906968:TREBR RS11215
gene id: 906968:TREBR_RS11215
uniprot id: F4LKN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

906968:TREBR RS00915
gene id: 906968:TREBR_RS00915
uniprot id: F4LLU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS11995
gene id: 906968:TREBR_RS11995
uniprot id: F4LM67
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

906968:TREBR RS12855
gene id: 906968:TREBR_RS12855
uniprot id: F4LNE4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

906968:TREBR RS07440
gene id: 906968:TREBR_RS07440
uniprot id: F4LNN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

906968:TREBR RS11125
gene id: 906968:TREBR_RS11125
uniprot id: F4LKL4
names: Similarity
messages: Belongs to the thioredoxin family.

906968:TREBR RS05710
gene id: 906968:TREBR_RS05710
uniprot id: F4LKH2
names: Similarity
messages: Belongs to the peptidase S1C family.

906968:TREBR RS12545
gene id: 906968:TREBR_RS12545
uniprot id: F4LMV1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

906968:TREBR RS11590
gene id: 906968:TREBR_RS11590
uniprot id: F4LL79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS07610
gene id: 906968:TREBR_RS07610
uniprot id: F4LNR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

906968:TREBR RS09175
gene id: 906968:TREBR_RS09175
uniprot id: F4LQJ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

906968:TREBR RS06000
gene id: 906968:TREBR_RS06000
uniprot id: F4LL02
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

906968:TREBR RS09590
gene id: 906968:TREBR_RS09590
uniprot id: F4LIW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasmic flagellum

906968:TREBR RS02465
gene id: 906968:TREBR_RS02465
uniprot id: F4LP55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

906968:TREBR RS02685
gene id: 906968:TREBR_RS02685
uniprot id: F4LPF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

906968:TREBR RS06995
gene id: 906968:TREBR_RS06995
uniprot id: F4LMP1
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

906968:TREBR RS04885
gene id: 906968:TREBR_RS04885
uniprot id: F4LJJ7
names: Similarity
messages: Belongs to the DprA/Smf family.

906968:TREBR RS02335
gene id: 906968:TREBR_RS02335
uniprot id: F4LP31
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

906968:TREBR RS09985
gene id: 906968:TREBR_RS09985
uniprot id: F4LJA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

906968:TREBR RS05095
gene id: 906968:TREBR_RS05095
uniprot id: F4LJV3
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS05395
gene id: 906968:TREBR_RS05395
uniprot id: F4LKB1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

906968:TREBR RS03305
gene id: 906968:TREBR_RS03305
uniprot id: F4LQ69
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

906968:TREBR RS09320
gene id: 906968:TREBR_RS09320
uniprot id: F4LIJ9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

906968:TREBR RS11455
gene id: 906968:TREBR_RS11455
uniprot id: F4LL54
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

906968:TREBR RS00920
gene id: 906968:TREBR_RS00920
uniprot id: F4LLU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS11075
gene id: 906968:TREBR_RS11075
uniprot id: F4LKK4
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS11030
gene id: 906968:TREBR_RS11030
uniprot id: F4LKJ5
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS06890
gene id: 906968:TREBR_RS06890
uniprot id: F4LMM1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

906968:TREBR RS11980
gene id: 906968:TREBR_RS11980
uniprot id: F4LLT6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

906968:TREBR RS00025
gene id: 906968:TREBR_RS00025
uniprot id: F4LK77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

906968:TREBR RS00520
gene id: 906968:TREBR_RS00520
uniprot id: F4LKV1
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

906968:TREBR RS01210
gene id: 906968:TREBR_RS01210
uniprot id: F4LMD4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

906968:TREBR RS00015
gene id: 906968:TREBR_RS00015
uniprot id: F4LK74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

906968:TREBR RS02945
gene id: 906968:TREBR_RS02945
uniprot id: F4LPS8
names: Similarity
messages: Belongs to the DEAD box helicase family.

906968:TREBR RS13375
gene id: 906968:TREBR_RS13375
uniprot id: F4LLY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

906968:TREBR RS11870
gene id: 906968:TREBR_RS11870
uniprot id: F4LLR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

906968:TREBR RS02855
gene id: 906968:TREBR_RS02855
uniprot id: F4LPJ2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS02100
gene id: 906968:TREBR_RS02100
uniprot id: F4LNK8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

906968:TREBR RS04685
gene id: 906968:TREBR_RS04685
uniprot id: F4LJG1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

906968:TREBR RS10260
gene id: 906968:TREBR_RS10260
uniprot id: F4LJM4
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

906968:TREBR RS00170
gene id: 906968:TREBR_RS00170
uniprot id: F4LKA4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

906968:TREBR RS04335
gene id: 906968:TREBR_RS04335
uniprot id: F4LIW1
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

906968:TREBR RS05745
gene id: 906968:TREBR_RS05745
uniprot id: F4LKV6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

906968:TREBR RS06910
gene id: 906968:TREBR_RS06910
uniprot id: F4LMM5
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS05995
gene id: 906968:TREBR_RS05995
uniprot id: F4LL01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

906968:TREBR RS11745
gene id: 906968:TREBR_RS11745
uniprot id: F4LLP2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

906968:TREBR RS04840
gene id: 906968:TREBR_RS04840
uniprot id: F4LJI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

906968:TREBR RS08295
gene id: 906968:TREBR_RS08295
uniprot id: F4LPN8
names: Subcellular Location Annotation
messages: Nucleus

906968:TREBR RS00320
gene id: 906968:TREBR_RS00320
uniprot id: F4LKR2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

906968:TREBR RS04120
gene id: 906968:TREBR_RS04120
uniprot id: F4LIS1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

906968:TREBR RS10545
gene id: 906968:TREBR_RS10545
uniprot id: F4LJT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

906968:TREBR RS05410
gene id: 906968:TREBR_RS05410
uniprot id: F4LKB4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

906968:TREBR RS04845
gene id: 906968:TREBR_RS04845
uniprot id: F4LJI9
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS10630
gene id: 906968:TREBR_RS10630
uniprot id: F4LK15
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

906968:TREBR RS08300
gene id: 906968:TREBR_RS08300
uniprot id: F4LPN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

906968:TREBR RS07630
gene id: 906968:TREBR_RS07630
uniprot id: F4LNS2
names: Similarity
messages: Belongs to the Fur family.

906968:TREBR RS11300
gene id: 906968:TREBR_RS11300
uniprot id: F4LL27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

906968:TREBR RS05075
gene id: 906968:TREBR_RS05075
uniprot id: F4LJU9
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS12760
gene id: 906968:TREBR_RS12760
uniprot id: F4LNC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

906968:TREBR RS08150
gene id: 906968:TREBR_RS08150
uniprot id: F4LPL0
names: Similarity
messages: Belongs to the Skp family.

906968:TREBR RS13620
gene id: 906968:TREBR_RS13620
uniprot id: F4LM46
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS00845
gene id: 906968:TREBR_RS00845
uniprot id: F4LLE8
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS11735
gene id: 906968:TREBR_RS11735
uniprot id: F4LLP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

906968:TREBR RS10655
gene id: 906968:TREBR_RS10655
uniprot id: F4LK20
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

906968:TREBR RS10425
gene id: 906968:TREBR_RS10425
uniprot id: F4LJQ6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

906968:TREBR RS07195
gene id: 906968:TREBR_RS07195
uniprot id: F4LN61
names: Similarity
messages: Belongs to the CapA family.

906968:TREBR RS06250
gene id: 906968:TREBR_RS06250
uniprot id: F4LLI4
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

906968:TREBR RS12330
gene id: 906968:TREBR_RS12330
uniprot id: F4LMD2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

906968:TREBR RS05180
gene id: 906968:TREBR_RS05180
uniprot id: F4LJW8
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

906968:TREBR RS01260
gene id: 906968:TREBR_RS01260
uniprot id: F4LME4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

906968:TREBR RS05555
gene id: 906968:TREBR_RS05555
uniprot id: F4LKE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

906968:TREBR RS00750
gene id: 906968:TREBR_RS00750
uniprot id: F4LLD0
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

906968:TREBR RS08725
gene id: 906968:TREBR_RS08725
uniprot id: F4LQ40
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

906968:TREBR RS11730
gene id: 906968:TREBR_RS11730
uniprot id: F4LLN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

906968:TREBR RS12320
gene id: 906968:TREBR_RS12320
uniprot id: F4LMD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

906968:TREBR RS11390
gene id: 906968:TREBR_RS11390
uniprot id: F4LL44
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

906968:TREBR RS01430
gene id: 906968:TREBR_RS01430
uniprot id: F4LMH7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

906968:TREBR RS13305
gene id: 906968:TREBR_RS13305
uniprot id: F4LP12
names: Similarity
messages: Belongs to the acetyltransferase family. ArgA subfamily.

906968:TREBR RS09165
gene id: 906968:TREBR_RS09165
uniprot id: F4LQJ0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

906968:TREBR RS10170
gene id: 906968:TREBR_RS10170
uniprot id: F4LJE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

906968:TREBR RS03200
gene id: 906968:TREBR_RS03200
uniprot id: F4LPX7
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

906968:TREBR RS02180
gene id: 906968:TREBR_RS02180
uniprot id: F4LNM4
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS08185
gene id: 906968:TREBR_RS08185
uniprot id: F4LPL7
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

906968:TREBR RS11850
gene id: 906968:TREBR_RS11850
uniprot id: F4LLR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

906968:TREBR RS07740
gene id: 906968:TREBR_RS07740
uniprot id: F4LNU2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

906968:TREBR RS10875
gene id: 906968:TREBR_RS10875
uniprot id: F4LK63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

906968:TREBR RS07540
gene id: 906968:TREBR_RS07540
uniprot id: F4LNQ7
names: Similarity
messages: Belongs to the UPF0758 family.

906968:TREBR RS12160
gene id: 906968:TREBR_RS12160
uniprot id: F4LM99
names: Similarity
messages: Belongs to the peptidase M29 family.

906968:TREBR RS01735
gene id: 906968:TREBR_RS01735
uniprot id: F4LN12
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

906968:TREBR RS06445
gene id: 906968:TREBR_RS06445
uniprot id: F4LM08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS02360
gene id: 906968:TREBR_RS02360
uniprot id: F4LP36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS00275
gene id: 906968:TREBR_RS00275
uniprot id: F4LKQ2
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

906968:TREBR RS02955
gene id: 906968:TREBR_RS02955
uniprot id: F4LPT0
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

906968:TREBR RS11580
gene id: 906968:TREBR_RS11580
uniprot id: F4LL77
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

906968:TREBR RS12970
gene id: 906968:TREBR_RS12970
uniprot id: F4LNG8
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

906968:TREBR RS10150
gene id: 906968:TREBR_RS10150
uniprot id: F4LJD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

906968:TREBR RS10505
gene id: 906968:TREBR_RS10505
uniprot id: F4LJS2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

906968:TREBR RS08690
gene id: 906968:TREBR_RS08690
uniprot id: F4LQ33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

906968:TREBR RS06755
gene id: 906968:TREBR_RS06755
uniprot id: F4LM65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

906968:TREBR RS08255
gene id: 906968:TREBR_RS08255
uniprot id: F4LPN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

906968:TREBR RS02645
gene id: 906968:TREBR_RS02645
uniprot id: F4LPF0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

906968:TREBR RS06090
gene id: 906968:TREBR_RS06090
uniprot id: F4LLF3
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS10315
gene id: 906968:TREBR_RS10315
uniprot id: F4LJN4
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS04510
gene id: 906968:TREBR_RS04510
uniprot id: F4LJ65
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

906968:TREBR RS09455
gene id: 906968:TREBR_RS09455
uniprot id: F4LIM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

906968:TREBR RS05025
gene id: 906968:TREBR_RS05025
uniprot id: F4LJU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

906968:TREBR RS09750
gene id: 906968:TREBR_RS09750
uniprot id: F4LIZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

906968:TREBR RS03645
gene id: 906968:TREBR_RS03645
uniprot id: F4LIB6
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS11070
gene id: 906968:TREBR_RS11070
uniprot id: F4LKK3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

906968:TREBR RS08420
gene id: 906968:TREBR_RS08420
uniprot id: F4LPR3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

906968:TREBR RS11800
gene id: 906968:TREBR_RS11800
uniprot id: F4LLQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

906968:TREBR RS00955
gene id: 906968:TREBR_RS00955
uniprot id: F4LLV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

906968:TREBR RS09115
gene id: 906968:TREBR_RS09115
uniprot id: F4LQI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

906968:TREBR RS04230
gene id: 906968:TREBR_RS04230
uniprot id: F4LIU3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

906968:TREBR RS10700
gene id: 906968:TREBR_RS10700
uniprot id: F4LK28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

906968:TREBR RS12150
gene id: 906968:TREBR_RS12150
uniprot id: F4LM97
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

906968:TREBR RS02445
gene id: 906968:TREBR_RS02445
uniprot id: F4LP51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

906968:TREBR RS04900
gene id: 906968:TREBR_RS04900
uniprot id: F4LJK0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

906968:TREBR RS04815
gene id: 906968:TREBR_RS04815
uniprot id: F4LJI3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

906968:TREBR RS06580
gene id: 906968:TREBR_RS06580
uniprot id: F4LM30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

906968:TREBR RS03995
gene id: 906968:TREBR_RS03995
uniprot id: F4LIP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane
messages: Membrane

906968:TREBR RS11835
gene id: 906968:TREBR_RS11835
uniprot id: F4LLR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

906968:TREBR RS05635
gene id: 906968:TREBR_RS05635
uniprot id: F4LKF8
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

906968:TREBR RS10470
gene id: 906968:TREBR_RS10470
uniprot id: F4LJR5
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

906968:TREBR RS00005
gene id: 906968:TREBR_RS00005
uniprot id: F4LK72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

906968:TREBR RS08810
gene id: 906968:TREBR_RS08810
uniprot id: F4LQ56
names: Similarity
messages: Belongs to the citrate synthase family.

906968:TREBR RS02630
gene id: 906968:TREBR_RS02630
uniprot id: F4LPE7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

906968:TREBR RS05315
gene id: 906968:TREBR_RS05315
uniprot id: F4LJZ2
names: Similarity
messages: Belongs to the peptidase S33 family.

906968:TREBR RS11890
gene id: 906968:TREBR_RS11890
uniprot id: F4LLS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

906968:TREBR RS00240
gene id: 906968:TREBR_RS00240
uniprot id: F4LKP5
names: Function
names: Subunit
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

906968:TREBR RS00925
gene id: 906968:TREBR_RS00925
uniprot id: F4LLU9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

906968:TREBR RS06075
gene id: 906968:TREBR_RS06075
uniprot id: F4LL17
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

906968:TREBR RS04355
gene id: 906968:TREBR_RS04355
uniprot id: F4LJ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

906968:TREBR RS01050
gene id: 906968:TREBR_RS01050
uniprot id: F4LLX4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

906968:TREBR RS03900
gene id: 906968:TREBR_RS03900
uniprot id: F4LIG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

906968:TREBR RS01760
gene id: 906968:TREBR_RS01760
uniprot id: F4LN17
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

906968:TREBR RS07325
gene id: 906968:TREBR_RS07325
uniprot id: F4LN87
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

906968:TREBR RS06895
gene id: 906968:TREBR_RS06895
uniprot id: F4LMM2
names: Similarity
messages: Belongs to the threonine synthase family.

906968:TREBR RS06070
gene id: 906968:TREBR_RS06070
uniprot id: F4LL16
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

906968:TREBR RS14640
gene id: 906968:TREBR_RS14640
uniprot id: F4LL09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

906968:TREBR RS07555
gene id: 906968:TREBR_RS07555
uniprot id: F4LNR0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

906968:TREBR RS11610
gene id: 906968:TREBR_RS11610
uniprot id: F4LL83
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

906968:TREBR RS11660
gene id: 906968:TREBR_RS11660
uniprot id: F4LLM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

906968:TREBR RS06380
gene id: 906968:TREBR_RS06380
uniprot id: F4LLK9
names: Similarity
messages: Belongs to the Fur family.

906968:TREBR RS11810
gene id: 906968:TREBR_RS11810
uniprot id: F4LLQ6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

906968:TREBR RS03815
gene id: 906968:TREBR_RS03815
uniprot id: F4LIE8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

906968:TREBR RS05525
gene id: 906968:TREBR_RS05525
uniprot id: F4LKD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

906968:TREBR RS00575
gene id: 906968:TREBR_RS00575
uniprot id: F4LL95
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

906968:TREBR RS03605
gene id: 906968:TREBR_RS03605
uniprot id: F4LQC8
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS00225
gene id: 906968:TREBR_RS00225
uniprot id: F4LKP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS02150
gene id: 906968:TREBR_RS02150
uniprot id: F4LNL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS08910
gene id: 906968:TREBR_RS08910
uniprot id: F4LQE5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

906968:TREBR RS06110
gene id: 906968:TREBR_RS06110
uniprot id: F4LLF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

906968:TREBR RS01935
gene id: 906968:TREBR_RS01935
uniprot id: F4LNH9
names: Similarity
messages: Belongs to the catalase family.

906968:TREBR RS12235
gene id: 906968:TREBR_RS12235
uniprot id: F4LMB3
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

906968:TREBR RS03310
gene id: 906968:TREBR_RS03310
uniprot id: F4LQ70
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

906968:TREBR RS04530
gene id: 906968:TREBR_RS04530
uniprot id: F4LJ68
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS09960
gene id: 906968:TREBR_RS09960
uniprot id: F4LJA2
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

906968:TREBR RS08730
gene id: 906968:TREBR_RS08730
uniprot id: F4LQ41
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

906968:TREBR RS09760
gene id: 906968:TREBR_RS09760
uniprot id: F4LIZ8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

906968:TREBR RS05385
gene id: 906968:TREBR_RS05385
uniprot id: F4LK03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

906968:TREBR RS03240
gene id: 906968:TREBR_RS03240
uniprot id: F4LPY5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

906968:TREBR RS09570
gene id: 906968:TREBR_RS09570
uniprot id: F4LIW2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

906968:TREBR RS09720
gene id: 906968:TREBR_RS09720
uniprot id: F4LIZ0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS03850
gene id: 906968:TREBR_RS03850
uniprot id: F4LIF4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

906968:TREBR RS04585
gene id: 906968:TREBR_RS04585
uniprot id: F4LJ79
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

906968:TREBR RS01315
gene id: 906968:TREBR_RS01315
uniprot id: F4LMF5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

906968:TREBR RS09725
gene id: 906968:TREBR_RS09725
uniprot id: F4LIZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

906968:TREBR RS00855
gene id: 906968:TREBR_RS00855
uniprot id: F4LLF0
names: Function
names: Similarity
messages: Belongs to the acyltransferase CrtO family.
messages: Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i.e. the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin. This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains.

906968:TREBR RS12955
gene id: 906968:TREBR_RS12955
uniprot id: F4LNG5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS02010
gene id: 906968:TREBR_RS02010
uniprot id: F4LNJ3
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS04270
gene id: 906968:TREBR_RS04270
uniprot id: F4LIU9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

906968:TREBR RS11325
gene id: 906968:TREBR_RS11325
uniprot id: F4LL32
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS07870
gene id: 906968:TREBR_RS07870
uniprot id: F4LP91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

906968:TREBR RS03685
gene id: 906968:TREBR_RS03685
uniprot id: F4LIC4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

906968:TREBR RS07910
gene id: 906968:TREBR_RS07910
uniprot id: F4LP98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

906968:TREBR RS07210
gene id: 906968:TREBR_RS07210
uniprot id: F4LN64
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS05085
gene id: 906968:TREBR_RS05085
uniprot id: F4LJV1
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS03980
gene id: 906968:TREBR_RS03980
uniprot id: F4LIH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

906968:TREBR RS10165
gene id: 906968:TREBR_RS10165
uniprot id: F4LJE1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

906968:TREBR RS12260
gene id: 906968:TREBR_RS12260
uniprot id: F4LMB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

906968:TREBR RS03555
gene id: 906968:TREBR_RS03555
uniprot id: F4LQB8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

906968:TREBR RS05560
gene id: 906968:TREBR_RS05560
uniprot id: F4LKE3
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS13510
gene id: 906968:TREBR_RS13510
uniprot id: F4LIH1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

906968:TREBR RS08610
gene id: 906968:TREBR_RS08610
uniprot id: F4LQ18
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

906968:TREBR RS12455
gene id: 906968:TREBR_RS12455
uniprot id: F4LMT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

906968:TREBR RS06950
gene id: 906968:TREBR_RS06950
uniprot id: F4LMN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

906968:TREBR RS02890
gene id: 906968:TREBR_RS02890
uniprot id: F4LPJ9
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS03155
gene id: 906968:TREBR_RS03155
uniprot id: F4LPW8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

906968:TREBR RS09620
gene id: 906968:TREBR_RS09620
uniprot id: F4LIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

906968:TREBR RS02095
gene id: 906968:TREBR_RS02095
uniprot id: F4LNK7
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

906968:TREBR RS05485
gene id: 906968:TREBR_RS05485
uniprot id: F4LIJ9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

906968:TREBR RS06390
gene id: 906968:TREBR_RS06390
uniprot id: F4LLL1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

906968:TREBR RS02825
gene id: 906968:TREBR_RS02825
uniprot id: F4LPI6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

906968:TREBR RS08165
gene id: 906968:TREBR_RS08165
uniprot id: F4LPL3
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

906968:TREBR RS06550
gene id: 906968:TREBR_RS06550
uniprot id: F4LM24
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

906968:TREBR RS02635
gene id: 906968:TREBR_RS02635
uniprot id: F4LPE8
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

906968:TREBR RS12385
gene id: 906968:TREBR_RS12385
uniprot id: F4LMR9
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS07615
gene id: 906968:TREBR_RS07615
uniprot id: F4LNR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

906968:TREBR RS03070
gene id: 906968:TREBR_RS03070
uniprot id: F4LPV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

906968:TREBR RS09915
gene id: 906968:TREBR_RS09915
uniprot id: F4LJ29
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

906968:TREBR RS04045
gene id: 906968:TREBR_RS04045
uniprot id: F4LIQ6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

906968:TREBR RS03145
gene id: 906968:TREBR_RS03145
uniprot id: F4LPW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

906968:TREBR RS02130
gene id: 906968:TREBR_RS02130
uniprot id: F4LNL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS08635
gene id: 906968:TREBR_RS08635
uniprot id: F4LQ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS02525
gene id: 906968:TREBR_RS02525
uniprot id: F4LP61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

906968:TREBR RS10075
gene id: 906968:TREBR_RS10075
uniprot id: F4LJC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

906968:TREBR RS11840
gene id: 906968:TREBR_RS11840
uniprot id: F4LLR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

906968:TREBR RS09055
gene id: 906968:TREBR_RS09055
uniprot id: F4LQG9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

906968:TREBR RS07115
gene id: 906968:TREBR_RS07115
uniprot id: F4LN45
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

906968:TREBR RS09375
gene id: 906968:TREBR_RS09375
uniprot id: F4LIK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

906968:TREBR RS06970
gene id: 906968:TREBR_RS06970
uniprot id: F4LMN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS10435
gene id: 906968:TREBR_RS10435
uniprot id: F4LJQ8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

906968:TREBR RS09485
gene id: 906968:TREBR_RS09485
uniprot id: F4LIM9
names: Subcellular Location Annotation
messages: Periplasmic flagellum

906968:TREBR RS02880
gene id: 906968:TREBR_RS02880
uniprot id: F4LPJ7
names: Similarity
messages: Belongs to the disproportionating enzyme family.

906968:TREBR RS12155
gene id: 906968:TREBR_RS12155
uniprot id: F4LM98
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

906968:TREBR RS13460
gene id: 906968:TREBR_RS13460
uniprot id: F4LP72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

906968:TREBR RS00110
gene id: 906968:TREBR_RS00110
uniprot id: F4LK93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS00185
gene id: 906968:TREBR_RS00185
uniprot id: F4LKA7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

906968:TREBR RS04305
gene id: 906968:TREBR_RS04305
uniprot id: F4LIV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

906968:TREBR RS05540
gene id: 906968:TREBR_RS05540
uniprot id: F4LKD9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

906968:TREBR RS13930
gene id: 906968:TREBR_RS13930
uniprot id: F4LMB4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS01630
gene id: 906968:TREBR_RS01630
uniprot id: F4LMZ1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

906968:TREBR RS13925
gene id: 906968:TREBR_RS13925
uniprot id: F4LMA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

906968:TREBR RS06570
gene id: 906968:TREBR_RS06570
uniprot id: F4LM28
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

906968:TREBR RS03990
gene id: 906968:TREBR_RS03990
uniprot id: F4LIH9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

906968:TREBR RS03015
gene id: 906968:TREBR_RS03015
uniprot id: F4LPU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

906968:TREBR RS11425
gene id: 906968:TREBR_RS11425
uniprot id: F4LL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

906968:TREBR RS13750
gene id: 906968:TREBR_RS13750
uniprot id: F4LQI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

906968:TREBR RS11830
gene id: 906968:TREBR_RS11830
uniprot id: F4LLR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

906968:TREBR RS13290
gene id: 906968:TREBR_RS13290
uniprot id: F4LP09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS06620
gene id: 906968:TREBR_RS06620
uniprot id: F4LM38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

906968:TREBR RS12440
gene id: 906968:TREBR_RS12440
uniprot id: F4LMT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

906968:TREBR RS02545
gene id: 906968:TREBR_RS02545
uniprot id: F4LP65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

906968:TREBR RS13310
gene id: 906968:TREBR_RS13310
uniprot id: F4LP13
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

906968:TREBR RS04835
gene id: 906968:TREBR_RS04835
uniprot id: F4LJI7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

906968:TREBR RS00445
gene id: 906968:TREBR_RS00445
uniprot id: F4LKT6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

906968:TREBR RS08270
gene id: 906968:TREBR_RS08270
uniprot id: F4LPN3
names: Similarity
messages: Belongs to the FlgD family.

906968:TREBR RS04540
gene id: 906968:TREBR_RS04540
uniprot id: F4LJ70
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS04615
gene id: 906968:TREBR_RS04615
uniprot id: F4LJ85
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

906968:TREBR RS04065
gene id: 906968:TREBR_RS04065
uniprot id: F4LIR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS08085
gene id: 906968:TREBR_RS08085
uniprot id: F4LPD3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

906968:TREBR RS08240
gene id: 906968:TREBR_RS08240
uniprot id: F4LPM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

906968:TREBR RS01280
gene id: 906968:TREBR_RS01280
uniprot id: F4LME8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

906968:TREBR RS11715
gene id: 906968:TREBR_RS11715
uniprot id: F4LLN5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

906968:TREBR RS01550
gene id: 906968:TREBR_RS01550
uniprot id: F4LMX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

906968:TREBR RS04500
gene id: 906968:TREBR_RS04500
uniprot id: F4LJ63
names: Similarity
messages: Belongs to the IMPACT family.

906968:TREBR RS07710
gene id: 906968:TREBR_RS07710
uniprot id: F4LNT6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

906968:TREBR RS03925
gene id: 906968:TREBR_RS03925
uniprot id: F4LIG8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

906968:TREBR RS01175
gene id: 906968:TREBR_RS01175
uniprot id: F4LLZ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

906968:TREBR RS07800
gene id: 906968:TREBR_RS07800
uniprot id: F4LP77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

906968:TREBR RS01610
gene id: 906968:TREBR_RS01610
uniprot id: F4LMY7
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

906968:TREBR RS04740
gene id: 906968:TREBR_RS04740
uniprot id: F4LJH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

906968:TREBR RS13955
gene id: 906968:TREBR_RS13955
uniprot id: F4LNF8
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

906968:TREBR RS02345
gene id: 906968:TREBR_RS02345
uniprot id: F4LP33
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

906968:TREBR RS02925
gene id: 906968:TREBR_RS02925
uniprot id: F4LPK6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

906968:TREBR RS07330
gene id: 906968:TREBR_RS07330
uniprot id: F4LN88
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

906968:TREBR RS10765
gene id: 906968:TREBR_RS10765
uniprot id: F4LK41
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

906968:TREBR RS00460
gene id: 906968:TREBR_RS00460
uniprot id: F4LKT9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

906968:TREBR RS11290
gene id: 906968:TREBR_RS11290
uniprot id: F4LL25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

906968:TREBR RS08650
gene id: 906968:TREBR_RS08650
uniprot id: F4LQ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS02930
gene id: 906968:TREBR_RS02930
uniprot id: F4LPK7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

906968:TREBR RS07960
gene id: 906968:TREBR_RS07960
uniprot id: F4LPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Periplasm
messages: Periplasmic flagellum
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.

906968:TREBR RS08360
gene id: 906968:TREBR_RS08360
uniprot id: F4LPQ1
names: Similarity
messages: Belongs to the TrpF family.

906968:TREBR RS12885
gene id: 906968:TREBR_RS12885
uniprot id: F4LNF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

906968:TREBR RS07995
gene id: 906968:TREBR_RS07995
uniprot id: F4LPB5
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

906968:TREBR RS06095
gene id: 906968:TREBR_RS06095
uniprot id: F4LLF4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

906968:TREBR RS08160
gene id: 906968:TREBR_RS08160
uniprot id: F4LPL2
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS02660
gene id: 906968:TREBR_RS02660
uniprot id: F4LPF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

906968:TREBR RS07705
gene id: 906968:TREBR_RS07705
uniprot id: F4LNT5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

906968:TREBR RS13040
gene id: 906968:TREBR_RS13040
uniprot id: F4LNW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

906968:TREBR RS02145
gene id: 906968:TREBR_RS02145
uniprot id: F4LNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS08585
gene id: 906968:TREBR_RS08585
uniprot id: F4LQ13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS01320
gene id: 906968:TREBR_RS01320
uniprot id: F4LMF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

906968:TREBR RS05950
gene id: 906968:TREBR_RS05950
uniprot id: F4LKZ2
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

906968:TREBR RS03010
gene id: 906968:TREBR_RS03010
uniprot id: F4LPU0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

906968:TREBR RS10775
gene id: 906968:TREBR_RS10775
uniprot id: F4LK43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

906968:TREBR RS10155
gene id: 906968:TREBR_RS10155
uniprot id: F4LJD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

906968:TREBR RS03210
gene id: 906968:TREBR_RS03210
uniprot id: F4LPX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

906968:TREBR RS05650
gene id: 906968:TREBR_RS05650
uniprot id: F4LKG1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

906968:TREBR RS12740
gene id: 906968:TREBR_RS12740
uniprot id: F4LNC2
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS02560
gene id: 906968:TREBR_RS02560
uniprot id: F4LP68
names: Similarity
messages: Belongs to the UPF0237 family.

906968:TREBR RS01120
gene id: 906968:TREBR_RS01120
uniprot id: F4LLY8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

906968:TREBR RS09530
gene id: 906968:TREBR_RS09530
uniprot id: F4LIN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

906968:TREBR RS04990
gene id: 906968:TREBR_RS04990
uniprot id: F4LJL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

906968:TREBR RS03545
gene id: 906968:TREBR_RS03545
uniprot id: F4LQB6
names: Similarity
messages: Belongs to the fabD family.

906968:TREBR RS06130
gene id: 906968:TREBR_RS06130
uniprot id: F4LLG1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

906968:TREBR RS11465
gene id: 906968:TREBR_RS11465
uniprot id: F4LL56
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

906968:TREBR RS05535
gene id: 906968:TREBR_RS05535
uniprot id: F4LKD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

906968:TREBR RS01350
gene id: 906968:TREBR_RS01350
uniprot id: F4LMG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

906968:TREBR RS09270
gene id: 906968:TREBR_RS09270
uniprot id: F4LIJ1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

906968:TREBR RS06565
gene id: 906968:TREBR_RS06565
uniprot id: F4LM27
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS06400
gene id: 906968:TREBR_RS06400
uniprot id: F4LLL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

906968:TREBR RS01230
gene id: 906968:TREBR_RS01230
uniprot id: F4LMD8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS06680
gene id: 906968:TREBR_RS06680
uniprot id: F4LM50
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

906968:TREBR RS08355
gene id: 906968:TREBR_RS08355
uniprot id: F4LPQ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS06240
gene id: 906968:TREBR_RS06240
uniprot id: F4LLI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

906968:TREBR RS01940
gene id: 906968:TREBR_RS01940
uniprot id: F4LNI0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

906968:TREBR RS09540
gene id: 906968:TREBR_RS09540
uniprot id: F4LIP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

906968:TREBR RS06990
gene id: 906968:TREBR_RS06990
uniprot id: F4LMP0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

906968:TREBR RS09860
gene id: 906968:TREBR_RS09860
uniprot id: F4LJ18
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

906968:TREBR RS09865
gene id: 906968:TREBR_RS09865
uniprot id: F4LJ19
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

906968:TREBR RS02625
gene id: 906968:TREBR_RS02625
uniprot id: F4LPE6
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS10540
gene id: 906968:TREBR_RS10540
uniprot id: F4LJS9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

906968:TREBR RS07180
gene id: 906968:TREBR_RS07180
uniprot id: F4LN58
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS01075
gene id: 906968:TREBR_RS01075
uniprot id: F4LLX9
names: Similarity
messages: Belongs to the peptidase M16 family.

906968:TREBR RS04350
gene id: 906968:TREBR_RS04350
uniprot id: F4LJ32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

906968:TREBR RS02670
gene id: 906968:TREBR_RS02670
uniprot id: F4LPF5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

906968:TREBR RS11875
gene id: 906968:TREBR_RS11875
uniprot id: F4LLR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

906968:TREBR RS04595
gene id: 906968:TREBR_RS04595
uniprot id: F4LJ81
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

906968:TREBR RS02620
gene id: 906968:TREBR_RS02620
uniprot id: F4LPE5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

906968:TREBR RS00685
gene id: 906968:TREBR_RS00685
uniprot id: F4LLB7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

906968:TREBR RS04245
gene id: 906968:TREBR_RS04245
uniprot id: F4LIU5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

906968:TREBR RS04865
gene id: 906968:TREBR_RS04865
uniprot id: F4LJJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

906968:TREBR RS10055
gene id: 906968:TREBR_RS10055
uniprot id: F4LJB9
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS00450
gene id: 906968:TREBR_RS00450
uniprot id: F4LKT7
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS11825
gene id: 906968:TREBR_RS11825
uniprot id: F4LLQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

906968:TREBR RS07515
gene id: 906968:TREBR_RS07515
uniprot id: F4LNQ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

906968:TREBR RS00010
gene id: 906968:TREBR_RS00010
uniprot id: F4LK73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

906968:TREBR RS11720
gene id: 906968:TREBR_RS11720
uniprot id: F4LLN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

906968:TREBR RS06015
gene id: 906968:TREBR_RS06015
uniprot id: F4LL05
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

906968:TREBR RS10025
gene id: 906968:TREBR_RS10025
uniprot id: F4LJB4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

906968:TREBR RS02615
gene id: 906968:TREBR_RS02615
uniprot id: F4LPE4
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS00660
gene id: 906968:TREBR_RS00660
uniprot id: F4LLB2
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

906968:TREBR RS10120
gene id: 906968:TREBR_RS10120
uniprot id: F4LJD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

906968:TREBR RS11845
gene id: 906968:TREBR_RS11845
uniprot id: F4LLR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

906968:TREBR RS07280
gene id: 906968:TREBR_RS07280
uniprot id: F4LN78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

906968:TREBR RS11445
gene id: 906968:TREBR_RS11445
uniprot id: F4LL52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

906968:TREBR RS00440
gene id: 906968:TREBR_RS00440
uniprot id: F4LKT5
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

906968:TREBR RS09585
gene id: 906968:TREBR_RS09585
uniprot id: F4LIW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

906968:TREBR RS04400
gene id: 906968:TREBR_RS04400
uniprot id: F4LJ42
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

906968:TREBR RS10005
gene id: 906968:TREBR_RS10005
uniprot id: F4LJB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

906968:TREBR RS08450
gene id: 906968:TREBR_RS08450
uniprot id: F4LPR9
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

906968:TREBR RS03325
gene id: 906968:TREBR_RS03325
uniprot id: F4LQ73
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

906968:TREBR RS07340
gene id: 906968:TREBR_RS07340
uniprot id: F4LN90
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS13005
gene id: 906968:TREBR_RS13005
uniprot id: F4LNV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS08115
gene id: 906968:TREBR_RS08115
uniprot id: F4LPD7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

906968:TREBR RS06820
gene id: 906968:TREBR_RS06820
uniprot id: F4LIJ9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

906968:TREBR RS07300
gene id: 906968:TREBR_RS07300
uniprot id: F4LN82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

906968:TREBR RS06470
gene id: 906968:TREBR_RS06470
uniprot id: F4LM13
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS01310
gene id: 906968:TREBR_RS01310
uniprot id: F4LMF4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

906968:TREBR RS11110
gene id: 906968:TREBR_RS11110
uniprot id: F4LKL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
messages: Monomer.

906968:TREBR RS13315
gene id: 906968:TREBR_RS13315
uniprot id: F4LP14
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

906968:TREBR RS01090
gene id: 906968:TREBR_RS01090
uniprot id: F4LLY2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

906968:TREBR RS07215
gene id: 906968:TREBR_RS07215
uniprot id: F4LN65
names: Similarity
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.

906968:TREBR RS02125
gene id: 906968:TREBR_RS02125
uniprot id: F4LNL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS07220
gene id: 906968:TREBR_RS07220
uniprot id: F4LN66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

906968:TREBR RS03410
gene id: 906968:TREBR_RS03410
uniprot id: F4LQ90
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

906968:TREBR RS02405
gene id: 906968:TREBR_RS02405
uniprot id: F4LP45
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

906968:TREBR RS13350
gene id: 906968:TREBR_RS13350
uniprot id: F4LLE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

906968:TREBR RS02655
gene id: 906968:TREBR_RS02655
uniprot id: F4LPF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

906968:TREBR RS11340
gene id: 906968:TREBR_RS11340
uniprot id: F4LL35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

906968:TREBR RS04980
gene id: 906968:TREBR_RS04980
uniprot id: F4LJL6
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS03195
gene id: 906968:TREBR_RS03195
uniprot id: F4LPX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

906968:TREBR RS03505
gene id: 906968:TREBR_RS03505
uniprot id: F4LQA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS12815
gene id: 906968:TREBR_RS12815
uniprot id: F4LND6
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

906968:TREBR RS11025
gene id: 906968:TREBR_RS11025
uniprot id: F4LKJ4
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS13105
gene id: 906968:TREBR_RS13105
uniprot id: F4LNX5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

906968:TREBR RS07975
gene id: 906968:TREBR_RS07975
uniprot id: F4LPB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

906968:TREBR RS13265
gene id: 906968:TREBR_RS13265
uniprot id: F4LP04
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS09810
gene id: 906968:TREBR_RS09810
uniprot id: F4LJ08
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS12800
gene id: 906968:TREBR_RS12800
uniprot id: F4LND3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS08705
gene id: 906968:TREBR_RS08705
uniprot id: F4LQ36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

906968:TREBR RS09855
gene id: 906968:TREBR_RS09855
uniprot id: F4LJ17
names: Function
names: Similarity
messages: Belongs to the bacterial histone-like protein family.
messages: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.

906968:TREBR RS11310
gene id: 906968:TREBR_RS11310
uniprot id: F4LL29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

906968:TREBR RS01290
gene id: 906968:TREBR_RS01290
uniprot id: F4LMF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

906968:TREBR RS06885
gene id: 906968:TREBR_RS06885
uniprot id: F4LMM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

906968:TREBR RS08605
gene id: 906968:TREBR_RS08605
uniprot id: F4LQ17
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

906968:TREBR RS09050
gene id: 906968:TREBR_RS09050
uniprot id: F4LQG8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

906968:TREBR RS00310
gene id: 906968:TREBR_RS00310
uniprot id: F4LKQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

906968:TREBR RS06160
gene id: 906968:TREBR_RS06160
uniprot id: F4LLG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

906968:TREBR RS09105
gene id: 906968:TREBR_RS09105
uniprot id: F4LQH9
names: Similarity
messages: Belongs to the peptidase S1C family.

906968:TREBR RS07315
gene id: 906968:TREBR_RS07315
uniprot id: F4LN85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

906968:TREBR RS09075
gene id: 906968:TREBR_RS09075
uniprot id: F4LQH3
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

906968:TREBR RS02795
gene id: 906968:TREBR_RS02795
uniprot id: F4LPI0
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

906968:TREBR RS02140
gene id: 906968:TREBR_RS02140
uniprot id: F4LNL6
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

906968:TREBR RS06360
gene id: 906968:TREBR_RS06360
uniprot id: F4LLK5
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS08900
gene id: 906968:TREBR_RS08900
uniprot id: F4LQE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

906968:TREBR RS07355
gene id: 906968:TREBR_RS07355
uniprot id: F4LN92
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS07415
gene id: 906968:TREBR_RS07415
uniprot id: F4LNA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS04805
gene id: 906968:TREBR_RS04805
uniprot id: F4LJI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

906968:TREBR RS07510
gene id: 906968:TREBR_RS07510
uniprot id: F4LNQ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

906968:TREBR RS00420
gene id: 906968:TREBR_RS00420
uniprot id: F4LKT1
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS04930
gene id: 906968:TREBR_RS04930
uniprot id: F4LJK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

906968:TREBR RS04920
gene id: 906968:TREBR_RS04920
uniprot id: F4LJK4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

906968:TREBR RS03335
gene id: 906968:TREBR_RS03335
uniprot id: F4LQ75
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

906968:TREBR RS05065
gene id: 906968:TREBR_RS05065
uniprot id: F4LJU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

906968:TREBR RS06670
gene id: 906968:TREBR_RS06670
uniprot id: F4LM48
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

906968:TREBR RS03805
gene id: 906968:TREBR_RS03805
uniprot id: F4LIE6
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

906968:TREBR RS05980
gene id: 906968:TREBR_RS05980
uniprot id: F4LKZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

906968:TREBR RS11355
gene id: 906968:TREBR_RS11355
uniprot id: F4LL38
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

906968:TREBR RS01955
gene id: 906968:TREBR_RS01955
uniprot id: F4LNI3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

906968:TREBR RS10270
gene id: 906968:TREBR_RS10270
uniprot id: F4LJM6
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

906968:TREBR RS05970
gene id: 906968:TREBR_RS05970
uniprot id: F4LKZ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

906968:TREBR RS14610
gene id: 906968:TREBR_RS14610
uniprot id: F4LPJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

906968:TREBR RS11795
gene id: 906968:TREBR_RS11795
uniprot id: F4LLQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

906968:TREBR RS08800
gene id: 906968:TREBR_RS08800
uniprot id: F4LQ54
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

906968:TREBR RS11955
gene id: 906968:TREBR_RS11955
uniprot id: F4LLT2
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS11710
gene id: 906968:TREBR_RS11710
uniprot id: F4LLN4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

906968:TREBR RS11240
gene id: 906968:TREBR_RS11240
uniprot id: F4LKN6
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

906968:TREBR RS11820
gene id: 906968:TREBR_RS11820
uniprot id: F4LLQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

906968:TREBR RS05625
gene id: 906968:TREBR_RS05625
uniprot id: F4LKF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

906968:TREBR RS02590
gene id: 906968:TREBR_RS02590
uniprot id: F4LP74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

906968:TREBR RS03690
gene id: 906968:TREBR_RS03690
uniprot id: F4LIC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

906968:TREBR RS12180
gene id: 906968:TREBR_RS12180
uniprot id: F4LMA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

906968:TREBR RS05700
gene id: 906968:TREBR_RS05700
uniprot id: F4LKH0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

906968:TREBR RS10390
gene id: 906968:TREBR_RS10390
uniprot id: F4LJP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS09310
gene id: 906968:TREBR_RS09310
uniprot id: F4LIJ8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

906968:TREBR RS02905
gene id: 906968:TREBR_RS02905
uniprot id: F4LPK2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

906968:TREBR RS02915
gene id: 906968:TREBR_RS02915
uniprot id: F4LPK4
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS04850
gene id: 906968:TREBR_RS04850
uniprot id: F4LJJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

906968:TREBR RS11065
gene id: 906968:TREBR_RS11065
uniprot id: F4LKK2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

906968:TREBR RS07530
gene id: 906968:TREBR_RS07530
uniprot id: F4LNQ5
names: Similarity
messages: Belongs to the UMP kinase family.

906968:TREBR RS01405
gene id: 906968:TREBR_RS01405
uniprot id: F4LMH2
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

906968:TREBR RS07345
gene id: 906968:TREBR_RS07345
uniprot id: F4LN91
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

906968:TREBR RS08735
gene id: 906968:TREBR_RS08735
uniprot id: F4LQ42
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

906968:TREBR RS11500
gene id: 906968:TREBR_RS11500
uniprot id: F4LL62
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS11450
gene id: 906968:TREBR_RS11450
uniprot id: F4LL53
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS00035
gene id: 906968:TREBR_RS00035
uniprot id: F4LK79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

906968:TREBR RS03045
gene id: 906968:TREBR_RS03045
uniprot id: F4LPU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS04825
gene id: 906968:TREBR_RS04825
uniprot id: F4LJI5
names: Subcellular Location Annotation
messages: Periplasmic flagellum

906968:TREBR RS09125
gene id: 906968:TREBR_RS09125
uniprot id: F4LQI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

906968:TREBR RS00675
gene id: 906968:TREBR_RS00675
uniprot id: F4LLB5
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS03520
gene id: 906968:TREBR_RS03520
uniprot id: F4LQB1
names: Similarity
messages: Belongs to the glutamine synthetase family.

906968:TREBR RS04345
gene id: 906968:TREBR_RS04345
uniprot id: F4LJ31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

906968:TREBR RS01865
gene id: 906968:TREBR_RS01865
uniprot id: F4LN34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

906968:TREBR RS10625
gene id: 906968:TREBR_RS10625
uniprot id: F4LK14
names: Similarity
messages: Belongs to the RutC family.

906968:TREBR RS07505
gene id: 906968:TREBR_RS07505
uniprot id: F4LNQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS05835
gene id: 906968:TREBR_RS05835
uniprot id: F4LKX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

906968:TREBR RS11635
gene id: 906968:TREBR_RS11635
uniprot id: F4LLL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

906968:TREBR RS08020
gene id: 906968:TREBR_RS08020
uniprot id: F4LPC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS01510
gene id: 906968:TREBR_RS01510
uniprot id: F4LMJ1
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

906968:TREBR RS14585
gene id: 906968:TREBR_RS14585
uniprot id: F4LNI6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

906968:TREBR RS09595
gene id: 906968:TREBR_RS09595
uniprot id: F4LIW7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

906968:TREBR RS04365
gene id: 906968:TREBR_RS04365
uniprot id: F4LJ35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

906968:TREBR RS06750
gene id: 906968:TREBR_RS06750
uniprot id: F4LM64
names: Similarity
messages: Belongs to the GSP E family.

906968:TREBR RS04050
gene id: 906968:TREBR_RS04050
uniprot id: F4LIQ7
names: Similarity
messages: Belongs to the YggT family.

906968:TREBR RS14600
gene id: 906968:TREBR_RS14600
uniprot id: F4LP17
names: Similarity
messages: Belongs to the sigma-54 factor family.

906968:TREBR RS10995
gene id: 906968:TREBR_RS10995
uniprot id: F4LKI9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

906968:TREBR RS13355
gene id: 906968:TREBR_RS13355
uniprot id: F4LLU3
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS13870
gene id: 906968:TREBR_RS13870
uniprot id: F4LL33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

906968:TREBR RS12220
gene id: 906968:TREBR_RS12220
uniprot id: F4LMB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS04905
gene id: 906968:TREBR_RS04905
uniprot id: F4LJK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

906968:TREBR RS12930
gene id: 906968:TREBR_RS12930
uniprot id: F4LNF9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

906968:TREBR RS01870
gene id: 906968:TREBR_RS01870
uniprot id: F4LN35
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

906968:TREBR RS08070
gene id: 906968:TREBR_RS08070
uniprot id: F4LPD0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

906968:TREBR RS10455
gene id: 906968:TREBR_RS10455
uniprot id: F4LJR2
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

906968:TREBR RS08400
gene id: 906968:TREBR_RS08400
uniprot id: F4LPQ9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

906968:TREBR RS11295
gene id: 906968:TREBR_RS11295
uniprot id: F4LL26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

906968:TREBR RS07935
gene id: 906968:TREBR_RS07935
uniprot id: F4LPA3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

906968:TREBR RS06080
gene id: 906968:TREBR_RS06080
uniprot id: F4LL18
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

906968:TREBR RS04610
gene id: 906968:TREBR_RS04610
uniprot id: F4LJ84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

906968:TREBR RS01990
gene id: 906968:TREBR_RS01990
uniprot id: F4LNJ0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS06370
gene id: 906968:TREBR_RS06370
uniprot id: F4LLK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

906968:TREBR RS06840
gene id: 906968:TREBR_RS06840
uniprot id: F4LIJ9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

906968:TREBR RS01720
gene id: 906968:TREBR_RS01720
uniprot id: F4LN09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS02610
gene id: 906968:TREBR_RS02610
uniprot id: F4LPE3
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS00090
gene id: 906968:TREBR_RS00090
uniprot id: F4LK89
names: Similarity
messages: Belongs to the UxaA family.

906968:TREBR RS05715
gene id: 906968:TREBR_RS05715
uniprot id: F4LKH3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

906968:TREBR RS00205
gene id: 906968:TREBR_RS00205
uniprot id: F4LKN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

906968:TREBR RS08235
gene id: 906968:TREBR_RS08235
uniprot id: F4LPM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

906968:TREBR RS10915
gene id: 906968:TREBR_RS10915
uniprot id: F4LK71
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

906968:TREBR RS05825
gene id: 906968:TREBR_RS05825
uniprot id: F4LKW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

906968:TREBR RS04910
gene id: 906968:TREBR_RS04910
uniprot id: F4LJK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

906968:TREBR RS12470
gene id: 906968:TREBR_RS12470
uniprot id: F4LMT6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

906968:TREBR RS08375
gene id: 906968:TREBR_RS08375
uniprot id: F4LPQ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

906968:TREBR RS06055
gene id: 906968:TREBR_RS06055
uniprot id: F4LL13
names: Similarity
messages: Belongs to the aldose epimerase family.

906968:TREBR RS09740
gene id: 906968:TREBR_RS09740
uniprot id: F4LIZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

906968:TREBR RS08200
gene id: 906968:TREBR_RS08200
uniprot id: F4LPL9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

906968:TREBR RS04855
gene id: 906968:TREBR_RS04855
uniprot id: F4LJJ1
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS11535
gene id: 906968:TREBR_RS11535
uniprot id: F4LIJ9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

906968:TREBR RS09520
gene id: 906968:TREBR_RS09520
uniprot id: F4LIN6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

906968:TREBR RS12780
gene id: 906968:TREBR_RS12780
uniprot id: F4LNC9
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS03710
gene id: 906968:TREBR_RS03710
uniprot id: F4LIC9
names: Similarity
messages: Belongs to the TPP enzyme family.

906968:TREBR RS00345
gene id: 906968:TREBR_RS00345
uniprot id: F4LKR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

906968:TREBR RS04940
gene id: 906968:TREBR_RS04940
uniprot id: F4LJK8
names: Subcellular Location Annotation
messages: Cytoplasm

906968:TREBR RS13285
gene id: 906968:TREBR_RS13285
uniprot id: F4LP08
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

906968:TREBR RS02015
gene id: 906968:TREBR_RS02015
uniprot id: F4LNJ4
names: Similarity
messages: Belongs to the GARS family.

906968:TREBR RS08915
gene id: 906968:TREBR_RS08915
uniprot id: F4LQE6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

906968:TREBR RS01300
gene id: 906968:TREBR_RS01300
uniprot id: F4LMF2
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS04915
gene id: 906968:TREBR_RS04915
uniprot id: F4LJK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

906968:TREBR RS10900
gene id: 906968:TREBR_RS10900
uniprot id: F4LK68
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

906968:TREBR RS07055
gene id: 906968:TREBR_RS07055
uniprot id: F4LMQ1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

906968:TREBR RS09780
gene id: 906968:TREBR_RS09780
uniprot id: F4LJ02
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

906968:TREBR RS12190
gene id: 906968:TREBR_RS12190
uniprot id: F4LMA5
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

906968:TREBR RS11865
gene id: 906968:TREBR_RS11865
uniprot id: F4LLR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

906968:TREBR RS03535
gene id: 906968:TREBR_RS03535
uniprot id: F4LQB4
names: Similarity
messages: Belongs to the asparagine synthetase family.

906968:TREBR RS07255
gene id: 906968:TREBR_RS07255
uniprot id: F4LN73
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

906968:TREBR RS01255
gene id: 906968:TREBR_RS01255
uniprot id: F4LME3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

906968:TREBR RS12445
gene id: 906968:TREBR_RS12445
uniprot id: F4LMT1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

906968:TREBR RS07865
gene id: 906968:TREBR_RS07865
uniprot id: F4LP90
names: Similarity
messages: Belongs to the Nth/MutY family.

906968:TREBR RS11640
gene id: 906968:TREBR_RS11640
uniprot id: F4LLL9
names: Similarity
messages: Belongs to the peptidase S41A family.

906968:TREBR RS01055
gene id: 906968:TREBR_RS01055
uniprot id: F4LLX5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

906968:TREBR RS00105
gene id: 906968:TREBR_RS00105
uniprot id: F4LK92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS03245
gene id: 906968:TREBR_RS03245
uniprot id: F4LPY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

906968:TREBR RS02920
gene id: 906968:TREBR_RS02920
uniprot id: F4LPK5
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS03725
gene id: 906968:TREBR_RS03725
uniprot id: F4LID2
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS03660
gene id: 906968:TREBR_RS03660
uniprot id: F4LIB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

906968:TREBR RS09900
gene id: 906968:TREBR_RS09900
uniprot id: F4LJ26
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

906968:TREBR RS01850
gene id: 906968:TREBR_RS01850
uniprot id: F4LN31
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

906968:TREBR RS10430
gene id: 906968:TREBR_RS10430
uniprot id: F4LJQ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS12185
gene id: 906968:TREBR_RS12185
uniprot id: F4LMA4
names: Similarity
messages: Belongs to the HisA/HisF family.

906968:TREBR RS10185
gene id: 906968:TREBR_RS10185
uniprot id: F4LJE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

906968:TREBR RS08755
gene id: 906968:TREBR_RS08755
uniprot id: F4LQ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

906968:TREBR RS11620
gene id: 906968:TREBR_RS11620
uniprot id: F4LL85
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

906968:TREBR RS07560
gene id: 906968:TREBR_RS07560
uniprot id: F4LNR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

906968:TREBR RS05795
gene id: 906968:TREBR_RS05795
uniprot id: F4LIJ9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

906968:TREBR RS01680
gene id: 906968:TREBR_RS01680
uniprot id: F4LN01
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS03845
gene id: 906968:TREBR_RS03845
uniprot id: F4LIF3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS03140
gene id: 906968:TREBR_RS03140
uniprot id: F4LPW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

906968:TREBR RS02575
gene id: 906968:TREBR_RS02575
uniprot id: F4LP71
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

906968:TREBR RS06460
gene id: 906968:TREBR_RS06460
uniprot id: F4LM11
names: Similarity
messages: Belongs to the BMP lipoprotein family.

906968:TREBR RS07580
gene id: 906968:TREBR_RS07580
uniprot id: F4LNR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

906968:TREBR RS11750
gene id: 906968:TREBR_RS11750
uniprot id: F4LLP3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

906968:TREBR RS11900
gene id: 906968:TREBR_RS11900
uniprot id: F4LLS3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

906968:TREBR RS04455
gene id: 906968:TREBR_RS04455
uniprot id: F4LJ54
names: Similarity
messages: Belongs to the CTP synthase family.

906968:TREBR RS11175
gene id: 906968:TREBR_RS11175
uniprot id: F4LKM3
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS03735
gene id: 906968:TREBR_RS03735
uniprot id: F4LID3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

906968:TREBR RS10405
gene id: 906968:TREBR_RS10405
uniprot id: F4LJQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS04600
gene id: 906968:TREBR_RS04600
uniprot id: F4LJ82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

906968:TREBR RS03005
gene id: 906968:TREBR_RS03005
uniprot id: F4LPT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

906968:TREBR RS02415
gene id: 906968:TREBR_RS02415
uniprot id: F4LP46
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

906968:TREBR RS11360
gene id: 906968:TREBR_RS11360
uniprot id: F4LL39
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

906968:TREBR RS09800
gene id: 906968:TREBR_RS09800
uniprot id: F4LJ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

906968:TREBR RS11000
gene id: 906968:TREBR_RS11000
uniprot id: F4LKJ0
names: Subcellular Location Annotation
messages: Cytoplasm

906968:TREBR RS04525
gene id: 906968:TREBR_RS04525
uniprot id: F4LJ67
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

906968:TREBR RS02505
gene id: 906968:TREBR_RS02505
uniprot id: F4LP59
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

906968:TREBR RS07950
gene id: 906968:TREBR_RS07950
uniprot id: F4LPA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

906968:TREBR RS01995
gene id: 906968:TREBR_RS01995
uniprot id: F4LNJ1
names: Similarity
messages: Belongs to the glutamine synthetase family.

906968:TREBR RS01855
gene id: 906968:TREBR_RS01855
uniprot id: F4LN32
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

906968:TREBR RS09580
gene id: 906968:TREBR_RS09580
uniprot id: F4LIW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

906968:TREBR RS05565
gene id: 906968:TREBR_RS05565
uniprot id: F4LKE4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

906968:TREBR RS00830
gene id: 906968:TREBR_RS00830
uniprot id: F4LLE5
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

906968:TREBR RS00470
gene id: 906968:TREBR_RS00470
uniprot id: F4LKU1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS08265
gene id: 906968:TREBR_RS08265
uniprot id: F4LPN2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

906968:TREBR RS00960
gene id: 906968:TREBR_RS00960
uniprot id: F4LLV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

906968:TREBR RS06310
gene id: 906968:TREBR_RS06310
uniprot id: F4LLJ6
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS00935
gene id: 906968:TREBR_RS00935
uniprot id: F4LLV1
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

906968:TREBR RS04995
gene id: 906968:TREBR_RS04995
uniprot id: F4LJL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

906968:TREBR RS02330
gene id: 906968:TREBR_RS02330
uniprot id: F4LP30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

906968:TREBR RS12215
gene id: 906968:TREBR_RS12215
uniprot id: F4LMA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

906968:TREBR RS03430
gene id: 906968:TREBR_RS03430
uniprot id: F4LQ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

906968:TREBR RS09100
gene id: 906968:TREBR_RS09100
uniprot id: F4LQH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

906968:TREBR RS06350
gene id: 906968:TREBR_RS06350
uniprot id: F4LLK3
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS05590
gene id: 906968:TREBR_RS05590
uniprot id: F4LKE9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

906968:TREBR RS10565
gene id: 906968:TREBR_RS10565
uniprot id: F4LJT4
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS07335
gene id: 906968:TREBR_RS07335
uniprot id: F4LN89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

906968:TREBR RS00590
gene id: 906968:TREBR_RS00590
uniprot id: F4LL98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS11115
gene id: 906968:TREBR_RS11115
uniprot id: F4LKL2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

906968:TREBR RS01605
gene id: 906968:TREBR_RS01605
uniprot id: F4LMY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS12550
gene id: 906968:TREBR_RS12550
uniprot id: F4LMV2
names: Similarity
messages: Belongs to the ArsC family.

906968:TREBR RS03300
gene id: 906968:TREBR_RS03300
uniprot id: F4LQ68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

906968:TREBR RS07360
gene id: 906968:TREBR_RS07360
uniprot id: F4LN93
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS10835
gene id: 906968:TREBR_RS10835
uniprot id: F4LK55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

906968:TREBR RS06560
gene id: 906968:TREBR_RS06560
uniprot id: F4LM26
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

906968:TREBR RS11755
gene id: 906968:TREBR_RS11755
uniprot id: F4LLP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

906968:TREBR RS01160
gene id: 906968:TREBR_RS01160
uniprot id: F4LLZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

906968:TREBR RS09730
gene id: 906968:TREBR_RS09730
uniprot id: F4LIZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

906968:TREBR RS12175
gene id: 906968:TREBR_RS12175
uniprot id: F4LMA2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

906968:TREBR RS03495
gene id: 906968:TREBR_RS03495
uniprot id: F4LQA6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

906968:TREBR RS10670
gene id: 906968:TREBR_RS10670
uniprot id: F4LK22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

906968:TREBR RS11775
gene id: 906968:TREBR_RS11775
uniprot id: F4LLP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

906968:TREBR RS10970
gene id: 906968:TREBR_RS10970
uniprot id: F4LKI4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

906968:TREBR RS05115
gene id: 906968:TREBR_RS05115
uniprot id: F4LJV6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

906968:TREBR RS10510
gene id: 906968:TREBR_RS10510
uniprot id: F4LJS3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS07160
gene id: 906968:TREBR_RS07160
uniprot id: F4LN54
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

906968:TREBR RS05810
gene id: 906968:TREBR_RS05810
uniprot id: F4LKW6
names: Similarity
messages: Belongs to the hexokinase family.

906968:TREBR RS07725
gene id: 906968:TREBR_RS07725
uniprot id: F4LNT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

906968:TREBR RS12280
gene id: 906968:TREBR_RS12280
uniprot id: F4LMC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

906968:TREBR RS13390
gene id: 906968:TREBR_RS13390
uniprot id: F4LMY9
names: Similarity
messages: Belongs to the peptidase C40 family.

906968:TREBR RS10580
gene id: 906968:TREBR_RS10580
uniprot id: F4LK05
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS01600
gene id: 906968:TREBR_RS01600
uniprot id: F4LMY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS08630
gene id: 906968:TREBR_RS08630
uniprot id: F4LQ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS00670
gene id: 906968:TREBR_RS00670
uniprot id: F4LLB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

906968:TREBR RS00680
gene id: 906968:TREBR_RS00680
uniprot id: F4LLB6
names: Similarity
messages: Belongs to the UPF0597 family.

906968:TREBR RS06710
gene id: 906968:TREBR_RS06710
uniprot id: F4LM56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

906968:TREBR RS09925
gene id: 906968:TREBR_RS09925
uniprot id: F4LJ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS11970
gene id: 906968:TREBR_RS11970
uniprot id: F4LLT4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

906968:TREBR RS10855
gene id: 906968:TREBR_RS10855
uniprot id: F4LK59
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS08695
gene id: 906968:TREBR_RS08695
uniprot id: F4LQ34
names: Similarity
messages: Belongs to the aspartokinase family.

906968:TREBR RS12305
gene id: 906968:TREBR_RS12305
uniprot id: F4LMC7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

906968:TREBR RS04800
gene id: 906968:TREBR_RS04800
uniprot id: F4LJI0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

906968:TREBR RS04780
gene id: 906968:TREBR_RS04780
uniprot id: F4LJH6
names: Similarity
messages: Belongs to the UPF0178 family.

906968:TREBR RS03235
gene id: 906968:TREBR_RS03235
uniprot id: F4LPY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

906968:TREBR RS08775
gene id: 906968:TREBR_RS08775
uniprot id: F4LQ50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

906968:TREBR RS06040
gene id: 906968:TREBR_RS06040
uniprot id: F4LL10
names: Subcellular Location Annotation
messages: Cytoplasm

906968:TREBR RS06280
gene id: 906968:TREBR_RS06280
uniprot id: F4LLJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

906968:TREBR RS11480
gene id: 906968:TREBR_RS11480
uniprot id: F4LL59
names: Cofactor
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

906968:TREBR RS06665
gene id: 906968:TREBR_RS06665
uniprot id: F4LM47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

906968:TREBR RS06020
gene id: 906968:TREBR_RS06020
uniprot id: F4LL06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

906968:TREBR RS02700
gene id: 906968:TREBR_RS02700
uniprot id: F4LPG1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

906968:TREBR RS05260
gene id: 906968:TREBR_RS05260
uniprot id: F4LJY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

906968:TREBR RS10385
gene id: 906968:TREBR_RS10385
uniprot id: F4LJP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS05830
gene id: 906968:TREBR_RS05830
uniprot id: F4LKX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Role in flagellar biosynthesis.

906968:TREBR RS04870
gene id: 906968:TREBR_RS04870
uniprot id: F4LJJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

906968:TREBR RS06600
gene id: 906968:TREBR_RS06600
uniprot id: F4LM34
names: Similarity
messages: Belongs to the DEAD box helicase family.

906968:TREBR RS03160
gene id: 906968:TREBR_RS03160
uniprot id: F4LPW9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

906968:TREBR RS07715
gene id: 906968:TREBR_RS07715
uniprot id: F4LNT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

906968:TREBR RS06025
gene id: 906968:TREBR_RS06025
uniprot id: F4LL07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

906968:TREBR RS07730
gene id: 906968:TREBR_RS07730
uniprot id: F4LNT9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

906968:TREBR RS10685
gene id: 906968:TREBR_RS10685
uniprot id: F4LK25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

906968:TREBR RS11910
gene id: 906968:TREBR_RS11910
uniprot id: F4LLS4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

906968:TREBR RS11105
gene id: 906968:TREBR_RS11105
uniprot id: F4LKL0
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS05175
gene id: 906968:TREBR_RS05175
uniprot id: F4LJW7
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS01845
gene id: 906968:TREBR_RS01845
uniprot id: F4LN30
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

906968:TREBR RS03715
gene id: 906968:TREBR_RS03715
uniprot id: F4LID0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

906968:TREBR RS09745
gene id: 906968:TREBR_RS09745
uniprot id: F4LIZ5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

906968:TREBR RS03440
gene id: 906968:TREBR_RS03440
uniprot id: F4LQ96
names: Similarity
messages: Belongs to the glutamate synthase family.

906968:TREBR RS09930
gene id: 906968:TREBR_RS09930
uniprot id: F4LJ96
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

906968:TREBR RS10080
gene id: 906968:TREBR_RS10080
uniprot id: F4LJC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

906968:TREBR RS09150
gene id: 906968:TREBR_RS09150
uniprot id: F4LQI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

906968:TREBR RS05505
gene id: 906968:TREBR_RS05505
uniprot id: F4LKD2
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

906968:TREBR RS09815
gene id: 906968:TREBR_RS09815
uniprot id: F4LJ09
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

906968:TREBR RS09135
gene id: 906968:TREBR_RS09135
uniprot id: F4LQI4
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

906968:TREBR RS10705
gene id: 906968:TREBR_RS10705
uniprot id: F4LK29
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

906968:TREBR RS03840
gene id: 906968:TREBR_RS03840
uniprot id: F4LIF2
names: Similarity
messages: Belongs to the peptidase S11 family.

906968:TREBR RS08345
gene id: 906968:TREBR_RS08345
uniprot id: F4LPP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

906968:TREBR RS07860
gene id: 906968:TREBR_RS07860
uniprot id: F4LP89
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

906968:TREBR RS06940
gene id: 906968:TREBR_RS06940
uniprot id: F4LMN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

906968:TREBR RS03590
gene id: 906968:TREBR_RS03590
uniprot id: F4LQC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

906968:TREBR RS12450
gene id: 906968:TREBR_RS12450
uniprot id: F4LMT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

906968:TREBR RS04925
gene id: 906968:TREBR_RS04925
uniprot id: F4LJK5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane

906968:TREBR RS04025
gene id: 906968:TREBR_RS04025
uniprot id: F4LIQ2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

906968:TREBR RS08625
gene id: 906968:TREBR_RS08625
uniprot id: F4LQ21
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

906968:TREBR RS03825
gene id: 906968:TREBR_RS03825
uniprot id: F4LIE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

906968:TREBR RS00585
gene id: 906968:TREBR_RS00585
uniprot id: F4LL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS04705
gene id: 906968:TREBR_RS04705
uniprot id: F4LJG5
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS03415
gene id: 906968:TREBR_RS03415
uniprot id: F4LQ91
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

906968:TREBR RS09535
gene id: 906968:TREBR_RS09535
uniprot id: F4LIN9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

906968:TREBR RS11220
gene id: 906968:TREBR_RS11220
uniprot id: F4LKN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

906968:TREBR RS04575
gene id: 906968:TREBR_RS04575
uniprot id: F4LJ77
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

906968:TREBR RS11780
gene id: 906968:TREBR_RS11780
uniprot id: F4LLQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

906968:TREBR RS06415
gene id: 906968:TREBR_RS06415
uniprot id: F4LLL7
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS14650
gene id: 906968:TREBR_RS14650
uniprot id: F4LM36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

906968:TREBR RS01395
gene id: 906968:TREBR_RS01395
uniprot id: F4LMH0
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS03270
gene id: 906968:TREBR_RS03270
uniprot id: F4LPZ1
names: Similarity
messages: Belongs to the peptidase S49 family.

906968:TREBR RS05515
gene id: 906968:TREBR_RS05515
uniprot id: F4LKD4
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS03405
gene id: 906968:TREBR_RS03405
uniprot id: F4LQ89
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

906968:TREBR RS08015
gene id: 906968:TREBR_RS08015
uniprot id: F4LPB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS02800
gene id: 906968:TREBR_RS02800
uniprot id: F4LPI1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

906968:TREBR RS03125
gene id: 906968:TREBR_RS03125
uniprot id: F4LPW2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

906968:TREBR RS10530
gene id: 906968:TREBR_RS10530
uniprot id: F4LJS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

906968:TREBR RS12695
gene id: 906968:TREBR_RS12695
uniprot id: F4LNB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

906968:TREBR RS10645
gene id: 906968:TREBR_RS10645
uniprot id: F4LK18
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS04125
gene id: 906968:TREBR_RS04125
uniprot id: F4LIS2
names: Similarity
messages: Belongs to the TPP enzyme family.

906968:TREBR RS09905
gene id: 906968:TREBR_RS09905
uniprot id: F4LJ27
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

906968:TREBR RS04795
gene id: 906968:TREBR_RS04795
uniprot id: F4LJH9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

906968:TREBR RS08280
gene id: 906968:TREBR_RS08280
uniprot id: F4LPN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

906968:TREBR RS04430
gene id: 906968:TREBR_RS04430
uniprot id: F4LJ49
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

906968:TREBR RS03670
gene id: 906968:TREBR_RS03670
uniprot id: F4LIC1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

906968:TREBR RS01645
gene id: 906968:TREBR_RS01645
uniprot id: F4LMZ4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

906968:TREBR RS05520
gene id: 906968:TREBR_RS05520
uniprot id: F4LKD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

906968:TREBR RS03650
gene id: 906968:TREBR_RS03650
uniprot id: F4LIB7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

906968:TREBR RS11815
gene id: 906968:TREBR_RS11815
uniprot id: F4LLQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

906968:TREBR RS10180
gene id: 906968:TREBR_RS10180
uniprot id: F4LJE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

906968:TREBR RS13010
gene id: 906968:TREBR_RS13010
uniprot id: F4LNV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS13410
gene id: 906968:TREBR_RS13410
uniprot id: F4LN11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

906968:TREBR RS13400
gene id: 906968:TREBR_RS13400
uniprot id: F4LMZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

906968:TREBR RS13175
gene id: 906968:TREBR_RS13175
uniprot id: F4LNY7
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

906968:TREBR RS11765
gene id: 906968:TREBR_RS11765
uniprot id: F4LLP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

906968:TREBR RS04890
gene id: 906968:TREBR_RS04890
uniprot id: F4LJJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

906968:TREBR RS11705
gene id: 906968:TREBR_RS11705
uniprot id: F4LLN2
names: Similarity
messages: Belongs to the leucine-binding protein family.

906968:TREBR RS10375
gene id: 906968:TREBR_RS10375
uniprot id: F4LJP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

906968:TREBR RS04005
gene id: 906968:TREBR_RS04005
uniprot id: F4LIP8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

906968:TREBR RS12430
gene id: 906968:TREBR_RS12430
uniprot id: F4LMS8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

906968:TREBR RS08125
gene id: 906968:TREBR_RS08125
uniprot id: F4LPD9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

906968:TREBR RS00315
gene id: 906968:TREBR_RS00315
uniprot id: F4LKR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

906968:TREBR RS09605
gene id: 906968:TREBR_RS09605
uniprot id: F4LIW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

906968:TREBR RS07945
gene id: 906968:TREBR_RS07945
uniprot id: F4LPA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

906968:TREBR RS04475
gene id: 906968:TREBR_RS04475
uniprot id: F4LJ58
names: Similarity
messages: Belongs to the hemerythrin family.

906968:TREBR RS12015
gene id: 906968:TREBR_RS12015
uniprot id: F4LM70
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

906968:TREBR RS02355
gene id: 906968:TREBR_RS02355
uniprot id: F4LP35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS13805
gene id: 906968:TREBR_RS13805
uniprot id: F4LJE0
names: Similarity
messages: Belongs to the RibF family.

906968:TREBR RS04695
gene id: 906968:TREBR_RS04695
uniprot id: F4LJG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

906968:TREBR RS01240
gene id: 906968:TREBR_RS01240
uniprot id: F4LME0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS06425
gene id: 906968:TREBR_RS06425
uniprot id: F4LM04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

906968:TREBR RS07405
gene id: 906968:TREBR_RS07405
uniprot id: F4LNA2
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

906968:TREBR RS09785
gene id: 906968:TREBR_RS09785
uniprot id: F4LJ03
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS04960
gene id: 906968:TREBR_RS04960
uniprot id: F4LJL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

906968:TREBR RS11855
gene id: 906968:TREBR_RS11855
uniprot id: F4LLR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

906968:TREBR RS02805
gene id: 906968:TREBR_RS02805
uniprot id: F4LPI2
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS05380
gene id: 906968:TREBR_RS05380
uniprot id: F4LK02
names: Similarity
messages: Belongs to the hemerythrin family.

906968:TREBR RS05695
gene id: 906968:TREBR_RS05695
uniprot id: F4LKG9
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

906968:TREBR RS05620
gene id: 906968:TREBR_RS05620
uniprot id: F4LKF5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

906968:TREBR RS07285
gene id: 906968:TREBR_RS07285
uniprot id: F4LN79
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

906968:TREBR RS13635
gene id: 906968:TREBR_RS13635
uniprot id: F4LM63
names: Similarity
messages: Belongs to the bacterial secretin family.

906968:TREBR RS12225
gene id: 906968:TREBR_RS12225
uniprot id: F4LMB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

906968:TREBR RS11225
gene id: 906968:TREBR_RS11225
uniprot id: F4LKN3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

906968:TREBR RS05530
gene id: 906968:TREBR_RS05530
uniprot id: F4LKD7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

906968:TREBR RS11760
gene id: 906968:TREBR_RS11760
uniprot id: F4LLP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

906968:TREBR RS02940
gene id: 906968:TREBR_RS02940
uniprot id: F4LPS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS00610
gene id: 906968:TREBR_RS00610
uniprot id: F4LLA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

906968:TREBR RS00405
gene id: 906968:TREBR_RS00405
uniprot id: F4LKS8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

906968:TREBR RS12685
gene id: 906968:TREBR_RS12685
uniprot id: F4LNB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

906968:TREBR RS00180
gene id: 906968:TREBR_RS00180
uniprot id: F4LKA6
names: Similarity
messages: Belongs to the group II decarboxylase family.

906968:TREBR RS06475
gene id: 906968:TREBR_RS06475
uniprot id: F4LM14
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS09005
gene id: 906968:TREBR_RS09005
uniprot id: F4LQF9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

906968:TREBR RS00085
gene id: 906968:TREBR_RS00085
uniprot id: F4LK88
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

906968:TREBR RS05730
gene id: 906968:TREBR_RS05730
uniprot id: F4LKH6
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

906968:TREBR RS10740
gene id: 906968:TREBR_RS10740
uniprot id: F4LK36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

906968:TREBR RS08550
gene id: 906968:TREBR_RS08550
uniprot id: F4LQ06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

906968:TREBR RS05840
gene id: 906968:TREBR_RS05840
uniprot id: F4LKX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

906968:TREBR RS08180
gene id: 906968:TREBR_RS08180
uniprot id: F4LPL6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

906968:TREBR RS10175
gene id: 906968:TREBR_RS10175
uniprot id: F4LJE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

906968:TREBR RS05955
gene id: 906968:TREBR_RS05955
uniprot id: F4LKZ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

906968:TREBR RS13125
gene id: 906968:TREBR_RS13125
uniprot id: F4LNX7
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

906968:TREBR RS04435
gene id: 906968:TREBR_RS04435
uniprot id: F4LJ50
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS07125
gene id: 906968:TREBR_RS07125
uniprot id: F4LN47
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

906968:TREBR RS08250
gene id: 906968:TREBR_RS08250
uniprot id: F4LPM9
names: Similarity
messages: Belongs to the MotB family.

906968:TREBR RS05900
gene id: 906968:TREBR_RS05900
uniprot id: F4LKY3
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS03180
gene id: 906968:TREBR_RS03180
uniprot id: F4LPX3
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

906968:TREBR RS07060
gene id: 906968:TREBR_RS07060
uniprot id: F4LMQ2
names: Similarity
messages: Belongs to the FemABX family.

906968:TREBR RS08595
gene id: 906968:TREBR_RS08595
uniprot id: F4LQ15
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

906968:TREBR RS11945
gene id: 906968:TREBR_RS11945
uniprot id: F4LLT1
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

906968:TREBR RS03540
gene id: 906968:TREBR_RS03540
uniprot id: F4LQB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

906968:TREBR RS04690
gene id: 906968:TREBR_RS04690
uniprot id: F4LJG2
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

906968:TREBR RS00870
gene id: 906968:TREBR_RS00870
uniprot id: F4LLT9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

906968:TREBR RS05580
gene id: 906968:TREBR_RS05580
uniprot id: F4LKE7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

906968:TREBR RS04390
gene id: 906968:TREBR_RS04390
uniprot id: F4LJ40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

906968:TREBR RS05255
gene id: 906968:TREBR_RS05255
uniprot id: F4LJY2
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

906968:TREBR RS07065
gene id: 906968:TREBR_RS07065
uniprot id: F4LMQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

906968:TREBR RS13365
gene id: 906968:TREBR_RS13365
uniprot id: F4LLV0
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

906968:TREBR RS10850
gene id: 906968:TREBR_RS10850
uniprot id: F4LK58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

906968:TREBR RS04895
gene id: 906968:TREBR_RS04895
uniprot id: F4LJJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

906968:TREBR RS02500
gene id: 906968:TREBR_RS02500
uniprot id: F4LP58
names: Function
names: Similarity
messages: Belongs to the PyrI family.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

906968:TREBR RS04480
gene id: 906968:TREBR_RS04480
uniprot id: F4LJ59
names: Similarity
messages: Belongs to the hemerythrin family.

906968:TREBR RS11770
gene id: 906968:TREBR_RS11770
uniprot id: F4LLP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

906968:TREBR RS07290
gene id: 906968:TREBR_RS07290
uniprot id: F4LN80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

906968:TREBR RS00815
gene id: 906968:TREBR_RS00815
uniprot id: F4LLE2
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

906968:TREBR RS00545
gene id: 906968:TREBR_RS00545
uniprot id: F4LL89
names: Similarity
messages: Belongs to the citrate synthase family.

906968:TREBR RS05425
gene id: 906968:TREBR_RS05425
uniprot id: F4LKB6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

906968:TREBR RS06960
gene id: 906968:TREBR_RS06960
uniprot id: F4LMN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

906968:TREBR RS10635
gene id: 906968:TREBR_RS10635
uniprot id: F4LK16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

906968:TREBR RS11790
gene id: 906968:TREBR_RS11790
uniprot id: F4LLQ2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

906968:TREBR RS04010
gene id: 906968:TREBR_RS04010
uniprot id: F4LIP9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

906968:TREBR RS11700
gene id: 906968:TREBR_RS11700
uniprot id: F4LLN1
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS10210
gene id: 906968:TREBR_RS10210
uniprot id: F4LIJ9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

906968:TREBR RS11965
gene id: 906968:TREBR_RS11965
uniprot id: F4LLT3
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS03550
gene id: 906968:TREBR_RS03550
uniprot id: F4LQB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

906968:TREBR RS04225
gene id: 906968:TREBR_RS04225
uniprot id: F4LIU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

906968:TREBR RS02740
gene id: 906968:TREBR_RS02740
uniprot id: F4LPG9
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS08580
gene id: 906968:TREBR_RS08580
uniprot id: F4LQ12
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

906968:TREBR RS01860
gene id: 906968:TREBR_RS01860
uniprot id: F4LN33
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

906968:TREBR RS04220
gene id: 906968:TREBR_RS04220
uniprot id: F4LIU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

906968:TREBR RS00645
gene id: 906968:TREBR_RS00645
uniprot id: F4LLA9
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS09185
gene id: 906968:TREBR_RS09185
uniprot id: F4LQJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

906968:TREBR RS06375
gene id: 906968:TREBR_RS06375
uniprot id: F4LLK8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

906968:TREBR RS13060
gene id: 906968:TREBR_RS13060
uniprot id: F4LNW7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

906968:TREBR RS10955
gene id: 906968:TREBR_RS10955
uniprot id: F4LKI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

906968:TREBR RS06440
gene id: 906968:TREBR_RS06440
uniprot id: F4LM07
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

906968:TREBR RS02600
gene id: 906968:TREBR_RS02600
uniprot id: F4LP76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

906968:TREBR RS02495
gene id: 906968:TREBR_RS02495
uniprot id: F4LP57
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

906968:TREBR RS08860
gene id: 906968:TREBR_RS08860
uniprot id: F4LQD5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

906968:TREBR RS06195
gene id: 906968:TREBR_RS06195
uniprot id: F4LLH4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS07295
gene id: 906968:TREBR_RS07295
uniprot id: F4LN81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

906968:TREBR RS07620
gene id: 906968:TREBR_RS07620
uniprot id: F4LNS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

906968:TREBR RS14225
gene id: 906968:TREBR_RS14225
uniprot id: F4LNK0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

906968:TREBR RS05615
gene id: 906968:TREBR_RS05615
uniprot id: F4LKF4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

906968:TREBR RS06870
gene id: 906968:TREBR_RS06870
uniprot id: F4LML8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

906968:TREBR RS06705
gene id: 906968:TREBR_RS06705
uniprot id: F4LM55
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

906968:TREBR RS12805
gene id: 906968:TREBR_RS12805
uniprot id: F4LND4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

906968:TREBR RS12965
gene id: 906968:TREBR_RS12965
uniprot id: F4LNG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS05005
gene id: 906968:TREBR_RS05005
uniprot id: F4LJT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

906968:TREBR RS02680
gene id: 906968:TREBR_RS02680
uniprot id: F4LPF7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

906968:TREBR RS04190
gene id: 906968:TREBR_RS04190
uniprot id: F4LIT5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS12775
gene id: 906968:TREBR_RS12775
uniprot id: F4LNC8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

906968:TREBR RS01390
gene id: 906968:TREBR_RS01390
uniprot id: F4LMG9
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

906968:TREBR RS12525
gene id: 906968:TREBR_RS12525
uniprot id: F4LMU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

906968:TREBR RS05575
gene id: 906968:TREBR_RS05575
uniprot id: F4LKE6
names: Similarity
messages: Belongs to the RecJ family.

906968:TREBR RS10490
gene id: 906968:TREBR_RS10490
uniprot id: F4LJR9
names: Similarity
messages: Belongs to the HdrA family.

906968:TREBR RS08675
gene id: 906968:TREBR_RS08675
uniprot id: F4LQ30
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

906968:TREBR RS09400
gene id: 906968:TREBR_RS09400
uniprot id: F4LIL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

906968:TREBR RS05110
gene id: 906968:TREBR_RS05110
uniprot id: F4LJV5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

906968:TREBR RS11675
gene id: 906968:TREBR_RS11675
uniprot id: F4LLM6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

906968:TREBR RS06145
gene id: 906968:TREBR_RS06145
uniprot id: F4LLG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

906968:TREBR RS08780
gene id: 906968:TREBR_RS08780
uniprot id: F4LQ51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

906968:TREBR RS07050
gene id: 906968:TREBR_RS07050
uniprot id: F4LMQ0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

906968:TREBR RS12030
gene id: 906968:TREBR_RS12030
uniprot id: F4LM73
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS07640
gene id: 906968:TREBR_RS07640
uniprot id: F4LNS4
names: Similarity
messages: Belongs to the TrpR family.

906968:TREBR RS09170
gene id: 906968:TREBR_RS09170
uniprot id: F4LQJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

906968:TREBR RS03810
gene id: 906968:TREBR_RS03810
uniprot id: F4LIE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

906968:TREBR RS00640
gene id: 906968:TREBR_RS00640
uniprot id: F4LLA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

906968:TREBR RS02135
gene id: 906968:TREBR_RS02135
uniprot id: F4LNL5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

906968:TREBR RS07310
gene id: 906968:TREBR_RS07310
uniprot id: F4LN84
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS00030
gene id: 906968:TREBR_RS00030
uniprot id: F4LK78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

906968:TREBR RS12535
gene id: 906968:TREBR_RS12535
uniprot id: F4LMU9
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

906968:TREBR RS04035
gene id: 906968:TREBR_RS04035
uniprot id: F4LIQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

906968:TREBR RS09425
gene id: 906968:TREBR_RS09425
uniprot id: F4LIL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

906968:TREBR RS00695
gene id: 906968:TREBR_RS00695
uniprot id: F4LLB9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS07465
gene id: 906968:TREBR_RS07465
uniprot id: F4LNP3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

906968:TREBR RS11560
gene id: 906968:TREBR_RS11560
uniprot id: F4LL73
names: Similarity
messages: Belongs to the disproportionating enzyme family.

906968:TREBR RS09795
gene id: 906968:TREBR_RS09795
uniprot id: F4LJ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

906968:TREBR RS08685
gene id: 906968:TREBR_RS08685
uniprot id: F4LQ32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

906968:TREBR RS07985
gene id: 906968:TREBR_RS07985
uniprot id: F4LPB3
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

906968:TREBR RS09525
gene id: 906968:TREBR_RS09525
uniprot id: F4LIN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

906968:TREBR RS05150
gene id: 906968:TREBR_RS05150
uniprot id: F4LIJ9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

906968:TREBR RS04015
gene id: 906968:TREBR_RS04015
uniprot id: F4LIQ0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

906968:TREBR RS04985
gene id: 906968:TREBR_RS04985
uniprot id: F4LJL7
names: Similarity
messages: Belongs to the DtxR/MntR family.

906968:TREBR RS08545
gene id: 906968:TREBR_RS08545
uniprot id: F4LQ05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

906968:TREBR RS11880
gene id: 906968:TREBR_RS11880
uniprot id: F4LLS0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

906968:TREBR RS01875
gene id: 906968:TREBR_RS01875
uniprot id: F4LN36
names: Similarity
messages: Belongs to the ParB family.

906968:TREBR RS08245
gene id: 906968:TREBR_RS08245
uniprot id: F4LPM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

906968:TREBR RS09765
gene id: 906968:TREBR_RS09765
uniprot id: F4LIZ9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

906968:TREBR RS11725
gene id: 906968:TREBR_RS11725
uniprot id: F4LLN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

906968:TREBR RS06450
gene id: 906968:TREBR_RS06450
uniprot id: F4LM09
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

906968:TREBR RS06365
gene id: 906968:TREBR_RS06365
uniprot id: F4LLK6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

906968:TREBR RS11885
gene id: 906968:TREBR_RS11885
uniprot id: F4LLS1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

906968:TREBR RS06965
gene id: 906968:TREBR_RS06965
uniprot id: F4LMN5
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

906968:TREBR RS11505
gene id: 906968:TREBR_RS11505
uniprot id: F4LL63
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS11655
gene id: 906968:TREBR_RS11655
uniprot id: F4LLM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

906968:TREBR RS07875
gene id: 906968:TREBR_RS07875
uniprot id: F4LP92
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

906968:TREBR RS04945
gene id: 906968:TREBR_RS04945
uniprot id: F4LJK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

906968:TREBR RS00865
gene id: 906968:TREBR_RS00865
uniprot id: F4LLF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

906968:TREBR RS05895
gene id: 906968:TREBR_RS05895
uniprot id: F4LKY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS03460
gene id: 906968:TREBR_RS03460
uniprot id: F4LQA0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

906968:TREBR RS02605
gene id: 906968:TREBR_RS02605
uniprot id: F4LPE2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

906968:TREBR RS00340
gene id: 906968:TREBR_RS00340
uniprot id: F4LKR6
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS11805
gene id: 906968:TREBR_RS11805
uniprot id: F4LLQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

906968:TREBR RS01440
gene id: 906968:TREBR_RS01440
uniprot id: F4LMH9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

906968:TREBR RS09880
gene id: 906968:TREBR_RS09880
uniprot id: F4LJ22
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

906968:TREBR RS08145
gene id: 906968:TREBR_RS08145
uniprot id: F4LPK9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

906968:TREBR RS04605
gene id: 906968:TREBR_RS04605
uniprot id: F4LJ83
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

906968:TREBR RS02785
gene id: 906968:TREBR_RS02785
uniprot id: F4LPH8
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

906968:TREBR RS07260
gene id: 906968:TREBR_RS07260
uniprot id: F4LN75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

906968:TREBR RS07775
gene id: 906968:TREBR_RS07775
uniprot id: F4LNU9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

906968:TREBR RS13525
gene id: 906968:TREBR_RS13525
uniprot id: F4LJ75
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

906968:TREBR RS04635
gene id: 906968:TREBR_RS04635
uniprot id: F4LJ89
names: Similarity
messages: Belongs to the UPF0102 family.

906968:TREBR RS12700
gene id: 906968:TREBR_RS12700
uniprot id: F4LNB4
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

906968:TREBR RS05990
gene id: 906968:TREBR_RS05990
uniprot id: F4LL00
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

906968:TREBR RS11860
gene id: 906968:TREBR_RS11860
uniprot id: F4LLR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

906968:TREBR RS00335
gene id: 906968:TREBR_RS00335
uniprot id: F4LKR5
names: Subcellular Location Annotation
messages: Membrane

906968:TREBR RS13905
gene id: 906968:TREBR_RS13905
uniprot id: F4LLS5
names: Similarity
messages: Belongs to the FemABX family.

906968:TREBR RS11740
gene id: 906968:TREBR_RS11740
uniprot id: F4LLP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

906968:TREBR RS10100
gene id: 906968:TREBR_RS10100
uniprot id: F4LJC8
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

906968:TREBR RS08745
gene id: 906968:TREBR_RS08745
uniprot id: F4LQ44
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

906968:TREBR RS12325
gene id: 906968:TREBR_RS12325
uniprot id: F4LMD1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

906968:TREBR RS07900
gene id: 906968:TREBR_RS07900
uniprot id: F4LP97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

906968:TREBR RS08560
gene id: 906968:TREBR_RS08560
uniprot id: F4LQ08
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

906968:TREBR RS00800
gene id: 906968:TREBR_RS00800
uniprot id: F4LLD9
names: Subcellular Location Annotation
messages: Membrane