927083:DB32 RS34620
gene id: 927083:DB32_RS34620
uniprot id: A0A0F6W895
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS38155
gene id: 927083:DB32_RS38155
uniprot id: A0A0F6W948
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

927083:DB32 RS09215
gene id: 927083:DB32_RS09215
uniprot id: A0A0F6W108
names: Subcellular Location Annotation
messages: Nucleus

927083:DB32 RS27665
gene id: 927083:DB32_RS27665
uniprot id: A0A0F6YK59
names: Similarity
messages: Belongs to the universal stress protein A family.

927083:DB32 RS19380
gene id: 927083:DB32_RS19380
uniprot id: A0A0F6YJ13
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

927083:DB32 RS12645
gene id: 927083:DB32_RS12645
uniprot id: A0A0F6YH82
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS38215
gene id: 927083:DB32_RS38215
uniprot id: A0A0F6W954
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

927083:DB32 RS30765
gene id: 927083:DB32_RS30765
uniprot id: A0A0F6W716
names: Similarity
messages: Belongs to the Lgt family.

927083:DB32 RS40380
gene id: 927083:DB32_RS40380
uniprot id: A0A0F6YN90
names: Similarity
messages: Belongs to the heat shock protein 70 family.

927083:DB32 RS01460
gene id: 927083:DB32_RS01460
uniprot id: A0A0F6VYV5
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

927083:DB32 RS09770
gene id: 927083:DB32_RS09770
uniprot id: A0A0F6SEA5
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS01645
gene id: 927083:DB32_RS01645
uniprot id: A0A0F6VYX7
names: Similarity
messages: Belongs to the NodU/CmcH family.

927083:DB32 RS07645
gene id: 927083:DB32_RS07645
uniprot id: A0A0F6W0W8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

927083:DB32 RS17650
gene id: 927083:DB32_RS17650
uniprot id: A0A0F6YI89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

927083:DB32 RS12955
gene id: 927083:DB32_RS12955
uniprot id: A0A0F6YHC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

927083:DB32 RS09530
gene id: 927083:DB32_RS09530
uniprot id: A0A0F6SE95
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

927083:DB32 RS22390
gene id: 927083:DB32_RS22390
uniprot id: A0A0F6YIW0
names: Subcellular Location Annotation
messages: Cell outer membrane

927083:DB32 RS18240
gene id: 927083:DB32_RS18240
uniprot id: A0A0F6W3N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

927083:DB32 RS03295
gene id: 927083:DB32_RS03295
uniprot id: A0A0F6VZK7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

927083:DB32 RS19745
gene id: 927083:DB32_RS19745
uniprot id: A0A0F6W427
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

927083:DB32 RS12980
gene id: 927083:DB32_RS12980
uniprot id: A0A0F6YHU6
names: Subunit
messages: Heterodimer of a large and a small subunit.

927083:DB32 RS15170
gene id: 927083:DB32_RS15170
uniprot id: A0A0F6YHQ3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

927083:DB32 RS40850
gene id: 927083:DB32_RS40850
uniprot id: A0A0F6SHX2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

927083:DB32 RS49580
gene id: 927083:DB32_RS49580
uniprot id: A0A0F6YIG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

927083:DB32 RS08785
gene id: 927083:DB32_RS08785
uniprot id: A0A0F6SE64
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

927083:DB32 RS36910
gene id: 927083:DB32_RS36910
uniprot id: A0A0F6SHG0
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS17810
gene id: 927083:DB32_RS17810
uniprot id: A0A0F6W3E9
names: Similarity
messages: Belongs to the AlaDH/PNT family.

927083:DB32 RS12730
gene id: 927083:DB32_RS12730
uniprot id: A0A0F6W217
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

927083:DB32 RS37160
gene id: 927083:DB32_RS37160
uniprot id: A0A0F6SHH0
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

927083:DB32 RS42420
gene id: 927083:DB32_RS42420
uniprot id: A0A0F6YMW0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

927083:DB32 RS29155
gene id: 927083:DB32_RS29155
uniprot id: A0A0F6SGJ7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

927083:DB32 RS19275
gene id: 927083:DB32_RS19275
uniprot id: A0A0F6SFE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

927083:DB32 RS18370
gene id: 927083:DB32_RS18370
uniprot id: A0A0F6W3K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

927083:DB32 RS08550
gene id: 927083:DB32_RS08550
uniprot id: A0A0F6W0T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

927083:DB32 RS48635
gene id: 927083:DB32_RS48635
uniprot id: A0A0F6SGM4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

927083:DB32 RS17485
gene id: 927083:DB32_RS17485
uniprot id: A0A0F6YJR9
names: Similarity
messages: Belongs to the peptidase S13 family.

927083:DB32 RS14640
gene id: 927083:DB32_RS14640
uniprot id: A0A0F6SEV5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

927083:DB32 RS08185
gene id: 927083:DB32_RS08185
uniprot id: A0A0F6W0T0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS23990
gene id: 927083:DB32_RS23990
uniprot id: A0A0F6SFY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

927083:DB32 RS27625
gene id: 927083:DB32_RS27625
uniprot id: A0A0F6SGD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

927083:DB32 RS15155
gene id: 927083:DB32_RS15155
uniprot id: A0A0F6YJ94
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

927083:DB32 RS19525
gene id: 927083:DB32_RS19525
uniprot id: A0A0F6YJ21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

927083:DB32 RS34605
gene id: 927083:DB32_RS34605
uniprot id: A0A0F6W8E1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

927083:DB32 RS23540
gene id: 927083:DB32_RS23540
uniprot id: A0A0F6YJ65
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

927083:DB32 RS13580
gene id: 927083:DB32_RS13580
uniprot id: A0A0F6W2B6
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

927083:DB32 RS16655
gene id: 927083:DB32_RS16655
uniprot id: A0A0F6YI25
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

927083:DB32 RS01195
gene id: 927083:DB32_RS01195
uniprot id: A0A0F6VYT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

927083:DB32 RS05295
gene id: 927083:DB32_RS05295
uniprot id: A0A0F6VZX5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

927083:DB32 RS20795
gene id: 927083:DB32_RS20795
uniprot id: A0A0F6W492
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS30495
gene id: 927083:DB32_RS30495
uniprot id: A0A0F6YM64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

927083:DB32 RS38805
gene id: 927083:DB32_RS38805
uniprot id: A0A0F6W9E7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

927083:DB32 RS29250
gene id: 927083:DB32_RS29250
uniprot id: A0A0F6W6X9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

927083:DB32 RS35575
gene id: 927083:DB32_RS35575
uniprot id: A0A0F6SHA8
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS30500
gene id: 927083:DB32_RS30500
uniprot id: A0A0F6W782
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

927083:DB32 RS32730
gene id: 927083:DB32_RS32730
uniprot id: A0A0F6W7Q1
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS14990
gene id: 927083:DB32_RS14990
uniprot id: A0A0F6SEW9
names: Similarity
messages: Belongs to the SUI1 family.

927083:DB32 RS28915
gene id: 927083:DB32_RS28915
uniprot id: A0A0F6SGI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

927083:DB32 RS40185
gene id: 927083:DB32_RS40185
uniprot id: A0A0F6YM72
names: Similarity
messages: Belongs to the GSP E family.

927083:DB32 RS27470
gene id: 927083:DB32_RS27470
uniprot id: A0A0F6YKJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

927083:DB32 RS18160
gene id: 927083:DB32_RS18160
uniprot id: A0A0F6W3I5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS08080
gene id: 927083:DB32_RS08080
uniprot id: A0A0F6YGB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS24960
gene id: 927083:DB32_RS24960
uniprot id: A0A0F6YK52
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

927083:DB32 RS04900
gene id: 927083:DB32_RS04900
uniprot id: A0A0F6VZT6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

927083:DB32 RS31870
gene id: 927083:DB32_RS31870
uniprot id: A0A0F6W7C9
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

927083:DB32 RS14585
gene id: 927083:DB32_RS14585
uniprot id: A0A0F6W2I5
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

927083:DB32 RS30810
gene id: 927083:DB32_RS30810
uniprot id: A0A0F6W753
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS11015
gene id: 927083:DB32_RS11015
uniprot id: A0A0F6SEF6
names: Similarity
messages: Belongs to the YkuD family.

927083:DB32 RS16250
gene id: 927083:DB32_RS16250
uniprot id: A0A0F6W334
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

927083:DB32 RS17200
gene id: 927083:DB32_RS17200
uniprot id: A0A0F6W3C6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

927083:DB32 RS23090
gene id: 927083:DB32_RS23090
uniprot id: A0A0F6W4Z4
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

927083:DB32 RS43070
gene id: 927083:DB32_RS43070
uniprot id: A0A0F6WAM6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

927083:DB32 RS05140
gene id: 927083:DB32_RS05140
uniprot id: A0A0F6VZW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

927083:DB32 RS36310
gene id: 927083:DB32_RS36310
uniprot id: A0A0F6W8T5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

927083:DB32 RS06775
gene id: 927083:DB32_RS06775
uniprot id: A0A0F6SDY2
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS32585
gene id: 927083:DB32_RS32585
uniprot id: A0A0F6YMP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

927083:DB32 RS32565
gene id: 927083:DB32_RS32565
uniprot id: A0A0F6YKS4
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS28010
gene id: 927083:DB32_RS28010
uniprot id: A0A0F6W6L1
names: Similarity
messages: Belongs to the disproportionating enzyme family.

927083:DB32 RS31860
gene id: 927083:DB32_RS31860
uniprot id: A0A0F6YL22
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS14985
gene id: 927083:DB32_RS14985
uniprot id: A0A0F6W2Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

927083:DB32 RS35925
gene id: 927083:DB32_RS35925
uniprot id: A0A0F6SHC2
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

927083:DB32 RS10405
gene id: 927083:DB32_RS10405
uniprot id: A0A0F6W1N9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS32125
gene id: 927083:DB32_RS32125
uniprot id: A0A0F6YLG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

927083:DB32 RS11430
gene id: 927083:DB32_RS11430
uniprot id: A0A0F6W1M0
names: Similarity
messages: Belongs to the peptidase M24B family.

927083:DB32 RS04985
gene id: 927083:DB32_RS04985
uniprot id: A0A0F6VZV2
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

927083:DB32 RS41470
gene id: 927083:DB32_RS41470
uniprot id: A0A0F6WA84
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

927083:DB32 RS18005
gene id: 927083:DB32_RS18005
uniprot id: A0A0F6YI30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

927083:DB32 RS14405
gene id: 927083:DB32_RS14405
uniprot id: A0A0F6W2J5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS25480
gene id: 927083:DB32_RS25480
uniprot id: A0A0F6W5K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

927083:DB32 RS47750
gene id: 927083:DB32_RS47750
uniprot id: A0A0F6WAB3
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

927083:DB32 RS30190
gene id: 927083:DB32_RS30190
uniprot id: A0A0F6SGN9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

927083:DB32 RS06240
gene id: 927083:DB32_RS06240
uniprot id: A0A0F6YGM7
names: Similarity
messages: Belongs to the YciI family.

927083:DB32 RS36840
gene id: 927083:DB32_RS36840
uniprot id: A0A0F6W8X3
names: Similarity
messages: Belongs to the YciI family.

927083:DB32 RS16970
gene id: 927083:DB32_RS16970
uniprot id: A0A0F6W366
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane
messages: Cytoplasm

927083:DB32 RS15485
gene id: 927083:DB32_RS15485
uniprot id: A0A0F6W2V1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

927083:DB32 RS25655
gene id: 927083:DB32_RS25655
uniprot id: A0A0F6YK96
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

927083:DB32 RS33890
gene id: 927083:DB32_RS33890
uniprot id: A0A0F6W7Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS18410
gene id: 927083:DB32_RS18410
uniprot id: A0A0F6SFA7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

927083:DB32 RS09320
gene id: 927083:DB32_RS09320
uniprot id: A0A0F6SE86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

927083:DB32 RS19060
gene id: 927083:DB32_RS19060
uniprot id: A0A0F6W421
names: Subcellular Location Annotation
messages: Nucleus

927083:DB32 RS41395
gene id: 927083:DB32_RS41395
uniprot id: A0A0F6WA32
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

927083:DB32 RS05845
gene id: 927083:DB32_RS05845
uniprot id: A0A0F6W0B7
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS30700
gene id: 927083:DB32_RS30700
uniprot id: A0A0F6W743
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

927083:DB32 RS39240
gene id: 927083:DB32_RS39240
uniprot id: A0A0F6W9G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

927083:DB32 RS29685
gene id: 927083:DB32_RS29685
uniprot id: A0A0F6W721
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS27750
gene id: 927083:DB32_RS27750
uniprot id: A0A0F6W675
names: Similarity
messages: Belongs to the peptidase M16 family.

927083:DB32 RS04525
gene id: 927083:DB32_RS04525
uniprot id: A0A0F6SDN7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

927083:DB32 RS17955
gene id: 927083:DB32_RS17955
uniprot id: A0A0F6YIA9
names: Similarity
messages: Belongs to the CutA family.

927083:DB32 RS40505
gene id: 927083:DB32_RS40505
uniprot id: A0A0F6SHV7
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

927083:DB32 RS15520
gene id: 927083:DB32_RS15520
uniprot id: A0A0F6W2V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

927083:DB32 RS16170
gene id: 927083:DB32_RS16170
uniprot id: A0A0F6YHY0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

927083:DB32 RS17960
gene id: 927083:DB32_RS17960
uniprot id: A0A0F6W3K6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS19140
gene id: 927083:DB32_RS19140
uniprot id: A0A0F6W3T9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

927083:DB32 RS40625
gene id: 927083:DB32_RS40625
uniprot id: A0A0F6W9Z9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

927083:DB32 RS12415
gene id: 927083:DB32_RS12415
uniprot id: A0A0F6YH68
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

927083:DB32 RS00245
gene id: 927083:DB32_RS00245
uniprot id: A0A0F6SD64
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

927083:DB32 RS12760
gene id: 927083:DB32_RS12760
uniprot id: A0A0F6W219
names: Similarity
messages: Belongs to the band 7/mec-2 family.

927083:DB32 RS11565
gene id: 927083:DB32_RS11565
uniprot id: A0A0F6YGY5
names: Similarity
messages: Belongs to the peptidase A24 family.

927083:DB32 RS37930
gene id: 927083:DB32_RS37930
uniprot id: A0A0F6YM30
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

927083:DB32 RS17935
gene id: 927083:DB32_RS17935
uniprot id: A0A0F6W3G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

927083:DB32 RS01210
gene id: 927083:DB32_RS01210
uniprot id: A0A0F6VZ24
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS12735
gene id: 927083:DB32_RS12735
uniprot id: A0A0F6YI31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

927083:DB32 RS38750
gene id: 927083:DB32_RS38750
uniprot id: A0A0F6W9A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

927083:DB32 RS21885
gene id: 927083:DB32_RS21885
uniprot id: A0A0F6W4V1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

927083:DB32 RS23085
gene id: 927083:DB32_RS23085
uniprot id: A0A0F6YJT3
names: Similarity
messages: Belongs to the HesB/IscA family.

927083:DB32 RS31285
gene id: 927083:DB32_RS31285
uniprot id: A0A0F6SGT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

927083:DB32 RS34965
gene id: 927083:DB32_RS34965
uniprot id: A0A0F6W887
names: Similarity
messages: Belongs to the peptidase S33 family.

927083:DB32 RS08480
gene id: 927083:DB32_RS08480
uniprot id: A0A0F6SE51
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

927083:DB32 RS32865
gene id: 927083:DB32_RS32865
uniprot id: A0A0F6W7M6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS00550
gene id: 927083:DB32_RS00550
uniprot id: A0A0F6VYN0
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS27605
gene id: 927083:DB32_RS27605
uniprot id: A0A0F6YKS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

927083:DB32 RS29260
gene id: 927083:DB32_RS29260
uniprot id: A0A0F6YKF9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

927083:DB32 RS28515
gene id: 927083:DB32_RS28515
uniprot id: A0A0F6W6R2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

927083:DB32 RS17095
gene id: 927083:DB32_RS17095
uniprot id: A0A0F6YHY1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

927083:DB32 RS11275
gene id: 927083:DB32_RS11275
uniprot id: A0A0F6W1N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

927083:DB32 RS25625
gene id: 927083:DB32_RS25625
uniprot id: A0A0F6YKG2
names: Similarity
messages: Belongs to the AHA1 family.

927083:DB32 RS16010
gene id: 927083:DB32_RS16010
uniprot id: A0A0F6W2Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

927083:DB32 RS17575
gene id: 927083:DB32_RS17575
uniprot id: A0A0F6YI85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

927083:DB32 RS11505
gene id: 927083:DB32_RS11505
uniprot id: A0A0F6W1Y7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

927083:DB32 RS43190
gene id: 927083:DB32_RS43190
uniprot id: A0A0F6SI67
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS14220
gene id: 927083:DB32_RS14220
uniprot id: A0A0F6W2H8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

927083:DB32 RS34725
gene id: 927083:DB32_RS34725
uniprot id: A0A0F6YN36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS33650
gene id: 927083:DB32_RS33650
uniprot id: A0A0F6YKZ1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

927083:DB32 RS05325
gene id: 927083:DB32_RS05325
uniprot id: A0A0F6YGQ0
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

927083:DB32 RS17420
gene id: 927083:DB32_RS17420
uniprot id: A0A0F6W3F1
names: Similarity
messages: Belongs to the cytochrome c-552 family.

927083:DB32 RS17995
gene id: 927083:DB32_RS17995
uniprot id: A0A0F6W3L0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

927083:DB32 RS38395
gene id: 927083:DB32_RS38395
uniprot id: A0A0F6SHL9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

927083:DB32 RS23295
gene id: 927083:DB32_RS23295
uniprot id: A0A0F6W515
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

927083:DB32 RS43760
gene id: 927083:DB32_RS43760
uniprot id: A0A0F6YMV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

927083:DB32 RS12935
gene id: 927083:DB32_RS12935
uniprot id: A0A0F6YIU7
names: Similarity
messages: Belongs to the WrbA family.

927083:DB32 RS21840
gene id: 927083:DB32_RS21840
uniprot id: A0A0F6W4N9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

927083:DB32 RS41065
gene id: 927083:DB32_RS41065
uniprot id: A0A0F6YMW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

927083:DB32 RS11035
gene id: 927083:DB32_RS11035
uniprot id: A0A0F6YIG9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

927083:DB32 RS23400
gene id: 927083:DB32_RS23400
uniprot id: A0A0F6YKU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

927083:DB32 RS44345
gene id: 927083:DB32_RS44345
uniprot id: A0A0F6SFH7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

927083:DB32 RS02985
gene id: 927083:DB32_RS02985
uniprot id: A0A0F6VZA7
names: Similarity
messages: Belongs to the archease family.

927083:DB32 RS13240
gene id: 927083:DB32_RS13240
uniprot id: A0A0F6W259
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

927083:DB32 RS05335
gene id: 927083:DB32_RS05335
uniprot id: A0A0F6SDS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

927083:DB32 RS15265
gene id: 927083:DB32_RS15265
uniprot id: A0A0F6YIJ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

927083:DB32 RS32320
gene id: 927083:DB32_RS32320
uniprot id: A0A0F6W7H0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS14090
gene id: 927083:DB32_RS14090
uniprot id: A0A0F6W2P5
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

927083:DB32 RS38650
gene id: 927083:DB32_RS38650
uniprot id: A0A0F6W9F1
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS03095
gene id: 927083:DB32_RS03095
uniprot id: A0A0F6SDH7
names: Similarity
messages: Belongs to the creatininase superfamily.

927083:DB32 RS29220
gene id: 927083:DB32_RS29220
uniprot id: A0A0F6W6X6
names: Similarity
messages: Belongs to the VgrG protein family.

927083:DB32 RS04150
gene id: 927083:DB32_RS04150
uniprot id: A0A0F6SDM1
names: Similarity
messages: Belongs to the UPF0234 family.

927083:DB32 RS25275
gene id: 927083:DB32_RS25275
uniprot id: A0A0F6YJF4
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

927083:DB32 RS06810
gene id: 927083:DB32_RS06810
uniprot id: A0A0F6W0P0
names: Similarity
messages: Belongs to the YciI family.

927083:DB32 RS08905
gene id: 927083:DB32_RS08905
uniprot id: A0A0F6W103
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

927083:DB32 RS06570
gene id: 927083:DB32_RS06570
uniprot id: A0A0F6SDX3
names: Subcellular Location Annotation
messages: nucleolus

927083:DB32 RS12070
gene id: 927083:DB32_RS12070
uniprot id: A0A0F6YHQ5
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

927083:DB32 RS38940
gene id: 927083:DB32_RS38940
uniprot id: A0A0F6YN25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

927083:DB32 RS21545
gene id: 927083:DB32_RS21545
uniprot id: A0A0F6YKG7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

927083:DB32 RS21420
gene id: 927083:DB32_RS21420
uniprot id: A0A0F6W4N1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

927083:DB32 RS06610
gene id: 927083:DB32_RS06610
uniprot id: A0A0F6YG09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

927083:DB32 RS31895
gene id: 927083:DB32_RS31895
uniprot id: A0A0F6W7G5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

927083:DB32 RS21475
gene id: 927083:DB32_RS21475
uniprot id: A0A0F6YKG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

927083:DB32 RS23145
gene id: 927083:DB32_RS23145
uniprot id: A0A0F6W500
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

927083:DB32 RS15990
gene id: 927083:DB32_RS15990
uniprot id: A0A0F6W379
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

927083:DB32 RS31790
gene id: 927083:DB32_RS31790
uniprot id: A0A0F6YLM3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

927083:DB32 RS09270
gene id: 927083:DB32_RS09270
uniprot id: A0A0F6W138
names: Subunit
messages: Heterodimer of a large and a small subunit.

927083:DB32 RS23130
gene id: 927083:DB32_RS23130
uniprot id: A0A0F6YJA2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

927083:DB32 RS42840
gene id: 927083:DB32_RS42840
uniprot id: A0A0F6SI53
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS38420
gene id: 927083:DB32_RS38420
uniprot id: A0A0F6SHM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.

927083:DB32 RS22610
gene id: 927083:DB32_RS22610
uniprot id: A0A0F6SFS7
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

927083:DB32 RS10215
gene id: 927083:DB32_RS10215
uniprot id: A0A0F6SEC3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

927083:DB32 RS23080
gene id: 927083:DB32_RS23080
uniprot id: A0A0F6SFU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

927083:DB32 RS27525
gene id: 927083:DB32_RS27525
uniprot id: A0A0F6W6D8
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS05275
gene id: 927083:DB32_RS05275
uniprot id: A0A0F6W075
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

927083:DB32 RS17655
gene id: 927083:DB32_RS17655
uniprot id: A0A0F6W3H5
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS26010
gene id: 927083:DB32_RS26010
uniprot id: A0A0F6SG67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

927083:DB32 RS32535
gene id: 927083:DB32_RS32535
uniprot id: A0A0F6YL62
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS01440
gene id: 927083:DB32_RS01440
uniprot id: A0A0F6VZ46
names: Similarity
messages: Belongs to the AHA1 family.

927083:DB32 RS18715
gene id: 927083:DB32_RS18715
uniprot id: A0A0F6W3Q9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS25920
gene id: 927083:DB32_RS25920
uniprot id: A0A0F6W5Z8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

927083:DB32 RS38435
gene id: 927083:DB32_RS38435
uniprot id: A0A0F6W9D3
names: Similarity
messages: Belongs to the SCO1/2 family.

927083:DB32 RS15345
gene id: 927083:DB32_RS15345
uniprot id: A0A0F6SEY3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS42805
gene id: 927083:DB32_RS42805
uniprot id: A0A0F6YNK3
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

927083:DB32 RS17220
gene id: 927083:DB32_RS17220
uniprot id: A0A0F6W3I4
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

927083:DB32 RS26645
gene id: 927083:DB32_RS26645
uniprot id: A0A0F6YJP6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

927083:DB32 RS01720
gene id: 927083:DB32_RS01720
uniprot id: A0A0F6VZ74
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

927083:DB32 RS33665
gene id: 927083:DB32_RS33665
uniprot id: A0A0F6YMX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

927083:DB32 RS43875
gene id: 927083:DB32_RS43875
uniprot id: A0A0F6WAS1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS38890
gene id: 927083:DB32_RS38890
uniprot id: A0A0F6SHP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

927083:DB32 RS38640
gene id: 927083:DB32_RS38640
uniprot id: A0A0F6W995
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

927083:DB32 RS28775
gene id: 927083:DB32_RS28775
uniprot id: A0A0F6W6L0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

927083:DB32 RS13705
gene id: 927083:DB32_RS13705
uniprot id: A0A0F6W297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

927083:DB32 RS21725
gene id: 927083:DB32_RS21725
uniprot id: A0A0F6YIZ1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

927083:DB32 RS05595
gene id: 927083:DB32_RS05595
uniprot id: A0A0F6SDT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

927083:DB32 RS25485
gene id: 927083:DB32_RS25485
uniprot id: A0A0F6YKF3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

927083:DB32 RS43705
gene id: 927083:DB32_RS43705
uniprot id: A0A0F6WAV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the PduL family.
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

927083:DB32 RS09510
gene id: 927083:DB32_RS09510
uniprot id: A0A0F6SE94
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

927083:DB32 RS20700
gene id: 927083:DB32_RS20700
uniprot id: A0A0F6W483
names: Similarity
messages: Belongs to the YkuD family.

927083:DB32 RS03745
gene id: 927083:DB32_RS03745
uniprot id: A0A0F6SDK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

927083:DB32 RS41995
gene id: 927083:DB32_RS41995
uniprot id: A0A0F6WAD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

927083:DB32 RS21160
gene id: 927083:DB32_RS21160
uniprot id: A0A0F6W4G4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

927083:DB32 RS25505
gene id: 927083:DB32_RS25505
uniprot id: A0A0F6W5N6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS48265
gene id: 927083:DB32_RS48265
uniprot id: A0A0F6W3A6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

927083:DB32 RS18365
gene id: 927083:DB32_RS18365
uniprot id: A0A0F6W3P2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

927083:DB32 RS07925
gene id: 927083:DB32_RS07925
uniprot id: A0A0F6YGA9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

927083:DB32 RS39395
gene id: 927083:DB32_RS39395
uniprot id: A0A0F6YN51
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS23070
gene id: 927083:DB32_RS23070
uniprot id: A0A0F6YK06
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

927083:DB32 RS24270
gene id: 927083:DB32_RS24270
uniprot id: A0A0F6YJG8
names: Similarity
messages: Belongs to the thioredoxin family.

927083:DB32 RS38035
gene id: 927083:DB32_RS38035
uniprot id: A0A0F6YMC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

927083:DB32 RS08810
gene id: 927083:DB32_RS08810
uniprot id: A0A0F6SE65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

927083:DB32 RS16520
gene id: 927083:DB32_RS16520
uniprot id: A0A0F6W327
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

927083:DB32 RS24385
gene id: 927083:DB32_RS24385
uniprot id: A0A0F6YJA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS12175
gene id: 927083:DB32_RS12175
uniprot id: A0A0F6W1Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

927083:DB32 RS36095
gene id: 927083:DB32_RS36095
uniprot id: A0A0F6SHC9
names: Similarity
messages: Belongs to the AdoMet synthase family.

927083:DB32 RS35595
gene id: 927083:DB32_RS35595
uniprot id: A0A0F6W8I7
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

927083:DB32 RS18910
gene id: 927083:DB32_RS18910
uniprot id: A0A0F6W406
names: Similarity
messages: Belongs to the UDPGP type 1 family.

927083:DB32 RS12010
gene id: 927083:DB32_RS12010
uniprot id: A0A0F6W1T2
names: Similarity
messages: Belongs to the PspA/IM30 family.

927083:DB32 RS38055
gene id: 927083:DB32_RS38055
uniprot id: A0A0F6W973
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

927083:DB32 RS11640
gene id: 927083:DB32_RS11640
uniprot id: A0A0F6W1S5
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

927083:DB32 RS33210
gene id: 927083:DB32_RS33210
uniprot id: A0A0F6W7U8
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS31995
gene id: 927083:DB32_RS31995
uniprot id: A0A0F6SGW3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

927083:DB32 RS04135
gene id: 927083:DB32_RS04135
uniprot id: A0A0F6VZL4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

927083:DB32 RS20235
gene id: 927083:DB32_RS20235
uniprot id: A0A0F6YIF8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

927083:DB32 RS42550
gene id: 927083:DB32_RS42550
uniprot id: A0A0F6SI41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

927083:DB32 RS05450
gene id: 927083:DB32_RS05450
uniprot id: A0A0F6W091
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

927083:DB32 RS37505
gene id: 927083:DB32_RS37505
uniprot id: A0A0F6SHI4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

927083:DB32 RS42085
gene id: 927083:DB32_RS42085
uniprot id: A0A0F6SI22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

927083:DB32 RS37955
gene id: 927083:DB32_RS37955
uniprot id: A0A0F6YMC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

927083:DB32 RS31475
gene id: 927083:DB32_RS31475
uniprot id: A0A0F6W7D0
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

927083:DB32 RS13105
gene id: 927083:DB32_RS13105
uniprot id: A0A0F6SEP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

927083:DB32 RS32570
gene id: 927083:DB32_RS32570
uniprot id: A0A0F6W7N5
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

927083:DB32 RS21440
gene id: 927083:DB32_RS21440
uniprot id: A0A0F6W4F7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

927083:DB32 RS37150
gene id: 927083:DB32_RS37150
uniprot id: A0A0F6W918
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS38230
gene id: 927083:DB32_RS38230
uniprot id: A0A0F6W9B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

927083:DB32 RS41280
gene id: 927083:DB32_RS41280
uniprot id: A0A0F6WA66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

927083:DB32 RS38430
gene id: 927083:DB32_RS38430
uniprot id: A0A0F6YMY4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

927083:DB32 RS18255
gene id: 927083:DB32_RS18255
uniprot id: A0A0F6W3S3
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

927083:DB32 RS23255
gene id: 927083:DB32_RS23255
uniprot id: A0A0F6YKT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

927083:DB32 RS28130
gene id: 927083:DB32_RS28130
uniprot id: A0A0F6W6M3
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

927083:DB32 RS36315
gene id: 927083:DB32_RS36315
uniprot id: A0A0F6SHD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

927083:DB32 RS29710
gene id: 927083:DB32_RS29710
uniprot id: A0A0F6YM15
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS24125
gene id: 927083:DB32_RS24125
uniprot id: A0A0F6W5F6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

927083:DB32 RS08160
gene id: 927083:DB32_RS08160
uniprot id: A0A0F6W0S7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

927083:DB32 RS27215
gene id: 927083:DB32_RS27215
uniprot id: A0A0F6YK29
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

927083:DB32 RS24745
gene id: 927083:DB32_RS24745
uniprot id: A0A0F6YK39
names: Similarity
messages: Belongs to the transketolase family.

927083:DB32 RS21015
gene id: 927083:DB32_RS21015
uniprot id: A0A0F6W4F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

927083:DB32 RS15015
gene id: 927083:DB32_RS15015
uniprot id: A0A0F6SEX0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

927083:DB32 RS19290
gene id: 927083:DB32_RS19290
uniprot id: A0A0F6W3Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS34470
gene id: 927083:DB32_RS34470
uniprot id: A0A0F6SH65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

927083:DB32 RS31515
gene id: 927083:DB32_RS31515
uniprot id: A0A0F6W7K3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

927083:DB32 RS19470
gene id: 927083:DB32_RS19470
uniprot id: A0A0F6SFF0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

927083:DB32 RS13645
gene id: 927083:DB32_RS13645
uniprot id: A0A0F6W292
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

927083:DB32 RS28790
gene id: 927083:DB32_RS28790
uniprot id: A0A0F6SGI2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

927083:DB32 RS39160
gene id: 927083:DB32_RS39160
uniprot id: A0A0F6YMB8
names: Similarity
messages: Belongs to the Gfa family.

927083:DB32 RS09445
gene id: 927083:DB32_RS09445
uniprot id: A0A0F6YI76
names: Similarity
messages: Belongs to the peptidase M16 family.

927083:DB32 RS07980
gene id: 927083:DB32_RS07980
uniprot id: A0A0F6W0N0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS42100
gene id: 927083:DB32_RS42100
uniprot id: A0A0F6WAB5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

927083:DB32 RS38165
gene id: 927083:DB32_RS38165
uniprot id: A0A0F6W9B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

927083:DB32 RS09925
gene id: 927083:DB32_RS09925
uniprot id: A0A0F6YHN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

927083:DB32 RS42155
gene id: 927083:DB32_RS42155
uniprot id: A0A0F6YN28
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS04370
gene id: 927083:DB32_RS04370
uniprot id: A0A0F6YGB1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

927083:DB32 RS10090
gene id: 927083:DB32_RS10090
uniprot id: A0A0F6SEB8
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS23285
gene id: 927083:DB32_RS23285
uniprot id: A0A0F6YK23
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

927083:DB32 RS28725
gene id: 927083:DB32_RS28725
uniprot id: A0A0F6YKC8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

927083:DB32 RS24940
gene id: 927083:DB32_RS24940
uniprot id: A0A0F6YJL3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

927083:DB32 RS36200
gene id: 927083:DB32_RS36200
uniprot id: A0A0F6W8S9
names: Similarity
messages: Belongs to the peptidase S51 family.

927083:DB32 RS25310
gene id: 927083:DB32_RS25310
uniprot id: A0A0F6W5M4
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS38085
gene id: 927083:DB32_RS38085
uniprot id: A0A0F6W976
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

927083:DB32 RS29030
gene id: 927083:DB32_RS29030
uniprot id: A0A0F6SGJ2
names: Similarity
messages: Belongs to the universal stress protein A family.

927083:DB32 RS39245
gene id: 927083:DB32_RS39245
uniprot id: A0A0F6YMC3
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

927083:DB32 RS22920
gene id: 927083:DB32_RS22920
uniprot id: A0A0F6YJW8
names: Similarity
messages: Belongs to the porin LamB (TC 1.B.3) family.

927083:DB32 RS05315
gene id: 927083:DB32_RS05315
uniprot id: A0A0F6SDS0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

927083:DB32 RS21225
gene id: 927083:DB32_RS21225
uniprot id: A0A0F6W4D5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

927083:DB32 RS24750
gene id: 927083:DB32_RS24750
uniprot id: A0A0F6SG15
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS12740
gene id: 927083:DB32_RS12740
uniprot id: A0A0F6SEM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

927083:DB32 RS21765
gene id: 927083:DB32_RS21765
uniprot id: A0A0F6W4T9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS33475
gene id: 927083:DB32_RS33475
uniprot id: A0A0F6SH24
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

927083:DB32 RS03715
gene id: 927083:DB32_RS03715
uniprot id: A0A0F6VZJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

927083:DB32 RS19965
gene id: 927083:DB32_RS19965
uniprot id: A0A0F6W408
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

927083:DB32 RS17640
gene id: 927083:DB32_RS17640
uniprot id: A0A0F6W3M4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

927083:DB32 RS42375
gene id: 927083:DB32_RS42375
uniprot id: A0A0F6WAE1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

927083:DB32 RS43205
gene id: 927083:DB32_RS43205
uniprot id: A0A0F6WAM7
names: Similarity
messages: Belongs to the GSP E family.

927083:DB32 RS18875
gene id: 927083:DB32_RS18875
uniprot id: A0A0F6W403
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

927083:DB32 RS02350
gene id: 927083:DB32_RS02350
uniprot id: A0A0F6VZ47
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

927083:DB32 RS38115
gene id: 927083:DB32_RS38115
uniprot id: A0A0F6W979
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

927083:DB32 RS30955
gene id: 927083:DB32_RS30955
uniprot id: A0A0F6SGS0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS11930
gene id: 927083:DB32_RS11930
uniprot id: A0A0F6YH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

927083:DB32 RS41060
gene id: 927083:DB32_RS41060
uniprot id: A0A0F6W9Z8
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS36180
gene id: 927083:DB32_RS36180
uniprot id: A0A0F6W8P8
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS22030
gene id: 927083:DB32_RS22030
uniprot id: A0A0F6YJ11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

927083:DB32 RS11005
gene id: 927083:DB32_RS11005
uniprot id: A0A0F6YHG2
names: Subunit
messages: Homodimer.

927083:DB32 RS15435
gene id: 927083:DB32_RS15435
uniprot id: A0A0F6YIE5
names: Similarity
messages: Belongs to the RutC family.

927083:DB32 RS10320
gene id: 927083:DB32_RS10320
uniprot id: A0A0F6YHD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

927083:DB32 RS25335
gene id: 927083:DB32_RS25335
uniprot id: A0A0F6YK75
names: Similarity
messages: Belongs to the UPF0047 family.

927083:DB32 RS14850
gene id: 927083:DB32_RS14850
uniprot id: A0A0F6YHN3
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS28370
gene id: 927083:DB32_RS28370
uniprot id: A0A0F6W6P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

927083:DB32 RS22730
gene id: 927083:DB32_RS22730
uniprot id: A0A0F6W4S9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

927083:DB32 RS17670
gene id: 927083:DB32_RS17670
uniprot id: A0A0F6SF77
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS04170
gene id: 927083:DB32_RS04170
uniprot id: A0A0F6YFL0
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS11050
gene id: 927083:DB32_RS11050
uniprot id: A0A0F6YGV4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

927083:DB32 RS08215
gene id: 927083:DB32_RS08215
uniprot id: A0A0F6SE40
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS31340
gene id: 927083:DB32_RS31340
uniprot id: A0A0F6SGT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

927083:DB32 RS28875
gene id: 927083:DB32_RS28875
uniprot id: A0A0F6W6I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

927083:DB32 RS16020
gene id: 927083:DB32_RS16020
uniprot id: A0A0F6W382
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

927083:DB32 RS18375
gene id: 927083:DB32_RS18375
uniprot id: A0A0F6YIV4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

927083:DB32 RS33825
gene id: 927083:DB32_RS33825
uniprot id: A0A0F6W808
names: Subcellular Location Annotation
messages: Peroxisome

927083:DB32 RS13160
gene id: 927083:DB32_RS13160
uniprot id: A0A0F6W253
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

927083:DB32 RS41580
gene id: 927083:DB32_RS41580
uniprot id: A0A0F6WA50
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS01070
gene id: 927083:DB32_RS01070
uniprot id: A0A0F6VYS3
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

927083:DB32 RS19790
gene id: 927083:DB32_RS19790
uniprot id: A0A0F6YIN0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

927083:DB32 RS21915
gene id: 927083:DB32_RS21915
uniprot id: A0A0F6W4V3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

927083:DB32 RS22560
gene id: 927083:DB32_RS22560
uniprot id: A0A0F6W4U6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

927083:DB32 RS21865
gene id: 927083:DB32_RS21865
uniprot id: A0A0F6W4P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

927083:DB32 RS43450
gene id: 927083:DB32_RS43450
uniprot id: A0A0F6SI78
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS00485
gene id: 927083:DB32_RS00485
uniprot id: A0A0F6SD74
names: Similarity
messages: Belongs to the AHA1 family.

927083:DB32 RS29415
gene id: 927083:DB32_RS29415
uniprot id: A0A0F6W6Z4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

927083:DB32 RS37555
gene id: 927083:DB32_RS37555
uniprot id: A0A0F6W955
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS18760
gene id: 927083:DB32_RS18760
uniprot id: A0A0F6YIX7
names: Similarity
messages: Belongs to the Gfa family.

927083:DB32 RS32045
gene id: 927083:DB32_RS32045
uniprot id: A0A0F6SGW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

927083:DB32 RS18755
gene id: 927083:DB32_RS18755
uniprot id: A0A0F6SFC1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

927083:DB32 RS22545
gene id: 927083:DB32_RS22545
uniprot id: A0A0F6W512
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

927083:DB32 RS18765
gene id: 927083:DB32_RS18765
uniprot id: A0A0F6W3U2
names: Similarity
messages: Belongs to the Gfa family.

927083:DB32 RS00995
gene id: 927083:DB32_RS00995
uniprot id: A0A0F6YEZ8
names: Similarity
messages: Belongs to the TPP enzyme family.

927083:DB32 RS11485
gene id: 927083:DB32_RS11485
uniprot id: A0A0F6SEH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Cytoplasm
messages: Homodimer.

927083:DB32 RS13605
gene id: 927083:DB32_RS13605
uniprot id: A0A0F6YH95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

927083:DB32 RS03540
gene id: 927083:DB32_RS03540
uniprot id: A0A0F6VZG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

927083:DB32 RS47880
gene id: 927083:DB32_RS47880
uniprot id: A0A0F6VZB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

927083:DB32 RS27145
gene id: 927083:DB32_RS27145
uniprot id: A0A0F6SGB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

927083:DB32 RS23075
gene id: 927083:DB32_RS23075
uniprot id: A0A0F6W561
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

927083:DB32 RS26340
gene id: 927083:DB32_RS26340
uniprot id: A0A0F6W637
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

927083:DB32 RS08170
gene id: 927083:DB32_RS08170
uniprot id: A0A0F6SE38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

927083:DB32 RS05045
gene id: 927083:DB32_RS05045
uniprot id: A0A0F6SDQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS16600
gene id: 927083:DB32_RS16600
uniprot id: A0A0F6W3D2
names: Similarity
messages: Belongs to the CFA/CMAS family.

927083:DB32 RS23660
gene id: 927083:DB32_RS23660
uniprot id: A0A0F6W523
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

927083:DB32 RS28335
gene id: 927083:DB32_RS28335
uniprot id: A0A0F6YLU0
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS11790
gene id: 927083:DB32_RS11790
uniprot id: A0A0F6W1Q9
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

927083:DB32 RS15455
gene id: 927083:DB32_RS15455
uniprot id: A0A0F6W2U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

927083:DB32 RS08560
gene id: 927083:DB32_RS08560
uniprot id: A0A0F6W145
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

927083:DB32 RS26800
gene id: 927083:DB32_RS26800
uniprot id: A0A0F6SGA0
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS01215
gene id: 927083:DB32_RS01215
uniprot id: A0A0F6YGP7
names: Subcellular Location Annotation
messages: Secreted

927083:DB32 RS42520
gene id: 927083:DB32_RS42520
uniprot id: A0A0F6YN52
names: Similarity
messages: Belongs to the creatininase superfamily.

927083:DB32 RS18890
gene id: 927083:DB32_RS18890
uniprot id: A0A0F6W3V4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

927083:DB32 RS48875
gene id: 927083:DB32_RS48875
uniprot id: A0A0F6YPC7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS16385
gene id: 927083:DB32_RS16385
uniprot id: A0A0F6SF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

927083:DB32 RS16005
gene id: 927083:DB32_RS16005
uniprot id: A0A0F6W318
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

927083:DB32 RS46825
gene id: 927083:DB32_RS46825
uniprot id: A0A0F6W3K1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

927083:DB32 RS48455
gene id: 927083:DB32_RS48455
uniprot id: A0A0F6W539
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

927083:DB32 RS25515
gene id: 927083:DB32_RS25515
uniprot id: A0A0F6YJH1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

927083:DB32 RS20810
gene id: 927083:DB32_RS20810
uniprot id: A0A0F6YJJ9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS07755
gene id: 927083:DB32_RS07755
uniprot id: A0A0F6YH13
names: Similarity
messages: Belongs to the AHA1 family.

927083:DB32 RS23290
gene id: 927083:DB32_RS23290
uniprot id: A0A0F6SFV5
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

927083:DB32 RS30845
gene id: 927083:DB32_RS30845
uniprot id: A0A0F6W756
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

927083:DB32 RS15090
gene id: 927083:DB32_RS15090
uniprot id: A0A0F6SEX3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

927083:DB32 RS14625
gene id: 927083:DB32_RS14625
uniprot id: A0A0F6YHM1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

927083:DB32 RS25235
gene id: 927083:DB32_RS25235
uniprot id: A0A0F6W5T5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

927083:DB32 RS26460
gene id: 927083:DB32_RS26460
uniprot id: A0A0F6YJX1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

927083:DB32 RS15995
gene id: 927083:DB32_RS15995
uniprot id: A0A0F6YJI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

927083:DB32 RS30815
gene id: 927083:DB32_RS30815
uniprot id: A0A0F6SGR4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

927083:DB32 RS30780
gene id: 927083:DB32_RS30780
uniprot id: A0A0F6YKH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

927083:DB32 RS24450
gene id: 927083:DB32_RS24450
uniprot id: A0A0F6W5A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

927083:DB32 RS35440
gene id: 927083:DB32_RS35440
uniprot id: A0A0F6SHA2
names: Similarity
messages: Belongs to the pirin family.

927083:DB32 RS36350
gene id: 927083:DB32_RS36350
uniprot id: A0A0F6YLD7
names: Similarity
messages: Belongs to the GST superfamily.

927083:DB32 RS24145
gene id: 927083:DB32_RS24145
uniprot id: A0A0F6W572
names: Subcellular Location Annotation
messages: Cytoplasm

927083:DB32 RS21145
gene id: 927083:DB32_RS21145
uniprot id: A0A0F6YJC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

927083:DB32 RS38080
gene id: 927083:DB32_RS38080
uniprot id: A0A0F6YM38
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

927083:DB32 RS03890
gene id: 927083:DB32_RS03890
uniprot id: A0A0F6VZJ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS14740
gene id: 927083:DB32_RS14740
uniprot id: A0A0F6W2K1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

927083:DB32 RS05155
gene id: 927083:DB32_RS05155
uniprot id: A0A0F6YFN2
names: Similarity
messages: Belongs to the FPG family.

927083:DB32 RS05310
gene id: 927083:DB32_RS05310
uniprot id: A0A0F6YFP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

927083:DB32 RS38185
gene id: 927083:DB32_RS38185
uniprot id: A0A0F6W951
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

927083:DB32 RS38095
gene id: 927083:DB32_RS38095
uniprot id: A0A0F6SHK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

927083:DB32 RS26235
gene id: 927083:DB32_RS26235
uniprot id: A0A0F6W5V6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

927083:DB32 RS42490
gene id: 927083:DB32_RS42490
uniprot id: A0A0F6YMW3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS13185
gene id: 927083:DB32_RS13185
uniprot id: A0A0F6SHL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

927083:DB32 RS18635
gene id: 927083:DB32_RS18635
uniprot id: A0A0F6SFB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

927083:DB32 RS37145
gene id: 927083:DB32_RS37145
uniprot id: A0A0F6YNG9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

927083:DB32 RS25490
gene id: 927083:DB32_RS25490
uniprot id: A0A0F6W5V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

927083:DB32 RS05085
gene id: 927083:DB32_RS05085
uniprot id: A0A0F6YFM9
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS18650
gene id: 927083:DB32_RS18650
uniprot id: A0A0F6W3N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

927083:DB32 RS30225
gene id: 927083:DB32_RS30225
uniprot id: A0A0F6W6W6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

927083:DB32 RS23115
gene id: 927083:DB32_RS23115
uniprot id: A0A0F6YKT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Membrane

927083:DB32 RS08175
gene id: 927083:DB32_RS08175
uniprot id: A0A0F6YHZ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS06205
gene id: 927083:DB32_RS06205
uniprot id: A0A0F6SDV7
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS34570
gene id: 927083:DB32_RS34570
uniprot id: A0A0F6YN27
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS15510
gene id: 927083:DB32_RS15510
uniprot id: A0A0F6YIF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

927083:DB32 RS25880
gene id: 927083:DB32_RS25880
uniprot id: A0A0F6W5N7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

927083:DB32 RS13155
gene id: 927083:DB32_RS13155
uniprot id: A0A0F6SEP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

927083:DB32 RS39320
gene id: 927083:DB32_RS39320
uniprot id: A0A0F6W9H1
names: Similarity
messages: Belongs to the DEAD box helicase family.

927083:DB32 RS24835
gene id: 927083:DB32_RS24835
uniprot id: A0A0F6W5I2
names: Similarity
messages: Belongs to the PspA/IM30 family.

927083:DB32 RS09360
gene id: 927083:DB32_RS09360
uniprot id: A0A0F6W144
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

927083:DB32 RS21535
gene id: 927083:DB32_RS21535
uniprot id: A0A0F6YIQ2
names: Subunit
messages: Heterodimer of a large and a small subunit.

927083:DB32 RS29285
gene id: 927083:DB32_RS29285
uniprot id: A0A0F6SGK2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

927083:DB32 RS13300
gene id: 927083:DB32_RS13300
uniprot id: A0A0F6SEP9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

927083:DB32 RS14300
gene id: 927083:DB32_RS14300
uniprot id: A0A0F6SEU1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

927083:DB32 RS39200
gene id: 927083:DB32_RS39200
uniprot id: A0A0F6W9I7
names: Similarity
messages: Belongs to the YciI family.

927083:DB32 RS12215
gene id: 927083:DB32_RS12215
uniprot id: A0A0F6W1V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

927083:DB32 RS38175
gene id: 927083:DB32_RS38175
uniprot id: A0A0F6YMS2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

927083:DB32 RS22860
gene id: 927083:DB32_RS22860
uniprot id: A0A0F6YJN7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

927083:DB32 RS11825
gene id: 927083:DB32_RS11825
uniprot id: A0A0F6W1R2
names: Similarity
messages: Belongs to the Lgt family.

927083:DB32 RS11185
gene id: 927083:DB32_RS11185
uniprot id: A0A0F6W1J5
names: Similarity
messages: Belongs to the peptidase S49 family.

927083:DB32 RS22540
gene id: 927083:DB32_RS22540
uniprot id: A0A0F6YJL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

927083:DB32 RS40825
gene id: 927083:DB32_RS40825
uniprot id: A0A0F6WA21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

927083:DB32 RS44840
gene id: 927083:DB32_RS44840
uniprot id: A0A0F6YPK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

927083:DB32 RS33270
gene id: 927083:DB32_RS33270
uniprot id: A0A0F6SH15
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

927083:DB32 RS04975
gene id: 927083:DB32_RS04975
uniprot id: A0A0F6SDQ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

927083:DB32 RS25190
gene id: 927083:DB32_RS25190
uniprot id: A0A0F6SG34
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS42090
gene id: 927083:DB32_RS42090
uniprot id: A0A0F6WAE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

927083:DB32 RS12225
gene id: 927083:DB32_RS12225
uniprot id: A0A0F6W248
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS00385
gene id: 927083:DB32_RS00385
uniprot id: A0A0F6YEW8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

927083:DB32 RS20715
gene id: 927083:DB32_RS20715
uniprot id: A0A0F6SFK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

927083:DB32 RS25725
gene id: 927083:DB32_RS25725
uniprot id: A0A0F6W5M7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

927083:DB32 RS28565
gene id: 927083:DB32_RS28565
uniprot id: A0A0F6SGH3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS03925
gene id: 927083:DB32_RS03925
uniprot id: A0A0F6YG97
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

927083:DB32 RS18000
gene id: 927083:DB32_RS18000
uniprot id: A0A0F6W3G9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

927083:DB32 RS31970
gene id: 927083:DB32_RS31970
uniprot id: A0A0F6SGW2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

927083:DB32 RS41575
gene id: 927083:DB32_RS41575
uniprot id: A0A0F6WA65
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

927083:DB32 RS16280
gene id: 927083:DB32_RS16280
uniprot id: A0A0F6YIJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

927083:DB32 RS08680
gene id: 927083:DB32_RS08680
uniprot id: A0A0F6W154
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

927083:DB32 RS10530
gene id: 927083:DB32_RS10530
uniprot id: A0A0F6W1G3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

927083:DB32 RS28185
gene id: 927083:DB32_RS28185
uniprot id: A0A0F6YLT2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

927083:DB32 RS04835
gene id: 927083:DB32_RS04835
uniprot id: A0A0F6SDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

927083:DB32 RS11345
gene id: 927083:DB32_RS11345
uniprot id: A0A0F6W1L0
names: Similarity
messages: Belongs to the histone deacetylase family.

927083:DB32 RS09930
gene id: 927083:DB32_RS09930
uniprot id: A0A0F6W1B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

927083:DB32 RS24865
gene id: 927083:DB32_RS24865
uniprot id: A0A0F6SG20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

927083:DB32 RS24425
gene id: 927083:DB32_RS24425
uniprot id: A0A0F6YK95
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

927083:DB32 RS27660
gene id: 927083:DB32_RS27660
uniprot id: A0A0F6W666
names: Similarity
messages: Belongs to the universal stress protein A family.

927083:DB32 RS13555
gene id: 927083:DB32_RS13555
uniprot id: A0A0F6W2B3
names: Similarity
messages: Belongs to the UPF0751 family.

927083:DB32 RS24430
gene id: 927083:DB32_RS24430
uniprot id: A0A0F6SG02
names: Similarity
messages: Belongs to the cytochrome P450 family.

927083:DB32 RS27460
gene id: 927083:DB32_RS27460
uniprot id: A0A0F6SGC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

927083:DB32 RS46580
gene id: 927083:DB32_RS46580
uniprot id: A0A0F6YIC6
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

927083:DB32 RS43185
gene id: 927083:DB32_RS43185
uniprot id: A0A0F6YN01
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS44350
gene id: 927083:DB32_RS44350
uniprot id: A0A0F6W464
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

927083:DB32 RS41485
gene id: 927083:DB32_RS41485
uniprot id: A0A0F6WA41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

927083:DB32 RS22890
gene id: 927083:DB32_RS22890
uniprot id: A0A0F6YKP5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

927083:DB32 RS19615
gene id: 927083:DB32_RS19615
uniprot id: A0A0F6YIC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

927083:DB32 RS03100
gene id: 927083:DB32_RS03100
uniprot id: A0A0F6VZI3
names: PTM
names: Similarity
messages: Belongs to the photoactive yellow protein family.
messages: The 4-hydroxycinnamic acid (p-coumaric acid) chromophore is covalently bound via a thioester linkage.

927083:DB32 RS28350
gene id: 927083:DB32_RS28350
uniprot id: A0A0F6W6H6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

927083:DB32 RS01875
gene id: 927083:DB32_RS01875
uniprot id: A0A0F6SDD2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

927083:DB32 RS47925
gene id: 927083:DB32_RS47925
uniprot id: A0A0F6YFI4
names: Similarity
messages: Belongs to the peptidase A24 family.

927083:DB32 RS02260
gene id: 927083:DB32_RS02260
uniprot id: A0A0F6VZ48
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS29075
gene id: 927083:DB32_RS29075
uniprot id: A0A0F6W6N9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

927083:DB32 RS24455
gene id: 927083:DB32_RS24455
uniprot id: A0A0F6SG03
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

927083:DB32 RS06110
gene id: 927083:DB32_RS06110
uniprot id: A0A0F6SDV3
names: Similarity
messages: Belongs to the ArsC family.

927083:DB32 RS22180
gene id: 927083:DB32_RS22180
uniprot id: A0A0F6W4N6
names: Similarity
messages: Belongs to the FPG family.

927083:DB32 RS31270
gene id: 927083:DB32_RS31270
uniprot id: A0A0F6W7I0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

927083:DB32 RS18580
gene id: 927083:DB32_RS18580
uniprot id: A0A0F6W3Q7
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

927083:DB32 RS13425
gene id: 927083:DB32_RS13425
uniprot id: A0A0F6SEQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

927083:DB32 RS24985
gene id: 927083:DB32_RS24985
uniprot id: A0A0F6W5G8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

927083:DB32 RS31640
gene id: 927083:DB32_RS31640
uniprot id: A0A0F6W7E3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

927083:DB32 RS09920
gene id: 927083:DB32_RS09920
uniprot id: A0A0F6SEB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

927083:DB32 RS21675
gene id: 927083:DB32_RS21675
uniprot id: A0A0F6YJF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

927083:DB32 RS19640
gene id: 927083:DB32_RS19640
uniprot id: A0A0F6W478
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

927083:DB32 RS15165
gene id: 927083:DB32_RS15165
uniprot id: A0A0F6SEX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

927083:DB32 RS35645
gene id: 927083:DB32_RS35645
uniprot id: A0A0F6W8N0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS36825
gene id: 927083:DB32_RS36825
uniprot id: A0A0F6W8R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

927083:DB32 RS28965
gene id: 927083:DB32_RS28965
uniprot id: A0A0F6W6I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

927083:DB32 RS24760
gene id: 927083:DB32_RS24760
uniprot id: A0A0F6W5D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

927083:DB32 RS25300
gene id: 927083:DB32_RS25300
uniprot id: A0A0F6W5U0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

927083:DB32 RS05840
gene id: 927083:DB32_RS05840
uniprot id: A0A0F6SDU2
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS07425
gene id: 927083:DB32_RS07425
uniprot id: A0A0F6YH30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

927083:DB32 RS32625
gene id: 927083:DB32_RS32625
uniprot id: A0A0F6YLJ4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

927083:DB32 RS32665
gene id: 927083:DB32_RS32665
uniprot id: A0A0F6YMQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

927083:DB32 RS17025
gene id: 927083:DB32_RS17025
uniprot id: A0A0F6SF50
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

927083:DB32 RS05365
gene id: 927083:DB32_RS05365
uniprot id: A0A0F6W084
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

927083:DB32 RS24115
gene id: 927083:DB32_RS24115
uniprot id: A0A0F6W569
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

927083:DB32 RS11915
gene id: 927083:DB32_RS11915
uniprot id: A0A0F6SEJ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS15180
gene id: 927083:DB32_RS15180
uniprot id: A0A0F6W2P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

927083:DB32 RS09005
gene id: 927083:DB32_RS09005
uniprot id: A0A0F6W180
names: Similarity
messages: Belongs to the asparagine synthetase family.

927083:DB32 RS21465
gene id: 927083:DB32_RS21465
uniprot id: A0A0F6W4J2
names: Similarity
messages: Belongs to the BtpA family.

927083:DB32 RS13375
gene id: 927083:DB32_RS13375
uniprot id: A0A0F6W273
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS25945
gene id: 927083:DB32_RS25945
uniprot id: A0A0F6YKH7
names: Similarity
messages: Belongs to the CinA family.

927083:DB32 RS22335
gene id: 927083:DB32_RS22335
uniprot id: A0A0F6W4S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

927083:DB32 RS17580
gene id: 927083:DB32_RS17580
uniprot id: A0A0F6W3L8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

927083:DB32 RS13690
gene id: 927083:DB32_RS13690
uniprot id: A0A0F6SER6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

927083:DB32 RS25800
gene id: 927083:DB32_RS25800
uniprot id: A0A0F6YKG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

927083:DB32 RS38320
gene id: 927083:DB32_RS38320
uniprot id: A0A0F6W999
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS28225
gene id: 927083:DB32_RS28225
uniprot id: A0A0F6W6N2
names: Similarity
messages: Belongs to the fructosamine kinase family.

927083:DB32 RS36605
gene id: 927083:DB32_RS36605
uniprot id: A0A0F6W8V6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS34640
gene id: 927083:DB32_RS34640
uniprot id: A0A0F6W8E3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

927083:DB32 RS10465
gene id: 927083:DB32_RS10465
uniprot id: A0A0F6W1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

927083:DB32 RS37990
gene id: 927083:DB32_RS37990
uniprot id: A0A0F6W969
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

927083:DB32 RS14950
gene id: 927083:DB32_RS14950
uniprot id: A0A0F6YIH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

927083:DB32 RS47405
gene id: 927083:DB32_RS47405
uniprot id: A0A0F6YLA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

927083:DB32 RS28365
gene id: 927083:DB32_RS28365
uniprot id: A0A0F6YKW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

927083:DB32 RS18575
gene id: 927083:DB32_RS18575
uniprot id: A0A0F6YIG2
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

927083:DB32 RS31330
gene id: 927083:DB32_RS31330
uniprot id: A0A0F6YKZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

927083:DB32 RS21770
gene id: 927083:DB32_RS21770
uniprot id: A0A0F6YIR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

927083:DB32 RS37280
gene id: 927083:DB32_RS37280
uniprot id: A0A0F6W8X9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

927083:DB32 RS27415
gene id: 927083:DB32_RS27415
uniprot id: A0A0F6W679
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS06490
gene id: 927083:DB32_RS06490
uniprot id: A0A0F6W0A5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

927083:DB32 RS14120
gene id: 927083:DB32_RS14120
uniprot id: A0A0F6YI39
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

927083:DB32 RS28705
gene id: 927083:DB32_RS28705
uniprot id: A0A0F6YLW0
names: Similarity
messages: Belongs to the isochorismate synthase family.

927083:DB32 RS13015
gene id: 927083:DB32_RS13015
uniprot id: A0A0F6W2E7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

927083:DB32 RS26435
gene id: 927083:DB32_RS26435
uniprot id: A0A0F6W646
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS38695
gene id: 927083:DB32_RS38695
uniprot id: A0A0F6W9D4
names: Similarity
messages: Belongs to the universal stress protein A family.

927083:DB32 RS21775
gene id: 927083:DB32_RS21775
uniprot id: A0A0F6W4N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

927083:DB32 RS21750
gene id: 927083:DB32_RS21750
uniprot id: A0A0F6W4K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

927083:DB32 RS11680
gene id: 927083:DB32_RS11680
uniprot id: A0A0F6SEI3
names: Similarity
messages: Belongs to the peptidase C56 family.

927083:DB32 RS18640
gene id: 927083:DB32_RS18640
uniprot id: A0A0F6YJX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

927083:DB32 RS30210
gene id: 927083:DB32_RS30210
uniprot id: A0A0F6YL16
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

927083:DB32 RS25230
gene id: 927083:DB32_RS25230
uniprot id: A0A0F6YJN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

927083:DB32 RS05120
gene id: 927083:DB32_RS05120
uniprot id: A0A0F6SDR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

927083:DB32 RS23330
gene id: 927083:DB32_RS23330
uniprot id: A0A0F6YKU0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

927083:DB32 RS04380
gene id: 927083:DB32_RS04380
uniprot id: A0A0F6SDN1
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

927083:DB32 RS42425
gene id: 927083:DB32_RS42425
uniprot id: A0A0F6WAH6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS38110
gene id: 927083:DB32_RS38110
uniprot id: A0A0F6YMC9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

927083:DB32 RS16055
gene id: 927083:DB32_RS16055
uniprot id: A0A0F6W384
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

927083:DB32 RS18330
gene id: 927083:DB32_RS18330
uniprot id: A0A0F6W3P0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

927083:DB32 RS41400
gene id: 927083:DB32_RS41400
uniprot id: A0A0F6YPB0
names: Subcellular Location Annotation
messages: Cytoplasm

927083:DB32 RS38205
gene id: 927083:DB32_RS38205
uniprot id: A0A0F6YLR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

927083:DB32 RS25270
gene id: 927083:DB32_RS25270
uniprot id: A0A0F6W5T7
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

927083:DB32 RS24410
gene id: 927083:DB32_RS24410
uniprot id: A0A0F6W5H8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

927083:DB32 RS10730
gene id: 927083:DB32_RS10730
uniprot id: A0A0F6W1I4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS03865
gene id: 927083:DB32_RS03865
uniprot id: A0A0F6YFJ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS12940
gene id: 927083:DB32_RS12940
uniprot id: A0A0F6SEN5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS16165
gene id: 927083:DB32_RS16165
uniprot id: A0A0F6W301
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

927083:DB32 RS02330
gene id: 927083:DB32_RS02330
uniprot id: A0A0F6YGW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

927083:DB32 RS09985
gene id: 927083:DB32_RS09985
uniprot id: A0A0F6W1C1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

927083:DB32 RS26485
gene id: 927083:DB32_RS26485
uniprot id: A0A0F6W5U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

927083:DB32 RS20920
gene id: 927083:DB32_RS20920
uniprot id: A0A0F6W4E0
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

927083:DB32 RS25500
gene id: 927083:DB32_RS25500
uniprot id: A0A0F6YK85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

927083:DB32 RS07165
gene id: 927083:DB32_RS07165
uniprot id: A0A0F6W0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

927083:DB32 RS23545
gene id: 927083:DB32_RS23545
uniprot id: A0A0F6W5A7
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

927083:DB32 RS06275
gene id: 927083:DB32_RS06275
uniprot id: A0A0F6SDW0
names: Similarity
messages: Belongs to the cytochrome P450 family.

927083:DB32 RS32440
gene id: 927083:DB32_RS32440
uniprot id: A0A0F6W7I1
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS07990
gene id: 927083:DB32_RS07990
uniprot id: A0A0F6W0Z7
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS16645
gene id: 927083:DB32_RS16645
uniprot id: A0A0F6W368
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS28685
gene id: 927083:DB32_RS28685
uniprot id: A0A0F6W6G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

927083:DB32 RS37000
gene id: 927083:DB32_RS37000
uniprot id: A0A0F6W8W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

927083:DB32 RS06145
gene id: 927083:DB32_RS06145
uniprot id: A0A0F6YFW1
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS31610
gene id: 927083:DB32_RS31610
uniprot id: A0A0F6W7E0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

927083:DB32 RS41030
gene id: 927083:DB32_RS41030
uniprot id: A0A0F6W9Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

927083:DB32 RS44050
gene id: 927083:DB32_RS44050
uniprot id: A0A0F6W062
names: Similarity
messages: Belongs to the GSP E family.

927083:DB32 RS03710
gene id: 927083:DB32_RS03710
uniprot id: A0A0F6YG86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

927083:DB32 RS32930
gene id: 927083:DB32_RS32930
uniprot id: A0A0F6W7S0
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

927083:DB32 RS38200
gene id: 927083:DB32_RS38200
uniprot id: A0A0F6W9B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

927083:DB32 RS32140
gene id: 927083:DB32_RS32140
uniprot id: A0A0F6W7J0
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

927083:DB32 RS08060
gene id: 927083:DB32_RS08060
uniprot id: A0A0F6YH33
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS40745
gene id: 927083:DB32_RS40745
uniprot id: A0A0F6SHW7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

927083:DB32 RS23345
gene id: 927083:DB32_RS23345
uniprot id: A0A0F6YJB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

927083:DB32 RS48260
gene id: 927083:DB32_RS48260
uniprot id: A0A0F6W329
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

927083:DB32 RS17235
gene id: 927083:DB32_RS17235
uniprot id: A0A0F6SF59
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS23230
gene id: 927083:DB32_RS23230
uniprot id: A0A0F6YJW6
names: Similarity
messages: Belongs to the DEAD box helicase family.

927083:DB32 RS20640
gene id: 927083:DB32_RS20640
uniprot id: A0A0F6W476
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

927083:DB32 RS03050
gene id: 927083:DB32_RS03050
uniprot id: A0A0F6VZB3
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

927083:DB32 RS10555
gene id: 927083:DB32_RS10555
uniprot id: A0A0F6W1D9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

927083:DB32 RS24165
gene id: 927083:DB32_RS24165
uniprot id: A0A0F6YKY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

927083:DB32 RS43130
gene id: 927083:DB32_RS43130
uniprot id: A0A0F6WAN1
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS05245
gene id: 927083:DB32_RS05245
uniprot id: A0A0F6W072
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

927083:DB32 RS33295
gene id: 927083:DB32_RS33295
uniprot id: A0A0F6SH16
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

927083:DB32 RS00795
gene id: 927083:DB32_RS00795
uniprot id: A0A0F6YFS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

927083:DB32 RS38840
gene id: 927083:DB32_RS38840
uniprot id: A0A0F6SHN8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

927083:DB32 RS12745
gene id: 927083:DB32_RS12745
uniprot id: A0A0F6W2C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

927083:DB32 RS42510
gene id: 927083:DB32_RS42510
uniprot id: A0A0F6YNI8
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

927083:DB32 RS17525
gene id: 927083:DB32_RS17525
uniprot id: A0A0F6SF71
names: Similarity
messages: Belongs to the aspartokinase family.

927083:DB32 RS09295
gene id: 927083:DB32_RS09295
uniprot id: A0A0F6SE85
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

927083:DB32 RS03445
gene id: 927083:DB32_RS03445
uniprot id: A0A0F6YFD8
names: Similarity
messages: Belongs to the AHA1 family.

927083:DB32 RS22775
gene id: 927083:DB32_RS22775
uniprot id: A0A0F6W533
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

927083:DB32 RS04775
gene id: 927083:DB32_RS04775
uniprot id: A0A0F6YHB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

927083:DB32 RS06855
gene id: 927083:DB32_RS06855
uniprot id: A0A0F6W0D2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

927083:DB32 RS35125
gene id: 927083:DB32_RS35125
uniprot id: A0A0F6W8I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

927083:DB32 RS08630
gene id: 927083:DB32_RS08630
uniprot id: A0A0F6YGF4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS30250
gene id: 927083:DB32_RS30250
uniprot id: A0A0F6W704
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

927083:DB32 RS13755
gene id: 927083:DB32_RS13755
uniprot id: A0A0F6W2D3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

927083:DB32 RS14150
gene id: 927083:DB32_RS14150
uniprot id: A0A0F6YJ26
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

927083:DB32 RS11235
gene id: 927083:DB32_RS11235
uniprot id: A0A0F6YHH4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

927083:DB32 RS06630
gene id: 927083:DB32_RS06630
uniprot id: A0A0F6YHL2
names: Subunit
messages: Heterodimer of a large and a small subunit.

927083:DB32 RS10935
gene id: 927083:DB32_RS10935
uniprot id: A0A0F6SEF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

927083:DB32 RS13305
gene id: 927083:DB32_RS13305
uniprot id: A0A0F6W265
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

927083:DB32 RS01505
gene id: 927083:DB32_RS01505
uniprot id: A0A0F6VYW1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS07155
gene id: 927083:DB32_RS07155
uniprot id: A0A0F6YHP0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

927083:DB32 RS20900
gene id: 927083:DB32_RS20900
uniprot id: A0A0F6SFK8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

927083:DB32 RS15200
gene id: 927083:DB32_RS15200
uniprot id: A0A0F6YIA8
names: Similarity
messages: Belongs to the TPP enzyme family.

927083:DB32 RS20075
gene id: 927083:DB32_RS20075
uniprot id: A0A0F6W4B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

927083:DB32 RS48295
gene id: 927083:DB32_RS48295
uniprot id: A0A0F6W3N1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

927083:DB32 RS16920
gene id: 927083:DB32_RS16920
uniprot id: A0A0F6W3F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

927083:DB32 RS38125
gene id: 927083:DB32_RS38125
uniprot id: A0A0F6W945
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

927083:DB32 RS19880
gene id: 927083:DB32_RS19880
uniprot id: A0A0F6SFG7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

927083:DB32 RS41790
gene id: 927083:DB32_RS41790
uniprot id: A0A0F6SI10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

927083:DB32 RS25830
gene id: 927083:DB32_RS25830
uniprot id: A0A0F6YJJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

927083:DB32 RS04875
gene id: 927083:DB32_RS04875
uniprot id: A0A0F6YGM0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

927083:DB32 RS22880
gene id: 927083:DB32_RS22880
uniprot id: A0A0F6W4X3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS15680
gene id: 927083:DB32_RS15680
uniprot id: A0A0F6YHR1
names: Similarity
messages: Belongs to the MT-A70-like family.

927083:DB32 RS24215
gene id: 927083:DB32_RS24215
uniprot id: A0A0F6W5A9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

927083:DB32 RS18600
gene id: 927083:DB32_RS18600
uniprot id: A0A0F6W3V7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS27990
gene id: 927083:DB32_RS27990
uniprot id: A0A0F6W6E5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

927083:DB32 RS38195
gene id: 927083:DB32_RS38195
uniprot id: A0A0F6SHL2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

927083:DB32 RS18740
gene id: 927083:DB32_RS18740
uniprot id: A0A0F6W3T8
names: Similarity
messages: Belongs to the GSP E family.

927083:DB32 RS27740
gene id: 927083:DB32_RS27740
uniprot id: A0A0F6YK64
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

927083:DB32 RS25520
gene id: 927083:DB32_RS25520
uniprot id: A0A0F6SG47
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS26765
gene id: 927083:DB32_RS26765
uniprot id: A0A0F6W677
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

927083:DB32 RS40370
gene id: 927083:DB32_RS40370
uniprot id: A0A0F6W9T5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS28085
gene id: 927083:DB32_RS28085
uniprot id: A0A0F6W6C0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

927083:DB32 RS28360
gene id: 927083:DB32_RS28360
uniprot id: A0A0F6W6D9
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS03090
gene id: 927083:DB32_RS03090
uniprot id: A0A0F6YGB0
names: Similarity
messages: Belongs to the group II decarboxylase family.

927083:DB32 RS26335
gene id: 927083:DB32_RS26335
uniprot id: A0A0F6YKD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Membrane

927083:DB32 RS30245
gene id: 927083:DB32_RS30245
uniprot id: A0A0F6YM51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.
messages: Might have a role in establishing the nucleoid structure of elementary bodies.

927083:DB32 RS16710
gene id: 927083:DB32_RS16710
uniprot id: A0A0F6W341
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS28670
gene id: 927083:DB32_RS28670
uniprot id: A0A0F6W6S6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

927083:DB32 RS23175
gene id: 927083:DB32_RS23175
uniprot id: A0A0F6SFV0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

927083:DB32 RS12840
gene id: 927083:DB32_RS12840
uniprot id: A0A0F6SEN1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

927083:DB32 RS02510
gene id: 927083:DB32_RS02510
uniprot id: A0A0F6VZ72
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

927083:DB32 RS33250
gene id: 927083:DB32_RS33250
uniprot id: A0A0F6W7R5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

927083:DB32 RS15135
gene id: 927083:DB32_RS15135
uniprot id: A0A0F6YHJ1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

927083:DB32 RS24400
gene id: 927083:DB32_RS24400
uniprot id: A0A0F6W597
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

927083:DB32 RS03880
gene id: 927083:DB32_RS03880
uniprot id: A0A0F6SDL0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

927083:DB32 RS48195
gene id: 927083:DB32_RS48195
uniprot id: A0A0F6YJ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

927083:DB32 RS40655
gene id: 927083:DB32_RS40655
uniprot id: A0A0F6WA03
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

927083:DB32 RS29795
gene id: 927083:DB32_RS29795
uniprot id: A0A0F6W731
names: Similarity
messages: Belongs to the ClpA/ClpB family.

927083:DB32 RS17050
gene id: 927083:DB32_RS17050
uniprot id: A0A0F6SF51
names: Similarity
messages: Belongs to the fatty acyl-CoA reductase family.

927083:DB32 RS35045
gene id: 927083:DB32_RS35045
uniprot id: A0A0F6YL67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

927083:DB32 RS27585
gene id: 927083:DB32_RS27585
uniprot id: A0A0F6YK54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

927083:DB32 RS35175
gene id: 927083:DB32_RS35175
uniprot id: A0A0F6SH91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS22070
gene id: 927083:DB32_RS22070
uniprot id: A0A0F6SFQ6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

927083:DB32 RS03570
gene id: 927083:DB32_RS03570
uniprot id: A0A0F6VZG5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

927083:DB32 RS04145
gene id: 927083:DB32_RS04145
uniprot id: A0A0F6VZW5
names: Similarity
messages: Belongs to the TrpF family.

927083:DB32 RS18445
gene id: 927083:DB32_RS18445
uniprot id: A0A0F6W3U0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS18830
gene id: 927083:DB32_RS18830
uniprot id: A0A0F6SFC4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

927083:DB32 RS40785
gene id: 927083:DB32_RS40785
uniprot id: A0A0F6W9Z0
names: Similarity
messages: Belongs to the pyruvate kinase family.

927083:DB32 RS23095
gene id: 927083:DB32_RS23095
uniprot id: A0A0F6W4W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

927083:DB32 RS42130
gene id: 927083:DB32_RS42130
uniprot id: A0A0F6WAB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS03795
gene id: 927083:DB32_RS03795
uniprot id: A0A0F6YFI6
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS41260
gene id: 927083:DB32_RS41260
uniprot id: A0A0F6YMP7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

927083:DB32 RS38130
gene id: 927083:DB32_RS38130
uniprot id: A0A0F6YLQ6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

927083:DB32 RS42000
gene id: 927083:DB32_RS42000
uniprot id: A0A0F6YMJ4
names: Similarity
messages: Belongs to the UPF0167 family.

927083:DB32 RS30600
gene id: 927083:DB32_RS30600
uniprot id: A0A0F6YLA9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

927083:DB32 RS13655
gene id: 927083:DB32_RS13655
uniprot id: A0A0F6W2K7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

927083:DB32 RS20450
gene id: 927083:DB32_RS20450
uniprot id: A0A0F6W4F2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

927083:DB32 RS32330
gene id: 927083:DB32_RS32330
uniprot id: A0A0F6SGX7
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

927083:DB32 RS15150
gene id: 927083:DB32_RS15150
uniprot id: A0A0F6W2P3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

927083:DB32 RS10120
gene id: 927083:DB32_RS10120
uniprot id: A0A0F6W1A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

927083:DB32 RS19530
gene id: 927083:DB32_RS19530
uniprot id: A0A0F6W407
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

927083:DB32 RS03220
gene id: 927083:DB32_RS03220
uniprot id: A0A0F6YFC4
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS26615
gene id: 927083:DB32_RS26615
uniprot id: A0A0F6YKL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

927083:DB32 RS09580
gene id: 927083:DB32_RS09580
uniprot id: A0A0F6SE97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS34320
gene id: 927083:DB32_RS34320
uniprot id: A0A0F6YN12
names: Similarity
messages: Belongs to the peptidase S33 family.

927083:DB32 RS29275
gene id: 927083:DB32_RS29275
uniprot id: A0A0F6YL25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

927083:DB32 RS41500
gene id: 927083:DB32_RS41500
uniprot id: A0A0F6WA87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

927083:DB32 RS42330
gene id: 927083:DB32_RS42330
uniprot id: A0A0F6YPH6
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

927083:DB32 RS35435
gene id: 927083:DB32_RS35435
uniprot id: A0A0F6YMB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

927083:DB32 RS22925
gene id: 927083:DB32_RS22925
uniprot id: A0A0F6W548
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

927083:DB32 RS26170
gene id: 927083:DB32_RS26170
uniprot id: A0A0F6W5V0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

927083:DB32 RS09805
gene id: 927083:DB32_RS09805
uniprot id: A0A0F6W1A4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

927083:DB32 RS18090
gene id: 927083:DB32_RS18090
uniprot id: A0A0F6W3L9
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS08545
gene id: 927083:DB32_RS08545
uniprot id: A0A0F6SE54
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

927083:DB32 RS02515
gene id: 927083:DB32_RS02515
uniprot id: A0A0F6VZ64
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

927083:DB32 RS13170
gene id: 927083:DB32_RS13170
uniprot id: A0A0F6W2G2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS06565
gene id: 927083:DB32_RS06565
uniprot id: A0A0F6W0B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

927083:DB32 RS02455
gene id: 927083:DB32_RS02455
uniprot id: A0A0F6VZ58
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

927083:DB32 RS44565
gene id: 927083:DB32_RS44565
uniprot id: A0A0F6YMD8
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

927083:DB32 RS38300
gene id: 927083:DB32_RS38300
uniprot id: A0A0F6YLR6
names: Caution
names: Function
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possible subunit of a heme lyase.

927083:DB32 RS10420
gene id: 927083:DB32_RS10420
uniprot id: A0A0F6W1F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

927083:DB32 RS15450
gene id: 927083:DB32_RS15450
uniprot id: A0A0F6YHP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

927083:DB32 RS17340
gene id: 927083:DB32_RS17340
uniprot id: A0A0F6YJR1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

927083:DB32 RS13150
gene id: 927083:DB32_RS13150
uniprot id: A0A0F6W281
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

927083:DB32 RS20905
gene id: 927083:DB32_RS20905
uniprot id: A0A0F6YJK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

927083:DB32 RS32420
gene id: 927083:DB32_RS32420
uniprot id: A0A0F6W7T5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

927083:DB32 RS04390
gene id: 927083:DB32_RS04390
uniprot id: A0A0F6VZP5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

927083:DB32 RS16235
gene id: 927083:DB32_RS16235
uniprot id: A0A0F6W3A1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

927083:DB32 RS16845
gene id: 927083:DB32_RS16845
uniprot id: A0A0F6W3F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

927083:DB32 RS25955
gene id: 927083:DB32_RS25955
uniprot id: A0A0F6YKB6
names: Similarity
messages: Belongs to the peptidase M16 family.

927083:DB32 RS18010
gene id: 927083:DB32_RS18010
uniprot id: A0A0F6W3Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

927083:DB32 RS12365
gene id: 927083:DB32_RS12365
uniprot id: A0A0F6YHS1
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS23980
gene id: 927083:DB32_RS23980
uniprot id: A0A0F6YK00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

927083:DB32 RS33180
gene id: 927083:DB32_RS33180
uniprot id: A0A0F6W7U5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS12475
gene id: 927083:DB32_RS12475
uniprot id: A0A0F6YIR6
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS16220
gene id: 927083:DB32_RS16220
uniprot id: A0A0F6SF19
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

927083:DB32 RS11045
gene id: 927083:DB32_RS11045
uniprot id: A0A0F6W1U6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS12035
gene id: 927083:DB32_RS12035
uniprot id: A0A0F6W1W5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

927083:DB32 RS20015
gene id: 927083:DB32_RS20015
uniprot id: A0A0F6SFH2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS11135
gene id: 927083:DB32_RS11135
uniprot id: A0A0F6W1V5
names: Similarity
messages: Belongs to the CapA family.

927083:DB32 RS34870
gene id: 927083:DB32_RS34870
uniprot id: A0A0F6W878
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS42260
gene id: 927083:DB32_RS42260
uniprot id: A0A0F6WAC8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

927083:DB32 RS43375
gene id: 927083:DB32_RS43375
uniprot id: A0A0F6SI75
names: Similarity
messages: Belongs to the glutathione peroxidase family.

927083:DB32 RS18380
gene id: 927083:DB32_RS18380
uniprot id: A0A0F6W3T3
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS21790
gene id: 927083:DB32_RS21790
uniprot id: A0A0F6YKH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS15365
gene id: 927083:DB32_RS15365
uniprot id: A0A0F6W2U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

927083:DB32 RS05540
gene id: 927083:DB32_RS05540
uniprot id: A0A0F6YFQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

927083:DB32 RS23370
gene id: 927083:DB32_RS23370
uniprot id: A0A0F6YJX6
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS14580
gene id: 927083:DB32_RS14580
uniprot id: A0A0F6W2L4
names: Similarity
messages: Belongs to the BolA/IbaG family.

927083:DB32 RS13050
gene id: 927083:DB32_RS13050
uniprot id: A0A0F6SEP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

927083:DB32 RS10210
gene id: 927083:DB32_RS10210
uniprot id: A0A0F6W1A8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

927083:DB32 RS03020
gene id: 927083:DB32_RS03020
uniprot id: A0A0F6VZB0
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

927083:DB32 RS42005
gene id: 927083:DB32_RS42005
uniprot id: A0A0F6WAA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

927083:DB32 RS20755
gene id: 927083:DB32_RS20755
uniprot id: A0A0F6W4C5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

927083:DB32 RS42715
gene id: 927083:DB32_RS42715
uniprot id: A0A0F6SI48
names: Subcellular Location Annotation
messages: Periplasm

927083:DB32 RS09350
gene id: 927083:DB32_RS09350
uniprot id: A0A0F6W1C0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

927083:DB32 RS20345
gene id: 927083:DB32_RS20345
uniprot id: A0A0F6W446
names: Similarity
messages: Belongs to the asparagine synthetase family.

927083:DB32 RS34715
gene id: 927083:DB32_RS34715
uniprot id: A0A0F6W8A5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS06335
gene id: 927083:DB32_RS06335
uniprot id: A0A0F6W092
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS07250
gene id: 927083:DB32_RS07250
uniprot id: A0A0F6YG31
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

927083:DB32 RS21150
gene id: 927083:DB32_RS21150
uniprot id: A0A0F6W4L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

927083:DB32 RS13310
gene id: 927083:DB32_RS13310
uniprot id: A0A0F6YHW5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

927083:DB32 RS22000
gene id: 927083:DB32_RS22000
uniprot id: A0A0F6YIT3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

927083:DB32 RS24755
gene id: 927083:DB32_RS24755
uniprot id: A0A0F6W5F5
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

927083:DB32 RS23640
gene id: 927083:DB32_RS23640
uniprot id: A0A0F6W5B6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

927083:DB32 RS06445
gene id: 927083:DB32_RS06445
uniprot id: A0A0F6YGX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS37380
gene id: 927083:DB32_RS37380
uniprot id: A0A0F6W942
names: Similarity
messages: Belongs to the MoaD family.

927083:DB32 RS46780
gene id: 927083:DB32_RS46780
uniprot id: A0A0F6YIM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

927083:DB32 RS25575
gene id: 927083:DB32_RS25575
uniprot id: A0A0F6W5W7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

927083:DB32 RS09765
gene id: 927083:DB32_RS09765
uniprot id: A0A0F6YHM3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

927083:DB32 RS16325
gene id: 927083:DB32_RS16325
uniprot id: A0A0F6SF23
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

927083:DB32 RS34960
gene id: 927083:DB32_RS34960
uniprot id: A0A0F6W8C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

927083:DB32 RS24895
gene id: 927083:DB32_RS24895
uniprot id: A0A0F6W5I8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

927083:DB32 RS07490
gene id: 927083:DB32_RS07490
uniprot id: A0A0F6SE11
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

927083:DB32 RS06085
gene id: 927083:DB32_RS06085
uniprot id: A0A0F6SDV2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

927083:DB32 RS42195
gene id: 927083:DB32_RS42195
uniprot id: A0A0F6SI26
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

927083:DB32 RS25815
gene id: 927083:DB32_RS25815
uniprot id: A0A0F6W5R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

927083:DB32 RS03790
gene id: 927083:DB32_RS03790
uniprot id: A0A0F6SDK6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS10265
gene id: 927083:DB32_RS10265
uniprot id: A0A0F6SEC5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

927083:DB32 RS36335
gene id: 927083:DB32_RS36335
uniprot id: A0A0F6YM45
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS48650
gene id: 927083:DB32_RS48650
uniprot id: A0A0F6W6Z2
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS27190
gene id: 927083:DB32_RS27190
uniprot id: A0A0F6W6A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

927083:DB32 RS38220
gene id: 927083:DB32_RS38220
uniprot id: A0A0F6SHL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

927083:DB32 RS09325
gene id: 927083:DB32_RS09325
uniprot id: A0A0F6YHK3
names: Similarity
messages: Belongs to the peptidase M16 family.

927083:DB32 RS27050
gene id: 927083:DB32_RS27050
uniprot id: A0A0F6W641
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

927083:DB32 RS17715
gene id: 927083:DB32_RS17715
uniprot id: A0A0F6SF79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

927083:DB32 RS40450
gene id: 927083:DB32_RS40450
uniprot id: A0A0F6W9Y1
names: Similarity
messages: Belongs to the GST superfamily.

927083:DB32 RS19625
gene id: 927083:DB32_RS19625
uniprot id: A0A0F6W3X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

927083:DB32 RS18180
gene id: 927083:DB32_RS18180
uniprot id: A0A0F6YJV0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

927083:DB32 RS09330
gene id: 927083:DB32_RS09330
uniprot id: A0A0F6W142
names: Similarity
messages: Belongs to the peptidase M16 family.

927083:DB32 RS23655
gene id: 927083:DB32_RS23655
uniprot id: A0A0F6W553
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

927083:DB32 RS19860
gene id: 927083:DB32_RS19860
uniprot id: A0A0F6W439
names: Similarity
messages: Belongs to the aspartokinase family.

927083:DB32 RS23260
gene id: 927083:DB32_RS23260
uniprot id: A0A0F6W513
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

927083:DB32 RS24460
gene id: 927083:DB32_RS24460
uniprot id: A0A0F6YJA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

927083:DB32 RS04895
gene id: 927083:DB32_RS04895
uniprot id: A0A0F6VZU3
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

927083:DB32 RS04050
gene id: 927083:DB32_RS04050
uniprot id: A0A0F6SDL7
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

927083:DB32 RS05480
gene id: 927083:DB32_RS05480
uniprot id: A0A0F6SDS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

927083:DB32 RS00380
gene id: 927083:DB32_RS00380
uniprot id: A0A0F6VYU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

927083:DB32 RS26420
gene id: 927083:DB32_RS26420
uniprot id: A0A0F6SG84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

927083:DB32 RS20230
gene id: 927083:DB32_RS20230
uniprot id: A0A0F6SFI1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

927083:DB32 RS36900
gene id: 927083:DB32_RS36900
uniprot id: A0A0F6W8X8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

927083:DB32 RS14575
gene id: 927083:DB32_RS14575
uniprot id: A0A0F6YI69
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS05710
gene id: 927083:DB32_RS05710
uniprot id: A0A0F6W017
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

927083:DB32 RS04015
gene id: 927083:DB32_RS04015
uniprot id: A0A0F6YFJ9
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

927083:DB32 RS43145
gene id: 927083:DB32_RS43145
uniprot id: A0A0F6WAL4
names: Similarity
messages: Belongs to the peptidase A24 family.

927083:DB32 RS38225
gene id: 927083:DB32_RS38225
uniprot id: A0A0F6YNM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

927083:DB32 RS13930
gene id: 927083:DB32_RS13930
uniprot id: A0A0F6W2N2
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS19035
gene id: 927083:DB32_RS19035
uniprot id: A0A0F6YIJ4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

927083:DB32 RS41365
gene id: 927083:DB32_RS41365
uniprot id: A0A0F6SHZ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

927083:DB32 RS42610
gene id: 927083:DB32_RS42610
uniprot id: A0A0F6YMN1
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

927083:DB32 RS40765
gene id: 927083:DB32_RS40765
uniprot id: A0A0F6SHW8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

927083:DB32 RS15385
gene id: 927083:DB32_RS15385
uniprot id: A0A0F6W2Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

927083:DB32 RS00345
gene id: 927083:DB32_RS00345
uniprot id: A0A0F6YFP4
names: Similarity
messages: Belongs to the BMP lipoprotein family.

927083:DB32 RS36705
gene id: 927083:DB32_RS36705
uniprot id: A0A0F6YMG8
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS33990
gene id: 927083:DB32_RS33990
uniprot id: A0A0F6SH46
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS39875
gene id: 927083:DB32_RS39875
uniprot id: A0A0F6YMQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

927083:DB32 RS21445
gene id: 927083:DB32_RS21445
uniprot id: A0A0F6YJE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

927083:DB32 RS29720
gene id: 927083:DB32_RS29720
uniprot id: A0A0F6YKL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

927083:DB32 RS22750
gene id: 927083:DB32_RS22750
uniprot id: A0A0F6YJ44
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

927083:DB32 RS04925
gene id: 927083:DB32_RS04925
uniprot id: A0A0F6SDQ4
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS16850
gene id: 927083:DB32_RS16850
uniprot id: A0A0F6YIY3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

927083:DB32 RS42095
gene id: 927083:DB32_RS42095
uniprot id: A0A0F6YPG2
names: Similarity
messages: Belongs to the isochorismate synthase family.

927083:DB32 RS19930
gene id: 927083:DB32_RS19930
uniprot id: A0A0F6SFG9
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS42455
gene id: 927083:DB32_RS42455
uniprot id: A0A0F6SI37
names: Similarity
messages: Belongs to the malate synthase family.

927083:DB32 RS17365
gene id: 927083:DB32_RS17365
uniprot id: A0A0F6W3A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

927083:DB32 RS20555
gene id: 927083:DB32_RS20555
uniprot id: A0A0F6W467
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

927083:DB32 RS12440
gene id: 927083:DB32_RS12440
uniprot id: A0A0F6YHS4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

927083:DB32 RS00865
gene id: 927083:DB32_RS00865
uniprot id: A0A0F6YFZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

927083:DB32 RS26360
gene id: 927083:DB32_RS26360
uniprot id: A0A0F6W5T4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

927083:DB32 RS13290
gene id: 927083:DB32_RS13290
uniprot id: A0A0F6YI68
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS43735
gene id: 927083:DB32_RS43735
uniprot id: A0A0F6WAW0
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS32620
gene id: 927083:DB32_RS32620
uniprot id: A0A0F6W7V4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

927083:DB32 RS12575
gene id: 927083:DB32_RS12575
uniprot id: A0A0F6W208
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

927083:DB32 RS34025
gene id: 927083:DB32_RS34025
uniprot id: A0A0F6W849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

927083:DB32 RS47620
gene id: 927083:DB32_RS47620
uniprot id: A0A0F6YMA3
names: Subcellular Location Annotation
messages: Cytoplasm

927083:DB32 RS20220
gene id: 927083:DB32_RS20220
uniprot id: A0A0F6YJ71
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS35650
gene id: 927083:DB32_RS35650
uniprot id: A0A0F6SHB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

927083:DB32 RS33290
gene id: 927083:DB32_RS33290
uniprot id: A0A0F6W802
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

927083:DB32 RS01265
gene id: 927083:DB32_RS01265
uniprot id: A0A0F6SDA6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

927083:DB32 RS23005
gene id: 927083:DB32_RS23005
uniprot id: A0A0F6SFU3
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

927083:DB32 RS13700
gene id: 927083:DB32_RS13700
uniprot id: A0A0F6W2C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

927083:DB32 RS30260
gene id: 927083:DB32_RS30260
uniprot id: A0A0F6YKQ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

927083:DB32 RS24505
gene id: 927083:DB32_RS24505
uniprot id: A0A0F6SG05
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS10310
gene id: 927083:DB32_RS10310
uniprot id: A0A0F6YHQ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

927083:DB32 RS06300
gene id: 927083:DB32_RS06300
uniprot id: A0A0F6YGW5
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS00375
gene id: 927083:DB32_RS00375
uniprot id: A0A0F6YGJ3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

927083:DB32 RS42890
gene id: 927083:DB32_RS42890
uniprot id: A0A0F6SI55
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS08760
gene id: 927083:DB32_RS08760
uniprot id: A0A0F6W0V6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS25750
gene id: 927083:DB32_RS25750
uniprot id: A0A0F6W5Q8
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

927083:DB32 RS11705
gene id: 927083:DB32_RS11705
uniprot id: A0A0F6SEI4
names: Similarity
messages: Belongs to the asparaginase 1 family.

927083:DB32 RS39440
gene id: 927083:DB32_RS39440
uniprot id: A0A0F6SHR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

927083:DB32 RS16540
gene id: 927083:DB32_RS16540
uniprot id: A0A0F6YHV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

927083:DB32 RS13260
gene id: 927083:DB32_RS13260
uniprot id: A0A0F6YIW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

927083:DB32 RS21870
gene id: 927083:DB32_RS21870
uniprot id: A0A0F6W4L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

927083:DB32 RS33995
gene id: 927083:DB32_RS33995
uniprot id: A0A0F6YLS1
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS01635
gene id: 927083:DB32_RS01635
uniprot id: A0A0F6YGS4
names: Similarity
messages: Belongs to the AHA1 family.

927083:DB32 RS27900
gene id: 927083:DB32_RS27900
uniprot id: A0A0F6W6D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

927083:DB32 RS31280
gene id: 927083:DB32_RS31280
uniprot id: A0A0F6W7B5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

927083:DB32 RS35690
gene id: 927083:DB32_RS35690
uniprot id: A0A0F6W8J7
names: Similarity
messages: Belongs to the pirin family.

927083:DB32 RS01115
gene id: 927083:DB32_RS01115
uniprot id: A0A0F6VZ15
names: Similarity
messages: Belongs to the serpin family.

927083:DB32 RS14780
gene id: 927083:DB32_RS14780
uniprot id: A0A0F6W2V0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

927083:DB32 RS23355
gene id: 927083:DB32_RS23355
uniprot id: A0A0F6W4Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

927083:DB32 RS38655
gene id: 927083:DB32_RS38655
uniprot id: A0A0F6YN04
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

927083:DB32 RS21910
gene id: 927083:DB32_RS21910
uniprot id: A0A0F6YJH2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

927083:DB32 RS38210
gene id: 927083:DB32_RS38210
uniprot id: A0A0F6W988
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

927083:DB32 RS15890
gene id: 927083:DB32_RS15890
uniprot id: A0A0F6W2X7
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

927083:DB32 RS33470
gene id: 927083:DB32_RS33470
uniprot id: A0A0F6W7X7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

927083:DB32 RS18880
gene id: 927083:DB32_RS18880
uniprot id: A0A0F6SFC6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

927083:DB32 RS19990
gene id: 927083:DB32_RS19990
uniprot id: A0A0F6W451
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

927083:DB32 RS08010
gene id: 927083:DB32_RS08010
uniprot id: A0A0F6W0N3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

927083:DB32 RS49710
gene id: 927083:DB32_RS49710
uniprot id: A0A0F6YKG4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

927083:DB32 RS42030
gene id: 927083:DB32_RS42030
uniprot id: A0A0F6YMU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

927083:DB32 RS08440
gene id: 927083:DB32_RS08440
uniprot id: A0A0F6W0S3
names: Similarity
messages: Belongs to the transglycosylase Slt family.

927083:DB32 RS36955
gene id: 927083:DB32_RS36955
uniprot id: A0A0F6SHG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

927083:DB32 RS15130
gene id: 927083:DB32_RS15130
uniprot id: A0A0F6W2X3
names: Similarity
messages: Belongs to the TPP enzyme family.

927083:DB32 RS19080
gene id: 927083:DB32_RS19080
uniprot id: A0A0F6W3T4
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

927083:DB32 RS29095
gene id: 927083:DB32_RS29095
uniprot id: A0A0F6W6W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

927083:DB32 RS07830
gene id: 927083:DB32_RS07830
uniprot id: A0A0F6YH21
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

927083:DB32 RS18795
gene id: 927083:DB32_RS18795
uniprot id: A0A0F6W3U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

927083:DB32 RS01590
gene id: 927083:DB32_RS01590
uniprot id: A0A0F6VYY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

927083:DB32 RS39635
gene id: 927083:DB32_RS39635
uniprot id: A0A0F6YMP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

927083:DB32 RS34525
gene id: 927083:DB32_RS34525
uniprot id: A0A0F6YM59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

927083:DB32 RS04285
gene id: 927083:DB32_RS04285
uniprot id: A0A0F6YGI2
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS24615
gene id: 927083:DB32_RS24615
uniprot id: A0A0F6W5K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

927083:DB32 RS19265
gene id: 927083:DB32_RS19265
uniprot id: A0A0F6W3U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

927083:DB32 RS08575
gene id: 927083:DB32_RS08575
uniprot id: A0A0F6W0W9
names: Similarity
messages: Belongs to the Gfa family.

927083:DB32 RS07150
gene id: 927083:DB32_RS07150
uniprot id: A0A0F6W0S2
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS29670
gene id: 927083:DB32_RS29670
uniprot id: A0A0F6W6Q8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

927083:DB32 RS10300
gene id: 927083:DB32_RS10300
uniprot id: A0A0F6W1E3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS02275
gene id: 927083:DB32_RS02275
uniprot id: A0A0F6VZC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

927083:DB32 RS38955
gene id: 927083:DB32_RS38955
uniprot id: A0A0F6SHP3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

927083:DB32 RS20970
gene id: 927083:DB32_RS20970
uniprot id: A0A0F6W4J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

927083:DB32 RS25805
gene id: 927083:DB32_RS25805
uniprot id: A0A0F6W5Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

927083:DB32 RS38915
gene id: 927083:DB32_RS38915
uniprot id: A0A0F6YNV4
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS38190
gene id: 927083:DB32_RS38190
uniprot id: A0A0F6YMD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

927083:DB32 RS43385
gene id: 927083:DB32_RS43385
uniprot id: A0A0F6WAN7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

927083:DB32 RS25085
gene id: 927083:DB32_RS25085
uniprot id: A0A0F6YJM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-binding monooxygenase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

927083:DB32 RS49135
gene id: 927083:DB32_RS49135
uniprot id: A0A0F6W5H9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

927083:DB32 RS01430
gene id: 927083:DB32_RS01430
uniprot id: A0A0F6SDB3
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS34580
gene id: 927083:DB32_RS34580
uniprot id: A0A0F6YLI7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

927083:DB32 RS41535
gene id: 927083:DB32_RS41535
uniprot id: A0A0F6YMG2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

927083:DB32 RS05995
gene id: 927083:DB32_RS05995
uniprot id: A0A0F6W0D4
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

927083:DB32 RS18710
gene id: 927083:DB32_RS18710
uniprot id: A0A0F6SFB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

927083:DB32 RS33355
gene id: 927083:DB32_RS33355
uniprot id: A0A0F6YKX2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

927083:DB32 RS41825
gene id: 927083:DB32_RS41825
uniprot id: A0A0F6WA89
names: Similarity
messages: Belongs to the GST superfamily.

927083:DB32 RS41570
gene id: 927083:DB32_RS41570
uniprot id: A0A0F6YMR6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

927083:DB32 RS48210
gene id: 927083:DB32_RS48210
uniprot id: A0A0F6SEV0
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

927083:DB32 RS40970
gene id: 927083:DB32_RS40970
uniprot id: A0A0F6W9Y9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS16000
gene id: 927083:DB32_RS16000
uniprot id: A0A0F6SF10
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS01785
gene id: 927083:DB32_RS01785
uniprot id: A0A0F6VZ79
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

927083:DB32 RS38310
gene id: 927083:DB32_RS38310
uniprot id: A0A0F6SHL6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

927083:DB32 RS10900
gene id: 927083:DB32_RS10900
uniprot id: A0A0F6YHT2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

927083:DB32 RS43820
gene id: 927083:DB32_RS43820
uniprot id: A0A0F6WAW8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

927083:DB32 RS04980
gene id: 927083:DB32_RS04980
uniprot id: A0A0F6YFQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

927083:DB32 RS22395
gene id: 927083:DB32_RS22395
uniprot id: A0A0F6W4T3
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS19760
gene id: 927083:DB32_RS19760
uniprot id: A0A0F6W488
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

927083:DB32 RS09245
gene id: 927083:DB32_RS09245
uniprot id: A0A0F6W111
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

927083:DB32 RS35185
gene id: 927083:DB32_RS35185
uniprot id: A0A0F6W8E5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

927083:DB32 RS39985
gene id: 927083:DB32_RS39985
uniprot id: A0A0F6W9R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

927083:DB32 RS22570
gene id: 927083:DB32_RS22570
uniprot id: A0A0F6YKM3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

927083:DB32 RS06075
gene id: 927083:DB32_RS06075
uniprot id: A0A0F6W055
names: Similarity
messages: Belongs to the GSP E family.

927083:DB32 RS05940
gene id: 927083:DB32_RS05940
uniprot id: A0A0F6SDU6
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS39865
gene id: 927083:DB32_RS39865
uniprot id: A0A0F6W9Q2
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS42390
gene id: 927083:DB32_RS42390
uniprot id: A0A0F6YML8
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

927083:DB32 RS47185
gene id: 927083:DB32_RS47185
uniprot id: A0A0F6W6F7
names: Similarity
messages: Belongs to the universal stress protein A family.

927083:DB32 RS23735
gene id: 927083:DB32_RS23735
uniprot id: A0A0F6YK51
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

927083:DB32 RS36185
gene id: 927083:DB32_RS36185
uniprot id: A0A0F6W8K7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

927083:DB32 RS18970
gene id: 927083:DB32_RS18970
uniprot id: A0A0F6YJ90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

927083:DB32 RS40345
gene id: 927083:DB32_RS40345
uniprot id: A0A0F6YP44
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS16305
gene id: 927083:DB32_RS16305
uniprot id: A0A0F6W3A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

927083:DB32 RS26705
gene id: 927083:DB32_RS26705
uniprot id: A0A0F6SG96
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS38325
gene id: 927083:DB32_RS38325
uniprot id: A0A0F6W964
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

927083:DB32 RS15505
gene id: 927083:DB32_RS15505
uniprot id: A0A0F6W311
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

927083:DB32 RS36245
gene id: 927083:DB32_RS36245
uniprot id: A0A0F6W8Q3
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS04005
gene id: 927083:DB32_RS04005
uniprot id: A0A0F6VZL9
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

927083:DB32 RS05830
gene id: 927083:DB32_RS05830
uniprot id: A0A0F6W029
names: Similarity
messages: Belongs to the SCO1/2 family.

927083:DB32 RS13045
gene id: 927083:DB32_RS13045
uniprot id: A0A0F6YHV1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

927083:DB32 RS32475
gene id: 927083:DB32_RS32475
uniprot id: A0A0F6SGY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

927083:DB32 RS18800
gene id: 927083:DB32_RS18800
uniprot id: A0A0F6W3R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

927083:DB32 RS25280
gene id: 927083:DB32_RS25280
uniprot id: A0A0F6W5M3
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

927083:DB32 RS32430
gene id: 927083:DB32_RS32430
uniprot id: A0A0F6YKR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

927083:DB32 RS18325
gene id: 927083:DB32_RS18325
uniprot id: A0A0F6YJV7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

927083:DB32 RS25775
gene id: 927083:DB32_RS25775
uniprot id: A0A0F6W5Y3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

927083:DB32 RS16050
gene id: 927083:DB32_RS16050
uniprot id: A0A0F6SF12
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

927083:DB32 RS04600
gene id: 927083:DB32_RS04600
uniprot id: A0A0F6SDP0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

927083:DB32 RS31060
gene id: 927083:DB32_RS31060
uniprot id: A0A0F6W7G1
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS20320
gene id: 927083:DB32_RS20320
uniprot id: A0A0F6YIG3
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS16395
gene id: 927083:DB32_RS16395
uniprot id: A0A0F6W319
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS08340
gene id: 927083:DB32_RS08340
uniprot id: A0A0F6W0R5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS41055
gene id: 927083:DB32_RS41055
uniprot id: A0A0F6WA16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

927083:DB32 RS10005
gene id: 927083:DB32_RS10005
uniprot id: A0A0F6W1K5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

927083:DB32 RS29255
gene id: 927083:DB32_RS29255
uniprot id: A0A0F6SGK1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS20730
gene id: 927083:DB32_RS20730
uniprot id: A0A0F6W486
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

927083:DB32 RS20265
gene id: 927083:DB32_RS20265
uniprot id: A0A0F6YIP9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

927083:DB32 RS41465
gene id: 927083:DB32_RS41465
uniprot id: A0A0F6SHZ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

927083:DB32 RS16240
gene id: 927083:DB32_RS16240
uniprot id: A0A0F6YI05
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

927083:DB32 RS04680
gene id: 927083:DB32_RS04680
uniprot id: A0A0F6W018
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

927083:DB32 RS11175
gene id: 927083:DB32_RS11175
uniprot id: A0A0F6YGW3
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

927083:DB32 RS22515
gene id: 927083:DB32_RS22515
uniprot id: A0A0F6YJU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

927083:DB32 RS31400
gene id: 927083:DB32_RS31400
uniprot id: A0A0F6W7J2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

927083:DB32 RS20895
gene id: 927083:DB32_RS20895
uniprot id: A0A0F6W4A1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS40310
gene id: 927083:DB32_RS40310
uniprot id: A0A0F6SHU9
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS02500
gene id: 927083:DB32_RS02500
uniprot id: A0A0F6VZE7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

927083:DB32 RS13140
gene id: 927083:DB32_RS13140
uniprot id: A0A0F6W2F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

927083:DB32 RS05075
gene id: 927083:DB32_RS05075
uniprot id: A0A0F6VZW1
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS37195
gene id: 927083:DB32_RS37195
uniprot id: A0A0F6W8Z7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

927083:DB32 RS12680
gene id: 927083:DB32_RS12680
uniprot id: A0A0F6W2B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

927083:DB32 RS08230
gene id: 927083:DB32_RS08230
uniprot id: A0A0F6YGC4
names: Similarity
messages: Belongs to the type III secretion exporter family.

927083:DB32 RS06620
gene id: 927083:DB32_RS06620
uniprot id: A0A0F6W0D6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

927083:DB32 RS18235
gene id: 927083:DB32_RS18235
uniprot id: A0A0F6SFA0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

927083:DB32 RS04405
gene id: 927083:DB32_RS04405
uniprot id: A0A0F6SDN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

927083:DB32 RS27455
gene id: 927083:DB32_RS27455
uniprot id: A0A0F6YKR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

927083:DB32 RS31025
gene id: 927083:DB32_RS31025
uniprot id: A0A0F6SGS3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

927083:DB32 RS27905
gene id: 927083:DB32_RS27905
uniprot id: A0A0F6W6A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

927083:DB32 RS38120
gene id: 927083:DB32_RS38120
uniprot id: A0A0F6SHK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

927083:DB32 RS23430
gene id: 927083:DB32_RS23430
uniprot id: A0A0F6YK32
names: Similarity
messages: Belongs to the peptidase M24B family.

927083:DB32 RS33675
gene id: 927083:DB32_RS33675
uniprot id: A0A0F6YLD0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

927083:DB32 RS42430
gene id: 927083:DB32_RS42430
uniprot id: A0A0F6SI36
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS48050
gene id: 927083:DB32_RS48050
uniprot id: A0A0F6SE68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

927083:DB32 RS37405
gene id: 927083:DB32_RS37405
uniprot id: A0A0F6YM92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

927083:DB32 RS10415
gene id: 927083:DB32_RS10415
uniprot id: A0A0F6YGR0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

927083:DB32 RS18790
gene id: 927083:DB32_RS18790
uniprot id: A0A0F6YJY0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

927083:DB32 RS38100
gene id: 927083:DB32_RS38100
uniprot id: A0A0F6YMR7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

927083:DB32 RS23310
gene id: 927083:DB32_RS23310
uniprot id: A0A0F6W585
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

927083:DB32 RS40690
gene id: 927083:DB32_RS40690
uniprot id: A0A0F6YMV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

927083:DB32 RS19535
gene id: 927083:DB32_RS19535
uniprot id: A0A0F6W3X0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

927083:DB32 RS38460
gene id: 927083:DB32_RS38460
uniprot id: A0A0F6YLW7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

927083:DB32 RS36580
gene id: 927083:DB32_RS36580
uniprot id: A0A0F6W8V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

927083:DB32 RS16555
gene id: 927083:DB32_RS16555
uniprot id: A0A0F6YJL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

927083:DB32 RS41860
gene id: 927083:DB32_RS41860
uniprot id: A0A0F6WA79
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

927083:DB32 RS06785
gene id: 927083:DB32_RS06785
uniprot id: A0A0F6YFZ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS10020
gene id: 927083:DB32_RS10020
uniprot id: A0A0F6W1C3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

927083:DB32 RS14500
gene id: 927083:DB32_RS14500
uniprot id: A0A0F6W2H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

927083:DB32 RS15535
gene id: 927083:DB32_RS15535
uniprot id: A0A0F6W314
names: Similarity
messages: Belongs to the HesB/IscA family.

927083:DB32 RS16575
gene id: 927083:DB32_RS16575
uniprot id: A0A0F6W362
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

927083:DB32 RS06390
gene id: 927083:DB32_RS06390
uniprot id: A0A0F6W096
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

927083:DB32 RS14085
gene id: 927083:DB32_RS14085
uniprot id: A0A0F6SET2
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

927083:DB32 RS07895
gene id: 927083:DB32_RS07895
uniprot id: A0A0F6SE27
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

927083:DB32 RS19020
gene id: 927083:DB32_RS19020
uniprot id: A0A0F6YJZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

927083:DB32 RS37290
gene id: 927083:DB32_RS37290
uniprot id: A0A0F6W933
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

927083:DB32 RS05470
gene id: 927083:DB32_RS05470
uniprot id: A0A0F6VZZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

927083:DB32 RS22095
gene id: 927083:DB32_RS22095
uniprot id: A0A0F6SFQ7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

927083:DB32 RS20070
gene id: 927083:DB32_RS20070
uniprot id: A0A0F6YJ62
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

927083:DB32 RS16525
gene id: 927083:DB32_RS16525
uniprot id: A0A0F6YIL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

927083:DB32 RS36735
gene id: 927083:DB32_RS36735
uniprot id: A0A0F6SHF3
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS34250
gene id: 927083:DB32_RS34250
uniprot id: A0A0F6YN07
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS02540
gene id: 927083:DB32_RS02540
uniprot id: A0A0F6VZ75
names: Function
names: Similarity
messages: Belongs to the LuxC family.
messages: LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.

927083:DB32 RS32765
gene id: 927083:DB32_RS32765
uniprot id: A0A0F6W7L7
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

927083:DB32 RS38140
gene id: 927083:DB32_RS38140
uniprot id: A0A0F6YNM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

927083:DB32 RS11355
gene id: 927083:DB32_RS11355
uniprot id: A0A0F6W1X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

927083:DB32 RS13115
gene id: 927083:DB32_RS13115
uniprot id: A0A0F6YI56
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

927083:DB32 RS42165
gene id: 927083:DB32_RS42165
uniprot id: A0A0F6YMK4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

927083:DB32 RS23715
gene id: 927083:DB32_RS23715
uniprot id: A0A0F6W529
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS47945
gene id: 927083:DB32_RS47945
uniprot id: A0A0F6VZW4
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS27435
gene id: 927083:DB32_RS27435
uniprot id: A0A0F6SGC6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

927083:DB32 RS14255
gene id: 927083:DB32_RS14255
uniprot id: A0A0F6W2F2
names: Similarity
messages: Belongs to the fabD family.

927083:DB32 RS41155
gene id: 927083:DB32_RS41155
uniprot id: A0A0F6YMB6
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

927083:DB32 RS25820
gene id: 927083:DB32_RS25820
uniprot id: A0A0F6SG59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

927083:DB32 RS31865
gene id: 927083:DB32_RS31865
uniprot id: A0A0F6W7G2
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS39375
gene id: 927083:DB32_RS39375
uniprot id: A0A0F6SHR0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS21755
gene id: 927083:DB32_RS21755
uniprot id: A0A0F6SFP3
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS05935
gene id: 927083:DB32_RS05935
uniprot id: A0A0F6W0C8
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

927083:DB32 RS13135
gene id: 927083:DB32_RS13135
uniprot id: A0A0F6YHV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

927083:DB32 RS16145
gene id: 927083:DB32_RS16145
uniprot id: A0A0F6W393
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

927083:DB32 RS39195
gene id: 927083:DB32_RS39195
uniprot id: A0A0F6YML2
names: Similarity
messages: Belongs to the YciI family.

927083:DB32 RS25700
gene id: 927083:DB32_RS25700
uniprot id: A0A0F6YJR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

927083:DB32 RS31395
gene id: 927083:DB32_RS31395
uniprot id: A0A0F6YMH3
names: Similarity
messages: Belongs to the DprA/Smf family.

927083:DB32 RS27465
gene id: 927083:DB32_RS27465
uniprot id: A0A0F6W6D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

927083:DB32 RS07735
gene id: 927083:DB32_RS07735
uniprot id: A0A0F6YH65
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

927083:DB32 RS42080
gene id: 927083:DB32_RS42080
uniprot id: A0A0F6YMJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

927083:DB32 RS14125
gene id: 927083:DB32_RS14125
uniprot id: A0A0F6W2G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

927083:DB32 RS03335
gene id: 927083:DB32_RS03335
uniprot id: A0A0F6VZL0
names: Similarity
messages: Belongs to the AHA1 family.

927083:DB32 RS12275
gene id: 927083:DB32_RS12275
uniprot id: A0A0F6SEK8
names: Subcellular Location Annotation
messages: Cytoplasm

927083:DB32 RS14260
gene id: 927083:DB32_RS14260
uniprot id: A0A0F6YIC8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS14070
gene id: 927083:DB32_RS14070
uniprot id: A0A0F6W2G3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

927083:DB32 RS13765
gene id: 927083:DB32_RS13765
uniprot id: A0A0F6W2A2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

927083:DB32 RS25885
gene id: 927083:DB32_RS25885
uniprot id: A0A0F6YKB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

927083:DB32 RS06735
gene id: 927083:DB32_RS06735
uniprot id: A0A0F6W0C1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS19350
gene id: 927083:DB32_RS19350
uniprot id: A0A0F6SFE5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

927083:DB32 RS25760
gene id: 927083:DB32_RS25760
uniprot id: A0A0F6YLA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

927083:DB32 RS42025
gene id: 927083:DB32_RS42025
uniprot id: A0A0F6WAD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

927083:DB32 RS09135
gene id: 927083:DB32_RS09135
uniprot id: A0A0F6W128
names: Similarity
messages: Belongs to the thioredoxin family.

927083:DB32 RS20425
gene id: 927083:DB32_RS20425
uniprot id: A0A0F6YIQ7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

927083:DB32 RS02315
gene id: 927083:DB32_RS02315
uniprot id: A0A0F6SDF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

927083:DB32 RS32815
gene id: 927083:DB32_RS32815
uniprot id: A0A0F6W7X0
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

927083:DB32 RS43455
gene id: 927083:DB32_RS43455
uniprot id: A0A0F6YMT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

927083:DB32 RS18565
gene id: 927083:DB32_RS18565
uniprot id: A0A0F6YJW9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

927083:DB32 RS12395
gene id: 927083:DB32_RS12395
uniprot id: A0A0F6W1X4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

927083:DB32 RS20225
gene id: 927083:DB32_RS20225
uniprot id: A0A0F6W4D3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

927083:DB32 RS04030
gene id: 927083:DB32_RS04030
uniprot id: A0A0F6YH67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS03690
gene id: 927083:DB32_RS03690
uniprot id: A0A0F6VZH4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

927083:DB32 RS10860
gene id: 927083:DB32_RS10860
uniprot id: A0A0F6W1G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

927083:DB32 RS01360
gene id: 927083:DB32_RS01360
uniprot id: A0A0F6SDB0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

927083:DB32 RS18440
gene id: 927083:DB32_RS18440
uniprot id: A0A0F6YJ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

927083:DB32 RS15985
gene id: 927083:DB32_RS15985
uniprot id: A0A0F6YHS6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

927083:DB32 RS29690
gene id: 927083:DB32_RS29690
uniprot id: A0A0F6YK60
names: Similarity
messages: Belongs to the UPF0111 family.

927083:DB32 RS13235
gene id: 927083:DB32_RS13235
uniprot id: A0A0F6W285
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

927083:DB32 RS09640
gene id: 927083:DB32_RS09640
uniprot id: A0A0F6YHA3
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS40840
gene id: 927083:DB32_RS40840
uniprot id: A0A0F6W9X6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

927083:DB32 RS27945
gene id: 927083:DB32_RS27945
uniprot id: A0A0F6SGE7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

927083:DB32 RS29125
gene id: 927083:DB32_RS29125
uniprot id: A0A0F6W6W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

927083:DB32 RS43805
gene id: 927083:DB32_RS43805
uniprot id: A0A0F6WAT2
names: Similarity
messages: Belongs to the AHA1 family.

927083:DB32 RS42925
gene id: 927083:DB32_RS42925
uniprot id: A0A0F6WAJ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

927083:DB32 RS38040
gene id: 927083:DB32_RS38040
uniprot id: A0A0F6W9A0
names: Similarity
messages: Belongs to the acylphosphatase family.

927083:DB32 RS05235
gene id: 927083:DB32_RS05235
uniprot id: A0A0F6YFN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

927083:DB32 RS16945
gene id: 927083:DB32_RS16945
uniprot id: A0A0F6YHX4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

927083:DB32 RS02550
gene id: 927083:DB32_RS02550
uniprot id: A0A0F6VZ67
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

927083:DB32 RS05145
gene id: 927083:DB32_RS05145
uniprot id: A0A0F6SDR3
names: Similarity
messages: Belongs to the CmpA/NrtA family.

927083:DB32 RS08740
gene id: 927083:DB32_RS08740
uniprot id: A0A0F6SE62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

927083:DB32 RS29705
gene id: 927083:DB32_RS29705
uniprot id: A0A0F6W6R1
names: Similarity
messages: Belongs to the Lgt family.

927083:DB32 RS36345
gene id: 927083:DB32_RS36345
uniprot id: A0A0F6W8T8
names: Similarity
messages: Belongs to the peptidase U62 family.

927083:DB32 RS38090
gene id: 927083:DB32_RS38090
uniprot id: A0A0F6W940
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

927083:DB32 RS18660
gene id: 927083:DB32_RS18660
uniprot id: A0A0F6SFB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

927083:DB32 RS48750
gene id: 927083:DB32_RS48750
uniprot id: A0A0F6YLL1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS13280
gene id: 927083:DB32_RS13280
uniprot id: A0A0F6YHE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS20835
gene id: 927083:DB32_RS20835
uniprot id: A0A0F6W4I9
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

927083:DB32 RS23475
gene id: 927083:DB32_RS23475
uniprot id: A0A0F6SFW3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

927083:DB32 RS20985
gene id: 927083:DB32_RS20985
uniprot id: A0A0F6W4E6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

927083:DB32 RS05080
gene id: 927083:DB32_RS05080
uniprot id: A0A0F6VZV4
names: Subcellular Location Annotation
messages: Membrane

927083:DB32 RS08655
gene id: 927083:DB32_RS08655
uniprot id: A0A0F6W151
names: Similarity
messages: Belongs to the citrate synthase family.

927083:DB32 RS08650
gene id: 927083:DB32_RS08650
uniprot id: A0A0F6YHE6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

927083:DB32 RS43785
gene id: 927083:DB32_RS43785
uniprot id: A0A0F6YN38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

927083:DB32 RS20020
gene id: 927083:DB32_RS20020
uniprot id: A0A0F6W4B2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

927083:DB32 RS19025
gene id: 927083:DB32_RS19025
uniprot id: A0A0F6SFD2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

927083:DB32 RS12725
gene id: 927083:DB32_RS12725
uniprot id: A0A0F6W244
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane