

9305:LOC100934546
gene id: 9305:LOC100934546
uniprot id: A0A7N4NPP9
names: Subcellular Location Annotation
messages: Membrane

9305:INSL3
gene id: 9305:INSL3
uniprot id: A0A7N4NW71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted
messages: Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.

9305:LOC100921885
gene id: 9305:LOC100921885
uniprot id: A0A7N4NPZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:DHRS7C
gene id: 9305:DHRS7C
uniprot id: G3VGD9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9305:S100Z
gene id: 9305:S100Z
uniprot id: A0A7N4NPU4
names: Similarity
messages: Belongs to the S-100 family.

9305:LOC100930070
gene id: 9305:LOC100930070
uniprot id: G3VFQ9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

9305:MMP14
gene id: 9305:MMP14
uniprot id: G3WH26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Cytoplasm
messages: Melanosome

9305:LOC100913808
gene id: 9305:LOC100913808
uniprot id: G3W4B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TRAPPC3L
gene id: 9305:TRAPPC3L
uniprot id: G3VTI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

9305:EED
gene id: 9305:EED
uniprot id: G3WKF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ESC family.
messages: Nucleus

9305:CPSF2
gene id: 9305:CPSF2
uniprot id: G3W9U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

9305:DMGDH
gene id: 9305:DMGDH
uniprot id: G3WQF5
names: Similarity
messages: Belongs to the GcvT family.

9305:EPHA1
gene id: 9305:EPHA1
uniprot id: G3VXD9
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100930478
gene id: 9305:LOC100930478
uniprot id: G3W8B8
names: Similarity
messages: Belongs to the hexokinase family.

9305:MEF2A
gene id: 9305:MEF2A
uniprot id: A0A7N4PJT8
uniprot id: G3WX77
names: Subcellular Location Annotation
messages: Nucleus

9305:GNPAT
gene id: 9305:GNPAT
uniprot id: A0A7N4UXZ8
uniprot id: G3X284
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Peroxisome membrane

9305:C3H2orf49
gene id: 9305:C3H2orf49
uniprot id: G3X218
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

9305:CSTB
gene id: 9305:CSTB
uniprot id: A0A7N4V3D9
names: Similarity
messages: Belongs to the cystatin family.

9305:LOC100932860
gene id: 9305:LOC100932860
uniprot id: G3VIT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

9305:IGFBP1
gene id: 9305:IGFBP1
uniprot id: G3VK90
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:NFU1
gene id: 9305:NFU1
uniprot id: A0A7N4PCW8
names: Similarity
messages: Belongs to the NifU family.

9305:ENTPD5
gene id: 9305:ENTPD5
uniprot id: A0A7N4PFK5
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9305:SSTR2
gene id: 9305:SSTR2
uniprot id: A0A7N4NS85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

9305:SGPL1
gene id: 9305:SGPL1
uniprot id: G3W3D1
names: Similarity
messages: Belongs to the group II decarboxylase family.

9305:EDA2R
gene id: 9305:EDA2R
uniprot id: G3W2V0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:SH2B1
gene id: 9305:SH2B1
uniprot id: G3WFN7
names: Similarity
messages: Belongs to the SH2B adapter family.

9305:CKAP2
gene id: 9305:CKAP2
uniprot id: G3W865
names: Similarity
messages: Belongs to the CKAP2 family.

9305:LOC100923001
gene id: 9305:LOC100923001
uniprot id: G3VEE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:KCND2
gene id: 9305:KCND2
uniprot id: G3VYU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.2/KCND2 sub-subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite
messages: dendritic spine

9305:RC3H2
gene id: 9305:RC3H2
uniprot id: A0A7N4NJR8
uniprot id: G3VZP9
names: Subcellular Location Annotation
messages: P-body

9305:ZDHHC6
gene id: 9305:ZDHHC6
uniprot id: A0A7N4NZ04
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9305:LOC100924488
gene id: 9305:LOC100924488
uniprot id: G3VXC8
names: Similarity
messages: Belongs to the intermediate filament family.

9305:F13B
gene id: 9305:F13B
uniprot id: G3VDY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100918637
gene id: 9305:LOC100918637
uniprot id: A0A7N4PIK3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:PRKAR1B
gene id: 9305:PRKAR1B
uniprot id: G3WA11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

9305:LOC100928280
gene id: 9305:LOC100928280
uniprot id: G3VTI3
uniprot id: G3W1M2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

9305:SCD
gene id: 9305:SCD
uniprot id: G3VF96
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

9305:GPC3
gene id: 9305:GPC3
uniprot id: G3VD75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

9305:LOC100928083
gene id: 9305:LOC100928083
uniprot id: A0A7N4V0S2
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

9305:LOC100933077
gene id: 9305:LOC100933077
uniprot id: G3WRS6
names: Similarity
messages: Belongs to the intermediate filament family.

9305:ELF5
gene id: 9305:ELF5
uniprot id: A0A7N4PW60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9305:MYB
gene id: 9305:MYB
uniprot id: A0A7N4P7K7
uniprot id: G3WPH4
names: Subcellular Location Annotation
messages: Nucleus

9305:ACVR2A
gene id: 9305:ACVR2A
uniprot id: G3W8S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9305:ISM2
gene id: 9305:ISM2
uniprot id: A0A7N4NZ65
names: Similarity
messages: Belongs to the isthmin family.

9305:CCN2
gene id: 9305:CCN2
uniprot id: G3WBU2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:ST3GAL1
gene id: 9305:ST3GAL1
uniprot id: A0A7N4NWK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9305:SARS1
gene id: 9305:SARS1
uniprot id: G3X052
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

9305:MNS1
gene id: 9305:MNS1
uniprot id: G3WZM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

9305:FITM1
gene id: 9305:FITM1
uniprot id: A0A7N4PTN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. FIT1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays an important role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. Directly binds to diacylglycerol (DAGs) and triacylglycerol.

9305:DCLRE1C
gene id: 9305:DCLRE1C
uniprot id: G3X2C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

9305:LOC100919937
gene id: 9305:LOC100919937
uniprot id: G3VMQ5
names: Subcellular Location Annotation
messages: Membrane

9305:FAXC
gene id: 9305:FAXC
uniprot id: A0A7N4P8D3
names: Similarity
messages: Belongs to the FAX family.

9305:LOC100924139
gene id: 9305:LOC100924139
uniprot id: G3W6G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CRHBP
gene id: 9305:CRHBP
uniprot id: G3VXK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

9305:PSMA8
gene id: 9305:PSMA8
uniprot id: G3WX18
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9305:SEPTIN11
gene id: 9305:SEPTIN11
uniprot id: A0A7N4NT70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9305:TMEM126A
gene id: 9305:TMEM126A
uniprot id: A0A7N4NZG5
names: Subcellular Location Annotation
messages: Membrane

9305:COPS7A
gene id: 9305:COPS7A
uniprot id: G3WS15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

9305:MRPL43
gene id: 9305:MRPL43
uniprot id: A0A7N4NPN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

9305:MFSD6
gene id: 9305:MFSD6
uniprot id: G3WRF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

9305:BTD
gene id: 9305:BTD
uniprot id: A0A7N4P1G9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

9305:LOC100927348
gene id: 9305:LOC100927348
uniprot id: A0A7N4NT30
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9305:LOC100930597
gene id: 9305:LOC100930597
uniprot id: A0A7N4PIW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:GUK1
gene id: 9305:GUK1
uniprot id: A0A7N4PAU1
names: Similarity
messages: Belongs to the guanylate kinase family.

9305:PKN1
gene id: 9305:PKN1
uniprot id: A0A7N4NXY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

9305:HSD17B2
gene id: 9305:HSD17B2
uniprot id: A0A7N4NGI3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9305:METTL6
gene id: 9305:METTL6
uniprot id: G3VW57
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

9305:WASHC3
gene id: 9305:WASHC3
uniprot id: G3VIX2
names: Similarity
messages: Belongs to the CCDC53 family.

9305:TSPAN11
gene id: 9305:TSPAN11
uniprot id: A0A7N4PIT4
uniprot id: G3WA04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9305:LOC100921604
gene id: 9305:LOC100921604
uniprot id: A0A7N4PUS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100917673
gene id: 9305:LOC100917673
uniprot id: G3VVI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TMEM38A
gene id: 9305:TMEM38A
uniprot id: A0A7N4PNG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

9305:ZCCHC4
gene id: 9305:ZCCHC4
uniprot id: G3VPG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC4 family.
messages: Cytoplasm
messages: nucleolus

9305:LOC100922300
gene id: 9305:LOC100922300
uniprot id: G3VGK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:EVA1C
gene id: 9305:EVA1C
uniprot id: G3VEV1
names: Similarity
messages: Belongs to the EVA1 family.

9305:LOC100916591
gene id: 9305:LOC100916591
uniprot id: A0A7N4NVN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex).
messages: Belongs to the UQCC3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.

9305:LOC100934553
gene id: 9305:LOC100934553
uniprot id: G3WZP4
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:SPO11
gene id: 9305:SPO11
uniprot id: G3VC58
names: Similarity
messages: Belongs to the TOP6A family.

9305:LMOD2
gene id: 9305:LMOD2
uniprot id: G3W7C1
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

9305:FGR
gene id: 9305:FGR
uniprot id: G3VEY1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9305:FGFBP2
gene id: 9305:FGFBP2
uniprot id: G3X269
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

9305:IFRD2
gene id: 9305:IFRD2
uniprot id: A0A7N4V1L5
names: Similarity
messages: Belongs to the IFRD family.

9305:MTERF2
gene id: 9305:MTERF2
uniprot id: A0A7N4NQY9
names: Similarity
messages: Belongs to the mTERF family.

9305:FMNL2
gene id: 9305:FMNL2
uniprot id: A0A7N4PFZ3
uniprot id: G3VRC4
names: Similarity
messages: Belongs to the formin homology family.

9305:PLBD1
gene id: 9305:PLBD1
uniprot id: G3WYC5
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

9305:ATPSCKMT
gene id: 9305:ATPSCKMT
uniprot id: A0A7N4NW72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

9305:DCPS
gene id: 9305:DCPS
uniprot id: G3VH86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HIT family.
messages: Cytoplasm
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.
messages: Nucleus

9305:TMEM218
gene id: 9305:TMEM218
uniprot id: A0A7N4NMM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

9305:BROX
gene id: 9305:BROX
uniprot id: A0A7N4V7B9
uniprot id: G3W5N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BROX family.
messages: Membrane

9305:NIFK
gene id: 9305:NIFK
uniprot id: G3WED0
names: Subcellular Location Annotation
messages: nucleolus

9305:SATB1
gene id: 9305:SATB1
uniprot id: G3WRP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

9305:LOC100924624
gene id: 9305:LOC100924624
uniprot id: G3VQH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CDH18
gene id: 9305:CDH18
uniprot id: G3VZE2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9305:FBLN5
gene id: 9305:FBLN5
uniprot id: A0A7N4NPS9
uniprot id: G3W1X0
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:UBL3
gene id: 9305:UBL3
uniprot id: A0A7N4V0Q2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:POMC
gene id: 9305:POMC
uniprot id: A0A7N4NUF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes.
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Endogenous orexigenic opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

9305:SNF8
gene id: 9305:SNF8
uniprot id: G3WLY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

9305:STARD6
gene id: 9305:STARD6
uniprot id: A0A7N4P2E6
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

9305:SNAP47
gene id: 9305:SNAP47
uniprot id: A0A7N4PZH1
uniprot id: G3W5G0
names: Similarity
messages: Belongs to the SVAP1 family.

9305:LOC100928980
gene id: 9305:LOC100928980
uniprot id: G3VLK2
names: Similarity
messages: Belongs to the intermediate filament family.

9305:ACP1
gene id: 9305:ACP1
uniprot id: A0A7N4PJN3
uniprot id: G3VS31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

9305:LOC100913481
gene id: 9305:LOC100913481
uniprot id: A0A7N4PB35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Membrane
messages: Mitochondrion inner membrane

9305:TAF7L
gene id: 9305:TAF7L
uniprot id: A0A7N4PA98
uniprot id: G3WL50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

9305:EFEMP1
gene id: 9305:EFEMP1
uniprot id: G3WI99
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:MAT2B
gene id: 9305:MAT2B
uniprot id: A0A7N4NK77
uniprot id: G3W100
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

9305:NCOA7
gene id: 9305:NCOA7
uniprot id: A0A7N4PDT7
uniprot id: G3WW09
names: Similarity
messages: Belongs to the OXR1 family.

9305:MRPS23
gene id: 9305:MRPS23
uniprot id: G3VWQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Mitochondrion

9305:ASF1B
gene id: 9305:ASF1B
uniprot id: G3W518
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

9305:CASP10
gene id: 9305:CASP10
uniprot id: A0A7N4V6N5
names: Similarity
messages: Belongs to the peptidase C14A family.

9305:LOC100917414
gene id: 9305:LOC100917414
uniprot id: G3VUF8
names: Subcellular Location Annotation
messages: Membrane

9305:LETM1
gene id: 9305:LETM1
uniprot id: G3W3Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LETM1 family.
messages: Membrane
messages: Mitochondrion inner membrane

9305:CD55
gene id: 9305:CD55
uniprot id: A0A7N4NFP9
uniprot id: G3X2Y3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:CAPN1
gene id: 9305:CAPN1
uniprot id: G3VKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C2 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9305:DUSP27
gene id: 9305:DUSP27
uniprot id: G3X249
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9305:LOC100928205
gene id: 9305:LOC100928205
uniprot id: G3VW86
names: Similarity
messages: Belongs to the intermediate filament family.

9305:SEC22C
gene id: 9305:SEC22C
uniprot id: G3W5T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

9305:ATP6V1B2
gene id: 9305:ATP6V1B2
uniprot id: G3WA14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

9305:AKAP5
gene id: 9305:AKAP5
uniprot id: A0A7N4NNJ7
names: Subcellular Location Annotation
messages: Membrane

9305:ERGIC1
gene id: 9305:ERGIC1
uniprot id: G3VPI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

9305:TBC1D7
gene id: 9305:TBC1D7
uniprot id: G3W592
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

9305:ADAMDEC1
gene id: 9305:ADAMDEC1
uniprot id: G3WF19
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:JPH1
gene id: 9305:JPH1
uniprot id: G3VWL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

9305:SLC12A9
gene id: 9305:SLC12A9
uniprot id: A0A7N4V1X4
uniprot id: G3VZW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

9305:LOC100926719
gene id: 9305:LOC100926719
uniprot id: A0A7N4NR34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRAME family. LRRC14 subfamily.
messages: Cytoplasm

9305:CCN1
gene id: 9305:CCN1
uniprot id: G3WHV5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:CDADC1
gene id: 9305:CDADC1
uniprot id: G3W657
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

9305:TFCP2L1
gene id: 9305:TFCP2L1
uniprot id: G3WLK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

9305:CCR10
gene id: 9305:CCR10
uniprot id: G3WKR2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:LOC100915501
gene id: 9305:LOC100915501
uniprot id: G3WTT6
names: Subcellular Location Annotation
messages: Membrane

9305:ANKRD34B
gene id: 9305:ANKRD34B
uniprot id: A0A7N4V4X9
names: Similarity
messages: Belongs to the ANKRD34 family.

9305:RPRM
gene id: 9305:RPRM
uniprot id: A0A7N4PWD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reprimo family.
messages: Cytoplasm
messages: Membrane

9305:TMEM163
gene id: 9305:TMEM163
uniprot id: G3WMI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: May bind zinc and other divalent cations and recruit them to vesicular organelles.
messages: Membrane
messages: synaptic vesicle membrane

9305:KIF18B
gene id: 9305:KIF18B
uniprot id: G3W437
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9305:LOC100916127
gene id: 9305:LOC100916127
uniprot id: G3WUW9
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:CLTRN
gene id: 9305:CLTRN
uniprot id: G3WLD7
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100915272
gene id: 9305:LOC100915272
uniprot id: G3VCN9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9305:MED21
gene id: 9305:MED21
uniprot id: A0A7N4PDF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

9305:DDX18
gene id: 9305:DDX18
uniprot id: G3X3E5
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.

9305:WNT3
gene id: 9305:WNT3
uniprot id: G3WLF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9305:TMEM45A
gene id: 9305:TMEM45A
uniprot id: G3VP58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9305:TPX2
gene id: 9305:TPX2
uniprot id: G3WJN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

9305:LOC100920242
gene id: 9305:LOC100920242
uniprot id: G3VI21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100915323
gene id: 9305:LOC100915323
uniprot id: A0A7N4PZJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100922672
gene id: 9305:LOC100922672
uniprot id: G3VQ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ICOS
gene id: 9305:ICOS
uniprot id: A0A7N4PM64
uniprot id: G3WT94
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
messages: Homodimer; disulfide-linked.
messages: Membrane

9305:ANAPC10
gene id: 9305:ANAPC10
uniprot id: A0A7N4PM23
uniprot id: G3W7S3
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

9305:GLYATL3
gene id: 9305:GLYATL3
uniprot id: G3VNU7
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

9305:LOC100920753
gene id: 9305:LOC100920753
uniprot id: G3VI12
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

9305:LYPLAL1
gene id: 9305:LYPLAL1
uniprot id: A0A7N4Q1F2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

9305:CAPN3
gene id: 9305:CAPN3
uniprot id: G3VZS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

9305:SLC26A1
gene id: 9305:SLC26A1
uniprot id: G3WPW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate.
messages: Membrane

9305:CXCL13
gene id: 9305:CXCL13
uniprot id: A0A7N4NWD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9305:ATP6
gene id: 9305:ATP6
uniprot id: G1FKC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

9305:FAM102A
gene id: 9305:FAM102A
uniprot id: A0A7N4NJ14
names: Similarity
messages: Belongs to the FAM102 family.

9305:LOC100933477
gene id: 9305:LOC100933477
uniprot id: G3VL95
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9305:TENT5C
gene id: 9305:TENT5C
uniprot id: A0A7N4NHB9
uniprot id: G3VVB6
names: Similarity
messages: Belongs to the TENT family.
messages: Belongs to the glycosyl hydrolase 47 family.

9305:PTAFR
gene id: 9305:PTAFR
uniprot id: A0A7N4NGT6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

9305:GABRA4
gene id: 9305:GABRA4
uniprot id: G3W8H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9305:LOC100923826
gene id: 9305:LOC100923826
uniprot id: G3VPD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion inner membrane

9305:ORM1
gene id: 9305:ORM1
uniprot id: A0A7N4V0E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

9305:FOXI1
gene id: 9305:FOXI1
uniprot id: G3X2P6
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100915842
gene id: 9305:LOC100915842
uniprot id: A0A7N4PUU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PLD2
gene id: 9305:PLD2
uniprot id: G3VJE2
names: Similarity
messages: Belongs to the phospholipase D family.

9305:TAAR5
gene id: 9305:TAAR5
uniprot id: G3VUD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9305:SLC7A11
gene id: 9305:SLC7A11
uniprot id: G3WGE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

9305:PLIN3
gene id: 9305:PLIN3
uniprot id: A0A7N4PA51
names: Similarity
messages: Belongs to the perilipin family.

9305:SLC5A6
gene id: 9305:SLC5A6
uniprot id: G3WGU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9305:CFAP206
gene id: 9305:CFAP206
uniprot id: A0A7N4Q0V8
uniprot id: G3W7I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP206 family.
messages: cilium axoneme
messages: cilium basal body

9305:CNTF
gene id: 9305:CNTF
uniprot id: A0A7N4P4Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

9305:PCYT1B
gene id: 9305:PCYT1B
uniprot id: A0A7N4Q0R5
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

9305:SPG7
gene id: 9305:SPG7
uniprot id: G3WS00
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

9305:CHRM2
gene id: 9305:CHRM2
uniprot id: G3VX75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

9305:TMCO3
gene id: 9305:TMCO3
uniprot id: G3WT35
names: Subcellular Location Annotation
messages: Membrane

9305:KCNAB3
gene id: 9305:KCNAB3
uniprot id: A0A7N4NUH1
uniprot id: A0A7N4PF26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cytoplasm

9305:LOC100918111
gene id: 9305:LOC100918111
uniprot id: G3W4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:HAL
gene id: 9305:HAL
uniprot id: A0A7N4UY41
uniprot id: G3WHS2
names: Similarity
messages: Belongs to the PAL/histidase family.

9305:GASK1B
gene id: 9305:GASK1B
uniprot id: G3WRS9
names: Similarity
messages: Belongs to the GASK family.

9305:FAM210A
gene id: 9305:FAM210A
uniprot id: A0A7N4PZ51
names: Similarity
messages: Belongs to the FAM210 family.

9305:LOC100918039
gene id: 9305:LOC100918039
uniprot id: G3W9G4
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

9305:TEX10
gene id: 9305:TEX10
uniprot id: G3W910
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

9305:NR2C1
gene id: 9305:NR2C1
uniprot id: G3VMA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9305:KIF23
gene id: 9305:KIF23
uniprot id: A0A7N4PYD1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9305:LOC100919276
gene id: 9305:LOC100919276
uniprot id: A0A7N4NKZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100929673
gene id: 9305:LOC100929673
uniprot id: A0A7N4V0A1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9305:ATP5PO
gene id: 9305:ATP5PO
uniprot id: G3VBA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

9305:LOC100920453
gene id: 9305:LOC100920453
uniprot id: G3WZU8
names: Similarity
messages: Belongs to the GroES chaperonin family.

9305:RBKS
gene id: 9305:RBKS
uniprot id: A0A7N4UZ42
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

9305:PLPBP
gene id: 9305:PLPBP
uniprot id: A0A7N4NFG9
uniprot id: G3WVA8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

9305:CAV1
gene id: 9305:CAV1
uniprot id: A0A7N4PUT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: Membrane raft
messages: caveola

9305:PDGFD
gene id: 9305:PDGFD
uniprot id: A0A7N4V4P0
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Homodimer; disulfide-linked. Interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:RAB27B
gene id: 9305:RAB27B
uniprot id: G3WXN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

9305:SLC39A12
gene id: 9305:SLC39A12
uniprot id: G3WED6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

9305:KCNG3
gene id: 9305:KCNG3
uniprot id: A0A7N4V6R8
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100922659
gene id: 9305:LOC100922659
uniprot id: G3VNX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9305:HRH3
gene id: 9305:HRH3
uniprot id: A0A7N4PPQ2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:VWC2L
gene id: 9305:VWC2L
uniprot id: G3WP94
names: Subcellular Location Annotation
messages: Synapse

9305:NPRL3
gene id: 9305:NPRL3
uniprot id: A0A7N4V759
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
messages: Belongs to the NPR3 family.
messages: Lysosome

9305:CBY2
gene id: 9305:CBY2
uniprot id: G3W232
names: Similarity
names: Subunit
messages: Belongs to the chibby family. SPERT subfamily.
messages: Homodimer. Binds to NEK1.

9305:TELO2
gene id: 9305:TELO2
uniprot id: G3WA99
names: Similarity
messages: Belongs to the TEL2 family.

9305:LOC100921734
gene id: 9305:LOC100921734
uniprot id: A0A7N4PGF0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:NDC80
gene id: 9305:NDC80
uniprot id: A0A7N4PMV7
uniprot id: G3VCQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

9305:PHTF1
gene id: 9305:PHTF1
uniprot id: G3WEV3
uniprot id: G3WEV4
names: Subcellular Location Annotation
messages: Membrane

9305:CCNH
gene id: 9305:CCNH
uniprot id: G3WWE0
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

9305:LOC100925341
gene id: 9305:LOC100925341
uniprot id: G3VLK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

9305:AQP2
gene id: 9305:AQP2
uniprot id: A0A7N4NNI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

9305:LOC105749869
gene id: 9305:LOC105749869
uniprot id: G3W529
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100915003
gene id: 9305:LOC100915003
uniprot id: G3VAJ0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

9305:LOC100930036
gene id: 9305:LOC100930036
uniprot id: A0A7N4NY84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:NDUFAB1
gene id: 9305:NDUFAB1
uniprot id: G3W5X1
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

9305:HSPA5
gene id: 9305:HSPA5
uniprot id: A0A7N4PLT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

9305:B3GALT1
gene id: 9305:B3GALT1
uniprot id: A0A7N4V5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:SLC43A1
gene id: 9305:SLC43A1
uniprot id: G3WR82
uniprot id: G3WR83
names: Subcellular Location Annotation
messages: Membrane

9305:SLC30A4
gene id: 9305:SLC30A4
uniprot id: A0A7N4NFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9305:CDC42EP4
gene id: 9305:CDC42EP4
uniprot id: G3WSC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

9305:PPM1B
gene id: 9305:PPM1B
uniprot id: A0A7N4P668
uniprot id: G3X2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

9305:F2RL3
gene id: 9305:F2RL3
uniprot id: G3VUX6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:TIGD4
gene id: 9305:TIGD4
uniprot id: G3W0T3
names: Subcellular Location Annotation
messages: Nucleus

9305:GUCY1A1
gene id: 9305:GUCY1A1
uniprot id: A0A7N4PL11
uniprot id: G3VPS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

9305:QPCT
gene id: 9305:QPCT
uniprot id: G3W588
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

9305:LOC100924274
gene id: 9305:LOC100924274
uniprot id: G3VF77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:SSTR1
gene id: 9305:SSTR1
uniprot id: G3VL76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CD5
gene id: 9305:CD5
uniprot id: G3WAW6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:TMEM135
gene id: 9305:TMEM135
uniprot id: G3VRF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM135 family.
messages: Membrane
messages: Peroxisome membrane

9305:SLBP
gene id: 9305:SLBP
uniprot id: A0A7N4NKA5
names: Similarity
messages: Belongs to the SLBP family.

9305:CFAP126
gene id: 9305:CFAP126
uniprot id: G3WX54
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the Flattop family.

9305:GDAP1
gene id: 9305:GDAP1
uniprot id: A0A7N4PQM9
names: Similarity
messages: Belongs to the GST superfamily.

9305:CD163
gene id: 9305:CD163
uniprot id: G3VJT8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:SLC26A9
gene id: 9305:SLC26A9
uniprot id: G3WVG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport.
messages: Membrane

9305:CACNG3
gene id: 9305:CACNG3
uniprot id: A0A7N4UZX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

9305:SLC46A3
gene id: 9305:SLC46A3
uniprot id: G3X2H1
names: Subcellular Location Annotation
messages: Membrane

9305:GNAQ
gene id: 9305:GNAQ
uniprot id: G3W7B2
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

9305:STXBP3
gene id: 9305:STXBP3
uniprot id: G3WXV5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

9305:TPP1
gene id: 9305:TPP1
uniprot id: A0A7N4NSG9
uniprot id: G3W6M3
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

9305:DLGAP1
gene id: 9305:DLGAP1
uniprot id: A0A7N4NUN7
uniprot id: G3WF58
names: Similarity
messages: Belongs to the SAPAP family.

9305:LOC100926690
gene id: 9305:LOC100926690
uniprot id: G3WEG3
names: Subcellular Location Annotation
messages: Membrane

9305:ARRDC1
gene id: 9305:ARRDC1
uniprot id: G3WGP9
names: Similarity
messages: Belongs to the arrestin family.

9305:LOC100919222
gene id: 9305:LOC100919222
uniprot id: G3WEY5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9305:NCOA3
gene id: 9305:NCOA3
uniprot id: A0A7N4NUL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

9305:LOC100935364
gene id: 9305:LOC100935364
uniprot id: G3WCM8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:UTS2R
gene id: 9305:UTS2R
uniprot id: A0A7N4PJ67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

9305:STX7
gene id: 9305:STX7
uniprot id: G3WNI0
names: Similarity
messages: Belongs to the syntaxin family.

9305:PAPPA2
gene id: 9305:PAPPA2
uniprot id: G3W214
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:CD244
gene id: 9305:CD244
uniprot id: A0A7N4V2S3
uniprot id: G3VKD5
names: Subcellular Location Annotation
messages: Membrane

9305:RPS6KA5
gene id: 9305:RPS6KA5
uniprot id: G3WLS5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

9305:KCNB1
gene id: 9305:KCNB1
uniprot id: G3VVR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: sarcolemma
messages: synaptosome

9305:MRPS18C
gene id: 9305:MRPS18C
uniprot id: G3VYC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Mitochondrion

9305:ACAA2
gene id: 9305:ACAA2
uniprot id: G3VDY7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

9305:LOC100935001
gene id: 9305:LOC100935001
uniprot id: G3VS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100918395
gene id: 9305:LOC100918395
uniprot id: A0A7N4PGP2
names: Similarity
messages: Belongs to the SCO1/2 family.

9305:SLITRK5
gene id: 9305:SLITRK5
uniprot id: G3W5F4
names: Similarity
messages: Belongs to the SLITRK family.

9305:DDX59
gene id: 9305:DDX59
uniprot id: G3WPP1
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

9305:ARL2
gene id: 9305:ARL2
uniprot id: G3VKZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

9305:PGF
gene id: 9305:PGF
uniprot id: A0A7N4PZP4
uniprot id: G3X1B7
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

9305:LMNB1
gene id: 9305:LMNB1
uniprot id: G3WGG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

9305:FAM214B
gene id: 9305:FAM214B
uniprot id: G3WVR4
names: Similarity
messages: Belongs to the FAM214 family.

9305:TTYH2
gene id: 9305:TTYH2
uniprot id: G3W0G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

9305:GPR15
gene id: 9305:GPR15
uniprot id: G3VH89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:THEMIS2
gene id: 9305:THEMIS2
uniprot id: G3WQW9
names: Similarity
messages: Belongs to the themis family.

9305:EIF4E1B
gene id: 9305:EIF4E1B
uniprot id: G3W0X3
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

9305:NKX2-1
gene id: 9305:NKX2-1
uniprot id: G3W6D0
names: Subcellular Location Annotation
messages: Nucleus

9305:MINDY1
gene id: 9305:MINDY1
uniprot id: A0A7N4P4S6
uniprot id: G3WIN0
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

9305:TMEM39A
gene id: 9305:TMEM39A
uniprot id: A0A7N4PTK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

9305:SMPDL3A
gene id: 9305:SMPDL3A
uniprot id: G3VLN6
uniprot id: G3VLN7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

9305:NPR3
gene id: 9305:NPR3
uniprot id: G3WCY7
names: Subcellular Location Annotation
messages: Membrane

9305:FGF7
gene id: 9305:FGF7
uniprot id: A0A7N4PTF8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9305:GPRC5C
gene id: 9305:GPRC5C
uniprot id: G3VJE9
uniprot id: G3VJF0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:SHROOM3
gene id: 9305:SHROOM3
uniprot id: G3W3K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

9305:LOC100921866
gene id: 9305:LOC100921866
uniprot id: A0A7N4PWE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TFB2M
gene id: 9305:TFB2M
uniprot id: G3W8D9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

9305:TFAP2C
gene id: 9305:TFAP2C
uniprot id: G3WDQ5
names: Similarity
messages: Belongs to the AP-2 family.

9305:DIS3L
gene id: 9305:DIS3L
uniprot id: G3WBL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNR ribonuclease family.
messages: Component of the RNA exosome complex. The catalytically inactive RNA exosome core (Exo-9) complex is believed to associate with catalytic subunits EXOSC10, and DIS3 or DIS3L in cytoplasmic- and nuclear-specific RNA exosome complex forms.
messages: Cytoplasm
messages: Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.

9305:CLVS2
gene id: 9305:CLVS2
uniprot id: A0A7N4P9C9
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

9305:ALDH3A1
gene id: 9305:ALDH3A1
uniprot id: G3VSU8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9305:ENO3
gene id: 9305:ENO3
uniprot id: G3VUH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

9305:LOC100913627
gene id: 9305:LOC100913627
uniprot id: G3WPB5
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

9305:GHITM
gene id: 9305:GHITM
uniprot id: G3VX05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9305:RAPSN
gene id: 9305:RAPSN
uniprot id: G3WYM7
names: Similarity
messages: Belongs to the RAPsyn family.

9305:RSPO2
gene id: 9305:RSPO2
uniprot id: G3WC93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

9305:LPAR5
gene id: 9305:LPAR5
uniprot id: G3WR60
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:NUP35
gene id: 9305:NUP35
uniprot id: A0A7N4PIW3
uniprot id: G3W7C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

9305:OPN4
gene id: 9305:OPN4
uniprot id: G3W2U2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:PLRG1
gene id: 9305:PLRG1
uniprot id: G3WN54
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

9305:TMEM161B
gene id: 9305:TMEM161B
uniprot id: A0A7N4PTI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

9305:ENTPD7
gene id: 9305:ENTPD7
uniprot id: A0A7N4PWM0
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9305:CIAO2B
gene id: 9305:CIAO2B
uniprot id: A0A7N4NGD7
names: Similarity
messages: Belongs to the MIP18 family.

9305:LOC100925903
gene id: 9305:LOC100925903
uniprot id: G3VW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PLXNA4
gene id: 9305:PLXNA4
uniprot id: G3WT00
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:LPAR3
gene id: 9305:LPAR3
uniprot id: G3WUP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TTC21B
gene id: 9305:TTC21B
uniprot id: G3WF32
names: Similarity
messages: Belongs to the TTC21 family.

9305:TAF13
gene id: 9305:TAF13
uniprot id: G3WZF1
names: Subcellular Location Annotation
messages: Nucleus

9305:DOK5
gene id: 9305:DOK5
uniprot id: G3W4P5
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

9305:POLR2C
gene id: 9305:POLR2C
uniprot id: A0A7N4NM46
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

9305:HOXB1
gene id: 9305:HOXB1
uniprot id: G3WFK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

9305:LOC100919979
gene id: 9305:LOC100919979
uniprot id: A0A7N4NPZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LAMTOR3
gene id: 9305:LAMTOR3
uniprot id: A0A7N4PYL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
messages: Belongs to the LAMTOR3 family.
messages: Endosome membrane
messages: Late endosome membrane

9305:RBM8A
gene id: 9305:RBM8A
uniprot id: G3X2V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

9305:LOC100931640
gene id: 9305:LOC100931640
uniprot id: A0A7N4V2F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:GRM3
gene id: 9305:GRM3
uniprot id: G3X3G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

9305:TMEM182
gene id: 9305:TMEM182
uniprot id: A0A7N4NYS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

9305:RAD52
gene id: 9305:RAD52
uniprot id: G3VQX1
uniprot id: G3VQX2
names: Similarity
messages: Belongs to the RAD52 family.

9305:LOC100928456
gene id: 9305:LOC100928456
uniprot id: G3VIU9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9305:HEXIM1
gene id: 9305:HEXIM1
uniprot id: A0A7N4V2E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

9305:CROT
gene id: 9305:CROT
uniprot id: A0A7N4PBK0
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

9305:DUT
gene id: 9305:DUT
uniprot id: A0A7N4PQC6
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

9305:GPR157
gene id: 9305:GPR157
uniprot id: A0A7N4NQ56
names: Subcellular Location Annotation
messages: Membrane

9305:C1H12orf65
gene id: 9305:C1H12orf65
uniprot id: A0A7N4PQ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

9305:CREB1
gene id: 9305:CREB1
uniprot id: A0A7N4UYD2
uniprot id: G3WLN6
names: Subcellular Location Annotation
messages: Nucleus

9305:TOM1L1
gene id: 9305:TOM1L1
uniprot id: A0A7N4P833
uniprot id: G3WVN8
names: Similarity
messages: Belongs to the TOM1 family.

9305:TMEM50B
gene id: 9305:TMEM50B
uniprot id: A0A7N4PGB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

9305:LOC100918656
gene id: 9305:LOC100918656
uniprot id: A0A7N4NT56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:GBA2
gene id: 9305:GBA2
uniprot id: G3WMQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

9305:LOC100916721
gene id: 9305:LOC100916721
uniprot id: G5EA65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9305:RPL22L1
gene id: 9305:RPL22L1
uniprot id: A0A7N4UZN1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

9305:AZIN1
gene id: 9305:AZIN1
uniprot id: G3X2J1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9305:SPSB3
gene id: 9305:SPSB3
uniprot id: G3WJU3
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

9305:LOC100926477
gene id: 9305:LOC100926477
uniprot id: G3VAY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9305:LOC100929937
gene id: 9305:LOC100929937
uniprot id: G3VCN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CLDN14
gene id: 9305:CLDN14
uniprot id: G3VXY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9305:OTX1
gene id: 9305:OTX1
uniprot id: G3WD18
names: Subcellular Location Annotation
messages: Nucleus

9305:VGLL2
gene id: 9305:VGLL2
uniprot id: G3WDJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

9305:PHKG2
gene id: 9305:PHKG2
uniprot id: G3W787
names: Subunit
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

9305:OLFML1
gene id: 9305:OLFML1
uniprot id: A0A7N4NND2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:USP5
gene id: 9305:USP5
uniprot id: G3WTY6
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9305:LOC100927276
gene id: 9305:LOC100927276
uniprot id: G3WEK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M67A family. BRCC36 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Component of the BRCA1-A complex. Component of the BRISC complex. Both the BRCA1-A complex and the BRISC complex bind polyubiquitin.
messages: Cytoplasm
messages: Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.
messages: Nucleus
messages: spindle pole

9305:LOC100925813
gene id: 9305:LOC100925813
uniprot id: A0A7N4P5W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ACADSB
gene id: 9305:ACADSB
uniprot id: G3VCY3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9305:BGLAP
gene id: 9305:BGLAP
uniprot id: A0A7N4PPV9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Binds strongly to apatite and calcium.
messages: Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
messages: Secreted

9305:LOC100925756
gene id: 9305:LOC100925756
uniprot id: G3WG85
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

9305:GJB2
gene id: 9305:GJB2
uniprot id: A0A7N4P5V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9305:SFXN2
gene id: 9305:SFXN2
uniprot id: G3X372
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

9305:SLC34A1
gene id: 9305:SLC34A1
uniprot id: G3WPR4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

9305:IRF8
gene id: 9305:IRF8
uniprot id: A0A7N4V2J5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9305:SMAD7
gene id: 9305:SMAD7
uniprot id: G3WYR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9305:PRKD1
gene id: 9305:PRKD1
uniprot id: A0A7N4V735
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

9305:LOC100920148
gene id: 9305:LOC100920148
uniprot id: A0A7N4NH76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ASF1A
gene id: 9305:ASF1A
uniprot id: G3W4C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

9305:PDE6G
gene id: 9305:PDE6G
uniprot id: G3WIX9
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

9305:HCK
gene id: 9305:HCK
uniprot id: G3WE58
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9305:KCNH8
gene id: 9305:KCNH8
uniprot id: G3W1Y1
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

9305:C1H9orf64
gene id: 9305:C1H9orf64
uniprot id: G3WXZ8
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

9305:PDC
gene id: 9305:PDC
uniprot id: G3WSQ3
names: Similarity
messages: Belongs to the phosducin family.

9305:ANXA4
gene id: 9305:ANXA4
uniprot id: G3WNV2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

9305:MAGT1
gene id: 9305:MAGT1
uniprot id: G3WG52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:LOC100916837
gene id: 9305:LOC100916837
uniprot id: G3WRH8
names: Similarity
messages: Belongs to the intermediate filament family.

9305:CMAS
gene id: 9305:CMAS
uniprot id: G3WLL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
messages: Homotetramer; the active enzyme is formed by a dimer of dimers.

9305:LOC100918853
gene id: 9305:LOC100918853
uniprot id: A0A7N4V7G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100913673
gene id: 9305:LOC100913673
uniprot id: G3WER1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100920922
gene id: 9305:LOC100920922
uniprot id: A0A7N4P6Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ACTL6B
gene id: 9305:ACTL6B
uniprot id: A0A7N4NGL1
names: Similarity
messages: Belongs to the actin family.

9305:LOC100927341
gene id: 9305:LOC100927341
uniprot id: G3VQ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

9305:VIPAS39
gene id: 9305:VIPAS39
uniprot id: A0A7N4NLU4
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Vesicle

9305:ZDHHC12
gene id: 9305:ZDHHC12
uniprot id: A0A7N4NYR1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9305:RRM2B
gene id: 9305:RRM2B
uniprot id: G3WZC9
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

9305:PSKH2
gene id: 9305:PSKH2
uniprot id: G3W841
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:HTRA3
gene id: 9305:HTRA3
uniprot id: G3WT65
names: Similarity
messages: Belongs to the peptidase S1C family.

9305:FAM110D
gene id: 9305:FAM110D
uniprot id: G3W5C1
names: Similarity
messages: Belongs to the FAM110 family.

9305:EMG1
gene id: 9305:EMG1
uniprot id: G3WV86
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

9305:LOC100914525
gene id: 9305:LOC100914525
uniprot id: G3VKV6
names: Similarity
names: Subunit
messages: Belongs to the SFTPD family.
messages: Oligomeric complex of 4 set of homotrimers.

9305:LOC100931905
gene id: 9305:LOC100931905
uniprot id: A0A7N4P3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100923336
gene id: 9305:LOC100923336
uniprot id: G3VJJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ITIH5
gene id: 9305:ITIH5
uniprot id: G3X008
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9305:LOC100916042
gene id: 9305:LOC100916042
uniprot id: G3W9Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CYRIB
gene id: 9305:CYRIB
uniprot id: G3WJB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

9305:LOC100922250
gene id: 9305:LOC100922250
uniprot id: G3W4N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:WFIKKN2
gene id: 9305:WFIKKN2
uniprot id: A0A7N4PNF2
names: Similarity
messages: Belongs to the WFIKKN family.

9305:ATP1A2
gene id: 9305:ATP1A2
uniprot id: G3W5F0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:LGALS3
gene id: 9305:LGALS3
uniprot id: G3VNU5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

9305:LOC100932082
gene id: 9305:LOC100932082
uniprot id: G3VEX5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

9305:LOC100927223
gene id: 9305:LOC100927223
uniprot id: G3W1B0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

9305:LOC100916162
gene id: 9305:LOC100916162
uniprot id: A0A7N4NIY4
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

9305:ST6GALNAC2
gene id: 9305:ST6GALNAC2
uniprot id: A0A7N4PX47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9305:IFNG
gene id: 9305:IFNG
uniprot id: G3WQJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II (or gamma) interferon family.
messages: Homodimer.
messages: Secreted
messages: Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation. Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes. Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription. Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits. In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading. Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference. Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL. Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation.

9305:EME1
gene id: 9305:EME1
uniprot id: A0A7N4PI39
names: Similarity
messages: Belongs to the EME1/MMS4 family.

9305:VWA2
gene id: 9305:VWA2
uniprot id: A0A7N4NN05
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:ADCY4
gene id: 9305:ADCY4
uniprot id: G3VVT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9305:LOC100926346
gene id: 9305:LOC100926346
uniprot id: A0A7N4NYZ5
uniprot id: G3W9D9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

9305:PDLIM1
gene id: 9305:PDLIM1
uniprot id: G3WKQ6
names: Subcellular Location Annotation
messages: Z line

9305:DHRS9
gene id: 9305:DHRS9
uniprot id: G3WX97
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9305:BCO1
gene id: 9305:BCO1
uniprot id: G3W0D4
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

9305:LOC100920064
gene id: 9305:LOC100920064
uniprot id: A0A7N4NWN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TENM2
gene id: 9305:TENM2
uniprot id: A0A7N4NMU8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:LOC100914771
gene id: 9305:LOC100914771
uniprot id: G3WI18
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9305:LOC100932984
gene id: 9305:LOC100932984
uniprot id: A0A7N4P3X1
uniprot id: G3X1D9
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

9305:PSMB5
gene id: 9305:PSMB5
uniprot id: G3WKE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB5 displays a chymotrypsin-like activity.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9305:TCTA
gene id: 9305:TCTA
uniprot id: A0A7N4PJU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTA family.
messages: May be required for cellular fusion during osteoclastogenesis.
messages: Membrane

9305:TRMT10C
gene id: 9305:TRMT10C
uniprot id: G3W497
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

9305:ARMC8
gene id: 9305:ARMC8
uniprot id: G3VYC8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9305:SUGP1
gene id: 9305:SUGP1
uniprot id: G3WGC4
names: Subcellular Location Annotation
messages: Nucleus

9305:FGGY
gene id: 9305:FGGY
uniprot id: G3VRY7
names: Similarity
messages: Belongs to the FGGY kinase family.

9305:SLC25A47
gene id: 9305:SLC25A47
uniprot id: G3WM98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9305:LOC100913765
gene id: 9305:LOC100913765
uniprot id: A0A7N4NWH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:AHSA1
gene id: 9305:AHSA1
uniprot id: G3VQM5
names: Similarity
messages: Belongs to the AHA1 family.

9305:ZDHHC4
gene id: 9305:ZDHHC4
uniprot id: G3VIW1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9305:NDUFAF7
gene id: 9305:NDUFAF7
uniprot id: G3W920
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

9305:ATG16L2
gene id: 9305:ATG16L2
uniprot id: A0A7N4V4F2
uniprot id: G3VTT0
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

9305:ITGA6
gene id: 9305:ITGA6
uniprot id: A0A7N4NZU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9305:DRD3
gene id: 9305:DRD3
uniprot id: G3VZA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.
messages: Membrane

9305:TMEM17
gene id: 9305:TMEM17
uniprot id: G3WMS7
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100920969
gene id: 9305:LOC100920969
uniprot id: G3W3S2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

9305:EMP2
gene id: 9305:EMP2
uniprot id: A0A7N4UYN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Membrane raft
messages: Nucleus
messages: perinuclear region

9305:LMBR1L
gene id: 9305:LMBR1L
uniprot id: G3VSI5
names: Similarity
messages: Belongs to the LIMR family.

9305:NUDT1
gene id: 9305:NUDT1
uniprot id: A0A7N4PIH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

9305:MPPED2
gene id: 9305:MPPED2
uniprot id: G3WBR2
names: Similarity
messages: Belongs to the UPF0046 family.

9305:TRAPPC4
gene id: 9305:TRAPPC4
uniprot id: G3WA41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

9305:ARL11
gene id: 9305:ARL11
uniprot id: G3VQU9
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

9305:LOC100914326
gene id: 9305:LOC100914326
uniprot id: G3WD90
names: Similarity
messages: Belongs to the HPF1 family.

9305:IL18
gene id: 9305:IL18
uniprot id: A0A7N4NK70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Secreted

9305:SERPINI1
gene id: 9305:SERPINI1
uniprot id: G3VI34
names: Similarity
messages: Belongs to the serpin family.

9305:ZNRD1
gene id: 9305:ZNRD1
uniprot id: A0A7N4PQ74
uniprot id: G3VEY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
messages: nucleolus

9305:LOC100927922
gene id: 9305:LOC100927922
uniprot id: A0A7N4PY73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ND4L
gene id: 9305:ND4L
uniprot id: G1FKC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

9305:TMCC3
gene id: 9305:TMCC3
uniprot id: A0A7N4V2D6
names: Similarity
messages: Belongs to the TEX28 family.

9305:COPS9
gene id: 9305:COPS9
uniprot id: G3WYG9
names: Similarity
messages: Belongs to the CSN9 family.

9305:KCNG1
gene id: 9305:KCNG1
uniprot id: G3X319
names: Subcellular Location Annotation
messages: Membrane

9305:ACTA1
gene id: 9305:ACTA1
uniprot id: G3WM41
names: Similarity
messages: Belongs to the actin family.

9305:XRCC3
gene id: 9305:XRCC3
uniprot id: A0A7N4PJ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Cytoplasm
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.
messages: Nucleus

9305:TRAPPC2
gene id: 9305:TRAPPC2
uniprot id: A0A7N4P1E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

9305:POT1
gene id: 9305:POT1
uniprot id: G3WTD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

9305:RGS2
gene id: 9305:RGS2
uniprot id: A0A7N4V115
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: nucleolus

9305:LOC100926920
gene id: 9305:LOC100926920
uniprot id: G3VQN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100922640
gene id: 9305:LOC100922640
uniprot id: G3VK96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:HTR2B
gene id: 9305:HTR2B
uniprot id: G3VRJ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts (via C-terminus) with MPDZ.
messages: Membrane
messages: synaptosome

9305:GPLD1
gene id: 9305:GPLD1
uniprot id: G3VXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPLD1 family.
messages: Secreted

9305:LOC100931010
gene id: 9305:LOC100931010
uniprot id: A0A7N4PRP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:RPL32
gene id: 9305:RPL32
uniprot id: G3WHS6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

9305:ISY1
gene id: 9305:ISY1
uniprot id: A0A7N4PQP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

9305:BMX
gene id: 9305:BMX
uniprot id: G3VBH5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9305:ZBED1
gene id: 9305:ZBED1
uniprot id: A0A7N4NMI2
names: Subcellular Location Annotation
messages: Nucleus

9305:TOMM40L
gene id: 9305:TOMM40L
uniprot id: A0A7N4PXH0
uniprot id: G3WW36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

9305:ANP32E
gene id: 9305:ANP32E
uniprot id: A0A7N4V0R9
names: Similarity
messages: Belongs to the ANP32 family.

9305:LOC100922493
gene id: 9305:LOC100922493
uniprot id: G3W950
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PSMB10
gene id: 9305:PSMB10
uniprot id: G3W0G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9305:ERMAP
gene id: 9305:ERMAP
uniprot id: G3WQ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

9305:LEP
gene id: 9305:LEP
uniprot id: A0A7N4NJU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the leptin family.
messages: Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductive function, regulates pancreatic beta-cell function and insulin secretion, is pro-angiogenic for endothelial cell and affects innate and adaptive immunity. In the arcuate nucleus of the hypothalamus, activates by depolarization POMC neurons inducing FOS and SOCS3 expression to release anorexigenic peptides and inhibits by hyperpolarization NPY neurons inducing SOCS3 with a consequent reduction on release of orexigenic peptides. In addition to its known satiety inducing effect, has a modulatory role in nutrient absorption. In the intestine, reduces glucose absorption by enterocytes by activating PKC and leading to a sequential activation of p38, PI3K and ERK signaling pathways which exerts an inhibitory effect on glucose absorption. Acts as a growth factor on certain tissues, through the activation of different signaling pathways increases expression of genes involved in cell cycle regulation such as CCND1, via JAK2-STAT3 pathway, or VEGFA, via MAPK1/3 and PI3K-AKT1 pathways. May also play an apoptotic role via JAK2-STAT3 pathway and up-regulation of BIRC5 expression. Pro-angiogenic, has mitogenic activity on vascular endothelial cells and plays a role in matrix remodeling by regulating the expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). In innate immunity, modulates the activity and function of neutrophils by in…
messages: Secreted

9305:PSMC5
gene id: 9305:PSMC5
uniprot id: G3WIV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

9305:SLC25A46
gene id: 9305:SLC25A46
uniprot id: A0A7N4PVC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

9305:PCSK1
gene id: 9305:PCSK1
uniprot id: G3VJH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
messages: Vesicle
messages: secretory vesicle

9305:TRH
gene id: 9305:TRH
uniprot id: A0A7N4NMF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

9305:S100A10
gene id: 9305:S100A10
uniprot id: A0A7N4V4H6
names: Function
messages: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.

9305:TRNAU1AP
gene id: 9305:TRNAU1AP
uniprot id: A0A7N4P397
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis.
messages: Nucleus

9305:TRAPPC13
gene id: 9305:TRAPPC13
uniprot id: G3WFL4
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

9305:CCDC130
gene id: 9305:CCDC130
uniprot id: G3WDP9
names: Similarity
messages: Belongs to the CWC16 family.

9305:MCTP2
gene id: 9305:MCTP2
uniprot id: A0A7N4PVQ7
names: Subcellular Location Annotation
messages: Membrane

9305:MARS1
gene id: 9305:MARS1
uniprot id: A0A7N4PRU3
uniprot id: G3VYN2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9305:LOC100928641
gene id: 9305:LOC100928641
uniprot id: G3VRU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9305:LOC100922169
gene id: 9305:LOC100922169
uniprot id: G3WIJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

9305:LOC100914215
gene id: 9305:LOC100914215
uniprot id: A0A7N4NXH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9305:LOC100920562
gene id: 9305:LOC100920562
uniprot id: G3VQI3
uniprot id: G3WSM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

9305:AGMAT
gene id: 9305:AGMAT
uniprot id: G3W5P0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

9305:ATP6V1C1
gene id: 9305:ATP6V1C1
uniprot id: A0A7N4NH74
uniprot id: G3X317
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

9305:LOC100917175
gene id: 9305:LOC100917175
uniprot id: K9HXI3
names: Similarity
messages: Belongs to the MHC class I family.

9305:HOXA1
gene id: 9305:HOXA1
uniprot id: G3WWK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

9305:LTB
gene id: 9305:LTB
uniprot id: G3VNG6
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9305:SLC16A14
gene id: 9305:SLC16A14
uniprot id: G3X0F6
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100929712
gene id: 9305:LOC100929712
uniprot id: G3VG75
names: Function
names: Similarity
messages: Belongs to the CMP-Neu5Ac hydroxylase family.
messages: Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. Catalyzes the conversion of CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells.

9305:S1PR1
gene id: 9305:S1PR1
uniprot id: A0A7N4PTR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC105750284
gene id: 9305:LOC105750284
uniprot id: G3WIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:SOD2
gene id: 9305:SOD2
uniprot id: A0A7N4PQA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

9305:LOC100929289
gene id: 9305:LOC100929289
uniprot id: A0A7N4NLK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:FTHL17
gene id: 9305:FTHL17
uniprot id: G3X002
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9305:ITGA5
gene id: 9305:ITGA5
uniprot id: G3WC24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9305:NIPA2
gene id: 9305:NIPA2
uniprot id: G3VYH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9305:RAG2
gene id: 9305:RAG2
uniprot id: A0A7N4P622
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

9305:LOC100929552
gene id: 9305:LOC100929552
uniprot id: G3W3I5
uniprot id: G3W3Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9305:LOC100927475
gene id: 9305:LOC100927475
uniprot id: A0A7N4V3N9
uniprot id: G3W1A9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

9305:CEL
gene id: 9305:CEL
uniprot id: G3VZE3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

9305:FAM32A
gene id: 9305:FAM32A
uniprot id: A0A7N4PVA0
names: Similarity
messages: Belongs to the FAM32 family.

9305:LOC100925879
gene id: 9305:LOC100925879
uniprot id: G3VX64
names: Subcellular Location Annotation
messages: Membrane

9305:GJB3
gene id: 9305:GJB3
uniprot id: A0A7N4P4D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9305:MSTN
gene id: 9305:MSTN
uniprot id: G3WMK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked. Interacts with WFIKKN2, leading to inhibit its activity. Interacts with FSTL3.
messages: Secreted

9305:SNX11
gene id: 9305:SNX11
uniprot id: A0A7N4PDF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

9305:LOC100919047
gene id: 9305:LOC100919047
uniprot id: A0A7N4NZ53
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

9305:CEMIP2
gene id: 9305:CEMIP2
uniprot id: A0A7N4PV12
uniprot id: G3VTP2
names: Similarity
messages: Belongs to the CEMIP family.

9305:RND3
gene id: 9305:RND3
uniprot id: G3WXU2
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

9305:ORMDL1
gene id: 9305:ORMDL1
uniprot id: A0A7N4PU65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

9305:PER1
gene id: 9305:PER1
uniprot id: A0A7N4NIK5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9305:GPAT3
gene id: 9305:GPAT3
uniprot id: G3VZS8
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9305:UTP15
gene id: 9305:UTP15
uniprot id: G3WJV4
names: Subcellular Location Annotation
messages: nucleolus

9305:CCM2
gene id: 9305:CCM2
uniprot id: A0A7N4PAQ7
uniprot id: A0A7N4PGS0
uniprot id: G3VYU4
names: Similarity
messages: Belongs to the CCM2 family.

9305:PPIL3
gene id: 9305:PPIL3
uniprot id: A0A7N4V1S1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9305:LOC100916704
gene id: 9305:LOC100916704
uniprot id: G3VGF4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:AK3
gene id: 9305:AK3
uniprot id: A0A7N4NTC5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

9305:GADD45B
gene id: 9305:GADD45B
uniprot id: A0A7N4PYY6
names: Similarity
messages: Belongs to the GADD45 family.

9305:LOC100931665
gene id: 9305:LOC100931665
uniprot id: A0A7N4PDM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:IER2
gene id: 9305:IER2
uniprot id: A0A7N4PK74
names: Similarity
messages: Belongs to the IER family.

9305:SSTR4
gene id: 9305:SSTR4
uniprot id: G3WHG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TRIAP1
gene id: 9305:TRIAP1
uniprot id: A0A7N4NNR4
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

9305:PKP4
gene id: 9305:PKP4
uniprot id: G3X1Y9
names: Similarity
messages: Belongs to the beta-catenin family.

9305:NMB
gene id: 9305:NMB
uniprot id: G3WTK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted
messages: neuron projection

9305:HSPD1
gene id: 9305:HSPD1
uniprot id: G3WZS7
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

9305:MDH2
gene id: 9305:MDH2
uniprot id: G3WJR3
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

9305:ABHD2
gene id: 9305:ABHD2
uniprot id: G3WT24
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

9305:SLC35F1
gene id: 9305:SLC35F1
uniprot id: A0A7N4NL53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

9305:EMC4
gene id: 9305:EMC4
uniprot id: G3VT98
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC4 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:GGNBP2
gene id: 9305:GGNBP2
uniprot id: G3VRR9
names: Function
messages: May be involved in spermatogenesis.

9305:SRP9
gene id: 9305:SRP9
uniprot id: G3WK96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

9305:MYO1B
gene id: 9305:MYO1B
uniprot id: A0A7N4PHC9
uniprot id: G3WYS8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9305:NKD2
gene id: 9305:NKD2
uniprot id: A0A7N4NNP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9305:NME4
gene id: 9305:NME4
uniprot id: G3W378
names: Similarity
messages: Belongs to the NDK family.

9305:GPR180
gene id: 9305:GPR180
uniprot id: G3WWU9
names: Subcellular Location Annotation
messages: Membrane

9305:EPO
gene id: 9305:EPO
uniprot id: G3W289
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Secreted

9305:SMARCA4
gene id: 9305:SMARCA4
uniprot id: G3VF88
uniprot id: G3VF89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

9305:DLX1
gene id: 9305:DLX1
uniprot id: A0A7N4PXM6
uniprot id: G3WVJ1
names: Subcellular Location Annotation
messages: Nucleus

9305:PKIB
gene id: 9305:PKIB
uniprot id: G3VED5
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

9305:FABP4
gene id: 9305:FABP4
uniprot id: A0A7N4UXM2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9305:LOC100919718
gene id: 9305:LOC100919718
uniprot id: A0A7N4NP99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:NR2F1
gene id: 9305:NR2F1
uniprot id: A0A7N4PKD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9305:LOC100913242
gene id: 9305:LOC100913242
uniprot id: G3WPZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ACSS1
gene id: 9305:ACSS1
uniprot id: G3VNY8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9305:GDAP2
gene id: 9305:GDAP2
uniprot id: G3VMC6
names: Similarity
messages: Belongs to the GDAP2 family.

9305:TLE3
gene id: 9305:TLE3
uniprot id: A0A7N4PMD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

9305:FOXF2
gene id: 9305:FOXF2
uniprot id: G3WHK3
names: Subcellular Location Annotation
messages: Nucleus

9305:SMIM5
gene id: 9305:SMIM5
uniprot id: A0A7N4Q141
names: Subcellular Location Annotation
messages: Membrane

9305:TNMD
gene id: 9305:TNMD
uniprot id: G3VID0
names: Similarity
messages: Belongs to the chondromodulin-1 family.

9305:UST
gene id: 9305:UST
uniprot id: A0A7N4PPT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

9305:GLYR1
gene id: 9305:GLYR1
uniprot id: A0A7N4P859
uniprot id: A0A7N4P9U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Chromosome

9305:PAXBP1
gene id: 9305:PAXBP1
uniprot id: G3W1S5
names: Similarity
messages: Belongs to the GCF family.

9305:REM1
gene id: 9305:REM1
uniprot id: G3WNH2
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

9305:ADCK5
gene id: 9305:ADCK5
uniprot id: A0A7N4NV28
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

9305:EPYC
gene id: 9305:EPYC
uniprot id: G3VIK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: extracellular matrix

9305:PTS
gene id: 9305:PTS
uniprot id: A0A7N4PTE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

9305:CD40LG
gene id: 9305:CD40LG
uniprot id: A0A7N4NJG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

9305:LOC100916571
gene id: 9305:LOC100916571
uniprot id: G3VEY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100925039
gene id: 9305:LOC100925039
uniprot id: A0A7N4NL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:COX3
gene id: 9305:COX3
uniprot id: G1FKC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

9305:CMC1
gene id: 9305:CMC1
uniprot id: A0A7N4PF96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

9305:LOC100926318
gene id: 9305:LOC100926318
uniprot id: A0A7N4P8I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.

9305:RNMT
gene id: 9305:RNMT
uniprot id: A0A7N4PMF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus

9305:BARHL1
gene id: 9305:BARHL1
uniprot id: A0A7N4NI72
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100925107
gene id: 9305:LOC100925107
uniprot id: G3WBT7
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

9305:MCL1
gene id: 9305:MCL1
uniprot id: G3WBC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane
messages: nucleoplasm

9305:RPL4
gene id: 9305:RPL4
uniprot id: G3VHT1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

9305:HDHD2
gene id: 9305:HDHD2
uniprot id: A0A7N4NPZ2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

9305:KCNA10
gene id: 9305:KCNA10
uniprot id: G3VP89
names: Subcellular Location Annotation
messages: Membrane

9305:NIPA1
gene id: 9305:NIPA1
uniprot id: G3W059
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9305:KRT35
gene id: 9305:KRT35
uniprot id: G3VR19
names: Similarity
messages: Belongs to the intermediate filament family.

9305:SERPINE1
gene id: 9305:SERPINE1
uniprot id: G3VRY9
names: Similarity
messages: Belongs to the serpin family.

9305:LOC100931606
gene id: 9305:LOC100931606
uniprot id: G3VXJ6
uniprot id: G3W3K3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.

9305:PPP2CA
gene id: 9305:PPP2CA
uniprot id: G3WVY5
names: Similarity
messages: Belongs to the PPP phosphatase family.

9305:NSUN3
gene id: 9305:NSUN3
uniprot id: G3VJ01
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

9305:LOC100929577
gene id: 9305:LOC100929577
uniprot id: A0A7N4PVI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100924469
gene id: 9305:LOC100924469
uniprot id: G3VN27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100926076
gene id: 9305:LOC100926076
uniprot id: G3W241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:HSPA9
gene id: 9305:HSPA9
uniprot id: G3WI07
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9305:NELFE
gene id: 9305:NELFE
uniprot id: A0A7N4PGT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus

9305:BRIX1
gene id: 9305:BRIX1
uniprot id: G3WB09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

9305:LOC100916231
gene id: 9305:LOC100916231
uniprot id: G3WFN0
names: Subcellular Location Annotation
messages: Membrane

9305:SIX2
gene id: 9305:SIX2
uniprot id: A0A7N4P1Z7
names: Subcellular Location Annotation
messages: Nucleus

9305:STX16
gene id: 9305:STX16
uniprot id: A0A7N4V2Z2
uniprot id: G3WRF7
names: Similarity
messages: Belongs to the syntaxin family.

9305:LOC100923773
gene id: 9305:LOC100923773
uniprot id: G3W424
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Homodimer.
messages: Secreted

9305:TENT5A
gene id: 9305:TENT5A
uniprot id: A0A7N4PWT2
names: Similarity
messages: Belongs to the TENT family.

9305:HOXD1
gene id: 9305:HOXD1
uniprot id: G3WUG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

9305:LOC100935218
gene id: 9305:LOC100935218
uniprot id: G3VUV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CACNG1
gene id: 9305:CACNG1
uniprot id: G3WGD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

9305:FLOT1
gene id: 9305:FLOT1
uniprot id: A0A7N4PFS8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Cell membrane
messages: Endosome
messages: Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2. Interacts with ECPAS.
messages: Membrane
messages: caveola

9305:LYRM1
gene id: 9305:LYRM1
uniprot id: A0A7N4PTL4
names: Similarity
messages: Belongs to the complex I LYR family.

9305:LOC100923259
gene id: 9305:LOC100923259
uniprot id: G3VLP6
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

9305:ACMSD
gene id: 9305:ACMSD
uniprot id: A0A7N4V2L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

9305:CENPBD1
gene id: 9305:CENPBD1
uniprot id: G3W5F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

9305:PRKAB1
gene id: 9305:PRKAB1
uniprot id: G3X120
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

9305:MKS1
gene id: 9305:MKS1
uniprot id: G3WG81
names: Subcellular Location Annotation
messages: cilium basal body

9305:NCEH1
gene id: 9305:NCEH1
uniprot id: A0A7N4V5B8
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

9305:RIOK2
gene id: 9305:RIOK2
uniprot id: G3VXT7
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

9305:UBE2L6
gene id: 9305:UBE2L6
uniprot id: A0A7N4V240
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9305:DTD1
gene id: 9305:DTD1
uniprot id: A0A7N4PYN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

9305:CASS4
gene id: 9305:CASS4
uniprot id: A0A7N4P2J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

9305:LOC100934169
gene id: 9305:LOC100934169
uniprot id: G3WNE3
names: Similarity
messages: Belongs to the peptidase M10A family.

9305:LOC100934257
gene id: 9305:LOC100934257
uniprot id: G3WCC2
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

9305:LOC100934288
gene id: 9305:LOC100934288
uniprot id: A0A7N4PYE1
uniprot id: G3WQ15
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:GPAT4
gene id: 9305:GPAT4
uniprot id: G3WV51
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9305:ACTL7B
gene id: 9305:ACTL7B
uniprot id: G3W6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

9305:FREM2
gene id: 9305:FREM2
uniprot id: G3VII7
names: Similarity
messages: Belongs to the FRAS1 family.

9305:LOC100926245
gene id: 9305:LOC100926245
uniprot id: A0A7N4NY96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CITED2
gene id: 9305:CITED2
uniprot id: A0A7N4PST8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

9305:BHMT
gene id: 9305:BHMT
uniprot id: G3WPY2
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

9305:ADAMTS1
gene id: 9305:ADAMTS1
uniprot id: G3WKJ9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9305:YAF2
gene id: 9305:YAF2
uniprot id: G3VYJ3
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100930545
gene id: 9305:LOC100930545
uniprot id: G3VNY2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C14A family.
messages: Cytoplasm
messages: Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (Caspase-6 subunit p18) and a 11 kDa (Caspase-6 subunit p11) subunit.
messages: Nucleus

9305:AGPAT4
gene id: 9305:AGPAT4
uniprot id: G3VUK2
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9305:LTB4R
gene id: 9305:LTB4R
uniprot id: A0A7N4PJM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TIGD2
gene id: 9305:TIGD2
uniprot id: A0A7N4PNE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

9305:BNIP1
gene id: 9305:BNIP1
uniprot id: G3W0F4
names: Subcellular Location Annotation
messages: Membrane

9305:PSEN1
gene id: 9305:PSEN1
uniprot id: A0A7N4UZC4
uniprot id: G3WGI8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

9305:FGF14
gene id: 9305:FGF14
uniprot id: A0A7N4PWJ5
uniprot id: A0A7N4UWZ4
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9305:ALB
gene id: 9305:ALB
uniprot id: G3WQH5
names: Subcellular Location Annotation
messages: Secreted

9305:MAN2B2
gene id: 9305:MAN2B2
uniprot id: A0A7N4PJY6
uniprot id: G3VAF5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

9305:ZDHHC7
gene id: 9305:ZDHHC7
uniprot id: G3W8N5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9305:TAGLN3
gene id: 9305:TAGLN3
uniprot id: G3WU95
names: Similarity
messages: Belongs to the calponin family.

9305:CERS3
gene id: 9305:CERS3
uniprot id: G3VHI1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

9305:SLC50A1
gene id: 9305:SLC50A1
uniprot id: A0A7N4PX37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates sugar transport across membranes.
messages: Membrane

9305:ASCC3
gene id: 9305:ASCC3
uniprot id: G3WVG9
names: Similarity
messages: Belongs to the helicase family.

9305:DNTT
gene id: 9305:DNTT
uniprot id: G3VQ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus
messages: Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.

9305:KREMEN2
gene id: 9305:KREMEN2
uniprot id: G3VDU6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:RGS8
gene id: 9305:RGS8
uniprot id: G3VU30
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: Perikaryon
messages: dendrite

9305:ELP5
gene id: 9305:ELP5
uniprot id: A0A7N4PXE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

9305:TSEN54
gene id: 9305:TSEN54
uniprot id: G3X134
names: Similarity
messages: Belongs to the SEN54 family.

9305:LOC100916236
gene id: 9305:LOC100916236
uniprot id: G3VM25
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

9305:LOC100916460
gene id: 9305:LOC100916460
uniprot id: G3W9C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

9305:LAPTM4A
gene id: 9305:LAPTM4A
uniprot id: G3VWK7
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

9305:LOC100927083
gene id: 9305:LOC100927083
uniprot id: A0A7N4NQ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

9305:PHOX2A
gene id: 9305:PHOX2A
uniprot id: G3VX50
names: Subcellular Location Annotation
messages: Nucleus

9305:SENP6
gene id: 9305:SENP6
uniprot id: A0A7N4PZ26
uniprot id: G3WDB4
uniprot id: G3WDB5
names: Similarity
messages: Belongs to the peptidase C48 family.

9305:TRAF6
gene id: 9305:TRAF6
uniprot id: A0A7N4PPL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

9305:GPR34
gene id: 9305:GPR34
uniprot id: G3VFJ7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:LOC100923548
gene id: 9305:LOC100923548
uniprot id: A0A7N4PJK4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

9305:MBOAT1
gene id: 9305:MBOAT1
uniprot id: A0A7N4NVX3
uniprot id: G3WVF9
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100922568
gene id: 9305:LOC100922568
uniprot id: G3W692
names: Similarity
messages: Belongs to the intermediate filament family.

9305:TREH
gene id: 9305:TREH
uniprot id: G3WE94
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

9305:ORMDL3
gene id: 9305:ORMDL3
uniprot id: A0A7N4PS52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Interacts with SPTLC1.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.

9305:LOC100924731
gene id: 9305:LOC100924731
uniprot id: G3VUX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9305:LOC100916307
gene id: 9305:LOC100916307
uniprot id: A0A7N4PIL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:QSOX1
gene id: 9305:QSOX1
uniprot id: G3W7M3
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

9305:NCK2
gene id: 9305:NCK2
uniprot id: A0A7N4Q1G0
uniprot id: G3VZY8
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Membrane
messages: Secreted

9305:SLC41A1
gene id: 9305:SLC41A1
uniprot id: G3WUF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

9305:POLR2E
gene id: 9305:POLR2E
uniprot id: G3WAN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

9305:MGAT5
gene id: 9305:MGAT5
uniprot id: G3WJ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

9305:S100A16
gene id: 9305:S100A16
uniprot id: A0A7N4NYJ5
names: Similarity
messages: Belongs to the S-100 family.

9305:GJA1
gene id: 9305:GJA1
uniprot id: A0A7N4NN51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9305:NTRK3
gene id: 9305:NTRK3
uniprot id: A0A7N4NPH6
uniprot id: A0A7N4PXZ1
uniprot id: G3WY32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

9305:VEZT
gene id: 9305:VEZT
uniprot id: G3W1H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vezatin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction

9305:SLC44A4
gene id: 9305:SLC44A4
uniprot id: G3W1J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

9305:HNRNPA1
gene id: 9305:HNRNPA1
uniprot id: A0A7N4NYE2
uniprot id: A0A7N4PMM7
uniprot id: G3W829
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9305:SURF6
gene id: 9305:SURF6
uniprot id: A0A7N4P933
names: Similarity
messages: Belongs to the SURF6 family.

9305:WDR12
gene id: 9305:WDR12
uniprot id: G3VXW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

9305:KRT79
gene id: 9305:KRT79
uniprot id: G3VRH8
names: Similarity
messages: Belongs to the intermediate filament family.

9305:SPDL1
gene id: 9305:SPDL1
uniprot id: G3X0R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Spindly family.
messages: Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.
messages: Nucleus
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
messages: centrosome
messages: kinetochore
messages: spindle pole

9305:INA
gene id: 9305:INA
uniprot id: G3X1X5
names: Similarity
messages: Belongs to the intermediate filament family.

9305:EIF5
gene id: 9305:EIF5
uniprot id: G3WXG2
names: Function
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).

9305:DDX11
gene id: 9305:DDX11
uniprot id: G3WNZ4
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

9305:PPP3R1
gene id: 9305:PPP3R1
uniprot id: A0A7N4Q027
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

9305:LOC105749534
gene id: 9305:LOC105749534
uniprot id: A0A7N4PGI9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

9305:MCOLN2
gene id: 9305:MCOLN2
uniprot id: G3WTL6
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

9305:PDCL
gene id: 9305:PDCL
uniprot id: A0A7N4V0Y6
names: Similarity
messages: Belongs to the phosducin family.

9305:ADAM17
gene id: 9305:ADAM17
uniprot id: G3VVV2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:POLR2G
gene id: 9305:POLR2G
uniprot id: G3VUQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: Nucleus

9305:CPNE3
gene id: 9305:CPNE3
uniprot id: G3VWY6
names: Similarity
messages: Belongs to the copine family.

9305:LOC100914775
gene id: 9305:LOC100914775
uniprot id: A0A7N4V0F2
names: Similarity
messages: Belongs to the ficolin lectin family.

9305:LOC100920628
gene id: 9305:LOC100920628
uniprot id: G3VFM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TXNRD3
gene id: 9305:TXNRD3
uniprot id: G3WF07
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

9305:EIF3H
gene id: 9305:EIF3H
uniprot id: G3WQD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with RNF139; the interaction leads to protein translation inhibitions in a ubiquitination-dependent manner.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

9305:LOC100917721
gene id: 9305:LOC100917721
uniprot id: G3VDM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:KLHL36
gene id: 9305:KLHL36
uniprot id: A0A7N4V2N1
uniprot id: G3VRE7
names: Function
messages: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

9305:ADAMTS3
gene id: 9305:ADAMTS3
uniprot id: G3WCC6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9305:XPO1
gene id: 9305:XPO1
uniprot id: A0A7N4P1V0
uniprot id: G3WCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

9305:HAO1
gene id: 9305:HAO1
uniprot id: G3VF29
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

9305:LOC100924766
gene id: 9305:LOC100924766
uniprot id: A0A7N4NQ74
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:ERGIC2
gene id: 9305:ERGIC2
uniprot id: G3VQR3
uniprot id: G3VQR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

9305:SLC25A53
gene id: 9305:SLC25A53
uniprot id: A0A7N4NIT8
uniprot id: G3WGT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9305:ATPAF2
gene id: 9305:ATPAF2
uniprot id: A0A7N4PGH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

9305:MYOC
gene id: 9305:MYOC
uniprot id: G3WXB5
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion intermembrane space
messages: Mitochondrion outer membrane
messages: Rough endoplasmic reticulum
messages: cilium
messages: extracellular exosome
messages: extracellular matrix

9305:LOC100927892
gene id: 9305:LOC100927892
uniprot id: G3VY59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:HS3ST5
gene id: 9305:HS3ST5
uniprot id: G3WJQ9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9305:MRI1
gene id: 9305:MRI1
uniprot id: A0A7N4UZ31
uniprot id: G3WDI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

9305:TPRG1
gene id: 9305:TPRG1
uniprot id: G3WCP6
names: Similarity
messages: Belongs to the TPRG1 family.

9305:RCAN1
gene id: 9305:RCAN1
uniprot id: G3WV36
uniprot id: G3WV37
names: Similarity
messages: Belongs to the RCAN family.

9305:PSMB1
gene id: 9305:PSMB1
uniprot id: G3WSZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9305:KIF18A
gene id: 9305:KIF18A
uniprot id: G3WSK3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9305:MMP2
gene id: 9305:MMP2
uniprot id: G3WFR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M10A family.
messages: Interacts (via the C-terminal hemopexin-like domains-containing region) with the integrin alpha-V/beta-3; the interaction promotes vascular invasion in angiogenic vessels and melamoma cells. Interacts (via the C-terminal PEX domain) with TIMP2 (via the C-terminal); the interaction inhibits the degradation activity. Interacts with GSK3B.
messages: extracellular matrix

9305:SLC41A3
gene id: 9305:SLC41A3
uniprot id: G3WAE9
uniprot id: G3WAF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

9305:SMAGP
gene id: 9305:SMAGP
uniprot id: A0A7N4PEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAGP family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

9305:DRAM2
gene id: 9305:DRAM2
uniprot id: G3WDA3
names: Subcellular Location Annotation
messages: Membrane

9305:PARPBP
gene id: 9305:PARPBP
uniprot id: G3VSR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PARI family.
messages: Cytoplasm
messages: Nucleus

9305:TMOD1
gene id: 9305:TMOD1
uniprot id: G3WRK9
names: Subcellular Location Annotation
messages: cytoskeleton

9305:LOC100915117
gene id: 9305:LOC100915117
uniprot id: A0A7N4PZ80
names: Subcellular Location Annotation
messages: Membrane

9305:SLC39A6
gene id: 9305:SLC39A6
uniprot id: G3WU64
names: Subcellular Location Annotation
messages: Membrane

9305:WNT7A
gene id: 9305:WNT7A
uniprot id: A0A7N4PN03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9305:LDHD
gene id: 9305:LDHD
uniprot id: G3WBP4
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

9305:UBA52
gene id: 9305:UBA52
uniprot id: A0A7N4PSM3
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

9305:KIF2B
gene id: 9305:KIF2B
uniprot id: G3VZ52
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9305:MARCHF4
gene id: 9305:MARCHF4
uniprot id: G3WM13
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100914986
gene id: 9305:LOC100914986
uniprot id: G5EA71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine gamma family.
messages: Secreted

9305:SEC24A
gene id: 9305:SEC24A
uniprot id: G3WPN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9305:TM4SF1
gene id: 9305:TM4SF1
uniprot id: G5EA68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9305:KCNMB4
gene id: 9305:KCNMB4
uniprot id: G3VX28
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

9305:OXTR
gene id: 9305:OXTR
uniprot id: G3WCZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

9305:LOC100916723
gene id: 9305:LOC100916723
uniprot id: A0A7N4PKM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100920855
gene id: 9305:LOC100920855
uniprot id: A0A7N4P713
names: Similarity
messages: Belongs to the SUI1 family.

9305:SFXN1
gene id: 9305:SFXN1
uniprot id: A0A7N4P2V9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

9305:LOC100927711
gene id: 9305:LOC100927711
uniprot id: G3WRN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

9305:LOC100922045
gene id: 9305:LOC100922045
uniprot id: G3WY72
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

9305:PPIL4
gene id: 9305:PPIL4
uniprot id: A0A7N4NPH8
uniprot id: G3WXQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9305:LOC100914552
gene id: 9305:LOC100914552
uniprot id: G3WTP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:NDRG1
gene id: 9305:NDRG1
uniprot id: A0A7N4PMM3
uniprot id: G3WRD7
names: Similarity
messages: Belongs to the NDRG family.

9305:PIGP
gene id: 9305:PIGP
uniprot id: G3WMY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

9305:LOC100924880
gene id: 9305:LOC100924880
uniprot id: G3VV21
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9305:PDIA6
gene id: 9305:PDIA6
uniprot id: A0A7N4P346
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

9305:GSC
gene id: 9305:GSC
uniprot id: A0A7N4P6F9
names: Subcellular Location Annotation
messages: Nucleus

9305:CIAPIN1
gene id: 9305:CIAPIN1
uniprot id: A0A7N4NSJ3
uniprot id: G3WRE3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

9305:GHSR
gene id: 9305:GHSR
uniprot id: A0A7N4PWQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).

9305:MFSD8
gene id: 9305:MFSD8
uniprot id: G3WLV9
names: Subcellular Location Annotation
messages: Membrane

9305:ORC4
gene id: 9305:ORC4
uniprot id: A0A7N4PF70
uniprot id: G3WAY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

9305:DPYS
gene id: 9305:DPYS
uniprot id: A0A7N4V2C4
uniprot id: G3WHL7
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

9305:LOC100921663
gene id: 9305:LOC100921663
uniprot id: A0A7N4P5F3
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

9305:C4H6orf120
gene id: 9305:C4H6orf120
uniprot id: A0A7N4NN80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes.
messages: Secreted

9305:TMEM70
gene id: 9305:TMEM70
uniprot id: G3W7W4
names: Similarity
messages: Belongs to the TMEM70 family.

9305:CALCB
gene id: 9305:CALCB
uniprot id: A0A7N4V5T5
names: Similarity
messages: Belongs to the calcitonin family.

9305:ZDHHC22
gene id: 9305:ZDHHC22
uniprot id: A0A7N4P3J3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9305:ABCG1
gene id: 9305:ABCG1
uniprot id: G3WMN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

9305:UBE3A
gene id: 9305:UBE3A
uniprot id: A0A7N4NV51
uniprot id: G3W856
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

9305:SLC16A13
gene id: 9305:SLC16A13
uniprot id: G3VC65
names: Subcellular Location Annotation
messages: Membrane

9305:SLCO1A2
gene id: 9305:SLCO1A2
uniprot id: G3WUF9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:CHRDL2
gene id: 9305:CHRDL2
uniprot id: G3W438
names: Subcellular Location Annotation
messages: Secreted

9305:HOMEZ
gene id: 9305:HOMEZ
uniprot id: A0A7N4V421
uniprot id: G3WPK3
names: Subcellular Location Annotation
messages: Nucleus

9305:ERG28
gene id: 9305:ERG28
uniprot id: A0A7N4P6S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:CMTM3
gene id: 9305:CMTM3
uniprot id: G3VDH0
names: Subcellular Location Annotation
messages: Membrane

9305:PCNP
gene id: 9305:PCNP
uniprot id: G3W3S0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

9305:OTP
gene id: 9305:OTP
uniprot id: G3X0Z0
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100932338
gene id: 9305:LOC100932338
uniprot id: G3VN36
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

9305:FAM83A
gene id: 9305:FAM83A
uniprot id: G3WI28
names: Similarity
messages: Belongs to the FAM83 family.

9305:LOC100922691
gene id: 9305:LOC100922691
uniprot id: G3WLR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

9305:SLC10A1
gene id: 9305:SLC10A1
uniprot id: G3VK42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

9305:PFKFB3
gene id: 9305:PFKFB3
uniprot id: G3WJ62
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

9305:GPNMB
gene id: 9305:GPNMB
uniprot id: G3W1A5
names: Similarity
messages: Belongs to the PMEL/NMB family.

9305:TK1
gene id: 9305:TK1
uniprot id: G3X1C7
names: Similarity
messages: Belongs to the thymidine kinase family.

9305:LPAR6
gene id: 9305:LPAR6
uniprot id: A0A7N4PLE7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:IL26
gene id: 9305:IL26
uniprot id: A0A7N4PH38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

9305:STING1
gene id: 9305:STING1
uniprot id: G3WCT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: autophagosome membrane
messages: perinuclear region

9305:CEP76
gene id: 9305:CEP76
uniprot id: A0A7N4NWP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

9305:TUBD1
gene id: 9305:TUBD1
uniprot id: A0A7N4NJI3
uniprot id: G3WUD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Nucleus
messages: centriole
messages: cilium

9305:TMEM176A
gene id: 9305:TMEM176A
uniprot id: A0A7N4P9P0
names: Similarity
messages: Belongs to the TMEM176 family.

9305:INHBC
gene id: 9305:INHBC
uniprot id: G3VW78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

9305:ACAT1
gene id: 9305:ACAT1
uniprot id: G3WEN4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

9305:LOC105751160
gene id: 9305:LOC105751160
uniprot id: A0A7N4Q0J5
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

9305:PRPSAP1
gene id: 9305:PRPSAP1
uniprot id: A0A7N4NZ64
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

9305:C8A
gene id: 9305:C8A
uniprot id: G3VVQ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:OSMR
gene id: 9305:OSMR
uniprot id: G3WEM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

9305:LOC100933474
gene id: 9305:LOC100933474
uniprot id: G3W072
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9305:ALAS2
gene id: 9305:ALAS2
uniprot id: A0A7N4NX02
uniprot id: G3W082
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

9305:BTF3L4
gene id: 9305:BTF3L4
uniprot id: A0A7N4P307
names: Similarity
messages: Belongs to the NAC-beta family.

9305:RAD50
gene id: 9305:RAD50
uniprot id: G3WB07
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

9305:SNX10
gene id: 9305:SNX10
uniprot id: A0A7N4PHR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

9305:LOC100933335
gene id: 9305:LOC100933335
uniprot id: A0A7N4V0Q6
names: Subcellular Location Annotation
messages: Membrane

9305:MRPL44
gene id: 9305:MRPL44
uniprot id: G3W7K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

9305:RGS1
gene id: 9305:RGS1
uniprot id: A0A7N4V4D2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytosol

9305:YARS2
gene id: 9305:YARS2
uniprot id: G3VPN2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9305:RAB39A
gene id: 9305:RAB39A
uniprot id: A0A7N4V3Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

9305:SGCA
gene id: 9305:SGCA
uniprot id: G3WJL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: cytoskeleton

9305:ALDH7A1
gene id: 9305:ALDH7A1
uniprot id: G3WJ35
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

9305:PARVB
gene id: 9305:PARVB
uniprot id: A0A7N4P885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

9305:ZDHHC5
gene id: 9305:ZDHHC5
uniprot id: G3WSY8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9305:RPSA
gene id: 9305:RPSA
uniprot id: G3VXP4
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

9305:LOC100916977
gene id: 9305:LOC100916977
uniprot id: A0A7N4Q095
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:TATDN1
gene id: 9305:TATDN1
uniprot id: G3VY17
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

9305:ADAM33
gene id: 9305:ADAM33
uniprot id: G3WUH9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:AGT
gene id: 9305:AGT
uniprot id: G3WZF9
uniprot id: G3WZG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

9305:MLF2
gene id: 9305:MLF2
uniprot id: A0A7N4P192
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

9305:ADPRHL1
gene id: 9305:ADPRHL1
uniprot id: G3WUG1
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

9305:CDNF
gene id: 9305:CDNF
uniprot id: G3X224
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

9305:PHAX
gene id: 9305:PHAX
uniprot id: G3WIK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

9305:SLC35F2
gene id: 9305:SLC35F2
uniprot id: G3WIB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

9305:INSRR
gene id: 9305:INSRR
uniprot id: G3WV44
names: Subcellular Location Annotation
messages: Membrane

9305:BATF
gene id: 9305:BATF
uniprot id: A0A7N4PD30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

9305:GSTK1
gene id: 9305:GSTK1
uniprot id: G3VMY8
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

9305:HMGN3
gene id: 9305:HMGN3
uniprot id: A0A7N4P0F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function.
messages: Nucleus

9305:SPNS1
gene id: 9305:SPNS1
uniprot id: G3WH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

9305:PCNX4
gene id: 9305:PCNX4
uniprot id: G3WKU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

9305:LOC100934191
gene id: 9305:LOC100934191
uniprot id: G3WM93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

9305:ATP6V1H
gene id: 9305:ATP6V1H
uniprot id: A0A7N4NY11
uniprot id: A0A7N4P880
uniprot id: G3WN96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9305:OSGEP
gene id: 9305:OSGEP
uniprot id: A0A7N4NLM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least TP53RK, TPRKB, OSGEP and LAGE3; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
messages: Cytoplasm
messages: Nucleus

9305:CHGB
gene id: 9305:CHGB
uniprot id: G3WBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

9305:LOC100921373
gene id: 9305:LOC100921373
uniprot id: A0A7N4V2B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ATP5PF
gene id: 9305:ATP5PF
uniprot id: G3WBY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

9305:F9
gene id: 9305:F9
uniprot id: G3W4I8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:LOC100931911
gene id: 9305:LOC100931911
uniprot id: A0A7N4PBW6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:HS2ST1
gene id: 9305:HS2ST1
uniprot id: G3VQJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

9305:LOC100914443
gene id: 9305:LOC100914443
uniprot id: G3WZF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9305:LOC100920676
gene id: 9305:LOC100920676
uniprot id: G3VEN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:NDUFAF3
gene id: 9305:NDUFAF3
uniprot id: G3WPQ5
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

9305:KCNJ8
gene id: 9305:KCNJ8
uniprot id: G3WQR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9305:SAG
gene id: 9305:SAG
uniprot id: G3VMY5
names: Similarity
messages: Belongs to the arrestin family.

9305:IFT57
gene id: 9305:IFT57
uniprot id: G3WIG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

9305:MAP3K7
gene id: 9305:MAP3K7
uniprot id: A0A7N4PVT3
uniprot id: G3WZI8
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by pro-inflammatory cytokines and in response to physical and chemical stresses, including osmotic stress, oxidative stress, arsenic and ultraviolet light irradiation. Activated by 'Lys-63'-linked polyubiquitination and by autophosphorylation.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm

9305:ELOVL6
gene id: 9305:ELOVL6
uniprot id: A0A7N4V3T7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

9305:IL18R1
gene id: 9305:IL18R1
uniprot id: G3W1C1
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9305:GAA
gene id: 9305:GAA
uniprot id: G3VVM7
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:ITK
gene id: 9305:ITK
uniprot id: G3WSK6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9305:LOC105749295
gene id: 9305:LOC105749295
uniprot id: G3X2D7
uniprot id: G3X2D8
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

9305:LDHA
gene id: 9305:LDHA
uniprot id: A0A7N4PK07
uniprot id: G3WT28
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

9305:MGAT2
gene id: 9305:MGAT2
uniprot id: G3VUH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

9305:LOC100932136
gene id: 9305:LOC100932136
uniprot id: G3VR42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:SLC29A1
gene id: 9305:SLC29A1
uniprot id: G3WYI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

9305:RNF7
gene id: 9305:RNF7
uniprot id: G3WYG8
names: Similarity
messages: Belongs to the RING-box family.

9305:RTN1
gene id: 9305:RTN1
uniprot id: A0A7N4PSN1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:UBE4A
gene id: 9305:UBE4A
uniprot id: A0A7N4NLX9
uniprot id: G3WJA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

9305:LOC100931269
gene id: 9305:LOC100931269
uniprot id: G3WXV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:LOC100922209
gene id: 9305:LOC100922209
uniprot id: G3WH64
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:COL4A1
gene id: 9305:COL4A1
uniprot id: G3WDT4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

9305:INTS2
gene id: 9305:INTS2
uniprot id: A0A7N4PUH7
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

9305:LOC100917088
gene id: 9305:LOC100917088
uniprot id: G3VQV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9305:FIGNL1
gene id: 9305:FIGNL1
uniprot id: G3WW32
names: Similarity
messages: Belongs to the AAA ATPase family.

9305:PATL1
gene id: 9305:PATL1
uniprot id: G3VP14
names: Similarity
messages: Belongs to the PAT1 family.

9305:LOC100918969
gene id: 9305:LOC100918969
uniprot id: G3VSD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MAP2K5
gene id: 9305:MAP2K5
uniprot id: A0A7N4PXM2
uniprot id: G3WNC5
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:BCAP31
gene id: 9305:BCAP31
uniprot id: G3W549
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.

9305:TMEM14A
gene id: 9305:TMEM14A
uniprot id: G3WQ40
names: Similarity
messages: Belongs to the TMEM14 family.

9305:LOC100925611
gene id: 9305:LOC100925611
uniprot id: G3WNF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

9305:NCF2
gene id: 9305:NCF2
uniprot id: G3WJY7
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

9305:ELAC1
gene id: 9305:ELAC1
uniprot id: A0A7N4Q146
names: Subunit
messages: Homodimer.

9305:POLR3GL
gene id: 9305:POLR3GL
uniprot id: A0A7N4PPB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

9305:TSPAN12
gene id: 9305:TSPAN12
uniprot id: G3WFJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9305:DDX3X
gene id: 9305:DDX3X
uniprot id: G3W048
names: Similarity
messages: Belongs to the DEAD box helicase family.

9305:DUOX1
gene id: 9305:DUOX1
uniprot id: G3WYX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

9305:CHST10
gene id: 9305:CHST10
uniprot id: A0A7N4PI68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:PPP1R3C
gene id: 9305:PPP1R3C
uniprot id: A0A7N4V195
uniprot id: G3X3K1
names: Domain
names: Function
names: Subunit
messages: Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
messages: Interacts with PPP1CC catalytic subunit of PP1 and associates with glycogen. Forms complexes with glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.
messages: The N-terminal region is required for binding to PP1, the central region is required for binding to glycogen and the C-terminal region is required for binding to glycogen phosphorylase glycogen synthase and phosphorylase kinase.

9305:LOC100919171
gene id: 9305:LOC100919171
uniprot id: A0A7N4P3L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9305:ETNPPL
gene id: 9305:ETNPPL
uniprot id: G3VHJ6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

9305:EIF3D
gene id: 9305:EIF3D
uniprot id: G3WCF6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Cytoplasm
messages: Phosphorylated upon DNA damage, probably by ATM or ATR.
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. In the eIF-3 complex, EIF3D specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

9305:LOC100923025
gene id: 9305:LOC100923025
uniprot id: A0A7N4PRW0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9305:VPS4B
gene id: 9305:VPS4B
uniprot id: A0A7N4V1T8
uniprot id: G3X047
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9305:RHBG
gene id: 9305:RHBG
uniprot id: A0A7N4PMQ1
uniprot id: G3WNR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9305:LOC100913730
gene id: 9305:LOC100913730
uniprot id: A0A7N4PQN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

9305:ATF7IP
gene id: 9305:ATF7IP
uniprot id: G3WYY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

9305:VTI1A
gene id: 9305:VTI1A
uniprot id: A0A7N4PWH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

9305:TLL1
gene id: 9305:TLL1
uniprot id: G3W493
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100930860
gene id: 9305:LOC100930860
uniprot id: A0A7N4PDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:NDUFS8
gene id: 9305:NDUFS8
uniprot id: A0A7N4V4G4
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

9305:PRKG2
gene id: 9305:PRKG2
uniprot id: A0A7N4PIK1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

9305:SCNN1B
gene id: 9305:SCNN1B
uniprot id: G3W1E4
names: Subcellular Location Annotation
messages: Membrane

9305:RBCK1
gene id: 9305:RBCK1
uniprot id: A0A7N4PMQ0
uniprot id: G3VSL8
names: Similarity
messages: Belongs to the RBR family.

9305:LOC100925613
gene id: 9305:LOC100925613
uniprot id: G3VWE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:SPDYA
gene id: 9305:SPDYA
uniprot id: A0A7N4PCR2
names: Similarity
messages: Belongs to the Speedy/Ringo family.

9305:LOC100919497
gene id: 9305:LOC100919497
uniprot id: G3WNK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100929658
gene id: 9305:LOC100929658
uniprot id: A0A7N4Q0I2
uniprot id: G3VSB4
names: Subcellular Location Annotation
messages: Membrane

9305:TMEM11
gene id: 9305:TMEM11
uniprot id: A0A7N4P3A4
uniprot id: G3VFL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in mitochondrial morphogenesis.

9305:UCMA
gene id: 9305:UCMA
uniprot id: G3WQB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

9305:RRAGD
gene id: 9305:RRAGD
uniprot id: G3WMR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

9305:VWC2
gene id: 9305:VWC2
uniprot id: G3VW59
names: Subcellular Location Annotation
messages: Synapse

9305:PLIN5
gene id: 9305:PLIN5
uniprot id: G3VL52
names: Similarity
messages: Belongs to the perilipin family.

9305:BLK
gene id: 9305:BLK
uniprot id: G3WE04
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9305:RNF31
gene id: 9305:RNF31
uniprot id: A0A7N4NFN3
uniprot id: G3VEA8
names: Similarity
messages: Belongs to the RBR family.

9305:CCL21
gene id: 9305:CCL21
uniprot id: G3WY31
names: Subcellular Location Annotation
messages: Secreted

9305:GSTA1
gene id: 9305:GSTA1
uniprot id: A0A7N4NMT7
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

9305:SMU1
gene id: 9305:SMU1
uniprot id: G3WGW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

9305:MGRN1
gene id: 9305:MGRN1
uniprot id: A0A7N4PEJ5
uniprot id: G3W2V5
uniprot id: G3W2V6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

9305:NMNAT3
gene id: 9305:NMNAT3
uniprot id: A0A7N4UXE5
uniprot id: G3WJR8
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

9305:DYNC1I2
gene id: 9305:DYNC1I2
uniprot id: G3WRD3
names: Similarity
messages: Belongs to the dynein intermediate chain family.

9305:TMC6
gene id: 9305:TMC6
uniprot id: G3X1M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

9305:LOC100926333
gene id: 9305:LOC100926333
uniprot id: G3W241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:FABP1
gene id: 9305:FABP1
uniprot id: G3WAA6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

9305:TAS2R1
gene id: 9305:TAS2R1
uniprot id: A0A7N4P0V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9305:CSK
gene id: 9305:CSK
uniprot id: A0A7N4V2M7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9305:LOC100920457
gene id: 9305:LOC100920457
uniprot id: G3VBD0
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

9305:KLHL15
gene id: 9305:KLHL15
uniprot id: A0A7N4P206
names: Subcellular Location Annotation
messages: Nucleus

9305:AGA
gene id: 9305:AGA
uniprot id: G3VWM7
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

9305:TXNIP
gene id: 9305:TXNIP
uniprot id: G3X2Y5
names: Similarity
messages: Belongs to the arrestin family.

9305:LOC100932522
gene id: 9305:LOC100932522
uniprot id: G3WJK7
uniprot id: G3WSM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

9305:TP53INP2
gene id: 9305:TP53INP2
uniprot id: G3WZV8
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

9305:TBR1
gene id: 9305:TBR1
uniprot id: G3WVW3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9305:ZEB2
gene id: 9305:ZEB2
uniprot id: A0A7N4PLY8
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

9305:USP14
gene id: 9305:USP14
uniprot id: G3WPF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS.

9305:MRPL41
gene id: 9305:MRPL41
uniprot id: G3WAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

9305:GLE1
gene id: 9305:GLE1
uniprot id: G3X3D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

9305:RNASE12
gene id: 9305:RNASE12
uniprot id: G3VEQ9
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

9305:LOC100921482
gene id: 9305:LOC100921482
uniprot id: A0A7N4PJL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:BDKRB2
gene id: 9305:BDKRB2
uniprot id: A0A7N4V174
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

9305:FAM3D
gene id: 9305:FAM3D
uniprot id: G3VKA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

9305:TES
gene id: 9305:TES
uniprot id: A0A7N4NYW6
uniprot id: G3WKX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

9305:MYF5
gene id: 9305:MYF5
uniprot id: G3WJV7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

9305:CNKSR3
gene id: 9305:CNKSR3
uniprot id: G3VY28
names: Similarity
messages: Belongs to the CNKSR family.

9305:ZWILCH
gene id: 9305:ZWILCH
uniprot id: A0A7N4NYL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

9305:C2H9orf78
gene id: 9305:C2H9orf78
uniprot id: G3WG65
names: Similarity
messages: Belongs to the TLS1 family.

9305:PIK3R1
gene id: 9305:PIK3R1
uniprot id: A0A7N4PPX5
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

9305:LRP10
gene id: 9305:LRP10
uniprot id: A0A7N4PFD2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:NADK2
gene id: 9305:NADK2
uniprot id: G3VIN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

9305:HSDL2
gene id: 9305:HSDL2
uniprot id: A0A7N4PSY3
names: Subcellular Location Annotation
messages: Peroxisome

9305:HOMER2
gene id: 9305:HOMER2
uniprot id: G3WZ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

9305:RBM22
gene id: 9305:RBM22
uniprot id: G3WZQ9
names: Similarity
messages: Belongs to the SLT11 family.

9305:PTER
gene id: 9305:PTER
uniprot id: A0A7N4V3J6
uniprot id: G3VZ17
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LHFPL6
gene id: 9305:LHFPL6
uniprot id: A0A7N4UYQ4
names: Subcellular Location Annotation
messages: Membrane

9305:ITGAX
gene id: 9305:ITGAX
uniprot id: G3VIX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9305:LOC100921723
gene id: 9305:LOC100921723
uniprot id: A0A7N4PD47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:FABP7
gene id: 9305:FABP7
uniprot id: G3VLN6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9305:CKMT1A
gene id: 9305:CKMT1A
uniprot id: G3WMF9
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

9305:RMI1
gene id: 9305:RMI1
uniprot id: G3WXI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RMI1 family.
messages: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
messages: Nucleus

9305:LOC100934670
gene id: 9305:LOC100934670
uniprot id: G3W2W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

9305:MRPS18A
gene id: 9305:MRPS18A
uniprot id: A0A7N4UXE2
uniprot id: G3WQL4
names: Subcellular Location Annotation
messages: Mitochondrion

9305:LOC100919277
gene id: 9305:LOC100919277
uniprot id: G3WSK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

9305:ATP8
gene id: 9305:ATP8
uniprot id: G1FKC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase protein 8 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion membrane

9305:MAF1
gene id: 9305:MAF1
uniprot id: A0A7N4PLY2
uniprot id: G3VVI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

9305:FAM174C
gene id: 9305:FAM174C
uniprot id: A0A7N4PEM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

9305:IFITM5
gene id: 9305:IFITM5
uniprot id: A0A7N4NYF9
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9305:SGSH
gene id: 9305:SGSH
uniprot id: G3VKR9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9305:NEDD9
gene id: 9305:NEDD9
uniprot id: A0A7N4PIJ2
uniprot id: G3W026
uniprot id: G3W027
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

9305:EEF1D
gene id: 9305:EEF1D
uniprot id: A0A7N4NWQ1
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

9305:DOK2
gene id: 9305:DOK2
uniprot id: A0A7N4PGC6
uniprot id: G3WZM1
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

9305:LOC100928736
gene id: 9305:LOC100928736
uniprot id: A0A7N4NXZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100919393
gene id: 9305:LOC100919393
uniprot id: G3WEX2
names: Similarity
messages: Belongs to the globin family.

9305:LOC100921468
gene id: 9305:LOC100921468
uniprot id: G3W064
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MRPS21
gene id: 9305:MRPS21
uniprot id: A0A7N4PKJ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

9305:FABP9
gene id: 9305:FABP9
uniprot id: A0A7N4NTI3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9305:LOC100933041
gene id: 9305:LOC100933041
uniprot id: G3VJP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Endoplasmic reticulum

9305:BANP
gene id: 9305:BANP
uniprot id: G3VHZ1
names: Similarity
messages: Belongs to the BANP/SMAR1 family.

9305:SPON1
gene id: 9305:SPON1
uniprot id: G3W1M1
names: Subcellular Location Annotation
messages: extracellular matrix

9305:DIPK2B
gene id: 9305:DIPK2B
uniprot id: G3WV56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

9305:EXTL3
gene id: 9305:EXTL3
uniprot id: A0A7N4PK72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

9305:CD53
gene id: 9305:CD53
uniprot id: A0A7N4PEA5
uniprot id: G3WA72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9305:CALHM4
gene id: 9305:CALHM4
uniprot id: G3VWK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9305:RPL7L1
gene id: 9305:RPL7L1
uniprot id: A0A7N4PF84
uniprot id: G3WCG7
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

9305:LOC100920933
gene id: 9305:LOC100920933
uniprot id: G3W7Z8
names: Subcellular Location Annotation
messages: Membrane

9305:BTK
gene id: 9305:BTK
uniprot id: G3WK98
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9305:OTULIN
gene id: 9305:OTULIN
uniprot id: G3WD99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

9305:RPAP1
gene id: 9305:RPAP1
uniprot id: G3WY13
names: Similarity
messages: Belongs to the RPAP1 family.

9305:TAGLN2
gene id: 9305:TAGLN2
uniprot id: A0A7N4PQG6
names: Similarity
messages: Belongs to the calponin family.

9305:TMEM175
gene id: 9305:TMEM175
uniprot id: A0A7N4P2S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

9305:LOC100928795
gene id: 9305:LOC100928795
uniprot id: G3VQR5
names: Subcellular Location Annotation
messages: Membrane

9305:PTP4A3
gene id: 9305:PTP4A3
uniprot id: A0A7N4NGG7
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9305:TOMM20
gene id: 9305:TOMM20
uniprot id: A0A7N4V737
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

9305:RNF20
gene id: 9305:RNF20
uniprot id: G3WDN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

9305:TREX2
gene id: 9305:TREX2
uniprot id: A0A7N4PT14
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

9305:CREBBP
gene id: 9305:CREBBP
uniprot id: G3WLJ1
names: Subcellular Location Annotation
messages: Cytoplasm

9305:MFAP3L
gene id: 9305:MFAP3L
uniprot id: A0A7N4NRK1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:TMEM200A
gene id: 9305:TMEM200A
uniprot id: A0A7N4UYN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

9305:PGLYRP1
gene id: 9305:PGLYRP1
uniprot id: G3WWY1
names: Function
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
messages: Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems.

9305:ZGPAT
gene id: 9305:ZGPAT
uniprot id: A0A7N4PHV0
uniprot id: G3X020
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CHD4/Mi-2; the interaction is direct.
messages: Nucleus

9305:HSPB2
gene id: 9305:HSPB2
uniprot id: G3WJW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Nucleus

9305:MYF6
gene id: 9305:MYF6
uniprot id: G3WJP0
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100922956
gene id: 9305:LOC100922956
uniprot id: A0A7N4NWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

9305:LOC100934627
gene id: 9305:LOC100934627
uniprot id: A0A7N4NYL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9305:LOC100931403
gene id: 9305:LOC100931403
uniprot id: G3VCJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

9305:LOC100930365
gene id: 9305:LOC100930365
uniprot id: G3VMM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

9305:JPH2
gene id: 9305:JPH2
uniprot id: G3VIV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

9305:UTP11
gene id: 9305:UTP11
uniprot id: A0A7N4NK47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

9305:LPAR2
gene id: 9305:LPAR2
uniprot id: G3WCQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:GPR21
gene id: 9305:GPR21
uniprot id: A0A7N4P8K2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:SNX30
gene id: 9305:SNX30
uniprot id: A0A7N4P684
uniprot id: G3W4J9
names: Similarity
messages: Belongs to the sorting nexin family.

9305:EPHB4
gene id: 9305:EPHB4
uniprot id: G3W0Z3
names: Subcellular Location Annotation
messages: Membrane

9305:EXOSC2
gene id: 9305:EXOSC2
uniprot id: G3WU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

9305:LOC100915930
gene id: 9305:LOC100915930
uniprot id: G3W8C9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9305:PEX13
gene id: 9305:PEX13
uniprot id: G3WLZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

9305:LOC100917623
gene id: 9305:LOC100917623
uniprot id: A0A7N4NYG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:IFT122
gene id: 9305:IFT122
uniprot id: A0A7N4UXB1
names: Subcellular Location Annotation
messages: cilium

9305:DOCK2
gene id: 9305:DOCK2
uniprot id: G3X0W7
names: Similarity
messages: Belongs to the DOCK family.

9305:FNTA
gene id: 9305:FNTA
uniprot id: A0A7N4PRQ8
uniprot id: G3X2Q8
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

9305:ITGA4
gene id: 9305:ITGA4
uniprot id: G3WM33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9305:SATB2
gene id: 9305:SATB2
uniprot id: A0A7N4NYS2
uniprot id: G3WBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

9305:TENT5D
gene id: 9305:TENT5D
uniprot id: A0A7N4PI35
names: Similarity
messages: Belongs to the TENT family.

9305:NPC2
gene id: 9305:NPC2
uniprot id: G3X357
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

9305:UBR1
gene id: 9305:UBR1
uniprot id: G3W8M9
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

9305:ELOVL5
gene id: 9305:ELOVL5
uniprot id: A0A7N4NY58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: dendrite

9305:LOC100918704
gene id: 9305:LOC100918704
uniprot id: A0A7N4PZM4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9305:PDSS1
gene id: 9305:PDSS1
uniprot id: G3WDJ1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

9305:DUSP1
gene id: 9305:DUSP1
uniprot id: G3VH35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

9305:GMPR2
gene id: 9305:GMPR2
uniprot id: G3VMX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

9305:LOC100927334
gene id: 9305:LOC100927334
uniprot id: G3WGK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ARCN1
gene id: 9305:ARCN1
uniprot id: A0A7N4PM98
uniprot id: G3WFM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

9305:LOC100921329
gene id: 9305:LOC100921329
uniprot id: G3VY43
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100926993
gene id: 9305:LOC100926993
uniprot id: G3W361
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100916019
gene id: 9305:LOC100916019
uniprot id: G3VYV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ACSL6
gene id: 9305:ACSL6
uniprot id: A0A7N4NVU1
uniprot id: A0A7N4P6G4
uniprot id: G3W0J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

9305:EDN1
gene id: 9305:EDN1
uniprot id: G3WQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

9305:HOXB9
gene id: 9305:HOXB9
uniprot id: G3WHG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

9305:RARRES2
gene id: 9305:RARRES2
uniprot id: A0A7N4NZV4
uniprot id: G3W6Y7
names: Subcellular Location Annotation
messages: Secreted

9305:AGXT2
gene id: 9305:AGXT2
uniprot id: G3W826
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

9305:SF3B1
gene id: 9305:SF3B1
uniprot id: G3WZ55
uniprot id: G3WZ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

9305:SGO1
gene id: 9305:SGO1
uniprot id: A0A7N4P134
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

9305:HMCES
gene id: 9305:HMCES
uniprot id: A0A7N4NTI8
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

9305:PRRX1
gene id: 9305:PRRX1
uniprot id: A0A7N4NT33
uniprot id: A0A7N4PDG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

9305:AASDHPPT
gene id: 9305:AASDHPPT
uniprot id: A0A7N4P0E7
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

9305:NELFCD
gene id: 9305:NELFCD
uniprot id: G3WJN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus

9305:CLDN18
gene id: 9305:CLDN18
uniprot id: G3VPH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9305:LOC100924432
gene id: 9305:LOC100924432
uniprot id: G3WBG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:VPS26C
gene id: 9305:VPS26C
uniprot id: A0A7N4Q1E7
uniprot id: G3WJN2
names: Similarity
messages: Belongs to the VPS26 family.

9305:RECQL5
gene id: 9305:RECQL5
uniprot id: G3X0D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

9305:PSMD9
gene id: 9305:PSMD9
uniprot id: A0A7N4PDH5
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

9305:MANEA
gene id: 9305:MANEA
uniprot id: G3W8H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:CLPS
gene id: 9305:CLPS
uniprot id: A0A7N4NVC9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

9305:ASRGL1
gene id: 9305:ASRGL1
uniprot id: A0A7N4PUA0
names: Similarity
names: Subunit
messages: Belongs to the Ntn-hydrolase family.
messages: Heterodimer of an alpha and beta chain produced by autocleavage. This heterodimer may then dimerize in turn, giving rise to a heterotetramer.

9305:RPL21
gene id: 9305:RPL21
uniprot id: G3VCP1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

9305:MRAP2
gene id: 9305:MRAP2
uniprot id: G3W7B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:LOC100920353
gene id: 9305:LOC100920353
uniprot id: A0A7N4PZX5
names: Subcellular Location Annotation
messages: Membrane

9305:BMP2
gene id: 9305:BMP2
uniprot id: A0A7N4NKL3
names: Similarity
messages: Belongs to the TGF-beta family.

9305:ATG4C
gene id: 9305:ATG4C
uniprot id: A0A7N4P8Y1
uniprot id: G3X197
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

9305:ABCG5
gene id: 9305:ABCG5
uniprot id: G3X3F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

9305:LOC100931063
gene id: 9305:LOC100931063
uniprot id: A0A7N4P2Y7
names: Subcellular Location Annotation
messages: Membrane

9305:GGACT
gene id: 9305:GGACT
uniprot id: A0A7N4PIE7
uniprot id: G3WM55
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine.

9305:CREB3L3
gene id: 9305:CREB3L3
uniprot id: G3W7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:CXCL12
gene id: 9305:CXCL12
uniprot id: A0A7N4P2D5
uniprot id: A0A7N4V065
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9305:FAM76B
gene id: 9305:FAM76B
uniprot id: A0A7N4P2L0
names: Similarity
messages: Belongs to the FAM76 family.

9305:CTH
gene id: 9305:CTH
uniprot id: G3WDG1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

9305:LOC105750430
gene id: 9305:LOC105750430
uniprot id: A0A7N4P9F8
names: Subcellular Location Annotation
messages: Membrane

9305:CCDC47
gene id: 9305:CCDC47
uniprot id: G3WHB6
names: Subcellular Location Annotation
messages: Membrane
messages: Rough endoplasmic reticulum membrane

9305:SMPD1
gene id: 9305:SMPD1
uniprot id: G3VUX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

9305:SIX6
gene id: 9305:SIX6
uniprot id: G3WRH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

9305:SKP1
gene id: 9305:SKP1
uniprot id: G3WVY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of multiple SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes formed of CUL1, SKP1, RBX1 and a variable F-box domain-containing protein as substrate-specific subunit.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.
messages: The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component.

9305:BECN1
gene id: 9305:BECN1
uniprot id: A0A7N4NUN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors.
messages: Belongs to the beclin family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Mitochondrion membrane
messages: Plays a central role in autophagy.
messages: autophagosome
messages: trans-Golgi network membrane

9305:GREM2
gene id: 9305:GREM2
uniprot id: G3WF61
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:KCNJ13
gene id: 9305:KCNJ13
uniprot id: A0A7N4PVQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9305:REEP5
gene id: 9305:REEP5
uniprot id: A0A7N4NWG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

9305:MTMR9
gene id: 9305:MTMR9
uniprot id: G3W443
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9305:IL15
gene id: 9305:IL15
uniprot id: A0A7N4V2G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

9305:SRFBP1
gene id: 9305:SRFBP1
uniprot id: A0A7N4PH01
names: Function
names: Subunit
messages: Interacts with SRF. Forms complexes with SRF and SRF cofactors ARID2, MYOCD and NKX2-5. Interacts with the N-terminus of SLC2A4.
messages: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.

9305:LOC100919888
gene id: 9305:LOC100919888
uniprot id: A0A7N4NUV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:C1H19orf53
gene id: 9305:C1H19orf53
uniprot id: A0A7N4P470
names: Function
names: Similarity
messages: Belongs to the UPF0390 family.
messages: May have a potential role in hypercalcemia of malignancy.

9305:ATP6V0E1
gene id: 9305:ATP6V0E1
uniprot id: A0A7N4NNM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9305:LOC100927424
gene id: 9305:LOC100927424
uniprot id: G3VU26
names: Subcellular Location Annotation
messages: Membrane

9305:VIPR1
gene id: 9305:VIPR1
uniprot id: G3W7S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

9305:BID
gene id: 9305:BID
uniprot id: G3W5W1
uniprot id: G3W5W2
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2.
messages: Induces caspases and apoptosis. Counters the protective effect of BCL2.
messages: Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
messages: Membrane
messages: Mitochondrion outer membrane

9305:PDRG1
gene id: 9305:PDRG1
uniprot id: A0A7N4PWG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

9305:POLR3G
gene id: 9305:POLR3G
uniprot id: G3VWU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Nucleus

9305:CCT8L2
gene id: 9305:CCT8L2
uniprot id: G3WJ07
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

9305:DCT
gene id: 9305:DCT
uniprot id: G3WXQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

9305:WNT8A
gene id: 9305:WNT8A
uniprot id: G3W8Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9305:MAP3K9
gene id: 9305:MAP3K9
uniprot id: A0A7N4PLE3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

9305:ARF6
gene id: 9305:ARF6
uniprot id: A0A7N4PES5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cell membrane
messages: Cleavage furrow
messages: Endosome membrane
messages: Midbody ring
messages: Recycling endosome membrane
messages: filopodium membrane
messages: ruffle

9305:PKLR
gene id: 9305:PKLR
uniprot id: A0A7N4P705
names: Similarity
messages: Belongs to the pyruvate kinase family.

9305:AQP9
gene id: 9305:AQP9
uniprot id: G3WD79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

9305:TBCA
gene id: 9305:TBCA
uniprot id: A0A7N4PYD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

9305:GJB6
gene id: 9305:GJB6
uniprot id: A0A7N4UYH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9305:GEM
gene id: 9305:GEM
uniprot id: G3WWE5
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

9305:TMED6
gene id: 9305:TMED6
uniprot id: G3WKT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:CEMIP
gene id: 9305:CEMIP
uniprot id: G3W7K8
names: Similarity
messages: Belongs to the CEMIP family.

9305:KCNMB3
gene id: 9305:KCNMB3
uniprot id: G3WVJ7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

9305:GCNT3
gene id: 9305:GCNT3
uniprot id: A0A7N4NS78
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

9305:FGF20
gene id: 9305:FGF20
uniprot id: A0A7N4PPK7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9305:PANX3
gene id: 9305:PANX3
uniprot id: G3WP76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

9305:SUPT4H1
gene id: 9305:SUPT4H1
uniprot id: A0A7N4PM86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

9305:LOC100917272
gene id: 9305:LOC100917272
uniprot id: G3VPG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100916105
gene id: 9305:LOC100916105
uniprot id: G3VL01
names: Subcellular Location Annotation
messages: Membrane

9305:MCM8
gene id: 9305:MCM8
uniprot id: G3WA38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

9305:RECQL
gene id: 9305:RECQL
uniprot id: G3WT75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

9305:LOC100918335
gene id: 9305:LOC100918335
uniprot id: G3VXP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:COQ5
gene id: 9305:COQ5
uniprot id: A0A7N4NQZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

9305:SLC45A2
gene id: 9305:SLC45A2
uniprot id: G3VL33
names: Subcellular Location Annotation
messages: Membrane

9305:LOC105749827
gene id: 9305:LOC105749827
uniprot id: G3VJ40
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

9305:LOC100913862
gene id: 9305:LOC100913862
uniprot id: G3VYV5
names: Similarity
messages: Belongs to the peptidase C14A family.

9305:HSD17B11
gene id: 9305:HSD17B11
uniprot id: A0A7N4PUX4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9305:RPS15A
gene id: 9305:RPS15A
uniprot id: G3WY83
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.

9305:HNRNPK
gene id: 9305:HNRNPK
uniprot id: A0A7N4PD36
uniprot id: G3WXL3
uniprot id: G3WXL4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm
messages: podosome

9305:TBX18
gene id: 9305:TBX18
uniprot id: G3WB37
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9305:FFAR3
gene id: 9305:FFAR3
uniprot id: G3VX91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9305:SLC17A9
gene id: 9305:SLC17A9
uniprot id: A0A7N4NXV9
names: Subcellular Location Annotation
messages: Membrane

9305:NDP
gene id: 9305:NDP
uniprot id: A0A7N4V2X2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:IFRD1
gene id: 9305:IFRD1
uniprot id: G3WNB2
uniprot id: G3WNB3
names: Similarity
messages: Belongs to the IFRD family.

9305:TM6SF1
gene id: 9305:TM6SF1
uniprot id: G3X0R8
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100914400
gene id: 9305:LOC100914400
uniprot id: G3WNG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9305:RPLP0
gene id: 9305:RPLP0
uniprot id: G3VF68
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

9305:LOC100922731
gene id: 9305:LOC100922731
uniprot id: G3VFG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CCNG1
gene id: 9305:CCNG1
uniprot id: G3VZL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin G subfamily.
messages: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
messages: Nucleus

9305:PAH
gene id: 9305:PAH
uniprot id: G3WCK3
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

9305:TMTC4
gene id: 9305:TMTC4
uniprot id: G3WJV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

9305:FRG1
gene id: 9305:FRG1
uniprot id: G3VUB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

9305:LOC100933576
gene id: 9305:LOC100933576
uniprot id: G3X0E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

9305:SCG2
gene id: 9305:SCG2
uniprot id: A0A7N4P442
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Interacts with Secretogranin III/SCG3.
messages: Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
messages: Secreted

9305:NGF
gene id: 9305:NGF
uniprot id: G3WIM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted

9305:TMCC1
gene id: 9305:TMCC1
uniprot id: G3WPI2
uniprot id: G3WPI3
names: Similarity
messages: Belongs to the TEX28 family.

9305:DCAF13
gene id: 9305:DCAF13
uniprot id: G3VWM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

9305:LOC100932434
gene id: 9305:LOC100932434
uniprot id: A0A7N4NGX2
uniprot id: G3WBF4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

9305:HDAC8
gene id: 9305:HDAC8
uniprot id: A0A7N4P686
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility. In addition to protein deacetylase activity, also has protein-lysine deacylase activity: acts as a protein decrotonylase by mediating decrotonylation ((2E)-butenoyl) of histones.
messages: Nucleus

9305:GPER1
gene id: 9305:GPER1
uniprot id: A0A7N4NT72
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:PSMB4
gene id: 9305:PSMB4
uniprot id: G3WPG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

9305:LOC100917515
gene id: 9305:LOC100917515
uniprot id: G3WA97
names: Similarity
messages: Belongs to the peptidase A1 family.

9305:LOC100918961
gene id: 9305:LOC100918961
uniprot id: G3WEY4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9305:LOC100932554
gene id: 9305:LOC100932554
uniprot id: G3WUM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100932401
gene id: 9305:LOC100932401
uniprot id: A0A7N4P7H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LIPG
gene id: 9305:LIPG
uniprot id: G3VR16
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:LOC100928430
gene id: 9305:LOC100928430
uniprot id: G3VYL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

9305:SLC6A2
gene id: 9305:SLC6A2
uniprot id: G3VJ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9305:AKAP8L
gene id: 9305:AKAP8L
uniprot id: A0A7N4PVD6
names: Similarity
messages: Belongs to the AKAP95 family.

9305:IRAK1BP1
gene id: 9305:IRAK1BP1
uniprot id: G3W368
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

9305:CD74
gene id: 9305:CD74
uniprot id: A0A7N4NGC7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:NIPAL4
gene id: 9305:NIPAL4
uniprot id: A0A7N4V2V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9305:MED1
gene id: 9305:MED1
uniprot id: G3WTX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

9305:MAPK7
gene id: 9305:MAPK7
uniprot id: G3WKJ6
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

9305:PITX2
gene id: 9305:PITX2
uniprot id: A0A7N4PEV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9305:MRPL24
gene id: 9305:MRPL24
uniprot id: G3WTU2
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

9305:KIFC2
gene id: 9305:KIFC2
uniprot id: G3W3E0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9305:NT5E
gene id: 9305:NT5E
uniprot id: G3WQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

9305:RPL31
gene id: 9305:RPL31
uniprot id: A0A7N4V0S3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

9305:CHI3L1
gene id: 9305:CHI3L1
uniprot id: A0A7N4NYD4
uniprot id: G3WVU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Monomer.
messages: extracellular space

9305:LOC100928142
gene id: 9305:LOC100928142
uniprot id: A0A7N4PVT9
uniprot id: A0A7N4Q024
uniprot id: G3W8G1
names: Similarity
messages: Belongs to the Luc7 family.

9305:SDC2
gene id: 9305:SDC2
uniprot id: G3W2N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

9305:TMEM63B
gene id: 9305:TMEM63B
uniprot id: A0A7N4P4T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

9305:LOC100923890
gene id: 9305:LOC100923890
uniprot id: G3VAX9
uniprot id: G3VHL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:IZUMO3
gene id: 9305:IZUMO3
uniprot id: G3VCF5
names: Similarity
messages: Belongs to the Izumo family.

9305:PRPF19
gene id: 9305:PRPF19
uniprot id: G3W6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

9305:NPY4R2
gene id: 9305:NPY4R2
uniprot id: A0A7N4UX36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9305:LOC100934436
gene id: 9305:LOC100934436
uniprot id: G3VHH1
names: Subcellular Location Annotation
messages: Membrane

9305:LOC105750795
gene id: 9305:LOC105750795
uniprot id: A0A7N4PG79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ORMDL2
gene id: 9305:ORMDL2
uniprot id: A0A7N4V856
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

9305:TUBG1
gene id: 9305:TUBG1
uniprot id: A0A7N4P414
uniprot id: G3WM03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
messages: centrosome

9305:CELF2
gene id: 9305:CELF2
uniprot id: A0A7N4NXF6
uniprot id: A0A7N4P2E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

9305:TBXAS1
gene id: 9305:TBXAS1
uniprot id: G3WIP2
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:STK17B
gene id: 9305:STK17B
uniprot id: G3WPU3
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:PRPSAP2
gene id: 9305:PRPSAP2
uniprot id: A0A7N4PHM2
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

9305:IGF2BP1
gene id: 9305:IGF2BP1
uniprot id: G3WMV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: P-body
messages: Stress granule
messages: filopodium
messages: lamellipodium

9305:LOC100931380
gene id: 9305:LOC100931380
uniprot id: G3W8I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Nucleus
messages: centriole
messages: cilium

9305:POLR3C
gene id: 9305:POLR3C
uniprot id: G3X2N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

9305:OXSM
gene id: 9305:OXSM
uniprot id: A0A7N4NHD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
messages: Mitochondrion

9305:LOC100927108
gene id: 9305:LOC100927108
uniprot id: G3VUQ6
uniprot id: G3VUQ7
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9305:VEPH1
gene id: 9305:VEPH1
uniprot id: G3X378
uniprot id: G3X379
names: Similarity
messages: Belongs to the MELT/VEPH family.

9305:GAPVD1
gene id: 9305:GAPVD1
uniprot id: G3W6Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAPVD1 family.
messages: Membrane

9305:PDHA1
gene id: 9305:PDHA1
uniprot id: A0A7N4PCJ7
uniprot id: G3WRQ6
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

9305:LPL
gene id: 9305:LPL
uniprot id: A0A7N4PZY2
uniprot id: G3W1U8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

9305:NOXRED1
gene id: 9305:NOXRED1
uniprot id: A0A7N4NWJ5
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

9305:LOC100929819
gene id: 9305:LOC100929819
uniprot id: G3W1I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:XPNPEP2
gene id: 9305:XPNPEP2
uniprot id: G3WPA6
names: Similarity
messages: Belongs to the peptidase M24B family.

9305:TFIP11
gene id: 9305:TFIP11
uniprot id: G3WMC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFP11/STIP family.
messages: Identified in the spliceosome C complex. Found in the Intron Large (IL) complex, a post-mRNA release spliceosomal complex containing the excised intron, U2, U5 and U6 snRNPs, and splicing factors. Interacts with TUFT1. Interacts with DHX15; indicative for a recruitment of DHX15 to the IL complex. Interacts with GCFC2.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
messages: Nucleus

9305:GBF1
gene id: 9305:GBF1
uniprot id: G3X3M7
names: Subcellular Location Annotation
messages: Golgi apparatus

9305:C4H17orf80
gene id: 9305:C4H17orf80
uniprot id: G3WSY0
uniprot id: G3WSY2
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

9305:SPATA20
gene id: 9305:SPATA20
uniprot id: G3VSI1
names: Function
names: Subcellular Location Annotation
messages: May play a role in fertility regulation.
messages: Secreted

9305:LOC100930838
gene id: 9305:LOC100930838
uniprot id: A0A7N4PU06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9305:LOC105750699
gene id: 9305:LOC105750699
uniprot id: A0A7N4P0C0
names: Function
names: Similarity
messages: Belongs to the calmodulin family.
messages: May be involved in calcium-mediated signal transduction.

9305:NIPSNAP3A
gene id: 9305:NIPSNAP3A
uniprot id: A0A7N4NZ52
names: Similarity
messages: Belongs to the NipSnap family.

9305:SLC39A2
gene id: 9305:SLC39A2
uniprot id: G3VUM9
names: Subcellular Location Annotation
messages: Membrane

9305:PYCARD
gene id: 9305:PYCARD
uniprot id: G3VLS4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inflammasome

9305:MRGPRF
gene id: 9305:MRGPRF
uniprot id: A0A7N4P1R0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:LOC100930272
gene id: 9305:LOC100930272
uniprot id: A0A7N4PY83
names: Similarity
messages: Belongs to the intermediate filament family.

9305:ZBTB8OS
gene id: 9305:ZBTB8OS
uniprot id: G3WB67
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

9305:PDZK1IP1
gene id: 9305:PDZK1IP1
uniprot id: A0A7N4V5D8
names: Subcellular Location Annotation
messages: Membrane

9305:GLIPR1L1
gene id: 9305:GLIPR1L1
uniprot id: G3VKV2
names: Similarity
messages: Belongs to the CRISP family.

9305:LOC100916098
gene id: 9305:LOC100916098
uniprot id: A0A7N4P5W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:EPHX1
gene id: 9305:EPHX1
uniprot id: G3WKR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9305:LOC100928884
gene id: 9305:LOC100928884
uniprot id: G3WHN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:NR4A2
gene id: 9305:NR4A2
uniprot id: G3WIG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Interacts with SFPQ, NCOR2, SIN3A and HADC1. The interaction with NCOR2 increases in the absence of PITX3. Interacts with PER2.
messages: Nucleus

9305:CPSF4
gene id: 9305:CPSF4
uniprot id: G3WDI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

9305:POLR2A
gene id: 9305:POLR2A
uniprot id: G3VJ85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

9305:LOC100923986
gene id: 9305:LOC100923986
uniprot id: G3WD23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MCEE
gene id: 9305:MCEE
uniprot id: A0A7N4P8J3
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

9305:ING3
gene id: 9305:ING3
uniprot id: A0A7N4NK03
uniprot id: G3WIR9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

9305:CDKN3
gene id: 9305:CDKN3
uniprot id: A0A7N4UXE0
uniprot id: G3W4P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
messages: perinuclear region

9305:GALNT5
gene id: 9305:GALNT5
uniprot id: G3WVT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9305:KDM4C
gene id: 9305:KDM4C
uniprot id: G3W3L5
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

9305:CPEB4
gene id: 9305:CPEB4
uniprot id: A0A7N4PCA3
uniprot id: A0A7N4PSB4
names: Similarity
messages: Belongs to the RRM CPEB family.

9305:GALM
gene id: 9305:GALM
uniprot id: G3WTZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldose epimerase family.
messages: Monomer.
messages: Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism.

9305:MKX
gene id: 9305:MKX
uniprot id: A0A7N4P0B5
names: Subcellular Location Annotation
messages: Nucleus

9305:RNF111
gene id: 9305:RNF111
uniprot id: A0A7N4PDR6
uniprot id: G3WQ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Arkadia family.
messages: PML body

9305:PSMG1
gene id: 9305:PSMG1
uniprot id: G3W230
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG1 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
messages: Forms a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer interacts directly with the PSMA5 and PSMA7 proteasome alpha subunits.

9305:PARP10
gene id: 9305:PARP10
uniprot id: G3VI98
names: Similarity
messages: Belongs to the ARTD/PARP family.

9305:PPP1R35
gene id: 9305:PPP1R35
uniprot id: G3WAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP1R35 family.
messages: centriole

9305:LOC100925599
gene id: 9305:LOC100925599
uniprot id: G3VXT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9305:AREG
gene id: 9305:AREG
uniprot id: G3VV74
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:IRX2
gene id: 9305:IRX2
uniprot id: G3VFC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

9305:PAQR5
gene id: 9305:PAQR5
uniprot id: G3WNR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9305:KLHL40
gene id: 9305:KLHL40
uniprot id: G3VZM8
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

9305:DAZL
gene id: 9305:DAZL
uniprot id: A0A7N4PYW3
names: Subcellular Location Annotation
messages: Cytoplasm

9305:LOC100913294
gene id: 9305:LOC100913294
uniprot id: A0A7N4V5M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9305:SLC25A12
gene id: 9305:SLC25A12
uniprot id: A0A7N4NRY5
uniprot id: G3WS12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

9305:NCAPG
gene id: 9305:NCAPG
uniprot id: G3WU03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

9305:BVES
gene id: 9305:BVES
uniprot id: G3WIZ0
names: Similarity
messages: Belongs to the popeye family.

9305:XPO7
gene id: 9305:XPO7
uniprot id: G3X025
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

9305:HOXD3
gene id: 9305:HOXD3
uniprot id: A0A7N4NKW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9305:ANKRD34A
gene id: 9305:ANKRD34A
uniprot id: G3X2W4
names: Similarity
messages: Belongs to the ANKRD34 family.

9305:RDH10
gene id: 9305:RDH10
uniprot id: G3WMQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

9305:FSHB
gene id: 9305:FSHB
uniprot id: G3W6F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9305:MBTPS1
gene id: 9305:MBTPS1
uniprot id: A0A7N4PHA5
names: Similarity
messages: Belongs to the peptidase S8 family.

9305:C6
gene id: 9305:C6
uniprot id: G3WFL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Component of the membrane attack complex (MAC). MAC assembly is initiated by proteolytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and 12-14 copies of the pore-forming subunit C9.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:LOC105749564
gene id: 9305:LOC105749564
uniprot id: G3W0S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9305:PSMC2
gene id: 9305:PSMC2
uniprot id: G3VN17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
messages: Cytoplasm

9305:DDR1
gene id: 9305:DDR1
uniprot id: G3W4S5
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100918237
gene id: 9305:LOC100918237
uniprot id: A0A7N4P4Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CFAP53
gene id: 9305:CFAP53
uniprot id: G3W8G4
names: Similarity
messages: Belongs to the CFAP53 family.

9305:LOC100916056
gene id: 9305:LOC100916056
uniprot id: G3VS82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

9305:CPNE2
gene id: 9305:CPNE2
uniprot id: G3WLA0
names: Similarity
messages: Belongs to the copine family.

9305:CAPN9
gene id: 9305:CAPN9
uniprot id: G3WZT3
names: Similarity
messages: Belongs to the peptidase C2 family.

9305:LOC100933193
gene id: 9305:LOC100933193
uniprot id: A0A7N4NNV4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9305:LOC100928536
gene id: 9305:LOC100928536
uniprot id: G3VGV3
uniprot id: G3VPF3
names: Subcellular Location Annotation
messages: Membrane

9305:MRPS18B
gene id: 9305:MRPS18B
uniprot id: A0A7N4NGX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily.
messages: Mitochondrion

9305:SLC11A1
gene id: 9305:SLC11A1
uniprot id: G3WUK2
names: Similarity
messages: Belongs to the NRAMP family.

9305:BBS2
gene id: 9305:BBS2
uniprot id: G3W852
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

9305:ARHGEF6
gene id: 9305:ARHGEF6
uniprot id: A0A7N4P4J6
uniprot id: A0A7N4PJ76
names: Subcellular Location Annotation
messages: lamellipodium

9305:NANOS3
gene id: 9305:NANOS3
uniprot id: G3WFF1
names: Similarity
messages: Belongs to the nanos family.

9305:GJD2
gene id: 9305:GJD2
uniprot id: A0A7N4NMC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9305:LOC100917204
gene id: 9305:LOC100917204
uniprot id: A0A7N4PFX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ND3
gene id: 9305:ND3
uniprot id: G1FKC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

9305:DDIT3
gene id: 9305:DDIT3
uniprot id: A0A7N4NPE2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Cytoplasm
messages: Heterodimer.
messages: Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. Negatively regulates; expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG). Inhibits the canonical Wnt signaling pathway by binding to TCF7L2/TCF4, impairing its DNA-binding properties and repressing its transcriptional activity. Plays a regulatory role in the inflammatory response through the induction of caspase-11 (CASP4/CASP11) which induces the activation of caspase-1 (CASP1) and both these caspases increase the activation of pro-IL1B to mature IL1B which is involved in the inflammatory response.
messages: Nucleus
messages: Phosphorylation at serine residues by MAPK14 enhances its transcriptional activation activity while phosphorylation at serine residues by CK2 inhibits its transcriptional activation activity.
messages: Ubiquitinated, leading to its degradation by the proteasome.

9305:PLCD4
gene id: 9305:PLCD4
uniprot id: G3WSY4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.
messages: Nucleus

9305:SLC35A4
gene id: 9305:SLC35A4
uniprot id: A0A7N4PHK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

9305:SCRN3
gene id: 9305:SCRN3
uniprot id: G3WT68
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

9305:MCM10
gene id: 9305:MCM10
uniprot id: G3WPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

9305:LOC100930293
gene id: 9305:LOC100930293
uniprot id: G3VHH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ORAI3
gene id: 9305:ORAI3
uniprot id: A0A7N4PD75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

9305:ARAF
gene id: 9305:ARAF
uniprot id: G3VVG4
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

9305:BTN1A1
gene id: 9305:BTN1A1
uniprot id: A0A7N4NIZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

9305:SYS1
gene id: 9305:SYS1
uniprot id: A0A7N4PTZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

9305:RPL35
gene id: 9305:RPL35
uniprot id: G3VQJ0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

9305:UIMC1
gene id: 9305:UIMC1
uniprot id: G3WAW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAP80 family.
messages: Nucleus

9305:RALA
gene id: 9305:RALA
uniprot id: A0A7N4P3Q9
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

9305:BEST2
gene id: 9305:BEST2
uniprot id: G3WSR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

9305:NAB2
gene id: 9305:NAB2
uniprot id: A0A7N4V810
uniprot id: G3VVL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

9305:SLC39A10
gene id: 9305:SLC39A10
uniprot id: A0A7N4NIJ4
uniprot id: G3WJ14
names: Subcellular Location Annotation
messages: Membrane

9305:ENTR1
gene id: 9305:ENTR1
uniprot id: G3VZU8
names: Similarity
messages: Belongs to the ENTR1 family.

9305:TEKT2
gene id: 9305:TEKT2
uniprot id: G3VSY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

9305:IMP3
gene id: 9305:IMP3
uniprot id: G3VVD1
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

9305:LOC105749029
gene id: 9305:LOC105749029
uniprot id: G3WGK3
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

9305:ARL14
gene id: 9305:ARL14
uniprot id: G3WWQ1
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

9305:NFKB1
gene id: 9305:NFKB1
uniprot id: G3VZA9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9305:CPN1
gene id: 9305:CPN1
uniprot id: G3WAE7
names: Similarity
messages: Belongs to the peptidase M14 family.

9305:LOC100933134
gene id: 9305:LOC100933134
uniprot id: A0A7N4NJB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100926976
gene id: 9305:LOC100926976
uniprot id: A0A7N4P1R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRAME family. LRRC14 subfamily.
messages: Cytoplasm

9305:POMT1
gene id: 9305:POMT1
uniprot id: A0A7N4P4L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

9305:PRL
gene id: 9305:PRL
uniprot id: G3VMY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

9305:PTK6
gene id: 9305:PTK6
uniprot id: G3X1S8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9305:STMN4
gene id: 9305:STMN4
uniprot id: A0A7N4NPT2
uniprot id: G3VYK5
names: Similarity
messages: Belongs to the stathmin family.

9305:CASP14
gene id: 9305:CASP14
uniprot id: G3VXC0
names: Similarity
messages: Belongs to the peptidase C14A family.

9305:TMEM170A
gene id: 9305:TMEM170A
uniprot id: A0A7N4PMH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

9305:CKMT2
gene id: 9305:CKMT2
uniprot id: G3WP31
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

9305:FADS6
gene id: 9305:FADS6
uniprot id: G3X3G5
names: Similarity
messages: Belongs to the fatty acid desaturase type 1 family.

9305:COPB1
gene id: 9305:COPB1
uniprot id: G3WSR6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

9305:LOC100914808
gene id: 9305:LOC100914808
uniprot id: A0A7N4PAX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PIR
gene id: 9305:PIR
uniprot id: G3VE48
names: Similarity
messages: Belongs to the pirin family.

9305:RNF40
gene id: 9305:RNF40
uniprot id: G3W7I1
uniprot id: G3W7I2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

9305:TMEM35A
gene id: 9305:TMEM35A
uniprot id: G3WNH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

9305:CAMK1G
gene id: 9305:CAMK1G
uniprot id: A0A7N4NTS5
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:LOC100933087
gene id: 9305:LOC100933087
uniprot id: G3WC35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MGAT1
gene id: 9305:MGAT1
uniprot id: A0A7N4NKK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

9305:CFAP300
gene id: 9305:CFAP300
uniprot id: A0A7N4NV09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

9305:HIGD2A
gene id: 9305:HIGD2A
uniprot id: A0A7N4NVA0
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

9305:EGFL8
gene id: 9305:EGFL8
uniprot id: G3W9E1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:CRABP2
gene id: 9305:CRABP2
uniprot id: A0A7N4V5A7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9305:COX2
gene id: 9305:COX2
uniprot id: G1FKC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9305:BARX1
gene id: 9305:BARX1
uniprot id: A0A7N4PZK1
names: Subcellular Location Annotation
messages: Nucleus

9305:PDCD11
gene id: 9305:PDCD11
uniprot id: G3X1K0
names: Subcellular Location Annotation
messages: nucleolus

9305:NOL6
gene id: 9305:NOL6
uniprot id: A0A7N4P5F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

9305:PUS10
gene id: 9305:PUS10
uniprot id: G3WMA9
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

9305:TAC3
gene id: 9305:TAC3
uniprot id: A0A7N4PXY8
uniprot id: G3VRE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

9305:SLC1A1
gene id: 9305:SLC1A1
uniprot id: G3WGD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9305:SLC5A12
gene id: 9305:SLC5A12
uniprot id: G3W6P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9305:HMX2
gene id: 9305:HMX2
uniprot id: A0A7N4UX19
names: Subcellular Location Annotation
messages: Nucleus

9305:PIK3CG
gene id: 9305:PIK3CG
uniprot id: G3W321
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9305:SEC16B
gene id: 9305:SEC16B
uniprot id: G3WKS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

9305:LOC100917324
gene id: 9305:LOC100917324
uniprot id: G3VZI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ETV6
gene id: 9305:ETV6
uniprot id: G3WQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9305:PRIM1
gene id: 9305:PRIM1
uniprot id: G3VKA9
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

9305:LOC100914459
gene id: 9305:LOC100914459
uniprot id: G3WSL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100921191
gene id: 9305:LOC100921191
uniprot id: A0A7N4V6C7
names: Similarity
messages: Belongs to the SNF7 family.

9305:ENPP3
gene id: 9305:ENPP3
uniprot id: G3W316
names: Subcellular Location Annotation
messages: Secreted

9305:ACTR10
gene id: 9305:ACTR10
uniprot id: A0A7N4P0V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

9305:OAZ3
gene id: 9305:OAZ3
uniprot id: G3WTA5
names: Similarity
messages: Belongs to the ODC antizyme family.

9305:AGRP
gene id: 9305:AGRP
uniprot id: A0A7N4V5E0
uniprot id: G3WKU1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:CDS2
gene id: 9305:CDS2
uniprot id: A0A7N4NKB7
uniprot id: G3WCB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

9305:LOC100921193
gene id: 9305:LOC100921193
uniprot id: G3VUH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:RAD21
gene id: 9305:RAD21
uniprot id: G3WSK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

9305:LOC100929914
gene id: 9305:LOC100929914
uniprot id: G3WJ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:KAT7
gene id: 9305:KAT7
uniprot id: A0A7N4NXQ0
uniprot id: G3W8Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

9305:RFC5
gene id: 9305:RFC5
uniprot id: G3WLM1
names: Similarity
messages: Belongs to the activator 1 small subunits family.

9305:WLS
gene id: 9305:WLS
uniprot id: A0A7N4PIX4
uniprot id: G3WY74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

9305:DGKA
gene id: 9305:DGKA
uniprot id: G3W1Q3
uniprot id: G3W1Q4
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9305:RPAIN
gene id: 9305:RPAIN
uniprot id: G3VGY3
names: Subcellular Location Annotation
messages: Nucleus

9305:SNRPA1
gene id: 9305:SNRPA1
uniprot id: A0A7N4Q0C1
uniprot id: G3VVW4
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

9305:STK11
gene id: 9305:STK11
uniprot id: A0A7N4V6K2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

9305:SPX
gene id: 9305:SPX
uniprot id: A0A7N4PL20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

9305:HPCAL4
gene id: 9305:HPCAL4
uniprot id: A0A7N4PQA4
names: Function
messages: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.

9305:CTSZ
gene id: 9305:CTSZ
uniprot id: A0A7N4NU27
uniprot id: G3WJH4
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Belongs to the peptidase C1 family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

9305:LOC100930845
gene id: 9305:LOC100930845
uniprot id: A0A7N4P221
names: Subcellular Location Annotation
messages: Membrane

9305:EPB42
gene id: 9305:EPB42
uniprot id: G3WE12
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

9305:LOC100922206
gene id: 9305:LOC100922206
uniprot id: A0A7N4P8R7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:DNAAF4
gene id: 9305:DNAAF4
uniprot id: G3W7J6
names: Subcellular Location Annotation
messages: Dynein axonemal particle
messages: neuron projection

9305:UPP2
gene id: 9305:UPP2
uniprot id: G3X0L6
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

9305:C9
gene id: 9305:C9
uniprot id: G3W3E7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted
messages: Target cell membrane

9305:TAS2R40
gene id: 9305:TAS2R40
uniprot id: A0A7N4PBJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9305:LOC100923460
gene id: 9305:LOC100923460
uniprot id: G3WCG3
uniprot id: G3WCQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:POU4F3
gene id: 9305:POU4F3
uniprot id: G3W1P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

9305:TIGD7
gene id: 9305:TIGD7
uniprot id: A0A7N4Q1W2
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100914686
gene id: 9305:LOC100914686
uniprot id: G3W2X3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

9305:APEX1
gene id: 9305:APEX1
uniprot id: G3WKB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

9305:POLH
gene id: 9305:POLH
uniprot id: G3WPK6
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100931087
gene id: 9305:LOC100931087
uniprot id: A0A7N4NS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100918012
gene id: 9305:LOC100918012
uniprot id: A0A7N4NW04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ADAMTS15
gene id: 9305:ADAMTS15
uniprot id: G3WB12
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9305:LOC100928538
gene id: 9305:LOC100928538
uniprot id: A0A7N4V6I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CLIC6
gene id: 9305:CLIC6
uniprot id: A0A7N4PB55
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

9305:BCHE
gene id: 9305:BCHE
uniprot id: G3WUZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

9305:HOXB13
gene id: 9305:HOXB13
uniprot id: G3WJ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9305:CIT
gene id: 9305:CIT
uniprot id: G3X145
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Plays a role in cytokinesis. Displays serine/threonine protein kinase activity.

9305:SLC6A1
gene id: 9305:SLC6A1
uniprot id: G3X151
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9305:GGT6
gene id: 9305:GGT6
uniprot id: A0A7N4PG22
names: Similarity
messages: Belongs to the gamma-glutamyltransferase family.

9305:LOC100924346
gene id: 9305:LOC100924346
uniprot id: G3W5X9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

9305:PROZ
gene id: 9305:PROZ
uniprot id: G3WX86
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:KRT18
gene id: 9305:KRT18
uniprot id: G3VTP8
names: Similarity
messages: Belongs to the intermediate filament family.

9305:POP7
gene id: 9305:POP7
uniprot id: A0A7N4NFT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone-like Alba family.
messages: Component of nuclear RNase P and RNase MRP complexes. RNase P consists of a catalytic RNA moiety and 10 different protein chains; POP1, POP4, POP5, POP7, RPP14, RPP21, RPP25, RPP30, RPP38 and RPP40. Within the RNase P complex, POP1, POP7 and RPP25 form the 'finger' subcomplex, POP5, RPP14, RPP40 and homodimeric RPP30 form the 'palm' subcomplex, and RPP21, POP4 and RPP38 form the 'wrist' subcomplex. All subunits of the RNase P complex interact with the catalytic RNA. Several subunits of RNase P are also part of the RNase MRP complex. RNase MRP consists of a catalytic RNA moiety and about 8 protein subunits; POP1, POP7, RPP25, RPP30, RPP38, RPP40 and possibly also POP4 and POP5. Interacts with SMN1. POP7 forms a heterodimer with RPP25 that binds to the P3 stem loop of the catalytic RNA.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
messages: Cytoplasmic granule
messages: nucleolus

9305:CAVIN1
gene id: 9305:CAVIN1
uniprot id: G3WP13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

9305:SOX8
gene id: 9305:SOX8
uniprot id: A0A7N4NNS4
names: Subcellular Location Annotation
messages: Nucleus

9305:RANGRF
gene id: 9305:RANGRF
uniprot id: A0A7N4P0K4
names: Similarity
messages: Belongs to the MOG1 family.

9305:RTF2
gene id: 9305:RTF2
uniprot id: G3WFW7
names: Similarity
names: Subunit
messages: Belongs to the rtf2 family.
messages: Interacts with DDI2; probably also interacts with DDI1.

9305:SLFN11
gene id: 9305:SLFN11
uniprot id: A0A7N4NM05
names: Similarity
messages: Belongs to the Schlafen family. Subgroup III subfamily.

9305:FGD5
gene id: 9305:FGD5
uniprot id: G3WV35
names: Subcellular Location Annotation
messages: cytoskeleton

9305:TGS1
gene id: 9305:TGS1
uniprot id: A0A7N4V3M7
uniprot id: G3WI36
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

9305:LOC100931214
gene id: 9305:LOC100931214
uniprot id: A0A7N4V631
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Cell membrane
messages: Homodimer.
messages: Membrane

9305:FBLN7
gene id: 9305:FBLN7
uniprot id: G3WTK0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LHPP
gene id: 9305:LHPP
uniprot id: G3VTT2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

9305:CHMP5
gene id: 9305:CHMP5
uniprot id: G3W969
names: Similarity
messages: Belongs to the SNF7 family.

9305:LOC100914388
gene id: 9305:LOC100914388
uniprot id: G3VF83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:EDNRA
gene id: 9305:EDNRA
uniprot id: A0A7N4PYD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

9305:MTERF3
gene id: 9305:MTERF3
uniprot id: G3VRF2
names: Similarity
messages: Belongs to the mTERF family.

9305:PIGC
gene id: 9305:PIGC
uniprot id: A0A7N4NUQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

9305:PCSK6
gene id: 9305:PCSK6
uniprot id: G3VXH5
names: Similarity
messages: Belongs to the peptidase S8 family.

9305:GATB
gene id: 9305:GATB
uniprot id: G3WE99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

9305:PMS2
gene id: 9305:PMS2
uniprot id: G3WLR8
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

9305:ANKRD34C
gene id: 9305:ANKRD34C
uniprot id: A0A7N4PA72
names: Similarity
messages: Belongs to the ANKRD34 family.

9305:EIF3E
gene id: 9305:EIF3E
uniprot id: G3WJ02
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with COPS3, COPS6, COPS7 (COPS7A or COPS7B), EIF4G1, EPAS1, MCM7, NCBP1, PSMC6, TRIM27 and UPF2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Phosphorylated upon DNA damage, probably by ATM or ATR.

9305:MPI
gene id: 9305:MPI
uniprot id: A0A7N4PNY7
uniprot id: G3WTA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

9305:AQP4
gene id: 9305:AQP4
uniprot id: G3WQD1
uniprot id: G3WQD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

9305:GOT1
gene id: 9305:GOT1
uniprot id: G3WLZ6
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

9305:FREM1
gene id: 9305:FREM1
uniprot id: G3WYA2
names: Similarity
messages: Belongs to the FRAS1 family.

9305:SULT4A1
gene id: 9305:SULT4A1
uniprot id: G3VPT7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9305:RNF121
gene id: 9305:RNF121
uniprot id: A0A7N4PUG6
names: Subcellular Location Annotation
messages: Membrane

9305:RPL8
gene id: 9305:RPL8
uniprot id: G3WKH0
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

9305:SPI1
gene id: 9305:SPI1
uniprot id: G3WY81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9305:LOC100919354
gene id: 9305:LOC100919354
uniprot id: A0A7N4P1P0
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:NUP62
gene id: 9305:NUP62
uniprot id: G3VGJ2
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

9305:NR0B2
gene id: 9305:NR0B2
uniprot id: G3WN78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

9305:MOGAT3
gene id: 9305:MOGAT3
uniprot id: G3VHW0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100915707
gene id: 9305:LOC100915707
uniprot id: G3WFD0
names: Subcellular Location Annotation
messages: Membrane

9305:GART
gene id: 9305:GART
uniprot id: G3W376
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

9305:DNAJB14
gene id: 9305:DNAJB14
uniprot id: G3VUI5
names: Subcellular Location Annotation
messages: Membrane

9305:COQ6
gene id: 9305:COQ6
uniprot id: G3VLC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

9305:BORCS7
gene id: 9305:BORCS7
uniprot id: G3X2X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS7 family.
messages: Membrane

9305:NCK1
gene id: 9305:NCK1
uniprot id: G3VW66
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

9305:LOC100921728
gene id: 9305:LOC100921728
uniprot id: G3W1T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LTBP2
gene id: 9305:LTBP2
uniprot id: G3X2N7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9305:SPAG7
gene id: 9305:SPAG7
uniprot id: G3VUS0
names: Subcellular Location Annotation
messages: Nucleus

9305:OPRL1
gene id: 9305:OPRL1
uniprot id: A0A7N4PLR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

9305:F11R
gene id: 9305:F11R
uniprot id: G3WTT4
uniprot id: G3WTT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily.
messages: Cell membrane
messages: Membrane
messages: tight junction

9305:PJVK
gene id: 9305:PJVK
uniprot id: G3W8J0
names: Similarity
messages: Belongs to the gasdermin family.

9305:UCN
gene id: 9305:UCN
uniprot id: G3WJB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

9305:GPR65
gene id: 9305:GPR65
uniprot id: A0A7N4P4C8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:NAPG
gene id: 9305:NAPG
uniprot id: G3WLN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

9305:PMS1
gene id: 9305:PMS1
uniprot id: A0A7N4P7U9
uniprot id: G3WIS0
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

9305:DES
gene id: 9305:DES
uniprot id: G3WHB8
names: Similarity
messages: Belongs to the intermediate filament family.

9305:SPTY2D1
gene id: 9305:SPTY2D1
uniprot id: G3WQN1
names: Similarity
messages: Belongs to the SPT2 family.

9305:CALHM1
gene id: 9305:CALHM1
uniprot id: A0A7N4NU79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9305:SNRPG
gene id: 9305:SNRPG
uniprot id: G3WGG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

9305:TRIM32
gene id: 9305:TRIM32
uniprot id: A0A7N4PNV9
names: Similarity
messages: Belongs to the TRIM/RBCC family.

9305:TUSC3
gene id: 9305:TUSC3
uniprot id: A0A7N4UXF2
uniprot id: G3WTN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:GNPNAT1
gene id: 9305:GNPNAT1
uniprot id: G3VSZ0
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

9305:WSCD2
gene id: 9305:WSCD2
uniprot id: G3WH65
names: Similarity
messages: Belongs to the WSCD family.

9305:LOC100928060
gene id: 9305:LOC100928060
uniprot id: G3W942
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Involved in actively transporting phosphate into cells via Na(+) cotransport.
messages: Membrane

9305:LAMP3
gene id: 9305:LAMP3
uniprot id: G3WUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

9305:COCH
gene id: 9305:COCH
uniprot id: G3WM71
names: Function
messages: Plays a role in the control of cell shape and motility in the trabecular meshwork.

9305:ASIC1
gene id: 9305:ASIC1
uniprot id: A0A7N4PSG6
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100913731
gene id: 9305:LOC100913731
uniprot id: G3WR56
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:GGPS1
gene id: 9305:GGPS1
uniprot id: A0A7N4PBA2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

9305:UCK2
gene id: 9305:UCK2
uniprot id: A0A7N4PHG8
names: Similarity
names: Subunit
messages: Belongs to the uridine kinase family.
messages: Homotetramer.

9305:METTL8
gene id: 9305:METTL8
uniprot id: G3WLY8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

9305:LOC100930974
gene id: 9305:LOC100930974
uniprot id: A0A7N4PX98
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:ANAPC15
gene id: 9305:ANAPC15
uniprot id: G3VII4
names: Similarity
messages: Belongs to the APC15 family.

9305:TMX2
gene id: 9305:TMX2
uniprot id: G3WT70
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity. Indirectly regulates neuronal proliferation, migration, and organization in the developing brain.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

9305:IL18RAP
gene id: 9305:IL18RAP
uniprot id: G3VG70
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9305:THNSL1
gene id: 9305:THNSL1
uniprot id: G3WWT9
names: Similarity
messages: Belongs to the threonine synthase family.

9305:EVC
gene id: 9305:EVC
uniprot id: G3WQS6
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

9305:LOC100913939
gene id: 9305:LOC100913939
uniprot id: G3WEZ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:ATP5F1C
gene id: 9305:ATP5F1C
uniprot id: A0A7N4NZR4
uniprot id: G3X0Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

9305:LOC100925523
gene id: 9305:LOC100925523
uniprot id: G3VK77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100927203
gene id: 9305:LOC100927203
uniprot id: A0A7N4NRA9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9305:LOC100917068
gene id: 9305:LOC100917068
uniprot id: G3VF03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC105750685
gene id: 9305:LOC105750685
uniprot id: A0A7N4PYZ1
names: Similarity
messages: Belongs to the apolipoprotein L family.

9305:CTSH
gene id: 9305:CTSH
uniprot id: A0A7N4PI91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9305:NPHS2
gene id: 9305:NPHS2
uniprot id: G3VVV0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

9305:ADD2
gene id: 9305:ADD2
uniprot id: A0A7N4P9A4
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

9305:GABRB1
gene id: 9305:GABRB1
uniprot id: G3VV14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9305:LOC100920416
gene id: 9305:LOC100920416
uniprot id: G3W6Y3
names: Subcellular Location Annotation
messages: Membrane

9305:EEF2
gene id: 9305:EEF2
uniprot id: G3VZU6
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

9305:CSNK2A1
gene id: 9305:CSNK2A1
uniprot id: G3VX45
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:HMGCR
gene id: 9305:HMGCR
uniprot id: G3VNK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

9305:KCNK10
gene id: 9305:KCNK10
uniprot id: A0A7N4PQZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9305:ENO4
gene id: 9305:ENO4
uniprot id: G3WYH3
names: Similarity
messages: Belongs to the enolase family.

9305:SKA3
gene id: 9305:SKA3
uniprot id: A0A7N4NNC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

9305:TXLNB
gene id: 9305:TXLNB
uniprot id: G3VMC8
names: Similarity
messages: Belongs to the taxilin family.

9305:TASOR2
gene id: 9305:TASOR2
uniprot id: A0A7N4PES4
names: Similarity
messages: Belongs to the TASOR family.

9305:RAB29
gene id: 9305:RAB29
uniprot id: A0A7N4PFZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

9305:NOC3L
gene id: 9305:NOC3L
uniprot id: A0A7N4NGB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: nucleolus

9305:FGF5
gene id: 9305:FGF5
uniprot id: A0A7N4Q153
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heparin-binding growth factors family.
messages: Interacts with FGFR1 and FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
messages: Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.
messages: Secreted

9305:CCN4
gene id: 9305:CCN4
uniprot id: G3WQU8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:POLA1
gene id: 9305:POLA1
uniprot id: G3WJA6
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

9305:LOC100922607
gene id: 9305:LOC100922607
uniprot id: G3WMN8
names: Similarity
messages: Belongs to the cytochrome b5 family.

9305:SPA17
gene id: 9305:SPA17
uniprot id: G3WPY4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.

9305:EXOC2
gene id: 9305:EXOC2
uniprot id: G3VEK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

9305:MRPS5
gene id: 9305:MRPS5
uniprot id: A0A7N4PX94
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

9305:SFXN4
gene id: 9305:SFXN4
uniprot id: A0A7N4PUP8
uniprot id: G3WNZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

9305:LOC100934230
gene id: 9305:LOC100934230
uniprot id: G3WMB8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9305:BMP4
gene id: 9305:BMP4
uniprot id: A0A7N4PDK2
names: Similarity
messages: Belongs to the TGF-beta family.

9305:FAM131B
gene id: 9305:FAM131B
uniprot id: A0A7N4P498
names: Similarity
messages: Belongs to the FAM131 family.

9305:RNASE10
gene id: 9305:RNASE10
uniprot id: G3VKR6
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

9305:FERMT2
gene id: 9305:FERMT2
uniprot id: A0A7N4PSC8
uniprot id: A0A7N4V7E5
names: Similarity
messages: Belongs to the kindlin family.

9305:GSTZ1
gene id: 9305:GSTZ1
uniprot id: A0A7N4V464
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

9305:LOC100919283
gene id: 9305:LOC100919283
uniprot id: A0A7N4PPN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ENKD1
gene id: 9305:ENKD1
uniprot id: A0A7N4V7K5
uniprot id: G3VRK7
names: Subcellular Location Annotation
messages: cilium axoneme

9305:GNGT1
gene id: 9305:GNGT1
uniprot id: A0A7N4PGQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9305:TACR3
gene id: 9305:TACR3
uniprot id: G3VD07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ERCC3
gene id: 9305:ERCC3
uniprot id: G3VZG5
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

9305:HTR1D
gene id: 9305:HTR1D
uniprot id: A0A7N4P594
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1B.
messages: Membrane

9305:NMNAT1
gene id: 9305:NMNAT1
uniprot id: G3W9B6
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

9305:DCST2
gene id: 9305:DCST2
uniprot id: G3VSF8
names: Subcellular Location Annotation
messages: Membrane

9305:ENO2
gene id: 9305:ENO2
uniprot id: A0A7N4V3Q1
uniprot id: G3WUN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

9305:LOC100917935
gene id: 9305:LOC100917935
uniprot id: A0A7N4PST4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:FAM161B
gene id: 9305:FAM161B
uniprot id: G3VMX1
names: Similarity
messages: Belongs to the FAM161 family.

9305:MDM4
gene id: 9305:MDM4
uniprot id: A0A7N4NG55
uniprot id: G3W0L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

9305:LOC100924004
gene id: 9305:LOC100924004
uniprot id: G3X0E0
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:NIPAL2
gene id: 9305:NIPAL2
uniprot id: G3VNB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9305:LOC100932237
gene id: 9305:LOC100932237
uniprot id: A0A7N4PJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:HTRA4
gene id: 9305:HTRA4
uniprot id: G3X2G8
names: Similarity
messages: Belongs to the peptidase S1C family.

9305:LOC100918920
gene id: 9305:LOC100918920
uniprot id: A0A7N4V3E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CCDC172
gene id: 9305:CCDC172
uniprot id: G3VA37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC172 family.
messages: Cytoplasm

9305:STARD13
gene id: 9305:STARD13
uniprot id: A0A7N4Q0B1
uniprot id: G3VV03
names: Subcellular Location Annotation
messages: Cytoplasm

9305:FGD3
gene id: 9305:FGD3
uniprot id: G3WXE9
names: Subcellular Location Annotation
messages: cytoskeleton

9305:SLC39A5
gene id: 9305:SLC39A5
uniprot id: G3VH54
names: Subcellular Location Annotation
messages: Membrane

9305:MINAR1
gene id: 9305:MINAR1
uniprot id: A0A7N4NWY2
uniprot id: G3VE22
names: Similarity
messages: Belongs to the MINAR family.

9305:LOC100925942
gene id: 9305:LOC100925942
uniprot id: G3VJL7
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

9305:PYCR2
gene id: 9305:PYCR2
uniprot id: G3WN62
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

9305:MEIG1
gene id: 9305:MEIG1
uniprot id: A0A7N4PBC7
names: Function
names: Similarity
messages: Belongs to the MEIG1 family.
messages: Essential for spermiogenesis.

9305:LOC100915753
gene id: 9305:LOC100915753
uniprot id: G3VFC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TASP1
gene id: 9305:TASP1
uniprot id: A0A7N4P650
uniprot id: G3VRT7
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

9305:NOG
gene id: 9305:NOG
uniprot id: A0A7N4NWG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
messages: Secreted

9305:KATNAL1
gene id: 9305:KATNAL1
uniprot id: A0A7N4PYR2
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and DCAF1 proteins (EDVP complex). Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42. Interacts with KATNB1 and KATNBL1. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: Cytoplasm
messages: Interacts with KATNB1 and KATNBL1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Midbody
messages: Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation.
messages: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays.
messages: The N-terminus is sufficient for interaction with microtubules, although high affinity binding to microtubules also requires an intact C-terminal domain and ATP, which promotes oligomerization.
messages: Ubiquitinated by the BCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation. Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted for proteasomal degradation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

9305:RCAN3
gene id: 9305:RCAN3
uniprot id: A0A7N4NXJ6
names: Similarity
messages: Belongs to the RCAN family.

9305:LOC100927849
gene id: 9305:LOC100927849
uniprot id: G3WGY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:GUCY2D
gene id: 9305:GUCY2D
uniprot id: G3WLS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

9305:LOC100924758
gene id: 9305:LOC100924758
uniprot id: G3VEZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:NEU1
gene id: 9305:NEU1
uniprot id: A0A7N4PBU0
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

9305:PSMB7
gene id: 9305:PSMB7
uniprot id: G3WU12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is a barrel-shaped complex made of 28 subunits that are arranged in four stacked rings. The two outer rings are each formed by seven alpha subunits, and the two inner rings are formed by seven beta subunits. The proteolytic activity is exerted by three beta-subunits PSMB5, PSMB6 and PSMB7.

9305:FAM110C
gene id: 9305:FAM110C
uniprot id: A0A7N4V5P5
names: Similarity
messages: Belongs to the FAM110 family.

9305:LOC100917407
gene id: 9305:LOC100917407
uniprot id: G3W0T0
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:SHOC2
gene id: 9305:SHOC2
uniprot id: G3WBX1
names: Function
names: Similarity
messages: Belongs to the SHOC2 family.
messages: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

9305:TYRP1
gene id: 9305:TYRP1
uniprot id: G3VZQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

9305:ZFPL1
gene id: 9305:ZFPL1
uniprot id: G3VGE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZFPL1 family.
messages: Interacts with GOLGA2/GM130.
messages: Membrane
messages: Required for cis-Golgi integrity and efficient ER to Golgi transport.
messages: The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.
messages: cis-Golgi network membrane

9305:LGI3
gene id: 9305:LGI3
uniprot id: A0A7N4P1W3
uniprot id: G3X116
names: Subcellular Location Annotation
messages: Secreted

9305:ZER1
gene id: 9305:ZER1
uniprot id: A0A7N4UXJ5
names: Similarity
messages: Belongs to the zyg-11 family.

9305:EXO1
gene id: 9305:EXO1
uniprot id: G3W8T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

9305:TLX2
gene id: 9305:TLX2
uniprot id: A0A7N4NQ75
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100921941
gene id: 9305:LOC100921941
uniprot id: G3VUD7
names: Caution
names: Similarity
messages: Belongs to the FXYD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100918326
gene id: 9305:LOC100918326
uniprot id: G3W9C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TOR4A
gene id: 9305:TOR4A
uniprot id: A0A7N4NSZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Membrane

9305:F2R
gene id: 9305:F2R
uniprot id: G3W599
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ATAD1
gene id: 9305:ATAD1
uniprot id: G3VTP7
names: Similarity
messages: Belongs to the AAA ATPase family.

9305:TIMM44
gene id: 9305:TIMM44
uniprot id: A0A7N4UXV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

9305:CCDC153
gene id: 9305:CCDC153
uniprot id: G3W503
names: Similarity
messages: Belongs to the UPF0610 family.

9305:MRPL33
gene id: 9305:MRPL33
uniprot id: A0A7N4PUY1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

9305:GCM1
gene id: 9305:GCM1
uniprot id: G3WTH9
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100923003
gene id: 9305:LOC100923003
uniprot id: G3VKC5
names: Similarity
messages: Belongs to the MHC class II family.

9305:SEMA3F
gene id: 9305:SEMA3F
uniprot id: G3X247
uniprot id: G3X248
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:SERPINF1
gene id: 9305:SERPINF1
uniprot id: G3VZE9
names: Similarity
messages: Belongs to the serpin family.

9305:LOC100916836
gene id: 9305:LOC100916836
uniprot id: G3WB26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9305:LOC100934578
gene id: 9305:LOC100934578
uniprot id: G3VVM9
names: Similarity
messages: Belongs to the FAM10 family.

9305:PTPA
gene id: 9305:PTPA
uniprot id: G3VB41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9305:RPL26
gene id: 9305:RPL26
uniprot id: G3WCU1
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

9305:LOC100928906
gene id: 9305:LOC100928906
uniprot id: G3VGC5
names: Similarity
messages: Belongs to the MHC class I family.

9305:LOC100928229
gene id: 9305:LOC100928229
uniprot id: G3VSW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:KRT7
gene id: 9305:KRT7
uniprot id: G3WL72
names: Similarity
messages: Belongs to the intermediate filament family.

9305:LOC100919827
gene id: 9305:LOC100919827
uniprot id: G3W7W1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9305:GABBR1
gene id: 9305:GABBR1
uniprot id: G3VPG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

9305:SFTPC
gene id: 9305:SFTPC
uniprot id: G3X147
names: Function
names: Subcellular Location Annotation
messages: Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
messages: surface film

9305:ST3GAL4
gene id: 9305:ST3GAL4
uniprot id: G3VC60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9305:DAO
gene id: 9305:DAO
uniprot id: G3WF43
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

9305:PFDN1
gene id: 9305:PFDN1
uniprot id: G3WS10
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

9305:PRR5L
gene id: 9305:PRR5L
uniprot id: A0A7N4PY72
names: Similarity
messages: Belongs to the PROTOR family.

9305:SNAP25
gene id: 9305:SNAP25
uniprot id: G3VSV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A; this complex binds CPLX1. Found in a complex containing SYT1, SV2B and syntaxin-1. Found in a ternary complex with STX1A and VAMP8. Interacts with HSC70 and with SYT9, forming a complex with DNAJC5. The interaction with SYT9 is inhibited in presence of calcium. Isoform 1 and isoform 2 interact with BLOC1S6. Interacts with CENPF. Interacts with EQTN. Interacts with HGS. Interacts with KCNB1 (via N-terminus); reduces the voltage-dependent potassium channel KCNB1 activity in pancreatic beta cells. Interacts with OTOF. Interacts with RIMS1. Interacts with SNAPIN. Interacts with STXBP6. Interacts with TRIM9. Interacts with ZDHHC13 (via ANK repeats). Interacts with ZDHHC17 (via ANK repeats). Associates with the BLOC-1 complex. Interacts with PLCL1 (via C2 domain). Interacts with PRRT2; this interaction may impair the formation of the SNARE complex. Interacts with alpha-synuclein/SNCA. Interacts with PRPH2. Interacts with ROM1. Interacts with STX3.
messages: Photoreceptor inner segment
messages: synaptosome
messages: t-SNARE involved in the molecular regulation of neurotransmitter release. Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.

9305:GPR25
gene id: 9305:GPR25
uniprot id: A0A7N4V3Z4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:HOPX
gene id: 9305:HOPX
uniprot id: A0A7N4UZ80
names: Subcellular Location Annotation
messages: Nucleus

9305:ATP10B
gene id: 9305:ATP10B
uniprot id: A0A7N4PR68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9305:LOC100932138
gene id: 9305:LOC100932138
uniprot id: A0A7N4PWM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:FLVCR2
gene id: 9305:FLVCR2
uniprot id: G3WWV1
names: Subcellular Location Annotation
messages: Membrane

9305:ATP6AP2
gene id: 9305:ATP6AP2
uniprot id: G3VTN1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

9305:NPY1R
gene id: 9305:NPY1R
uniprot id: A0A7N4P4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MYOD1
gene id: 9305:MYOD1
uniprot id: G3WXZ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

9305:LSM8
gene id: 9305:LSM8
uniprot id: A0A7N4P707
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

9305:PDCL2
gene id: 9305:PDCL2
uniprot id: A0A7N4PG10
names: Similarity
messages: Belongs to the phosducin family.

9305:LOC100925080
gene id: 9305:LOC100925080
uniprot id: A0A7N4NU63
names: Subcellular Location Annotation
messages: Membrane

9305:NDNF
gene id: 9305:NDNF
uniprot id: G3W1T7
names: Subcellular Location Annotation
messages: Secreted

9305:C2H9orf116
gene id: 9305:C2H9orf116
uniprot id: A0A7N4PPP2
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CFAP53, ODAD1 and ODAD3; the interactions link the outer dynein arms docking complex (ODA-DC) to the internal microtubule inner proteins (MIP) in cilium axoneme.
messages: cilium axoneme

9305:NDUFS7
gene id: 9305:NDUFS7
uniprot id: G3WLN5
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

9305:FAM149B1
gene id: 9305:FAM149B1
uniprot id: G3VKS0
names: Similarity
messages: Belongs to the FAM149 family.

9305:GPN3
gene id: 9305:GPN3
uniprot id: A0A7N4V7U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

9305:LOC100918458
gene id: 9305:LOC100918458
uniprot id: G3VXY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100924360
gene id: 9305:LOC100924360
uniprot id: A0A7N4NZX1
names: Subcellular Location Annotation
messages: Membrane

9305:PDCD4
gene id: 9305:PDCD4
uniprot id: A0A7N4PLI6
uniprot id: G3WFA5
names: Similarity
messages: Belongs to the PDCD4 family.

9305:CFAP97D2
gene id: 9305:CFAP97D2
uniprot id: A0A7N4NJ61
names: Similarity
messages: Belongs to the CFAP97 family.

9305:IGF1
gene id: 9305:IGF1
uniprot id: A0A7N4P467
uniprot id: A0A7N4V731
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

9305:STK40
gene id: 9305:STK40
uniprot id: A0A7N4PHM4
uniprot id: G3X0L0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

9305:TMEM254
gene id: 9305:TMEM254
uniprot id: G3VUF3
names: Subcellular Location Annotation
messages: Membrane

9305:AQP3
gene id: 9305:AQP3
uniprot id: G3VKB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9305:NIM1K
gene id: 9305:NIM1K
uniprot id: G3WBK1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:CBLIF
gene id: 9305:CBLIF
uniprot id: A0A7N4PCH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

9305:CDX1
gene id: 9305:CDX1
uniprot id: A0A7N4PHY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

9305:LOC105750241
gene id: 9305:LOC105750241
uniprot id: G3WY07
names: Similarity
messages: Belongs to the MHC class I family.

9305:PHKG1
gene id: 9305:PHKG1
uniprot id: A0A7N4PKG8
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

9305:HIBCH
gene id: 9305:HIBCH
uniprot id: G3WP61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

9305:HINT1
gene id: 9305:HINT1
uniprot id: A0A7N4NG49
names: Similarity
messages: Belongs to the HINT family.

9305:JAG2
gene id: 9305:JAG2
uniprot id: G3VAT1
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

9305:TOX4
gene id: 9305:TOX4
uniprot id: A0A7N4NW66
uniprot id: G3W4A0
names: Subcellular Location Annotation
messages: Nucleus

9305:NETO1
gene id: 9305:NETO1
uniprot id: G3VFF1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:NLE1
gene id: 9305:NLE1
uniprot id: G3VN49
names: Subcellular Location Annotation
messages: nucleolus

9305:LMX1A
gene id: 9305:LMX1A
uniprot id: G3WNU7
names: Subcellular Location Annotation
messages: Nucleus

9305:NGFR
gene id: 9305:NGFR
uniprot id: G3VV93
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100927938
gene id: 9305:LOC100927938
uniprot id: G3VYM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:RAB9A
gene id: 9305:RAB9A
uniprot id: A0A7N4PQW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: phagosome membrane

9305:CCDC65
gene id: 9305:CCDC65
uniprot id: A0A7N4PKR0
names: Subcellular Location Annotation
names: Subunit
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: flagellum axoneme

9305:DIPK1C
gene id: 9305:DIPK1C
uniprot id: G3W4A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

9305:HPGD
gene id: 9305:HPGD
uniprot id: G3W470
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9305:LOC100916478
gene id: 9305:LOC100916478
uniprot id: A0A7N4PFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9305:LOC100914095
gene id: 9305:LOC100914095
uniprot id: A0A7N4UZN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CNRIP1
gene id: 9305:CNRIP1
uniprot id: A0A7N4PL24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

9305:PFDN4
gene id: 9305:PFDN4
uniprot id: A0A7N4NNE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

9305:MC4R
gene id: 9305:MC4R
uniprot id: G3VTY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

9305:SPATA6L
gene id: 9305:SPATA6L
uniprot id: G3WIC2
names: Similarity
messages: Belongs to the SPATA6 family.

9305:POLR2M
gene id: 9305:POLR2M
uniprot id: G3WLU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRINL1 family.
messages: Nucleus

9305:LOC100919403
gene id: 9305:LOC100919403
uniprot id: A0A7N4PPT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

9305:POLE
gene id: 9305:POLE
uniprot id: G3W6W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

9305:FAM136A
gene id: 9305:FAM136A
uniprot id: G3WG72
names: Similarity
messages: Belongs to the FAM136 family.

9305:PYROXD1
gene id: 9305:PYROXD1
uniprot id: G3WTG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: sarcomere

9305:ARSF
gene id: 9305:ARSF
uniprot id: G3W030
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9305:ELOC
gene id: 9305:ELOC
uniprot id: G3W849
names: Similarity
messages: Belongs to the SKP1 family.

9305:NRN1L
gene id: 9305:NRN1L
uniprot id: A0A7N4P348
names: Similarity
messages: Belongs to the neuritin family.

9305:LEPROTL1
gene id: 9305:LEPROTL1
uniprot id: G3WEN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

9305:LOC100920499
gene id: 9305:LOC100920499
uniprot id: G3WZY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9305:PRPF18
gene id: 9305:PRPF18
uniprot id: A0A7N4NVR8
uniprot id: G3WVC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

9305:VCAN
gene id: 9305:VCAN
uniprot id: G3VZ56
names: Caution
names: Similarity
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:DRC7
gene id: 9305:DRC7
uniprot id: G3VWX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC7 family.
messages: cilium axoneme
messages: flagellum
messages: flagellum axoneme

9305:ARAP3
gene id: 9305:ARAP3
uniprot id: A0A7N4V1X3
names: Subcellular Location Annotation
messages: Cytoplasm

9305:MSH5
gene id: 9305:MSH5
uniprot id: G3VWQ2
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

9305:SDC4
gene id: 9305:SDC4
uniprot id: G3WKH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

9305:RARS1
gene id: 9305:RARS1
uniprot id: A0A7N4V1A1
uniprot id: G3WRU8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9305:MTX3
gene id: 9305:MTX3
uniprot id: A0A7N4NPW4
uniprot id: G3WBN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

9305:LOC100915226
gene id: 9305:LOC100915226
uniprot id: G3WPS0
uniprot id: G3WPS1
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

9305:DICER1
gene id: 9305:DICER1
uniprot id: G3WFC6
names: Function
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.
messages: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

9305:SPPL2B
gene id: 9305:SPPL2B
uniprot id: G3VS63
uniprot id: G3VS64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

9305:GALC
gene id: 9305:GALC
uniprot id: G3VEU4
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

9305:DDC
gene id: 9305:DDC
uniprot id: G3WV06
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9305:ADCYAP1
gene id: 9305:ADCYAP1
uniprot id: A0A7N4PDL1
uniprot id: G3VZU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucagon family.
messages: Interacts with ADCYAP1R1 (via N-terminal extracellular domain).
messages: Secreted

9305:TRIM54
gene id: 9305:TRIM54
uniprot id: G3WIP5
names: Function
names: Subcellular Location Annotation
messages: May bind and stabilize microtubules during myotubes formation.
messages: Z line

9305:F12
gene id: 9305:F12
uniprot id: G3WPF1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:SMARCA2
gene id: 9305:SMARCA2
uniprot id: G3W0Z6
uniprot id: G3W0Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

9305:PROKR1
gene id: 9305:PROKR1
uniprot id: A0A7N4NPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9305:TERF2IP
gene id: 9305:TERF2IP
uniprot id: G3VIQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Nucleus
messages: telomere

9305:LOC100914875
gene id: 9305:LOC100914875
uniprot id: G3VEJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ESRRG
gene id: 9305:ESRRG
uniprot id: A0A7N4NI24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9305:SLC17A8
gene id: 9305:SLC17A8
uniprot id: G3WDI0
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100916503
gene id: 9305:LOC100916503
uniprot id: G3VFG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.

9305:SLC44A2
gene id: 9305:SLC44A2
uniprot id: A0A7N4NJJ1
uniprot id: G3VP50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

9305:SERPINI2
gene id: 9305:SERPINI2
uniprot id: G3W2E9
names: Similarity
messages: Belongs to the serpin family.

9305:LOC100929496
gene id: 9305:LOC100929496
uniprot id: A0A7N4P994
names: Similarity
messages: Belongs to the intermediate filament family.

9305:SLC18A2
gene id: 9305:SLC18A2
uniprot id: G3WVI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

9305:GDAP1L1
gene id: 9305:GDAP1L1
uniprot id: G3VSU6
names: Similarity
messages: Belongs to the GST superfamily.

9305:SLC16A1
gene id: 9305:SLC16A1
uniprot id: A0A7N4PY36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

9305:IAH1
gene id: 9305:IAH1
uniprot id: G3VXB7
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

9305:C1H18orf21
gene id: 9305:C1H18orf21
uniprot id: A0A7N4Q137
names: Similarity
messages: Belongs to the UPF0711 family.

9305:PRKAA1
gene id: 9305:PRKAA1
uniprot id: A0A7N4PKM2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

9305:LOC100935068
gene id: 9305:LOC100935068
uniprot id: A0A076G1J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-2 family.
messages: Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance. Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG). Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3. In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5. This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways. Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well. Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production. Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance. Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells.
messages: Secreted

9305:C3AR1
gene id: 9305:C3AR1
uniprot id: A0A7N4NGB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with VGF-derived peptide TLQP-21.
messages: Membrane
messages: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

9305:WASF2
gene id: 9305:WASF2
uniprot id: G3VQY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

9305:TEF
gene id: 9305:TEF
uniprot id: A0A7N4P9I4
uniprot id: G3W605
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

9305:LOC100915113
gene id: 9305:LOC100915113
uniprot id: G3VY30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TMA16
gene id: 9305:TMA16
uniprot id: A0A7N4PDI2
uniprot id: G3WTS3
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

9305:LIG4
gene id: 9305:LIG4
uniprot id: A0A7N4NYN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

9305:OGDH
gene id: 9305:OGDH
uniprot id: A0A7N4NTG9
uniprot id: A0A7N4PJA4
uniprot id: G3WW88
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

9305:KCNB2
gene id: 9305:KCNB2
uniprot id: A0A7N4NII8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon

9305:PRMT7
gene id: 9305:PRMT7
uniprot id: G3VT19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

9305:MEAF6
gene id: 9305:MEAF6
uniprot id: A0A7N4PFQ7
uniprot id: G3WES0
uniprot id: G3WES1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

9305:LETMD1
gene id: 9305:LETMD1
uniprot id: G3VIF6
names: Subcellular Location Annotation
messages: Membrane

9305:CALR
gene id: 9305:CALR
uniprot id: A0A7N4PYZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen
messages: Monomer.

9305:CAPN7
gene id: 9305:CAPN7
uniprot id: G3VKK8
names: Similarity
messages: Belongs to the peptidase C2 family.

9305:SLC1A3
gene id: 9305:SLC1A3
uniprot id: A0A7N4PK04
uniprot id: G3X2J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9305:CWC15
gene id: 9305:CWC15
uniprot id: G3WVL5
names: Similarity
messages: Belongs to the CWC15 family.

9305:ISL1
gene id: 9305:ISL1
uniprot id: G3WAC9
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100930173
gene id: 9305:LOC100930173
uniprot id: G3WJN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ORC5
gene id: 9305:ORC5
uniprot id: A0A7N4PJ88
names: Subcellular Location Annotation
messages: Nucleus

9305:CHRNA7
gene id: 9305:CHRNA7
uniprot id: G3WE61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9305:LOC100930819
gene id: 9305:LOC100930819
uniprot id: A0A7N4PGA2
names: Subcellular Location Annotation
messages: Membrane

9305:CLDN7
gene id: 9305:CLDN7
uniprot id: A0A7N4PLS7
uniprot id: G3W1I6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9305:PITX1
gene id: 9305:PITX1
uniprot id: G3WK78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9305:MDFI
gene id: 9305:MDFI
uniprot id: G3W329
names: Similarity
messages: Belongs to the MDFI family.

9305:UBA7
gene id: 9305:UBA7
uniprot id: G3X040
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

9305:LOC100933622
gene id: 9305:LOC100933622
uniprot id: G3WNM9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9305:PIGF
gene id: 9305:PIGF
uniprot id: G3W9U0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:LOC100922680
gene id: 9305:LOC100922680
uniprot id: G3VZ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:SHC1
gene id: 9305:SHC1
uniprot id: G3VPR5
names: Subcellular Location Annotation
messages: Cytoplasm

9305:PCMTD2
gene id: 9305:PCMTD2
uniprot id: A0A7N4PVS3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

9305:DACT2
gene id: 9305:DACT2
uniprot id: A0A7N4NY91
names: Similarity
messages: Belongs to the dapper family.

9305:LSM6
gene id: 9305:LSM6
uniprot id: A0A7N4NY59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

9305:LOC100916119
gene id: 9305:LOC100916119
uniprot id: G3VEY5
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

9305:HBZ
gene id: 9305:HBZ
uniprot id: A0A7N4PK19
uniprot id: G3WDN9
names: Similarity
messages: Belongs to the globin family.

9305:PDGFRA
gene id: 9305:PDGFRA
uniprot id: A0A7N4NXR5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Interacts with homodimeric PDGFA, PDGFB and PDGFC, and with heterodimers formed by PDGFA and PDGFB. Monomer in the absence of bound ligand.
messages: Membrane
messages: Present in an inactive conformation in the absence of bound ligand. Binding of PDGFA and/or PDGFB leads to dimerization and activation by autophosphorylation on tyrosine residues.
messages: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.

9305:STX1B
gene id: 9305:STX1B
uniprot id: A0A7N4V672
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

9305:MGAT5B
gene id: 9305:MGAT5B
uniprot id: G3VDS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:CLPTM1L
gene id: 9305:CLPTM1L
uniprot id: A0A7N4NPP1
uniprot id: G3WU60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

9305:PCOLCE2
gene id: 9305:PCOLCE2
uniprot id: G3WQ65
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:LOC100929747
gene id: 9305:LOC100929747
uniprot id: G3VVD9
names: Similarity
messages: Belongs to the intermediate filament family.

9305:LOC100917092
gene id: 9305:LOC100917092
uniprot id: G3VC51
names: Subcellular Location Annotation
messages: Membrane

9305:GABRG2
gene id: 9305:GABRG2
uniprot id: A0A7N4NKV0
uniprot id: G3VM85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9305:LOC100934869
gene id: 9305:LOC100934869
uniprot id: A0A7N4PC09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

9305:LOC100922418
gene id: 9305:LOC100922418
uniprot id: A0A7N4PUL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ACVR1
gene id: 9305:ACVR1
uniprot id: G3WYP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9305:RPL29
gene id: 9305:RPL29
uniprot id: G3VXJ3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

9305:LOC100913541
gene id: 9305:LOC100913541
uniprot id: A0A7N4PYE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MOGAT1
gene id: 9305:MOGAT1
uniprot id: A0A7N4PH48
uniprot id: G3WSI8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:MED18
gene id: 9305:MED18
uniprot id: A0A7N4PDN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9305:KCNA4
gene id: 9305:KCNA4
uniprot id: A0A7N4PNM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

9305:LOC100930076
gene id: 9305:LOC100930076
uniprot id: G3VX84
names: Subcellular Location Annotation
messages: Membrane

9305:ICAM2
gene id: 9305:ICAM2
uniprot id: A0A7N4NHF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

9305:XPA
gene id: 9305:XPA
uniprot id: G3WTQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

9305:CD36
gene id: 9305:CD36
uniprot id: G3W326
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the CD36 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: Membrane raft

9305:HMGB3
gene id: 9305:HMGB3
uniprot id: A0A7N4PCH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

9305:MANEAL
gene id: 9305:MANEAL
uniprot id: G3WLP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:FUCA2
gene id: 9305:FUCA2
uniprot id: G3WL20
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

9305:TSPAN7
gene id: 9305:TSPAN7
uniprot id: G3WHB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9305:LHX3
gene id: 9305:LHX3
uniprot id: G3WDD4
names: Subcellular Location Annotation
messages: Nucleus

9305:MSANTD3
gene id: 9305:MSANTD3
uniprot id: A0A7N4NSQ2
names: Similarity
messages: Belongs to the MSANTD3 family.

9305:BMP10
gene id: 9305:BMP10
uniprot id: G3W835
names: Similarity
messages: Belongs to the TGF-beta family.

9305:TUBB6
gene id: 9305:TUBB6
uniprot id: G3VXT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9305:LRRC8A
gene id: 9305:LRRC8A
uniprot id: G3X3Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9305:LOC100919063
gene id: 9305:LOC100919063
uniprot id: A0A7N4NZE8
uniprot id: G3WSP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

9305:EML4
gene id: 9305:EML4
uniprot id: G3WFN5
names: Similarity
messages: Belongs to the WD repeat EMAP family.

9305:ACKR1
gene id: 9305:ACKR1
uniprot id: A0A7N4UY62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1 and TARC. May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels.
messages: Belongs to the G-protein coupled receptor 1 family. Atypical chemokine receptor subfamily.
messages: Early endosome
messages: Membrane
messages: Recycling endosome

9305:DYNLRB1
gene id: 9305:DYNLRB1
uniprot id: A0A7N4NI06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer.
messages: cytoskeleton

9305:IK
gene id: 9305:IK
uniprot id: G3WV90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RED family.
messages: Nucleus

9305:TGM1
gene id: 9305:TGM1
uniprot id: G3VPQ0
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9305:PBX2
gene id: 9305:PBX2
uniprot id: A0A7N4NXG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

9305:LOC100931906
gene id: 9305:LOC100931906
uniprot id: G3W997
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:DYNLT3
gene id: 9305:DYNLT3
uniprot id: A0A7N4UZL1
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9305:ATG7
gene id: 9305:ATG7
uniprot id: G3X2I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress.
messages: Homodimer.
messages: Preautophagosomal structure

9305:LEPR
gene id: 9305:LEPR
uniprot id: G3WA33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

9305:RPL36
gene id: 9305:RPL36
uniprot id: G3WK82
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

9305:EIF3M
gene id: 9305:EIF3M
uniprot id: G3WZE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

9305:SGTA
gene id: 9305:SGTA
uniprot id: G3WEQ9
names: Similarity
messages: Belongs to the SGT family.

9305:RPS6KA2
gene id: 9305:RPS6KA2
uniprot id: G3VW05
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

9305:FZD6
gene id: 9305:FZD6
uniprot id: G3VPF7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:BCKDK
gene id: 9305:BCKDK
uniprot id: G3WE42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

9305:LOC100935147
gene id: 9305:LOC100935147
uniprot id: G3VBV2
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9305:LOC100915997
gene id: 9305:LOC100915997
uniprot id: A0A7N4PSU1
names: Similarity
messages: Belongs to the serpin family.

9305:CHIT1
gene id: 9305:CHIT1
uniprot id: G3WWC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

9305:CSTF1
gene id: 9305:CSTF1
uniprot id: G3WIW8
names: Subcellular Location Annotation
messages: Nucleus

9305:SLITRK6
gene id: 9305:SLITRK6
uniprot id: A0A7N4NU28
names: Similarity
messages: Belongs to the SLITRK family.

9305:LOC100921839
gene id: 9305:LOC100921839
uniprot id: G3W844
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9305:TAGLN
gene id: 9305:TAGLN
uniprot id: G3WC56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calponin family.
messages: Cytoplasm

9305:RAB14
gene id: 9305:RAB14
uniprot id: G3WZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

9305:PHC3
gene id: 9305:PHC3
uniprot id: G3WRG7
names: Subcellular Location Annotation
messages: Nucleus

9305:NSUN6
gene id: 9305:NSUN6
uniprot id: G3W2F4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:RRP1B
gene id: 9305:RRP1B
uniprot id: G3WZX4
names: Similarity
messages: Belongs to the RRP1 family.

9305:LOC100921717
gene id: 9305:LOC100921717
uniprot id: G3W0U7
names: Similarity
messages: Belongs to the Toll-like receptor family.

9305:ENTPD1
gene id: 9305:ENTPD1
uniprot id: G3W8B3
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9305:ST14
gene id: 9305:ST14
uniprot id: G3W452
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:LOC100920805
gene id: 9305:LOC100920805
uniprot id: G3W397
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:HSPA13
gene id: 9305:HSPA13
uniprot id: G3VJF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Binds UBQLN2.
messages: Endoplasmic reticulum
messages: Has peptide-independent ATPase activity.
messages: Microsome

9305:DDX6
gene id: 9305:DDX6
uniprot id: A0A7N4NJ88
uniprot id: G3WD54
names: Similarity
messages: Belongs to the DEAD box helicase family.

9305:LARS1
gene id: 9305:LARS1
uniprot id: A0A7N4PVK2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9305:IL21
gene id: 9305:IL21
uniprot id: A0A7N4PK96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

9305:F7
gene id: 9305:F7
uniprot id: G3WY11
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:ST6GALNAC4
gene id: 9305:ST6GALNAC4
uniprot id: G3X2C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9305:LOC100930214
gene id: 9305:LOC100930214
uniprot id: G3W6R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LAPTM5
gene id: 9305:LAPTM5
uniprot id: G3WJE8
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

9305:EPN3
gene id: 9305:EPN3
uniprot id: A0A7N4P0K6
uniprot id: G3VQA4
names: Similarity
messages: Belongs to the epsin family.

9305:LOC100924990
gene id: 9305:LOC100924990
uniprot id: G3VVW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9305:NDUFS5
gene id: 9305:NDUFS5
uniprot id: G3WYW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

9305:ND5
gene id: 9305:ND5
uniprot id: J9S3Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

9305:KCNJ11
gene id: 9305:KCNJ11
uniprot id: A0A7N4PJB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

9305:KCNV1
gene id: 9305:KCNV1
uniprot id: A0A7N4PAT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
messages: Heteromultimer with KCNB1 and KCNB2. Interacts with KCNC4 and KCND1.
messages: Membrane
messages: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.

9305:GPRC5B
gene id: 9305:GPRC5B
uniprot id: A0A7N4NZ94
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:ACSM5
gene id: 9305:ACSM5
uniprot id: G3X3T1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9305:GUCA2B
gene id: 9305:GUCA2B
uniprot id: G3WEU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

9305:CLDN17
gene id: 9305:CLDN17
uniprot id: G3WHJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9305:PRKAR2A
gene id: 9305:PRKAR2A
uniprot id: A0A7N4NNT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

9305:XRCC6
gene id: 9305:XRCC6
uniprot id: G3WB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus

9305:SLC40A1
gene id: 9305:SLC40A1
uniprot id: G3WCX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

9305:PLSCR5
gene id: 9305:PLSCR5
uniprot id: G3WXE2
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

9305:TMEM229B
gene id: 9305:TMEM229B
uniprot id: A0A7N4Q1A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

9305:ADGRG1
gene id: 9305:ADGRG1
uniprot id: G3VRU6
uniprot id: G3VRU7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Secreted

9305:TECR
gene id: 9305:TECR
uniprot id: G3VD97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:DDO
gene id: 9305:DDO
uniprot id: G3VH80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

9305:OPLAH
gene id: 9305:OPLAH
uniprot id: G3VND4
names: Similarity
messages: Belongs to the oxoprolinase family.

9305:CIBAR2
gene id: 9305:CIBAR2
uniprot id: G3WBY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

9305:UFL1
gene id: 9305:UFL1
uniprot id: A0A7N4PMC6
names: Similarity
messages: Belongs to the UFL1 family.

9305:ADA
gene id: 9305:ADA
uniprot id: G3W4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

9305:MMP27
gene id: 9305:MMP27
uniprot id: G3WLF4
names: Similarity
messages: Belongs to the peptidase M10A family.

9305:MRPS15
gene id: 9305:MRPS15
uniprot id: G3X124
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

9305:MARCO
gene id: 9305:MARCO
uniprot id: G3WYB9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:HESX1
gene id: 9305:HESX1
uniprot id: G3WGR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

9305:LOC100918178
gene id: 9305:LOC100918178
uniprot id: A0A7N4NSI5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

9305:LOC100929669
gene id: 9305:LOC100929669
uniprot id: A0A7N4PFS4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:LOC100923293
gene id: 9305:LOC100923293
uniprot id: G3WET9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PRNP
gene id: 9305:PRNP
uniprot id: A0A7N4NL04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prion family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane

9305:LOC100916072
gene id: 9305:LOC100916072
uniprot id: A0A7N4P2R4
uniprot id: G3WEH4
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:FAM83C
gene id: 9305:FAM83C
uniprot id: G3X1V8
uniprot id: G3X1W9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAM83 family.
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)-dependent protein kinase C activity. In tissues responsive to insulin, controls fatty acid synthesis and glycolysis by exerting translational control of adipogenic transcription factors such as CEBPB, CEBPD and ATF4 that have G/C rich or uORF in their 5'UTR. Required for ROS-dependent megakaryocyte maturation and platelets formation, controls the expression of mitochondrial respiratory chain genes involved in reactive oxygen species (ROS) synthesis. Involved in miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Modulates cell cycle progression and global translation of pre-B cells, its activation seems to be rate-limiting in tumorigenesis and tumor growth.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit. Interacts with RACK1. Interacts with DICER1, AGO2, TARBP2, MOV10 and RPL7A; they form a large RNA-induced silencing complex (RISC).
messages: Phosphorylation at Ser-210 and Ser-211 promotes nuclear export.
messages: nucleolus

9305:DNAJC2
gene id: 9305:DNAJC2
uniprot id: G3VI89
names: Subcellular Location Annotation
messages: cytosol

9305:HEBP2
gene id: 9305:HEBP2
uniprot id: G3VA21
names: Similarity
messages: Belongs to the HEBP family.

9305:LOC100935408
gene id: 9305:LOC100935408
uniprot id: A0A7N4NWS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100919095
gene id: 9305:LOC100919095
uniprot id: A0A7N4NHS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:HMGB2
gene id: 9305:HMGB2
uniprot id: G3WGP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

9305:ISOC1
gene id: 9305:ISOC1
uniprot id: G3VGN2
names: Similarity
messages: Belongs to the isochorismatase family.

9305:TOP1MT
gene id: 9305:TOP1MT
uniprot id: A0A7N4PGC9
uniprot id: A0A7N4UXW5
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

9305:UPK1A
gene id: 9305:UPK1A
uniprot id: G3VZ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9305:LOC100926077
gene id: 9305:LOC100926077
uniprot id: G3WEL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TIMM10
gene id: 9305:TIMM10
uniprot id: A0A7N4V7Y0
names: Function
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.

9305:LOC100919138
gene id: 9305:LOC100919138
uniprot id: G3VDB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ADIPOR2
gene id: 9305:ADIPOR2
uniprot id: G3WBS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9305:SERPINE2
gene id: 9305:SERPINE2
uniprot id: A0A7N4V656
names: Similarity
messages: Belongs to the serpin family.

9305:DCTPP1
gene id: 9305:DCTPP1
uniprot id: A0A7N4P4E9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homotetramer.
messages: Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
messages: cytosol

9305:ERCC4
gene id: 9305:ERCC4
uniprot id: G3WDR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

9305:MAL
gene id: 9305:MAL
uniprot id: G3WJI8
names: Subcellular Location Annotation
messages: Membrane

9305:RNF170
gene id: 9305:RNF170
uniprot id: A0A7N4NMP2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:GRPEL2
gene id: 9305:GRPEL2
uniprot id: A0A7N4Q0X5
names: Similarity
messages: Belongs to the GrpE family.

9305:FBXO32
gene id: 9305:FBXO32
uniprot id: G3WN58
names: Subcellular Location Annotation
messages: Nucleus

9305:TMEM184C
gene id: 9305:TMEM184C
uniprot id: G3VRW1
names: Subcellular Location Annotation
messages: Membrane

9305:GLOD4
gene id: 9305:GLOD4
uniprot id: G3WE18
names: Similarity
messages: Belongs to the glyoxalase I family.

9305:C1S
gene id: 9305:C1S
uniprot id: G3WVK6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:PKMYT1
gene id: 9305:PKMYT1
uniprot id: A0A7N4PEN0
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:DUOXA1
gene id: 9305:DUOXA1
uniprot id: G3WYU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

9305:CD27
gene id: 9305:CD27
uniprot id: G3WPJ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100930678
gene id: 9305:LOC100930678
uniprot id: G3VFQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:FABP6
gene id: 9305:FABP6
uniprot id: G3W244
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9305:GUF1
gene id: 9305:GUF1
uniprot id: A0A7N4NYT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

9305:NIF3L1
gene id: 9305:NIF3L1
uniprot id: G3WHH7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

9305:SEC16A
gene id: 9305:SEC16A
uniprot id: A0A7N4PYB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

9305:PDXK
gene id: 9305:PDXK
uniprot id: G3X091
names: Similarity
messages: Belongs to the pyridoxine kinase family.

9305:PNPLA7
gene id: 9305:PNPLA7
uniprot id: A0A7N4P624
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:GPR20
gene id: 9305:GPR20
uniprot id: A0A7N4UY53
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:OLFM1
gene id: 9305:OLFM1
uniprot id: A0A7N4UX22
uniprot id: G3WZT5
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

9305:AXIN2
gene id: 9305:AXIN2
uniprot id: G3VT89
names: Subcellular Location Annotation
messages: Cytoplasm

9305:PAQR6
gene id: 9305:PAQR6
uniprot id: A0A7N4P8W3
uniprot id: G3WMC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9305:LOC105749391
gene id: 9305:LOC105749391
uniprot id: A0A7N4NQZ4
names: Subcellular Location Annotation
messages: Membrane

9305:CAMK1D
gene id: 9305:CAMK1D
uniprot id: A0A7N4PL52
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:SHFL
gene id: 9305:SHFL
uniprot id: G3W6B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHFL family.
messages: Nucleus
messages: P-body

9305:EPHA4
gene id: 9305:EPHA4
uniprot id: G3WZW2
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

9305:NUP107
gene id: 9305:NUP107
uniprot id: A0A7N4V6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

9305:LAMP2
gene id: 9305:LAMP2
uniprot id: G3WBL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

9305:SEMA3B
gene id: 9305:SEMA3B
uniprot id: A0A7N4NZ77
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:DOCK10
gene id: 9305:DOCK10
uniprot id: G3X2A3
uniprot id: G3X2A4
names: Similarity
messages: Belongs to the DOCK family.

9305:AASS
gene id: 9305:AASS
uniprot id: G3WY37
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

9305:DMRT2
gene id: 9305:DMRT2
uniprot id: G3W5W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

9305:LOC105750145
gene id: 9305:LOC105750145
uniprot id: A0A7N4UYB0
names: Similarity
messages: Belongs to the CD200R family.

9305:NFIL3
gene id: 9305:NFIL3
uniprot id: A0A7N4UZ81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. Protects pro-B cells from programmed cell death.
messages: Belongs to the bZIP family. NFIL3 subfamily.
messages: Homodimer. Binds DNA as a dimer.
messages: Nucleus

9305:XDH
gene id: 9305:XDH
uniprot id: G3WL03
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Homodimer. Interacts with BTN1A1.
messages: Peroxisome

9305:MID1
gene id: 9305:MID1
uniprot id: G3WM73
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

9305:CD3E
gene id: 9305:CD3E
uniprot id: G3WKI7
names: Subcellular Location Annotation
messages: Membrane

9305:ADCY9
gene id: 9305:ADCY9
uniprot id: G3WH44
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

9305:UBXN1
gene id: 9305:UBXN1
uniprot id: A0A7N4PF03
uniprot id: G3VR25
names: Subcellular Location Annotation
messages: Cytoplasm

9305:CORO1A
gene id: 9305:CORO1A
uniprot id: A0A7N4NYU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat coronin family.
messages: Binds actin.
messages: Membrane
messages: cell cortex
messages: cytoskeleton
messages: phagosome membrane

9305:HEATR1
gene id: 9305:HEATR1
uniprot id: G3W120
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEATR1/UTP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

9305:LOC100920300
gene id: 9305:LOC100920300
uniprot id: G3VD59
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9305:LOC100926596
gene id: 9305:LOC100926596
uniprot id: G3W2I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PREB
gene id: 9305:PREB
uniprot id: A0A7N4P275
uniprot id: G3WGF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER.
messages: Interacts with SAR1B (GDP-bound form). Interacts with MIA2; recruits PREB to endoplasmic reticulum exit sites.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription.

9305:G6PC3
gene id: 9305:G6PC3
uniprot id: G3WQH7
uniprot id: G3WQH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

9305:EFNB2
gene id: 9305:EFNB2
uniprot id: A0A7N4NV76
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:RPL23A
gene id: 9305:RPL23A
uniprot id: A0A7N4PY64
uniprot id: G3WNW4
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

9305:LOC100916020
gene id: 9305:LOC100916020
uniprot id: A0A7N4PJY1
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100934317
gene id: 9305:LOC100934317
uniprot id: G3VWD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide.
messages: Secreted
messages: When bound to LPS, interacts (via C-terminus) with soluble and membrane-bound CD14.

9305:GRIN1
gene id: 9305:GRIN1
uniprot id: A0A7N4UZ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9305:SAHAI-12
gene id: 9305:SAHAI-12
uniprot id: B3F368
names: Similarity
messages: Belongs to the MHC class I family.

9305:CNIH4
gene id: 9305:CNIH4
uniprot id: A0A7N4PXP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

9305:PRDM1
gene id: 9305:PRDM1
uniprot id: G3W8I5
uniprot id: G3W8I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

9305:UNC5C
gene id: 9305:UNC5C
uniprot id: A0A7N4PHN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

9305:NR2E1
gene id: 9305:NR2E1
uniprot id: G3X050
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9305:NR5A2
gene id: 9305:NR5A2
uniprot id: G3WD27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

9305:CDK5RAP3
gene id: 9305:CDK5RAP3
uniprot id: G3VWI2
names: Similarity
messages: Belongs to the CDK5RAP3 family.

9305:SFMBT1
gene id: 9305:SFMBT1
uniprot id: G3VNX7
names: Subcellular Location Annotation
messages: Nucleus

9305:LHX9
gene id: 9305:LHX9
uniprot id: A0A7N4PMP1
uniprot id: A0A7N4V627
uniprot id: G3WGF5
names: Subcellular Location Annotation
messages: Nucleus

9305:ITGA2B
gene id: 9305:ITGA2B
uniprot id: G3WU27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9305:LOC100922237
gene id: 9305:LOC100922237
uniprot id: A0A7N4NK68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:XPC
gene id: 9305:XPC
uniprot id: G3VDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPC family.
messages: Nucleus

9305:LOC100923479
gene id: 9305:LOC100923479
uniprot id: A0A7N4P4J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CSAD
gene id: 9305:CSAD
uniprot id: G3VEQ4
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9305:PARG
gene id: 9305:PARG
uniprot id: G3VT35
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

9305:NBR1
gene id: 9305:NBR1
uniprot id: A0A7N4V1D6
names: Subcellular Location Annotation
messages: autophagosome

9305:LRRC8E
gene id: 9305:LRRC8E
uniprot id: A0A7N4PR96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9305:LOC105751019
gene id: 9305:LOC105751019
uniprot id: G3VRN5
names: Similarity
messages: Belongs to the MS4A family.

9305:APOA1
gene id: 9305:APOA1
uniprot id: A0A7N4NQ23
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

9305:HR
gene id: 9305:HR
uniprot id: A0A7N4V860
uniprot id: G3X0V2
names: Subcellular Location Annotation
messages: Nucleus

9305:RAB32
gene id: 9305:RAB32
uniprot id: G3W0Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

9305:WNT9A
gene id: 9305:WNT9A
uniprot id: G3WH52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9305:BFSP1
gene id: 9305:BFSP1
uniprot id: G3W818
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cell cortex
messages: cytoskeleton

9305:CMKLR1
gene id: 9305:CMKLR1
uniprot id: A0A7N4PC33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

9305:ATP4B
gene id: 9305:ATP4B
uniprot id: G3WQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

9305:PGAP2
gene id: 9305:PGAP2
uniprot id: A0A7N4PX01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PGAP2 family.
messages: Interacts with PGAP2IP.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

9305:MRPL51
gene id: 9305:MRPL51
uniprot id: A0A7N4PHY1
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.

9305:KCNK5
gene id: 9305:KCNK5
uniprot id: A0A7N4V038
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9305:CCNK
gene id: 9305:CCNK
uniprot id: G3VQZ0
names: Similarity
messages: Belongs to the cyclin family.

9305:MC3R
gene id: 9305:MC3R
uniprot id: A0A7N4P8A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane

9305:RAB38
gene id: 9305:RAB38
uniprot id: G3VG12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

9305:MLLT11
gene id: 9305:MLLT11
uniprot id: A0A7N4NHM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

9305:GCG
gene id: 9305:GCG
uniprot id: G3WZV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

9305:NPR1
gene id: 9305:NPR1
uniprot id: G3W938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

9305:KCNJ10
gene id: 9305:KCNJ10
uniprot id: A0A7N4PFL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9305:USE1
gene id: 9305:USE1
uniprot id: A0A7N4PD91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:TBC1D24
gene id: 9305:TBC1D24
uniprot id: G3WNG7
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse
messages: Synapse

9305:MYOG
gene id: 9305:MYOG
uniprot id: G3WUV0
names: Subcellular Location Annotation
messages: Nucleus

9305:EXTL1
gene id: 9305:EXTL1
uniprot id: G3W0D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

9305:ATP8B1
gene id: 9305:ATP8B1
uniprot id: G3WZN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9305:CD14
gene id: 9305:CD14
uniprot id: G3WV43
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: Membrane raft
messages: Secreted

9305:TMED9
gene id: 9305:TMED9
uniprot id: G3WQS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:PARP3
gene id: 9305:PARP3
uniprot id: G3VZK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

9305:PPP1R10
gene id: 9305:PPP1R10
uniprot id: A0A7N4PBM5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers.

9305:NDUFA1
gene id: 9305:NDUFA1
uniprot id: A0A7N4PJ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

9305:SCRN2
gene id: 9305:SCRN2
uniprot id: G3VMJ1
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

9305:TMEFF2
gene id: 9305:TMEFF2
uniprot id: A0A7N4NM75
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:EXOC3
gene id: 9305:EXOC3
uniprot id: G3X2Z6
names: Similarity
messages: Belongs to the SEC6 family.

9305:LIMS2
gene id: 9305:LIMS2
uniprot id: G3VV48
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.
messages: Cell membrane
messages: Part of the heterotrimeric IPP complex composed of integrin-linked kinase (ILK), LIMS1 or LIMS2, and PARVA.
messages: focal adhesion

9305:ZC3H12A
gene id: 9305:ZC3H12A
uniprot id: A0A7N4UXW6
names: Similarity
messages: Belongs to the ZC3H12 family.

9305:PPIE
gene id: 9305:PPIE
uniprot id: A0A7N4V6D6
uniprot id: G3X115
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.

9305:PARP6
gene id: 9305:PARP6
uniprot id: G3W7W9
names: Similarity
messages: Belongs to the ARTD/PARP family.

9305:EFHC1
gene id: 9305:EFHC1
uniprot id: G3WKQ8
names: Subcellular Location Annotation
messages: cilium axoneme

9305:GSX1
gene id: 9305:GSX1
uniprot id: A0A7N4NL71
names: Subcellular Location Annotation
messages: Nucleus

9305:PPDPF
gene id: 9305:PPDPF
uniprot id: G3X1U9
names: Similarity
messages: Belongs to the PPDPF family.

9305:LOC100927686
gene id: 9305:LOC100927686
uniprot id: G3VV47
names: Subcellular Location Annotation
messages: Membrane

9305:DPM3
gene id: 9305:DPM3
uniprot id: A0A7N4P357
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

9305:LOC100915444
gene id: 9305:LOC100915444
uniprot id: G3WF68
names: Subcellular Location Annotation
messages: Membrane

9305:RNF112
gene id: 9305:RNF112
uniprot id: G3WLF8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9305:ADAMTS5
gene id: 9305:ADAMTS5
uniprot id: G3WI56
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9305:SPSB4
gene id: 9305:SPSB4
uniprot id: G3X144
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

9305:TSN
gene id: 9305:TSN
uniprot id: G3WE39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

9305:SIGIRR
gene id: 9305:SIGIRR
uniprot id: A0A7N4UZ39
uniprot id: G3VYY0
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9305:DARS2
gene id: 9305:DARS2
uniprot id: A0A7N4PNB3
uniprot id: G3VVB2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

9305:KRT4
gene id: 9305:KRT4
uniprot id: G3VTL1
names: Similarity
messages: Belongs to the intermediate filament family.

9305:RAB18
gene id: 9305:RAB18
uniprot id: A0A7N4PM01
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

9305:RPS24
gene id: 9305:RPS24
uniprot id: A0A7N4V7D2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

9305:RACK1
gene id: 9305:RACK1
uniprot id: G3WI55
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

9305:SLC6A17
gene id: 9305:SLC6A17
uniprot id: G3W453
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9305:LOC100934611
gene id: 9305:LOC100934611
uniprot id: G3VL91
names: Similarity
messages: Belongs to the CD200R family.

9305:SPTB
gene id: 9305:SPTB
uniprot id: A0A7N4P7T0
names: Similarity
messages: Belongs to the spectrin family.

9305:B3GAT3
gene id: 9305:B3GAT3
uniprot id: G3VNI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:GPATCH1
gene id: 9305:GPATCH1
uniprot id: G3WTW2
names: Similarity
messages: Belongs to the GPATCH1 family.

9305:KRT17
gene id: 9305:KRT17
uniprot id: G3VXT1
names: Similarity
messages: Belongs to the intermediate filament family.

9305:LAMP5
gene id: 9305:LAMP5
uniprot id: G3WH95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

9305:MYO1G
gene id: 9305:MYO1G
uniprot id: G3VGW6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9305:LOC100932549
gene id: 9305:LOC100932549
uniprot id: G3WPN0
names: Similarity
messages: Belongs to the intermediate filament family.

9305:MBD4
gene id: 9305:MBD4
uniprot id: G3WID2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with MLH1.
messages: Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
messages: Nucleus

9305:CLN8
gene id: 9305:CLN8
uniprot id: G3WZ61
names: Subcellular Location Annotation
messages: Membrane

9305:BBS4
gene id: 9305:BBS4
uniprot id: G3WV05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

9305:ACTN2
gene id: 9305:ACTN2
uniprot id: A0A7N4P4Q3
uniprot id: G3VUD5
names: Similarity
messages: Belongs to the alpha-actinin family.

9305:SLC39A1
gene id: 9305:SLC39A1
uniprot id: G3WE50
names: Subcellular Location Annotation
messages: Membrane

9305:PPP1R16B
gene id: 9305:PPP1R16B
uniprot id: A0A7N4NIR5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:TAC1
gene id: 9305:TAC1
uniprot id: G3W054
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

9305:SIM1
gene id: 9305:SIM1
uniprot id: G3WUK1
names: Subcellular Location Annotation
messages: Nucleus

9305:EPGN
gene id: 9305:EPGN
uniprot id: G3WW74
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100934526
gene id: 9305:LOC100934526
uniprot id: G3VXJ6
uniprot id: G3W3K3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.

9305:PLA2G4F
gene id: 9305:PLA2G4F
uniprot id: G3VNT3
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9305:LOC100931131
gene id: 9305:LOC100931131
uniprot id: A0A7N4NGQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

9305:AQP11
gene id: 9305:AQP11
uniprot id: A0A7N4PCL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

9305:XYLB
gene id: 9305:XYLB
uniprot id: G3WAV7
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

9305:SAHAI-01
gene id: 9305:SAHAI-01
uniprot id: B3F356
names: Similarity
messages: Belongs to the MHC class I family.

9305:RAP2C
gene id: 9305:RAP2C
uniprot id: A0A7N4V7D5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

9305:LOC100934370
gene id: 9305:LOC100934370
uniprot id: A0A7N4NRP6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:RBM48
gene id: 9305:RBM48
uniprot id: A0A7N4PGC8
uniprot id: G3X3W1
names: Similarity
messages: Belongs to the RBM48 family.

9305:MAP1LC3A
gene id: 9305:MAP1LC3A
uniprot id: A0A7N4PFL1
names: Similarity
messages: Belongs to the ATG8 family.

9305:ADPRH
gene id: 9305:ADPRH
uniprot id: G3VH32
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

9305:WDFY2
gene id: 9305:WDFY2
uniprot id: A0A7N4UYD6
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9305:MDGA1
gene id: 9305:MDGA1
uniprot id: G3WWI0
uniprot id: G3WWI1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:GAL3ST2
gene id: 9305:GAL3ST2
uniprot id: A0A7N4NN91
uniprot id: G3WTL1
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

9305:LTN1
gene id: 9305:LTN1
uniprot id: A0A7N4P540
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

9305:EFNA1
gene id: 9305:EFNA1
uniprot id: G3VY37
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:PRPF4
gene id: 9305:PRPF4
uniprot id: G3WZG5
names: Subcellular Location Annotation
messages: Nucleus speckle

9305:C1H5orf22
gene id: 9305:C1H5orf22
uniprot id: A0A7N4NMU4
uniprot id: G3WSA8
names: Similarity
messages: Belongs to the UPF0489 family.

9305:NSMCE1
gene id: 9305:NSMCE1
uniprot id: A0A7N4PKL3
uniprot id: A0A7N4V878
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus
messages: RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Involved in maintenance of genome integrity, DNA damage response and DNA repair.
messages: telomere

9305:MTAP
gene id: 9305:MTAP
uniprot id: G3VJ26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

9305:NNT
gene id: 9305:NNT
uniprot id: G3W0Q2
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

9305:LOC100919364
gene id: 9305:LOC100919364
uniprot id: G3VF43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:EIF2D
gene id: 9305:EIF2D
uniprot id: A0A7N4PB58
names: Similarity
messages: Belongs to the eIF2D family.

9305:PPM1K
gene id: 9305:PPM1K
uniprot id: A0A7N4PZP7
names: Similarity
messages: Belongs to the PP2C family.

9305:NDUFAF4
gene id: 9305:NDUFAF4
uniprot id: A0A7N4NGM1
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

9305:LOC100916021
gene id: 9305:LOC100916021
uniprot id: A0A7N4NPV7
names: Similarity
messages: Belongs to the TGF-beta family.

9305:ACTL9
gene id: 9305:ACTL9
uniprot id: A0A7N4NX06
names: Similarity
messages: Belongs to the actin family.

9305:ABRAXAS2
gene id: 9305:ABRAXAS2
uniprot id: G3VFI9
names: Subcellular Location Annotation
messages: Nucleus

9305:ATP6V1E1
gene id: 9305:ATP6V1E1
uniprot id: A0A7N4V0U4
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

9305:SCPEP1
gene id: 9305:SCPEP1
uniprot id: A0A7N4P6I3
uniprot id: G3VPW3
names: Similarity
messages: Belongs to the peptidase S10 family.

9305:ENTPD2
gene id: 9305:ENTPD2
uniprot id: G3W8C0
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9305:LOC100934825
gene id: 9305:LOC100934825
uniprot id: A0A7N4PPS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with BRAWNIN.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

9305:NTS
gene id: 9305:NTS
uniprot id: A0A7N4PVE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

9305:NXPH3
gene id: 9305:NXPH3
uniprot id: G3W0B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

9305:LOC100927121
gene id: 9305:LOC100927121
uniprot id: G3VUU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100926475
gene id: 9305:LOC100926475
uniprot id: A0A7N4PU01
names: Subcellular Location Annotation
messages: Membrane

9305:ZNF277
gene id: 9305:ZNF277
uniprot id: G3WJD3
names: Similarity
messages: Belongs to the ZNF277 family.

9305:LPAR1
gene id: 9305:LPAR1
uniprot id: G3VT67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

9305:PAQR3
gene id: 9305:PAQR3
uniprot id: G3VX60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9305:HAAO
gene id: 9305:HAAO
uniprot id: G3W5N0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

9305:MMP13
gene id: 9305:MMP13
uniprot id: G3WPX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CCN2. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
messages: Secreted

9305:LIM2
gene id: 9305:LIM2
uniprot id: A0A7N4P368
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis.

9305:ECHDC1
gene id: 9305:ECHDC1
uniprot id: G3X2Z7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

9305:PRPH
gene id: 9305:PRPH
uniprot id: G3VSD9
names: Similarity
messages: Belongs to the intermediate filament family.

9305:KCNE2
gene id: 9305:KCNE2
uniprot id: G3VF67
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9305:STT3A
gene id: 9305:STT3A
uniprot id: G3WYH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

9305:PMP22
gene id: 9305:PMP22
uniprot id: A0A7N4NP69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

9305:RAB3D
gene id: 9305:RAB3D
uniprot id: A0A7N4NRJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

9305:TCF7L2
gene id: 9305:TCF7L2
uniprot id: A0A7N4NG60
uniprot id: A0A7N4P2P3
uniprot id: A0A7N4P9A7
uniprot id: G3WYE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

9305:ALDH1A3
gene id: 9305:ALDH1A3
uniprot id: G3W6D5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9305:CRH
gene id: 9305:CRH
uniprot id: A0A7N4P8Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

9305:NBN
gene id: 9305:NBN
uniprot id: G3VFB2
uniprot id: G3VFB3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
messages: Component of the MRN complex.
messages: Nucleus
messages: telomere

9305:LOC100920675
gene id: 9305:LOC100920675
uniprot id: G3W7H3
names: Subcellular Location Annotation
messages: Membrane

9305:HIF1A
gene id: 9305:HIF1A
uniprot id: G3WFI3
names: Subcellular Location Annotation
messages: Cytoplasm

9305:LOC100919431
gene id: 9305:LOC100919431
uniprot id: G3WT88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:ATAT1
gene id: 9305:ATAT1
uniprot id: G3VXS2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation strongly increases tubulin acetylation.
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Component of the BBSome complex. Interacts with AP2 alpha-adaptins, including AP2A2, but not with AP1 gamma-adaptin (AP1G1/AP1G2); this interaction is required for efficient alpha-tubulin acetylation, hence clathrin-coated pits are sites of microtubule acetylation.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

9305:CHMP4C
gene id: 9305:CHMP4C
uniprot id: G3WAS6
names: Similarity
messages: Belongs to the SNF7 family.

9305:LOC100925292
gene id: 9305:LOC100925292
uniprot id: A0A7N4P0G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100922314
gene id: 9305:LOC100922314
uniprot id: A0A7N4PVS5
names: Similarity
messages: Belongs to the intermediate filament family.

9305:RP2
gene id: 9305:RP2
uniprot id: A0A7N4PWI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

9305:PFAS
gene id: 9305:PFAS
uniprot id: G3WG54
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

9305:C6H4orf47
gene id: 9305:C6H4orf47
uniprot id: G3WHR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0602 family.
messages: centrosome

9305:ARF5
gene id: 9305:ARF5
uniprot id: G3WQM0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

9305:ACTR6
gene id: 9305:ACTR6
uniprot id: G3WAN7
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.

9305:RFFL
gene id: 9305:RFFL
uniprot id: A0A7N4NRT6
uniprot id: A0A7N4PU08
names: Subcellular Location Annotation
messages: Cell membrane

9305:LOC100931042
gene id: 9305:LOC100931042
uniprot id: G3W4X4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9305:SRSF5
gene id: 9305:SRSF5
uniprot id: G3VJA0
names: Similarity
messages: Belongs to the splicing factor SR family.

9305:LOC100914080
gene id: 9305:LOC100914080
uniprot id: G3VIE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TMPRSS2
gene id: 9305:TMPRSS2
uniprot id: G3VR62
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:PFKP
gene id: 9305:PFKP
uniprot id: A0A7N4NQ17
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:NEMP1
gene id: 9305:NEMP1
uniprot id: G3VTU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

9305:SELENBP1
gene id: 9305:SELENBP1
uniprot id: G3WNJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Interacts with USP33.
messages: Membrane
messages: Nucleus
messages: cytosol

9305:NEU2
gene id: 9305:NEU2
uniprot id: G3VZV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

9305:LOC100914034
gene id: 9305:LOC100914034
uniprot id: A0A7N4NT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:SEMA3C
gene id: 9305:SEMA3C
uniprot id: G3VSX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:TMEM88
gene id: 9305:TMEM88
uniprot id: A0A7N4PZW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

9305:FAM216A
gene id: 9305:FAM216A
uniprot id: G3WP71
names: Similarity
messages: Belongs to the FAM216 family.

9305:DDAH2
gene id: 9305:DDAH2
uniprot id: G3VW52
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

9305:FLCN
gene id: 9305:FLCN
uniprot id: A0A7N4P0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

9305:TMEM186
gene id: 9305:TMEM186
uniprot id: A0A7N4PBK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM186 family.
messages: Membrane

9305:HOXB2
gene id: 9305:HOXB2
uniprot id: G3WFW2
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100933475
gene id: 9305:LOC100933475
uniprot id: G3WJB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:YWHAZ
gene id: 9305:YWHAZ
uniprot id: A0A7N4P7P6
uniprot id: G3WHE0
names: Similarity
messages: Belongs to the 14-3-3 family.

9305:CLDN19
gene id: 9305:CLDN19
uniprot id: A0A7N4V1L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9305:CENPQ
gene id: 9305:CENPQ
uniprot id: G3VKL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

9305:ABHD1
gene id: 9305:ABHD1
uniprot id: G3WG86
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

9305:LOC100924617
gene id: 9305:LOC100924617
uniprot id: G3VPW6
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9305:LOC100928152
gene id: 9305:LOC100928152
uniprot id: A0A7N4PKZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100927632
gene id: 9305:LOC100927632
uniprot id: G3X2C6
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:PTHLH
gene id: 9305:PTHLH
uniprot id: A0A7N4PWS6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the parathyroid hormone family.
messages: Cytoplasm
messages: Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Up-regulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath.
messages: Nucleus
messages: Osteostatin is a potent inhibitor of osteoclastic bone resorption.
messages: PTHrP interacts with PTH1R (via N-terminal extracellular domain).
messages: Secreted
messages: There are several secretory forms, including osteostatin, arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its own receptors that mediates the normal paracrine, autocrine and endocrine actions.

9305:ETFDH
gene id: 9305:ETFDH
uniprot id: A0A7N4PYP6
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

9305:ALDH1A2
gene id: 9305:ALDH1A2
uniprot id: G3WFU4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9305:DUSP16
gene id: 9305:DUSP16
uniprot id: G3WI08
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9305:DUSP10
gene id: 9305:DUSP10
uniprot id: A0A7N4NZ96
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9305:CEP162
gene id: 9305:CEP162
uniprot id: G3VCM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP162 family.
messages: centriole

9305:LOC100924906
gene id: 9305:LOC100924906
uniprot id: G3WXL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TPRA1
gene id: 9305:TPRA1
uniprot id: G3WBT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

9305:MFSD10
gene id: 9305:MFSD10
uniprot id: A0A7N4PUS7
uniprot id: G3WD42
names: Subcellular Location Annotation
messages: Membrane

9305:CSNK2B
gene id: 9305:CSNK2B
uniprot id: A0A7N4NV50
uniprot id: G3VEQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

9305:TMEM107
gene id: 9305:TMEM107
uniprot id: A0A7N4NU76
names: Subcellular Location Annotation
messages: Membrane

9305:ABCB11
gene id: 9305:ABCB11
uniprot id: G3WW89
names: Subcellular Location Annotation
messages: Endosome

9305:HMGCS1
gene id: 9305:HMGCS1
uniprot id: A0A7N4PZ86
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

9305:CDH10
gene id: 9305:CDH10
uniprot id: G3W0K6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9305:PROC
gene id: 9305:PROC
uniprot id: A0A7N4P981
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:FLAD1
gene id: 9305:FLAD1
uniprot id: A0A7N4NGG8
names: Function
names: Similarity
messages: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
messages: In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

9305:NOP56
gene id: 9305:NOP56
uniprot id: G3WXS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

9305:PSMC1
gene id: 9305:PSMC1
uniprot id: G3WWW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

9305:FFAR1
gene id: 9305:FFAR1
uniprot id: G3VX52
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:PIGV
gene id: 9305:PIGV
uniprot id: G3WLI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

9305:LPIN2
gene id: 9305:LPIN2
uniprot id: A0A7N4PZE5
uniprot id: G3VZS7
names: Similarity
messages: Belongs to the lipin family.

9305:ACTG2
gene id: 9305:ACTG2
uniprot id: G3VP69
names: Similarity
messages: Belongs to the actin family.

9305:EXTL2
gene id: 9305:EXTL2
uniprot id: A0A7N4V220
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9305:ST6GAL2
gene id: 9305:ST6GAL2
uniprot id: A0A7N4Q2B3
uniprot id: G3WKN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9305:MSTO1
gene id: 9305:MSTO1
uniprot id: A0A7N4PI03
uniprot id: G3WE78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the misato family.
messages: Mitochondrion outer membrane

9305:CHMP2A
gene id: 9305:CHMP2A
uniprot id: G3VR36
names: Similarity
messages: Belongs to the SNF7 family.

9305:MINDY3
gene id: 9305:MINDY3
uniprot id: G3WFZ5
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

9305:RPS12
gene id: 9305:RPS12
uniprot id: A0A7N4Q1B2
uniprot id: G3W4F8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

9305:SLA
gene id: 9305:SLA
uniprot id: A0A7N4PAV3
uniprot id: A0A7N4PWC4
names: Subcellular Location Annotation
messages: Cytoplasm

9305:PDGFC
gene id: 9305:PDGFC
uniprot id: A0A7N4NT29
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:IMP4
gene id: 9305:IMP4
uniprot id: A0A7N4PMJ4
uniprot id: G3W2A1
names: Subcellular Location Annotation
messages: nucleolus

9305:LOC100917667
gene id: 9305:LOC100917667
uniprot id: G3W2X9
names: Subcellular Location Annotation
messages: Membrane

9305:FH
gene id: 9305:FH
uniprot id: G3WGT2
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

9305:BCLAF1
gene id: 9305:BCLAF1
uniprot id: A0A7N4P0T8
uniprot id: A0A7N4P3U0
uniprot id: A0A7N4PCQ1
uniprot id: A0A7N4PUP6
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

9305:TFAP2B
gene id: 9305:TFAP2B
uniprot id: A0A7N4PRY9
names: Similarity
messages: Belongs to the AP-2 family.

9305:RAB3GAP1
gene id: 9305:RAB3GAP1
uniprot id: A0A7N4V3A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm

9305:TRIM36
gene id: 9305:TRIM36
uniprot id: A0A7N4NZ41
uniprot id: G3W4K2
names: Subcellular Location Annotation
messages: cytoskeleton

9305:NDUFB3
gene id: 9305:NDUFB3
uniprot id: G3WKB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

9305:ME2
gene id: 9305:ME2
uniprot id: G3WM32
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

9305:ABAT
gene id: 9305:ABAT
uniprot id: G3WIN3
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer; disulfide-linked.

9305:LOC100927715
gene id: 9305:LOC100927715
uniprot id: A0A7N4NKZ5
names: Function
names: Similarity
messages: Belongs to the MS4A family.
messages: May be involved in signal transduction as a component of a multimeric receptor complex.

9305:NPTX2
gene id: 9305:NPTX2
uniprot id: G3WXE7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100917788
gene id: 9305:LOC100917788
uniprot id: A0A7N4NP49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ADRB2
gene id: 9305:ADRB2
uniprot id: G3WFD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
messages: Cell membrane
messages: Early endosome
messages: Golgi apparatus
messages: Membrane

9305:ANAPC13
gene id: 9305:ANAPC13
uniprot id: G3VX80
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

9305:RNF43
gene id: 9305:RNF43
uniprot id: A0A7N4V6E3
uniprot id: G3WAH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Belongs to the ZNRF3 family.
messages: Cell membrane
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

9305:LOC100922760
gene id: 9305:LOC100922760
uniprot id: A0A7N4PLK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100921555
gene id: 9305:LOC100921555
uniprot id: G3W5I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

9305:RPL9
gene id: 9305:RPL9
uniprot id: G3VR23
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

9305:LOC100929546
gene id: 9305:LOC100929546
uniprot id: A0A7N4NLI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:NUDT12
gene id: 9305:NUDT12
uniprot id: G3VKB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

9305:PLIN1
gene id: 9305:PLIN1
uniprot id: G3WLK6
names: Similarity
messages: Belongs to the perilipin family.

9305:TM6SF2
gene id: 9305:TM6SF2
uniprot id: G3WFS1
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100926676
gene id: 9305:LOC100926676
uniprot id: G3WEF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Membrane

9305:NPTX1
gene id: 9305:NPTX1
uniprot id: G3VXC2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100931086
gene id: 9305:LOC100931086
uniprot id: A0A7N4PI98
names: Subcellular Location Annotation
messages: Membrane

9305:PCK2
gene id: 9305:PCK2
uniprot id: A0A7N4PRF7
uniprot id: G3WW12
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

9305:PIP4P2
gene id: 9305:PIP4P2
uniprot id: G3WHM7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

9305:DPYD
gene id: 9305:DPYD
uniprot id: G3WX52
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

9305:NTHL1
gene id: 9305:NTHL1
uniprot id: G3WTH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.
messages: Interacts with YBX1.
messages: Mitochondrion
messages: Nucleus

9305:DBNDD2
gene id: 9305:DBNDD2
uniprot id: A0A7N4PYR9
names: Similarity
messages: Belongs to the dysbindin family.

9305:B4GALT6
gene id: 9305:B4GALT6
uniprot id: A0A7N4P0A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9305:LOC100913905
gene id: 9305:LOC100913905
uniprot id: G3VNT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:AMOTL1
gene id: 9305:AMOTL1
uniprot id: A0A7N4NUL1
names: Similarity
messages: Belongs to the angiomotin family.

9305:CLCN3
gene id: 9305:CLCN3
uniprot id: A0A7N4PVS6
uniprot id: G3WDR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

9305:ATP5ME
gene id: 9305:ATP5ME
uniprot id: A0A7N4NZF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

9305:ESD
gene id: 9305:ESD
uniprot id: A0A7N4NP77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasmic vesicle
messages: Serine hydrolase involved in the detoxification of formaldehyde.

9305:TECPR1
gene id: 9305:TECPR1
uniprot id: G3WSL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TECPR1 family.
messages: Lysosome membrane
messages: autophagosome membrane

9305:RBBP5
gene id: 9305:RBBP5
uniprot id: A0A7N4Q0W4
uniprot id: G3WID9
names: Subcellular Location Annotation
messages: Nucleus

9305:PIGS
gene id: 9305:PIGS
uniprot id: G3WLL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:NKX6-3
gene id: 9305:NKX6-3
uniprot id: A0A7N4NMC0
names: Subcellular Location Annotation
messages: Nucleus

9305:IL1RL2
gene id: 9305:IL1RL2
uniprot id: A0A7N4PRK2
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9305:CYSLTR1
gene id: 9305:CYSLTR1
uniprot id: G3WL60
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:LOC100920614
gene id: 9305:LOC100920614
uniprot id: G3VX68
names: Similarity
messages: Belongs to the cytochrome b5 family.

9305:LOC100928175
gene id: 9305:LOC100928175
uniprot id: A0A7N4V1I5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

9305:CDC42EP3
gene id: 9305:CDC42EP3
uniprot id: A0A7N4P2R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

9305:HADH
gene id: 9305:HADH
uniprot id: A0A7N4NWL5
uniprot id: G3VRA3
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

9305:LOC100926310
gene id: 9305:LOC100926310
uniprot id: A0A7N4PQA8
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

9305:LOC100932654
gene id: 9305:LOC100932654
uniprot id: A0A7N4PVM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:AP1S3
gene id: 9305:AP1S3
uniprot id: G3WBM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

9305:DPYSL3
gene id: 9305:DPYSL3
uniprot id: G3WM45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Cytoplasm
messages: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
messages: growth cone

9305:IFI30
gene id: 9305:IFI30
uniprot id: A0A7N4PUE7
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

9305:LIPH
gene id: 9305:LIPH
uniprot id: G3WHF6
uniprot id: G3WHF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Membrane
messages: Secreted

9305:PRMT5
gene id: 9305:PRMT5
uniprot id: G3WII7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Nucleus

9305:YIPF6
gene id: 9305:YIPF6
uniprot id: A0A7N4UZS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

9305:LOC100934287
gene id: 9305:LOC100934287
uniprot id: A0A7N4NH95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TNFRSF11B
gene id: 9305:TNFRSF11B
uniprot id: G3WTJ0
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:PAQR7
gene id: 9305:PAQR7
uniprot id: G3VTW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9305:SLCO1C1
gene id: 9305:SLCO1C1
uniprot id: G3WWQ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:LNPK
gene id: 9305:LNPK
uniprot id: A0A7N4P3K5
uniprot id: A0A7N4PHJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

9305:EPCAM
gene id: 9305:EPCAM
uniprot id: A0A7N4P304
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:LOC100923011
gene id: 9305:LOC100923011
uniprot id: A0A7N4V756
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PLOD3
gene id: 9305:PLOD3
uniprot id: G3VFK0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9305:URAD
gene id: 9305:URAD
uniprot id: A0A7N4NNF6
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

9305:LOC100935365
gene id: 9305:LOC100935365
uniprot id: A0A7N4PHJ0
names: Similarity
messages: Belongs to the argonaute family.

9305:GGT7
gene id: 9305:GGT7
uniprot id: G3X092
names: Similarity
messages: Belongs to the gamma-glutamyltransferase family.

9305:LOC100931609
gene id: 9305:LOC100931609
uniprot id: A0A7N4NKN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MTMR6
gene id: 9305:MTMR6
uniprot id: G3WJM5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9305:DTNB
gene id: 9305:DTNB
uniprot id: G3W6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

9305:PFKL
gene id: 9305:PFKL
uniprot id: G3VRD2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100920666
gene id: 9305:LOC100920666
uniprot id: A0A7N4PJG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:FZD7
gene id: 9305:FZD7
uniprot id: G3WII5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:GPR55
gene id: 9305:GPR55
uniprot id: G3VGI0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:CUL4B
gene id: 9305:CUL4B
uniprot id: G3WD56
uniprot id: G3WD57
names: Similarity
messages: Belongs to the cullin family.

9305:LOC100932482
gene id: 9305:LOC100932482
uniprot id: G3WKX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9305:TSSK6
gene id: 9305:TSSK6
uniprot id: G3VE92
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:LOC100917582
gene id: 9305:LOC100917582
uniprot id: G3W033
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:HSD17B7
gene id: 9305:HSD17B7
uniprot id: G3WM61
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

9305:CYFIP1
gene id: 9305:CYFIP1
uniprot id: G3VTY7
names: Similarity
messages: Belongs to the CYFIP family.

9305:LOC100913500
gene id: 9305:LOC100913500
uniprot id: A0A7N4PEC0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

9305:CA3
gene id: 9305:CA3
uniprot id: A0A7N4PFF5
uniprot id: G3W652
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cytoplasm
messages: Reversible hydration of carbon dioxide.

9305:RPF2
gene id: 9305:RPF2
uniprot id: G3VH44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

9305:PRDM12
gene id: 9305:PRDM12
uniprot id: A0A7N4P226
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

9305:COG4
gene id: 9305:COG4
uniprot id: G3VEL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

9305:GJA5
gene id: 9305:GJA5
uniprot id: A0A7N4Q0N2
uniprot id: G3X1A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9305:LOC100914101
gene id: 9305:LOC100914101
uniprot id: G3WBC3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

9305:ACVR2B
gene id: 9305:ACVR2B
uniprot id: A0A7N4PXP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9305:LOC100920345
gene id: 9305:LOC100920345
uniprot id: A0A7N4PY12
names: Similarity
messages: Belongs to the lst-2 family.

9305:LEO1
gene id: 9305:LEO1
uniprot id: G3WWT3
names: Similarity
messages: Belongs to the LEO1 family.

9305:LOC100919466
gene id: 9305:LOC100919466
uniprot id: A0A7N4V6L1
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

9305:RUNX1T1
gene id: 9305:RUNX1T1
uniprot id: A0A7N4NUX1
names: Similarity
messages: Belongs to the CBFA2T family.

9305:LOC100932664
gene id: 9305:LOC100932664
uniprot id: A0A7N4P1Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

9305:ELP6
gene id: 9305:ELP6
uniprot id: G3VV31
names: Similarity
messages: Belongs to the ELP6 family.

9305:LOC100921632
gene id: 9305:LOC100921632
uniprot id: G3WP05
names: Similarity
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Homodimer.

9305:MON1A
gene id: 9305:MON1A
uniprot id: G3X100
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

9305:ATP6AP1
gene id: 9305:ATP6AP1
uniprot id: A0A7N4P854
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

9305:GMFB
gene id: 9305:GMFB
uniprot id: A0A7N4PXR2
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

9305:TMEM251
gene id: 9305:TMEM251
uniprot id: A0A7N4V577
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM251 family.
messages: Membrane

9305:LCK
gene id: 9305:LCK
uniprot id: A0A7N4PWR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

9305:ARG2
gene id: 9305:ARG2
uniprot id: A0A7N4NYQ3
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

9305:CELF3
gene id: 9305:CELF3
uniprot id: G3WSZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

9305:SIX1
gene id: 9305:SIX1
uniprot id: G3WSV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Cytoplasm
messages: Nucleus

9305:LOC100926484
gene id: 9305:LOC100926484
uniprot id: A0A7N4V394
names: Similarity
messages: Belongs to the multicopper oxidase family.

9305:SGK1
gene id: 9305:SGK1
uniprot id: A0A7N4P7R2
uniprot id: G3W1X6
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:LOC100923620
gene id: 9305:LOC100923620
uniprot id: G3VCB5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

9305:CCNC
gene id: 9305:CCNC
uniprot id: G3WIU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
messages: Nucleus

9305:THBS1
gene id: 9305:THBS1
uniprot id: G3VTZ6
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:SLC10A3
gene id: 9305:SLC10A3
uniprot id: A0A7N4NV32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

9305:RRM2
gene id: 9305:RRM2
uniprot id: G3VT20
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

9305:DBX1
gene id: 9305:DBX1
uniprot id: G3WEB2
names: Subcellular Location Annotation
messages: Nucleus

9305:FSCN2
gene id: 9305:FSCN2
uniprot id: G3WLZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

9305:POC5
gene id: 9305:POC5
uniprot id: G3W3R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

9305:EGR1
gene id: 9305:EGR1
uniprot id: A0A7N4NSC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

9305:PCOLCE
gene id: 9305:PCOLCE
uniprot id: G3W598
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:LOC100926134
gene id: 9305:LOC100926134
uniprot id: G3VSJ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9305:TNFRSF1B
gene id: 9305:TNFRSF1B
uniprot id: G3W5A4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:PSPH
gene id: 9305:PSPH
uniprot id: G3W5X4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

9305:IARS2
gene id: 9305:IARS2
uniprot id: G3VQJ8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9305:PLXNA2
gene id: 9305:PLXNA2
uniprot id: G3VZ33
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:LRRC8B
gene id: 9305:LRRC8B
uniprot id: A0A7N4PXL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9305:MRPL30
gene id: 9305:MRPL30
uniprot id: A0A7N4P4T2
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

9305:DXO
gene id: 9305:DXO
uniprot id: G3W4Y1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

9305:CNPY1
gene id: 9305:CNPY1
uniprot id: G3WN37
names: Similarity
messages: Belongs to the canopy family.

9305:CPLX3
gene id: 9305:CPLX3
uniprot id: A0A7N4UXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

9305:MMGT1
gene id: 9305:MMGT1
uniprot id: A0A7N4PNU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

9305:RARB
gene id: 9305:RARB
uniprot id: G3W7J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9305:ALOXE3
gene id: 9305:ALOXE3
uniprot id: G3WKD6
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:QRSL1
gene id: 9305:QRSL1
uniprot id: G3WKL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

9305:GDNF
gene id: 9305:GDNF
uniprot id: G3WXP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

9305:C3H11orf87
gene id: 9305:C3H11orf87
uniprot id: A0A7N4NZN1
names: Subcellular Location Annotation
messages: Membrane

9305:PTGER4
gene id: 9305:PTGER4
uniprot id: A0A7N4V7E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

9305:VDAC1
gene id: 9305:VDAC1
uniprot id: G3WYY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

9305:ZFYVE27
gene id: 9305:ZFYVE27
uniprot id: A0A7N4NWX1
uniprot id: G3X0G3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: growth cone membrane

9305:DHX8
gene id: 9305:DHX8
uniprot id: A0A7N4PDK8
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100929438
gene id: 9305:LOC100929438
uniprot id: G3W3C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100919671
gene id: 9305:LOC100919671
uniprot id: G3VSB9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

9305:LOC100920297
gene id: 9305:LOC100920297
uniprot id: A0A7N4PJT5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9305:DBX2
gene id: 9305:DBX2
uniprot id: G3WHC4
names: Subcellular Location Annotation
messages: Nucleus

9305:TMED1
gene id: 9305:TMED1
uniprot id: A0A7N4P095
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

9305:LOC100929157
gene id: 9305:LOC100929157
uniprot id: A0A7N4V2Q4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:FEZ2
gene id: 9305:FEZ2
uniprot id: A0A7N4PX00
names: Similarity
messages: Belongs to the zygin family.

9305:GATA3
gene id: 9305:GATA3
uniprot id: G3X1W3
names: Subcellular Location Annotation
messages: Nucleus

9305:MAL2
gene id: 9305:MAL2
uniprot id: A0A7N4P4E4
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100913409
gene id: 9305:LOC100913409
uniprot id: G3WRV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:POLR2F
gene id: 9305:POLR2F
uniprot id: A0A7N4P280
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: Nucleus

9305:LOC100928342
gene id: 9305:LOC100928342
uniprot id: G3W913
names: Similarity
messages: Belongs to the sepiapterin reductase family.

9305:XPO6
gene id: 9305:XPO6
uniprot id: G3WLI8
uniprot id: G3WLI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

9305:ACO1
gene id: 9305:ACO1
uniprot id: A0A7N4V694
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Conversely, when cellular iron levels are high, binds a 4Fe-4S cluster which precludes RNA binding activity and promotes the aconitase activity, the isomerization of citrate to isocitrate via cis-aconitate.
messages: Interacts (when associated with the 4Fe-4S) with FBXL5. Interacts with frataxin(81-210).
messages: cytosol

9305:ITPR3
gene id: 9305:ITPR3
uniprot id: G3VVL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

9305:LOC100934965
gene id: 9305:LOC100934965
uniprot id: A0A7N4P0R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9305:ATOH7
gene id: 9305:ATOH7
uniprot id: A0A7N4NYK3
names: Subcellular Location Annotation
messages: Nucleus
messages: Perikaryon
messages: axon

9305:SRMS
gene id: 9305:SRMS
uniprot id: G3X1L2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9305:LOC100932503
gene id: 9305:LOC100932503
uniprot id: A0A7N4NVY4
names: Similarity
messages: Belongs to the FBPase class 1 family.

9305:TNFRSF21
gene id: 9305:TNFRSF21
uniprot id: G3X0M3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100916229
gene id: 9305:LOC100916229
uniprot id: G3WGH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:LTA
gene id: 9305:LTA
uniprot id: A0A7N4NZ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
messages: Homotrimer, and heterotrimer of either two LTB and one LTA subunits or (less prevalent) two LTA and one LTB subunits. Interacts with TNFRSF14.
messages: Membrane
messages: Secreted

9305:PTGDS
gene id: 9305:PTGDS
uniprot id: G3W418
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum
messages: perinuclear region

9305:HLX
gene id: 9305:HLX
uniprot id: G3WF98
names: Subcellular Location Annotation
messages: Nucleus

9305:CTNNAL1
gene id: 9305:CTNNAL1
uniprot id: A0A7N4Q105
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

9305:LOC100913363
gene id: 9305:LOC100913363
uniprot id: G3WWQ6
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

9305:SCN3B
gene id: 9305:SCN3B
uniprot id: A0A7N4UXC7
uniprot id: G3W8Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

9305:SLC12A6
gene id: 9305:SLC12A6
uniprot id: A0A7N4P0U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

9305:PSAT1
gene id: 9305:PSAT1
uniprot id: A0A7N4P4N9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

9305:MOS
gene id: 9305:MOS
uniprot id: A0A7N4PAL1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:ATF4
gene id: 9305:ATF4
uniprot id: G3WM84
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

9305:TAF1D
gene id: 9305:TAF1D
uniprot id: A0A7N4PM38
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. Interacts with UBTF.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

9305:GCLM
gene id: 9305:GCLM
uniprot id: G3VR55
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

9305:LOC100924868
gene id: 9305:LOC100924868
uniprot id: G3VI92
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:STEAP2
gene id: 9305:STEAP2
uniprot id: G3WY55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

9305:LOC100929960
gene id: 9305:LOC100929960
uniprot id: G3VMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:AGK
gene id: 9305:AGK
uniprot id: G3WYZ9
uniprot id: G3WZ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

9305:FAM83B
gene id: 9305:FAM83B
uniprot id: A0A7N4P7L5
names: Similarity
messages: Belongs to the FAM83 family.

9305:ARHGDIA
gene id: 9305:ARHGDIA
uniprot id: A0A7N4NX53
names: Similarity
messages: Belongs to the Rho GDI family.

9305:SLC46A2
gene id: 9305:SLC46A2
uniprot id: G3W3V7
names: Subcellular Location Annotation
messages: Membrane

9305:MAPK14
gene id: 9305:MAPK14
uniprot id: A0A7N4NGT3
uniprot id: G3VFI7
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

9305:LOC100917076
gene id: 9305:LOC100917076
uniprot id: A0A7N4PIH7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

9305:GDPD1
gene id: 9305:GDPD1
uniprot id: G3WYW4
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

9305:MRRF
gene id: 9305:MRRF
uniprot id: A0A7N4PBL2
uniprot id: A0A7N4UZH2
uniprot id: G3WGQ0
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

9305:NUP205
gene id: 9305:NUP205
uniprot id: A0A7N4PHX7
uniprot id: G3WNP3
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

9305:UFC1
gene id: 9305:UFC1
uniprot id: G3WVB6
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

9305:ARSL
gene id: 9305:ARSL
uniprot id: A0A7N4PR83
uniprot id: G3W3T8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9305:GBGT1
gene id: 9305:GBGT1
uniprot id: G3W2W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

9305:PTGES3
gene id: 9305:PTGES3
uniprot id: A0A7N4PNI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p23/wos2 family.
messages: Cytoplasm
messages: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation.
messages: Forms a complex with HSP70, HSP90 and other chaperones.

9305:UBA2
gene id: 9305:UBA2
uniprot id: G3VHX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

9305:LOC100917427
gene id: 9305:LOC100917427
uniprot id: A0A7N4P570
names: Subcellular Location Annotation
messages: Membrane

9305:TMCC2
gene id: 9305:TMCC2
uniprot id: G3WKV5
uniprot id: G3WKV6
names: Similarity
messages: Belongs to the TEX28 family.

9305:RHO
gene id: 9305:RHO
uniprot id: G3WKC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

9305:TSPAN31
gene id: 9305:TSPAN31
uniprot id: A0A7N4PY65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9305:LOC100933692
gene id: 9305:LOC100933692
uniprot id: A0A7N4V5E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9305:LOC105750377
gene id: 9305:LOC105750377
uniprot id: G3X3W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane

9305:HMOX2
gene id: 9305:HMOX2
uniprot id: G3VI39
names: Similarity
messages: Belongs to the heme oxygenase family.

9305:LOC100923284
gene id: 9305:LOC100923284
uniprot id: G3WJQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Interacts with FDX1/adrenodoxin.
messages: Mitochondrion inner membrane

9305:LOC100914600
gene id: 9305:LOC100914600
uniprot id: A0A7N4NSK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MCHR2
gene id: 9305:MCHR2
uniprot id: G3WNT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:KIF2C
gene id: 9305:KIF2C
uniprot id: G3WD38
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9305:CXCL9
gene id: 9305:CXCL9
uniprot id: G3VMQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9305:SMARCAD1
gene id: 9305:SMARCAD1
uniprot id: G3VE33
names: Subcellular Location Annotation
messages: Chromosome

9305:DUS3L
gene id: 9305:DUS3L
uniprot id: G3WMI6
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

9305:PSME3IP1
gene id: 9305:PSME3IP1
uniprot id: G3WM94
names: Subcellular Location Annotation
messages: Nucleus

9305:GLRB
gene id: 9305:GLRB
uniprot id: G3VXM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

9305:GNPDA1
gene id: 9305:GNPDA1
uniprot id: A0A7N4NXB3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

9305:LYZ
gene id: 9305:LYZ
uniprot id: G3VQQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

9305:MAB21L1
gene id: 9305:MAB21L1
uniprot id: A0A7N4NKM2
names: Similarity
messages: Belongs to the mab-21 family.

9305:GPR119
gene id: 9305:GPR119
uniprot id: G3WUU5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:POMK
gene id: 9305:POMK
uniprot id: G3X2V1
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

9305:IP6K3
gene id: 9305:IP6K3
uniprot id: G3W0T7
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9305:ANPEP
gene id: 9305:ANPEP
uniprot id: G3WIS7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

9305:AFF4
gene id: 9305:AFF4
uniprot id: G3WJ80
names: Similarity
messages: Belongs to the AF4 family.

9305:RPL38
gene id: 9305:RPL38
uniprot id: A0A7N4PQ00
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

9305:SPOPL
gene id: 9305:SPOPL
uniprot id: A0A7N4NTK6
names: Similarity
messages: Belongs to the Tdpoz family.

9305:STN1
gene id: 9305:STN1
uniprot id: A0A7N4Q1A6
uniprot id: A0A7N4UX52
uniprot id: G3WZ40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the STN1 family.
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

9305:BUD31
gene id: 9305:BUD31
uniprot id: G3WCW9
uniprot id: G3WCX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

9305:KIN
gene id: 9305:KIN
uniprot id: G3X0R6
names: Similarity
messages: Belongs to the KIN17 family.

9305:SFMBT2
gene id: 9305:SFMBT2
uniprot id: A0A7N4PUK6
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100935126
gene id: 9305:LOC100935126
uniprot id: G3WRG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:FGF1
gene id: 9305:FGF1
uniprot id: A0A7N4PN44
uniprot id: G3W5U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

9305:RPS19BP1
gene id: 9305:RPS19BP1
uniprot id: A0A7N4NM24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

9305:ELF4
gene id: 9305:ELF4
uniprot id: G3WSV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9305:SCFD1
gene id: 9305:SCFD1
uniprot id: G3WPR2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

9305:ADSS2
gene id: 9305:ADSS2
uniprot id: G3VCR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

9305:TXNDC5
gene id: 9305:TXNDC5
uniprot id: G3WIJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

9305:MAB21L2
gene id: 9305:MAB21L2
uniprot id: A0A7N4PFC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mab-21 family.
messages: Cytoplasm
messages: Nucleus

9305:LOC100931375
gene id: 9305:LOC100931375
uniprot id: A0A7N4V137
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC105749163
gene id: 9305:LOC105749163
uniprot id: G3VNH1
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9305:S100A1
gene id: 9305:S100A1
uniprot id: A0A7N4PUC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Mitochondrion

9305:ATP5F1B
gene id: 9305:ATP5F1B
uniprot id: G3VIJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

9305:DYDC1
gene id: 9305:DYDC1
uniprot id: G3VRZ5
uniprot id: G3VRZ8
names: Similarity
messages: Belongs to the dpy-30 family.

9305:GTF3C5
gene id: 9305:GTF3C5
uniprot id: G3VYD8
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100934161
gene id: 9305:LOC100934161
uniprot id: G3VMJ3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:ABCC8
gene id: 9305:ABCC8
uniprot id: G3WZ95
names: Subunit
messages: Interacts with KCNJ11.

9305:ANXA5
gene id: 9305:ANXA5
uniprot id: G3VRW3
names: Domain
names: Function
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

9305:SLC22A3
gene id: 9305:SLC22A3
uniprot id: G3WVY7
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

9305:LOC100923367
gene id: 9305:LOC100923367
uniprot id: A0A7N4PWF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MMUT
gene id: 9305:MMUT
uniprot id: A0A7N4PSG3
uniprot id: G3VF42
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

9305:POSTN
gene id: 9305:POSTN
uniprot id: A0A7N4NKJ8
uniprot id: G3WCH7
uniprot id: G3WCH8
names: Subcellular Location Annotation
messages: extracellular matrix

9305:GLCE
gene id: 9305:GLCE
uniprot id: A0A7N4PQJ6
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

9305:LOC100926339
gene id: 9305:LOC100926339
uniprot id: G3VSR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:AP4B1
gene id: 9305:AP4B1
uniprot id: G3WJ27
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

9305:SPDYE4
gene id: 9305:SPDYE4
uniprot id: G3VNV2
names: Similarity
messages: Belongs to the Speedy/Ringo family.

9305:CTTNBP2
gene id: 9305:CTTNBP2
uniprot id: G3X041
names: Subcellular Location Annotation
messages: cell cortex
messages: dendritic spine

9305:LOC100919855
gene id: 9305:LOC100919855
uniprot id: A0A7N4NFK9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:LYRM7
gene id: 9305:LYRM7
uniprot id: A0A7N4NKM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.
messages: Belongs to the complex I LYR family.
messages: Interacts with UQCRFS1.
messages: Mitochondrion matrix

9305:ALDH8A1
gene id: 9305:ALDH8A1
uniprot id: G3WJM1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9305:LOC100932699
gene id: 9305:LOC100932699
uniprot id: A0A7N4V5J6
names: Subcellular Location Annotation
messages: Membrane

9305:CALY
gene id: 9305:CALY
uniprot id: A0A7N4V560
names: Similarity
messages: Belongs to the NSG family.

9305:DUSP3
gene id: 9305:DUSP3
uniprot id: G3VW43
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9305:LOC100930341
gene id: 9305:LOC100930341
uniprot id: G3W499
names: Subcellular Location Annotation
messages: Membrane

9305:LOC105749409
gene id: 9305:LOC105749409
uniprot id: A0A7N4PXL3
uniprot id: G3WSP8
names: Similarity
messages: Belongs to the Bcl-2 family.

9305:TRIM3
gene id: 9305:TRIM3
uniprot id: G3VZK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

9305:SEZ6L2
gene id: 9305:SEZ6L2
uniprot id: A0A7N4Q079
uniprot id: G3W7Z1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:DHX9
gene id: 9305:DHX9
uniprot id: G3W358
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Nucleus

9305:SLCO5A1
gene id: 9305:SLCO5A1
uniprot id: G3WUN0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:LOC100918456
gene id: 9305:LOC100918456
uniprot id: A0A7N4NJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ZNF532
gene id: 9305:ZNF532
uniprot id: A0A7N4NTY6
uniprot id: G3WME9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

9305:LOC100926557
gene id: 9305:LOC100926557
uniprot id: G3WFM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100929057
gene id: 9305:LOC100929057
uniprot id: A0A7N4P3R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PCID2
gene id: 9305:PCID2
uniprot id: G3WWX0
names: Similarity
messages: Belongs to the CSN12 family.

9305:MAP2K3
gene id: 9305:MAP2K3
uniprot id: A0A7N4PJL7
uniprot id: G3WN90
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:DBR1
gene id: 9305:DBR1
uniprot id: G3VX73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

9305:DSEL
gene id: 9305:DSEL
uniprot id: A0A7N4PU93
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

9305:LOC100923285
gene id: 9305:LOC100923285
uniprot id: A0A7N4P187
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100921340
gene id: 9305:LOC100921340
uniprot id: A0A7N4Q1I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100928781
gene id: 9305:LOC100928781
uniprot id: A0A7N4PCV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

9305:FAM151B
gene id: 9305:FAM151B
uniprot id: A0A7N4V2X6
names: Similarity
messages: Belongs to the FAM151 family.

9305:LOC100926600
gene id: 9305:LOC100926600
uniprot id: A0A7N4PRX8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

9305:KCNE1
gene id: 9305:KCNE1
uniprot id: A0A7N4PDU8
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9305:TCEANC
gene id: 9305:TCEANC
uniprot id: G3W2F5
names: Subcellular Location Annotation
messages: Nucleus

9305:HMBS
gene id: 9305:HMBS
uniprot id: A0A7N4P5Q5
names: Similarity
messages: Belongs to the HMBS family.

9305:EIF3B
gene id: 9305:EIF3B
uniprot id: G3VDD6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Also interacts with UPF2. Interacts with METTL3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: The RRM domain mediates interaction with EIF3J.

9305:RNASEH1
gene id: 9305:RNASEH1
uniprot id: A0A7N4PI31
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

9305:NGB
gene id: 9305:NGB
uniprot id: G3W066
names: Similarity
messages: Belongs to the globin family.

9305:PRDX2
gene id: 9305:PRDX2
uniprot id: G3WSH0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

9305:IFIH1
gene id: 9305:IFIH1
uniprot id: G3X0K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

9305:LOC100933830
gene id: 9305:LOC100933830
uniprot id: G3VGJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:RPL26L1
gene id: 9305:RPL26L1
uniprot id: G3WCU1
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

9305:GLI3
gene id: 9305:GLI3
uniprot id: G3W7A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus

9305:PPP1R11
gene id: 9305:PPP1R11
uniprot id: A0A7N4PZ39
names: Subunit
messages: Interacts with TLR2 and UBE2D2.

9305:PDK2
gene id: 9305:PDK2
uniprot id: G3WI52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

9305:HTR1B
gene id: 9305:HTR1B
uniprot id: A0A7N4NJ94
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
messages: Homodimer. Heterodimer with HTR1D.
messages: Ligands are bound in a hydrophobic pocket formed by the transmembrane helices.
messages: Membrane
messages: Palmitoylated.
messages: Phosphorylated.

9305:ERBB2
gene id: 9305:ERBB2
uniprot id: G3WQQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

9305:MED6
gene id: 9305:MED6
uniprot id: G3X381
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

9305:DRD2
gene id: 9305:DRD2
uniprot id: G3WPM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

9305:PROM1
gene id: 9305:PROM1
uniprot id: G3X1S3
uniprot id: G3X1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

9305:LBX1
gene id: 9305:LBX1
uniprot id: G3WHH0
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100933215
gene id: 9305:LOC100933215
uniprot id: G3WIN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PLA2G2F
gene id: 9305:PLA2G2F
uniprot id: G3WH25
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9305:LOC100927323
gene id: 9305:LOC100927323
uniprot id: G3WTI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CDC6
gene id: 9305:CDC6
uniprot id: A0A7N4NX35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
messages: Nucleus

9305:ENY2
gene id: 9305:ENY2
uniprot id: A0A7N4NJI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3. TREX-2 contains 2 ENY2 chains. The TREX-2 complex interacts with the nucleoporin NUP153. Component of some SAGA transcription coactivator-HAT complexes, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ENY2, ATXN7, ATXN7L3, and USP22 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with ATXN7L3, GANP and with the RNA polymerase II. Interacts strongly with ATXN7L3 and ATXN7L3B.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

9305:PLSCR1
gene id: 9305:PLSCR1
uniprot id: G3WXY4
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

9305:WASF3
gene id: 9305:WASF3
uniprot id: G3WKI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

9305:SDHD
gene id: 9305:SDHD
uniprot id: A0A7N4PK29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

9305:ST3GAL2
gene id: 9305:ST3GAL2
uniprot id: A0A7N4UWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9305:ISM1
gene id: 9305:ISM1
uniprot id: A0A7N4NHS7
names: Similarity
messages: Belongs to the isthmin family.

9305:LOC100934607
gene id: 9305:LOC100934607
uniprot id: A0A7N4Q1K1
uniprot id: G3WEJ5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:APMAP
gene id: 9305:APMAP
uniprot id: G3VIF2
names: Similarity
messages: Belongs to the strictosidine synthase family.

9305:HHIPL2
gene id: 9305:HHIPL2
uniprot id: G3VZT1
names: Similarity
messages: Belongs to the HHIP family.

9305:CMC2
gene id: 9305:CMC2
uniprot id: A0A7N4V5E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

9305:VSX1
gene id: 9305:VSX1
uniprot id: A0A7N4V0P5
names: Subcellular Location Annotation
messages: Nucleus

9305:GPRC6A
gene id: 9305:GPRC6A
uniprot id: G3W3X2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:HTR7
gene id: 9305:HTR7
uniprot id: G3W0X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:DIS3
gene id: 9305:DIS3
uniprot id: A0A7N4PTT5
uniprot id: G3WQZ4
names: Similarity
messages: Belongs to the RNR ribonuclease family.

9305:IFT46
gene id: 9305:IFT46
uniprot id: G3WGE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT46 family.
messages: cilium
messages: cilium basal body

9305:ENKUR
gene id: 9305:ENKUR
uniprot id: G3WWY9
names: Subcellular Location Annotation
messages: cilium axoneme

9305:LOC100934510
gene id: 9305:LOC100934510
uniprot id: A0A7N4NFU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:KATNA1
gene id: 9305:KATNA1
uniprot id: G3WY86
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and DCAF1 proteins (EDVP complex). Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42. Interacts with KATNB1 and KATNBL1. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Midbody
messages: Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation.
messages: The N-terminus is sufficient for interaction with microtubules, although high affinity binding to microtubules also requires an intact C-terminal domain and ATP, which promotes oligomerization.
messages: Ubiquitinated by the BCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation. Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted for proteasomal degradation.
messages: centrosome
messages: spindle
messages: spindle pole

9305:EGFL6
gene id: 9305:EGFL6
uniprot id: G3W3J1
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:KCNK18
gene id: 9305:KCNK18
uniprot id: G3WW85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9305:LOC100920925
gene id: 9305:LOC100920925
uniprot id: G3VT84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:GNRH1
gene id: 9305:GNRH1
uniprot id: A0A7N4NUM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.

9305:PDCL3
gene id: 9305:PDCL3
uniprot id: A0A7N4P8M6
names: Similarity
messages: Belongs to the phosducin family.

9305:LOC100922565
gene id: 9305:LOC100922565
uniprot id: G3W0P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ADM
gene id: 9305:ADM
uniprot id: A0A7N4NM04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

9305:LOC100929922
gene id: 9305:LOC100929922
uniprot id: A0A7N4NSJ6
names: Subcellular Location Annotation
messages: Membrane

9305:AGXT
gene id: 9305:AGXT
uniprot id: A0A7N4P6E7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Peroxisome

9305:B9D1
gene id: 9305:B9D1
uniprot id: G3WJF3
names: Subcellular Location Annotation
messages: cilium basal body

9305:BCDIN3D
gene id: 9305:BCDIN3D
uniprot id: G3WBR1
names: Similarity
messages: Belongs to the methyltransferase superfamily.

9305:LOC100925873
gene id: 9305:LOC100925873
uniprot id: A0A7N4NHP2
uniprot id: G3VJC1
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:PANX1
gene id: 9305:PANX1
uniprot id: G3X191
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: S-nitrosylation inhibits channel currents and ATP release.
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

9305:BAG6
gene id: 9305:BAG6
uniprot id: A0A7N4NRL6
uniprot id: G3VSS5
names: Subcellular Location Annotation
messages: Nucleus
messages: extracellular exosome

9305:CNN2
gene id: 9305:CNN2
uniprot id: A0A7N4P186
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

9305:CRYBG1
gene id: 9305:CRYBG1
uniprot id: G3WI39
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

9305:TUBE1
gene id: 9305:TUBE1
uniprot id: G3WLJ8
names: Similarity
messages: Belongs to the tubulin family.

9305:SLC37A1
gene id: 9305:SLC37A1
uniprot id: G3WSH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
messages: Membrane

9305:PEMT
gene id: 9305:PEMT
uniprot id: A0A7N4NTH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

9305:PTGIS
gene id: 9305:PTGIS
uniprot id: G3VRG3
uniprot id: G3VRG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

9305:NR2F2
gene id: 9305:NR2F2
uniprot id: A0A7N4NYS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9305:KCNS3
gene id: 9305:KCNS3
uniprot id: A0A7N4NNF9
uniprot id: G3VE71
names: Subcellular Location Annotation
messages: Membrane

9305:GPR171
gene id: 9305:GPR171
uniprot id: A0A7N4PQW7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:PPP1R14C
gene id: 9305:PPP1R14C
uniprot id: G3X024
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Inhibitor of PPP1CA.
messages: Membrane

9305:GABARAPL1
gene id: 9305:GABARAPL1
uniprot id: A0A7N4NX16
names: Similarity
messages: Belongs to the ATG8 family.

9305:LOC100935017
gene id: 9305:LOC100935017
uniprot id: G3VLW3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

9305:C2H10orf53
gene id: 9305:C2H10orf53
uniprot id: A0A7N4NLZ3
names: Similarity
messages: Belongs to the UPF0728 family.

9305:LOC100919756
gene id: 9305:LOC100919756
uniprot id: G3WP57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MEOX1
gene id: 9305:MEOX1
uniprot id: A0A7N4PRU8
uniprot id: G3W2Z8
names: Subcellular Location Annotation
messages: Nucleus

9305:LTV1
gene id: 9305:LTV1
uniprot id: G3WQC6
names: Similarity
messages: Belongs to the LTV1 family.

9305:SUMF2
gene id: 9305:SUMF2
uniprot id: A0A7N4P8U8
uniprot id: G3W5U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

9305:ARSK
gene id: 9305:ARSK
uniprot id: G3WFM9
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9305:SLC25A19
gene id: 9305:SLC25A19
uniprot id: A0A7N4P2Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9305:LOC100926104
gene id: 9305:LOC100926104
uniprot id: G3WJ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

9305:SNRPD1
gene id: 9305:SNRPD1
uniprot id: G3WED5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP core protein family.
messages: Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Most spliceosomal snRNPs contain a common set of Sm proteins, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. Component of the U1 snRNP. The U1 snRNP is composed of the U1 snRNA and the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG, and at least three U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39, plus LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Part of the SMN-Sm complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8, STRAP/UNRIP and the Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG; catalyzes core snRNPs assembly. Forms a 6S pICln-Sm complex composed of CLNS1A/pICln, SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG; ring-like structure where CLNS1A/pICln mimics additional Sm proteins and which is unable to assemble into the core snRNP.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.
messages: cytosol

9305:LOC100916277
gene id: 9305:LOC100916277
uniprot id: G3VDQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100919131
gene id: 9305:LOC100919131
uniprot id: G3WER9
names: Similarity
messages: Belongs to the globin family.

9305:RSPO3
gene id: 9305:RSPO3
uniprot id: A0A7N4PHE7
names: Similarity
messages: Belongs to the R-spondin family.

9305:LOC100924949
gene id: 9305:LOC100924949
uniprot id: G3VGV6
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

9305:TNFSF8
gene id: 9305:TNFSF8
uniprot id: G3W2K3
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9305:CHST12
gene id: 9305:CHST12
uniprot id: A0A7N4UY58
uniprot id: G3VUI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:HLF
gene id: 9305:HLF
uniprot id: A0A7N4P5Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

9305:DLGAP4
gene id: 9305:DLGAP4
uniprot id: A0A7N4PRK0
names: Similarity
messages: Belongs to the SAPAP family.

9305:CLTB
gene id: 9305:CLTB
uniprot id: A0A7N4UY97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

9305:SLC6A15
gene id: 9305:SLC6A15
uniprot id: G3VKX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9305:LOC100915337
gene id: 9305:LOC100915337
uniprot id: G3VJJ7
names: Subcellular Location Annotation
messages: Membrane

9305:CLK1
gene id: 9305:CLK1
uniprot id: G3WGP6
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:CAMLG
gene id: 9305:CAMLG
uniprot id: G3WPA4
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.

9305:P2RY8
gene id: 9305:P2RY8
uniprot id: A0A7N4V018
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:LHCGR
gene id: 9305:LHCGR
uniprot id: G3WP77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

9305:MS4A1
gene id: 9305:MS4A1
uniprot id: G3VYV0
names: Similarity
messages: Belongs to the MS4A family.

9305:SRPX
gene id: 9305:SRPX
uniprot id: G3VGE3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:TBX15
gene id: 9305:TBX15
uniprot id: G3WHS9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9305:BPIFC
gene id: 9305:BPIFC
uniprot id: G3WUX4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

9305:MOCS2
gene id: 9305:MOCS2
uniprot id: G3VIP0
uniprot id: G3VIP1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein is produced by a bicistronic gene which also produces the small subunit (MOCS2A) from an overlapping reading frame.
messages: cytosol

9305:CCZ1
gene id: 9305:CCZ1
uniprot id: G3WN95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCZ1 family.
messages: Lysosome membrane

9305:MS4A5
gene id: 9305:MS4A5
uniprot id: A0A7N4NUX3
names: Similarity
messages: Belongs to the MS4A family.

9305:LOC100920543
gene id: 9305:LOC100920543
uniprot id: G3W2L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:HPS3
gene id: 9305:HPS3
uniprot id: G5EA74
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: Cytoplasm
messages: Involved in early stages of melanosome biogenesis and maturation.

9305:SLC7A10
gene id: 9305:SLC7A10
uniprot id: G3WRY9
names: Subcellular Location Annotation
messages: Membrane

9305:SGK2
gene id: 9305:SGK2
uniprot id: G3VL16
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:PFDN6
gene id: 9305:PFDN6
uniprot id: A0A7N4P5I5
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

9305:LOC100924919
gene id: 9305:LOC100924919
uniprot id: G3VTI3
uniprot id: G3W1M2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

9305:LOC100924253
gene id: 9305:LOC100924253
uniprot id: A0A7N4NTJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CDK2
gene id: 9305:CDK2
uniprot id: G3W161
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:TMEM126B
gene id: 9305:TMEM126B
uniprot id: A0A7N4PBU8
names: Subcellular Location Annotation
messages: Membrane

9305:SDHC
gene id: 9305:SDHC
uniprot id: A0A7N4Q1P4
uniprot id: G3WWM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

9305:LOC100915852
gene id: 9305:LOC100915852
uniprot id: G3VQC3
names: Subcellular Location Annotation
messages: Membrane

9305:PKNOX1
gene id: 9305:PKNOX1
uniprot id: G3WWP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

9305:AGTR2
gene id: 9305:AGTR2
uniprot id: G3W2S8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MTUS1.
messages: Membrane

9305:LOC100933884
gene id: 9305:LOC100933884
uniprot id: A0A7N4V4U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9305:RAF1
gene id: 9305:RAF1
uniprot id: G3WC19
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

9305:ATG5
gene id: 9305:ATG5
uniprot id: A0A7N4P876
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

9305:LOC100934104
gene id: 9305:LOC100934104
uniprot id: G3W1J2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

9305:LOC100930816
gene id: 9305:LOC100930816
uniprot id: A0A7N4NMX1
names: Subcellular Location Annotation
messages: Nucleus

9305:ND4
gene id: 9305:ND4
uniprot id: J9RRN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

9305:TRMT6
gene id: 9305:TRMT6
uniprot id: G3WAV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRM6/GCD10 family.
messages: Nucleus

9305:CCM2L
gene id: 9305:CCM2L
uniprot id: G3WF83
names: Similarity
messages: Belongs to the CCM2 family.

9305:ADORA1
gene id: 9305:ADORA1
uniprot id: G3WUH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

9305:LIX1
gene id: 9305:LIX1
uniprot id: G3VU47
names: Similarity
messages: Belongs to the LIX1 family.

9305:GLA
gene id: 9305:GLA
uniprot id: G3WK18
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

9305:ELF3
gene id: 9305:ELF3
uniprot id: G3VD68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9305:STAT5B
gene id: 9305:STAT5B
uniprot id: G3VMK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9305:SERPINA12
gene id: 9305:SERPINA12
uniprot id: G3VP32
names: Similarity
messages: Belongs to the serpin family.

9305:GNB3
gene id: 9305:GNB3
uniprot id: G3WTV2
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

9305:TTC39A
gene id: 9305:TTC39A
uniprot id: A0A7N4Q104
uniprot id: G3W3Q1
names: Similarity
messages: Belongs to the TTC39 family.

9305:LOC100925102
gene id: 9305:LOC100925102
uniprot id: A0A7N4PQC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9305:MRPL17
gene id: 9305:MRPL17
uniprot id: A0A7N4PGL9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

9305:CCT2
gene id: 9305:CCT2
uniprot id: G3VSN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

9305:CACNG2
gene id: 9305:CACNG2
uniprot id: A0A7N4NM71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

9305:CNR1
gene id: 9305:CNR1
uniprot id: A0A7N4NY62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Signaling typically involves reduction in cyclic AMP.
messages: Interacts (via C-terminus) with CNRIP1.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

9305:LOC100931920
gene id: 9305:LOC100931920
uniprot id: A0A7N4NRE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ACTC1
gene id: 9305:ACTC1
uniprot id: A0A7N4PH39
names: Similarity
messages: Belongs to the actin family.

9305:LOC100925098
gene id: 9305:LOC100925098
uniprot id: G3WDR0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.

9305:PRKCD
gene id: 9305:PRKCD
uniprot id: G3W312
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

9305:TMEM54
gene id: 9305:TMEM54
uniprot id: G3WGH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

9305:LOC100916252
gene id: 9305:LOC100916252
uniprot id: G3VKF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:GCM2
gene id: 9305:GCM2
uniprot id: G3WAA7
names: Subcellular Location Annotation
messages: Nucleus

9305:SDR42E1
gene id: 9305:SDR42E1
uniprot id: G3WH03
names: Similarity
messages: Belongs to the 3-beta-HSD family.

9305:STK38L
gene id: 9305:STK38L
uniprot id: A0A7N4NS21
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:AKAP8
gene id: 9305:AKAP8
uniprot id: A0A7N4V752
uniprot id: G3W9H9
names: Similarity
messages: Belongs to the AKAP95 family.

9305:NKX6-1
gene id: 9305:NKX6-1
uniprot id: A0A7N4P550
names: Subcellular Location Annotation
messages: Nucleus

9305:PIGO
gene id: 9305:PIGO
uniprot id: A0A7N4V7P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:C7
gene id: 9305:C7
uniprot id: G3WK51
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:COG2
gene id: 9305:COG2
uniprot id: G3WZ34
names: Similarity
messages: Belongs to the COG2 family.

9305:PDYN
gene id: 9305:PDYN
uniprot id: G3WIV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
messages: Secreted

9305:MYH11
gene id: 9305:MYH11
uniprot id: G3VZB7
uniprot id: G3VZB8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9305:RPA2
gene id: 9305:RPA2
uniprot id: G3WRB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

9305:ACTB
gene id: 9305:ACTB
uniprot id: A0A7N4PW14
names: Similarity
messages: Belongs to the actin family.

9305:SRD5A1
gene id: 9305:SRD5A1
uniprot id: A0A7N4PNE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

9305:MRPL4
gene id: 9305:MRPL4
uniprot id: G3W356
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

9305:F13A1
gene id: 9305:F13A1
uniprot id: G3WM90
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9305:EHD3
gene id: 9305:EHD3
uniprot id: A0A7N4P5J3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

9305:CCNE2
gene id: 9305:CCNE2
uniprot id: A0A7N4NTD7
names: Similarity
messages: Belongs to the cyclin family. Cyclin E subfamily.

9305:LOC100918627
gene id: 9305:LOC100918627
uniprot id: G3W3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100921188
gene id: 9305:LOC100921188
uniprot id: A0A7N4NNQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100922176
gene id: 9305:LOC100922176
uniprot id: A0A7N4PGK5
names: Subcellular Location Annotation
messages: Membrane

9305:CHMP7
gene id: 9305:CHMP7
uniprot id: A0A7N4PN67
names: Similarity
messages: Belongs to the SNF7 family.

9305:ATP6V1A
gene id: 9305:ATP6V1A
uniprot id: G3VZS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: clathrin-coated vesicle membrane
messages: secretory vesicle

9305:FTO
gene id: 9305:FTO
uniprot id: A0A7N4NFL0
uniprot id: G3W5C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

9305:SLC19A3
gene id: 9305:SLC19A3
uniprot id: A0A7N4V5F8
uniprot id: G3W9D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

9305:TMOD4
gene id: 9305:TMOD4
uniprot id: G3WLA6
names: Subcellular Location Annotation
messages: cytoskeleton

9305:KYNU
gene id: 9305:KYNU
uniprot id: G3W586
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100919806
gene id: 9305:LOC100919806
uniprot id: G3VUR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:P2RY4
gene id: 9305:P2RY4
uniprot id: G3VUB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:SLC15A2
gene id: 9305:SLC15A2
uniprot id: G3W3P9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

9305:GKAP1
gene id: 9305:GKAP1
uniprot id: A0A7N4PFU8
uniprot id: A0A7N4PYG4
uniprot id: G3WYY7
names: Similarity
messages: Belongs to the GKAP1 family.

9305:PPM1G
gene id: 9305:PPM1G
uniprot id: G3WKM5
names: Similarity
messages: Belongs to the PP2C family.

9305:TOP2A
gene id: 9305:TOP2A
uniprot id: G3WFK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

9305:MED4
gene id: 9305:MED4
uniprot id: A0A7N4NN52
uniprot id: G3VS79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9305:LOC100923720
gene id: 9305:LOC100923720
uniprot id: A0A7N4PDZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:GMNN
gene id: 9305:GMNN
uniprot id: A0A7N4PAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

9305:HDDC2
gene id: 9305:HDDC2
uniprot id: A0A7N4NZA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

9305:NPY
gene id: 9305:NPY
uniprot id: G3W5E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

9305:CEP57
gene id: 9305:CEP57
uniprot id: A0A7N4V770
names: Similarity
messages: Belongs to the translokin family.

9305:SGCD
gene id: 9305:SGCD
uniprot id: G3WIA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

9305:SPON2
gene id: 9305:SPON2
uniprot id: G3WG82
names: Subcellular Location Annotation
messages: extracellular matrix

9305:NUBP2
gene id: 9305:NUBP2
uniprot id: A0A7N4PKD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.
messages: Nucleus
messages: centrosome

9305:TFDP1
gene id: 9305:TFDP1
uniprot id: G3WQY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9305:LOC100928381
gene id: 9305:LOC100928381
uniprot id: A0A7N4PYV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9305:LOC100932442
gene id: 9305:LOC100932442
uniprot id: A0A7N4V3C4
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

9305:GFRA2
gene id: 9305:GFRA2
uniprot id: G3WYE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

9305:C3H2orf88
gene id: 9305:C3H2orf88
uniprot id: A0A7N4P728
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small membrane AKAP family.
messages: Cell membrane
messages: Membrane

9305:SLC2A2
gene id: 9305:SLC2A2
uniprot id: G3WFV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane

9305:LACTB2
gene id: 9305:LACTB2
uniprot id: G3WJP4
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

9305:STC2
gene id: 9305:STC2
uniprot id: A0A7N4PI81
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

9305:ZCCHC17
gene id: 9305:ZCCHC17
uniprot id: A0A7N4PR70
names: Subcellular Location Annotation
messages: nucleolus

9305:LOC100915440
gene id: 9305:LOC100915440
uniprot id: A0A7N4P2A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9305:HOXB5
gene id: 9305:HOXB5
uniprot id: A0A7N4NIW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9305:SLC39A7
gene id: 9305:SLC39A7
uniprot id: A0A7N4PU98
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100925549
gene id: 9305:LOC100925549
uniprot id: A0A7N4NI61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:DHX58
gene id: 9305:DHX58
uniprot id: G3VV49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

9305:ACTL7A
gene id: 9305:ACTL7A
uniprot id: G3W6D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Golgi apparatus
messages: May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis.
messages: Nucleus
messages: cytoskeleton

9305:LOC100913189
gene id: 9305:LOC100913189
uniprot id: A0A7N4P099
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100921514
gene id: 9305:LOC100921514
uniprot id: G3W9U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:YIPF5
gene id: 9305:YIPF5
uniprot id: G3VN34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

9305:CDKN1B
gene id: 9305:CDKN1B
uniprot id: A0A7N4PB29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDI family.
messages: Cytoplasm
messages: Endosome
messages: Nucleus

9305:WNT10B
gene id: 9305:WNT10B
uniprot id: G3VID6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9305:MEGF10
gene id: 9305:MEGF10
uniprot id: G3WDB2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:VPS45
gene id: 9305:VPS45
uniprot id: G3VWS6
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

9305:UPK1B
gene id: 9305:UPK1B
uniprot id: G3VIT7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Heterodimer with uroplakin-3A (UPK3A) or uroplakin-3B (UPK3B).
messages: Membrane

9305:SMC3
gene id: 9305:SMC3
uniprot id: G3WLM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

9305:IRF1
gene id: 9305:IRF1
uniprot id: G3W5G7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9305:RHBDF2
gene id: 9305:RHBDF2
uniprot id: G3WUB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

9305:FAM167A
gene id: 9305:FAM167A
uniprot id: A0A7N4P995
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

9305:ABHD12
gene id: 9305:ABHD12
uniprot id: A0A7N4UZJ0
uniprot id: G3WYT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serine esterase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:LOC100931633
gene id: 9305:LOC100931633
uniprot id: G3VRS4
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

9305:ADAM15
gene id: 9305:ADAM15
uniprot id: A0A7N4NL81
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:CNIH1
gene id: 9305:CNIH1
uniprot id: G3W593
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

9305:TCN1
gene id: 9305:TCN1
uniprot id: G3VY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

9305:IKBKB
gene id: 9305:IKBKB
uniprot id: G3WZY2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9305:SHOX
gene id: 9305:SHOX
uniprot id: A0A7N4P7Q7
names: Subcellular Location Annotation
messages: Nucleus

9305:TRIM46
gene id: 9305:TRIM46
uniprot id: A0A7N4V4P3
uniprot id: G3VZK9
names: Subcellular Location Annotation
messages: cytoskeleton

9305:SGCB
gene id: 9305:SGCB
uniprot id: A0A7N4PGL3
uniprot id: G3WZR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The association between SGCB and SGCG is particularly strong while SGCA is loosely associated with the other sarcoglycans.
messages: cytoskeleton
messages: sarcolemma

9305:NUBP1
gene id: 9305:NUBP1
uniprot id: G3W2D6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Cell projection
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.

9305:DRAM1
gene id: 9305:DRAM1
uniprot id: A0A7N4PF60
names: Subcellular Location Annotation
messages: Membrane

9305:MYOZ1
gene id: 9305:MYOZ1
uniprot id: G3VXA0
names: Similarity
messages: Belongs to the myozenin family.

9305:F3
gene id: 9305:F3
uniprot id: G3W1I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

9305:LOC100925532
gene id: 9305:LOC100925532
uniprot id: G3VM30
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:DUSP26
gene id: 9305:DUSP26
uniprot id: A0A7N4PMD8
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

9305:MCM3
gene id: 9305:MCM3
uniprot id: A0A7N4V2M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

9305:DOC2A
gene id: 9305:DOC2A
uniprot id: G3W9J1
names: Subcellular Location Annotation
messages: Membrane

9305:BTG4
gene id: 9305:BTG4
uniprot id: A0A7N4P564
names: Similarity
messages: Belongs to the BTG family.

9305:SEPTIN12
gene id: 9305:SEPTIN12
uniprot id: G3VY57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9305:LOC100929561
gene id: 9305:LOC100929561
uniprot id: G3VVF6
names: Subcellular Location Annotation
messages: Membrane

9305:RAD51D
gene id: 9305:RAD51D
uniprot id: G3VPQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.
messages: Nucleus

9305:LOC100931394
gene id: 9305:LOC100931394
uniprot id: G3W6Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TLCD3A
gene id: 9305:TLCD3A
uniprot id: A0A7N4PXJ8
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100917912
gene id: 9305:LOC100917912
uniprot id: G3VJQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100919316
gene id: 9305:LOC100919316
uniprot id: G3VFK8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

9305:LOC100921257
gene id: 9305:LOC100921257
uniprot id: G3WAF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MAPK13
gene id: 9305:MAPK13
uniprot id: G3VTJ1
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Interacts with MAPK8IP2.

9305:NDUFB10
gene id: 9305:NDUFB10
uniprot id: G3WR40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

9305:CLCN4
gene id: 9305:CLCN4
uniprot id: G3WSV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

9305:SLC5A2
gene id: 9305:SLC5A2
uniprot id: G3WLY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9305:LOC100920106
gene id: 9305:LOC100920106
uniprot id: G3VPX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LHX1
gene id: 9305:LHX1
uniprot id: G3W9N9
names: Subcellular Location Annotation
messages: Nucleus

9305:AEBP1
gene id: 9305:AEBP1
uniprot id: G3WNF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

9305:CIAO2A
gene id: 9305:CIAO2A
uniprot id: A0A7N4NVL5
names: Similarity
messages: Belongs to the MIP18 family.

9305:DLL1
gene id: 9305:DLL1
uniprot id: G3WP27
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

9305:LOC100932646
gene id: 9305:LOC100932646
uniprot id: A0A7N4NXW5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

9305:CNDP2
gene id: 9305:CNDP2
uniprot id: G3W6F7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

9305:PLAC8
gene id: 9305:PLAC8
uniprot id: A0A7N4NHA1
uniprot id: G3W0J4
names: Similarity
messages: Belongs to the cornifelin family.

9305:MZT1
gene id: 9305:MZT1
uniprot id: A0A7N4NX51
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the centrosome.

9305:SLC35E3
gene id: 9305:SLC35E3
uniprot id: A0A7N4UXP8
names: Subcellular Location Annotation
messages: Membrane

9305:KCNH3
gene id: 9305:KCNH3
uniprot id: G3W2R5
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

9305:LOC100915609
gene id: 9305:LOC100915609
uniprot id: G3WFI1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

9305:KRT8
gene id: 9305:KRT8
uniprot id: G3VJ06
names: Similarity
messages: Belongs to the intermediate filament family.

9305:GAST
gene id: 9305:GAST
uniprot id: G3VSY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
messages: Secreted

9305:LOC100919597
gene id: 9305:LOC100919597
uniprot id: G3VJN7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:CAPN5
gene id: 9305:CAPN5
uniprot id: G3W892
names: Similarity
messages: Belongs to the peptidase C2 family.

9305:UBE2T
gene id: 9305:UBE2T
uniprot id: G3WJY5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9305:DLK1
gene id: 9305:DLK1
uniprot id: G3W4W8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100926738
gene id: 9305:LOC100926738
uniprot id: G3W2E5
names: Subcellular Location Annotation
messages: Membrane

9305:FHL5
gene id: 9305:FHL5
uniprot id: G3WRC5
names: Function
names: Subcellular Location Annotation
messages: May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
messages: Nucleus

9305:EDN3
gene id: 9305:EDN3
uniprot id: G3WC75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

9305:KIAA1324L
gene id: 9305:KIAA1324L
uniprot id: G3X339
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

9305:LOC100918073
gene id: 9305:LOC100918073
uniprot id: G3VUD2
names: Similarity
messages: Belongs to the RIB43A family.

9305:LOC100926426
gene id: 9305:LOC100926426
uniprot id: G3VE07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:FRZB
gene id: 9305:FRZB
uniprot id: G3VWL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

9305:INHBE
gene id: 9305:INHBE
uniprot id: G3VWI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

9305:AGPAT3
gene id: 9305:AGPAT3
uniprot id: G3W425
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9305:TUBB
gene id: 9305:TUBB
uniprot id: A0A7N4PPV2
uniprot id: G3W109
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9305:PCK1
gene id: 9305:PCK1
uniprot id: G3WHW0
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

9305:LOC100931874
gene id: 9305:LOC100931874
uniprot id: G3VQK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MEIS1
gene id: 9305:MEIS1
uniprot id: G3WVM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

9305:LOC100934209
gene id: 9305:LOC100934209
uniprot id: A0A7N4PX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:EIF2B2
gene id: 9305:EIF2B2
uniprot id: A0A7N4V241
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

9305:RBM47
gene id: 9305:RBM47
uniprot id: A0A7N4PAM2
uniprot id: G3WZ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Nucleus

9305:SUB1
gene id: 9305:SUB1
uniprot id: G3WQE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Homodimer. Interacts with CSTF2.
messages: Nucleus

9305:CSN2
gene id: 9305:CSN2
uniprot id: G3VIN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-casein family.
messages: Important role in determination of the surface properties of the casein micelles.
messages: Secreted

9305:NKIRAS1
gene id: 9305:NKIRAS1
uniprot id: A0A7N4NKM7
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

9305:COQ7
gene id: 9305:COQ7
uniprot id: G3X113
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

9305:CHURC1
gene id: 9305:CHURC1
uniprot id: A0A7N4PPV1
names: Similarity
messages: Belongs to the Churchill family.

9305:SPINK4
gene id: 9305:SPINK4
uniprot id: G3W7N4
names: Subcellular Location Annotation
messages: Secreted

9305:LOC100929883
gene id: 9305:LOC100929883
uniprot id: A0A7N4PER7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

9305:GPR18
gene id: 9305:GPR18
uniprot id: G3WFL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

9305:DSC2
gene id: 9305:DSC2
uniprot id: G3W7D8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

9305:CHRM3
gene id: 9305:CHRM3
uniprot id: G3WNI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

9305:CDX2
gene id: 9305:CDX2
uniprot id: G3X060
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

9305:LOC100934385
gene id: 9305:LOC100934385
uniprot id: G3WEE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100934449
gene id: 9305:LOC100934449
uniprot id: G3VX59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9305:EIF5A
gene id: 9305:EIF5A
uniprot id: G3VY46
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

9305:LMX1B
gene id: 9305:LMX1B
uniprot id: G3W872
names: Subcellular Location Annotation
messages: Nucleus

9305:TM2D3
gene id: 9305:TM2D3
uniprot id: A0A7N4PMQ8
names: Subcellular Location Annotation
messages: Membrane

9305:UNC50
gene id: 9305:UNC50
uniprot id: G3W5H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

9305:LOC100920067
gene id: 9305:LOC100920067
uniprot id: A0A7N4P4I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:FAN1
gene id: 9305:FAN1
uniprot id: G3WVX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

9305:KCNK1
gene id: 9305:KCNK1
uniprot id: G3WDN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

9305:MFSD11
gene id: 9305:MFSD11
uniprot id: G3VT39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

9305:ECHS1
gene id: 9305:ECHS1
uniprot id: G3WB21
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

9305:CTSS
gene id: 9305:CTSS
uniprot id: G3WEW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9305:TLCD5
gene id: 9305:TLCD5
uniprot id: A0A7N4PUA3
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100921024
gene id: 9305:LOC100921024
uniprot id: G3WC29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:EEF2KMT
gene id: 9305:EEF2KMT
uniprot id: G3WIA7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.

9305:LAMA1
gene id: 9305:LAMA1
uniprot id: G3W7Z3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

9305:SEPHS1
gene id: 9305:SEPHS1
uniprot id: G3WRE8
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

9305:BPGM
gene id: 9305:BPGM
uniprot id: A0A7N4V4D3
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

9305:SLITRK1
gene id: 9305:SLITRK1
uniprot id: G3VKJ3
names: Similarity
messages: Belongs to the SLITRK family.

9305:POU5F1
gene id: 9305:POU5F1
uniprot id: G3VJ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-5 subfamily.
messages: Nucleus

9305:CD68
gene id: 9305:CD68
uniprot id: G3WSZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

9305:ZPBP2
gene id: 9305:ZPBP2
uniprot id: G3WNZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted

9305:GDF5
gene id: 9305:GDF5
uniprot id: G3X2G9
names: Similarity
messages: Belongs to the TGF-beta family.

9305:ANXA1
gene id: 9305:ANXA1
uniprot id: G3W8D2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium
messages: extracellular exosome
messages: extracellular space
messages: phagocytic cup
messages: secretory vesicle lumen

9305:THBS4
gene id: 9305:THBS4
uniprot id: G3W8V6
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:FERMT1
gene id: 9305:FERMT1
uniprot id: G3W6M7
names: Similarity
messages: Belongs to the kindlin family.

9305:CFDP1
gene id: 9305:CFDP1
uniprot id: A0A7N4V362
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

9305:MTIF2
gene id: 9305:MTIF2
uniprot id: G3VPE4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

9305:TADA3
gene id: 9305:TADA3
uniprot id: A0A7N4NSJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

9305:PAIP2
gene id: 9305:PAIP2
uniprot id: A0A7N4PTA8
names: Similarity
messages: Belongs to the PAIP2 family.

9305:YARS1
gene id: 9305:YARS1
uniprot id: A0A7N4V156
uniprot id: G3WEK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus

9305:RXRG
gene id: 9305:RXRG
uniprot id: A0A7N4V348
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

9305:OLA1
gene id: 9305:OLA1
uniprot id: A0A7N4PU27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: nucleolus

9305:RPS14
gene id: 9305:RPS14
uniprot id: A0A7N4PRZ8
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

9305:SLC29A3
gene id: 9305:SLC29A3
uniprot id: G3W5U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

9305:CCDC93
gene id: 9305:CCDC93
uniprot id: G3X323
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC93 family.
messages: Early endosome

9305:ODF2
gene id: 9305:ODF2
uniprot id: A0A7N4NI14
uniprot id: G3X391
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

9305:SCOC
gene id: 9305:SCOC
uniprot id: A0A7N4PXI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

9305:SNX20
gene id: 9305:SNX20
uniprot id: G3X3U9
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

9305:IMMP1L
gene id: 9305:IMMP1L
uniprot id: A0A7N4PUF5
uniprot id: G3WRU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

9305:NTSR1
gene id: 9305:NTSR1
uniprot id: A0A7N4V7R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ETS1
gene id: 9305:ETS1
uniprot id: A0A7N4NYM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Cytoplasm
messages: Nucleus

9305:FSCN1
gene id: 9305:FSCN1
uniprot id: G3VLI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

9305:DDX52
gene id: 9305:DDX52
uniprot id: G3WLV5
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.

9305:LOC100918140
gene id: 9305:LOC100918140
uniprot id: A0A7N4P0K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:UGP2
gene id: 9305:UGP2
uniprot id: A0A7N4NI68
uniprot id: G3VK12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

9305:TLR8
gene id: 9305:TLR8
uniprot id: A0A7N4PZA7
uniprot id: G3WLZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9305:TRMT5
gene id: 9305:TRMT5
uniprot id: A0A7N4PEC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

9305:GPR132
gene id: 9305:GPR132
uniprot id: G3VL42
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:GFRA3
gene id: 9305:GFRA3
uniprot id: G3WCY4
names: Similarity
messages: Belongs to the GDNFR family.

9305:PTTG1
gene id: 9305:PTTG1
uniprot id: A0A7N4NQL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

9305:LOC100924464
gene id: 9305:LOC100924464
uniprot id: A0A7N4UZB6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

9305:MRPL47
gene id: 9305:MRPL47
uniprot id: G3WY60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

9305:PAPSS1
gene id: 9305:PAPSS1
uniprot id: G3W5D5
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

9305:LOC100916556
gene id: 9305:LOC100916556
uniprot id: G3VP65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9305:SLC7A8
gene id: 9305:SLC7A8
uniprot id: G3WMM0
names: Subcellular Location Annotation
messages: Membrane

9305:PDX1
gene id: 9305:PDX1
uniprot id: G3X001
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9305:DNASE2B
gene id: 9305:DNASE2B
uniprot id: G3WZP0
names: Similarity
messages: Belongs to the DNase II family.

9305:LOC100916701
gene id: 9305:LOC100916701
uniprot id: G3WPA7
names: Similarity
messages: Belongs to the 2-5A synthase family.

9305:AURKA
gene id: 9305:AURKA
uniprot id: A0A7N4Q0Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centrosome

9305:KIF20B
gene id: 9305:KIF20B
uniprot id: G3WKT2
uniprot id: G3WKT3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9305:C8G
gene id: 9305:C8G
uniprot id: A0A7N4PBE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

9305:GNRHR
gene id: 9305:GNRHR
uniprot id: G3W0T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100914286
gene id: 9305:LOC100914286
uniprot id: G3WTD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100928631
gene id: 9305:LOC100928631
uniprot id: G3VV08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:SAR1B
gene id: 9305:SAR1B
uniprot id: G3WQF3
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

9305:LMF1
gene id: 9305:LMF1
uniprot id: G3WR27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

9305:VRK1
gene id: 9305:VRK1
uniprot id: A0A7N4NZV3
uniprot id: G3WJQ2
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:LOC100934853
gene id: 9305:LOC100934853
uniprot id: G3VXV3
names: Subcellular Location Annotation
messages: Membrane

9305:BMP5
gene id: 9305:BMP5
uniprot id: G3W5W3
names: Similarity
messages: Belongs to the TGF-beta family.

9305:LOC100913370
gene id: 9305:LOC100913370
uniprot id: G3VSX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ATP8B4
gene id: 9305:ATP8B4
uniprot id: A0A7N4NIQ7
uniprot id: G3VZD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9305:LOC100917327
gene id: 9305:LOC100917327
uniprot id: G3WM20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9305:LOC100927692
gene id: 9305:LOC100927692
uniprot id: G3VTY4
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

9305:SNCG
gene id: 9305:SNCG
uniprot id: G3VPA3
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.

9305:URGCP
gene id: 9305:URGCP
uniprot id: A0A7N4PXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

9305:CTSC
gene id: 9305:CTSC
uniprot id: A0A7N4PWD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Lysosome
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

9305:GAP43
gene id: 9305:GAP43
uniprot id: G3W8Q7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neuromodulin family.
messages: Cell membrane
messages: Cytoplasm
messages: Identified in a complex containing FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43 and CTTN. Interacts (via IQ domain) with calmodulin. Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
messages: Membrane
messages: Palmitoylated. Palmitoylation is essential for plasma membrane association.
messages: Perikaryon
messages: Synapse
messages: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
messages: axon
messages: dendrite
messages: filopodium membrane
messages: growth cone membrane

9305:RPL13
gene id: 9305:RPL13
uniprot id: A0A7N4NY33
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

9305:GJB1
gene id: 9305:GJB1
uniprot id: G3W9X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9305:LOC100932757
gene id: 9305:LOC100932757
uniprot id: A0A7N4NWH5
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100921853
gene id: 9305:LOC100921853
uniprot id: A0A7N4V624
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TAF15
gene id: 9305:TAF15
uniprot id: G3VK30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

9305:LOC100932290
gene id: 9305:LOC100932290
uniprot id: G3WNJ3
names: Similarity
messages: Belongs to the intermediate filament family.

9305:ADGRG5
gene id: 9305:ADGRG5
uniprot id: A0A7N4UXB8
uniprot id: G3VMD6
uniprot id: G3VMD7
names: Subcellular Location Annotation
messages: Membrane

9305:GJA8
gene id: 9305:GJA8
uniprot id: G3X210
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9305:GPR137
gene id: 9305:GPR137
uniprot id: G3VSP2
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

9305:AMPD1
gene id: 9305:AMPD1
uniprot id: A0A7N4PYR3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

9305:SLC4A1
gene id: 9305:SLC4A1
uniprot id: G3WSG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine.
messages: Membrane

9305:PSMG2
gene id: 9305:PSMG2
uniprot id: A0A7N4V3P4
uniprot id: G3W9D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

9305:BPNT1
gene id: 9305:BPNT1
uniprot id: G3VN28
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9305:LSM2
gene id: 9305:LSM2
uniprot id: A0A7N4PCU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

9305:TLR5
gene id: 9305:TLR5
uniprot id: A0A7N4PYE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9305:LOC100926334
gene id: 9305:LOC100926334
uniprot id: A0A7N4NIT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:NUP58
gene id: 9305:NUP58
uniprot id: A0A7N4NTK8
names: Subcellular Location Annotation
messages: nuclear pore complex

9305:SEC11C
gene id: 9305:SEC11C
uniprot id: A0A7N4V224
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:LOC100921928
gene id: 9305:LOC100921928
uniprot id: G3WMV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9305:XRCC4
gene id: 9305:XRCC4
uniprot id: G3W756
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

9305:NCAPH
gene id: 9305:NCAPH
uniprot id: G3X235
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

9305:NUSAP1
gene id: 9305:NUSAP1
uniprot id: G3WWX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

9305:FGF11
gene id: 9305:FGF11
uniprot id: A0A7N4NY15
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9305:GPR68
gene id: 9305:GPR68
uniprot id: A0A7N4V760
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:LRP3
gene id: 9305:LRP3
uniprot id: G3WSE7
uniprot id: G3WSE8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:PMVK
gene id: 9305:PMVK
uniprot id: G3VJZ4
names: Subcellular Location Annotation
messages: cytosol

9305:SH3RF2
gene id: 9305:SH3RF2
uniprot id: G3VGM7
names: Similarity
messages: Belongs to the SH3RF family.

9305:ND1
gene id: 9305:ND1
uniprot id: G1FKB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

9305:GUCA2A
gene id: 9305:GUCA2A
uniprot id: A0A7N4PU88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

9305:CACFD1
gene id: 9305:CACFD1
uniprot id: A0A7N4P7V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

9305:NDUFAF1
gene id: 9305:NDUFAF1
uniprot id: A0A7N4P8M3
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

9305:LOC100934536
gene id: 9305:LOC100934536
uniprot id: A0A7N4PP91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:YIPF2
gene id: 9305:YIPF2
uniprot id: A0A7N4V214
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

9305:PLD4
gene id: 9305:PLD4
uniprot id: G3VUX0
names: Similarity
messages: Belongs to the phospholipase D family.

9305:LOC100927853
gene id: 9305:LOC100927853
uniprot id: A0A7N4PMY5
names: Subcellular Location Annotation
messages: Membrane

9305:TACC3
gene id: 9305:TACC3
uniprot id: G3WKQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

9305:LOC100926452
gene id: 9305:LOC100926452
uniprot id: G3VU44
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9305:ORC2
gene id: 9305:ORC2
uniprot id: G3WHS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

9305:LOC100916628
gene id: 9305:LOC100916628
uniprot id: G3WK57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:NKIRAS2
gene id: 9305:NKIRAS2
uniprot id: A0A7N4V317
uniprot id: G3VZ86
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

9305:CAB39L
gene id: 9305:CAB39L
uniprot id: A0A7N4P5F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

9305:LMOD3
gene id: 9305:LMOD3
uniprot id: G3WVM1
names: Subcellular Location Annotation
messages: cytoskeleton

9305:LOC100925541
gene id: 9305:LOC100925541
uniprot id: A0A7N4V170
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

9305:RPL19
gene id: 9305:RPL19
uniprot id: G3WVF4
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

9305:LOC100915180
gene id: 9305:LOC100915180
uniprot id: G3WUB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9305:NOTUM
gene id: 9305:NOTUM
uniprot id: A0A7N4NI26
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

9305:NT5C2
gene id: 9305:NT5C2
uniprot id: A0A7N4PI82
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

9305:ENPP2
gene id: 9305:ENPP2
uniprot id: A0A7N4NS23
uniprot id: G3WYS1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Secreted

9305:PLPPR4
gene id: 9305:PLPPR4
uniprot id: G3WCP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9305:POLG
gene id: 9305:POLG
uniprot id: G3WRQ4
names: Function
names: Subcellular Location Annotation
messages: Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
messages: mitochondrion nucleoid

9305:MSRB2
gene id: 9305:MSRB2
uniprot id: G3VY02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

9305:KCNMB1
gene id: 9305:KCNMB1
uniprot id: G3X3H5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

9305:ACSS2
gene id: 9305:ACSS2
uniprot id: A0A7N4P524
uniprot id: G3X0M2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9305:PSMA7
gene id: 9305:PSMA7
uniprot id: A0A7N4P7S8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9305:LDHB
gene id: 9305:LDHB
uniprot id: G3WRT3
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

9305:PRORP
gene id: 9305:PRORP
uniprot id: A0A7N4PPR7
names: Similarity
messages: Belongs to the PPR family. P subfamily.

9305:CIAO3
gene id: 9305:CIAO3
uniprot id: G3WEQ3
names: Similarity
messages: Belongs to the NARF family.

9305:ATM
gene id: 9305:ATM
uniprot id: G3WB56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Cytoplasmic vesicle
messages: Nucleus
messages: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9, UBQLN4 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response. Phosphorylates ERCC6 which is essential for its chromatin remodeling activity at DNA double-strand breaks.

9305:LOC100928604
gene id: 9305:LOC100928604
uniprot id: G3VBY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:NLGN4X
gene id: 9305:NLGN4X
uniprot id: A0A7N4PS39
uniprot id: G3VQX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

9305:QTRT2
gene id: 9305:QTRT2
uniprot id: A0A7N4PM82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

9305:TLR6
gene id: 9305:TLR6
uniprot id: G3W9V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9305:HSP90B1
gene id: 9305:HSP90B1
uniprot id: A0A7N4PIG4
uniprot id: G3VE83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

9305:MYADML2
gene id: 9305:MYADML2
uniprot id: A0A7N4PVE6
names: Subcellular Location Annotation
messages: Membrane

9305:F10
gene id: 9305:F10
uniprot id: G3WXN7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:ISCA1
gene id: 9305:ISCA1
uniprot id: A0A7N4PA31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

9305:ORC6
gene id: 9305:ORC6
uniprot id: A0A7N4PXC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

9305:PKM
gene id: 9305:PKM
uniprot id: A0A7N4V2Q6
names: Similarity
messages: Belongs to the pyruvate kinase family.

9305:CAVIN4
gene id: 9305:CAVIN4
uniprot id: A0A7N4NFW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola
messages: sarcomere

9305:PLCG2
gene id: 9305:PLCG2
uniprot id: G3WDW2
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

9305:XIAP
gene id: 9305:XIAP
uniprot id: G3WUX1
names: Similarity
messages: Belongs to the IAP family.

9305:CUTA
gene id: 9305:CUTA
uniprot id: G3VH61
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

9305:LOC100923721
gene id: 9305:LOC100923721
uniprot id: G3WCG3
uniprot id: G3WCQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:DYRK2
gene id: 9305:DYRK2
uniprot id: A0A7N4P6R6
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

9305:AP1M2
gene id: 9305:AP1M2
uniprot id: G3VRS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

9305:JPH3
gene id: 9305:JPH3
uniprot id: G3WYM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

9305:RPS21
gene id: 9305:RPS21
uniprot id: A0A7N4NNE8
uniprot id: G3WKL3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

9305:SLC9A3R2
gene id: 9305:SLC9A3R2
uniprot id: A0A7N4P3T1
names: Function
names: Subcellular Location Annotation
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

9305:PMPCA
gene id: 9305:PMPCA
uniprot id: G3VZ76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix
messages: Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.

9305:FAM124B
gene id: 9305:FAM124B
uniprot id: G3VQJ4
names: Similarity
messages: Belongs to the FAM124 family.

9305:KMO
gene id: 9305:KMO
uniprot id: G3WFS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
messages: Mitochondrion outer membrane

9305:CCDC58
gene id: 9305:CCDC58
uniprot id: G3WKT9
names: Similarity
messages: Belongs to the MIX23 family.

9305:SNX21
gene id: 9305:SNX21
uniprot id: A0A7N4PBL4
uniprot id: G3VFN3
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

9305:CHGA
gene id: 9305:CHGA
uniprot id: G3WCF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

9305:RXRB
gene id: 9305:RXRB
uniprot id: G3VV01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

9305:KCNA6
gene id: 9305:KCNA6
uniprot id: A0A7N4V2T3
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100931085
gene id: 9305:LOC100931085
uniprot id: A0A7N4PUA2
names: Subcellular Location Annotation
messages: Membrane

9305:HBEGF
gene id: 9305:HBEGF
uniprot id: A0A7N4NV65
uniprot id: G3WT08
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:MFAP1
gene id: 9305:MFAP1
uniprot id: G3WP54
names: Function
names: Similarity
messages: Belongs to the MFAP1 family.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.

9305:TAS2R38
gene id: 9305:TAS2R38
uniprot id: G3VUK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9305:LOC100920270
gene id: 9305:LOC100920270
uniprot id: G3WBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

9305:SGO2
gene id: 9305:SGO2
uniprot id: A0A7N4Q0K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

9305:ALKAL2
gene id: 9305:ALKAL2
uniprot id: G3VQN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

9305:IST1
gene id: 9305:IST1
uniprot id: A0A7N4NWC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

9305:ZDHHC23
gene id: 9305:ZDHHC23
uniprot id: A0A7N4PIJ7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9305:LOC100914350
gene id: 9305:LOC100914350
uniprot id: G3VGR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:VGLL4
gene id: 9305:VGLL4
uniprot id: G3X343
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

9305:LOC100913506
gene id: 9305:LOC100913506
uniprot id: A0A7N4V739
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:HBM
gene id: 9305:HBM
uniprot id: A0A7N4PYH5
names: Similarity
messages: Belongs to the globin family.

9305:TPD52L2
gene id: 9305:TPD52L2
uniprot id: A0A7N4NYG9
uniprot id: A0A7N4PXN4
uniprot id: G3WYD3
names: Similarity
messages: Belongs to the TPD52 family.

9305:GREM1
gene id: 9305:GREM1
uniprot id: A0A7N4Q0B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

9305:LOC100923904
gene id: 9305:LOC100923904
uniprot id: G3WGM3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9305:NHP2
gene id: 9305:NHP2
uniprot id: A0A7N4NYC1
uniprot id: G3WSF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

9305:USP15
gene id: 9305:USP15
uniprot id: G3WIA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

9305:DLD
gene id: 9305:DLD
uniprot id: G3VMS5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

9305:LOC100913525
gene id: 9305:LOC100913525
uniprot id: A0A7N4PLP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

9305:POPDC2
gene id: 9305:POPDC2
uniprot id: A0A7N4P4C4
names: Similarity
messages: Belongs to the popeye family.

9305:NSUN7
gene id: 9305:NSUN7
uniprot id: G3WY64
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:ALAD
gene id: 9305:ALAD
uniprot id: A0A7N4PY89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer; active form. Homohexamer; low activity form.

9305:MED23
gene id: 9305:MED23
uniprot id: A0A7N4P785
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 23 family.
messages: Nucleus

9305:C3H11orf54
gene id: 9305:C3H11orf54
uniprot id: G3VST9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

9305:SPTAN1
gene id: 9305:SPTAN1
uniprot id: G3X3E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

9305:MMD
gene id: 9305:MMD
uniprot id: A0A7N4V2L4
uniprot id: G3WQJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9305:LOC100932786
gene id: 9305:LOC100932786
uniprot id: G3WJU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

9305:DUSP6
gene id: 9305:DUSP6
uniprot id: G3VNF8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9305:GOLT1A
gene id: 9305:GOLT1A
uniprot id: G3VFL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

9305:HNF1B
gene id: 9305:HNF1B
uniprot id: G3VRI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

9305:WARS1
gene id: 9305:WARS1
uniprot id: G3WLE5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9305:TLR10
gene id: 9305:TLR10
uniprot id: G3WAH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9305:LAGE3
gene id: 9305:LAGE3
uniprot id: A0A7N4PMU0
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

9305:GJB5
gene id: 9305:GJB5
uniprot id: A0A7N4NQE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9305:SLC45A1
gene id: 9305:SLC45A1
uniprot id: G3WCA1
names: Subcellular Location Annotation
messages: Membrane

9305:VOPP1
gene id: 9305:VOPP1
uniprot id: A0A7N4UXD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.
messages: Membrane

9305:ITPRIP
gene id: 9305:ITPRIP
uniprot id: A0A7N4NUY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Cell membrane
messages: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.
messages: Membrane
messages: Nucleus outer membrane

9305:ALDH1B1
gene id: 9305:ALDH1B1
uniprot id: G3WMK0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9305:TSEN2
gene id: 9305:TSEN2
uniprot id: A0A7N4NWR9
uniprot id: G3WA36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

9305:PGM3
gene id: 9305:PGM3
uniprot id: G3WU51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

9305:KRT36
gene id: 9305:KRT36
uniprot id: G3VPL3
names: Similarity
messages: Belongs to the intermediate filament family.

9305:LOC100929313
gene id: 9305:LOC100929313
uniprot id: G3VK96
uniprot id: G3VNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:DEUP1
gene id: 9305:DEUP1
uniprot id: G3VZA6
uniprot id: G3VZA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP63 family.
messages: Cytoplasm

9305:LOC100924633
gene id: 9305:LOC100924633
uniprot id: A0A7N4P8P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:NUMB
gene id: 9305:NUMB
uniprot id: A0A7N4P5X1
uniprot id: A0A7N4PW51
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Plays a role in the process of neurogenesis.

9305:LOC100918626
gene id: 9305:LOC100918626
uniprot id: G3WK84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9305:PENK
gene id: 9305:PENK
uniprot id: A0A7N4PCL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Neuropeptide that competes with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Secreted
messages: chromaffin granule lumen

9305:METRNL
gene id: 9305:METRNL
uniprot id: G3VCQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the meteorin family.
messages: Secreted

9305:TIPIN
gene id: 9305:TIPIN
uniprot id: G3WCJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

9305:THUMPD3
gene id: 9305:THUMPD3
uniprot id: G3WNL4
names: Similarity
messages: Belongs to the methyltransferase superfamily.

9305:RIC8B
gene id: 9305:RIC8B
uniprot id: G3WKC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

9305:P2RY2
gene id: 9305:P2RY2
uniprot id: A0A7N4NSV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LARP7
gene id: 9305:LARP7
uniprot id: G3W1W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LARP7 family.
messages: nucleoplasm

9305:COPZ1
gene id: 9305:COPZ1
uniprot id: A0A7N4NJF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

9305:LOC100925121
gene id: 9305:LOC100925121
uniprot id: A0A7N4PWE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PTPN21
gene id: 9305:PTPN21
uniprot id: A0A7N4V1S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

9305:LOC100922782
gene id: 9305:LOC100922782
uniprot id: G3VRX2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

9305:BANF2
gene id: 9305:BANF2
uniprot id: A0A7N4NR52
names: Subcellular Location Annotation
messages: Nucleus

9305:STAC3
gene id: 9305:STAC3
uniprot id: G3VKM5
names: Subcellular Location Annotation
messages: sarcolemma

9305:LOC100916112
gene id: 9305:LOC100916112
uniprot id: A0A7N4NH48
uniprot id: A0A7N4PYM7
uniprot id: A0A7N4UZV4
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

9305:OSBPL2
gene id: 9305:OSBPL2
uniprot id: A0A7N4P768
uniprot id: A0A7N4P8T3
names: Similarity
messages: Belongs to the OSBP family.

9305:DRC1
gene id: 9305:DRC1
uniprot id: G3VJS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DRC1 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: cilium axoneme
messages: flagellum axoneme

9305:LOC100913210
gene id: 9305:LOC100913210
uniprot id: G3VM57
names: Similarity
messages: Belongs to the PRORSD1 family.

9305:LOC100916813
gene id: 9305:LOC100916813
uniprot id: A0A7N4NHT5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:ALG8
gene id: 9305:ALG8
uniprot id: A0A7N4Q0D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:GNB2
gene id: 9305:GNB2
uniprot id: G3W3Y2
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

9305:LOC100920038
gene id: 9305:LOC100920038
uniprot id: G3VMS6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9305:LOC100928798
gene id: 9305:LOC100928798
uniprot id: G3WDG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:GIPC2
gene id: 9305:GIPC2
uniprot id: A0A7N4V825
names: Similarity
messages: Belongs to the GIPC family.

9305:FTCD
gene id: 9305:FTCD
uniprot id: G3VL73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds and promotes bundling of vimentin filaments originating from the Golgi.
messages: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
messages: Golgi apparatus
messages: Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.
messages: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
messages: In the N-terminal section; belongs to the formiminotransferase family.
messages: centriole

9305:LOC100924358
gene id: 9305:LOC100924358
uniprot id: A0A7N4V0K0
uniprot id: G3VEI0
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9305:NDUFA2
gene id: 9305:NDUFA2
uniprot id: A0A7N4PNZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9305:GAS6
gene id: 9305:GAS6
uniprot id: G3WMN3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:POPDC3
gene id: 9305:POPDC3
uniprot id: G3WKA6
names: Similarity
messages: Belongs to the popeye family.

9305:IRF2
gene id: 9305:IRF2
uniprot id: A0A7N4PMA3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9305:RAB27A
gene id: 9305:RAB27A
uniprot id: A0A7N4NQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

9305:LOC100924186
gene id: 9305:LOC100924186
uniprot id: G3VC53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:GABRA6
gene id: 9305:GABRA6
uniprot id: G3VQ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9305:AVPR1B
gene id: 9305:AVPR1B
uniprot id: G3WX95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

9305:FGF22
gene id: 9305:FGF22
uniprot id: A0A7N4PBF5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9305:OPRK1
gene id: 9305:OPRK1
uniprot id: A0A7N4PNW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with SLC9A3R1. Interacts with GABARAPL1.
messages: Membrane

9305:UCKL1
gene id: 9305:UCKL1
uniprot id: G3WXS6
names: Similarity
messages: Belongs to the uridine kinase family.

9305:IL4R
gene id: 9305:IL4R
uniprot id: A0A7N4PYF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Membrane
messages: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

9305:STXBP1
gene id: 9305:STXBP1
uniprot id: G3X0W3
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

9305:LOC100923217
gene id: 9305:LOC100923217
uniprot id: A0A7N4UZL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LMOD1
gene id: 9305:LMOD1
uniprot id: G3WB36
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

9305:LOC100920407
gene id: 9305:LOC100920407
uniprot id: A0A7N4PUM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ITGB3BP
gene id: 9305:ITGB3BP
uniprot id: A0A7N4PDY8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription coregulator that can have both coactivator and corepressor functions.
messages: centromere
messages: kinetochore

9305:SLC6A12
gene id: 9305:SLC6A12
uniprot id: A0A7N4NMI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
messages: Interacts with LIN7C.
messages: Membrane
messages: Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.

9305:DGAT2
gene id: 9305:DGAT2
uniprot id: A0A7N4PDV3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:KLC4
gene id: 9305:KLC4
uniprot id: G3WFJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

9305:LOC100935036
gene id: 9305:LOC100935036
uniprot id: G3WPU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:GPRC5D
gene id: 9305:GPRC5D
uniprot id: G3W940
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:GNL2
gene id: 9305:GNL2
uniprot id: G3WG05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

9305:MYMK
gene id: 9305:MYMK
uniprot id: G3VZY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

9305:LOC100924997
gene id: 9305:LOC100924997
uniprot id: G3WDE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:SLC7A7
gene id: 9305:SLC7A7
uniprot id: G3WFV1
names: Subcellular Location Annotation
messages: Membrane

9305:MAEA
gene id: 9305:MAEA
uniprot id: A0A7N4NTW4
uniprot id: A0A7N4V611
names: Subcellular Location Annotation
messages: Nucleus matrix

9305:HSP90AB1
gene id: 9305:HSP90AB1
uniprot id: G3WYP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

9305:RRP12
gene id: 9305:RRP12
uniprot id: G3X1M2
names: Similarity
messages: Belongs to the RRP12 family.

9305:ATP23
gene id: 9305:ATP23
uniprot id: G3WBB2
names: Similarity
messages: Belongs to the peptidase M76 family.

9305:HBS1L
gene id: 9305:HBS1L
uniprot id: G3WKA1
names: Subunit
messages: Interacts with the SKI complex.

9305:LOC100923021
gene id: 9305:LOC100923021
uniprot id: A0A7N4V0P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ADGRG3
gene id: 9305:ADGRG3
uniprot id: G3VVG0
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100921186
gene id: 9305:LOC100921186
uniprot id: A0A7N4NGE8
uniprot id: G3W3X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

9305:DDX24
gene id: 9305:DDX24
uniprot id: G3W4Z2
names: Similarity
messages: Belongs to the DEAD box helicase family.

9305:CCT4
gene id: 9305:CCT4
uniprot id: G3W3A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

9305:SOX9
gene id: 9305:SOX9
uniprot id: A0A7N4UX98
names: Subcellular Location Annotation
messages: Nucleus

9305:DYNC1LI2
gene id: 9305:DYNC1LI2
uniprot id: G3VN53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

9305:HS6ST1
gene id: 9305:HS6ST1
uniprot id: G3WKD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

9305:APOA4
gene id: 9305:APOA4
uniprot id: G3WJL0
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

9305:PCSK2
gene id: 9305:PCSK2
uniprot id: G3W9J3
names: Similarity
messages: Belongs to the peptidase S8 family.

9305:RIOK3
gene id: 9305:RIOK3
uniprot id: G3WEK7
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
messages: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.

9305:DUS4L
gene id: 9305:DUS4L
uniprot id: G3WHV9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

9305:CDK10
gene id: 9305:CDK10
uniprot id: A0A7N4PRD3
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:ADAMTS4
gene id: 9305:ADAMTS4
uniprot id: A0A7N4PLK6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9305:LOC100933860
gene id: 9305:LOC100933860
uniprot id: G3WVN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PRDM8
gene id: 9305:PRDM8
uniprot id: A0A7N4NHN1
names: Subcellular Location Annotation
messages: Nucleus

9305:AKR1D1
gene id: 9305:AKR1D1
uniprot id: G3VPF6
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9305:LOC100932392
gene id: 9305:LOC100932392
uniprot id: A0A7N4PTC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:CCDC103
gene id: 9305:CCDC103
uniprot id: G3W332
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC103/PR46b family.
messages: Cytoplasm
messages: Dynein-attachment factor required for cilia motility.
messages: Homodimer.
messages: flagellum

9305:LOC100932534
gene id: 9305:LOC100932534
uniprot id: A0A7N4PB86
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:DGKE
gene id: 9305:DGKE
uniprot id: G3VEH5
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9305:ETS2
gene id: 9305:ETS2
uniprot id: G3VY84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcription factor.

9305:LOC100918963
gene id: 9305:LOC100918963
uniprot id: G3WSP3
names: Subcellular Location Annotation
messages: Cytoplasm

9305:KCNA5
gene id: 9305:KCNA5
uniprot id: G3WDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.
messages: Cell membrane
messages: Membrane

9305:ACOT13
gene id: 9305:ACOT13
uniprot id: A0A7N4PTR7
names: Similarity
messages: Belongs to the thioesterase PaaI family.

9305:KRT19
gene id: 9305:KRT19
uniprot id: G3VKB3
names: Similarity
messages: Belongs to the intermediate filament family.

9305:NAA10
gene id: 9305:NAA10
uniprot id: A0A7N4PR93
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

9305:ST8SIA5
gene id: 9305:ST8SIA5
uniprot id: A0A7N4NLV6
uniprot id: A0A7N4PQ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9305:P4HB
gene id: 9305:P4HB
uniprot id: A0A7N4V284
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

9305:HOXB8
gene id: 9305:HOXB8
uniprot id: A0A7N4UY57
names: Subcellular Location Annotation
messages: Nucleus

9305:COPE
gene id: 9305:COPE
uniprot id: A0A7N4PVN0
uniprot id: G3WB38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

9305:LOC100930308
gene id: 9305:LOC100930308
uniprot id: G3X1Z9
names: Similarity
messages: Belongs to the CBP3 family.

9305:GRP
gene id: 9305:GRP
uniprot id: G3WHY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Induces an itch response through activation of receptors present on mast cells, triggering mast cell degranulation.
messages: Secreted
messages: neuron projection
messages: secretory vesicle lumen

9305:SLC52A3
gene id: 9305:SLC52A3
uniprot id: G3W5B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

9305:HOXB7
gene id: 9305:HOXB7
uniprot id: A0A7N4PE53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9305:LOC100920534
gene id: 9305:LOC100920534
uniprot id: A0A7N4NHN7
uniprot id: G3VLX0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:NT5C3B
gene id: 9305:NT5C3B
uniprot id: A0A7N4PXB1
uniprot id: G3VGG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

9305:IPO4
gene id: 9305:IPO4
uniprot id: A0A7N4P330
names: Subcellular Location Annotation
messages: Cytoplasm

9305:METTL14
gene id: 9305:METTL14
uniprot id: G3WMS9
names: Similarity
messages: Belongs to the MT-A70-like family.

9305:CDKAL1
gene id: 9305:CDKAL1
uniprot id: G3WJ31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

9305:FECH
gene id: 9305:FECH
uniprot id: G3X087
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

9305:LOC100925856
gene id: 9305:LOC100925856
uniprot id: G3VS69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:DDIT4L
gene id: 9305:DDIT4L
uniprot id: A0A7N4NUX7
names: Similarity
messages: Belongs to the DDIT4 family.

9305:ATL3
gene id: 9305:ATL3
uniprot id: G3VGY7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9305:NFYB
gene id: 9305:NFYB
uniprot id: A0A7N4V586
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
messages: Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding. Interacts with C1QBP.

9305:AQP5
gene id: 9305:AQP5
uniprot id: G3VMA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

9305:CHD8
gene id: 9305:CHD8
uniprot id: A0A7N4PRE4
uniprot id: G3W1S9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. CHD8 subfamily.
messages: DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. Involved in both enhancer blocking and epigenetic remodeling at chromatin boundary via its interaction with CTCF. Acts as a suppressor of STAT3 activity by suppressing the LIF-induced STAT3 transcriptional activity. Also acts as a transcription activator via its interaction with ZNF143 by participating in efficient U6 RNA polymerase III transcription.
messages: Interacts with p53/TP53, histone H1, CTNNB1, CTCF and PIAS3. Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Interacts with CHD7. Interacts with FAM124B.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Sumoylated.

9305:AFP
gene id: 9305:AFP
uniprot id: G3WQV0
names: Subcellular Location Annotation
messages: Secreted

9305:OSTC
gene id: 9305:OSTC
uniprot id: G3W2G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1.

9305:BCAS2
gene id: 9305:BCAS2
uniprot id: G3W2X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

9305:ALOX12B
gene id: 9305:ALOX12B
uniprot id: G3WKY8
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:TNR
gene id: 9305:TNR
uniprot id: A0A7N4NX58
uniprot id: G3WNL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

9305:GPCPD1
gene id: 9305:GPCPD1
uniprot id: A0A7N4PUA5
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

9305:LOC100933728
gene id: 9305:LOC100933728
uniprot id: G3VD24
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9305:TANGO6
gene id: 9305:TANGO6
uniprot id: G3WCW1
names: Similarity
messages: Belongs to the Tango6 family.

9305:FMOD
gene id: 9305:FMOD
uniprot id: G3WXK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to type I and type II collagen.
messages: extracellular matrix

9305:FAM133B
gene id: 9305:FAM133B
uniprot id: A0A7N4P5U1
names: Similarity
messages: Belongs to the FAM133 family.

9305:CFB
gene id: 9305:CFB
uniprot id: G3W3U6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:PPIH
gene id: 9305:PPIH
uniprot id: G3WLS4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9305:SDHAF4
gene id: 9305:SDHAF4
uniprot id: A0A7N4P832
names: Similarity
messages: Belongs to the SDHAF4 family.

9305:SARAF
gene id: 9305:SARAF
uniprot id: G3WF88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Interacts with STIM1; the interaction is inhibit by th interaction of STIM1 with EFHB.
messages: Membrane
messages: Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.

9305:ENTPD8
gene id: 9305:ENTPD8
uniprot id: G3WE81
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9305:TTC36
gene id: 9305:TTC36
uniprot id: G3WH04
names: Similarity
messages: Belongs to the TTC36 family.

9305:LOC100914861
gene id: 9305:LOC100914861
uniprot id: A0A7N4PBC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MVD
gene id: 9305:MVD
uniprot id: G3VUM6
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

9305:DYNC2LI1
gene id: 9305:DYNC2LI1
uniprot id: A0A7N4PHU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

9305:EMC2
gene id: 9305:EMC2
uniprot id: G3WMK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

9305:AFF1
gene id: 9305:AFF1
uniprot id: G3VNN4
uniprot id: G3VNN5
names: Similarity
messages: Belongs to the AF4 family.

9305:TMEM98
gene id: 9305:TMEM98
uniprot id: G3X0F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

9305:PTAR1
gene id: 9305:PTAR1
uniprot id: G3VRK5
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

9305:DAXX
gene id: 9305:DAXX
uniprot id: A0A7N4P8S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAXX family.
messages: Cytoplasm
messages: PML body
messages: centromere
messages: nucleolus
messages: nucleoplasm

9305:LOC100933712
gene id: 9305:LOC100933712
uniprot id: A0A7N4V7B5
uniprot id: G3VVW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

9305:LOC100926163
gene id: 9305:LOC100926163
uniprot id: G3WLB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9305:TSHR
gene id: 9305:TSHR
uniprot id: G3VPN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

9305:LHX2
gene id: 9305:LHX2
uniprot id: A0A7N4PXC3
uniprot id: G3WQE4
names: Subcellular Location Annotation
messages: Nucleus

9305:HSD17B4
gene id: 9305:HSD17B4
uniprot id: G3VS44
names: Subcellular Location Annotation
messages: Peroxisome

9305:LOC100923912
gene id: 9305:LOC100923912
uniprot id: A0A7N4V105
uniprot id: G3VKN4
names: Subcellular Location Annotation
messages: Membrane

9305:RRP15
gene id: 9305:RRP15
uniprot id: G3WYZ1
names: Similarity
messages: Belongs to the RRP15 family.

9305:PAPPA
gene id: 9305:PAPPA
uniprot id: G3WAX2
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LGMN
gene id: 9305:LGMN
uniprot id: G3W763
names: Similarity
messages: Belongs to the peptidase C13 family.

9305:SIRT3
gene id: 9305:SIRT3
uniprot id: G3W512
names: Cofactor
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.

9305:SYT2
gene id: 9305:SYT2
uniprot id: G3WNY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

9305:FSHR
gene id: 9305:FSHR
uniprot id: G3WGP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
messages: Membrane

9305:WASHC5
gene id: 9305:WASHC5
uniprot id: G3VVD7
uniprot id: G3VVD8
names: Similarity
messages: Belongs to the strumpellin family.

9305:SMOC1
gene id: 9305:SMOC1
uniprot id: G3X3H7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100922880
gene id: 9305:LOC100922880
uniprot id: G3WU75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Membrane

9305:VIRMA
gene id: 9305:VIRMA
uniprot id: G3WY88
names: Similarity
messages: Belongs to the vir family.

9305:PREPL
gene id: 9305:PREPL
uniprot id: A0A7N4UZ79
uniprot id: G3X244
names: Similarity
messages: Belongs to the peptidase S9A family.

9305:HTR3A
gene id: 9305:HTR3A
uniprot id: A0A7N4V7H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

9305:MTM1
gene id: 9305:MTM1
uniprot id: A0A7N4P9Q0
uniprot id: G3WVR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cell membrane
messages: Late endosome
messages: filopodium
messages: ruffle
messages: sarcomere

9305:APOC2
gene id: 9305:APOC2
uniprot id: A0A7N4PCI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C2 family.
messages: Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.
messages: Secreted

9305:ACTBL2
gene id: 9305:ACTBL2
uniprot id: G3W5K4
names: Similarity
messages: Belongs to the actin family.

9305:HS6ST2
gene id: 9305:HS6ST2
uniprot id: A0A7N4NYG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

9305:POLR2B
gene id: 9305:POLR2B
uniprot id: G3WU38
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

9305:ELAVL2
gene id: 9305:ELAVL2
uniprot id: A0A7N4NM96
names: Similarity
messages: Belongs to the RRM elav family.

9305:NDE1
gene id: 9305:NDE1
uniprot id: G3W2T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: kinetochore
messages: spindle

9305:LOC100917307
gene id: 9305:LOC100917307
uniprot id: G3WH33
names: Subcellular Location Annotation
messages: Nucleus

9305:CDKN2AIP
gene id: 9305:CDKN2AIP
uniprot id: A0A7N4NXM3
names: Similarity
messages: Belongs to the CARF family.

9305:CDO1
gene id: 9305:CDO1
uniprot id: A0A7N4PFC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

9305:MFAP5
gene id: 9305:MFAP5
uniprot id: A0A7N4PS60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

9305:UCN3
gene id: 9305:UCN3
uniprot id: G3VGX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

9305:GRK1
gene id: 9305:GRK1
uniprot id: G3WQG6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

9305:LOC100930813
gene id: 9305:LOC100930813
uniprot id: A0A7N4NKY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:DSCC1
gene id: 9305:DSCC1
uniprot id: G3X094
names: Similarity
messages: Belongs to the DCC1 family.

9305:LOC100927726
gene id: 9305:LOC100927726
uniprot id: G3W2M7
names: Similarity
messages: Belongs to the Speedy/Ringo family.

9305:KCNK15
gene id: 9305:KCNK15
uniprot id: A0A7N4UYS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9305:BRD1
gene id: 9305:BRD1
uniprot id: G3WWF4
names: Subcellular Location Annotation
messages: Nucleus

9305:EIPR1
gene id: 9305:EIPR1
uniprot id: G3WNG2
names: Similarity
messages: Belongs to the WD repeat EIPR1 family.

9305:LOC100915895
gene id: 9305:LOC100915895
uniprot id: G3VIZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum
messages: perinuclear region

9305:LOC100933586
gene id: 9305:LOC100933586
uniprot id: G3VZT4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

9305:SLC7A14
gene id: 9305:SLC7A14
uniprot id: G3WN39
names: Subcellular Location Annotation
messages: Membrane

9305:BACE1
gene id: 9305:BACE1
uniprot id: G3WAG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

9305:LOC116419008
gene id: 9305:LOC116419008
uniprot id: A0A7N4NTK1
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:SENP3
gene id: 9305:SENP3
uniprot id: G3WT25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

9305:GLDC
gene id: 9305:GLDC
uniprot id: G3VSM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

9305:LPCAT2
gene id: 9305:LPCAT2
uniprot id: A0A7N4PQH0
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9305:SERPINB10
gene id: 9305:SERPINB10
uniprot id: A0A7N4PYX0
names: Similarity
messages: Belongs to the serpin family.

9305:LOC100921730
gene id: 9305:LOC100921730
uniprot id: A0A7N4Q2D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PSMB3
gene id: 9305:PSMB3
uniprot id: A0A7N4PTH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9305:SLC22A2
gene id: 9305:SLC22A2
uniprot id: A0A7N4PDE0
uniprot id: G3WUZ0
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

9305:SLC9A2
gene id: 9305:SLC9A2
uniprot id: G3VXQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Interacts with CHP1 and CHP2.
messages: Membrane

9305:LALBA
gene id: 9305:LALBA
uniprot id: G3VEF8
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.

9305:CASP3
gene id: 9305:CASP3
uniprot id: A0A7N4NMK7
uniprot id: G3W5D0
names: Similarity
messages: Belongs to the peptidase C14A family.

9305:DMAC2L
gene id: 9305:DMAC2L
uniprot id: A0A7N4PZJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP synthase subunit s family.
messages: Homotetramer. Associates with ATP synthase.
messages: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
messages: Membrane
messages: Mitochondrion inner membrane

9305:LOC100926824
gene id: 9305:LOC100926824
uniprot id: A0A7N4NRC6
names: Subcellular Location Annotation
messages: Membrane

9305:LOC105750535
gene id: 9305:LOC105750535
uniprot id: G3WLP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9305:LOC100917086
gene id: 9305:LOC100917086
uniprot id: G3WEL2
uniprot id: G3WFE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

9305:ATXN3
gene id: 9305:ATXN3
uniprot id: A0A7N4PMS7
uniprot id: G3W8T7
names: Subcellular Location Annotation
messages: Nucleus

9305:LOC100922468
gene id: 9305:LOC100922468
uniprot id: G3VBS4
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:LOC100922751
gene id: 9305:LOC100922751
uniprot id: A0A7N4PEP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:FICD
gene id: 9305:FICD
uniprot id: A0A7N4PSS5
names: Similarity
messages: Belongs to the fic family.

9305:GADD45G
gene id: 9305:GADD45G
uniprot id: G3VNU9
names: Similarity
messages: Belongs to the GADD45 family.

9305:LSM4
gene id: 9305:LSM4
uniprot id: A0A7N4UYF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

9305:SNAP23
gene id: 9305:SNAP23
uniprot id: A0A7N4NHV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

9305:LYVE1
gene id: 9305:LYVE1
uniprot id: G3VKY3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:GINS4
gene id: 9305:GINS4
uniprot id: A0A7N4NYA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

9305:MMS22L
gene id: 9305:MMS22L
uniprot id: G3WXB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

9305:SNX5
gene id: 9305:SNX5
uniprot id: G3X2K2
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

9305:GTF2H2
gene id: 9305:GTF2H2
uniprot id: A0A7N4PYE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

9305:LOC100931112
gene id: 9305:LOC100931112
uniprot id: A0A7N4V7D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LCAT
gene id: 9305:LCAT
uniprot id: G3W0U4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9305:LOC100929967
gene id: 9305:LOC100929967
uniprot id: G3VH33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:HEXA
gene id: 9305:HEXA
uniprot id: G3W2Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

9305:TEKT5
gene id: 9305:TEKT5
uniprot id: A0A7N4PB14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

9305:LOC100918000
gene id: 9305:LOC100918000
uniprot id: G3VJX7
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

9305:EZH2
gene id: 9305:EZH2
uniprot id: G3WZR8
uniprot id: G3WZR9
names: Subcellular Location Annotation
messages: Nucleus

9305:LYPD6
gene id: 9305:LYPD6
uniprot id: A0A7N4P9Q9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:SEC63
gene id: 9305:SEC63
uniprot id: G3WYZ2
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100928760
gene id: 9305:LOC100928760
uniprot id: A0A7N4NT77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

9305:ARL6
gene id: 9305:ARL6
uniprot id: A0A7N4NUT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

9305:TM2D2
gene id: 9305:TM2D2
uniprot id: G3X2J0
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100933078
gene id: 9305:LOC100933078
uniprot id: A0A7N4PTJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9305:WARS2
gene id: 9305:WARS2
uniprot id: G3WKV9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9305:ACSM3
gene id: 9305:ACSM3
uniprot id: A0A7N4PLG7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9305:LOC100928150
gene id: 9305:LOC100928150
uniprot id: G3WBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TIMM8A
gene id: 9305:TIMM8A
uniprot id: G3WKU9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9305:HIKESHI
gene id: 9305:HIKESHI
uniprot id: G3WJQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

9305:LOC100914102
gene id: 9305:LOC100914102
uniprot id: G3VRB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:GALNT12
gene id: 9305:GALNT12
uniprot id: G3WYU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9305:PLTP
gene id: 9305:PLTP
uniprot id: A0A7N4UYV2
names: Similarity
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

9305:PSEN2
gene id: 9305:PSEN2
uniprot id: G3W889
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

9305:GRAP
gene id: 9305:GRAP
uniprot id: G3WER2
names: Similarity
messages: Belongs to the GRB2/sem-5/DRK family.

9305:B3GNT2
gene id: 9305:B3GNT2
uniprot id: A0A7N4V5B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:GLO1
gene id: 9305:GLO1
uniprot id: A0A7N4P6M0
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

9305:TMED10
gene id: 9305:TMED10
uniprot id: A0A7N4PJQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:TADA1
gene id: 9305:TADA1
uniprot id: A0A7N4PZB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TADA1 family.
messages: Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

9305:KYAT3
gene id: 9305:KYAT3
uniprot id: G3VLY8
names: Subunit
messages: Homodimer.

9305:LOC100925548
gene id: 9305:LOC100925548
uniprot id: A0A7N4NJ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:CDC26
gene id: 9305:CDC26
uniprot id: A0A7N4P836
names: Function
names: Similarity
messages: Belongs to the CDC26 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

9305:LOC100930556
gene id: 9305:LOC100930556
uniprot id: A0A7N4PGD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ZFYVE26
gene id: 9305:ZFYVE26
uniprot id: G3WH22
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with AP5Z1, AP5B1, AP5S1 and SPG11. Interacts with TTC19 and KIF13A.
messages: Midbody
messages: Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair.

9305:AIMP2
gene id: 9305:AIMP2
uniprot id: G3WLJ4
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

9305:GLRA3
gene id: 9305:GLRA3
uniprot id: A0A7N4PVG9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

9305:SBK2
gene id: 9305:SBK2
uniprot id: A0A7N4P9S6
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:GABRA2
gene id: 9305:GABRA2
uniprot id: G3WIL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendrite

9305:CXCL8
gene id: 9305:CXCL8
uniprot id: G3WTP6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

9305:RHPN2
gene id: 9305:RHPN2
uniprot id: G3WUK3
names: Similarity
messages: Belongs to the RHPN family.

9305:YPEL2
gene id: 9305:YPEL2
uniprot id: A0A7N4PSZ5
names: Similarity
messages: Belongs to the yippee family.

9305:APH1B
gene id: 9305:APH1B
uniprot id: A0A7N4P7D8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

9305:MRPL54
gene id: 9305:MRPL54
uniprot id: G3VI85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

9305:USP45
gene id: 9305:USP45
uniprot id: G3WGY9
uniprot id: G3WGZ0
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9305:DBH
gene id: 9305:DBH
uniprot id: A0A7N4V4M9
uniprot id: G3W5W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Conversion of dopamine to noradrenaline.
messages: Homotetramer; composed of two disulfide-linked dimers.
messages: chromaffin granule lumen
messages: chromaffin granule membrane
messages: secretory vesicle lumen
messages: secretory vesicle membrane

9305:B3GNT3
gene id: 9305:B3GNT3
uniprot id: G3VLG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:MRPL58
gene id: 9305:MRPL58
uniprot id: A0A7N4P169
names: Subcellular Location Annotation
messages: Mitochondrion

9305:PSMD5
gene id: 9305:PSMD5
uniprot id: G3WXX1
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

9305:RPL37
gene id: 9305:RPL37
uniprot id: G3WLW3
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

9305:CPB1
gene id: 9305:CPB1
uniprot id: G3VV32
names: Similarity
messages: Belongs to the peptidase M14 family.

9305:NUP93
gene id: 9305:NUP93
uniprot id: G3WEE8
uniprot id: G3WEE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

9305:BAK1
gene id: 9305:BAK1
uniprot id: A0A7N4NH60
uniprot id: A0A7N4PCK9
names: Similarity
messages: Belongs to the Bcl-2 family.

9305:INPP5B
gene id: 9305:INPP5B
uniprot id: G3WMK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

9305:PHACTR4
gene id: 9305:PHACTR4
uniprot id: A0A7N4NZ13
uniprot id: G3VWC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

9305:CXXC5
gene id: 9305:CXXC5
uniprot id: G3WG38
names: Subcellular Location Annotation
messages: Cytoplasm

9305:RPS6
gene id: 9305:RPS6
uniprot id: A0A7N4PGN1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

9305:OGFOD1
gene id: 9305:OGFOD1
uniprot id: G3W7F1
names: Similarity
messages: Belongs to the TPA1 family.

9305:LOC100922058
gene id: 9305:LOC100922058
uniprot id: G3WF96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9305:SPIC
gene id: 9305:SPIC
uniprot id: G3VU21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9305:HAUS1
gene id: 9305:HAUS1
uniprot id: A0A7N4V7F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

9305:PPP2R5C
gene id: 9305:PPP2R5C
uniprot id: A0A7N4PU05
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

9305:LOC100915848
gene id: 9305:LOC100915848
uniprot id: G3VHL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MACIR
gene id: 9305:MACIR
uniprot id: G3VV77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UNC119-binding protein family.
messages: Cytoplasm
messages: cilium

9305:FAM20A
gene id: 9305:FAM20A
uniprot id: G3VZ47
names: Similarity
messages: Belongs to the FAM20 family.

9305:GABRP
gene id: 9305:GABRP
uniprot id: G3VDS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9305:SLC35B4
gene id: 9305:SLC35B4
uniprot id: G3VVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

9305:DVL2
gene id: 9305:DVL2
uniprot id: G3W2D2
names: Similarity
messages: Belongs to the DSH family.

9305:GPX8
gene id: 9305:GPX8
uniprot id: G3VQ14
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9305:RTCA
gene id: 9305:RTCA
uniprot id: A0A7N4NH01
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

9305:SOST
gene id: 9305:SOST
uniprot id: A0A7N4P365
names: Function
names: Similarity
names: Subunit
messages: Belongs to the sclerostin family.
messages: Interacts with LRP4 (via the extracellular domain); the interaction facilitates the inhibition of Wnt signaling. Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling. Interacts with LRP6.
messages: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

9305:CLIC3
gene id: 9305:CLIC3
uniprot id: G3W4L4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

9305:SLCO3A1
gene id: 9305:SLCO3A1
uniprot id: A0A7N4P2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

9305:LOC100927965
gene id: 9305:LOC100927965
uniprot id: G3VVE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MTG1
gene id: 9305:MTG1
uniprot id: G3WBK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Mitochondrion inner membrane
messages: Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity.

9305:LNPEP
gene id: 9305:LNPEP
uniprot id: G3VCX1
names: Similarity
messages: Belongs to the peptidase M1 family.

9305:LOC100913809
gene id: 9305:LOC100913809
uniprot id: A0A7N4NHF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100913560
gene id: 9305:LOC100913560
uniprot id: G3VL41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

9305:TSPAN5
gene id: 9305:TSPAN5
uniprot id: A0A7N4PG89
uniprot id: G3W9S7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:CCR4
gene id: 9305:CCR4
uniprot id: A0A7N4V669
uniprot id: G3VFP3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:PMM2
gene id: 9305:PMM2
uniprot id: A0A7N4UYD9
uniprot id: G3WHW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

9305:IRX4
gene id: 9305:IRX4
uniprot id: A0A7N4PRN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

9305:ADHFE1
gene id: 9305:ADHFE1
uniprot id: G3WDY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

9305:ACSF3
gene id: 9305:ACSF3
uniprot id: A0A7N4NSE7
uniprot id: G3WHV6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9305:KIF1C
gene id: 9305:KIF1C
uniprot id: G3VFP0
uniprot id: G3VFP1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9305:SPSB2
gene id: 9305:SPSB2
uniprot id: G3WU31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

9305:XKR9
gene id: 9305:XKR9
uniprot id: G3WJB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

9305:PYCR3
gene id: 9305:PYCR3
uniprot id: A0A7N4V1Q9
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

9305:TMEM267
gene id: 9305:TMEM267
uniprot id: A0A7N4NM44
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100919512
gene id: 9305:LOC100919512
uniprot id: G3VNG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:IDH1
gene id: 9305:IDH1
uniprot id: G3W9L8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

9305:LOC100923276
gene id: 9305:LOC100923276
uniprot id: G3W9P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100928328
gene id: 9305:LOC100928328
uniprot id: G3WC14
names: Similarity
messages: Belongs to the FAM122 family.

9305:IL1A
gene id: 9305:IL1A
uniprot id: G3W2K5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: Secreted

9305:SLC7A6OS
gene id: 9305:SLC7A6OS
uniprot id: G3VS60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

9305:TGFB2
gene id: 9305:TGFB2
uniprot id: G3WZB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

9305:VPS35
gene id: 9305:VPS35
uniprot id: G3VK89
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

9305:SLC16A11
gene id: 9305:SLC16A11
uniprot id: G3VDA0
names: Subcellular Location Annotation
messages: Membrane

9305:MRPL13
gene id: 9305:MRPL13
uniprot id: A0A7N4NM00
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

9305:PUS1
gene id: 9305:PUS1
uniprot id: A0A7N4Q0X0
uniprot id: G3WJ74
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

9305:P2RX7
gene id: 9305:P2RX7
uniprot id: G3WT47
uniprot id: G3WT48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9305:CA7
gene id: 9305:CA7
uniprot id: G3VKH8
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9305:LOC100923659
gene id: 9305:LOC100923659
uniprot id: A0A7N4PJJ8
names: Similarity
messages: Belongs to the TMEM14 family.

9305:RSPO1
gene id: 9305:RSPO1
uniprot id: G3WGZ4
names: Similarity
messages: Belongs to the R-spondin family.

9305:TMEM256
gene id: 9305:TMEM256
uniprot id: A0A7N4NMN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

9305:GLRA2
gene id: 9305:GLRA2
uniprot id: A0A7N4NX18
uniprot id: G3W4W7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

9305:FXN
gene id: 9305:FXN
uniprot id: A0A7N4NQC6
names: Similarity
messages: Belongs to the frataxin family.

9305:PSMB6
gene id: 9305:PSMB6
uniprot id: G3VIS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9305:STAT1
gene id: 9305:STAT1
uniprot id: G3WWX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9305:CYTB
gene id: 9305:CYTB
uniprot id: G1FKD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The cytochrome bc1 complex contains 11 subunits: 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of UQCRFS1). This cytochrome bc1 complex then forms a dimer.

9305:KIF22
gene id: 9305:KIF22
uniprot id: A0A7N4P3B0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9305:LOC100921435
gene id: 9305:LOC100921435
uniprot id: A0A7N4PDJ3
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

9305:ME3
gene id: 9305:ME3
uniprot id: G3WCM1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

9305:FASLG
gene id: 9305:FASLG
uniprot id: G3X251
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytoplasmic form induces gene transcription inhibition.
messages: Cytoplasmic vesicle lumen
messages: Lysosome lumen
messages: Nucleus
messages: Secreted

9305:ABCG4
gene id: 9305:ABCG4
uniprot id: G3W6B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

9305:BOLA1
gene id: 9305:BOLA1
uniprot id: G3VKU1
names: Similarity
messages: Belongs to the BolA/IbaG family.

9305:NR4A3
gene id: 9305:NR4A3
uniprot id: G3WK77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9305:PSKH1
gene id: 9305:PSKH1
uniprot id: G3VX66
names: Similarity
messages: Belongs to the protein kinase superfamily.

9305:NUP155
gene id: 9305:NUP155
uniprot id: G3WZE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

9305:MEA1
gene id: 9305:MEA1
uniprot id: A0A7N4PNN6
uniprot id: G3WEN2
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

9305:ABCG2
gene id: 9305:ABCG2
uniprot id: G3VHT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion membrane

9305:LOC100917762
gene id: 9305:LOC100917762
uniprot id: A0A7N4NM45
names: Similarity
messages: Belongs to the IUNH family.

9305:PYM1
gene id: 9305:PYM1
uniprot id: A0A7N4PWJ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pym family.
messages: Cytoplasm
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

9305:MBOAT2
gene id: 9305:MBOAT2
uniprot id: A0A7N4PHF1
uniprot id: G3WFK0
names: Subcellular Location Annotation
messages: Membrane

9305:EEF1A1
gene id: 9305:EEF1A1
uniprot id: A0A7N4PPS0
uniprot id: G3VQW3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

9305:INIP
gene id: 9305:INIP
uniprot id: A0A7N4PMB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

9305:EVPL
gene id: 9305:EVPL
uniprot id: G3WYM5
names: Subcellular Location Annotation
messages: cytoskeleton

9305:PROK1
gene id: 9305:PROK1
uniprot id: G3WCA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

9305:MAP1LC3C
gene id: 9305:MAP1LC3C
uniprot id: A0A7N4V5Z1
names: Similarity
messages: Belongs to the ATG8 family.

9305:DOLK
gene id: 9305:DOLK
uniprot id: G3X3R8
names: Similarity
messages: Belongs to the polyprenol kinase family.

9305:ZRANB1
gene id: 9305:ZRANB1
uniprot id: G3VT52
uniprot id: G3VT53
names: Similarity
messages: Belongs to the peptidase C64 family.

9305:LOC100924401
gene id: 9305:LOC100924401
uniprot id: G3W7Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100914330
gene id: 9305:LOC100914330
uniprot id: G3W4U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100919695
gene id: 9305:LOC100919695
uniprot id: A0A7N4NK16
uniprot id: G3WUU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

9305:PPARGC1A
gene id: 9305:PPARGC1A
uniprot id: A0A7N4PDV4
names: Subcellular Location Annotation
messages: PML body

9305:GET4
gene id: 9305:GET4
uniprot id: G3WJG0
names: Similarity
messages: Belongs to the GET4 family.

9305:RSL24D1
gene id: 9305:RSL24D1
uniprot id: A0A7N4V7C6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

9305:LOC100914760
gene id: 9305:LOC100914760
uniprot id: A0A7N4PHT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:FAH
gene id: 9305:FAH
uniprot id: G3WQ22
names: Similarity
messages: Belongs to the FAH family.

9305:MRPL10
gene id: 9305:MRPL10
uniprot id: A0A7N4NLV4
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

9305:TCTE3
gene id: 9305:TCTE3
uniprot id: A0A7N4P0F4
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9305:ITGAL
gene id: 9305:ITGAL
uniprot id: A0A7N4UYN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9305:LOC100932812
gene id: 9305:LOC100932812
uniprot id: G3WQ04
names: Similarity
messages: Belongs to the intermediate filament family.

9305:PWWP3A
gene id: 9305:PWWP3A
uniprot id: G3WLW9
names: Similarity
messages: Belongs to the PWWP3A family.

9305:OTUB2
gene id: 9305:OTUB2
uniprot id: A0A7N4P131
names: Similarity
messages: Belongs to the peptidase C65 family.

9305:TBX20
gene id: 9305:TBX20
uniprot id: A0A7N4NW62
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9305:CNN1
gene id: 9305:CNN1
uniprot id: G3VQ33
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

9305:IMPA2
gene id: 9305:IMPA2
uniprot id: A0A7N4NHG5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9305:DRAXIN
gene id: 9305:DRAXIN
uniprot id: G3W7G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
messages: Interacts with LRP6.
messages: Secreted

9305:FABP2
gene id: 9305:FABP2
uniprot id: G3WB52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.

9305:FAM83D
gene id: 9305:FAM83D
uniprot id: G3WSA4
names: Similarity
messages: Belongs to the FAM83 family.

9305:LOC100925379
gene id: 9305:LOC100925379
uniprot id: A0A7N4NRG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:P2RY13
gene id: 9305:P2RY13
uniprot id: A0A7N4P8E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:PROM2
gene id: 9305:PROM2
uniprot id: G3WAK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

9305:MTMR8
gene id: 9305:MTMR8
uniprot id: G3VDJ9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9305:MAK16
gene id: 9305:MAK16
uniprot id: G3W012
names: Similarity
messages: Belongs to the MAK16 family.

9305:NME7
gene id: 9305:NME7
uniprot id: A0A7N4NRS5
uniprot id: G3VTT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: cilium axoneme

9305:LOC100931126
gene id: 9305:LOC100931126
uniprot id: A0A7N4V048
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TDP1
gene id: 9305:TDP1
uniprot id: G3VQW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

9305:NME5
gene id: 9305:NME5
uniprot id: A0A7N4PBN9
names: Similarity
messages: Belongs to the NDK family.

9305:CGA
gene id: 9305:CGA
uniprot id: G3VYZ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer. The active hormones thyrotropin, lutropin and follitropin are heterodimers composed of CGA, a common alpha chain described here and a unique beta chain which confers their biological specificity to the hormones: TSHB for thyrotropin, LHB for lutropin and FSHB for follitropin.
messages: Secreted

9305:NSUN2
gene id: 9305:NSUN2
uniprot id: G3WBW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: extracellular exosome

9305:MPHOSPH10
gene id: 9305:MPHOSPH10
uniprot id: G3WVR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

9305:PSMA5
gene id: 9305:PSMA5
uniprot id: G3X0Z9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9305:FSCN3
gene id: 9305:FSCN3
uniprot id: G3WQP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

9305:LOC100918041
gene id: 9305:LOC100918041
uniprot id: A0A7N4PVP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9305:LOC100920521
gene id: 9305:LOC100920521
uniprot id: A0A7N4V1U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

9305:MOGAT2
gene id: 9305:MOGAT2
uniprot id: G3VDN0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:TSPAN1
gene id: 9305:TSPAN1
uniprot id: A0A7N4PHZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9305:AARS2
gene id: 9305:AARS2
uniprot id: G3WYZ7
names: Caution
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: ISGylated.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

9305:TIMM17B
gene id: 9305:TIMM17B
uniprot id: G3VEY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

9305:HS3ST1
gene id: 9305:HS3ST1
uniprot id: G3W857
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9305:SYNJ1
gene id: 9305:SYNJ1
uniprot id: A0A7N4PJ74
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

9305:METTL15
gene id: 9305:METTL15
uniprot id: G3WTP3
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

9305:LOC100913284
gene id: 9305:LOC100913284
uniprot id: A0A7N4PWI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:FAHD2A
gene id: 9305:FAHD2A
uniprot id: G3W4N2
names: Similarity
messages: Belongs to the FAH family.

9305:NUTM1
gene id: 9305:NUTM1
uniprot id: G3VMN0
names: Similarity
messages: Belongs to the NUT family.

9305:OPRD1
gene id: 9305:OPRD1
uniprot id: A0A7N4NYE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100927993
gene id: 9305:LOC100927993
uniprot id: G3VLB7
names: Similarity
messages: Belongs to the serpin family.

9305:LOC100915011
gene id: 9305:LOC100915011
uniprot id: G3WM89
names: Similarity
messages: Belongs to the intermediate filament family.

9305:TEKT3
gene id: 9305:TEKT3
uniprot id: G3WS64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

9305:SDAD1
gene id: 9305:SDAD1
uniprot id: G3VIU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

9305:TM4SF20
gene id: 9305:TM4SF20
uniprot id: G3WF49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9305:IL1B
gene id: 9305:IL1B
uniprot id: G3W4G1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: IL1B production occurs in 2 steps, each being controlled by different stimuli. First, inflammatory signals, such as LPS, stimulate the synthesis and promote the accumulation of cytosolic stores of pro-IL1B (priming). Then additional signals are required for inflammasome assembly, leading to CASP1 activation, pro-IL1B processing and eventually secretion of the active cytokine. IL1B processing and secretion are temporarily associated.
messages: Lysosome
messages: Monomer. Interacts with MEFV.
messages: Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
messages: Secreted
messages: cytosol
messages: extracellular exosome

9305:CHRNB4
gene id: 9305:CHRNB4
uniprot id: G3WY62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9305:RIPOR2
gene id: 9305:RIPOR2
uniprot id: A0A7N4V7X9
uniprot id: G3VXK2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the RIPOR family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: stereocilium membrane

9305:LOC100917708
gene id: 9305:LOC100917708
uniprot id: G3VV00
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:FGF23
gene id: 9305:FGF23
uniprot id: A0A7N4PC55
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9305:GLRX
gene id: 9305:GLRX
uniprot id: A0A7N4V0D0
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

9305:LOC100934244
gene id: 9305:LOC100934244
uniprot id: G3WWE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LITAF
gene id: 9305:LITAF
uniprot id: A0A7N4NP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

9305:SLC35A1
gene id: 9305:SLC35A1
uniprot id: G3W9J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

9305:ALG5
gene id: 9305:ALG5
uniprot id: G3VNR5
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

9305:LYG1
gene id: 9305:LYG1
uniprot id: G3W6E3
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

9305:SNX7
gene id: 9305:SNX7
uniprot id: A0A7N4NYJ1
uniprot id: G3VI05
names: Similarity
messages: Belongs to the sorting nexin family.

9305:ATP2B3
gene id: 9305:ATP2B3
uniprot id: G3VTR7
uniprot id: G3VTR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:LOC100917257
gene id: 9305:LOC100917257
uniprot id: A0A7N4NH53
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

9305:GRPEL1
gene id: 9305:GRPEL1
uniprot id: A0A7N4PVP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

9305:LOC100933766
gene id: 9305:LOC100933766
uniprot id: G3WMU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9305:LANCL1
gene id: 9305:LANCL1
uniprot id: A0A7N4PSS3
uniprot id: G3WZX7
names: Similarity
messages: Belongs to the LanC-like protein family.

9305:ITPKB
gene id: 9305:ITPKB
uniprot id: A0A7N4P3K9
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9305:LOC100933226
gene id: 9305:LOC100933226
uniprot id: G3X1S0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9305:BHMT2
gene id: 9305:BHMT2
uniprot id: A0A7N4PFG4
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

9305:MTRF1
gene id: 9305:MTRF1
uniprot id: A0A7N4PXV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

9305:GPR158
gene id: 9305:GPR158
uniprot id: A0A7N4PYE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

9305:AMZ1
gene id: 9305:AMZ1
uniprot id: G3WH89
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

9305:PYCR1
gene id: 9305:PYCR1
uniprot id: A0A7N4NXQ3
uniprot id: G3W6V6
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

9305:TADA2A
gene id: 9305:TADA2A
uniprot id: A0A7N4V6L7
uniprot id: G3WIE3
names: Subcellular Location Annotation
messages: Nucleus

9305:ROR2
gene id: 9305:ROR2
uniprot id: A0A7N4P3Q4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:LOC100923899
gene id: 9305:LOC100923899
uniprot id: A0A7N4NIK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ESRRB
gene id: 9305:ESRRB
uniprot id: G3WKX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9305:LOC100916224
gene id: 9305:LOC100916224
uniprot id: A0A7N4V632
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:DPYSL2
gene id: 9305:DPYSL2
uniprot id: G3W2B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Homotetramer, and heterotetramer with CRMP1, DPYSL3, DPYSL4 or DPYSL5. Interacts through its C-terminus with the C-terminus of CYFIP1/SRA1. Interacts with HTR4. Interacts with CLN6. Interacts with MICALL1.
messages: Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.

9305:LOC100913970
gene id: 9305:LOC100913970
uniprot id: G3W6F8
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:S100A2
gene id: 9305:S100A2
uniprot id: G3W673
names: Similarity
messages: Belongs to the S-100 family.

9305:SNAPIN
gene id: 9305:SNAPIN
uniprot id: A0A7N4PBC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAPIN family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling.
messages: synaptic vesicle membrane

9305:NEUROD6
gene id: 9305:NEUROD6
uniprot id: G3W7F7
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

9305:LOC100926505
gene id: 9305:LOC100926505
uniprot id: G3WI29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.

9305:PLCB2
gene id: 9305:PLCB2
uniprot id: G3WJX3
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

9305:DOHH
gene id: 9305:DOHH
uniprot id: G3W423
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

9305:LOC100934629
gene id: 9305:LOC100934629
uniprot id: G3VHA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornifin (SPRR) family.
messages: Cytoplasm

9305:LIAS
gene id: 9305:LIAS
uniprot id: A0A7N4UYM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

9305:CENPX
gene id: 9305:CENPX
uniprot id: A0A7N4PA68
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

9305:LOC100926253
gene id: 9305:LOC100926253
uniprot id: G3VS86
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9305:IDH3G
gene id: 9305:IDH3G
uniprot id: G3VDI2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

9305:LEPROT
gene id: 9305:LEPROT
uniprot id: A0A7N4P0S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

9305:TMOD3
gene id: 9305:TMOD3
uniprot id: A0A7N4UY26
uniprot id: G3WWB5
names: Subcellular Location Annotation
messages: cytoskeleton

9305:IGFBP4
gene id: 9305:IGFBP4
uniprot id: G3WEN7
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:B3GALNT1
gene id: 9305:B3GALNT1
uniprot id: G3WUQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:LOC100921066
gene id: 9305:LOC100921066
uniprot id: G3W3U8
names: Subcellular Location Annotation
messages: Membrane

9305:POGLUT2
gene id: 9305:POGLUT2
uniprot id: G3WF10
names: Similarity
messages: Belongs to the KDELC family.

9305:SCARB2
gene id: 9305:SCARB2
uniprot id: A0A7N4NIW8
names: Similarity
messages: Belongs to the CD36 family.

9305:UBLCP1
gene id: 9305:UBLCP1
uniprot id: G3X3H9
names: Function
names: Subcellular Location Annotation
messages: Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.
messages: Nucleus

9305:DIP2C
gene id: 9305:DIP2C
uniprot id: A0A7N4NKK4
names: Similarity
messages: Belongs to the DIP2 family.

9305:CRYGN
gene id: 9305:CRYGN
uniprot id: G3VJJ3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

9305:LOC100927430
gene id: 9305:LOC100927430
uniprot id: G3VS03
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

9305:LOC100916712
gene id: 9305:LOC100916712
uniprot id: G3VA05
names: Similarity
messages: Belongs to the actin family.

9305:TPMT
gene id: 9305:TPMT
uniprot id: A0A7N4PUT2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm
messages: Monomer.

9305:INTS7
gene id: 9305:INTS7
uniprot id: G3VFT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus

9305:IKBKE
gene id: 9305:IKBKE
uniprot id: G3WZ29
names: Subcellular Location Annotation
messages: Cytoplasm

9305:LOC100919087
gene id: 9305:LOC100919087
uniprot id: A0A7N4NZD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9305:LOC100935414
gene id: 9305:LOC100935414
uniprot id: G3VXJ4
names: Similarity
messages: Belongs to the TMEM176 family.

9305:LOC100927633
gene id: 9305:LOC100927633
uniprot id: G3W7X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:NOP14
gene id: 9305:NOP14
uniprot id: G3WBE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

9305:LOC100919998
gene id: 9305:LOC100919998
uniprot id: A0A7N4P9W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:SPARC
gene id: 9305:SPARC
uniprot id: G3VZ19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

9305:APOH
gene id: 9305:APOH
uniprot id: G3VSZ3
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9305:TDO2
gene id: 9305:TDO2
uniprot id: G3VJX9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:MBOAT4
gene id: 9305:MBOAT4
uniprot id: A0A7N4Q1R9
names: Subcellular Location Annotation
messages: Membrane

9305:COPB2
gene id: 9305:COPB2
uniprot id: A0A7N4NVA7
uniprot id: G3WCJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

9305:EEF1AKMT1
gene id: 9305:EEF1AKMT1
uniprot id: G3VUX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

9305:EFNA5
gene id: 9305:EFNA5
uniprot id: A0A7N4PLT4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:DKC1
gene id: 9305:DKC1
uniprot id: G3VHY1
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

9305:LOC100924585
gene id: 9305:LOC100924585
uniprot id: G3WEN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:OLFM3
gene id: 9305:OLFM3
uniprot id: G3WPL4
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

9305:LRP12
gene id: 9305:LRP12
uniprot id: G3WK40
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:RPL37A
gene id: 9305:RPL37A
uniprot id: A0A7N4NMK6
uniprot id: G3WJZ0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

9305:EZR
gene id: 9305:EZR
uniprot id: G3W6E9
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

9305:LYG2
gene id: 9305:LYG2
uniprot id: A0A7N4UYT0
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

9305:LOC100928819
gene id: 9305:LOC100928819
uniprot id: A0A7N4PLI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

9305:BCL2L1
gene id: 9305:BCL2L1
uniprot id: G3WKX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane
messages: Mitochondrion matrix
messages: Nucleus membrane
messages: centrosome
messages: cytosol
messages: synaptic vesicle membrane

9305:SEPTIN9
gene id: 9305:SEPTIN9
uniprot id: G3VWH9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

9305:SLC37A4
gene id: 9305:SLC37A4
uniprot id: G3W9X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

9305:DACT1
gene id: 9305:DACT1
uniprot id: G3X297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dapper family.
messages: Cytoplasm

9305:PSMA3
gene id: 9305:PSMA3
uniprot id: G3X0H5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9305:LOC100931976
gene id: 9305:LOC100931976
uniprot id: G3VFS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

9305:DPM2
gene id: 9305:DPM2
uniprot id: A0A7N4PM74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

9305:OSBPL9
gene id: 9305:OSBPL9
uniprot id: A0A7N4V155
uniprot id: G3VP12
names: Similarity
messages: Belongs to the OSBP family.

9305:KIF5A
gene id: 9305:KIF5A
uniprot id: A0A7N4NZQ8
uniprot id: G3W0A8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9305:LYPD6B
gene id: 9305:LYPD6B
uniprot id: G3WG58
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:G6PC
gene id: 9305:G6PC
uniprot id: A0A7N4PK76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

9305:XKR5
gene id: 9305:XKR5
uniprot id: G3VG39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

9305:MTRF1L
gene id: 9305:MTRF1L
uniprot id: A0A7N4UX32
uniprot id: G3X0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

9305:TNS4
gene id: 9305:TNS4
uniprot id: G3WCW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

9305:CDC5L
gene id: 9305:CDC5L
uniprot id: G3WZE7
names: Similarity
messages: Belongs to the CEF1 family.

9305:CD5L
gene id: 9305:CD5L
uniprot id: G3VVS4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:HAS2
gene id: 9305:HAS2
uniprot id: G3W3U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NodC/HAS family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane

9305:TLR4
gene id: 9305:TLR4
uniprot id: G3WXY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9305:UVSSA
gene id: 9305:UVSSA
uniprot id: A0A7N4PQ44
names: Similarity
messages: Belongs to the UVSSA family.

9305:HSF2
gene id: 9305:HSF2
uniprot id: G3WK53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9305:CCR7
gene id: 9305:CCR7
uniprot id: A0A7N4V6I9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:LOC100921536
gene id: 9305:LOC100921536
uniprot id: A0A7N4P178
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100930044
gene id: 9305:LOC100930044
uniprot id: G3X129
uniprot id: G3X1G8
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9305:PTK2B
gene id: 9305:PTK2B
uniprot id: A0A7N4P5K2
uniprot id: G3VFW4
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

9305:PTGR2
gene id: 9305:PTGR2
uniprot id: A0A7N4NN41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

9305:LOC100928021
gene id: 9305:LOC100928021
uniprot id: G3VPF3
names: Subcellular Location Annotation
messages: Membrane

9305:MRPL27
gene id: 9305:MRPL27
uniprot id: A0A7N4NXZ5
uniprot id: G3VNQ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

9305:INSIG2
gene id: 9305:INSIG2
uniprot id: G3X2R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

9305:LOC100932623
gene id: 9305:LOC100932623
uniprot id: G3VZ13
names: Similarity
messages: Belongs to the intermediate filament family.

9305:CREB3L4
gene id: 9305:CREB3L4
uniprot id: G3WE97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:ANTXR2
gene id: 9305:ANTXR2
uniprot id: G3X1V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

9305:LOC100921472
gene id: 9305:LOC100921472
uniprot id: A0A7N4UXQ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100926652
gene id: 9305:LOC100926652
uniprot id: A0A7N4NVB3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9305:BYSL
gene id: 9305:BYSL
uniprot id: G3VMU2
names: Similarity
messages: Belongs to the bystin family.

9305:CDH7
gene id: 9305:CDH7
uniprot id: G3W7N1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9305:NCAPH2
gene id: 9305:NCAPH2
uniprot id: G3VAL8
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

9305:LOC100929415
gene id: 9305:LOC100929415
uniprot id: G3VUZ8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:ATP2B4
gene id: 9305:ATP2B4
uniprot id: A0A7N4PKS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:PLA2G2D
gene id: 9305:PLA2G2D
uniprot id: G3WHN2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9305:CENPK
gene id: 9305:CENPK
uniprot id: G3WDR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

9305:CCNB1
gene id: 9305:CCNB1
uniprot id: G3W0C2
names: Similarity
messages: Belongs to the cyclin family.

9305:DCLRE1B
gene id: 9305:DCLRE1B
uniprot id: G3WJ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

9305:TBCE
gene id: 9305:TBCE
uniprot id: G3WPN9
uniprot id: G3WPP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

9305:TUBGCP5
gene id: 9305:TUBGCP5
uniprot id: A0A7N4PAT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

9305:PLSCR3
gene id: 9305:PLSCR3
uniprot id: G3VTV2
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

9305:TNFAIP3
gene id: 9305:TNFAIP3
uniprot id: G3W9V9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9305:CCDC39
gene id: 9305:CCDC39
uniprot id: G3X264
names: Similarity
messages: Belongs to the CCDC39 family.

9305:ATP5PD
gene id: 9305:ATP5PD
uniprot id: G3X351
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

9305:GAD2
gene id: 9305:GAD2
uniprot id: G3WJK8
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9305:MED31
gene id: 9305:MED31
uniprot id: A0A7N4PIC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

9305:HPS5
gene id: 9305:HPS5
uniprot id: G3WTX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

9305:PSMA1
gene id: 9305:PSMA1
uniprot id: A0A7N4PNL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9305:HOXC11
gene id: 9305:HOXC11
uniprot id: A0A7N4PF54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9305:KIF3B
gene id: 9305:KIF3B
uniprot id: A0A7N4PM20
uniprot id: G3WA27
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9305:LOC100923741
gene id: 9305:LOC100923741
uniprot id: A0A7N4NI86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ZSCAN29
gene id: 9305:ZSCAN29
uniprot id: G3WHW8
names: Function
messages: May be involved in transcriptional regulation.

9305:CLDN25
gene id: 9305:CLDN25
uniprot id: G3WIL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

9305:SCNN1G
gene id: 9305:SCNN1G
uniprot id: G3W678
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100923639
gene id: 9305:LOC100923639
uniprot id: A0A7N4NTK9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9305:LOC100917166
gene id: 9305:LOC100917166
uniprot id: G3VGG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100933995
gene id: 9305:LOC100933995
uniprot id: G3WDK7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

9305:PSD
gene id: 9305:PSD
uniprot id: G3X3K4
uniprot id: G3X3L2
names: Subcellular Location Annotation
messages: ruffle membrane

9305:WNT16
gene id: 9305:WNT16
uniprot id: A0A7N4UYI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9305:TDP2
gene id: 9305:TDP2
uniprot id: A0A7N4NFI6
names: Subcellular Location Annotation
messages: PML body

9305:EDN2
gene id: 9305:EDN2
uniprot id: G3VTC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

9305:GRN
gene id: 9305:GRN
uniprot id: G3WTW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

9305:TSR1
gene id: 9305:TSR1
uniprot id: G3WD22
names: Subcellular Location Annotation
messages: nucleolus

9305:SYNDIG1
gene id: 9305:SYNDIG1
uniprot id: A0A7N4PI17
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9305:PTPN4
gene id: 9305:PTPN4
uniprot id: A0A7N4PD16
uniprot id: G3WN40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: May act at junctions between the membrane and the cytoskeleton.
messages: cytoskeleton

9305:SLC15A5
gene id: 9305:SLC15A5
uniprot id: A0A7N4PUP9
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

9305:TMBIM6
gene id: 9305:TMBIM6
uniprot id: A0A7N4NYB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9305:ANTXR1
gene id: 9305:ANTXR1
uniprot id: A0A7N4NL41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

9305:SLC20A2
gene id: 9305:SLC20A2
uniprot id: A0A7N4PPI7
uniprot id: A0A7N4PTD1
uniprot id: G3X0Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

9305:LOC100916049
gene id: 9305:LOC100916049
uniprot id: A0A7N4V2K5
uniprot id: G3WPD7
names: Similarity
messages: Belongs to the intermediate filament family.

9305:FRK
gene id: 9305:FRK
uniprot id: A0A7N4PBP1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9305:MRPS14
gene id: 9305:MRPS14
uniprot id: A0A7N4V557
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

9305:CLDN6
gene id: 9305:CLDN6
uniprot id: G3WYY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9305:LOC100919646
gene id: 9305:LOC100919646
uniprot id: G3X2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:MDFIC
gene id: 9305:MDFIC
uniprot id: A0A7N4NFP5
names: Similarity
messages: Belongs to the MDFI family.

9305:NR3C1
gene id: 9305:NR3C1
uniprot id: G3VFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

9305:SCAMP4
gene id: 9305:SCAMP4
uniprot id: A0A7N4PCT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

9305:MOCS1
gene id: 9305:MOCS1
uniprot id: A0A7N4PX61
names: Similarity
messages: In the C-terminal section; belongs to the MoaC family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.

9305:THRSP
gene id: 9305:THRSP
uniprot id: G3WIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

9305:EXT1
gene id: 9305:EXT1
uniprot id: A0A7N4P943
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Forms a homo/heterooligomeric complex with EXT2. Interacts with NDST1.
messages: cis-Golgi network membrane

9305:THRB
gene id: 9305:THRB
uniprot id: G3VNI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9305:LOC100927088
gene id: 9305:LOC100927088
uniprot id: G3VNX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9305:AOC1
gene id: 9305:AOC1
uniprot id: G3W0I7
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

9305:PTGES
gene id: 9305:PTGES
uniprot id: A0A7N4P8B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

9305:RPS17
gene id: 9305:RPS17
uniprot id: G3WM06
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

9305:FAM53A
gene id: 9305:FAM53A
uniprot id: G3WNK1
names: Similarity
messages: Belongs to the FAM53 family.

9305:LOC100914020
gene id: 9305:LOC100914020
uniprot id: G3VQ51
names: Similarity
messages: Belongs to the DEAD box helicase family.

9305:ALOX5AP
gene id: 9305:ALOX5AP
uniprot id: G3WR31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:LOC100929420
gene id: 9305:LOC100929420
uniprot id: A0A7N4NKA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9305:LOC105750956
gene id: 9305:LOC105750956
uniprot id: G3W669
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:RGS4
gene id: 9305:RGS4
uniprot id: A0A7N4PNW9
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.

9305:BORA
gene id: 9305:BORA
uniprot id: G3WQL8
names: Similarity
messages: Belongs to the BORA family.

9305:MIP
gene id: 9305:MIP
uniprot id: G3VI04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

9305:RPGRIP1L
gene id: 9305:RPGRIP1L
uniprot id: G3W237
uniprot id: G3W238
names: Similarity
messages: Belongs to the RPGRIP1 family.

9305:ETFB
gene id: 9305:ETFB
uniprot id: A0A7N4PCC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

9305:HAPLN3
gene id: 9305:HAPLN3
uniprot id: G3WV87
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:PIANP
gene id: 9305:PIANP
uniprot id: G3WRY2
names: Subcellular Location Annotation
messages: Membrane

9305:TUT7
gene id: 9305:TUT7
uniprot id: A0A7N4NMP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

9305:LOC100934777
gene id: 9305:LOC100934777
uniprot id: G3WBN1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

9305:LOC100921946
gene id: 9305:LOC100921946
uniprot id: A0A7N4NG24
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:GET3
gene id: 9305:GET3
uniprot id: G3WSW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer. Component of a transmembrane domain recognition complex (TRC). Interacts with SERP1 and SEC61B. Interacts with WRB.
messages: nucleolus

9305:TBCCD1
gene id: 9305:TBCCD1
uniprot id: G3W8E5
uniprot id: G3W8E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

9305:LEAP2
gene id: 9305:LEAP2
uniprot id: G3WJ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

9305:ITGA7
gene id: 9305:ITGA7
uniprot id: A0A7N4NJ47
uniprot id: A0A7N4PUP2
uniprot id: G3W6Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9305:NOXA1
gene id: 9305:NOXA1
uniprot id: G3WET3
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

9305:RAMP3
gene id: 9305:RAMP3
uniprot id: A0A7N4PMX1
names: Similarity
messages: Belongs to the RAMP family.

9305:B4GALNT1
gene id: 9305:B4GALNT1
uniprot id: G3W2H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9305:PIGU
gene id: 9305:PIGU
uniprot id: G3WZA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

9305:HAPLN1
gene id: 9305:HAPLN1
uniprot id: A0A7N4P8V8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:SEC61B
gene id: 9305:SEC61B
uniprot id: A0A7N4NT22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

9305:ACTR1A
gene id: 9305:ACTR1A
uniprot id: A0A7N4UZD5
uniprot id: G3X3J0
names: Similarity
messages: Belongs to the actin family.

9305:GPAM
gene id: 9305:GPAM
uniprot id: G3X2Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
messages: Mitochondrion outer membrane

9305:CA4
gene id: 9305:CA4
uniprot id: A0A7N4NSE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cell membrane
messages: Interacts with SLC4A4.
messages: Membrane
messages: Reversible hydration of carbon dioxide.

9305:LOC100919803
gene id: 9305:LOC100919803
uniprot id: A0A7N4PSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100920690
gene id: 9305:LOC100920690
uniprot id: G3VFQ0
uniprot id: G3VJ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:APTX
gene id: 9305:APTX
uniprot id: A0A7N4P042
names: Subcellular Location Annotation
messages: nucleolus
messages: nucleoplasm

9305:KCNH4
gene id: 9305:KCNH4
uniprot id: G3VQL5
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

9305:SNX2
gene id: 9305:SNX2
uniprot id: G3WI42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium

9305:APLP2
gene id: 9305:APLP2
uniprot id: G3VZN8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:FAM187A
gene id: 9305:FAM187A
uniprot id: G3W388
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

9305:RBP7
gene id: 9305:RBP7
uniprot id: G3W8U3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9305:LOC100916439
gene id: 9305:LOC100916439
uniprot id: G3WNF4
names: Similarity
messages: Belongs to the 2-5A synthase family.

9305:ARPC2
gene id: 9305:ARPC2
uniprot id: A0A7N4PUX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with SHANK3; the interaction probably mediates the association of SHANK3 with the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

9305:LIN52
gene id: 9305:LIN52
uniprot id: A0A7N4P7H4
names: Similarity
messages: Belongs to the lin-52 family.

9305:CTSE
gene id: 9305:CTSE
uniprot id: G3WWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A1 family.
messages: Endosome
messages: Homodimer; disulfide-linked.
messages: May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.

9305:DPT
gene id: 9305:DPT
uniprot id: A0A7N4PPJ4
uniprot id: G3VE98
names: Similarity
messages: Belongs to the dermatopontin family.

9305:LOC100918565
gene id: 9305:LOC100918565
uniprot id: G3WIL7
uniprot id: G3WK08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC105748988
gene id: 9305:LOC105748988
uniprot id: G3VUU7
names: Similarity
messages: Belongs to the intermediate filament family.

9305:LOC100918500
gene id: 9305:LOC100918500
uniprot id: G3VK62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100923647
gene id: 9305:LOC100923647
uniprot id: A0A7N4V1H3
names: Subcellular Location Annotation
messages: Membrane

9305:JAK3
gene id: 9305:JAK3
uniprot id: G3VR92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

9305:MAP3K8
gene id: 9305:MAP3K8
uniprot id: G3VGB5
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

9305:LOC100929481
gene id: 9305:LOC100929481
uniprot id: M1ZMK8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

9305:APPL2
gene id: 9305:APPL2
uniprot id: G3W7E7
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Nucleus
messages: phagosome
messages: ruffle

9305:SEMA4A
gene id: 9305:SEMA4A
uniprot id: G3WLB2
names: Similarity
messages: Belongs to the semaphorin family.

9305:CAP1
gene id: 9305:CAP1
uniprot id: A0A7N4NT93
uniprot id: G3VF71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.
messages: Homodimer. Binds actin monomers.
messages: Membrane

9305:PARD6B
gene id: 9305:PARD6B
uniprot id: G3X3I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

9305:NIBAN1
gene id: 9305:NIBAN1
uniprot id: G3VSI7
names: Similarity
messages: Belongs to the Niban family.

9305:EDNRB
gene id: 9305:EDNRB
uniprot id: G3W138
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:IYD
gene id: 9305:IYD
uniprot id: G3VRG0
names: Subcellular Location Annotation
messages: Cell membrane

9305:WDR24
gene id: 9305:WDR24
uniprot id: G3WAT9
names: Similarity
messages: Belongs to the WD repeat WDR24 family.

9305:LRRC51
gene id: 9305:LRRC51
uniprot id: A0A7N4NS50
uniprot id: G3VJP9
names: Subcellular Location Annotation
messages: Cytoplasm

9305:PLIN2
gene id: 9305:PLIN2
uniprot id: A0A7N4PR72
uniprot id: G3WPQ3
names: Similarity
messages: Belongs to the perilipin family.

9305:RPS2
gene id: 9305:RPS2
uniprot id: G3WR67
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.

9305:SGMS2
gene id: 9305:SGMS2
uniprot id: G3VXB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

9305:FGFBP1
gene id: 9305:FGFBP1
uniprot id: G3X2B2
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

9305:IL10
gene id: 9305:IL10
uniprot id: G3X0Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

9305:TAAR1
gene id: 9305:TAAR1
uniprot id: A0A7N4V164
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9305:ATP1B2
gene id: 9305:ATP1B2
uniprot id: G3WS92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

9305:CCDC124
gene id: 9305:CCDC124
uniprot id: A0A7N4PN25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CCDC124 family.
messages: Interacts with RASGEF1B.
messages: Required for proper progression of late cytokinetic stages.

9305:LOC100931482
gene id: 9305:LOC100931482
uniprot id: G3VC95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9305:LOC100919505
gene id: 9305:LOC100919505
uniprot id: G3VWU8
names: Similarity
messages: Belongs to the IUNH family.

9305:PPIL1
gene id: 9305:PPIL1
uniprot id: A0A7N4P6X9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9305:COQ4
gene id: 9305:COQ4
uniprot id: A0A7N4PUM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

9305:LOC100927115
gene id: 9305:LOC100927115
uniprot id: G3W6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100917686
gene id: 9305:LOC100917686
uniprot id: G3VJW7
names: Subcellular Location Annotation
messages: Membrane

9305:MARK3
gene id: 9305:MARK3
uniprot id: G3WVQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

9305:TLCD3B
gene id: 9305:TLCD3B
uniprot id: G3WA54
uniprot id: G3WA55
names: Subcellular Location Annotation
messages: Membrane

9305:SLC25A23
gene id: 9305:SLC25A23
uniprot id: A0A7N4V0I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

9305:SLC35B3
gene id: 9305:SLC35B3
uniprot id: G3W616
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

9305:C1GALT1
gene id: 9305:C1GALT1
uniprot id: A0A7N4P5V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.
messages: Membrane

9305:LOC100934469
gene id: 9305:LOC100934469
uniprot id: A0A7N4NL37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ORC3
gene id: 9305:ORC3
uniprot id: G3WBD1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

9305:ESR2
gene id: 9305:ESR2
uniprot id: G3W1Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9305:LOC100914876
gene id: 9305:LOC100914876
uniprot id: A0A7N4PPB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:EVA1B
gene id: 9305:EVA1B
uniprot id: G3X0J8
names: Similarity
messages: Belongs to the EVA1 family.

9305:DR1
gene id: 9305:DR1
uniprot id: A0A7N4NWF1
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

9305:GDF10
gene id: 9305:GDF10
uniprot id: A0A7N4NXQ9
names: Similarity
messages: Belongs to the TGF-beta family.

9305:LOC100923805
gene id: 9305:LOC100923805
uniprot id: G3WLA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9305:SCAMP1
gene id: 9305:SCAMP1
uniprot id: G3WX15
uniprot id: G3WX16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

9305:FXR2
gene id: 9305:FXR2
uniprot id: G3WSR1
names: Similarity
messages: Belongs to the FMR1 family.

9305:INTS12
gene id: 9305:INTS12
uniprot id: G3VLG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Integrator subunit 12 family.
messages: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, INTS11/CPSF3L and INTS12.
messages: Nucleus

9305:VPS33A
gene id: 9305:VPS33A
uniprot id: A0A7N4PDC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

9305:BMP1
gene id: 9305:BMP1
uniprot id: A0A7N4PL80
uniprot id: G3X157
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:MAPK4
gene id: 9305:MAPK4
uniprot id: A0A7N4PRM6
uniprot id: G3WIM4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

9305:RBP4
gene id: 9305:RBP4
uniprot id: G3WX74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Interacts with TTR.
messages: Retinol-binding protein that mediates retinol transport in blood plasma.
messages: Secreted

9305:FYN
gene id: 9305:FYN
uniprot id: A0A7N4PRT3
uniprot id: G3WAB1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9305:PSPN
gene id: 9305:PSPN
uniprot id: A0A7N4NKR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

9305:HEPH
gene id: 9305:HEPH
uniprot id: A0A7N4NQH8
uniprot id: G3VFK7
names: Similarity
messages: Belongs to the multicopper oxidase family.

9305:ZADH2
gene id: 9305:ZADH2
uniprot id: G3WNM1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

9305:S100A11
gene id: 9305:S100A11
uniprot id: A0A7N4NHB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the S-100 family.
messages: Facilitates the differentiation and the cornification of keratinocytes.
messages: Homodimer; disulfide-linked.

9305:PLXNB2
gene id: 9305:PLXNB2
uniprot id: G3W8L6
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9305:LOC100914857
gene id: 9305:LOC100914857
uniprot id: A0A7N4Q0X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:ANAPC4
gene id: 9305:ANAPC4
uniprot id: G3VL08
names: Function
names: Similarity
messages: Belongs to the APC4 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

9305:MAT1A
gene id: 9305:MAT1A
uniprot id: A0A7N4P9J6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

9305:SEC23B
gene id: 9305:SEC23B
uniprot id: A0A7N4PPN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9305:MET
gene id: 9305:MET
uniprot id: G3WTF3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9305:COPS5
gene id: 9305:COPS5
uniprot id: A0A7N4NZY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

9305:AVPR1A
gene id: 9305:AVPR1A
uniprot id: G3VT25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

9305:MFSD4A
gene id: 9305:MFSD4A
uniprot id: G3WRX5
names: Subcellular Location Annotation
messages: Membrane

9305:YKT6
gene id: 9305:YKT6
uniprot id: G3WQE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

9305:XPO5
gene id: 9305:XPO5
uniprot id: A0A7N4V720
names: Subcellular Location Annotation
messages: Cytoplasm

9305:FAM229B
gene id: 9305:FAM229B
uniprot id: G3WM14
names: Similarity
messages: Belongs to the FAM229 family.

9305:LOC100916148
gene id: 9305:LOC100916148
uniprot id: A0A7N4NHJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100918225
gene id: 9305:LOC100918225
uniprot id: A0A7N4PX49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:COPS4
gene id: 9305:COPS4
uniprot id: G3W0X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

9305:RPL23
gene id: 9305:RPL23
uniprot id: G3WXX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

9305:PPIC
gene id: 9305:PPIC
uniprot id: G3WBX0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9305:NLGN2
gene id: 9305:NLGN2
uniprot id: G3VSL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

9305:OLAH
gene id: 9305:OLAH
uniprot id: G3WSI7
names: Similarity
messages: Belongs to the thioesterase family.

9305:LPO
gene id: 9305:LPO
uniprot id: G3WEN8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Secreted

9305:PEX2
gene id: 9305:PEX2
uniprot id: G3WJD1
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

9305:LOC100930022
gene id: 9305:LOC100930022
uniprot id: G3WQ51
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

9305:CMPK1
gene id: 9305:CMPK1
uniprot id: G3W7E8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

9305:GOT1L1
gene id: 9305:GOT1L1
uniprot id: A0A7N4Q086
uniprot id: G3WWR3
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

9305:ND2
gene id: 9305:ND2
uniprot id: G8XYV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

9305:MC2R
gene id: 9305:MC2R
uniprot id: G3WTM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane

9305:NEUROD4
gene id: 9305:NEUROD4
uniprot id: G3W2H3
names: Subcellular Location Annotation
messages: Nucleus

9305:OGFRL1
gene id: 9305:OGFRL1
uniprot id: G3WV34
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

9305:WNT6
gene id: 9305:WNT6
uniprot id: A0A7N4PZB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9305:NECAP1
gene id: 9305:NECAP1
uniprot id: G3WXE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

9305:SLC18B1
gene id: 9305:SLC18B1
uniprot id: G3W2Z7
names: Subcellular Location Annotation
messages: Membrane

9305:LOC100922750
gene id: 9305:LOC100922750
uniprot id: A0A7N4V543
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:TIMELESS
gene id: 9305:TIMELESS
uniprot id: G3VBC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Nucleus

9305:FAM187B
gene id: 9305:FAM187B
uniprot id: G3VIT2
names: Subcellular Location Annotation
messages: Membrane

9305:TAT
gene id: 9305:TAT
uniprot id: G3VQD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

9305:MAPRE2
gene id: 9305:MAPRE2
uniprot id: G3W6C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
messages: cytoskeleton

9305:ZFP36L1
gene id: 9305:ZFP36L1
uniprot id: A0A7N4PQX2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

9305:GTPBP4
gene id: 9305:GTPBP4
uniprot id: G3WPF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

9305:NPC1L1
gene id: 9305:NPC1L1
uniprot id: G3WVB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

9305:LOC100930724
gene id: 9305:LOC100930724
uniprot id: G3VMZ7
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

9305:TM4SF18
gene id: 9305:TM4SF18
uniprot id: A0A7N4PNR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9305:LOC100931615
gene id: 9305:LOC100931615
uniprot id: A0A7N4NXD3
names: Similarity
messages: Belongs to the MS4A family.

9305:MED30
gene id: 9305:MED30
uniprot id: G3VQQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

9305:MS4A3
gene id: 9305:MS4A3
uniprot id: A0A7N4P056
names: Similarity
messages: Belongs to the MS4A family.

9305:LOC100929654
gene id: 9305:LOC100929654
uniprot id: G3WIX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:NIBAN3
gene id: 9305:NIBAN3
uniprot id: G3WF79
names: Similarity
messages: Belongs to the Niban family.

9305:LOC100913340
gene id: 9305:LOC100913340
uniprot id: A0A7N4PA62
names: Similarity
messages: Belongs to the fructosamine kinase family.

9305:SPIN1
gene id: 9305:SPIN1
uniprot id: A0A7N4V7Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

9305:GRPR
gene id: 9305:GRPR
uniprot id: A0A7N4P155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:LOC100916971
gene id: 9305:LOC100916971
uniprot id: G3VNK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9305:SOX14
gene id: 9305:SOX14
uniprot id: A0A7N4NK23
names: Subcellular Location Annotation
messages: Nucleus

9305:TSC22D4
gene id: 9305:TSC22D4
uniprot id: A0A7N4NPT4
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

9305:AIF1L
gene id: 9305:AIF1L
uniprot id: A0A7N4P064
names: Subcellular Location Annotation
messages: ruffle membrane

9305:VTI1B
gene id: 9305:VTI1B
uniprot id: G3WFG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

9305:NEUROD1
gene id: 9305:NEUROD1
uniprot id: A0A7N4UXL1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9305:RALB
gene id: 9305:RALB
uniprot id: G3WHN5
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

9305:GLS2
gene id: 9305:GLS2
uniprot id: A0A7N4PJ20
uniprot id: G3VLF7
names: Similarity
messages: Belongs to the glutaminase family.

9305:ELF2
gene id: 9305:ELF2
uniprot id: G3VIM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9305:MPZ
gene id: 9305:MPZ
uniprot id: A0A7N4NN84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the myelin P0 protein family.
messages: Cell membrane
messages: Homodimer and homotetramer.
messages: Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.
messages: Membrane

9305:LOC100915970
gene id: 9305:LOC100915970
uniprot id: G3X2Z0
names: Similarity
messages: Belongs to the cytochrome P450 family.

9305:ANXA6
gene id: 9305:ANXA6
uniprot id: A0A7N4P1R5
uniprot id: A0A7N4PPX1
uniprot id: G3VF53
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome