89673:YPEL2
gene id: 89673:YPEL2
uniprot id: A0A6J2M729
names: Similarity
messages: Belongs to the yippee family.

89673:SLC35B3
gene id: 89673:SLC35B3
uniprot id: A0A6J2LN01
uniprot id: A0A6J2LS28
uniprot id: A0A7E6DTB3
uniprot id: A0A7E6DU31
uniprot id: A0A7E6DUI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

89673:FLNC
gene id: 89673:FLNC
uniprot id: A0A6J2MSQ6
names: Similarity
messages: Belongs to the filamin family.

89673:DMGDH
gene id: 89673:DMGDH
uniprot id: A0A6J2MQW6
names: Similarity
messages: Belongs to the GcvT family.

89673:STRN4
gene id: 89673:STRN4
uniprot id: A0A6J2N4U7
uniprot id: A0A7E6CQG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

89673:KIF4A
gene id: 89673:KIF4A
uniprot id: A0A6J2ME43
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:COPB1
gene id: 89673:COPB1
uniprot id: A0A6J2LZL2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Endoplasmic reticulum-Golgi intermediate compartment
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

89673:LOC114494843
gene id: 89673:LOC114494843
uniprot id: A0A7E6DHE0
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

89673:LOC114491310
gene id: 89673:LOC114491310
uniprot id: A0A7E6DQT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:ESYT3
gene id: 89673:ESYT3
uniprot id: A0A6J2M2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:GLOD4
gene id: 89673:GLOD4
uniprot id: A0A6J2MAU9
names: Similarity
messages: Belongs to the glyoxalase I family.

89673:ANKLE2
gene id: 89673:ANKLE2
uniprot id: A0A6J2KXK6
uniprot id: A0A7E6CUD4
names: Similarity
messages: Belongs to the ANKLE2 family.

89673:PITPNM2
gene id: 89673:PITPNM2
uniprot id: A0A6J2MXN5
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

89673:TRAF2
gene id: 89673:TRAF2
uniprot id: A0A6J2MEW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

89673:LOC114499068
gene id: 89673:LOC114499068
uniprot id: A0A6J2LXX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PCCA
gene id: 89673:PCCA
uniprot id: A0A6J2MPI7
uniprot id: A0A6J2MW63
uniprot id: A0A7E6CK89
names: Subcellular Location Annotation
messages: Mitochondrion matrix

89673:ATP12A
gene id: 89673:ATP12A
uniprot id: A0A7E6D4Y8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:MYH10
gene id: 89673:MYH10
uniprot id: A0A7E6ECW9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:SATB2
gene id: 89673:SATB2
uniprot id: A0A6J2LCK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

89673:LOC114499061
gene id: 89673:LOC114499061
uniprot id: A0A6J2LYB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CLEC16A
gene id: 89673:CLEC16A
uniprot id: A0A6J2L825
uniprot id: A0A6J2L972
uniprot id: A0A6J2L989
uniprot id: A0A6J2LC65
uniprot id: A0A6J2LC83
uniprot id: A0A6J2LCA4
uniprot id: A0A6J2LDD9
uniprot id: A0A7E6DBQ3
uniprot id: A0A7E6DBY7
uniprot id: A0A7E6DCA8
uniprot id: A0A7E6DDJ8
names: Similarity
messages: Belongs to the CLEC16A/gop-1 family.

89673:ACADS
gene id: 89673:ACADS
uniprot id: A0A6J2N3I0
uniprot id: A0A7E6CUN1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

89673:TMX2
gene id: 89673:TMX2
uniprot id: A0A6J2LXG1
uniprot id: A0A7E6E2S3
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity. Indirectly regulates neuronal proliferation, migration, and organization in the developing brain.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

89673:NCAM1
gene id: 89673:NCAM1
uniprot id: A0A6J2LQW5
uniprot id: A0A6J2LW02
uniprot id: A0A6J2LW07
uniprot id: A0A6J2LWA8
uniprot id: A0A6J2LWB3
uniprot id: A0A6J2LWC0
uniprot id: A0A7E6DYZ8
uniprot id: A0A7E6DZ03
uniprot id: A0A7E6DZ18
uniprot id: A0A7E6DZ25
uniprot id: A0A7E6DZ31
uniprot id: A0A7E6DZG8
uniprot id: A0A7E6DZH4
uniprot id: A0A7E6DZY6
uniprot id: A0A7E6DZZ1
uniprot id: A0A7E6E0A0
uniprot id: A0A7E6E0A6
names: Function
messages: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

89673:LOC114503676
gene id: 89673:LOC114503676
uniprot id: A0A7E6E9B5
uniprot id: A0A7E6EAD1
uniprot id: A0A7E6EAY9
uniprot id: A0A7E6EBC3
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:RPS8
gene id: 89673:RPS8
uniprot id: A0A6J2LTI6
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs.

89673:UCMA
gene id: 89673:UCMA
uniprot id: A0A6J2L8M9
uniprot id: A0A7E6DP46
uniprot id: A0A7E6DP50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

89673:LOC114508082
gene id: 89673:LOC114508082
uniprot id: A0A6J2MV89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:B3GALT5
gene id: 89673:B3GALT5
uniprot id: A0A6J2L2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC114492839
gene id: 89673:LOC114492839
uniprot id: A0A6J2L8B5
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

89673:LOC114510112
gene id: 89673:LOC114510112
uniprot id: A0A6J2N3T4
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

89673:LYZL6
gene id: 89673:LYZL6
uniprot id: A0A6J2M4F0
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

89673:LOC114505639
gene id: 89673:LOC114505639
uniprot id: A0A7E6D0G5
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:LOC114488772
gene id: 89673:LOC114488772
uniprot id: A0A6J2KSI0
names: Similarity
messages: Belongs to the CD200R family.

89673:FOS
gene id: 89673:FOS
uniprot id: A0A6J2L9F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Fos subfamily.
messages: cytosol

89673:LOC114493803
gene id: 89673:LOC114493803
uniprot id: A0A6J2L9M5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.

89673:CYLD
gene id: 89673:CYLD
uniprot id: A0A6J2KQ60
uniprot id: A0A7E6CRG6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

89673:LOC114491805
gene id: 89673:LOC114491805
uniprot id: A0A6J2L718
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

89673:LOC114498697
gene id: 89673:LOC114498697
uniprot id: A0A7E6E486
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

89673:SRD5A1
gene id: 89673:SRD5A1
uniprot id: A0A6J2MG78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane
messages: Microsome membrane

89673:TBCE
gene id: 89673:TBCE
uniprot id: A0A6J2N543
uniprot id: A0A7E6CY76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

89673:SLC7A14
gene id: 89673:SLC7A14
uniprot id: A0A7E6CXY9
names: Subcellular Location Annotation
messages: Membrane

89673:C12H15orf40
gene id: 89673:C12H15orf40
uniprot id: A0A6J2KS38
names: Similarity
messages: Belongs to the UPF0235 family.

89673:VKORC1
gene id: 89673:VKORC1
uniprot id: A0A6J2MJ38
uniprot id: A0A6J2MN90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:ATP6AP1L
gene id: 89673:ATP6AP1L
uniprot id: A0A6J2L769
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

89673:MALSU1
gene id: 89673:MALSU1
uniprot id: A0A6J2MUI6
names: Similarity
messages: Belongs to the Iojap/RsfS family.

89673:PFN3
gene id: 89673:PFN3
uniprot id: A0A7E6CSL8
names: Similarity
messages: Belongs to the profilin family.

89673:LOC114497271
gene id: 89673:LOC114497271
uniprot id: A0A6J2LS63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

89673:GJC2
gene id: 89673:GJC2
uniprot id: A0A6J2NJL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:ARHGAP26
gene id: 89673:ARHGAP26
uniprot id: A0A6J2MSI9
uniprot id: A0A6J2MU68
uniprot id: A0A7E6CSF6
uniprot id: A0A7E6CSW7
uniprot id: A0A7E6CT49
names: Subcellular Location Annotation
messages: cytoskeleton
messages: focal adhesion

89673:RANBP6
gene id: 89673:RANBP6
uniprot id: A0A6J2LER6
uniprot id: A0A6J2LFX7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:ACE
gene id: 89673:ACE
uniprot id: A0A6J2M647
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

89673:RAB33B
gene id: 89673:RAB33B
uniprot id: A0A6J2MAJ4
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

89673:ST3GAL5
gene id: 89673:ST3GAL5
uniprot id: A0A6J2LYR0
uniprot id: A0A7E6DY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:LOC114505001
gene id: 89673:LOC114505001
uniprot id: A0A7E6CYR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:OLFML1
gene id: 89673:OLFML1
uniprot id: A0A6J2LSV0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114490730
gene id: 89673:LOC114490730
uniprot id: A0A6J2L4H7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:NIPAL2
gene id: 89673:NIPAL2
uniprot id: A0A6J2NBI4
uniprot id: A0A7E6E7C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

89673:IDUA
gene id: 89673:IDUA
uniprot id: A0A6J2L240
uniprot id: A0A7E6D3Z3
uniprot id: A0A7E6D645
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

89673:LOC114504039
gene id: 89673:LOC114504039
uniprot id: A0A6J2MGR8
uniprot id: A0A7E6EEL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

89673:ITIH5
gene id: 89673:ITIH5
uniprot id: A0A6J2L7J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

89673:SPCS2
gene id: 89673:SPCS2
uniprot id: A0A6J2LXZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:SERBP1
gene id: 89673:SERBP1
uniprot id: A0A6J2LIH4
uniprot id: A0A6J2LJM8
uniprot id: A0A6J2LM89
uniprot id: A0A6J2LMZ2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:FMC1
gene id: 89673:FMC1
uniprot id: A0A6J2MQT9
names: Similarity
messages: Belongs to the FMC1 family.

89673:HSD17B8
gene id: 89673:HSD17B8
uniprot id: A0A7E6DL17
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:LOC114507695
gene id: 89673:LOC114507695
uniprot id: A0A6J2MPL9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

89673:PTER
gene id: 89673:PTER
uniprot id: A0A6J2LE77
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:AFAP1L1
gene id: 89673:AFAP1L1
uniprot id: A0A6J2N3E2
uniprot id: A0A7E6CUK7
uniprot id: A0A7E6CV29
uniprot id: A0A7E6CVC8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

89673:TNFAIP1
gene id: 89673:TNFAIP1
uniprot id: A0A6J2MC02
names: Similarity
messages: Belongs to the BACURD family.

89673:LOC114499084
gene id: 89673:LOC114499084
uniprot id: A0A7E6E205
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DENND5B
gene id: 89673:DENND5B
uniprot id: A0A6J2N5A2
uniprot id: A0A6J2NBV6
uniprot id: A0A7E6D793
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GRIN2C
gene id: 89673:GRIN2C
uniprot id: A0A7E6EEH6
uniprot id: A0A7E6EG31
uniprot id: A0A7E6EG92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

89673:MMP28
gene id: 89673:MMP28
uniprot id: A0A6J2MB13
names: Similarity
messages: Belongs to the peptidase M10A family.

89673:KCNJ15
gene id: 89673:KCNJ15
uniprot id: A0A7E6D244
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

89673:DLG2
gene id: 89673:DLG2
uniprot id: A0A6J2LQZ2
uniprot id: A0A7E6E373
uniprot id: A0A7E6E3S3
uniprot id: A0A7E6E3V7
uniprot id: A0A7E6E3V9
uniprot id: A0A7E6E4P7
uniprot id: A0A7E6E4U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane

89673:TRAPPC2
gene id: 89673:TRAPPC2
uniprot id: A0A6J2MGD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

89673:COPS3
gene id: 89673:COPS3
uniprot id: A0A6J2NEL3
uniprot id: A0A7E6EAT5
uniprot id: A0A7E6ECC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN3 family.
messages: Cytoplasm
messages: Nucleus

89673:RAD50
gene id: 89673:RAD50
uniprot id: A0A6J2MYY9
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

89673:LOC114498646
gene id: 89673:LOC114498646
uniprot id: A0A6J2LU23
uniprot id: A0A7E6E0F5
names: Subcellular Location Annotation
messages: Cytoplasm

89673:CCNB1
gene id: 89673:CCNB1
uniprot id: A0A6J2MP00
names: Similarity
messages: Belongs to the cyclin family.

89673:LOC114513446
gene id: 89673:LOC114513446
uniprot id: A0A6J2NF58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DPP3
gene id: 89673:DPP3
uniprot id: A0A6J2LW24
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

89673:LOC114511114
gene id: 89673:LOC114511114
uniprot id: A0A7E6CPH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:LOC114512754
gene id: 89673:LOC114512754
uniprot id: A0A6J2NBM1
names: Subcellular Location Annotation
messages: Membrane

89673:TASP1
gene id: 89673:TASP1
uniprot id: A0A6J2MI15
uniprot id: A0A6J2MPA9
uniprot id: A0A7E6CEN5
uniprot id: A0A7E6CEP4
uniprot id: A0A7E6CEU2
uniprot id: A0A7E6CFC2
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

89673:NDST1
gene id: 89673:NDST1
uniprot id: A0A6J2MZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

89673:SESN1
gene id: 89673:SESN1
uniprot id: A0A7E6DHL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

89673:LOC114507823
gene id: 89673:LOC114507823
uniprot id: A0A6J2MQ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MMP16
gene id: 89673:MMP16
uniprot id: A0A6J2M8S3
uniprot id: A0A7E6E6G8
uniprot id: A0A7E6E7L3
names: Similarity
messages: Belongs to the peptidase M10A family.

89673:LOC114509615
gene id: 89673:LOC114509615
uniprot id: A0A6J2MW79
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

89673:HIBCH
gene id: 89673:HIBCH
uniprot id: A0A6J2LEU6
uniprot id: A0A7E6DJ07
uniprot id: A0A7E6DJ25
uniprot id: A0A7E6DJ85
uniprot id: A0A7E6DJ99
uniprot id: A0A7E6DJF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

89673:TRIP10
gene id: 89673:TRIP10
uniprot id: A0A6J2M879
uniprot id: A0A6J2MB11
uniprot id: A0A7E6E954
uniprot id: A0A7E6EA67
uniprot id: A0A7E6EAR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Lysosome
messages: Membrane
messages: cell cortex

89673:EIF4E3
gene id: 89673:EIF4E3
uniprot id: A0A6J2M706
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

89673:NUP205
gene id: 89673:NUP205
uniprot id: A0A6J2MTQ1
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

89673:LOC114500362
gene id: 89673:LOC114500362
uniprot id: A0A7E6DW61
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

89673:CRISP2
gene id: 89673:CRISP2
uniprot id: A0A6J2LDX1
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GPD2
gene id: 89673:GPD2
uniprot id: A0A6J2LBK3
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

89673:LOC114493418
gene id: 89673:LOC114493418
uniprot id: A0A7E6CRB5
names: Similarity
messages: Belongs to the serpin family.

89673:GPRIN2
gene id: 89673:GPRIN2
uniprot id: A0A7E6DTR0
names: Function
messages: May be involved in neurite outgrowth.

89673:NEUROD4
gene id: 89673:NEUROD4
uniprot id: A0A6J2NEQ8
names: Subcellular Location Annotation
messages: Nucleus

89673:SYCE1L
gene id: 89673:SYCE1L
uniprot id: A0A7E6CPX5
names: Similarity
messages: Belongs to the SYCE family.

89673:CHRNE
gene id: 89673:CHRNE
uniprot id: A0A6J2NJ73
uniprot id: A0A7E6ECH5
uniprot id: A0A7E6EDM9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:PPP1R14C
gene id: 89673:PPP1R14C
uniprot id: A0A6J2LI10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.

89673:IDE
gene id: 89673:IDE
uniprot id: A0A6J2LHM6
uniprot id: A0A6J2LIV0
uniprot id: A0A7E6DUN4
uniprot id: A0A7E6DVV6
names: Similarity
messages: Belongs to the peptidase M16 family.

89673:MAN1B1
gene id: 89673:MAN1B1
uniprot id: A0A6J2MV63
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

89673:TCEANC2
gene id: 89673:TCEANC2
uniprot id: A0A6J2LU31
uniprot id: A0A7E6DSS8
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114490327
gene id: 89673:LOC114490327
uniprot id: A0A6J2KZQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PRPF4B
gene id: 89673:PRPF4B
uniprot id: A0A6J2LNA8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

89673:MMP14
gene id: 89673:MMP14
uniprot id: A0A7E6E5D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Cytoplasm
messages: Melanosome

89673:PTHLH
gene id: 89673:PTHLH
uniprot id: A0A6J2NHC0
uniprot id: A0A7E6D752
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the parathyroid hormone family.
messages: Cytoplasm
messages: Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Up-regulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath.
messages: Nucleus
messages: Osteostatin is a potent inhibitor of osteoclastic bone resorption.
messages: PTHrP interacts with PTH1R (via N-terminal extracellular domain).
messages: Secreted
messages: There are several secretory forms, including osteostatin, arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its own receptors that mediates the normal paracrine, autocrine and endocrine actions.

89673:HNRNPU
gene id: 89673:HNRNPU
uniprot id: A0A6J2N3A5
uniprot id: A0A6J2N9M5
uniprot id: A0A7E6CYH3
uniprot id: A0A7E6CYY3
names: Subcellular Location Annotation
messages: Nucleus

89673:RRM2
gene id: 89673:RRM2
uniprot id: A0A6J2LYL9
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

89673:GCHFR
gene id: 89673:GCHFR
uniprot id: A0A6J2LAT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

89673:AMER2
gene id: 89673:AMER2
uniprot id: A0A6J2N7Z1
uniprot id: A0A6J2N9Q4
uniprot id: A0A7E6D7R4
names: Similarity
messages: Belongs to the Amer family.

89673:CDO1
gene id: 89673:CDO1
uniprot id: A0A6J2LUY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

89673:MGAT2
gene id: 89673:MGAT2
uniprot id: A0A6J2L6S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC114500605
gene id: 89673:LOC114500605
uniprot id: A0A6J2M4Z5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PGR
gene id: 89673:PGR
uniprot id: A0A6J2LX80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Cytoplasm
messages: Nucleus
messages: Steroid hormone receptor involved in the regulation of eukaryotic gene expression which affects cellular proliferation and differentiation in target tissues.

89673:F13A1
gene id: 89673:F13A1
uniprot id: A0A6J2LRV5
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

89673:PFDN6
gene id: 89673:PFDN6
uniprot id: A0A6J2LHB9
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

89673:GCNT4
gene id: 89673:GCNT4
uniprot id: A0A6J2NEM4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC114498484
gene id: 89673:LOC114498484
uniprot id: A0A7E6E2U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:KCNE2
gene id: 89673:KCNE2
uniprot id: A0A6J2L2E4
names: Similarity
messages: Belongs to the potassium channel KCNE family.

89673:CCDC58
gene id: 89673:CCDC58
uniprot id: A0A6J2KYC8
uniprot id: A0A7E6D4C9
names: Similarity
messages: Belongs to the MIX23 family.

89673:SLC35E3
gene id: 89673:SLC35E3
uniprot id: A0A6J2NGH7
names: Subcellular Location Annotation
messages: Membrane

89673:PGAP6
gene id: 89673:PGAP6
uniprot id: A0A6J2MCE1
uniprot id: A0A7E6DDP5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:COL4A5
gene id: 89673:COL4A5
uniprot id: A0A7E6D039
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

89673:FXYD5
gene id: 89673:FXYD5
uniprot id: A0A7E6CLD7
uniprot id: A0A7E6CLE3
uniprot id: A0A7E6CLG3
uniprot id: A0A7E6CNK4
names: Similarity
messages: Belongs to the FXYD family.

89673:MAPKAPK2
gene id: 89673:MAPKAPK2
uniprot id: A0A6J2N8W2
uniprot id: A0A7E6CZ87
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114510639
gene id: 89673:LOC114510639
uniprot id: A0A7E6CSS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:PER3
gene id: 89673:PER3
uniprot id: A0A7E6DQS5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:FNTA
gene id: 89673:FNTA
uniprot id: A0A6J2MX23
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

89673:LOC114514997
gene id: 89673:LOC114514997
uniprot id: A0A7E6DFZ8
uniprot id: A0A7E6DG03
uniprot id: A0A7E6DG14
uniprot id: A0A7E6DG57
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

89673:SLC27A2
gene id: 89673:SLC27A2
uniprot id: A0A6J2L9A8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:ALG9
gene id: 89673:ALG9
uniprot id: A0A6J2LV72
uniprot id: A0A7E6DZ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:FOXI2
gene id: 89673:FOXI2
uniprot id: A0A6J2LVH4
names: Subcellular Location Annotation
messages: Nucleus

89673:CHAF1B
gene id: 89673:CHAF1B
uniprot id: A0A6J2KZT2
names: Subcellular Location Annotation
messages: Nucleus

89673:PLIN5
gene id: 89673:PLIN5
uniprot id: A0A6J2M944
names: Similarity
messages: Belongs to the perilipin family.

89673:STAT1
gene id: 89673:STAT1
uniprot id: A0A6J2LBG2
uniprot id: A0A6J2LGG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

89673:ZC3HAV1
gene id: 89673:ZC3HAV1
uniprot id: A0A6J2MUN7
names: Similarity
messages: Belongs to the ARTD/PARP family.

89673:GFRA4
gene id: 89673:GFRA4
uniprot id: A0A7E6CEC1
names: Similarity
messages: Belongs to the GDNFR family.

89673:SS18L1
gene id: 89673:SS18L1
uniprot id: A0A6J2MIG1
names: Similarity
messages: Belongs to the SS18 family.

89673:LUC7L3
gene id: 89673:LUC7L3
uniprot id: A0A6J2MC33
uniprot id: A0A6J2ME82
uniprot id: A0A6J2MEB7
uniprot id: A0A6J2MH76
uniprot id: A0A6J2MI39
uniprot id: A0A7E6EE20
names: Similarity
messages: Belongs to the Luc7 family.

89673:CUEDC2
gene id: 89673:CUEDC2
uniprot id: A0A6J2LRS0
uniprot id: A0A7E6DVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

89673:BRD1
gene id: 89673:BRD1
uniprot id: A0A6J2NFB1
uniprot id: A0A6J2NG00
uniprot id: A0A7E6D8N7
uniprot id: A0A7E6D8R1
uniprot id: A0A7E6D8U1
names: Subcellular Location Annotation
messages: Nucleus

89673:FUT11
gene id: 89673:FUT11
uniprot id: A0A6J2LNS6
uniprot id: A0A7E6DUW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors.

89673:HPD
gene id: 89673:HPD
uniprot id: A0A6J2N0D2
uniprot id: A0A7E6CRU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

89673:GTPBP8
gene id: 89673:GTPBP8
uniprot id: A0A6J2L3Z6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

89673:ST8SIA6
gene id: 89673:ST8SIA6
uniprot id: A0A6J2LBY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:SEPTIN6
gene id: 89673:SEPTIN6
uniprot id: A0A6J2MDA5
uniprot id: A0A6J2MFF5
uniprot id: A0A6J2MFG2
uniprot id: A0A6J2MIM8
uniprot id: A0A6J2MJB3
uniprot id: A0A6J2MJB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

89673:LOC114500357
gene id: 89673:LOC114500357
uniprot id: A0A7E6E512
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

89673:LOC118497855
gene id: 89673:LOC118497855
uniprot id: A0A7E6CRQ5
uniprot id: A0A7E6CUD1
names: Similarity
messages: Belongs to the SLBP family.

89673:INSR
gene id: 89673:INSR
uniprot id: A0A6J2MZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

89673:RPL27A
gene id: 89673:RPL27A
uniprot id: A0A6J2LZ83
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

89673:TMSB15B
gene id: 89673:TMSB15B
uniprot id: A0A7E6CZB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:GRM4
gene id: 89673:GRM4
uniprot id: A0A6J2LLW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

89673:STX5
gene id: 89673:STX5
uniprot id: A0A6J2M2A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

89673:OBSCN
gene id: 89673:OBSCN
uniprot id: A0A7E6EBK1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

89673:SPOPL
gene id: 89673:SPOPL
uniprot id: A0A6J2LC92
names: Similarity
messages: Belongs to the Tdpoz family.

89673:IFNK
gene id: 89673:IFNK
uniprot id: A0A6J2MQV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

89673:LOC114493897
gene id: 89673:LOC114493897
uniprot id: A0A7E6D9K8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114515220
gene id: 89673:LOC114515220
uniprot id: A0A6J2NJF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:BOLA2B
gene id: 89673:BOLA2B
uniprot id: A0A6J2M6Y4
names: Similarity
messages: Belongs to the BolA/IbaG family.

89673:RPS27L
gene id: 89673:RPS27L
uniprot id: A0A6J2L9H6
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

89673:TSPYL2
gene id: 89673:TSPYL2
uniprot id: A0A6J2MK35
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

89673:THBS1
gene id: 89673:THBS1
uniprot id: A0A6J2L2U6
uniprot id: A0A7E6E812
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GPSM1
gene id: 89673:GPSM1
uniprot id: A0A6J2LWD5
uniprot id: A0A6J2M0B5
uniprot id: A0A7E6DGV9
uniprot id: A0A7E6DH38
uniprot id: A0A7E6DH44
names: Similarity
messages: Belongs to the GPSM family.

89673:SLC12A5
gene id: 89673:SLC12A5
uniprot id: A0A6J2MJ37
uniprot id: A0A6J2MQ74
uniprot id: A0A7E6CFN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

89673:CAPN12
gene id: 89673:CAPN12
uniprot id: A0A6J2N777
names: Similarity
messages: Belongs to the peptidase C2 family.

89673:METTL2A
gene id: 89673:METTL2A
uniprot id: A0A6J2M884
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

89673:FAM162B
gene id: 89673:FAM162B
uniprot id: A0A6J2LFK1
uniprot id: A0A6J2LKD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

89673:PTX3
gene id: 89673:PTX3
uniprot id: A0A6J2L0D4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114510145
gene id: 89673:LOC114510145
uniprot id: A0A7E6CUC1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:PHF1
gene id: 89673:PHF1
uniprot id: A0A6J2LAZ8
uniprot id: A0A7E6DL47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

89673:B4GALT6
gene id: 89673:B4GALT6
uniprot id: A0A6J2MSF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

89673:ORM1
gene id: 89673:ORM1
uniprot id: A0A6J2NEY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

89673:EVL
gene id: 89673:EVL
uniprot id: A0A6J2L5V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: lamellipodium
messages: stress fiber

89673:TCEA2
gene id: 89673:TCEA2
uniprot id: A0A6J2MKJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

89673:CDK19
gene id: 89673:CDK19
uniprot id: A0A7E6DMS6
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:ORC3
gene id: 89673:ORC3
uniprot id: A0A6J2LBR2
uniprot id: A0A6J2LGL8
uniprot id: A0A7E6DMY9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

89673:STAG3
gene id: 89673:STAG3
uniprot id: A0A7E6DBE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

89673:POLR3K
gene id: 89673:POLR3K
uniprot id: A0A6J2MAN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

89673:DIPK2B
gene id: 89673:DIPK2B
uniprot id: A0A6J2MGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

89673:BCO2
gene id: 89673:BCO2
uniprot id: A0A7E6DZ10
uniprot id: A0A7E6DZI0
uniprot id: A0A7E6E0B6
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

89673:LOC114498045
gene id: 89673:LOC114498045
uniprot id: A0A6J2LQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRH/QCR6 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

89673:LOC114501604
gene id: 89673:LOC114501604
uniprot id: A0A7E6E431
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:ATP1A3
gene id: 89673:ATP1A3
uniprot id: A0A6J2N145
uniprot id: A0A6J2N2R9
uniprot id: A0A6J2N873
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

89673:PDE1C
gene id: 89673:PDE1C
uniprot id: A0A6J2MR62
uniprot id: A0A6J2MVV9
uniprot id: A0A7E6CHB5
uniprot id: A0A7E6CHN5
uniprot id: A0A7E6CJB6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:LOC114490178
gene id: 89673:LOC114490178
uniprot id: A0A6J2KXF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PADI6
gene id: 89673:PADI6
uniprot id: A0A6J2LI22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Cytoplasm

89673:POFUT1
gene id: 89673:POFUT1
uniprot id: A0A6J2MMJ3
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

89673:LOC114490366
gene id: 89673:LOC114490366
uniprot id: A0A7E6E755
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NCBP1
gene id: 89673:NCBP1
uniprot id: A0A6J2LGY8
uniprot id: A0A6J2LJB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

89673:ABHD2
gene id: 89673:ABHD2
uniprot id: A0A6J2KY47
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

89673:SPON1
gene id: 89673:SPON1
uniprot id: A0A6J2M3K7
names: Subcellular Location Annotation
messages: extracellular matrix

89673:CHMP4A
gene id: 89673:CHMP4A
uniprot id: A0A6J2L5S8
names: Similarity
messages: Belongs to the SNF7 family.

89673:PSMC4
gene id: 89673:PSMC4
uniprot id: A0A6J2N6X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
messages: Cytoplasm

89673:LOC114502885
gene id: 89673:LOC114502885
uniprot id: A0A6J2M8T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

89673:CD82
gene id: 89673:CD82
uniprot id: A0A7E6E0W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:CD6
gene id: 89673:CD6
uniprot id: A0A7E6E1I7
uniprot id: A0A7E6E283
uniprot id: A0A7E6E2Z3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TMEM38A
gene id: 89673:TMEM38A
uniprot id: A0A6J2MCG8
uniprot id: A0A7E6EBS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

89673:VASN
gene id: 89673:VASN
uniprot id: A0A6J2MMB1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GALNS
gene id: 89673:GALNS
uniprot id: A0A6J2KWS6
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfatase family.
messages: Homodimer.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

89673:TTC39A
gene id: 89673:TTC39A
uniprot id: A0A6J2LS20
uniprot id: A0A7E6DSP2
names: Similarity
messages: Belongs to the TTC39 family.

89673:UBE2D3
gene id: 89673:UBE2D3
uniprot id: A0A7E6DSM9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:LOC114496903
gene id: 89673:LOC114496903
uniprot id: A0A7E6DW32
names: Similarity
messages: Belongs to the SAP18 family.

89673:ZP3
gene id: 89673:ZP3
uniprot id: A0A6J2M139
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Membrane
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

89673:TRPC5
gene id: 89673:TRPC5
uniprot id: A0A6J2MFN2
names: Subcellular Location Annotation
messages: Membrane

89673:POLR2D
gene id: 89673:POLR2D
uniprot id: A0A6J2LFI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

89673:TSR1
gene id: 89673:TSR1
uniprot id: A0A6J2M9V8
names: Subcellular Location Annotation
messages: nucleolus

89673:AGAP2
gene id: 89673:AGAP2
uniprot id: A0A6J2N6M6
uniprot id: A0A6J2NB91
uniprot id: A0A7E6D5T4
uniprot id: A0A7E6D8M9
names: Similarity
messages: Belongs to the centaurin gamma-like family.

89673:LOC114512870
gene id: 89673:LOC114512870
uniprot id: A0A6J2NC63
uniprot id: A0A6J2ND32
uniprot id: A0A6J2NEH8
uniprot id: A0A7E6D6G1
names: Similarity
messages: Belongs to the intermediate filament family.

89673:SLC27A5
gene id: 89673:SLC27A5
uniprot id: A0A6J2N1F0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:KHDRBS3
gene id: 89673:KHDRBS3
uniprot id: A0A6J2NCX0
uniprot id: A0A7E6E8C5
names: Similarity
messages: Belongs to the KHDRBS family.

89673:GLP1R
gene id: 89673:GLP1R
uniprot id: A0A6J2LFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

89673:ACOD1
gene id: 89673:ACOD1
uniprot id: A0A6J2MPP3
names: Similarity
messages: Belongs to the PrpD family.

89673:RAB11FIP3
gene id: 89673:RAB11FIP3
uniprot id: A0A6J2LJF6
uniprot id: A0A7E6DDP4
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

89673:IZUMO1R
gene id: 89673:IZUMO1R
uniprot id: A0A6J2M062
names: Similarity
messages: Belongs to the folate receptor family.

89673:NR1H2
gene id: 89673:NR1H2
uniprot id: A0A6J2MZ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

89673:PITHD1
gene id: 89673:PITHD1
uniprot id: A0A6J2LU63
names: Similarity
messages: Belongs to the PITHD1 family.

89673:MAPK1IP1L
gene id: 89673:MAPK1IP1L
uniprot id: A0A6J2L651
names: Similarity
messages: Belongs to the MISS family.

89673:PARG
gene id: 89673:PARG
uniprot id: A0A7E6DWX4
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

89673:LOC114492395
gene id: 89673:LOC114492395
uniprot id: A0A6J2L6D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:METTL26
gene id: 89673:METTL26
uniprot id: A0A6J2LX55
uniprot id: A0A6J2M134
uniprot id: A0A7E6DDP2
names: Similarity
messages: Belongs to the UPF0585 family.

89673:CYHR1
gene id: 89673:CYHR1
uniprot id: A0A6J2NAQ4
names: Similarity
messages: Belongs to the ZFTRAF1 family.

89673:VPS36
gene id: 89673:VPS36
uniprot id: A0A6J2MX36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

89673:SFN
gene id: 89673:SFN
uniprot id: A0A6J2LJ72
names: Similarity
messages: Belongs to the 14-3-3 family.

89673:FEV
gene id: 89673:FEV
uniprot id: A0A6J2LGH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:FGF13
gene id: 89673:FGF13
uniprot id: A0A6J2ME16
uniprot id: A0A6J2MG63
uniprot id: A0A6J2MJF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: dendrite
messages: filopodium
messages: growth cone
messages: sarcolemma

89673:CREB5
gene id: 89673:CREB5
uniprot id: A0A6J2MRA2
uniprot id: A0A6J2MW13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

89673:CMC2
gene id: 89673:CMC2
uniprot id: A0A6J2KSZ7
uniprot id: A0A7E6CMM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

89673:LOC114507474
gene id: 89673:LOC114507474
uniprot id: A0A6J2MNH9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:C7H8orf33
gene id: 89673:C7H8orf33
uniprot id: A0A7E6E9F6
names: Similarity
messages: Belongs to the UPF0488 family.

89673:HTR1F
gene id: 89673:HTR1F
uniprot id: A0A7E6D3I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

89673:NAV3
gene id: 89673:NAV3
uniprot id: A0A6J2NDL3
uniprot id: A0A7E6D5L7
uniprot id: A0A7E6D8D9
names: Similarity
messages: Belongs to the Nav/unc-53 family.

89673:INPP5K
gene id: 89673:INPP5K
uniprot id: A0A6J2MBA5
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

89673:LOC114511328
gene id: 89673:LOC114511328
uniprot id: A0A6J2N1W4
uniprot id: A0A6J2N6H4
uniprot id: A0A7E6CPS8
uniprot id: A0A7E6CQ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration.
messages: cytoskeleton

89673:LOC114503780
gene id: 89673:LOC114503780
uniprot id: A0A6J2MD23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114506793
gene id: 89673:LOC114506793
uniprot id: A0A7E6CGK3
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

89673:CDC25B
gene id: 89673:CDC25B
uniprot id: A0A6J2MLY5
uniprot id: A0A7E6CER8
uniprot id: A0A7E6CES7
uniprot id: A0A7E6CFF1
uniprot id: A0A7E6CGZ6
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

89673:NEDD8
gene id: 89673:NEDD8
uniprot id: A0A6J2L447
names: Similarity
messages: Belongs to the ubiquitin family.

89673:LOC114500245
gene id: 89673:LOC114500245
uniprot id: A0A6J2M399
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ROMO1
gene id: 89673:ROMO1
uniprot id: A0A6J2MKS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

89673:DYNLL2
gene id: 89673:DYNLL2
uniprot id: A0A6J2MBI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

89673:LOC114512997
gene id: 89673:LOC114512997
uniprot id: A0A6J2N7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:S1PR2
gene id: 89673:S1PR2
uniprot id: A0A6J2M8Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

89673:STIM2
gene id: 89673:STIM2
uniprot id: A0A7E6D8E2
uniprot id: A0A7E6D900
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:ATG4C
gene id: 89673:ATG4C
uniprot id: A0A7E6DTJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

89673:TIMM22
gene id: 89673:TIMM22
uniprot id: A0A6J2ME56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

89673:KRT71
gene id: 89673:KRT71
uniprot id: A0A6J2N8P2
uniprot id: A0A7E6D6K7
names: Similarity
messages: Belongs to the intermediate filament family.

89673:EPB41L5
gene id: 89673:EPB41L5
uniprot id: A0A6J2NBI1
uniprot id: A0A6J2NHG6
uniprot id: A0A7E6DK84
uniprot id: A0A7E6DK86
uniprot id: A0A7E6DK88
uniprot id: A0A7E6DKI8
uniprot id: A0A7E6DKJ2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Photoreceptor inner segment
messages: Plays a role in the formation and organization of tight junctions during the establishment of polarity in epithelial cells.

89673:LOC114493261
gene id: 89673:LOC114493261
uniprot id: A0A6J2L9V4
names: Function
names: Subcellular Location Annotation
messages: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
messages: Secreted

89673:APOH
gene id: 89673:APOH
uniprot id: A0A6J2MBD7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:KIF3B
gene id: 89673:KIF3B
uniprot id: A0A6J2MK00
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:CERS6
gene id: 89673:CERS6
uniprot id: A0A6J2LFX6
uniprot id: A0A6J2LIG3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

89673:ZNF280C
gene id: 89673:ZNF280C
uniprot id: A0A6J2MG65
uniprot id: A0A6J2MJN6
uniprot id: A0A7E6D117
uniprot id: A0A7E6D3M6
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

89673:TSPAN2
gene id: 89673:TSPAN2
uniprot id: A0A6J2KTN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:NAIF1
gene id: 89673:NAIF1
uniprot id: A0A6J2M266
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

89673:MINPP1
gene id: 89673:MINPP1
uniprot id: A0A6J2LPL1
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

89673:LOC114489505
gene id: 89673:LOC114489505
uniprot id: A0A6J2KUL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:TTC39C
gene id: 89673:TTC39C
uniprot id: A0A6J2MK72
names: Similarity
messages: Belongs to the TTC39 family.

89673:MOS
gene id: 89673:MOS
uniprot id: A0A6J2ND93
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:ARRB2
gene id: 89673:ARRB2
uniprot id: A0A6J2NC00
uniprot id: A0A6J2NDM1
uniprot id: A0A7E6EBR3
uniprot id: A0A7E6EBS0
uniprot id: A0A7E6EDD5
names: Similarity
messages: Belongs to the arrestin family.

89673:AZIN1
gene id: 89673:AZIN1
uniprot id: A0A6J2NB12
uniprot id: A0A6J2NCP8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

89673:LOC114508036
gene id: 89673:LOC114508036
uniprot id: A0A7E6DCH5
uniprot id: A0A7E6DD75
names: Similarity
messages: Belongs to the mesothelin family.

89673:NQO2
gene id: 89673:NQO2
uniprot id: A0A6J2LQQ6
uniprot id: A0A7E6DTF0
uniprot id: A0A7E6DTJ8
uniprot id: A0A7E6DU80
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

89673:CDH12
gene id: 89673:CDH12
uniprot id: A0A6J2LR42
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:NCLN
gene id: 89673:NCLN
uniprot id: A0A6J2MBI3
uniprot id: A0A6J2MHK1
names: Function
names: Similarity
messages: Belongs to the nicastrin family.
messages: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.

89673:LOC114500255
gene id: 89673:LOC114500255
uniprot id: A0A6J2LZD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114515265
gene id: 89673:LOC114515265
uniprot id: A0A7E6ECM6
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

89673:C8G
gene id: 89673:C8G
uniprot id: A0A7E6DH14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

89673:PCYOX1L
gene id: 89673:PCYOX1L
uniprot id: A0A6J2N373
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

89673:LOC114514975
gene id: 89673:LOC114514975
uniprot id: A0A6J2NII5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TFAP2E
gene id: 89673:TFAP2E
uniprot id: A0A6J2LUE5
names: Similarity
messages: Belongs to the AP-2 family.

89673:LOC114497386
gene id: 89673:LOC114497386
uniprot id: A0A6J2LSL7
names: Similarity
messages: Belongs to the CLCR family.

89673:HERC4
gene id: 89673:HERC4
uniprot id: A0A7E6DU90
uniprot id: A0A7E6DUU5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:KRT20
gene id: 89673:KRT20
uniprot id: A0A7E6EEG5
names: Similarity
messages: Belongs to the intermediate filament family.

89673:RPL11
gene id: 89673:RPL11
uniprot id: A0A6J2LJM0
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

89673:LOC114504888
gene id: 89673:LOC114504888
uniprot id: A0A7E6D211
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

89673:FICD
gene id: 89673:FICD
uniprot id: A0A6J2MU03
names: Similarity
messages: Belongs to the fic family.

89673:LOC114488977
gene id: 89673:LOC114488977
uniprot id: A0A7E6CW61
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

89673:TH
gene id: 89673:TH
uniprot id: A0A6J2LZH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region
messages: synaptic vesicle

89673:ACAP1
gene id: 89673:ACAP1
uniprot id: A0A6J2NJI6
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

89673:DDB2
gene id: 89673:DDB2
uniprot id: A0A6J2LXR2
uniprot id: A0A7E6E2I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

89673:ST8SIA2
gene id: 89673:ST8SIA2
uniprot id: A0A6J2KSH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:OTX1
gene id: 89673:OTX1
uniprot id: A0A6J2M4W1
uniprot id: A0A7E6DXH5
uniprot id: A0A7E6DYG0
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114497442
gene id: 89673:LOC114497442
uniprot id: A0A7E6DRF8
uniprot id: A0A7E6DSK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:CD79A
gene id: 89673:CD79A
uniprot id: A0A6J2N8A7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:LOC114491868
gene id: 89673:LOC114491868
uniprot id: A0A6J2L536
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-casein family.
messages: Important role in determination of the surface properties of the casein micelles.
messages: Secreted

89673:PKP3
gene id: 89673:PKP3
uniprot id: A0A6J2M1T9
names: Similarity
messages: Belongs to the beta-catenin family.

89673:OSBPL10
gene id: 89673:OSBPL10
uniprot id: A0A6J2M371
uniprot id: A0A6J2M4Q8
names: Similarity
messages: Belongs to the OSBP family.

89673:QTRT2
gene id: 89673:QTRT2
uniprot id: A0A6J2L5L6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

89673:RNPS1
gene id: 89673:RNPS1
uniprot id: A0A6J2LM07
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the splicing factor SR family.
messages: Found in mRNA splicing-dependent exon junction complexes (EJC). Found in a post-splicing complex with NXF1, RBM8A, UPF1, UPF2, UPF3A, UPF3B and RNPS1. Component of the heterotrimeric ASAP (apoptosis- and splicing-associated protein) and PSAP complexes consisting of RNPS1, SAP18 and either ACIN1 or PNN, respectively; the ASAP and PSAP complexes probably are formed mutually exclusive. Component of the active spliceosome. Associates with polysomes. Interacts with the cleaved p110 isoform of CDC2L1, CSNK2A1, PNN, SART3, SRP54, SRRM1 and TRA2B/SFRS10.
messages: Nucleus speckle

89673:UNC45B
gene id: 89673:UNC45B
uniprot id: A0A6J2M881
names: Subcellular Location Annotation
messages: A band
messages: Z line
messages: perinuclear region

89673:SORCS3
gene id: 89673:SORCS3
uniprot id: A0A6J2LQ40
uniprot id: A0A7E6DVG2
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

89673:ZDHHC15
gene id: 89673:ZDHHC15
uniprot id: A0A6J2ME05
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:LOC114515372
gene id: 89673:LOC114515372
uniprot id: A0A7E6EFG0
names: Similarity
messages: Belongs to the NAC-beta family.

89673:LOC114497141
gene id: 89673:LOC114497141
uniprot id: A0A6J2LMJ8
names: Similarity
messages: Belongs to the annexin family.

89673:SLC50A1
gene id: 89673:SLC50A1
uniprot id: A0A6J2KXM1
uniprot id: A0A7E6CWL6
uniprot id: A0A7E6CX47
uniprot id: A0A7E6CZA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates sugar transport across membranes.
messages: Membrane

89673:LOC114490560
gene id: 89673:LOC114490560
uniprot id: A0A6J2KYV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

89673:POLR2K
gene id: 89673:POLR2K
uniprot id: A0A6J2NI24
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

89673:GNA15
gene id: 89673:GNA15
uniprot id: A0A6J2M7L9
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

89673:TMBIM4
gene id: 89673:TMBIM4
uniprot id: A0A6J2N923
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

89673:CDK8
gene id: 89673:CDK8
uniprot id: A0A6J2KWS8
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114511882
gene id: 89673:LOC114511882
uniprot id: A0A6J2N222
uniprot id: A0A7E6CXK7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CLIC6
gene id: 89673:CLIC6
uniprot id: A0A6J2L0C7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

89673:TLX3
gene id: 89673:TLX3
uniprot id: A0A6J2MWJ3
names: Subcellular Location Annotation
messages: Nucleus

89673:SLC49A3
gene id: 89673:SLC49A3
uniprot id: A0A6J2L1X1
uniprot id: A0A7E6D2X3
names: Subcellular Location Annotation
messages: Membrane

89673:LOC118496709
gene id: 89673:LOC118496709
uniprot id: A0A7E6CDT4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

89673:SLC26A2
gene id: 89673:SLC26A2
uniprot id: A0A6J2N043
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Membrane
messages: Sulfate transporter. May play a role in endochondral bone formation.

89673:MANF
gene id: 89673:MANF
uniprot id: A0A6J2M1U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

89673:PIGK
gene id: 89673:PIGK
uniprot id: A0A6J2LLR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Endoplasmic reticulum membrane
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

89673:CKB
gene id: 89673:CKB
uniprot id: A0A6J2L7T0
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

89673:VAX2
gene id: 89673:VAX2
uniprot id: A0A6J2M1I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMX homeobox family.
messages: Nucleus

89673:GJE1
gene id: 89673:GJE1
uniprot id: A0A6J2LGF2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:HECTD3
gene id: 89673:HECTD3
uniprot id: A0A7E6DRN4
uniprot id: A0A7E6DSD7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RAMP2
gene id: 89673:RAMP2
uniprot id: A0A6J2MBT5
uniprot id: A0A6J2MF66
uniprot id: A0A7E6EE09
uniprot id: A0A7E6EFL6
uniprot id: A0A7E6EFS6
names: Similarity
messages: Belongs to the RAMP family.

89673:LOC118496961
gene id: 89673:LOC118496961
uniprot id: A0A7E6CH29
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ETNPPL
gene id: 89673:ETNPPL
uniprot id: A0A6J2L6H5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

89673:PCNX3
gene id: 89673:PCNX3
uniprot id: A0A6J2LTS4
uniprot id: A0A7E6E434
uniprot id: A0A7E6E4Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

89673:TRMT13
gene id: 89673:TRMT13
uniprot id: A0A6J2KZU5
uniprot id: A0A7E6CXD1
uniprot id: A0A7E6CZY9
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

89673:NFX1
gene id: 89673:NFX1
uniprot id: A0A6J2LF28
uniprot id: A0A7E6DFF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

89673:PDRG1
gene id: 89673:PDRG1
uniprot id: A0A6J2MJH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

89673:PKD2L1
gene id: 89673:PKD2L1
uniprot id: A0A7E6DUZ1
uniprot id: A0A7E6DVJ6
uniprot id: A0A7E6DVW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane
messages: cilium membrane

89673:PLK1
gene id: 89673:PLK1
uniprot id: A0A6J2MDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: Midbody
messages: Nucleus
messages: centrosome

89673:PLAC8
gene id: 89673:PLAC8
uniprot id: A0A6J2LBR4
names: Similarity
messages: Belongs to the cornifelin family.

89673:CCDC167
gene id: 89673:CCDC167
uniprot id: A0A6J2LER7
uniprot id: A0A7E6DLF0
uniprot id: A0A7E6DM59
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114513353
gene id: 89673:LOC114513353
uniprot id: A0A6J2N7C5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:MYO1F
gene id: 89673:MYO1F
uniprot id: A0A6J2ME60
uniprot id: A0A7E6EB54
uniprot id: A0A7E6EBB5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:WDR4
gene id: 89673:WDR4
uniprot id: A0A6J2KZ12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit METTL1.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

89673:LOC114497059
gene id: 89673:LOC114497059
uniprot id: A0A7E6DXE4
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:LOC114509802
gene id: 89673:LOC114509802
uniprot id: A0A6J2MVE8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ZC3H14
gene id: 89673:ZC3H14
uniprot id: A0A6J2L3I5
uniprot id: A0A6J2L468
uniprot id: A0A6J2L5U5
uniprot id: A0A6J2L5V0
uniprot id: A0A6J2L9I9
uniprot id: A0A7E6CPJ6
uniprot id: A0A7E6CPS1
uniprot id: A0A7E6CPU5
uniprot id: A0A7E6CRX6
uniprot id: A0A7E6CRZ6
uniprot id: A0A7E6CS00
uniprot id: A0A7E6CS33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

89673:VPS26B
gene id: 89673:VPS26B
uniprot id: A0A6J2N190
names: Similarity
messages: Belongs to the VPS26 family.

89673:PTAFR
gene id: 89673:PTAFR
uniprot id: A0A7E6DRD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

89673:ZCCHC4
gene id: 89673:ZCCHC4
uniprot id: A0A6J2L541
uniprot id: A0A7E6D821
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC4 family.
messages: Cytoplasm
messages: nucleolus

89673:MDH2
gene id: 89673:MDH2
uniprot id: A0A6J2MJ05
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

89673:SGCZ
gene id: 89673:SGCZ
uniprot id: A0A6J2MY43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

89673:DNAJC2
gene id: 89673:DNAJC2
uniprot id: A0A7E6CGQ3
names: Function
messages: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.

89673:MSRB1
gene id: 89673:MSRB1
uniprot id: A0A6J2M1L7
uniprot id: A0A7E6DC23
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.

89673:MANBAL
gene id: 89673:MANBAL
uniprot id: A0A6J2MKW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

89673:STOM
gene id: 89673:STOM
uniprot id: A0A6J2LAF8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

89673:PAX2
gene id: 89673:PAX2
uniprot id: A0A6J2LK17
uniprot id: A0A6J2LK22
uniprot id: A0A6J2LLA1
uniprot id: A0A6J2LQ42
uniprot id: A0A6J2LQ48
uniprot id: A0A6J2LQG2
uniprot id: A0A6J2LQG6
names: Subcellular Location Annotation
messages: Nucleus

89673:PDGFD
gene id: 89673:PDGFD
uniprot id: A0A6J2M0W8
uniprot id: A0A6J2M4N7
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Homodimer; disulfide-linked. Interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ACTR8
gene id: 89673:ACTR8
uniprot id: A0A6J2M2C4
uniprot id: A0A7E6E6X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

89673:EMX2
gene id: 89673:EMX2
uniprot id: A0A6J2LVW7
names: Subcellular Location Annotation
messages: Nucleus

89673:MED7
gene id: 89673:MED7
uniprot id: A0A6J2MWL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

89673:ADAM17
gene id: 89673:ADAM17
uniprot id: A0A6J2LTT0
uniprot id: A0A6J2LUY7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114509996
gene id: 89673:LOC114509996
uniprot id: A0A6J2MXY4
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:TIMM44
gene id: 89673:TIMM44
uniprot id: A0A6J2NJF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

89673:ZADH2
gene id: 89673:ZADH2
uniprot id: A0A6J2ML94
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

89673:PIP4P2
gene id: 89673:PIP4P2
uniprot id: A0A6J2M4K4
uniprot id: A0A6J2M7C5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

89673:LOC114489398
gene id: 89673:LOC114489398
uniprot id: A0A6J2KWV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:TUBA1C
gene id: 89673:TUBA1C
uniprot id: A0A6J2N7Q3
uniprot id: A0A7E6D6S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

89673:NEK7
gene id: 89673:NEK7
uniprot id: A0A6J2N5A0
uniprot id: A0A7E6D141
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:ZNF449
gene id: 89673:ZNF449
uniprot id: A0A6J2MHH0
names: Subcellular Location Annotation
messages: Nucleus

89673:NUPR1
gene id: 89673:NUPR1
uniprot id: A0A6J2MH99
names: Similarity
messages: Belongs to the NUPR family.

89673:CAPN13
gene id: 89673:CAPN13
uniprot id: A0A6J2M1X5
names: Similarity
messages: Belongs to the peptidase C2 family.

89673:SLC19A1
gene id: 89673:SLC19A1
uniprot id: A0A6J2KXS8
uniprot id: A0A6J2KZH9
uniprot id: A0A7E6D2C1
uniprot id: A0A7E6D553
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

89673:RRM1
gene id: 89673:RRM1
uniprot id: A0A6J2LT53
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

89673:LOC114490186
gene id: 89673:LOC114490186
uniprot id: A0A6J2KZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CDH3
gene id: 89673:CDH3
uniprot id: A0A6J2KS74
uniprot id: A0A6J2KTV7
uniprot id: A0A6J2KW36
uniprot id: A0A7E6CM54
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:ARAP1
gene id: 89673:ARAP1
uniprot id: A0A6J2LTS5
uniprot id: A0A7E6E129
names: Subcellular Location Annotation
messages: Cytoplasm

89673:GGA1
gene id: 89673:GGA1
uniprot id: A0A6J2N8A4
uniprot id: A0A7E6D8A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

89673:TLE7
gene id: 89673:TLE7
uniprot id: A0A7E6CTR2
names: Similarity
messages: Belongs to the WD repeat Groucho/TLE family.

89673:SPATS2L
gene id: 89673:SPATS2L
uniprot id: A0A6J2LE01
uniprot id: A0A7E6DJA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPATS2 family.
messages: Cytoplasm

89673:MID1IP1
gene id: 89673:MID1IP1
uniprot id: A0A6J2MIG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

89673:ST8SIA1
gene id: 89673:ST8SIA1
uniprot id: A0A6J2N724
uniprot id: A0A7E6D7F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:BRINP1
gene id: 89673:BRINP1
uniprot id: A0A6J2MYH1
names: Similarity
messages: Belongs to the BRINP family.

89673:LOC114503202
gene id: 89673:LOC114503202
uniprot id: A0A6J2MAQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

89673:LOC114507451
gene id: 89673:LOC114507451
uniprot id: A0A6J2MNG8
uniprot id: A0A7E6CJ53
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:RC3H2
gene id: 89673:RC3H2
uniprot id: A0A6J2LD51
uniprot id: A0A6J2LD64
uniprot id: A0A6J2LED5
names: Subcellular Location Annotation
messages: P-body

89673:TAS2R4
gene id: 89673:TAS2R4
uniprot id: A0A7E6CIR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane
messages: cilium membrane

89673:GNB5
gene id: 89673:GNB5
uniprot id: A0A6J2L7I4
uniprot id: A0A7E6ED45
uniprot id: A0A7E6EDT5
uniprot id: A0A7E6EEM9
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

89673:APLN
gene id: 89673:APLN
uniprot id: A0A6J2MI34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apelin family.
messages: extracellular space

89673:DLX6
gene id: 89673:DLX6
uniprot id: A0A6J2MPM7
names: Subcellular Location Annotation
messages: Nucleus

89673:KCNK5
gene id: 89673:KCNK5
uniprot id: A0A6J2LJ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

89673:CRX
gene id: 89673:CRX
uniprot id: A0A6J2N5W5
names: Subcellular Location Annotation
messages: Nucleus

89673:NOP56
gene id: 89673:NOP56
uniprot id: A0A7E6CEX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

89673:MUC2
gene id: 89673:MUC2
uniprot id: A0A6J2LYN6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:IL17F
gene id: 89673:IL17F
uniprot id: A0A6J2LE54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

89673:CLIC2
gene id: 89673:CLIC2
uniprot id: A0A6J2MGE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

89673:LOC114512652
gene id: 89673:LOC114512652
uniprot id: A0A6J2N4G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:TAF9B
gene id: 89673:TAF9B
uniprot id: A0A6J2MGC2
uniprot id: A0A7E6CZP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

89673:LOC114490340
gene id: 89673:LOC114490340
uniprot id: A0A7E6E6C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DIAPH1
gene id: 89673:DIAPH1
uniprot id: A0A6J2MUC4
uniprot id: A0A6J2MYX0
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

89673:ACVR1
gene id: 89673:ACVR1
uniprot id: A0A6J2LAK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

89673:STRIP2
gene id: 89673:STRIP2
uniprot id: A0A6J2MQY8
uniprot id: A0A7E6CIJ0
uniprot id: A0A7E6CIY7
names: Similarity
messages: Belongs to the STRIP family.

89673:DIP2B
gene id: 89673:DIP2B
uniprot id: A0A6J2NHA4
uniprot id: A0A7E6D6P7
uniprot id: A0A7E6D6T3
names: Similarity
messages: Belongs to the DIP2 family.

89673:PPARD
gene id: 89673:PPARD
uniprot id: A0A6J2LDA6
uniprot id: A0A6J2LI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

89673:PDX1
gene id: 89673:PDX1
uniprot id: A0A6J2L0B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:TBX20
gene id: 89673:TBX20
uniprot id: A0A6J2MQR3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:IL17B
gene id: 89673:IL17B
uniprot id: A0A6J2MYE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

89673:SHH
gene id: 89673:SHH
uniprot id: A0A6J2MQ69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

89673:ATP6V0C
gene id: 89673:ATP6V0C
uniprot id: A0A6J2LHA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

89673:QRSL1
gene id: 89673:QRSL1
uniprot id: A0A6J2LGS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

89673:MGAM
gene id: 89673:MGAM
uniprot id: A0A7E6CJ18
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114506915
gene id: 89673:LOC114506915
uniprot id: A0A6J2MKJ5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

89673:CHRNG
gene id: 89673:CHRNG
uniprot id: A0A6J2LFB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:C5H10orf53
gene id: 89673:C5H10orf53
uniprot id: A0A6J2LH54
names: Similarity
messages: Belongs to the UPF0728 family.

89673:JPH4
gene id: 89673:JPH4
uniprot id: A0A6J2L9D9
uniprot id: A0A7E6E403
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

89673:STEAP3
gene id: 89673:STEAP3
uniprot id: A0A6J2NBV8
uniprot id: A0A7E6DKA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

89673:MFAP2
gene id: 89673:MFAP2
uniprot id: A0A6J2LML4
uniprot id: A0A6J2LNX6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:HOXB2
gene id: 89673:HOXB2
uniprot id: A0A6J2MH56
uniprot id: A0A7E6EFF7
names: Subcellular Location Annotation
messages: Nucleus

89673:HOXB4
gene id: 89673:HOXB4
uniprot id: A0A6J2MEX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:RP2
gene id: 89673:RP2
uniprot id: A0A6J2MHU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

89673:IL12B
gene id: 89673:IL12B
uniprot id: A0A6J2N2T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

89673:FMR1
gene id: 89673:FMR1
uniprot id: A0A6J2MHX5
uniprot id: A0A6J2MIB6
uniprot id: A0A6J2MLR1
uniprot id: A0A7E6D034
uniprot id: A0A7E6D0C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cell membrane
messages: Cytoplasmic ribonucleoprotein granule
messages: Membrane
messages: Perikaryon
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: centromere
messages: dendrite
messages: dendritic spine
messages: filopodium tip
messages: growth cone
messages: neuron projection
messages: nucleolus
messages: perinuclear region
messages: synaptosome

89673:SEC23A
gene id: 89673:SEC23A
uniprot id: A0A6J2L2Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

89673:LOC114490026
gene id: 89673:LOC114490026
uniprot id: A0A6J2KWX5
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

89673:NUP62
gene id: 89673:NUP62
uniprot id: A0A6J2N086
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

89673:LOC118500937
gene id: 89673:LOC118500937
uniprot id: A0A7E6DWU3
names: Function
names: Subcellular Location Annotation
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides.
messages: Membrane raft
messages: phagosome membrane

89673:AP1S1
gene id: 89673:AP1S1
uniprot id: A0A6J2LDB1
uniprot id: A0A6J2LEC4
uniprot id: A0A6J2LI28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

89673:MATK
gene id: 89673:MATK
uniprot id: A0A6J2M9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:GNB2
gene id: 89673:GNB2
uniprot id: A0A6J2LJ44
uniprot id: A0A6J2LNK2
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

89673:LOC114510120
gene id: 89673:LOC114510120
uniprot id: A0A6J2N3U0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PRRC1
gene id: 89673:PRRC1
uniprot id: A0A6J2MPR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRRC1 family.
messages: Golgi apparatus

89673:IMMT
gene id: 89673:IMMT
uniprot id: A0A6J2LUP1
uniprot id: A0A6J2LVL6
uniprot id: A0A6J2LYJ2
uniprot id: A0A7E6DYM1
uniprot id: A0A7E6DZ41
uniprot id: A0A7E6DZH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

89673:LOC114499275
gene id: 89673:LOC114499275
uniprot id: A0A6J2LVS8
names: Similarity
messages: Belongs to the FAM178 family.

89673:EDA2R
gene id: 89673:EDA2R
uniprot id: A0A6J2MG21
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ADGRF5
gene id: 89673:ADGRF5
uniprot id: A0A6J2LEG1
uniprot id: A0A6J2LI07
uniprot id: A0A7E6DLT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

89673:MAP2K4
gene id: 89673:MAP2K4
uniprot id: A0A6J2NBS0
uniprot id: A0A6J2NII2
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114500440
gene id: 89673:LOC114500440
uniprot id: A0A6J2M0Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ALDH2
gene id: 89673:ALDH2
uniprot id: A0A6J2N1D4
uniprot id: A0A7E6CX25
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

89673:LECT2
gene id: 89673:LECT2
uniprot id: A0A6J2N4E1
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

89673:C2H3orf70
gene id: 89673:C2H3orf70
uniprot id: A0A6J2L076
names: Similarity
messages: Belongs to the UPF0524 family.

89673:CDC42EP1
gene id: 89673:CDC42EP1
uniprot id: A0A6J2NCN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

89673:LOC114505596
gene id: 89673:LOC114505596
uniprot id: A0A6J2MIT0
uniprot id: A0A6J2MMU8
uniprot id: A0A7E6DC58
uniprot id: A0A7E6DD22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM16/PAM16 family.
messages: Belongs to the WD repeat coronin family.
messages: Cytoplasmic vesicle
messages: F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology.
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicle
messages: cytosol
messages: trans-Golgi network

89673:MAP7D1
gene id: 89673:MAP7D1
uniprot id: A0A6J2LI19
uniprot id: A0A6J2LKD9
uniprot id: A0A6J2LMZ3
uniprot id: A0A7E6DRW5
names: Similarity
messages: Belongs to the MAP7 family.

89673:CENPJ
gene id: 89673:CENPJ
uniprot id: A0A7E6D5I0
names: Similarity
messages: Belongs to the TCP10 family.

89673:CR1
gene id: 89673:CR1
uniprot id: A0A7E6CVG1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:EFNA1
gene id: 89673:EFNA1
uniprot id: A0A6J2KZY0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:BDH1
gene id: 89673:BDH1
uniprot id: A0A6J2KYI3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:NKAPL
gene id: 89673:NKAPL
uniprot id: A0A6J2KXA2
names: Similarity
messages: Belongs to the NKAP family.

89673:LOC114490520
gene id: 89673:LOC114490520
uniprot id: A0A6J2KY39
uniprot id: A0A7E6D657
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

89673:VPS33B
gene id: 89673:VPS33B
uniprot id: A0A6J2KVA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

89673:LOC114500244
gene id: 89673:LOC114500244
uniprot id: A0A6J2M088
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC6A11
gene id: 89673:SLC6A11
uniprot id: A0A6J2M9G8
uniprot id: A0A7E6E5U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

89673:TMEM41A
gene id: 89673:TMEM41A
uniprot id: A0A6J2L605
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

89673:NR5A1
gene id: 89673:NR5A1
uniprot id: A0A6J2MB08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

89673:USP30
gene id: 89673:USP30
uniprot id: A0A6J2MXY9
uniprot id: A0A6J2N389
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

89673:LOC114488676
gene id: 89673:LOC114488676
uniprot id: A0A7E6DFX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ASPH
gene id: 89673:ASPH
uniprot id: A0A6J2NC04
uniprot id: A0A6J2NGU6
uniprot id: A0A7E6E624
uniprot id: A0A7E6E631
uniprot id: A0A7E6E636
uniprot id: A0A7E6E6M0
uniprot id: A0A7E6E6M5
uniprot id: A0A7E6E6Y7
uniprot id: A0A7E6E6Z1
uniprot id: A0A7E6E7K9
uniprot id: A0A7E6E7L7
uniprot id: A0A7E6E7M1
uniprot id: A0A7E6E7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

89673:AQP10
gene id: 89673:AQP10
uniprot id: A0A6J2KU05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

89673:ZNF706
gene id: 89673:ZNF706
uniprot id: A0A6J2NHY0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:GBA
gene id: 89673:GBA
uniprot id: A0A6J2KY58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

89673:TYW3
gene id: 89673:TYW3
uniprot id: A0A6J2LT01
uniprot id: A0A7E6DSL7
uniprot id: A0A7E6DSR5
uniprot id: A0A7E6DT78
uniprot id: A0A7E6DTT5
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

89673:ING3
gene id: 89673:ING3
uniprot id: A0A6J2MTN1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

89673:CLTA
gene id: 89673:CLTA
uniprot id: A0A6J2LDM6
uniprot id: A0A6J2LEK3
uniprot id: A0A6J2LFS5
uniprot id: A0A6J2LFU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

89673:COL4A2
gene id: 89673:COL4A2
uniprot id: A0A6J2MQM3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

89673:CHRDL2
gene id: 89673:CHRDL2
uniprot id: A0A6J2LXH0
names: Subcellular Location Annotation
messages: Secreted

89673:PI4KB
gene id: 89673:PI4KB
uniprot id: A0A6J2KSM6
uniprot id: A0A6J2KT81
uniprot id: A0A6J2KYM0
uniprot id: A0A6J2KYM6
uniprot id: A0A7E6CW56
uniprot id: A0A7E6CYR5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

89673:TRIQK
gene id: 89673:TRIQK
uniprot id: A0A6J2NIQ6
uniprot id: A0A7E6E6W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114498926
gene id: 89673:LOC114498926
uniprot id: A0A6J2LTS7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC47A2
gene id: 89673:SLC47A2
uniprot id: A0A7E6EBS4
uniprot id: A0A7E6EBV0
uniprot id: A0A7E6ECW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

89673:CASTOR2
gene id: 89673:CASTOR2
uniprot id: A0A6J2LZZ7
names: Similarity
messages: Belongs to the GATS family.

89673:TSPAN19
gene id: 89673:TSPAN19
uniprot id: A0A6J2NBN7
uniprot id: A0A7E6D5E9
uniprot id: A0A7E6D5G7
uniprot id: A0A7E6D5J9
uniprot id: A0A7E6D639
uniprot id: A0A7E6D8A1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:OXR1
gene id: 89673:OXR1
uniprot id: A0A6J2NBJ7
uniprot id: A0A6J2NDM5
uniprot id: A0A6J2NID5
uniprot id: A0A6J2NIX8
uniprot id: A0A7E6E6M7
uniprot id: A0A7E6E6N1
uniprot id: A0A7E6E846
uniprot id: A0A7E6E8F6
uniprot id: A0A7E6E8G1
names: Similarity
messages: Belongs to the OXR1 family.

89673:LOC114500670
gene id: 89673:LOC114500670
uniprot id: A0A6J2M1R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

89673:DCTD
gene id: 89673:DCTD
uniprot id: A0A6J2MSI3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

89673:MYLK4
gene id: 89673:MYLK4
uniprot id: A0A7E6DTL0
uniprot id: A0A7E6DU96
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:XIRP1
gene id: 89673:XIRP1
uniprot id: A0A6J2M0Q4
names: Domain
names: Function
names: Similarity
messages: Belongs to the Xin family.
messages: Protects actin filaments from depolymerization.
messages: Xin repeats bind F-actin.

89673:PLA2G1B
gene id: 89673:PLA2G1B
uniprot id: A0A6J2MTS0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

89673:PUS3
gene id: 89673:PUS3
uniprot id: A0A6J2MWJ2
uniprot id: A0A7E6CV69
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

89673:MAPK9
gene id: 89673:MAPK9
uniprot id: A0A6J2N0V0
uniprot id: A0A7E6CU62
uniprot id: A0A7E6CV01
uniprot id: A0A7E6CWZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

89673:ZFX
gene id: 89673:ZFX
uniprot id: A0A6J2MFN3
uniprot id: A0A6J2MFS5
uniprot id: A0A6J2MJN7
uniprot id: A0A7E6D031
names: Subcellular Location Annotation
messages: Nucleus

89673:MSRB2
gene id: 89673:MSRB2
uniprot id: A0A6J2L9Z3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

89673:THBS2
gene id: 89673:THBS2
uniprot id: A0A7E6DNY5
uniprot id: A0A7E6DQ08
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:KCTD3
gene id: 89673:KCTD3
uniprot id: A0A6J2N526
names: Similarity
messages: Belongs to the KCTD3 family.

89673:AHDC1
gene id: 89673:AHDC1
uniprot id: A0A6J2LRP8
names: Subcellular Location Annotation
messages: Nucleus

89673:INS
gene id: 89673:INS
uniprot id: A0A6J2M1G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

89673:MYO1B
gene id: 89673:MYO1B
uniprot id: A0A6J2LAA5
uniprot id: A0A6J2LEW1
uniprot id: A0A7E6DIZ1
uniprot id: A0A7E6DJ08
uniprot id: A0A7E6DJ12
uniprot id: A0A7E6DJ70
uniprot id: A0A7E6DJ83
uniprot id: A0A7E6DJD6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:LOC118496637
gene id: 89673:LOC118496637
uniprot id: A0A7E6E496
names: Similarity
messages: Belongs to the FAM178 family.

89673:KCNE4
gene id: 89673:KCNE4
uniprot id: A0A7E6DHY6
names: Similarity
messages: Belongs to the potassium channel KCNE family.

89673:LOC118498160
gene id: 89673:LOC118498160
uniprot id: A0A7E6CYS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:VSIG1
gene id: 89673:VSIG1
uniprot id: A0A6J2MMT0
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114497897
gene id: 89673:LOC114497897
uniprot id: A0A7E6DSQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

89673:ANO1
gene id: 89673:ANO1
uniprot id: A0A7E6E2D5
uniprot id: A0A7E6E2X0
uniprot id: A0A7E6E2X3
uniprot id: A0A7E6E356
uniprot id: A0A7E6E358
uniprot id: A0A7E6E3U1
uniprot id: A0A7E6E3U5
uniprot id: A0A7E6E3U6
uniprot id: A0A7E6E3V3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:RPRD2
gene id: 89673:RPRD2
uniprot id: A0A6J2KSP6
uniprot id: A0A6J2KT97
uniprot id: A0A6J2KYP0
uniprot id: A0A7E6CXB1
uniprot id: A0A7E6CXT8
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

89673:LOC114490331
gene id: 89673:LOC114490331
uniprot id: A0A6J2L1E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114493163
gene id: 89673:LOC114493163
uniprot id: A0A6J2L7Q6
uniprot id: A0A7E6DQI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

89673:SFR1
gene id: 89673:SFR1
uniprot id: A0A6J2LQ35
uniprot id: A0A7E6DVA5
uniprot id: A0A7E6DVF0
uniprot id: A0A7E6DVX2
uniprot id: A0A7E6DW91
uniprot id: A0A7E6DWP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

89673:LOC114499023
gene id: 89673:LOC114499023
uniprot id: A0A6J2LXT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CHD6
gene id: 89673:CHD6
uniprot id: A0A6J2MSH0
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

89673:LOC114512149
gene id: 89673:LOC114512149
uniprot id: A0A7E6CWS5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114499057
gene id: 89673:LOC114499057
uniprot id: A0A6J2LUV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:BDKRB1
gene id: 89673:BDKRB1
uniprot id: A0A6J2L984
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

89673:LPAR5
gene id: 89673:LPAR5
uniprot id: A0A7E6D2P0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:SPIN1
gene id: 89673:SPIN1
uniprot id: A0A6J2N5Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

89673:ECHS1
gene id: 89673:ECHS1
uniprot id: A0A6J2LN42
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

89673:FAHD1
gene id: 89673:FAHD1
uniprot id: A0A6J2LVT3
names: Similarity
messages: Belongs to the FAH family.

89673:LOC114504751
gene id: 89673:LOC114504751
uniprot id: A0A6J2MGG4
names: Similarity
messages: Belongs to the BEX family.

89673:LOC114507789
gene id: 89673:LOC114507789
uniprot id: A0A6J2MQ18
uniprot id: A0A7E6CIS6
uniprot id: A0A7E6CJ51
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:IDH3A
gene id: 89673:IDH3A
uniprot id: A0A6J2KVW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

89673:LOC114511671
gene id: 89673:LOC114511671
uniprot id: A0A7E6CQY5
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114488894
gene id: 89673:LOC114488894
uniprot id: A0A6J2KVB6
uniprot id: A0A7E6CXH7
uniprot id: A0A7E6CY02
names: Similarity
messages: Belongs to the arrestin family.

89673:APOD
gene id: 89673:APOD
uniprot id: A0A6J2L1J9
uniprot id: A0A6J2L3F4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Homodimer.
messages: Secreted

89673:SLC9A4
gene id: 89673:SLC9A4
uniprot id: A0A7E6DZD4
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

89673:BAIAP2
gene id: 89673:BAIAP2
uniprot id: A0A6J2M8B8
uniprot id: A0A7E6EFF0
uniprot id: A0A7E6EFR6
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

89673:DOC2B
gene id: 89673:DOC2B
uniprot id: A0A6J2MEQ5
uniprot id: A0A7E6ECX3
uniprot id: A0A7E6EDQ6
names: Subcellular Location Annotation
messages: Membrane

89673:POLE
gene id: 89673:POLE
uniprot id: A0A6J2KVY8
uniprot id: A0A7E6CTK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

89673:B4GALT5
gene id: 89673:B4GALT5
uniprot id: A0A6J2MPR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

89673:LOC114510000
gene id: 89673:LOC114510000
uniprot id: A0A6J2N2H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

89673:ACTR3
gene id: 89673:ACTR3
uniprot id: A0A6J2LEF7
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

89673:CALHM1
gene id: 89673:CALHM1
uniprot id: A0A6J2LPQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

89673:ADSL
gene id: 89673:ADSL
uniprot id: A0A6J2NG77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

89673:CLDN20
gene id: 89673:CLDN20
uniprot id: A0A6J2LEG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:UGGT2
gene id: 89673:UGGT2
uniprot id: A0A6J2MSE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

89673:GSDMB
gene id: 89673:GSDMB
uniprot id: A0A7E6EFE6
uniprot id: A0A7E6EH92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

89673:GABRR2
gene id: 89673:GABRR2
uniprot id: A0A6J2LFG0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:LOC114489381
gene id: 89673:LOC114489381
uniprot id: A0A6J2KWS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

89673:MKI67
gene id: 89673:MKI67
uniprot id: A0A7E6DX05
names: Subcellular Location Annotation
messages: Nucleus

89673:CALHM2
gene id: 89673:CALHM2
uniprot id: A0A6J2LK96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

89673:CDC5L
gene id: 89673:CDC5L
uniprot id: A0A6J2LB67
names: Similarity
messages: Belongs to the CEF1 family.

89673:ENAH
gene id: 89673:ENAH
uniprot id: A0A6J2N9P6
uniprot id: A0A7E6CYB1
uniprot id: A0A7E6CYF8
uniprot id: A0A7E6CYG2
uniprot id: A0A7E6CYR8
uniprot id: A0A7E6CZ85
uniprot id: A0A7E6D0Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

89673:ZCCHC8
gene id: 89673:ZCCHC8
uniprot id: A0A6J2MWE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

89673:DPM1
gene id: 89673:DPM1
uniprot id: A0A6J2MKC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex.

89673:PNRC2
gene id: 89673:PNRC2
uniprot id: A0A6J2LNJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNRC family. PNRC2 subfamily.
messages: Nucleus
messages: P-body

89673:EPHA1
gene id: 89673:EPHA1
uniprot id: A0A6J2MV40
names: Subcellular Location Annotation
messages: Membrane

89673:SLC39A3
gene id: 89673:SLC39A3
uniprot id: A0A6J2MC74
names: Subcellular Location Annotation
messages: Membrane

89673:NKX1-2
gene id: 89673:NKX1-2
uniprot id: A0A6J2LI87
names: Subcellular Location Annotation
messages: Nucleus

89673:GNA11
gene id: 89673:GNA11
uniprot id: A0A6J2M7H2
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

89673:C6H11orf68
gene id: 89673:C6H11orf68
uniprot id: A0A6J2M1A1
uniprot id: A0A6J2M4R2
names: Similarity
messages: Belongs to the UPF0696 family.

89673:GLYR1
gene id: 89673:GLYR1
uniprot id: A0A6J2NCY4
uniprot id: A0A6J2NCZ1
uniprot id: A0A7E6DBS8
uniprot id: A0A7E6DC20
uniprot id: A0A7E6DCF2
uniprot id: A0A7E6DD00
uniprot id: A0A7E6DDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Chromosome

89673:LOC114490925
gene id: 89673:LOC114490925
uniprot id: A0A6J2L586
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

89673:UBE2B
gene id: 89673:UBE2B
uniprot id: A0A6J2MU23
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:CACNA1G
gene id: 89673:CACNA1G
uniprot id: A0A6J2MCX4
uniprot id: A0A6J2MCY5
uniprot id: A0A6J2MF05
uniprot id: A0A6J2MF11
uniprot id: A0A6J2MF14
uniprot id: A0A6J2MF16
uniprot id: A0A6J2MF17
uniprot id: A0A6J2MF23
uniprot id: A0A6J2MI47
uniprot id: A0A6J2MI78
uniprot id: A0A6J2MI89
uniprot id: A0A6J2MIW7
uniprot id: A0A6J2MIX2
uniprot id: A0A6J2MIY2
uniprot id: A0A7E6EDG7
uniprot id: A0A7E6EDH4
uniprot id: A0A7E6EE25
uniprot id: A0A7E6EE31
uniprot id: A0A7E6EE86
uniprot id: A0A7E6EF17
uniprot id: A0A7E6EF22
uniprot id: A0A7E6EF93
uniprot id: A0A7E6EF95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

89673:YPEL3
gene id: 89673:YPEL3
uniprot id: A0A6J2N7U5
uniprot id: A0A7E6DCS7
names: Similarity
messages: Belongs to the yippee family.

89673:TUBE1
gene id: 89673:TUBE1
uniprot id: A0A6J2LG91
uniprot id: A0A7E6DNB9
names: Similarity
messages: Belongs to the tubulin family.

89673:LOC114500294
gene id: 89673:LOC114500294
uniprot id: A0A6J2LYD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:UPP1
gene id: 89673:UPP1
uniprot id: A0A6J2M3P2
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

89673:SLC9C1
gene id: 89673:SLC9C1
uniprot id: A0A6J2KYL3
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

89673:ZNF445
gene id: 89673:ZNF445
uniprot id: A0A6J2M3M6
uniprot id: A0A7E6E4Q0
names: Subcellular Location Annotation
messages: Nucleus

89673:MVK
gene id: 89673:MVK
uniprot id: A0A6J2N1A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm

89673:TOP3B
gene id: 89673:TOP3B
uniprot id: A0A6J2MVU3
uniprot id: A0A7E6CUQ6
uniprot id: A0A7E6CVI4
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

89673:CDK5R2
gene id: 89673:CDK5R2
uniprot id: A0A6J2LG53
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

89673:SYNE4
gene id: 89673:SYNE4
uniprot id: A0A7E6CPG5
uniprot id: A0A7E6CPH1
uniprot id: A0A7E6CPS5
uniprot id: A0A7E6CRY7
names: Similarity
messages: Belongs to the nesprin family.

89673:FA2H
gene id: 89673:FA2H
uniprot id: A0A6J2NJX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:MAP4
gene id: 89673:MAP4
uniprot id: A0A6J2M2I6
uniprot id: A0A6J2M407
uniprot id: A0A7E6E3Z9
uniprot id: A0A7E6E406
uniprot id: A0A7E6E409
uniprot id: A0A7E6E413
uniprot id: A0A7E6E4I8
uniprot id: A0A7E6E4J3
uniprot id: A0A7E6E4J9
uniprot id: A0A7E6E4K1
uniprot id: A0A7E6E4N3
uniprot id: A0A7E6E4N8
uniprot id: A0A7E6E4P4
uniprot id: A0A7E6E4Q1
uniprot id: A0A7E6E4Q5
uniprot id: A0A7E6E5H2
uniprot id: A0A7E6E5H8
uniprot id: A0A7E6E5I3
uniprot id: A0A7E6E5I7
uniprot id: A0A7E6E5M4
uniprot id: A0A7E6E5N3
uniprot id: A0A7E6E5N9
uniprot id: A0A7E6E5P5
names: Subcellular Location Annotation
messages: cytoskeleton

89673:GK5
gene id: 89673:GK5
uniprot id: A0A6J2KTS9
uniprot id: A0A7E6D4N9
uniprot id: A0A7E6D4S4
names: Similarity
messages: Belongs to the FGGY kinase family.

89673:IPO9
gene id: 89673:IPO9
uniprot id: A0A6J2N4Y8
uniprot id: A0A7E6CYC8
uniprot id: A0A7E6CYT2
names: Subcellular Location Annotation
messages: Cytoplasm

89673:TMPRSS13
gene id: 89673:TMPRSS13
uniprot id: A0A6J2LUE7
uniprot id: A0A7E6DYU7
uniprot id: A0A7E6DYX4
uniprot id: A0A7E6DZC1
uniprot id: A0A7E6DZT9
uniprot id: A0A7E6E069
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:IGFBP4
gene id: 89673:IGFBP4
uniprot id: A0A6J2MAB9
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:TTLL9
gene id: 89673:TTLL9
uniprot id: A0A6J2MR93
names: Similarity
messages: Belongs to the tubulin--tyrosine ligase family.

89673:NETO1
gene id: 89673:NETO1
uniprot id: A0A7E6CGG5
uniprot id: A0A7E6CGW0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:KAT6A
gene id: 89673:KAT6A
uniprot id: A0A6J2MRM6
uniprot id: A0A6J2MWG2
uniprot id: A0A7E6CKL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

89673:SLC8A1
gene id: 89673:SLC8A1
uniprot id: A0A6J2LT64
uniprot id: A0A6J2LT70
uniprot id: A0A6J2LW70
uniprot id: A0A7E6DX91
uniprot id: A0A7E6DX95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

89673:MRPL17
gene id: 89673:MRPL17
uniprot id: A0A6J2M019
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

89673:GALNT15
gene id: 89673:GALNT15
uniprot id: A0A6J2M7L5
uniprot id: A0A7E6E553
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC114499021
gene id: 89673:LOC114499021
uniprot id: A0A6J2LY84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC22A9
gene id: 89673:SLC22A9
uniprot id: A0A6J2M2G5
uniprot id: A0A6J2M4Y5
uniprot id: A0A7E6E2I0
uniprot id: A0A7E6E389
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114505744
gene id: 89673:LOC114505744
uniprot id: A0A7E6D266
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

89673:CCSER1
gene id: 89673:CCSER1
uniprot id: A0A6J2L692
uniprot id: A0A7E6DTS0
uniprot id: A0A7E6DU66
names: Similarity
messages: Belongs to the CCSER family.

89673:GLYATL2
gene id: 89673:GLYATL2
uniprot id: A0A6J2M1Q8
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

89673:KRT23
gene id: 89673:KRT23
uniprot id: A0A6J2M9S6
names: Similarity
messages: Belongs to the intermediate filament family.

89673:ADPRH
gene id: 89673:ADPRH
uniprot id: A0A6J2L401
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

89673:UBE2L6
gene id: 89673:UBE2L6
uniprot id: A0A6J2M082
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:INSM2
gene id: 89673:INSM2
uniprot id: A0A6J2L330
names: Subcellular Location Annotation
messages: Nucleus

89673:DNAJB14
gene id: 89673:DNAJB14
uniprot id: A0A6J2L875
names: Subcellular Location Annotation
messages: Membrane

89673:CLIC3
gene id: 89673:CLIC3
uniprot id: A0A6J2MMY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

89673:VIPR2
gene id: 89673:VIPR2
uniprot id: A0A6J2MQE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

89673:SESN3
gene id: 89673:SESN3
uniprot id: A0A6J2M1P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

89673:RHBDD1
gene id: 89673:RHBDD1
uniprot id: A0A6J2LHF7
names: Subcellular Location Annotation
messages: Membrane

89673:ACTB
gene id: 89673:ACTB
uniprot id: A0A6J2MYQ0
names: Similarity
messages: Belongs to the actin family.

89673:BTNL9
gene id: 89673:BTNL9
uniprot id: A0A7E6CSN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:OSBPL8
gene id: 89673:OSBPL8
uniprot id: A0A6J2KVQ6
uniprot id: A0A6J2KVR0
uniprot id: A0A6J2KXX1
uniprot id: A0A6J2KZK3
uniprot id: A0A7E6D5K0
uniprot id: A0A7E6D687
uniprot id: A0A7E6D693
names: Similarity
messages: Belongs to the OSBP family.

89673:DLAT
gene id: 89673:DLAT
uniprot id: A0A6J2LWG6
uniprot id: A0A7E6DZI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Mitochondrion matrix
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

89673:HOATZ
gene id: 89673:HOATZ
uniprot id: A0A7E6DZ40
names: Similarity
messages: Belongs to the HOATZ family.

89673:PPM1N
gene id: 89673:PPM1N
uniprot id: A0A7E6CP91
names: Similarity
messages: Belongs to the PP2C family.

89673:LOC114512659
gene id: 89673:LOC114512659
uniprot id: A0A7E6D1Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:ZSCAN29
gene id: 89673:ZSCAN29
uniprot id: A0A6J2L4V4
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

89673:HOXC4
gene id: 89673:HOXC4
uniprot id: A0A6J2NEV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:AK5
gene id: 89673:AK5
uniprot id: A0A6J2LQE8
uniprot id: A0A6J2LTG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family.
messages: Cytoplasm

89673:LOC114500954
gene id: 89673:LOC114500954
uniprot id: A0A6J2M0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114490191
gene id: 89673:LOC114490191
uniprot id: A0A6J2KZ59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RNF20
gene id: 89673:RNF20
uniprot id: A0A6J2LLQ4
uniprot id: A0A6J2LPF4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

89673:CBY2
gene id: 89673:CBY2
uniprot id: A0A6J2MRC1
names: Similarity
names: Subunit
messages: Belongs to the chibby family. SPERT subfamily.
messages: Homodimer. Binds to NEK1.

89673:LCN12
gene id: 89673:LCN12
uniprot id: A0A7E6DHA9
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

89673:FGF23
gene id: 89673:FGF23
uniprot id: A0A6J2N9E2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:DAG1
gene id: 89673:DAG1
uniprot id: A0A6J2M1M7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

89673:OLFM3
gene id: 89673:OLFM3
uniprot id: A0A6J2KU10
uniprot id: A0A6J2KZD4
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

89673:LOC114511294
gene id: 89673:LOC114511294
uniprot id: A0A7E6CNY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

89673:KCNA1
gene id: 89673:KCNA1
uniprot id: A0A6J2N640
names: Subcellular Location Annotation
messages: Membrane

89673:LCN6
gene id: 89673:LCN6
uniprot id: A0A7E6D9S0
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

89673:RYR3
gene id: 89673:RYR3
uniprot id: A0A7E6E6Q4
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

89673:CFAP157
gene id: 89673:CFAP157
uniprot id: A0A6J2MNI4
names: Similarity
messages: Belongs to the CFAP157 family.

89673:LOC114506740
gene id: 89673:LOC114506740
uniprot id: A0A7E6CGI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

89673:MARVELD1
gene id: 89673:MARVELD1
uniprot id: A0A6J2LQE3
names: Subcellular Location Annotation
messages: Membrane

89673:CSF1R
gene id: 89673:CSF1R
uniprot id: A0A6J2N0N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

89673:GLB1L2
gene id: 89673:GLB1L2
uniprot id: A0A6J2N1W7
uniprot id: A0A7E6CUZ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

89673:LNPK
gene id: 89673:LNPK
uniprot id: A0A6J2LHM8
uniprot id: A0A7E6DJB0
uniprot id: A0A7E6DJJ1
uniprot id: A0A7E6DJQ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

89673:ATP7B
gene id: 89673:ATP7B
uniprot id: A0A6J2MS23
uniprot id: A0A7E6CJM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

89673:PPP1CB
gene id: 89673:PPP1CB
uniprot id: A0A6J2M2Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

89673:AMIGO1
gene id: 89673:AMIGO1
uniprot id: A0A6J2KZX2
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

89673:SLC27A1
gene id: 89673:SLC27A1
uniprot id: A0A6J2M8N5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:BRMS1L
gene id: 89673:BRMS1L
uniprot id: A0A6J2L6C6
uniprot id: A0A6J2LA40
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114500523
gene id: 89673:LOC114500523
uniprot id: A0A6J2LZ60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114490248
gene id: 89673:LOC114490248
uniprot id: A0A6J2KZE1
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:NTRK1
gene id: 89673:NTRK1
uniprot id: A0A6J2KVW3
uniprot id: A0A7E6CVS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

89673:ST3GAL1
gene id: 89673:ST3GAL1
uniprot id: A0A6J2ND55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:LOC118499647
gene id: 89673:LOC118499647
uniprot id: A0A7E6DEI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ANHX
gene id: 89673:ANHX
uniprot id: A0A7E6CVC9
names: Subcellular Location Annotation
messages: Nucleus

89673:RTRAF
gene id: 89673:RTRAF
uniprot id: A0A6J2L2F0
names: Similarity
messages: Belongs to the RTRAF family.

89673:UTS2R
gene id: 89673:UTS2R
uniprot id: A0A6J2MDB4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

89673:PRSS12
gene id: 89673:PRSS12
uniprot id: A0A6J2MGC6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
messages: Secreted

89673:DPM2
gene id: 89673:DPM2
uniprot id: A0A6J2MCQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

89673:DLGAP4
gene id: 89673:DLGAP4
uniprot id: A0A6J2MHH2
uniprot id: A0A6J2MNS2
uniprot id: A0A7E6CFD3
uniprot id: A0A7E6CFZ5
names: Similarity
messages: Belongs to the SAPAP family.

89673:NFU1
gene id: 89673:NFU1
uniprot id: A0A6J2LVM9
uniprot id: A0A6J2LWL7
uniprot id: A0A6J2LZJ8
uniprot id: A0A7E6DXS6
uniprot id: A0A7E6DXW6
uniprot id: A0A7E6DY98
uniprot id: A0A7E6DYA5
uniprot id: A0A7E6DZ53
names: Similarity
messages: Belongs to the NifU family.

89673:ALMS1
gene id: 89673:ALMS1
uniprot id: A0A7E6DXT5
uniprot id: A0A7E6DXU0
uniprot id: A0A7E6DXX9
uniprot id: A0A7E6DXY5
uniprot id: A0A7E6DYA9
uniprot id: A0A7E6DYB5
uniprot id: A0A7E6DYS7
uniprot id: A0A7E6DYT4
uniprot id: A0A7E6DZ63
uniprot id: A0A7E6DZ71
names: Subcellular Location Annotation
messages: centrosome

89673:TEX10
gene id: 89673:TEX10
uniprot id: A0A6J2L219
uniprot id: A0A7E6DFP9
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

89673:PIEZO1
gene id: 89673:PIEZO1
uniprot id: A0A7E6CN20
uniprot id: A0A7E6CN24
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:SMIM24
gene id: 89673:SMIM24
uniprot id: A0A7E6EF57
uniprot id: A0A7E6EGX9
names: Subcellular Location Annotation
messages: Membrane

89673:CA8
gene id: 89673:CA8
uniprot id: A0A6J2ND24
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

89673:SNRPD3
gene id: 89673:SNRPD3
uniprot id: A0A6J2MW67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
messages: cytosol

89673:AMPD1
gene id: 89673:AMPD1
uniprot id: A0A6J2KU16
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

89673:KRT12
gene id: 89673:KRT12
uniprot id: A0A6J2ME78
names: Similarity
messages: Belongs to the intermediate filament family.

89673:LOC114503176
gene id: 89673:LOC114503176
uniprot id: A0A6J2M8V2
names: Function
names: Subcellular Location Annotation
messages: Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
messages: extracellular matrix

89673:GPR142
gene id: 89673:GPR142
uniprot id: A0A6J2MB18
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:LOC114505647
gene id: 89673:LOC114505647
uniprot id: A0A7E6D3B8
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:CTNNB1
gene id: 89673:CTNNB1
uniprot id: A0A6J2M667
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: adherens junction

89673:RAPSN
gene id: 89673:RAPSN
uniprot id: A0A6J2M313
uniprot id: A0A7E6E154
names: Similarity
messages: Belongs to the RAPsyn family.

89673:TSEN34
gene id: 89673:TSEN34
uniprot id: A0A6J2N0G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

89673:GGPS1
gene id: 89673:GGPS1
uniprot id: A0A6J2N547
uniprot id: A0A6J2N9Q7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

89673:LOC114507522
gene id: 89673:LOC114507522
uniprot id: A0A7E6CI62
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

89673:ARID5B
gene id: 89673:ARID5B
uniprot id: A0A6J2LMU4
uniprot id: A0A6J2LNK6
names: Similarity
messages: Belongs to the ARID5B family.

89673:PIK3R1
gene id: 89673:PIK3R1
uniprot id: A0A6J2M0P0
uniprot id: A0A6J2M2S7
uniprot id: A0A6J2M675
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

89673:LOC114509085
gene id: 89673:LOC114509085
uniprot id: A0A6J2MYR7
uniprot id: A0A7E6DH63
names: Similarity
messages: Belongs to the ficolin lectin family.

89673:COMTD1
gene id: 89673:COMTD1
uniprot id: A0A6J2LSG5
uniprot id: A0A7E6DUV3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

89673:CCNP
gene id: 89673:CCNP
uniprot id: A0A7E6CLL4
names: Similarity
messages: Belongs to the cyclin family.

89673:MYOZ3
gene id: 89673:MYOZ3
uniprot id: A0A7E6CSN6
names: Similarity
messages: Belongs to the myozenin family.

89673:TMEM132E
gene id: 89673:TMEM132E
uniprot id: A0A6J2MD84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

89673:SLITRK3
gene id: 89673:SLITRK3
uniprot id: A0A6J2L4L4
names: Similarity
messages: Belongs to the SLITRK family.

89673:MIF
gene id: 89673:MIF
uniprot id: A0A6J2MV69
names: Similarity
messages: Belongs to the MIF family.

89673:SYVN1
gene id: 89673:SYVN1
uniprot id: A0A6J2LZK6
uniprot id: A0A7E6E2M0
uniprot id: A0A7E6E2T5
uniprot id: A0A7E6E3I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRD1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:OIP5
gene id: 89673:OIP5
uniprot id: A0A6J2LBQ5
names: Function
names: Subcellular Location Annotation
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

89673:LOC114503647
gene id: 89673:LOC114503647
uniprot id: A0A6J2MFP4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NT5DC3
gene id: 89673:NT5DC3
uniprot id: A0A6J2NDP9
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

89673:HOXA7
gene id: 89673:HOXA7
uniprot id: A0A6J2MU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:GRM1
gene id: 89673:GRM1
uniprot id: A0A6J2LF88
uniprot id: A0A6J2LGI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

89673:PTGDS
gene id: 89673:PTGDS
uniprot id: A0A6J2MUF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Membrane
messages: Monomer.
messages: Nucleus membrane
messages: Rough endoplasmic reticulum
messages: perinuclear region

89673:FTMT
gene id: 89673:FTMT
uniprot id: A0A6J2L8H2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:SERP2
gene id: 89673:SERP2
uniprot id: A0A6J2MS64
uniprot id: A0A7E6CK02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

89673:SLC25A39
gene id: 89673:SLC25A39
uniprot id: A0A6J2M8C8
uniprot id: A0A6J2M8Y1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis.
messages: Mitochondrion inner membrane

89673:EXOC4
gene id: 89673:EXOC4
uniprot id: A0A6J2MTL3
uniprot id: A0A7E6CIX5
uniprot id: A0A7E6CJ02
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

89673:COPS8
gene id: 89673:COPS8
uniprot id: A0A6J2LJH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

89673:TMEM201
gene id: 89673:TMEM201
uniprot id: A0A6J2LMA5
uniprot id: A0A7E6DQE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

89673:HNRNPA2B1
gene id: 89673:HNRNPA2B1
uniprot id: A0A6J2MNU4
uniprot id: A0A6J2MNX6
uniprot id: A0A6J2MT87
uniprot id: A0A6J2MTE5
names: Subcellular Location Annotation
messages: Cytoplasmic granule
messages: extracellular exosome

89673:MCUB
gene id: 89673:MCUB
uniprot id: A0A6J2L592
uniprot id: A0A7E6DQU2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

89673:LOC114498897
gene id: 89673:LOC114498897
uniprot id: A0A6J2LTQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:FAR1
gene id: 89673:FAR1
uniprot id: A0A6J2M0H3
uniprot id: A0A7E6E0D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

89673:TBC1D23
gene id: 89673:TBC1D23
uniprot id: A0A6J2L0E8
uniprot id: A0A6J2L2E0
uniprot id: A0A7E6D3U2
uniprot id: A0A7E6D6I1
names: Subcellular Location Annotation
messages: trans-Golgi network

89673:CLIC5
gene id: 89673:CLIC5
uniprot id: A0A6J2LFG8
uniprot id: A0A6J2LIY0
uniprot id: A0A7E6DM51
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

89673:GTF2H5
gene id: 89673:GTF2H5
uniprot id: A0A6J2LBY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

89673:TNFSF8
gene id: 89673:TNFSF8
uniprot id: A0A6J2M6T5
names: Similarity
messages: Belongs to the tumor necrosis factor family.

89673:ELL
gene id: 89673:ELL
uniprot id: A0A7E6EC40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

89673:FAM174A
gene id: 89673:FAM174A
uniprot id: A0A6J2M3Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

89673:LOC114503693
gene id: 89673:LOC114503693
uniprot id: A0A7E6EH57
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PDE3A
gene id: 89673:PDE3A
uniprot id: A0A7E6D7D6
uniprot id: A0A7E6D7H4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:IRX1
gene id: 89673:IRX1
uniprot id: A0A6J2N3Z4
uniprot id: A0A7E6DAE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

89673:PIK3R3
gene id: 89673:PIK3R3
uniprot id: A0A6J2LJQ1
uniprot id: A0A7E6DSY4
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

89673:POU2F1
gene id: 89673:POU2F1
uniprot id: A0A6J2N955
uniprot id: A0A7E6CVD0
uniprot id: A0A7E6CVT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus
messages: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.

89673:MEGF8
gene id: 89673:MEGF8
uniprot id: A0A7E6CP14
uniprot id: A0A7E6CP84
uniprot id: A0A7E6CPA3
uniprot id: A0A7E6CRG9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:CACTIN
gene id: 89673:CACTIN
uniprot id: A0A6J2MAD3
names: Similarity
messages: Belongs to the CACTIN family.

89673:MKNK2
gene id: 89673:MKNK2
uniprot id: A0A6J2MAG9
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:USP45
gene id: 89673:USP45
uniprot id: A0A6J2LIE9
uniprot id: A0A6J2LJ99
uniprot id: A0A7E6DMN9
uniprot id: A0A7E6DN77
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

89673:ADAM19
gene id: 89673:ADAM19
uniprot id: A0A6J2MVP0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114497960
gene id: 89673:LOC114497960
uniprot id: A0A6J2LV09
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SEMA3E
gene id: 89673:SEMA3E
uniprot id: A0A6J2MUM4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114499681
gene id: 89673:LOC114499681
uniprot id: A0A6J2M0V3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:MCTS1
gene id: 89673:MCTS1
uniprot id: A0A6J2MI14
uniprot id: A0A7E6D151
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

89673:ROCK2
gene id: 89673:ROCK2
uniprot id: A0A7E6DWE6
uniprot id: A0A7E6DWK2
uniprot id: A0A7E6DXD7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
messages: centrosome

89673:LOC114491050
gene id: 89673:LOC114491050
uniprot id: A0A6J2L4B0
uniprot id: A0A7E6D3Q9
uniprot id: A0A7E6D4F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CMTM3
gene id: 89673:CMTM3
uniprot id: A0A6J2KQJ3
names: Subcellular Location Annotation
messages: Membrane

89673:ANAPC13
gene id: 89673:ANAPC13
uniprot id: A0A6J2M7E1
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

89673:AP3B1
gene id: 89673:AP3B1
uniprot id: A0A6J2N5M4
uniprot id: A0A7E6DAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

89673:RPL18A
gene id: 89673:RPL18A
uniprot id: A0A6J2MB00
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

89673:PTPRZ1
gene id: 89673:PTPRZ1
uniprot id: A0A6J2MMG8
uniprot id: A0A6J2MPE0
uniprot id: A0A6J2MTQ2
uniprot id: A0A6J2MTY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

89673:NPC2
gene id: 89673:NPC2
uniprot id: A0A6J2L4C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

89673:LOC114504006
gene id: 89673:LOC114504006
uniprot id: A0A6J2MBF0
uniprot id: A0A6J2MDR2
uniprot id: A0A7E6EG66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

89673:FAM3A
gene id: 89673:FAM3A
uniprot id: A0A6J2MHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

89673:RPS6
gene id: 89673:RPS6
uniprot id: A0A6J2MIN7
uniprot id: A0A6J2MMR5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

89673:DUSP3
gene id: 89673:DUSP3
uniprot id: A0A6J2MDU6
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

89673:RYR2
gene id: 89673:RYR2
uniprot id: A0A7E6D0M9
names: Subcellular Location Annotation
messages: Sarcoplasmic reticulum membrane

89673:RHBG
gene id: 89673:RHBG
uniprot id: A0A6J2KU25
uniprot id: A0A7E6CVU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

89673:PARD3B
gene id: 89673:PARD3B
uniprot id: A0A6J2LII3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

89673:SLC2A5
gene id: 89673:SLC2A5
uniprot id: A0A6J2LMJ9
uniprot id: A0A7E6DPR0
uniprot id: A0A7E6DQD5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Membrane
messages: sarcolemma

89673:MFF
gene id: 89673:MFF
uniprot id: A0A6J2LCR3
uniprot id: A0A6J2LHM3
uniprot id: A0A6J2LIK0
uniprot id: A0A7E6DHX2
uniprot id: A0A7E6DHX6
uniprot id: A0A7E6DI06
uniprot id: A0A7E6DI37
uniprot id: A0A7E6DI41
uniprot id: A0A7E6DI56
uniprot id: A0A7E6DI90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.
messages: synaptic vesicle

89673:CKM
gene id: 89673:CKM
uniprot id: A0A6J2N6H0
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

89673:AURKB
gene id: 89673:AURKB
uniprot id: A0A6J2NJS2
uniprot id: A0A7E6EBB0
uniprot id: A0A7E6EC44
uniprot id: A0A7E6ED76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centromere

89673:DCAF10
gene id: 89673:DCAF10
uniprot id: A0A6J2MQG5
names: Function
names: Similarity
messages: Belongs to the WD repeat DCAF10 family.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

89673:CFI
gene id: 89673:CFI
uniprot id: A0A7E6DQ07
uniprot id: A0A7E6DQM0
uniprot id: A0A7E6DR41
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RPS6KA2
gene id: 89673:RPS6KA2
uniprot id: A0A6J2KYU8
uniprot id: A0A6J2L2G3
uniprot id: A0A7E6DPK7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

89673:NFKB2
gene id: 89673:NFKB2
uniprot id: A0A6J2LL24
uniprot id: A0A6J2LNP4
uniprot id: A0A7E6DVA6
uniprot id: A0A7E6DVR4
uniprot id: A0A7E6DWJ4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:LOC114503484
gene id: 89673:LOC114503484
uniprot id: A0A6J2MC44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CRK
gene id: 89673:CRK
uniprot id: A0A6J2M6C4
names: Similarity
messages: Belongs to the CRK family.

89673:OGFRL1
gene id: 89673:OGFRL1
uniprot id: A0A6J2LH19
uniprot id: A0A7E6DMY7
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

89673:MICAL3
gene id: 89673:MICAL3
uniprot id: A0A7E6CJG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Nucleus
messages: cytoskeleton

89673:EFNB1
gene id: 89673:EFNB1
uniprot id: A0A6J2MJZ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:MAPT
gene id: 89673:MAPT
uniprot id: A0A6J2M8P9
uniprot id: A0A6J2MAE1
uniprot id: A0A6J2MAT5
uniprot id: A0A6J2MDH1
uniprot id: A0A7E6ECZ7
uniprot id: A0A7E6ED01
uniprot id: A0A7E6ED06
uniprot id: A0A7E6EDJ8
uniprot id: A0A7E6EDK8
uniprot id: A0A7E6EDP3
uniprot id: A0A7E6EDP8
uniprot id: A0A7E6EDQ3
uniprot id: A0A7E6EEI0
uniprot id: A0A7E6EEI5
uniprot id: A0A7E6EEJ0
uniprot id: A0A7E6EER4
uniprot id: A0A7E6EES1
uniprot id: A0A7E6EES6
names: Subcellular Location Annotation
messages: Membrane
messages: axon
messages: cytoskeleton
messages: cytosol

89673:MB21D2
gene id: 89673:MB21D2
uniprot id: A0A6J2L1B0
uniprot id: A0A6J2L346
names: Similarity
messages: Belongs to the mab-21 family.

89673:ABCC6
gene id: 89673:ABCC6
uniprot id: A0A6J2L164
uniprot id: A0A7E6DBU7
uniprot id: A0A7E6DDJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

89673:CCL24
gene id: 89673:CCL24
uniprot id: A0A6J2LXX6
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

89673:EGR1
gene id: 89673:EGR1
uniprot id: A0A6J2MXE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

89673:SEC24D
gene id: 89673:SEC24D
uniprot id: A0A6J2MA67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

89673:SUPT3H
gene id: 89673:SUPT3H
uniprot id: A0A7E6DLR7
uniprot id: A0A7E6DM91
names: Subcellular Location Annotation
messages: Nucleus

89673:SOD1
gene id: 89673:SOD1
uniprot id: A0A6J2L0D1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

89673:GADD45GIP1
gene id: 89673:GADD45GIP1
uniprot id: A0A6J2MCQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
messages: Belongs to the mitochondrion-specific ribosomal protein mL64 family.
messages: Mitochondrion
messages: Nucleus

89673:NDUFAF3
gene id: 89673:NDUFAF3
uniprot id: A0A6J2M7L0
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

89673:JUNB
gene id: 89673:JUNB
uniprot id: A0A6J2MDS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

89673:LOC114499025
gene id: 89673:LOC114499025
uniprot id: A0A6J2LSQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ITGAX
gene id: 89673:ITGAX
uniprot id: A0A7E6D9N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:PRMT7
gene id: 89673:PRMT7
uniprot id: A0A6J2KQN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

89673:LOC114494221
gene id: 89673:LOC114494221
uniprot id: A0A6J2LBX2
uniprot id: A0A7E6DJR2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SERPINE2
gene id: 89673:SERPINE2
uniprot id: A0A6J2LEC5
names: Similarity
messages: Belongs to the serpin family.

89673:HHIPL2
gene id: 89673:HHIPL2
uniprot id: A0A6J2NB93
names: Similarity
messages: Belongs to the HHIP family.

89673:MMP27
gene id: 89673:MMP27
uniprot id: A0A6J2LZM5
names: Similarity
messages: Belongs to the peptidase M10A family.

89673:MOGS
gene id: 89673:MOGS
uniprot id: A0A6J2LWU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

89673:RBM17
gene id: 89673:RBM17
uniprot id: A0A6J2L7M5
uniprot id: A0A7E6DN25
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

89673:LOC114489892
gene id: 89673:LOC114489892
uniprot id: A0A6J2KWG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

89673:DDX50
gene id: 89673:DDX50
uniprot id: A0A6J2LI88
uniprot id: A0A6J2LJJ5
uniprot id: A0A7E6DUB9
uniprot id: A0A7E6DVI1
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

89673:LOC114500735
gene id: 89673:LOC114500735
uniprot id: A0A6J2M1Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MAGI3
gene id: 89673:MAGI3
uniprot id: A0A6J2KXZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

89673:LOC114510576
gene id: 89673:LOC114510576
uniprot id: A0A7E6CN14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:SLC6A1
gene id: 89673:SLC6A1
uniprot id: A0A6J2M629
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

89673:SLC8A3
gene id: 89673:SLC8A3
uniprot id: A0A6J2L8N5
uniprot id: A0A6J2L8P0
uniprot id: A0A6J2LAD2
uniprot id: A0A6J2LEB2
uniprot id: A0A7E6CKF6
uniprot id: A0A7E6CKG0
uniprot id: A0A7E6CKJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

89673:TENM2
gene id: 89673:TENM2
uniprot id: A0A6J2MWM7
uniprot id: A0A7E6CT95
uniprot id: A0A7E6CTS0
uniprot id: A0A7E6CU14
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:HS6ST3
gene id: 89673:HS6ST3
uniprot id: A0A6J2MXK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

89673:GLRX
gene id: 89673:GLRX
uniprot id: A0A6J2M946
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

89673:SFT2D3
gene id: 89673:SFT2D3
uniprot id: A0A7E6DL62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

89673:RAPGEF2
gene id: 89673:RAPGEF2
uniprot id: A0A6J2MDF3
uniprot id: A0A6J2MDF5
uniprot id: A0A6J2MGD2
uniprot id: A0A6J2MH62
uniprot id: A0A7E6E887
uniprot id: A0A7E6E893
uniprot id: A0A7E6E906
uniprot id: A0A7E6E909
uniprot id: A0A7E6E972
uniprot id: A0A7E6E9U1
uniprot id: A0A7E6E9U5
uniprot id: A0A7E6EA71
uniprot id: A0A7E6EA80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAPGEF2 family.
messages: Cell junction
messages: Endosome
messages: Late endosome
messages: perinuclear region

89673:SNRPD1
gene id: 89673:SNRPD1
uniprot id: A0A6J2MK42
uniprot id: A0A7E6CDT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP core protein family.
messages: Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Most spliceosomal snRNPs contain a common set of Sm proteins, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. Component of the U1 snRNP. The U1 snRNP is composed of the U1 snRNA and the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG, and at least three U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39, plus LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Part of the SMN-Sm complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8, STRAP/UNRIP and the Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG; catalyzes core snRNPs assembly. Forms a 6S pICln-Sm complex composed of CLNS1A/pICln, SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG; ring-like structure where CLNS1A/pICln mimics additional Sm proteins and which is unable to assemble into the core snRNP.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.
messages: cytosol

89673:NLGN1
gene id: 89673:NLGN1
uniprot id: A0A6J2KYW8
uniprot id: A0A6J2KZH5
uniprot id: A0A6J2L156
uniprot id: A0A7E6D3J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

89673:LOC114492776
gene id: 89673:LOC114492776
uniprot id: A0A6J2L5X7
uniprot id: A0A6J2L6P1
uniprot id: A0A6J2L819
uniprot id: A0A6J2L821
uniprot id: A0A6J2L826
uniprot id: A0A6J2LAP4
uniprot id: A0A6J2LC08
uniprot id: A0A7E6DVH9
uniprot id: A0A7E6DVK1
uniprot id: A0A7E6DVK8
uniprot id: A0A7E6DVQ5
uniprot id: A0A7E6DVU6
uniprot id: A0A7E6DWD8
uniprot id: A0A7E6DWI3
uniprot id: A0A7E6DWL6
uniprot id: A0A7E6DWZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114496355
gene id: 89673:LOC114496355
uniprot id: A0A6J2LNU8
uniprot id: A0A7E6DRQ4
uniprot id: A0A7E6DRS5
uniprot id: A0A7E6DSD9
uniprot id: A0A7E6DSW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

89673:SLC30A5
gene id: 89673:SLC30A5
uniprot id: A0A6J2L7S3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: trans-Golgi network membrane

89673:LOC118499104
gene id: 89673:LOC118499104
uniprot id: A0A7E6D737
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

89673:LOC114499113
gene id: 89673:LOC114499113
uniprot id: A0A6J2LU51
names: Subcellular Location Annotation
messages: Membrane

89673:CCR2
gene id: 89673:CCR2
uniprot id: A0A6J2M752
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:LOC114504959
gene id: 89673:LOC114504959
uniprot id: A0A7E6CZV9
names: Similarity
names: Subunit
messages: Belongs to the uridine kinase family.
messages: Homotetramer.

89673:RBP4
gene id: 89673:RBP4
uniprot id: A0A6J2LQ68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Interacts with TTR.
messages: Retinol-binding protein that mediates retinol transport in blood plasma.
messages: Secreted

89673:LOC114505981
gene id: 89673:LOC114505981
uniprot id: A0A7E6CGJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

89673:LOC114500598
gene id: 89673:LOC114500598
uniprot id: A0A6J2M4G0
names: Similarity
messages: Belongs to the nucleoplasmin family.

89673:LOC114490273
gene id: 89673:LOC114490273
uniprot id: A0A6J2L306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

89673:ACAD11
gene id: 89673:ACAD11
uniprot id: A0A7E6E5D8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

89673:TMBIM6
gene id: 89673:TMBIM6
uniprot id: A0A6J2N7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

89673:PAPSS2
gene id: 89673:PAPSS2
uniprot id: A0A7E6DVZ1
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

89673:LOC114510257
gene id: 89673:LOC114510257
uniprot id: A0A7E6CRP7
names: Similarity
messages: Belongs to the peptidase C12 family.

89673:SLC29A4
gene id: 89673:SLC29A4
uniprot id: A0A7E6CS71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

89673:SNUPN
gene id: 89673:SNUPN
uniprot id: A0A6J2LC73
uniprot id: A0A7E6DW83
uniprot id: A0A7E6DXN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

89673:P3H2
gene id: 89673:P3H2
uniprot id: A0A6J2KZZ2
names: Similarity
messages: Belongs to the leprecan family.

89673:LRRC8A
gene id: 89673:LRRC8A
uniprot id: A0A6J2LEL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

89673:LOC114507854
gene id: 89673:LOC114507854
uniprot id: A0A6J2MNB1
uniprot id: A0A7E6CIM6
uniprot id: A0A7E6CJ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

89673:GNS
gene id: 89673:GNS
uniprot id: A0A6J2N8V5
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

89673:RAD23B
gene id: 89673:RAD23B
uniprot id: A0A6J2LLE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

89673:KXD1
gene id: 89673:KXD1
uniprot id: A0A6J2M7X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Lysosome membrane

89673:EBF1
gene id: 89673:EBF1
uniprot id: A0A6J2MSH9
uniprot id: A0A6J2MU62
uniprot id: A0A6J2MU63
uniprot id: A0A6J2MYR2
uniprot id: A0A6J2MZ77
uniprot id: A0A7E6CTF7
uniprot id: A0A7E6CTF9
uniprot id: A0A7E6CW93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

89673:PARP8
gene id: 89673:PARP8
uniprot id: A0A6J2LQD1
names: Similarity
messages: Belongs to the ARTD/PARP family.

89673:LOC114502021
gene id: 89673:LOC114502021
uniprot id: A0A7E6E5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:HEXD
gene id: 89673:HEXD
uniprot id: A0A6J2M7N5
uniprot id: A0A7E6EF16
uniprot id: A0A7E6EGM9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

89673:CHD2
gene id: 89673:CHD2
uniprot id: A0A6J2KY27
names: Subcellular Location Annotation
messages: Nucleus

89673:OTOG
gene id: 89673:OTOG
uniprot id: A0A7E6E2V0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SOGA1
gene id: 89673:SOGA1
uniprot id: A0A6J2MPB9
uniprot id: A0A7E6CFD8
uniprot id: A0A7E6CG00
names: Similarity
messages: Belongs to the SOGA family.

89673:EHD4
gene id: 89673:EHD4
uniprot id: A0A6J2LBB6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

89673:TET2
gene id: 89673:TET2
uniprot id: A0A7E6DR02
uniprot id: A0A7E6DRV5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

89673:LOC114496168
gene id: 89673:LOC114496168
uniprot id: A0A7E6DEQ7
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

89673:LOC114500330
gene id: 89673:LOC114500330
uniprot id: A0A6J2LYI8
uniprot id: A0A7E6DCM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

89673:CDK2AP1
gene id: 89673:CDK2AP1
uniprot id: A0A6J2MWE2
uniprot id: A0A7E6CUP5
names: Similarity
messages: Belongs to the CDK2AP family.

89673:LOC114512914
gene id: 89673:LOC114512914
uniprot id: A0A6J2N7G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

89673:AGXT
gene id: 89673:AGXT
uniprot id: A0A6J2LI59
uniprot id: A0A7E6DHS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Peroxisome

89673:FGF3
gene id: 89673:FGF3
uniprot id: A0A6J2LV52
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:LOC114503777
gene id: 89673:LOC114503777
uniprot id: A0A6J2MD13
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MRPL1
gene id: 89673:MRPL1
uniprot id: A0A6J2L5Z8
names: Subcellular Location Annotation
messages: Mitochondrion

89673:HSPA4
gene id: 89673:HSPA4
uniprot id: A0A6J2MZE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.

89673:LOC114512257
gene id: 89673:LOC114512257
uniprot id: A0A6J2N506
names: Similarity
messages: Belongs to the NUT family.

89673:CCDC90B
gene id: 89673:CCDC90B
uniprot id: A0A6J2LZN7
uniprot id: A0A7E6DZJ7
uniprot id: A0A7E6DZK5
uniprot id: A0A7E6E010
uniprot id: A0A7E6E0J2
uniprot id: A0A7E6E0S2
names: Similarity
messages: Belongs to the CCDC90 family.

89673:LOC114490603
gene id: 89673:LOC114490603
uniprot id: A0A6J2L470
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

89673:SMPD2
gene id: 89673:SMPD2
uniprot id: A0A7E6DMT5
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

89673:MS4A15
gene id: 89673:MS4A15
uniprot id: A0A6J2M1X7
names: Similarity
messages: Belongs to the MS4A family.

89673:LOC114501816
gene id: 89673:LOC114501816
uniprot id: A0A7E6CHF7
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

89673:LOC114507340
gene id: 89673:LOC114507340
uniprot id: A0A6J2MNG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

89673:LOC118499356
gene id: 89673:LOC118499356
uniprot id: A0A7E6D9E5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.

89673:LOC114506724
gene id: 89673:LOC114506724
uniprot id: A0A6J2MQW7
names: Similarity
messages: Belongs to the cytochrome b5 family.

89673:EHF
gene id: 89673:EHF
uniprot id: A0A6J2M5I6
uniprot id: A0A7E6E0S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:LOC114489538
gene id: 89673:LOC114489538
uniprot id: A0A6J2L148
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:NOP16
gene id: 89673:NOP16
uniprot id: A0A6J2MUS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: nucleolus

89673:OTUB2
gene id: 89673:OTUB2
uniprot id: A0A6J2L5G6
names: Similarity
messages: Belongs to the peptidase C65 family.

89673:STXBP3
gene id: 89673:STXBP3
uniprot id: A0A6J2KXD5
uniprot id: A0A7E6CXW8
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

89673:HEG1
gene id: 89673:HEG1
uniprot id: A0A7E6D4E3
uniprot id: A0A7E6D4H0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114506863
gene id: 89673:LOC114506863
uniprot id: A0A7E6CGC2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

89673:PDIA4
gene id: 89673:PDIA4
uniprot id: A0A6J2MSU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

89673:QPCT
gene id: 89673:QPCT
uniprot id: A0A6J2M287
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

89673:LOC114491044
gene id: 89673:LOC114491044
uniprot id: A0A6J2L004
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NSUN7
gene id: 89673:NSUN7
uniprot id: A0A6J2L4R5
uniprot id: A0A7E6D9L8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:DUSP4
gene id: 89673:DUSP4
uniprot id: A0A6J2MT32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

89673:CCDC43
gene id: 89673:CCDC43
uniprot id: A0A6J2M8G4
uniprot id: A0A7E6EE90
names: Similarity
messages: Belongs to the CCDC43 family.

89673:ST6GALNAC6
gene id: 89673:ST6GALNAC6
uniprot id: A0A6J2LUR1
uniprot id: A0A7E6DGI1
uniprot id: A0A7E6DGL5
uniprot id: A0A7E6DGL9
uniprot id: A0A7E6DGQ9
uniprot id: A0A7E6DGS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:GCFC2
gene id: 89673:GCFC2
uniprot id: A0A7E6DY02
uniprot id: A0A7E6DYZ9
names: Similarity
messages: Belongs to the GCF family.

89673:LOC114513014
gene id: 89673:LOC114513014
uniprot id: A0A6J2N803
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

89673:AGTR1
gene id: 89673:AGTR1
uniprot id: A0A6J2KZN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

89673:TM4SF20
gene id: 89673:TM4SF20
uniprot id: A0A6J2LAW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

89673:LOC114501386
gene id: 89673:LOC114501386
uniprot id: A0A7E6E6R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cytoplasm
messages: Reversible hydration of carbon dioxide.

89673:LOC114494765
gene id: 89673:LOC114494765
uniprot id: A0A7E6DHG9
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

89673:UBR3
gene id: 89673:UBR3
uniprot id: A0A7E6DJG5
uniprot id: A0A7E6DJG6
uniprot id: A0A7E6DJH1
uniprot id: A0A7E6DJP7
uniprot id: A0A7E6DJP8
uniprot id: A0A7E6DJW0
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

89673:VPS13B
gene id: 89673:VPS13B
uniprot id: A0A6J2NBL0
uniprot id: A0A7E6E6H9
uniprot id: A0A7E6E7C8
uniprot id: A0A7E6E892
names: Similarity
messages: Belongs to the VPS13 family.

89673:SLC48A1
gene id: 89673:SLC48A1
uniprot id: A0A6J2N8I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.
messages: Lysosome membrane
messages: Membrane

89673:GARS1
gene id: 89673:GARS1
uniprot id: A0A6J2MP84
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

89673:LOC114490326
gene id: 89673:LOC114490326
uniprot id: A0A6J2L1D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114513465
gene id: 89673:LOC114513465
uniprot id: A0A6J2NEJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NDUFA5
gene id: 89673:NDUFA5
uniprot id: A0A6J2MP56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:NUS1
gene id: 89673:NUS1
uniprot id: A0A6J2LD28
names: Similarity
messages: Belongs to the UPP synthase family.

89673:LOC114489470
gene id: 89673:LOC114489470
uniprot id: A0A7E6CXZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:LOC114488950
gene id: 89673:LOC114488950
uniprot id: A0A7E6CYA6
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

89673:TIMM17B
gene id: 89673:TIMM17B
uniprot id: A0A6J2MGD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

89673:LOC114500032
gene id: 89673:LOC114500032
uniprot id: A0A6J2M2W9
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

89673:SLC13A1
gene id: 89673:SLC13A1
uniprot id: A0A6J2MSQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

89673:HSD17B4
gene id: 89673:HSD17B4
uniprot id: A0A6J2LHC9
names: Subcellular Location Annotation
messages: Peroxisome

89673:LOC114499081
gene id: 89673:LOC114499081
uniprot id: A0A6J2LSV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114511533
gene id: 89673:LOC114511533
uniprot id: A0A7E6CP93
names: Subcellular Location Annotation
messages: Membrane

89673:GNPAT
gene id: 89673:GNPAT
uniprot id: A0A6J2N561
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Peroxisome membrane

89673:MAP3K15
gene id: 89673:MAP3K15
uniprot id: A0A7E6D0E2
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

89673:RAD18
gene id: 89673:RAD18
uniprot id: A0A6J2M9F2
uniprot id: A0A7E6E583
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

89673:TOP3A
gene id: 89673:TOP3A
uniprot id: A0A6J2NDR9
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

89673:PHOSPHO1
gene id: 89673:PHOSPHO1
uniprot id: A0A6J2MDA2
uniprot id: A0A6J2MDV7
uniprot id: A0A7E6EDN1
uniprot id: A0A7E6EE89
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

89673:EPX
gene id: 89673:EPX
uniprot id: A0A7E6EDB3
uniprot id: A0A7E6EF34
names: Cofactor
messages: Binds 1 Ca(2+) ion per monomer.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group covalently per monomer.

89673:RTF2
gene id: 89673:RTF2
uniprot id: A0A6J2MLB3
uniprot id: A0A7E6CFX4
names: Similarity
names: Subunit
messages: Belongs to the rtf2 family.
messages: Interacts with DDI2; probably also interacts with DDI1.

89673:ZNF75A
gene id: 89673:ZNF75A
uniprot id: A0A6J2LEP0
uniprot id: A0A7E6D962
uniprot id: A0A7E6DA43
uniprot id: A0A7E6DC68
names: Subcellular Location Annotation
messages: Nucleus

89673:EZH1
gene id: 89673:EZH1
uniprot id: A0A6J2M7Z0
uniprot id: A0A6J2MCP7
uniprot id: A0A7E6EEK7
names: Subcellular Location Annotation
messages: Nucleus

89673:RBBP5
gene id: 89673:RBBP5
uniprot id: A0A6J2N213
uniprot id: A0A6J2N8E0
names: Subcellular Location Annotation
messages: Nucleus

89673:F3
gene id: 89673:F3
uniprot id: A0A6J2LP75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

89673:KIAA2013
gene id: 89673:KIAA2013
uniprot id: A0A6J2LNG4
names: Subcellular Location Annotation
messages: Membrane

89673:SRRD
gene id: 89673:SRRD
uniprot id: A0A6J2MUU8
names: Similarity
messages: Belongs to the SRR1 family.

89673:ORC5
gene id: 89673:ORC5
uniprot id: A0A6J2MPK3
uniprot id: A0A7E6CI32
uniprot id: A0A7E6CID1
uniprot id: A0A7E6CIH3
names: Subcellular Location Annotation
messages: Nucleus

89673:NKX1-1
gene id: 89673:NKX1-1
uniprot id: A0A6J2KVY7
names: Subcellular Location Annotation
messages: Nucleus

89673:PRORP
gene id: 89673:PRORP
uniprot id: A0A6J2LAQ7
names: Similarity
messages: Belongs to the PPR family. P subfamily.

89673:FER1L5
gene id: 89673:FER1L5
uniprot id: A0A7E6E2S2
names: Similarity
messages: Belongs to the ferlin family.

89673:PLA2G4E
gene id: 89673:PLA2G4E
uniprot id: A0A6J2LAL8
uniprot id: A0A7E6EAH7
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

89673:ARPC1A
gene id: 89673:ARPC1A
uniprot id: A0A6J2LP97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

89673:LOC114490028
gene id: 89673:LOC114490028
uniprot id: A0A6J2L087
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

89673:SPNS2
gene id: 89673:SPNS2
uniprot id: A0A6J2NJW1
uniprot id: A0A7E6ECT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

89673:ETV2
gene id: 89673:ETV2
uniprot id: A0A7E6CR51
uniprot id: A0A7E6CR72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:CDC73
gene id: 89673:CDC73
uniprot id: A0A6J2N5C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC73 family.
messages: Nucleus

89673:OAZ2
gene id: 89673:OAZ2
uniprot id: A0A6J2L4K5
names: Similarity
messages: Belongs to the ODC antizyme family.

89673:CPLX1
gene id: 89673:CPLX1
uniprot id: A0A6J2KWQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

89673:LOC114507696
gene id: 89673:LOC114507696
uniprot id: A0A7E6CJ47
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

89673:BDKRB2
gene id: 89673:BDKRB2
uniprot id: A0A6J2L7F9
uniprot id: A0A7E6CRP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

89673:LOC114510850
gene id: 89673:LOC114510850
uniprot id: A0A7E6CQH0
uniprot id: A0A7E6CT47
names: Similarity
messages: Belongs to the MHC class I family.

89673:RASGRP1
gene id: 89673:RASGRP1
uniprot id: A0A6J2L7L9
uniprot id: A0A7E6E8U5
names: Similarity
messages: Belongs to the RASGRP family.

89673:USP48
gene id: 89673:USP48
uniprot id: A0A6J2LIN2
uniprot id: A0A6J2LN38
uniprot id: A0A7E6DQB2
uniprot id: A0A7E6DR19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

89673:KLHL40
gene id: 89673:KLHL40
uniprot id: A0A6J2M8P8
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

89673:LYVE1
gene id: 89673:LYVE1
uniprot id: A0A6J2LWH0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114498896
gene id: 89673:LOC114498896
uniprot id: A0A6J2LXK1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114504721
gene id: 89673:LOC114504721
uniprot id: A0A6J2MG46
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

89673:LOC114500124
gene id: 89673:LOC114500124
uniprot id: A0A6J2LYV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:UTP3
gene id: 89673:UTP3
uniprot id: A0A6J2LCR2
names: Similarity
messages: Belongs to the SAS10 family.

89673:TRPV6
gene id: 89673:TRPV6
uniprot id: A0A6J2MTN0
uniprot id: A0A7E6CIV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:LOC114512289
gene id: 89673:LOC114512289
uniprot id: A0A6J2N3C6
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

89673:DMAC2L
gene id: 89673:DMAC2L
uniprot id: A0A7E6CFH5
uniprot id: A0A7E6CFL1
uniprot id: A0A7E6CFQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP synthase subunit s family.
messages: Homotetramer. Associates with ATP synthase.
messages: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
messages: Membrane
messages: Mitochondrion inner membrane

89673:DTX3L
gene id: 89673:DTX3L
uniprot id: A0A6J2KYF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

89673:LOC114507796
gene id: 89673:LOC114507796
uniprot id: A0A6J2MQ24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ETFDH
gene id: 89673:ETFDH
uniprot id: A0A6J2MCP4
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

89673:TBCD
gene id: 89673:TBCD
uniprot id: A0A7E6EFK3
names: Similarity
messages: Belongs to the TBCD family.

89673:UPP2
gene id: 89673:UPP2
uniprot id: A0A6J2LKT2
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

89673:SEMA4B
gene id: 89673:SEMA4B
uniprot id: A0A7E6CMR4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:NR0B2
gene id: 89673:NR0B2
uniprot id: A0A6J2LKW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

89673:KCNQ5
gene id: 89673:KCNQ5
uniprot id: A0A6J2LBH1
uniprot id: A0A6J2LCH7
uniprot id: A0A6J2LDL3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:DIPK2A
gene id: 89673:DIPK2A
uniprot id: A0A6J2KXW4
uniprot id: A0A7E6D3E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

89673:FAM124A
gene id: 89673:FAM124A
uniprot id: A0A6J2MY37
names: Similarity
messages: Belongs to the FAM124 family.

89673:NDUFB6
gene id: 89673:NDUFB6
uniprot id: A0A6J2MZI2
uniprot id: A0A6J2MZK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:DCST1
gene id: 89673:DCST1
uniprot id: A0A6J2KTP9
names: Subcellular Location Annotation
messages: Membrane

89673:ALDH16A1
gene id: 89673:ALDH16A1
uniprot id: A0A7E6CNH5
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Interacts with SPG21.

89673:ARG1
gene id: 89673:ARG1
uniprot id: A0A6J2LDL9
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

89673:SLC16A3
gene id: 89673:SLC16A3
uniprot id: A0A6J2MC97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

89673:NKX3-1
gene id: 89673:NKX3-1
uniprot id: A0A6J2MET0
names: Subcellular Location Annotation
messages: Nucleus

89673:BYSL
gene id: 89673:BYSL
uniprot id: A0A6J2LJT6
names: Similarity
messages: Belongs to the bystin family.

89673:LOC114508381
gene id: 89673:LOC114508381
uniprot id: A0A6J2MVV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:FYN
gene id: 89673:FYN
uniprot id: A0A7E6DMT8
uniprot id: A0A7E6DMU3
uniprot id: A0A7E6DNE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:LOC114514639
gene id: 89673:LOC114514639
uniprot id: A0A6J2NCY5
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

89673:LOC114489542
gene id: 89673:LOC114489542
uniprot id: A0A7E6CXM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

89673:ABHD16A
gene id: 89673:ABHD16A
uniprot id: A0A6J2LFP9
uniprot id: A0A6J2LJ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. ABHD16 family.
messages: Membrane

89673:EXT1
gene id: 89673:EXT1
uniprot id: A0A6J2NC09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Forms a homo/heterooligomeric complex with EXT2. Interacts with NDST1.
messages: Membrane
messages: cis-Golgi network membrane

89673:TBPL2
gene id: 89673:TBPL2
uniprot id: A0A6J2L3V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

89673:LOC118497509
gene id: 89673:LOC118497509
uniprot id: A0A7E6CM17
names: Subcellular Location Annotation
messages: Nucleus

89673:SPSB1
gene id: 89673:SPSB1
uniprot id: A0A6J2LKK4
names: Similarity
messages: Belongs to the SPSB family.

89673:CARNMT1
gene id: 89673:CARNMT1
uniprot id: A0A6J2MEA7
uniprot id: A0A7E6DF58
names: Similarity
messages: Belongs to the carnosine N-methyltransferase family.

89673:LOC114505498
gene id: 89673:LOC114505498
uniprot id: A0A6J2MMQ8
names: Subcellular Location Annotation
messages: Membrane

89673:BTG1
gene id: 89673:BTG1
uniprot id: A0A6J2N7C4
names: Function
names: Similarity
messages: Anti-proliferative protein.
messages: Belongs to the BTG family.

89673:SYNM
gene id: 89673:SYNM
uniprot id: A0A6J2KSK0
names: Similarity
messages: Belongs to the intermediate filament family.

89673:DGCR2
gene id: 89673:DGCR2
uniprot id: A0A6J2MTB6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SLC35C2
gene id: 89673:SLC35C2
uniprot id: A0A6J2MME2
names: Subcellular Location Annotation
messages: Membrane

89673:NT5DC2
gene id: 89673:NT5DC2
uniprot id: A0A6J2M198
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

89673:NRXN2
gene id: 89673:NRXN2
uniprot id: A0A6J2LU78
uniprot id: A0A6J2LVA4
uniprot id: A0A6J2LZS8
uniprot id: A0A7E6E1Z3
uniprot id: A0A7E6E1Z8
uniprot id: A0A7E6E202
uniprot id: A0A7E6E206
uniprot id: A0A7E6E209
uniprot id: A0A7E6E2H7
uniprot id: A0A7E6E2I2
uniprot id: A0A7E6E2I8
uniprot id: A0A7E6E2P2
uniprot id: A0A7E6E2P7
uniprot id: A0A7E6E2Q5
uniprot id: A0A7E6E2R0
uniprot id: A0A7E6E3D7
uniprot id: A0A7E6E3E3
uniprot id: A0A7E6E3E8
uniprot id: A0A7E6E3F0
uniprot id: A0A7E6E3F3
uniprot id: A0A7E6E3F6
uniprot id: A0A7E6E3G1
uniprot id: A0A7E6E3G6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:KCNK9
gene id: 89673:KCNK9
uniprot id: A0A6J2NHK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane
messages: pH-dependent, voltage-insensitive, background potassium channel protein.

89673:FAM210B
gene id: 89673:FAM210B
uniprot id: A0A6J2MSB1
names: Similarity
messages: Belongs to the FAM210 family.

89673:RSPO3
gene id: 89673:RSPO3
uniprot id: A0A6J2LEE2
names: Similarity
messages: Belongs to the R-spondin family.

89673:CRTC3
gene id: 89673:CRTC3
uniprot id: A0A6J2KRF9
uniprot id: A0A6J2KS13
uniprot id: A0A7E6CMW6
uniprot id: A0A7E6CMW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

89673:FAM83H
gene id: 89673:FAM83H
uniprot id: A0A6J2NHD8
uniprot id: A0A7E6E7A9
names: Similarity
messages: Belongs to the FAM83 family.

89673:CCDC130
gene id: 89673:CCDC130
uniprot id: A0A6J2MC55
names: Similarity
messages: Belongs to the CWC16 family.

89673:KCNJ1
gene id: 89673:KCNJ1
uniprot id: A0A6J2N250
uniprot id: A0A7E6CSK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

89673:NR1H3
gene id: 89673:NR1H3
uniprot id: A0A6J2M0P6
uniprot id: A0A7E6E1U3
uniprot id: A0A7E6E2K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

89673:LOC114496478
gene id: 89673:LOC114496478
uniprot id: A0A6J2LLA3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

89673:LCAT
gene id: 89673:LCAT
uniprot id: A0A6J2KSC1
uniprot id: A0A7E6CLX6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

89673:PUF60
gene id: 89673:PUF60
uniprot id: A0A6J2NAM1
uniprot id: A0A6J2NCA8
uniprot id: A0A6J2NCJ1
uniprot id: A0A6J2NCK5
uniprot id: A0A6J2NI28
uniprot id: A0A6J2NI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

89673:SORD
gene id: 89673:SORD
uniprot id: A0A6J2L7F1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 1 or 2 Zn(2+) ions per subunit.
messages: Homotetramer.
messages: Mitochondrion membrane
messages: Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is active with D-sorbitol (D-glucitol) leading to the C2-oxidized product D-fructose. Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility.
messages: flagellum

89673:IRX6
gene id: 89673:IRX6
uniprot id: A0A6J2KRM5
uniprot id: A0A7E6CLF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

89673:POMGNT1
gene id: 89673:POMGNT1
uniprot id: A0A6J2LP23
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

89673:LOC114488893
gene id: 89673:LOC114488893
uniprot id: A0A6J2KTA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SNX14
gene id: 89673:SNX14
uniprot id: A0A6J2L9L7
uniprot id: A0A6J2LA64
uniprot id: A0A6J2LBF2
uniprot id: A0A6J2LFA7
uniprot id: A0A7E6DMX7
uniprot id: A0A7E6DN95
names: Similarity
messages: Belongs to the sorting nexin family.

89673:KCNN3
gene id: 89673:KCNN3
uniprot id: A0A6J2KYA8
uniprot id: A0A7E6CX78
uniprot id: A0A7E6CXR0
uniprot id: A0A7E6CY43
uniprot id: A0A7E6CZX4
names: Subcellular Location Annotation
messages: Membrane

89673:LAMB3
gene id: 89673:LAMB3
uniprot id: A0A7E6CY18
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RSPO4
gene id: 89673:RSPO4
uniprot id: A0A6J2MNB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

89673:LOC114492560
gene id: 89673:LOC114492560
uniprot id: A0A7E6DCJ2
names: Similarity
messages: Belongs to the ubiquitin family. SUMO subfamily.

89673:CHGB
gene id: 89673:CHGB
uniprot id: A0A6J2MS67
uniprot id: A0A7E6CER4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

89673:OC90
gene id: 89673:OC90
uniprot id: A0A7E6E8B2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

89673:ABL2
gene id: 89673:ABL2
uniprot id: A0A6J2N201
uniprot id: A0A6J2N206
uniprot id: A0A6J2N3N9
uniprot id: A0A6J2N3P7
uniprot id: A0A6J2N3Q3
uniprot id: A0A6J2N8D1
uniprot id: A0A6J2N8D5
uniprot id: A0A7E6CVP7
uniprot id: A0A7E6CVU5
uniprot id: A0A7E6CW58
uniprot id: A0A7E6CWH1
uniprot id: A0A7E6CYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:DYRK1A
gene id: 89673:DYRK1A
uniprot id: A0A6J2L029
uniprot id: A0A6J2L4D4
uniprot id: A0A7E6D4U8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

89673:NPR2
gene id: 89673:NPR2
uniprot id: A0A6J2LCC8
uniprot id: A0A7E6DFJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

89673:LOC114493866
gene id: 89673:LOC114493866
uniprot id: A0A6J2L9N2
names: Similarity
messages: Belongs to the GroES chaperonin family.

89673:PCID2
gene id: 89673:PCID2
uniprot id: A0A6J2MQX2
uniprot id: A0A7E6CKE2
uniprot id: A0A7E6CKI0
uniprot id: A0A7E6CMH6
names: Similarity
messages: Belongs to the CSN12 family.

89673:LOC114507007
gene id: 89673:LOC114507007
uniprot id: A0A7E6CDK6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

89673:LOC114510638
gene id: 89673:LOC114510638
uniprot id: A0A6J2MZF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:HOXA4
gene id: 89673:HOXA4
uniprot id: A0A6J2MPF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:DYNLRB2
gene id: 89673:DYNLRB2
uniprot id: A0A6J2KRH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer.
messages: cytoskeleton

89673:NELFE
gene id: 89673:NELFE
uniprot id: A0A6J2LBS6
uniprot id: A0A7E6DKX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus

89673:DOLK
gene id: 89673:DOLK
uniprot id: A0A6J2MCF3
names: Similarity
messages: Belongs to the polyprenol kinase family.

89673:LOC114489123
gene id: 89673:LOC114489123
uniprot id: A0A6J2KW93
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

89673:MED27
gene id: 89673:MED27
uniprot id: A0A6J2M2G3
uniprot id: A0A7E6DH16
uniprot id: A0A7E6DH54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 27 family.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

89673:STAG1
gene id: 89673:STAG1
uniprot id: A0A6J2M3W1
uniprot id: A0A6J2M832
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

89673:LOC114495442
gene id: 89673:LOC114495442
uniprot id: A0A7E6DNL4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

89673:IGFBP2
gene id: 89673:IGFBP2
uniprot id: A0A6J2LFC6
names: Caution
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:UNCX
gene id: 89673:UNCX
uniprot id: A0A6J2MRY2
names: Subcellular Location Annotation
messages: Nucleus

89673:GABARAPL1
gene id: 89673:GABARAPL1
uniprot id: A0A6J2NE46
names: Similarity
messages: Belongs to the ATG8 family.

89673:NCAPD3
gene id: 89673:NCAPD3
uniprot id: A0A6J2N1B0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the condensin-2 complex.
messages: Nucleus
messages: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.

89673:RYR1
gene id: 89673:RYR1
uniprot id: A0A6J2MYG1
uniprot id: A0A6J2N061
uniprot id: A0A7E6CQ19
uniprot id: A0A7E6CQ71
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

89673:SLC25A29
gene id: 89673:SLC25A29
uniprot id: A0A6J2LAZ6
uniprot id: A0A7E6CSW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:BCAP31
gene id: 89673:BCAP31
uniprot id: A0A6J2MHN7
uniprot id: A0A7E6D1B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.

89673:RAB3D
gene id: 89673:RAB3D
uniprot id: A0A6J2MDH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

89673:EXOSC3
gene id: 89673:EXOSC3
uniprot id: A0A6J2LTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm

89673:NPL
gene id: 89673:NPL
uniprot id: A0A6J2N2L1
uniprot id: A0A7E6CV39
uniprot id: A0A7E6CXW2
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Homotetramer.

89673:LOC114500087
gene id: 89673:LOC114500087
uniprot id: A0A6J2M342
uniprot id: A0A7E6DG44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

89673:LOC114505154
gene id: 89673:LOC114505154
uniprot id: A0A7E6CZV8
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:MAB21L2
gene id: 89673:MAB21L2
uniprot id: A0A6J2M9S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mab-21 family.
messages: Cytoplasm
messages: Nucleus

89673:ZKSCAN8
gene id: 89673:ZKSCAN8
uniprot id: A0A6J2KVP1
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114510243
gene id: 89673:LOC114510243
uniprot id: A0A6J2MYM9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NXPH2
gene id: 89673:NXPH2
uniprot id: A0A7E6DKD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

89673:BCL7A
gene id: 89673:BCL7A
uniprot id: A0A6J2MW36
uniprot id: A0A6J2N1A4
names: Similarity
messages: Belongs to the BCL7 family.

89673:EIF4E1B
gene id: 89673:EIF4E1B
uniprot id: A0A6J2N490
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

89673:LARS2
gene id: 89673:LARS2
uniprot id: A0A6J2M2K2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

89673:SGCA
gene id: 89673:SGCA
uniprot id: A0A6J2ME51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: cytoskeleton

89673:PLP1
gene id: 89673:PLP1
uniprot id: A0A6J2MI19
uniprot id: A0A6J2MLA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

89673:WNT3A
gene id: 89673:WNT3A
uniprot id: A0A6J2NCY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:STARD5
gene id: 89673:STARD5
uniprot id: A0A6J2KS72
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

89673:LOC114505150
gene id: 89673:LOC114505150
uniprot id: A0A7E6D138
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
messages: Heterotetramer of two alpha and two beta chains.

89673:KCNE3
gene id: 89673:KCNE3
uniprot id: A0A6J2LYK6
names: Similarity
messages: Belongs to the potassium channel KCNE family.

89673:LTN1
gene id: 89673:LTN1
uniprot id: A0A6J2L063
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

89673:CYFIP2
gene id: 89673:CYFIP2
uniprot id: A0A6J2MSB9
uniprot id: A0A6J2MYK2
names: Similarity
messages: Belongs to the CYFIP family.

89673:RPS6KB1
gene id: 89673:RPS6KB1
uniprot id: A0A6J2M7Y3
uniprot id: A0A6J2MB90
uniprot id: A0A6J2MBU1
uniprot id: A0A6J2MBU7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

89673:ERMN
gene id: 89673:ERMN
uniprot id: A0A6J2LG19
names: Function
names: Subunit
messages: Binds actin.
messages: Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

89673:CLVS2
gene id: 89673:CLVS2
uniprot id: A0A6J2LFL8
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

89673:PREB
gene id: 89673:PREB
uniprot id: A0A6J2M258
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER.
messages: Interacts with SAR1B (GDP-bound form). Interacts with MIA2; recruits PREB to endoplasmic reticulum exit sites.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription.

89673:POLR3GL
gene id: 89673:POLR3GL
uniprot id: A0A6J2KUG1
uniprot id: A0A6J2KYA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

89673:FAM13B
gene id: 89673:FAM13B
uniprot id: A0A6J2MXT5
uniprot id: A0A6J2MXU0
uniprot id: A0A6J2MXW0
uniprot id: A0A6J2N360
uniprot id: A0A7E6CUJ2
uniprot id: A0A7E6CUJ3
uniprot id: A0A7E6CUJ8
uniprot id: A0A7E6CV16
uniprot id: A0A7E6CV18
uniprot id: A0A7E6CVB9
uniprot id: A0A7E6CXB7
names: Similarity
messages: Belongs to the FAM13 family.

89673:LOC114499356
gene id: 89673:LOC114499356
uniprot id: A0A7E6DAH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:KCNAB1
gene id: 89673:KCNAB1
uniprot id: A0A6J2L417
uniprot id: A0A6J2L5I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

89673:SUSD6
gene id: 89673:SUSD6
uniprot id: A0A6J2LD63
uniprot id: A0A7E6CMA7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114515321
gene id: 89673:LOC114515321
uniprot id: A0A7E6EB76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

89673:WARS2
gene id: 89673:WARS2
uniprot id: A0A6J2KZ11
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

89673:HMGN1
gene id: 89673:HMGN1
uniprot id: A0A6J2L0I4
uniprot id: A0A7E6D4V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

89673:ENPP1
gene id: 89673:ENPP1
uniprot id: A0A6J2LHG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Secreted

89673:LOC114505727
gene id: 89673:LOC114505727
uniprot id: A0A6J2MIV9
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

89673:LOC118498385
gene id: 89673:LOC118498385
uniprot id: A0A7E6CZT0
names: Function
names: Similarity
messages: Belongs to the SSX family.
messages: Could act as a modulator of transcription.

89673:COPG2
gene id: 89673:COPG2
uniprot id: A0A6J2MT94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

89673:SLC25A11
gene id: 89673:SLC25A11
uniprot id: A0A6J2NDU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:MRFAP1
gene id: 89673:MRFAP1
uniprot id: A0A6J2L318
names: Similarity
messages: Belongs to the MORF4 family-associated protein family.

89673:ABCC9
gene id: 89673:ABCC9
uniprot id: A0A6J2N6U5
uniprot id: A0A6J2N8K7
uniprot id: A0A7E6D794
uniprot id: A0A7E6D7G5
uniprot id: A0A7E6D7Z8
names: Subunit
messages: Interacts with KCNJ11.

89673:RNASEH2B
gene id: 89673:RNASEH2B
uniprot id: A0A6J2MX54
uniprot id: A0A7E6CK00
uniprot id: A0A7E6CK04
uniprot id: A0A7E6CK10
uniprot id: A0A7E6CK15
uniprot id: A0A7E6CK21
uniprot id: A0A7E6CK44
uniprot id: A0A7E6CK49
uniprot id: A0A7E6CM27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

89673:LOC114500582
gene id: 89673:LOC114500582
uniprot id: A0A6J2M0K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PHACTR4
gene id: 89673:PHACTR4
uniprot id: A0A7E6DQL9
uniprot id: A0A7E6DQP4
uniprot id: A0A7E6DRC0
uniprot id: A0A7E6DRE3
uniprot id: A0A7E6DRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

89673:PRKAR2A
gene id: 89673:PRKAR2A
uniprot id: A0A6J2M4Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

89673:IMPG1
gene id: 89673:IMPG1
uniprot id: A0A7E6DMA8
uniprot id: A0A7E6DMB2
uniprot id: A0A7E6DMR5
uniprot id: A0A7E6DN42
names: Subcellular Location Annotation
messages: interphotoreceptor matrix

89673:LOC114497930
gene id: 89673:LOC114497930
uniprot id: A0A6J2LQW3
uniprot id: A0A7E6DVI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

89673:LTBR
gene id: 89673:LTBR
uniprot id: A0A6J2N5B7
uniprot id: A0A6J2NBW7
uniprot id: A0A7E6D1Y5
uniprot id: A0A7E6D2N8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:KMT5B
gene id: 89673:KMT5B
uniprot id: A0A6J2LVI0
uniprot id: A0A7E6E2V1
uniprot id: A0A7E6E334
uniprot id: A0A7E6E3R6
uniprot id: A0A7E6E3R9
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

89673:GALT
gene id: 89673:GALT
uniprot id: A0A6J2LKT0
uniprot id: A0A6J2LVD1
uniprot id: A0A7E6DFD7
uniprot id: A0A7E6DFE5
uniprot id: A0A7E6DFG3
uniprot id: A0A7E6DFI4
uniprot id: A0A7E6DFI8
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.
messages: Binds 1 Fe cation per subunit.

89673:MARK3
gene id: 89673:MARK3
uniprot id: A0A6J2L1K0
uniprot id: A0A7E6CSN8
uniprot id: A0A7E6CSP0
uniprot id: A0A7E6CT61
uniprot id: A0A7E6CVF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

89673:LOC114490682
gene id: 89673:LOC114490682
uniprot id: A0A6J2L2N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.

89673:SERPINB1
gene id: 89673:SERPINB1
uniprot id: A0A6J2LSE3
uniprot id: A0A7E6DU21
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

89673:FLVCR1
gene id: 89673:FLVCR1
uniprot id: A0A6J2N9A3
uniprot id: A0A7E6D091
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114492778
gene id: 89673:LOC114492778
uniprot id: A0A6J2L5Y7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:LOC114509830
gene id: 89673:LOC114509830
uniprot id: A0A6J2MX58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

89673:SH3BGR
gene id: 89673:SH3BGR
uniprot id: A0A6J2L082
names: Similarity
messages: Belongs to the SH3BGR family.

89673:SEMA7A
gene id: 89673:SEMA7A
uniprot id: A0A6J2L901
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:PRPF38A
gene id: 89673:PRPF38A
uniprot id: A0A6J2LNL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

89673:S100A16
gene id: 89673:S100A16
uniprot id: A0A6J2KWE6
names: Similarity
messages: Belongs to the S-100 family.

89673:LOC114494739
gene id: 89673:LOC114494739
uniprot id: A0A7E6DAH0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:SLC9A8
gene id: 89673:SLC9A8
uniprot id: A0A6J2MRX4
uniprot id: A0A7E6CI02
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

89673:RAB39B
gene id: 89673:RAB39B
uniprot id: A0A6J2MFX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

89673:LOC118498778
gene id: 89673:LOC118498778
uniprot id: A0A7E6D329
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:LOC114491859
gene id: 89673:LOC114491859
uniprot id: A0A7E6DDY1
uniprot id: A0A7E6DDZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

89673:LOC114500287
gene id: 89673:LOC114500287
uniprot id: A0A6J2M3E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114515301
gene id: 89673:LOC114515301
uniprot id: A0A7E6CXR5
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

89673:EHD2
gene id: 89673:EHD2
uniprot id: A0A6J2N1A0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

89673:LOC114500779
gene id: 89673:LOC114500779
uniprot id: A0A7E6D9E2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

89673:KCNA4
gene id: 89673:KCNA4
uniprot id: A0A6J2M0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

89673:TMEM50A
gene id: 89673:TMEM50A
uniprot id: A0A6J2LLC8
uniprot id: A0A7E6DR73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

89673:LOC114488219
gene id: 89673:LOC114488219
uniprot id: A0A6J2KQI3
uniprot id: A0A7E6CLY1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

89673:TMEM132A
gene id: 89673:TMEM132A
uniprot id: A0A6J2LVX6
uniprot id: A0A6J2LX15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

89673:DDX43
gene id: 89673:DDX43
uniprot id: A0A6J2LK49
names: Similarity
messages: Belongs to the DEAD box helicase family.

89673:GDPD2
gene id: 89673:GDPD2
uniprot id: A0A6J2MF64
uniprot id: A0A7E6CZD7
uniprot id: A0A7E6CZP7
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

89673:MCF2L
gene id: 89673:MCF2L
uniprot id: A0A6J2MRK0
uniprot id: A0A6J2MRK4
uniprot id: A0A6J2MRK9
uniprot id: A0A6J2MRL4
uniprot id: A0A6J2MT98
uniprot id: A0A6J2MTB0
uniprot id: A0A6J2MTB1
uniprot id: A0A6J2MTB3
uniprot id: A0A6J2MTB4
uniprot id: A0A6J2MTB8
uniprot id: A0A6J2MXU6
uniprot id: A0A6J2MXV1
uniprot id: A0A6J2MXW1
uniprot id: A0A6J2MYA3
uniprot id: A0A6J2MYB1
uniprot id: A0A6J2MYB6
uniprot id: A0A7E6CKC3
uniprot id: A0A7E6CKD7
uniprot id: A0A7E6CKD9
uniprot id: A0A7E6CKE3
uniprot id: A0A7E6CKE5
uniprot id: A0A7E6CKH2
uniprot id: A0A7E6CMF9
uniprot id: A0A7E6CMG4
uniprot id: A0A7E6CMH0
names: Subcellular Location Annotation
messages: Cytoplasm

89673:OVOL3
gene id: 89673:OVOL3
uniprot id: A0A7E6CNW5
names: Subcellular Location Annotation
messages: Nucleus

89673:TGFA
gene id: 89673:TGFA
uniprot id: A0A7E6DYN4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114513025
gene id: 89673:LOC114513025
uniprot id: A0A6J2N7R9
names: Similarity
messages: Belongs to the intermediate filament family.

89673:LOC114496718
gene id: 89673:LOC114496718
uniprot id: A0A6J2LQU3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

89673:ERLEC1
gene id: 89673:ERLEC1
uniprot id: A0A6J2M0H0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

89673:STX11
gene id: 89673:STX11
uniprot id: A0A6J2LI55
names: Similarity
messages: Belongs to the syntaxin family.

89673:LOC114509180
gene id: 89673:LOC114509180
uniprot id: A0A6J2MYW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

89673:LOC114504744
gene id: 89673:LOC114504744
uniprot id: A0A6J2MGF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

89673:MYCL
gene id: 89673:MYCL
uniprot id: A0A6J2LUM4
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

89673:NOP14
gene id: 89673:NOP14
uniprot id: A0A6J2KYA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

89673:LOC114502882
gene id: 89673:LOC114502882
uniprot id: A0A6J2M7G6
names: Similarity
messages: Belongs to the intermediate filament family.

89673:TAGLN
gene id: 89673:TAGLN
uniprot id: A0A6J2M0Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calponin family.
messages: Cytoplasm

89673:P4HA2
gene id: 89673:P4HA2
uniprot id: A0A6J2N355
uniprot id: A0A7E6CUL9
uniprot id: A0A7E6CXE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

89673:NUDC
gene id: 89673:NUDC
uniprot id: A0A6J2LL34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudC family.
messages: Midbody
messages: spindle

89673:B3GAT2
gene id: 89673:B3GAT2
uniprot id: A0A6J2LCI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC114497985
gene id: 89673:LOC114497985
uniprot id: A0A7E6DSK3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC118496630
gene id: 89673:LOC118496630
uniprot id: A0A7E6CZN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP10 subfamily.
messages: Cytoplasm
messages: Nucleus

89673:MZF1
gene id: 89673:MZF1
uniprot id: A0A6J2N343
uniprot id: A0A7E6CR11
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114499700
gene id: 89673:LOC114499700
uniprot id: A0A7E6E0I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

89673:LOC114500346
gene id: 89673:LOC114500346
uniprot id: A0A6J2LYK1
names: Similarity
messages: Belongs to the folate receptor family.

89673:OAT
gene id: 89673:OAT
uniprot id: A0A6J2LQV2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

89673:ACE2
gene id: 89673:ACE2
uniprot id: A0A7E6CZX5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

89673:VRK1
gene id: 89673:VRK1
uniprot id: A0A6J2LAY9
uniprot id: A0A7E6CSJ2
uniprot id: A0A7E6CUJ0
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:MRPS17
gene id: 89673:MRPS17
uniprot id: A0A6J2LS17
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

89673:ALLC
gene id: 89673:ALLC
uniprot id: A0A6J2M610
names: Function
names: Similarity
messages: Belongs to the allantoicase family.
messages: The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals.

89673:ACTA2
gene id: 89673:ACTA2
uniprot id: A0A6J2LMS2
names: Similarity
messages: Belongs to the actin family.

89673:SCAMP1
gene id: 89673:SCAMP1
uniprot id: A0A6J2LN94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

89673:DCAF11
gene id: 89673:DCAF11
uniprot id: A0A7E6E2V5
uniprot id: A0A7E6E4G9
uniprot id: A0A7E6E4H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat LEC14B family.
messages: Interacts with DDB1 and CUL4A.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

89673:TNFRSF11B
gene id: 89673:TNFRSF11B
uniprot id: A0A6J2NID7
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:IYD
gene id: 89673:IYD
uniprot id: A0A6J2LHY9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasmic vesicle membrane

89673:NUP155
gene id: 89673:NUP155
uniprot id: A0A6J2MNJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

89673:PLCB1
gene id: 89673:PLCB1
uniprot id: A0A6J2MIQ0
uniprot id: A0A6J2MPW4
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

89673:VWDE
gene id: 89673:VWDE
uniprot id: A0A7E6CJH0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114499233
gene id: 89673:LOC114499233
uniprot id: A0A6J2LYF8
names: Similarity
messages: Belongs to the OSBP family.

89673:GPI
gene id: 89673:GPI
uniprot id: A0A6J2N4K4
names: Similarity
messages: Belongs to the GPI family.

89673:SRF
gene id: 89673:SRF
uniprot id: A0A6J2LA15
names: Subcellular Location Annotation
messages: Nucleus

89673:DMTN
gene id: 89673:DMTN
uniprot id: A0A6J2MA43
uniprot id: A0A6J2MA47
uniprot id: A0A6J2MCC2
uniprot id: A0A6J2MF70
uniprot id: A0A7E6EB67
uniprot id: A0A7E6EBU5
uniprot id: A0A7E6EC96
names: Subcellular Location Annotation
messages: Cytoplasm

89673:CWF19L1
gene id: 89673:CWF19L1
uniprot id: A0A6J2LQB2
uniprot id: A0A6J2LUG8
uniprot id: A0A7E6DVJ3
names: Similarity
messages: Belongs to the CWF19 family.

89673:LOC114490330
gene id: 89673:LOC114490330
uniprot id: A0A6J2KXF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ATP6V0A1
gene id: 89673:ATP6V0A1
uniprot id: A0A6J2M5L6
uniprot id: A0A6J2M730
uniprot id: A0A6J2M7I3
uniprot id: A0A6J2MAE9
uniprot id: A0A7E6EEJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

89673:HIKESHI
gene id: 89673:HIKESHI
uniprot id: A0A6J2M4H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

89673:LOC114497973
gene id: 89673:LOC114497973
uniprot id: A0A6J2LS07
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

89673:PELI2
gene id: 89673:PELI2
uniprot id: A0A6J2L735
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

89673:MIEF2
gene id: 89673:MIEF2
uniprot id: A0A6J2NJM2
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

89673:CDC14A
gene id: 89673:CDC14A
uniprot id: A0A6J2KV58
uniprot id: A0A6J2KYZ1
uniprot id: A0A7E6CXK2
uniprot id: A0A7E6CY24
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

89673:BCL2L1
gene id: 89673:BCL2L1
uniprot id: A0A6J2MRR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane
messages: Mitochondrion matrix
messages: Nucleus membrane
messages: centrosome
messages: cytosol
messages: synaptic vesicle membrane

89673:RPS9
gene id: 89673:RPS9
uniprot id: A0A7E6CR28
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs.

89673:LOC114489919
gene id: 89673:LOC114489919
uniprot id: A0A7E6D320
uniprot id: A0A7E6D347
uniprot id: A0A7E6D3N7
uniprot id: A0A7E6D3R5
names: Subcellular Location Annotation
messages: Nucleus

89673:STIP1
gene id: 89673:STIP1
uniprot id: A0A6J2LZ48
uniprot id: A0A6J2M4N8
names: Subcellular Location Annotation
messages: Cytoplasm

89673:WNT3
gene id: 89673:WNT3
uniprot id: A0A6J2MBC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:SLC35F1
gene id: 89673:SLC35F1
uniprot id: A0A6J2LLX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

89673:SLC43A2
gene id: 89673:SLC43A2
uniprot id: A0A6J2M7S1
uniprot id: A0A6J2MD27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC43A transporter (TC 2.A.1.44) family.
messages: Membrane

89673:CACNG5
gene id: 89673:CACNG5
uniprot id: A0A6J2MBN5
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

89673:GET1
gene id: 89673:GET1
uniprot id: A0A6J2L3Q3
uniprot id: A0A7E6D234
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:OTOP2
gene id: 89673:OTOP2
uniprot id: A0A6J2MCQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

89673:CD81
gene id: 89673:CD81
uniprot id: A0A6J2M0S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:GALNT12
gene id: 89673:GALNT12
uniprot id: A0A6J2KVT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:RPL34
gene id: 89673:RPL34
uniprot id: A0A6J2L4L7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

89673:LOC114497501
gene id: 89673:LOC114497501
uniprot id: A0A6J2LMS7
names: Similarity
messages: Belongs to the serpin family.

89673:FZD6
gene id: 89673:FZD6
uniprot id: A0A6J2NB85
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:A4GNT
gene id: 89673:A4GNT
uniprot id: A0A6J2M694
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

89673:GLIS1
gene id: 89673:GLIS1
uniprot id: A0A6J2LM86
uniprot id: A0A7E6DT89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

89673:REV1
gene id: 89673:REV1
uniprot id: A0A6J2LRK2
uniprot id: A0A6J2LST9
uniprot id: A0A7E6DY91
uniprot id: A0A7E6DYS0
uniprot id: A0A7E6DZM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

89673:KLHL22
gene id: 89673:KLHL22
uniprot id: A0A6J2MTW2
names: Subcellular Location Annotation
messages: Lysosome
messages: Nucleus
messages: centrosome
messages: cytosol
messages: spindle

89673:ANKRD34A
gene id: 89673:ANKRD34A
uniprot id: A0A6J2L0C6
uniprot id: A0A7E6CW14
names: Similarity
messages: Belongs to the ANKRD34 family.

89673:UCHL5
gene id: 89673:UCHL5
uniprot id: A0A6J2N5M1
uniprot id: A0A6J2NB28
uniprot id: A0A7E6CY62
names: Similarity
messages: Belongs to the peptidase C12 family.

89673:DDX58
gene id: 89673:DDX58
uniprot id: A0A6J2N297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

89673:LOC114492938
gene id: 89673:LOC114492938
uniprot id: A0A6J2L8P1
names: Subcellular Location Annotation
messages: Secreted

89673:PACS2
gene id: 89673:PACS2
uniprot id: A0A6J2L8P5
uniprot id: A0A7E6CT51
uniprot id: A0A7E6CT58
uniprot id: A0A7E6CT71
uniprot id: A0A7E6CVZ0
uniprot id: A0A7E6CW05
names: Similarity
messages: Belongs to the PACS family.

89673:HARS1
gene id: 89673:HARS1
uniprot id: A0A6J2MSK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

89673:MAF
gene id: 89673:MAF
uniprot id: A0A6J2KW08
uniprot id: A0A7E6CPB7
uniprot id: A0A7E6CPC9
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

89673:SYCE1
gene id: 89673:SYCE1
uniprot id: A0A7E6DWH4
names: Similarity
messages: Belongs to the SYCE family.

89673:GNPTAB
gene id: 89673:GNPTAB
uniprot id: A0A6J2NCR3
uniprot id: A0A7E6D7Y1
uniprot id: A0A7E6D839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stealth family.
messages: Membrane

89673:GUCY1A1
gene id: 89673:GUCY1A1
uniprot id: A0A6J2MCK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

89673:KCNH5
gene id: 89673:KCNH5
uniprot id: A0A7E6CIM5
names: Subcellular Location Annotation
messages: Membrane

89673:FAM216B
gene id: 89673:FAM216B
uniprot id: A0A6J2MVQ3
names: Similarity
messages: Belongs to the FAM216 family.

89673:MRPL50
gene id: 89673:MRPL50
uniprot id: A0A6J2MCV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

89673:LOC114499878
gene id: 89673:LOC114499878
uniprot id: A0A6J2LXW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DIPK1A
gene id: 89673:DIPK1A
uniprot id: A0A6J2LHH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

89673:NLRP9
gene id: 89673:NLRP9
uniprot id: A0A6J2MZU4
names: Similarity
messages: Belongs to the NLRP family.

89673:PARN
gene id: 89673:PARN
uniprot id: A0A6J2LNK8
uniprot id: A0A7E6DBP5
uniprot id: A0A7E6DDJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Cytoplasm
messages: Nucleus

89673:KRT19
gene id: 89673:KRT19
uniprot id: A0A6J2MHD5
names: Similarity
messages: Belongs to the intermediate filament family.

89673:TAF10
gene id: 89673:TAF10
uniprot id: A0A6J2M3X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus
messages: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.

89673:ZDHHC18
gene id: 89673:ZDHHC18
uniprot id: A0A6J2LNL5
uniprot id: A0A7E6DR85
uniprot id: A0A7E6DRA6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:LOC114509551
gene id: 89673:LOC114509551
uniprot id: A0A6J2MVU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCHP family.
messages: cytoskeleton

89673:LOC114491038
gene id: 89673:LOC114491038
uniprot id: A0A7E6DEG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ATP8A1
gene id: 89673:ATP8A1
uniprot id: A0A6J2L0K6
uniprot id: A0A6J2L4W9
uniprot id: A0A7E6DAI8
uniprot id: A0A7E6DCK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

89673:LOC114512994
gene id: 89673:LOC114512994
uniprot id: A0A6J2ND56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SH2D1A
gene id: 89673:SH2D1A
uniprot id: A0A6J2MFA5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.

89673:LOC114503734
gene id: 89673:LOC114503734
uniprot id: A0A7E6EAP6
uniprot id: A0A7E6EAW7
uniprot id: A0A7E6EBI5
names: Subcellular Location Annotation
messages: clathrin-coated pit

89673:CACNG4
gene id: 89673:CACNG4
uniprot id: A0A6J2M9D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

89673:LOC114497410
gene id: 89673:LOC114497410
uniprot id: A0A7E6DTF1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

89673:RNF126
gene id: 89673:RNF126
uniprot id: A0A6J2M6M9
uniprot id: A0A6J2M801
uniprot id: A0A6J2MBB3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:EXOG
gene id: 89673:EXOG
uniprot id: A0A6J2M2R9
uniprot id: A0A6J2M489
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

89673:PRRT1
gene id: 89673:PRRT1
uniprot id: A0A6J2LDI7
uniprot id: A0A6J2LEH0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:LOC114493084
gene id: 89673:LOC114493084
uniprot id: A0A6J2L7Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

89673:DERL1
gene id: 89673:DERL1
uniprot id: A0A6J2NCV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

89673:LOC114505000
gene id: 89673:LOC114505000
uniprot id: A0A7E6CZV1
names: Subcellular Location Annotation
messages: Mitochondrion

89673:PAXBP1
gene id: 89673:PAXBP1
uniprot id: A0A6J2L299
names: Similarity
messages: Belongs to the GCF family.

89673:ATRN
gene id: 89673:ATRN
uniprot id: A0A6J2MK31
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:PDE6C
gene id: 89673:PDE6C
uniprot id: A0A6J2LN25
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:WNT10A
gene id: 89673:WNT10A
uniprot id: A0A6J2LJ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:ATP11A
gene id: 89673:ATP11A
uniprot id: A0A6J2MQ38
uniprot id: A0A7E6CKB8
uniprot id: A0A7E6CKD3
uniprot id: A0A7E6CKD5
uniprot id: A0A7E6CKE0
uniprot id: A0A7E6CKG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

89673:MFAP1
gene id: 89673:MFAP1
uniprot id: A0A6J2L484
names: Function
names: Similarity
messages: Belongs to the MFAP1 family.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.

89673:RAB33A
gene id: 89673:RAB33A
uniprot id: A0A6J2MEC4
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

89673:LEPROT
gene id: 89673:LEPROT
uniprot id: A0A6J2LPU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

89673:SCD5
gene id: 89673:SCD5
uniprot id: A0A6J2L4E1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

89673:HIGD2A
gene id: 89673:HIGD2A
uniprot id: A0A6J2N0C5
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

89673:SLC2A12
gene id: 89673:SLC2A12
uniprot id: A0A6J2LE66
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

89673:SYNGR2
gene id: 89673:SYNGR2
uniprot id: A0A6J2M9M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

89673:PPIC
gene id: 89673:PPIC
uniprot id: A0A6J2M7F4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:POLH
gene id: 89673:POLH
uniprot id: A0A6J2LEQ5
names: Subcellular Location Annotation
messages: Nucleus

89673:TATDN3
gene id: 89673:TATDN3
uniprot id: A0A6J2N3Y6
uniprot id: A0A6J2N9E5
uniprot id: A0A7E6CUY9
uniprot id: A0A7E6CUZ6
uniprot id: A0A7E6CUZ9
uniprot id: A0A7E6CVG7
uniprot id: A0A7E6CVQ9
uniprot id: A0A7E6CVR4
uniprot id: A0A7E6CXS2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

89673:LOC114500703
gene id: 89673:LOC114500703
uniprot id: A0A6J2M1W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:GMPR2
gene id: 89673:GMPR2
uniprot id: A0A6J2L9T8
uniprot id: A0A6J2LB25
uniprot id: A0A7E6E377
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:USE1
gene id: 89673:USE1
uniprot id: A0A6J2M7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:PGB
gene id: 89673:PGB
uniprot id: A0A6J2KV29
uniprot id: A0A6J2L0F4
names: Similarity
messages: Belongs to the peptidase A1 family.

89673:TRAK1
gene id: 89673:TRAK1
uniprot id: A0A6J2M6L4
uniprot id: A0A6J2M6L9
uniprot id: A0A6J2M771
uniprot id: A0A7E6E4S7
uniprot id: A0A7E6E4X0
uniprot id: A0A7E6E5Q2
uniprot id: A0A7E6E5W0
uniprot id: A0A7E6E5W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

89673:ASPHD1
gene id: 89673:ASPHD1
uniprot id: A0A6J2LBG9
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

89673:LOC114500163
gene id: 89673:LOC114500163
uniprot id: A0A6J2LZ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:INSL3
gene id: 89673:INSL3
uniprot id: A0A6J2MHW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted
messages: Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.

89673:DLK2
gene id: 89673:DLK2
uniprot id: A0A6J2LHG9
uniprot id: A0A7E6DMC7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TMPRSS3
gene id: 89673:TMPRSS3
uniprot id: A0A6J2L1B5
uniprot id: A0A6J2L352
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:NIPA1
gene id: 89673:NIPA1
uniprot id: A0A6J2KW89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

89673:MIS12
gene id: 89673:MIS12
uniprot id: A0A6J2NEN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mis12 family.
messages: Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Also interacts with KNL1, CBX3, CBX5, NDC80 and ZWINT.
messages: kinetochore

89673:SEZ6L
gene id: 89673:SEZ6L
uniprot id: A0A6J2MUM3
uniprot id: A0A7E6CUU2
uniprot id: A0A7E6CVB2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GSS
gene id: 89673:GSS
uniprot id: A0A6J2MKT8
uniprot id: A0A6J2MMK8
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

89673:LOC114494581
gene id: 89673:LOC114494581
uniprot id: A0A6J2LF71
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

89673:TNS1
gene id: 89673:TNS1
uniprot id: A0A6J2LGA4
uniprot id: A0A6J2LIN6
uniprot id: A0A7E6DI54
uniprot id: A0A7E6DI83
uniprot id: A0A7E6DI87
uniprot id: A0A7E6DI93
uniprot id: A0A7E6DID4
uniprot id: A0A7E6DID8
uniprot id: A0A7E6DID9
uniprot id: A0A7E6DIE3
uniprot id: A0A7E6DIE4
uniprot id: A0A7E6DIE7
uniprot id: A0A7E6DIF1
uniprot id: A0A7E6DIH8
uniprot id: A0A7E6DII2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

89673:BAZ1A
gene id: 89673:BAZ1A
uniprot id: A0A6J2L990
names: Subcellular Location Annotation
messages: Nucleus

89673:PUS7
gene id: 89673:PUS7
uniprot id: A0A6J2MM96
uniprot id: A0A6J2MP70
uniprot id: A0A7E6CK82
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

89673:ADRA2C
gene id: 89673:ADRA2C
uniprot id: A0A6J2KW54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:MTHFD1
gene id: 89673:MTHFD1
uniprot id: A0A6J2L3C2
uniprot id: A0A6J2L6M2
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

89673:LOC114495531
gene id: 89673:LOC114495531
uniprot id: A0A6J2LLH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

89673:ABCG1
gene id: 89673:ABCG1
uniprot id: A0A6J2L0B4
uniprot id: A0A6J2L1Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

89673:CHST3
gene id: 89673:CHST3
uniprot id: A0A6J2LK07
uniprot id: A0A7E6DV10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

89673:BTN1A1
gene id: 89673:BTN1A1
uniprot id: A0A6J2KX97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:LBR
gene id: 89673:LBR
uniprot id: A0A6J2NB39
uniprot id: A0A7E6CYJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus inner membrane

89673:LOC114501000
gene id: 89673:LOC114501000
uniprot id: A0A6J2M2N1
uniprot id: A0A7E6E210
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114496070
gene id: 89673:LOC114496070
uniprot id: A0A6J2LM42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

89673:MLF2
gene id: 89673:MLF2
uniprot id: A0A6J2N673
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

89673:UBAC2
gene id: 89673:UBAC2
uniprot id: A0A6J2MRP5
uniprot id: A0A6J2MW32
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114494138
gene id: 89673:LOC114494138
uniprot id: A0A6J2LAT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline phosphatase family.
messages: Cell membrane
messages: Membrane

89673:LOC114489251
gene id: 89673:LOC114489251
uniprot id: A0A6J2KYE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:CPEB4
gene id: 89673:CPEB4
uniprot id: A0A6J2MUG8
uniprot id: A0A6J2MUI4
uniprot id: A0A6J2MZ32
uniprot id: A0A6J2MZJ9
names: Similarity
messages: Belongs to the RRM CPEB family.

89673:LOC118502053
gene id: 89673:LOC118502053
uniprot id: A0A7E6EC80
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

89673:LOC114509771
gene id: 89673:LOC114509771
uniprot id: A0A6J2MWY2
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114505025
gene id: 89673:LOC114505025
uniprot id: A0A7E6D096
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

89673:NEU3
gene id: 89673:NEU3
uniprot id: A0A6J2LVV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

89673:TMC7
gene id: 89673:TMC7
uniprot id: A0A6J2MX37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

89673:CEL
gene id: 89673:CEL
uniprot id: A0A6J2MSL5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

89673:TRPV1
gene id: 89673:TRPV1
uniprot id: A0A6J2NJI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV1 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendritic spine membrane

89673:AK6
gene id: 89673:AK6
uniprot id: A0A6J2L3B3
uniprot id: A0A7E6DAN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

89673:LOC114504831
gene id: 89673:LOC114504831
uniprot id: A0A7E6D372
names: Similarity
messages: Belongs to the SPT20 family.

89673:SPX
gene id: 89673:SPX
uniprot id: A0A7E6DA73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

89673:LRP5
gene id: 89673:LRP5
uniprot id: A0A6J2LRS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:APC2
gene id: 89673:APC2
uniprot id: A0A6J2M7H7
uniprot id: A0A6J2MCU0
uniprot id: A0A7E6EAB5
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

89673:PRRX2
gene id: 89673:PRRX2
uniprot id: A0A6J2MAD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

89673:TMEM205
gene id: 89673:TMEM205
uniprot id: A0A6J2MCK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

89673:LEF1
gene id: 89673:LEF1
uniprot id: A0A6J2L3J3
uniprot id: A0A6J2L477
uniprot id: A0A6J2L849
uniprot id: A0A6J2L9J9
uniprot id: A0A7E6DR69
uniprot id: A0A7E6DR89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

89673:TMEM126B
gene id: 89673:TMEM126B
uniprot id: A0A6J2LWP7
uniprot id: A0A7E6DZJ1
uniprot id: A0A7E6DZJ4
uniprot id: A0A7E6E0H9
uniprot id: A0A7E6E0R4
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114494311
gene id: 89673:LOC114494311
uniprot id: A0A7E6DNC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

89673:LOC114507464
gene id: 89673:LOC114507464
uniprot id: A0A7E6CIZ8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:TMEM43
gene id: 89673:TMEM43
uniprot id: A0A6J2M5T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

89673:LOC114503381
gene id: 89673:LOC114503381
uniprot id: A0A6J2MEK2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114512080
gene id: 89673:LOC114512080
uniprot id: A0A6J2NA17
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PDIA6
gene id: 89673:PDIA6
uniprot id: A0A6J2LUM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

89673:VKORC1L1
gene id: 89673:VKORC1L1
uniprot id: A0A6J2LJD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:TMEM242
gene id: 89673:TMEM242
uniprot id: A0A6J2LHP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

89673:LOC114500877
gene id: 89673:LOC114500877
uniprot id: A0A6J2M1J2
names: Subcellular Location Annotation
messages: Membrane

89673:CSTF2
gene id: 89673:CSTF2
uniprot id: A0A6J2MGJ0
uniprot id: A0A6J2MJS7
uniprot id: A0A7E6D1I7
uniprot id: A0A7E6D2A5
names: Subcellular Location Annotation
messages: Nucleus

89673:IDS
gene id: 89673:IDS
uniprot id: A0A6J2MFM7
uniprot id: A0A6J2MLN9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

89673:LOC114495065
gene id: 89673:LOC114495065
uniprot id: A0A7E6DHH7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

89673:GPX1
gene id: 89673:GPX1
uniprot id: A0A6J2M6K9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

89673:SFRP1
gene id: 89673:SFRP1
uniprot id: A0A6J2MT86
uniprot id: A0A7E6CKQ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:CLUAP1
gene id: 89673:CLUAP1
uniprot id: A0A6J2LKS9
uniprot id: A0A6J2LKT6
uniprot id: A0A7E6D978
uniprot id: A0A7E6D9B1
uniprot id: A0A7E6D9H2
uniprot id: A0A7E6DA61
uniprot id: A0A7E6DC85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

89673:SCUBE1
gene id: 89673:SCUBE1
uniprot id: A0A6J2N635
uniprot id: A0A6J2N7V1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:A4GALT
gene id: 89673:A4GALT
uniprot id: A0A6J2N9U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

89673:KRTCAP2
gene id: 89673:KRTCAP2
uniprot id: A0A6J2KVD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRTCAP2 family.
messages: Membrane

89673:LOC114499054
gene id: 89673:LOC114499054
uniprot id: A0A7E6E3F5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:VIPAS39
gene id: 89673:VIPAS39
uniprot id: A0A6J2L6K5
uniprot id: A0A6J2L7A8
uniprot id: A0A7E6CNV7
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Vesicle

89673:CD5
gene id: 89673:CD5
uniprot id: A0A7E6E4H9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RECQL5
gene id: 89673:RECQL5
uniprot id: A0A6J2M7Y5
uniprot id: A0A7E6EG69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

89673:E2F3
gene id: 89673:E2F3
uniprot id: A0A6J2LNS3
uniprot id: A0A7E6DT66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

89673:LOC114513005
gene id: 89673:LOC114513005
uniprot id: A0A6J2NCI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114488121
gene id: 89673:LOC114488121
uniprot id: A0A7E6CMG3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

89673:GLRA3
gene id: 89673:GLRA3
uniprot id: A0A6J2MA23
uniprot id: A0A6J2MC32
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

89673:LOC114499040
gene id: 89673:LOC114499040
uniprot id: A0A6J2LXU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:YME1L1
gene id: 89673:YME1L1
uniprot id: A0A6J2L5Q1
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

89673:PTPRD
gene id: 89673:PTPRD
uniprot id: A0A6J2LZR3
uniprot id: A0A7E6DEN2
uniprot id: A0A7E6DEN8
uniprot id: A0A7E6DEP3
uniprot id: A0A7E6DEP5
uniprot id: A0A7E6DEP8
uniprot id: A0A7E6DEP9
uniprot id: A0A7E6DEQ1
uniprot id: A0A7E6DEQ4
uniprot id: A0A7E6DEQ6
uniprot id: A0A7E6DEQ9
uniprot id: A0A7E6DER1
uniprot id: A0A7E6DER2
uniprot id: A0A7E6DER4
uniprot id: A0A7E6DER6
uniprot id: A0A7E6DER7
uniprot id: A0A7E6DER9
uniprot id: A0A7E6DES1
uniprot id: A0A7E6DES2
uniprot id: A0A7E6DES3
uniprot id: A0A7E6DES5
uniprot id: A0A7E6DES7
uniprot id: A0A7E6DES8
uniprot id: A0A7E6DES9
uniprot id: A0A7E6DET2
uniprot id: A0A7E6DET4
uniprot id: A0A7E6DET5
uniprot id: A0A7E6DET6
uniprot id: A0A7E6DET7
uniprot id: A0A7E6DEU0
uniprot id: A0A7E6DEU1
uniprot id: A0A7E6DEU2
uniprot id: A0A7E6DEU5
uniprot id: A0A7E6DEU6
uniprot id: A0A7E6DEU8
uniprot id: A0A7E6DEV0
uniprot id: A0A7E6DEV2
uniprot id: A0A7E6DEV3
uniprot id: A0A7E6DEV7
uniprot id: A0A7E6DEV9
uniprot id: A0A7E6DEW2
uniprot id: A0A7E6DEW5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

89673:CD3E
gene id: 89673:CD3E
uniprot id: A0A7E6DZA4
uniprot id: A0A7E6DZS0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:RHCE
gene id: 89673:RHCE
uniprot id: A0A6J2LTB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

89673:PTCD2
gene id: 89673:PTCD2
uniprot id: A0A7E6DAC1
uniprot id: A0A7E6DBH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTCD2 family.
messages: Mitochondrion

89673:C4H6orf89
gene id: 89673:C4H6orf89
uniprot id: A0A6J2LDZ1
uniprot id: A0A7E6DLD1
uniprot id: A0A7E6DLD5
uniprot id: A0A7E6DLR4
uniprot id: A0A7E6DLU7
uniprot id: A0A7E6DM38
uniprot id: A0A7E6DM43
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

89673:PPIL6
gene id: 89673:PPIL6
uniprot id: A0A7E6DN89
uniprot id: A0A7E6DNN9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:PRR5
gene id: 89673:PRR5
uniprot id: A0A6J2N8A8
uniprot id: A0A7E6D8K7
uniprot id: A0A7E6D8N9
uniprot id: A0A7E6D8R8
names: Similarity
messages: Belongs to the PROTOR family.

89673:LOC114498906
gene id: 89673:LOC114498906
uniprot id: A0A6J2LUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TAS2R1
gene id: 89673:TAS2R1
uniprot id: A0A6J2LM64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:LOC114514767
gene id: 89673:LOC114514767
uniprot id: A0A6J2NIS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

89673:LOC114490306
gene id: 89673:LOC114490306
uniprot id: A0A7E6E884
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:FAM174C
gene id: 89673:FAM174C
uniprot id: A0A6J2M993
uniprot id: A0A6J2MEK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

89673:FARSA
gene id: 89673:FARSA
uniprot id: A0A6J2MCN2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

89673:SRSF1
gene id: 89673:SRSF1
uniprot id: A0A6J2ME03
uniprot id: A0A7E6EF38
names: Similarity
messages: Belongs to the splicing factor SR family.

89673:OAZ3
gene id: 89673:OAZ3
uniprot id: A0A6J2L065
names: Similarity
messages: Belongs to the ODC antizyme family.

89673:CASP1
gene id: 89673:CASP1
uniprot id: A0A6J2M1F4
uniprot id: A0A7E6DZ80
uniprot id: A0A7E6E062
names: Similarity
messages: Belongs to the peptidase C14A family.

89673:MSH4
gene id: 89673:MSH4
uniprot id: A0A7E6DT83
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

89673:HACL1
gene id: 89673:HACL1
uniprot id: A0A6J2M429
uniprot id: A0A6J2M7G8
uniprot id: A0A7E6E4K3
names: Similarity
messages: Belongs to the TPP enzyme family.

89673:PCYT1A
gene id: 89673:PCYT1A
uniprot id: A0A6J2KYU5
uniprot id: A0A6J2L2H9
uniprot id: A0A7E6D799
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

89673:INSL6
gene id: 89673:INSL6
uniprot id: A0A6J2MB62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

89673:ZSCAN20
gene id: 89673:ZSCAN20
uniprot id: A0A6J2LJY5
uniprot id: A0A7E6DS74
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

89673:GABPA
gene id: 89673:GABPA
uniprot id: A0A6J2KV55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:LOC114500449
gene id: 89673:LOC114500449
uniprot id: A0A7E6E0Z1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:SPEN
gene id: 89673:SPEN
uniprot id: A0A6J2LJX8
names: Similarity
messages: Belongs to the RRM Spen family.

89673:SYT1
gene id: 89673:SYT1
uniprot id: A0A6J2N749
uniprot id: A0A6J2N8W7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

89673:NSDHL
gene id: 89673:NSDHL
uniprot id: A0A6J2MLK0
names: Similarity
messages: Belongs to the 3-beta-HSD family.

89673:CASP4
gene id: 89673:CASP4
uniprot id: A0A7E6DZA0
uniprot id: A0A7E6DZP3
uniprot id: A0A7E6E066
names: Similarity
messages: Belongs to the peptidase C14A family.

89673:C4BPB
gene id: 89673:C4BPB
uniprot id: A0A6J2N1T2
uniprot id: A0A7E6CWD4
uniprot id: A0A7E6CWQ3
uniprot id: A0A7E6CX34
uniprot id: A0A7E6CYY5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:PRRT2
gene id: 89673:PRRT2
uniprot id: A0A6J2L2M4
uniprot id: A0A7E6DDR5
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:TGM3
gene id: 89673:TGM3
uniprot id: A0A7E6CEW3
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

89673:NUDCD1
gene id: 89673:NUDCD1
uniprot id: A0A6J2NI68
uniprot id: A0A7E6E6P0
uniprot id: A0A7E6E8H9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:LOC114494915
gene id: 89673:LOC114494915
uniprot id: A0A6J2LG72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:GGT7
gene id: 89673:GGT7
uniprot id: A0A6J2MKB6
uniprot id: A0A6J2MPL1
uniprot id: A0A7E6CF88
uniprot id: A0A7E6CHD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

89673:PSD3
gene id: 89673:PSD3
uniprot id: A0A6J2MQ06
uniprot id: A0A7E6CKH8
names: Subcellular Location Annotation
messages: ruffle membrane

89673:BAAT
gene id: 89673:BAAT
uniprot id: A0A6J2M9C2
uniprot id: A0A7E6DFR2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

89673:SLC26A9
gene id: 89673:SLC26A9
uniprot id: A0A6J2N8N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport.
messages: Membrane

89673:RPS24
gene id: 89673:RPS24
uniprot id: A0A6J2LPS1
uniprot id: A0A6J2LQZ0
uniprot id: A0A6J2LRY7
uniprot id: A0A6J2LV87
uniprot id: A0A7E6DU17
uniprot id: A0A7E6DV64
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

89673:ZPBP2
gene id: 89673:ZPBP2
uniprot id: A0A6J2MAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted

89673:LOC114507930
gene id: 89673:LOC114507930
uniprot id: A0A7E6CH72
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

89673:AVIL
gene id: 89673:AVIL
uniprot id: A0A6J2NBE9
names: Similarity
messages: Belongs to the villin/gelsolin family.

89673:PCOLCE2
gene id: 89673:PCOLCE2
uniprot id: A0A6J2L2E6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:SLC25A36
gene id: 89673:SLC25A36
uniprot id: A0A6J2M3I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:CZIB
gene id: 89673:CZIB
uniprot id: A0A6J2LM13
uniprot id: A0A7E6DS09
names: Similarity
messages: Belongs to the UPF0587 family.

89673:LOC114503641
gene id: 89673:LOC114503641
uniprot id: A0A6J2MCS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:L3MBTL3
gene id: 89673:L3MBTL3
uniprot id: A0A6J2LBL3
uniprot id: A0A6J2LDT7
uniprot id: A0A6J2LHF5
uniprot id: A0A7E6DP53
names: Subcellular Location Annotation
messages: Nucleus

89673:PLXNA2
gene id: 89673:PLXNA2
uniprot id: A0A6J2N4E7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:PTK7
gene id: 89673:PTK7
uniprot id: A0A7E6DM14
names: Subcellular Location Annotation
messages: Membrane

89673:ZBED4
gene id: 89673:ZBED4
uniprot id: A0A6J2N8F3
names: Subcellular Location Annotation
messages: Nucleus

89673:GPR1
gene id: 89673:GPR1
uniprot id: A0A7E6DIR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

89673:ARSJ
gene id: 89673:ARSJ
uniprot id: A0A7E6E8P7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

89673:MRPS2
gene id: 89673:MRPS2
uniprot id: A0A7E6DCP8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

89673:MEGF10
gene id: 89673:MEGF10
uniprot id: A0A6J2N7C0
uniprot id: A0A7E6DBN2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TMEM131
gene id: 89673:TMEM131
uniprot id: A0A6J2M670
uniprot id: A0A7E6E4I4
names: Similarity
messages: Belongs to the TMEM131 family.

89673:LIPT2
gene id: 89673:LIPT2
uniprot id: A0A6J2LYL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Mitochondrion

89673:OSM
gene id: 89673:OSM
uniprot id: A0A7E6CRR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LIF/OSM family.
messages: Secreted

89673:PDE2A
gene id: 89673:PDE2A
uniprot id: A0A6J2LWN2
uniprot id: A0A6J2LZL1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:LOC114489017
gene id: 89673:LOC114489017
uniprot id: A0A6J2KXN3
uniprot id: A0A7E6CVI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

89673:ACVR2B
gene id: 89673:ACVR2B
uniprot id: A0A6J2M3X9
uniprot id: A0A7E6E4U9
uniprot id: A0A7E6E4Z1
uniprot id: A0A7E6E5S8
uniprot id: A0A7E6E5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

89673:ELF4
gene id: 89673:ELF4
uniprot id: A0A6J2MGJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:SET
gene id: 89673:SET
uniprot id: A0A6J2LLU4
uniprot id: A0A6J2LPK1
uniprot id: A0A7E6DGT1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

89673:LOX
gene id: 89673:LOX
uniprot id: A0A6J2MYQ1
uniprot id: A0A7E6DB45
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

89673:XYLT2
gene id: 89673:XYLT2
uniprot id: A0A6J2M704
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

89673:FAM174B
gene id: 89673:FAM174B
uniprot id: A0A7E6CPU2
uniprot id: A0A7E6CQ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

89673:LOC114508133
gene id: 89673:LOC114508133
uniprot id: A0A6J2MVR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:BARX1
gene id: 89673:BARX1
uniprot id: A0A6J2N648
names: Subcellular Location Annotation
messages: Nucleus

89673:ITGA9
gene id: 89673:ITGA9
uniprot id: A0A6J2M922
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:DEDD2
gene id: 89673:DEDD2
uniprot id: A0A6J2N2V8
names: Subcellular Location Annotation
messages: nucleolus

89673:CAPZA3
gene id: 89673:CAPZA3
uniprot id: A0A6J2NFD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

89673:TRAPPC6B
gene id: 89673:TRAPPC6B
uniprot id: A0A6J2LE39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

89673:LOC114499088
gene id: 89673:LOC114499088
uniprot id: A0A7E6E1V0
names: Subcellular Location Annotation
messages: Membrane

89673:DUSP13
gene id: 89673:DUSP13
uniprot id: A0A6J2LM10
uniprot id: A0A6J2LSF4
uniprot id: A0A7E6DTX1
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

89673:LOC114501002
gene id: 89673:LOC114501002
uniprot id: A0A6J2M1W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SHROOM4
gene id: 89673:SHROOM4
uniprot id: A0A7E6D111
uniprot id: A0A7E6D157
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

89673:PACS1
gene id: 89673:PACS1
uniprot id: A0A6J2LZ30
uniprot id: A0A7E6E2T8
names: Similarity
messages: Belongs to the PACS family.

89673:LOC114511169
gene id: 89673:LOC114511169
uniprot id: A0A6J2N607
uniprot id: A0A7E6CLP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

89673:BNIP3
gene id: 89673:BNIP3
uniprot id: A0A6J2LRC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

89673:STX12
gene id: 89673:STX12
uniprot id: A0A6J2LLT9
names: Similarity
messages: Belongs to the syntaxin family.

89673:VPS37D
gene id: 89673:VPS37D
uniprot id: A0A6J2N6T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

89673:AKR1B1
gene id: 89673:AKR1B1
uniprot id: A0A6J2MPN2
names: Similarity
messages: Belongs to the aldo/keto reductase family.

89673:MAP7D3
gene id: 89673:MAP7D3
uniprot id: A0A6J2MHD6
uniprot id: A0A7E6D1X1
names: Similarity
messages: Belongs to the MAP7 family.

89673:YKT6
gene id: 89673:YKT6
uniprot id: A0A6J2KXP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

89673:LOC114490424
gene id: 89673:LOC114490424
uniprot id: A0A6J2L1L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC12A1
gene id: 89673:SLC12A1
uniprot id: A0A6J2L8D9
uniprot id: A0A6J2LCD3
uniprot id: A0A7E6EDH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

89673:DMD
gene id: 89673:DMD
uniprot id: A0A7E6CZS6
uniprot id: A0A7E6D020
uniprot id: A0A7E6D0P5
names: Subcellular Location Annotation
messages: cytoskeleton

89673:IFT57
gene id: 89673:IFT57
uniprot id: A0A6J2L414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

89673:LOC114506533
gene id: 89673:LOC114506533
uniprot id: A0A6J2MQ15
names: Similarity
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

89673:LOC114489530
gene id: 89673:LOC114489530
uniprot id: A0A6J2KWT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:ATXN1
gene id: 89673:ATXN1
uniprot id: A0A6J2LM69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

89673:LOC114491433
gene id: 89673:LOC114491433
uniprot id: A0A7E6DMI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

89673:EEF1AKMT2
gene id: 89673:EEF1AKMT2
uniprot id: A0A6J2LNB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: Nucleus
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

89673:PSMA6
gene id: 89673:PSMA6
uniprot id: A0A6J2L922
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

89673:ADGRL1
gene id: 89673:ADGRL1
uniprot id: A0A6J2M9C4
uniprot id: A0A6J2MC52
uniprot id: A0A7E6E9D3
uniprot id: A0A7E6EA60
uniprot id: A0A7E6EAE9
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114503648
gene id: 89673:LOC114503648
uniprot id: A0A6J2MCQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC22A18
gene id: 89673:SLC22A18
uniprot id: A0A6J2M341
uniprot id: A0A7E6E2G7
names: Subcellular Location Annotation
messages: Membrane

89673:DNAH11
gene id: 89673:DNAH11
uniprot id: A0A7E6CHG0
uniprot id: A0A7E6CHQ9
uniprot id: A0A7E6CHW3
names: Similarity
messages: Belongs to the dynein heavy chain family.

89673:RIMKLB
gene id: 89673:RIMKLB
uniprot id: A0A7E6D7U9
names: Similarity
messages: Belongs to the RimK family.

89673:ANP32B
gene id: 89673:ANP32B
uniprot id: A0A6J2LMU5
names: Similarity
messages: Belongs to the ANP32 family.

89673:CTNNA1
gene id: 89673:CTNNA1
uniprot id: A0A6J2MSA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: cytoskeleton

89673:ACSS2
gene id: 89673:ACSS2
uniprot id: A0A6J2MNX9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:LOC114494052
gene id: 89673:LOC114494052
uniprot id: A0A7E6DHH9
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SETDB2
gene id: 89673:SETDB2
uniprot id: A0A6J2MR21
uniprot id: A0A7E6CK19
uniprot id: A0A7E6CK31
uniprot id: A0A7E6CK39
uniprot id: A0A7E6CK63
uniprot id: A0A7E6CM41
uniprot id: A0A7E6CM46
names: Subcellular Location Annotation
messages: Chromosome

89673:ARHGDIG
gene id: 89673:ARHGDIG
uniprot id: A0A6J2MD01
uniprot id: A0A7E6DCL8
uniprot id: A0A7E6DDP6
names: Similarity
messages: Belongs to the Rho GDI family.

89673:ADAMTS7
gene id: 89673:ADAMTS7
uniprot id: A0A6J2KUC6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:PLA2G4F
gene id: 89673:PLA2G4F
uniprot id: A0A6J2L598
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

89673:B3GAT1
gene id: 89673:B3GAT1
uniprot id: A0A6J2MWK2
uniprot id: A0A6J2MWL5
uniprot id: A0A7E6CRM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:IRF2BPL
gene id: 89673:IRF2BPL
uniprot id: A0A6J2L3Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

89673:PLCB4
gene id: 89673:PLCB4
uniprot id: A0A6J2MS30
uniprot id: A0A6J2MS35
uniprot id: A0A7E6CG79
uniprot id: A0A7E6CGJ3
uniprot id: A0A7E6CGQ9
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

89673:RUSF1
gene id: 89673:RUSF1
uniprot id: A0A6J2LQB0
uniprot id: A0A7E6DDY9
uniprot id: A0A7E6DDZ4
uniprot id: A0A7E6DE01
uniprot id: A0A7E6DE07
names: Similarity
messages: Belongs to the RUS1 family.

89673:LOC114492295
gene id: 89673:LOC114492295
uniprot id: A0A6J2L496
uniprot id: A0A7E6DE09
uniprot id: A0A7E6DE22
uniprot id: A0A7E6DE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

89673:DPH1
gene id: 89673:DPH1
uniprot id: A0A6J2M997
uniprot id: A0A7E6EG72
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.

89673:DNER
gene id: 89673:DNER
uniprot id: A0A6J2LH69
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114511583
gene id: 89673:LOC114511583
uniprot id: A0A6J2N7A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

89673:TJAP1
gene id: 89673:TJAP1
uniprot id: A0A6J2LFG9
uniprot id: A0A7E6DM16
names: Subcellular Location Annotation
messages: Membrane

89673:PROKR2
gene id: 89673:PROKR2
uniprot id: A0A6J2MN13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

89673:WASHC1
gene id: 89673:WASHC1
uniprot id: A0A7E6D560
uniprot id: A0A7E6D824
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

89673:ISCA2
gene id: 89673:ISCA2
uniprot id: A0A6J2L5L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

89673:VSTM5
gene id: 89673:VSTM5
uniprot id: A0A6J2M458
uniprot id: A0A7E6DZE1
names: Subcellular Location Annotation
messages: Membrane

89673:PLP2
gene id: 89673:PLP2
uniprot id: A0A6J2MEG2
names: Subcellular Location Annotation
messages: Membrane

89673:STK32A
gene id: 89673:STK32A
uniprot id: A0A6J2MXH3
uniprot id: A0A7E6CRZ9
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114488177
gene id: 89673:LOC114488177
uniprot id: A0A6J2KWI3
uniprot id: A0A7E6CLG9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

89673:ETV3L
gene id: 89673:ETV3L
uniprot id: A0A7E6CX97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:DNASE1L1
gene id: 89673:DNASE1L1
uniprot id: A0A6J2MLE2
uniprot id: A0A7E6D0C7
uniprot id: A0A7E6D363
names: Similarity
messages: Belongs to the DNase I family.

89673:ALKAL2
gene id: 89673:ALKAL2
uniprot id: A0A6J2M4T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

89673:KCNJ5
gene id: 89673:KCNJ5
uniprot id: A0A6J2MXA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

89673:LOC114503423
gene id: 89673:LOC114503423
uniprot id: A0A6J2MES5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

89673:EMC4
gene id: 89673:EMC4
uniprot id: A0A6J2KX92
uniprot id: A0A6J2KZI9
uniprot id: A0A6J2L177
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC4 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:SYNPR
gene id: 89673:SYNPR
uniprot id: A0A6J2M5D9
uniprot id: A0A6J2M8W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

89673:ELN
gene id: 89673:ELN
uniprot id: A0A7E6DBG8
uniprot id: A0A7E6DBH2
uniprot id: A0A7E6DBH4
uniprot id: A0A7E6DBM5
uniprot id: A0A7E6DBN0
uniprot id: A0A7E6DBN5
uniprot id: A0A7E6DBN9
uniprot id: A0A7E6DC13
uniprot id: A0A7E6DC17
uniprot id: A0A7E6DC22
uniprot id: A0A7E6DCP7
uniprot id: A0A7E6DCQ1
uniprot id: A0A7E6DCQ5
uniprot id: A0A7E6DDH6
uniprot id: A0A7E6DDH7
uniprot id: A0A7E6DDH8
uniprot id: A0A7E6DDH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elastin family.
messages: Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle.
messages: extracellular matrix

89673:LEO1
gene id: 89673:LEO1
uniprot id: A0A6J2L4F7
uniprot id: A0A6J2L8C8
names: Similarity
messages: Belongs to the LEO1 family.

89673:ABRAXAS1
gene id: 89673:ABRAXAS1
uniprot id: A0A6J2L5M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abraxas subfamily.
messages: Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
messages: Nucleus

89673:LOC114514435
gene id: 89673:LOC114514435
uniprot id: A0A7E6E882
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

89673:HCRT
gene id: 89673:HCRT
uniprot id: A0A6J2M6M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested.
messages: Rough endoplasmic reticulum
messages: Synapse
messages: Vesicle

89673:DPY30
gene id: 89673:DPY30
uniprot id: A0A6J2LVR6
names: Similarity
messages: Belongs to the dpy-30 family.

89673:TMTC1
gene id: 89673:TMTC1
uniprot id: A0A6J2N9J9
uniprot id: A0A7E6D7U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

89673:LOC114490696
gene id: 89673:LOC114490696
uniprot id: A0A7E6D5D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

89673:CCNG1
gene id: 89673:CCNG1
uniprot id: A0A6J2MWW5
uniprot id: A0A7E6CT65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin G subfamily.
messages: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
messages: Nucleus

89673:DYNC2H1
gene id: 89673:DYNC2H1
uniprot id: A0A6J2LXQ9
uniprot id: A0A6J2M384
uniprot id: A0A7E6E0I8
names: Similarity
messages: Belongs to the dynein heavy chain family.

89673:CDKN1C
gene id: 89673:CDKN1C
uniprot id: A0A6J2LZR7
uniprot id: A0A7E6E3Z5
names: Similarity
messages: Belongs to the CDI family.

89673:SFTPD
gene id: 89673:SFTPD
uniprot id: A0A7E6DTU8
uniprot id: A0A7E6DU02
uniprot id: A0A7E6DUG7
uniprot id: A0A7E6DUT4
uniprot id: A0A7E6DV49
names: Similarity
names: Subunit
messages: Belongs to the SFTPD family.
messages: Oligomeric complex of 4 set of homotrimers.

89673:FGFR1OP2
gene id: 89673:FGFR1OP2
uniprot id: A0A6J2N9S3
uniprot id: A0A6J2NEH2
names: Similarity
messages: Belongs to the SIKE family.

89673:SH3GL3
gene id: 89673:SH3GL3
uniprot id: A0A7E6CQ18
uniprot id: A0A7E6CSJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Implicated in endocytosis. May recruit other proteins to membranes with high curvature.
messages: Membrane

89673:AARSD1
gene id: 89673:AARSD1
uniprot id: A0A6J2MEI3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

89673:LOC114503644
gene id: 89673:LOC114503644
uniprot id: A0A6J2MAK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DBH
gene id: 89673:DBH
uniprot id: A0A6J2MSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Conversion of dopamine to noradrenaline.
messages: Homotetramer; composed of two disulfide-linked dimers.
messages: chromaffin granule lumen
messages: chromaffin granule membrane
messages: secretory vesicle lumen
messages: secretory vesicle membrane

89673:DPT
gene id: 89673:DPT
uniprot id: A0A6J2N2H5
names: Similarity
messages: Belongs to the dermatopontin family.

89673:KCNA3
gene id: 89673:KCNA3
uniprot id: A0A6J2KWI6
names: Subcellular Location Annotation
messages: Membrane

89673:MRPL3
gene id: 89673:MRPL3
uniprot id: A0A6J2M3P5
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

89673:SARM1
gene id: 89673:SARM1
uniprot id: A0A6J2M9H5
uniprot id: A0A7E6EE59
names: Similarity
messages: Belongs to the SARM1 family.

89673:ERFL
gene id: 89673:ERFL
uniprot id: A0A6J2N7H7
uniprot id: A0A7E6CP59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:COQ2
gene id: 89673:COQ2
uniprot id: A0A6J2L8L6
uniprot id: A0A7E6DVZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

89673:FAT1
gene id: 89673:FAT1
uniprot id: A0A6J2MQ22
uniprot id: A0A7E6CL32
uniprot id: A0A7E6CL38
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:PODXL
gene id: 89673:PODXL
uniprot id: A0A6J2MSV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the podocalyxin family.
messages: Cell membrane
messages: Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.
messages: Membrane
messages: Membrane raft
messages: filopodium
messages: lamellipodium
messages: microvillus
messages: ruffle

89673:STAG2
gene id: 89673:STAG2
uniprot id: A0A6J2MDM3
uniprot id: A0A6J2MFR6
uniprot id: A0A6J2MJN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

89673:LOC114499056
gene id: 89673:LOC114499056
uniprot id: A0A6J2LYB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TMOD2
gene id: 89673:TMOD2
uniprot id: A0A6J2L801
names: Subcellular Location Annotation
messages: cytoskeleton

89673:ADCK1
gene id: 89673:ADCK1
uniprot id: A0A6J2L6T1
uniprot id: A0A7E6CRC3
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

89673:SGO2
gene id: 89673:SGO2
uniprot id: A0A6J2LDQ2
uniprot id: A0A6J2LEW9
uniprot id: A0A7E6DJ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

89673:GTF2A2
gene id: 89673:GTF2A2
uniprot id: A0A6J2L8Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

89673:LOC114509275
gene id: 89673:LOC114509275
uniprot id: A0A6J2MUY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

89673:GABBR2
gene id: 89673:GABBR2
uniprot id: A0A6J2N700
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

89673:TEC
gene id: 89673:TEC
uniprot id: A0A6J2LDV4
uniprot id: A0A7E6DAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:HOMER2
gene id: 89673:HOMER2
uniprot id: A0A6J2KTR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

89673:PCSK6
gene id: 89673:PCSK6
uniprot id: A0A7E6CPE9
names: Similarity
messages: Belongs to the peptidase S8 family.

89673:LOC114490147
gene id: 89673:LOC114490147
uniprot id: A0A6J2KZ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

89673:LOC114499602
gene id: 89673:LOC114499602
uniprot id: A0A6J2LWK2
uniprot id: A0A7E6DYU6
names: Similarity
messages: Belongs to the peptidase M67C family.

89673:SLC17A9
gene id: 89673:SLC17A9
uniprot id: A0A6J2MQP2
names: Subcellular Location Annotation
messages: Membrane

89673:FIBIN
gene id: 89673:FIBIN
uniprot id: A0A6J2M183
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FIBIN family.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer; disulfide-linked. Seems to also exist as monomers.
messages: Secreted

89673:AASDH
gene id: 89673:AASDH
uniprot id: A0A7E6DBM2
uniprot id: A0A7E6DC82
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:HAUS3
gene id: 89673:HAUS3
uniprot id: A0A6J2L1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

89673:HAPLN4
gene id: 89673:HAPLN4
uniprot id: A0A6J2M900
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:AMER3
gene id: 89673:AMER3
uniprot id: A0A6J2MVZ1
names: Similarity
messages: Belongs to the Amer family.

89673:INPP4A
gene id: 89673:INPP4A
uniprot id: A0A6J2LTH1
uniprot id: A0A7E6E318
uniprot id: A0A7E6E323
uniprot id: A0A7E6E328
uniprot id: A0A7E6E3M7
uniprot id: A0A7E6E3N1
uniprot id: A0A7E6E3N6
uniprot id: A0A7E6E3R5
uniprot id: A0A7E6E3S0
uniprot id: A0A7E6E4I9
uniprot id: A0A7E6E4J4
uniprot id: A0A7E6E4J8
uniprot id: A0A7E6E4P5
uniprot id: A0A7E6E4P9
uniprot id: A0A7E6E4Q4
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

89673:ALG2
gene id: 89673:ALG2
uniprot id: A0A6J2LUK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

89673:ALDH4A1
gene id: 89673:ALDH4A1
uniprot id: A0A6J2LP50
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

89673:LOC114504605
gene id: 89673:LOC114504605
uniprot id: A0A6J2MJI6
names: Similarity
messages: Belongs to the FAM47 family.

89673:LOC114503653
gene id: 89673:LOC114503653
uniprot id: A0A7E6E971
names: Subcellular Location Annotation
messages: Secreted

89673:ACADVL
gene id: 89673:ACADVL
uniprot id: A0A6J2NDX5
uniprot id: A0A6J2NIL0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

89673:RELL1
gene id: 89673:RELL1
uniprot id: A0A6J2LE34
names: Similarity
messages: Belongs to the RELT family.

89673:LOC114488309
gene id: 89673:LOC114488309
uniprot id: A0A7E6CN08
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

89673:OLFML3
gene id: 89673:OLFML3
uniprot id: A0A6J2KZ73
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OLFML3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:LOC114493134
gene id: 89673:LOC114493134
uniprot id: A0A6J2L7K6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

89673:SLC6A20
gene id: 89673:SLC6A20
uniprot id: A0A6J2M7W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

89673:CHIT1
gene id: 89673:CHIT1
uniprot id: A0A6J2NJL4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

89673:MMP2
gene id: 89673:MMP2
uniprot id: A0A6J2KRE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M10A family.
messages: Interacts (via the C-terminal hemopexin-like domains-containing region) with the integrin alpha-V/beta-3; the interaction promotes vascular invasion in angiogenic vessels and melamoma cells. Interacts (via the C-terminal PEX domain) with TIMP2 (via the C-terminal); the interaction inhibits the degradation activity. Interacts with GSK3B.
messages: extracellular matrix

89673:TMCO1
gene id: 89673:TMCO1
uniprot id: A0A6J2N9G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer and homotetramer. Homodimer under resting conditions; forms homotetramers following and ER calcium overload.
messages: Membrane

89673:ALCAM
gene id: 89673:ALCAM
uniprot id: A0A6J2KUP6
uniprot id: A0A6J2KYI0
names: Subcellular Location Annotation
messages: Cell membrane
messages: axon
messages: dendrite

89673:NCAN
gene id: 89673:NCAN
uniprot id: A0A7E6EAY7
uniprot id: A0A7E6EC75
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:SLC18B1
gene id: 89673:SLC18B1
uniprot id: A0A6J2LC94
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114512462
gene id: 89673:LOC114512462
uniprot id: A0A7E6D0T3
names: Similarity
messages: Belongs to the peptidase C2 family.

89673:LOC114500595
gene id: 89673:LOC114500595
uniprot id: A0A6J2M0L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:YY1
gene id: 89673:YY1
uniprot id: A0A6J2L210
names: Similarity
messages: Belongs to the YY transcription factor family.

89673:MTMR2
gene id: 89673:MTMR2
uniprot id: A0A6J2M085
uniprot id: A0A6J2M1H5
uniprot id: A0A7E6DZC9
uniprot id: A0A7E6DZS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

89673:RCAN1
gene id: 89673:RCAN1
uniprot id: A0A6J2KYQ8
uniprot id: A0A6J2L0C1
names: Similarity
messages: Belongs to the RCAN family.

89673:APTX
gene id: 89673:APTX
uniprot id: A0A6J2MRY7
uniprot id: A0A6J2MY94
uniprot id: A0A7E6DFC4
names: Subcellular Location Annotation
messages: nucleolus
messages: nucleoplasm

89673:SUSD5
gene id: 89673:SUSD5
uniprot id: A0A6J2M5B8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114490204
gene id: 89673:LOC114490204
uniprot id: A0A6J2KXI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:IK
gene id: 89673:IK
uniprot id: A0A6J2N018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RED family.
messages: Nucleus

89673:CHD7
gene id: 89673:CHD7
uniprot id: A0A6J2NBL4
uniprot id: A0A7E6E6L5
uniprot id: A0A7E6E6Y3
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

89673:IP6K3
gene id: 89673:IP6K3
uniprot id: A0A6J2LG06
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

89673:ARMC8
gene id: 89673:ARMC8
uniprot id: A0A6J2M3R1
uniprot id: A0A6J2M5D7
uniprot id: A0A7E6E4S3
uniprot id: A0A7E6E5E5
uniprot id: A0A7E6E5I2
uniprot id: A0A7E6E6D0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:MPP5
gene id: 89673:MPP5
uniprot id: A0A6J2L4F2
uniprot id: A0A6J2L6H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Endomembrane system
messages: tight junction

89673:LOC114505957
gene id: 89673:LOC114505957
uniprot id: A0A7E6CID2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Induces an itch response through activation of receptors present on mast cells, triggering mast cell degranulation.
messages: Secreted
messages: neuron projection
messages: secretory vesicle lumen

89673:FAM199X
gene id: 89673:FAM199X
uniprot id: A0A6J2MFJ7
names: Similarity
messages: Belongs to the FAM199 family.

89673:SDF4
gene id: 89673:SDF4
uniprot id: A0A6J2LQC2
uniprot id: A0A6J2LTH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

89673:CLPS
gene id: 89673:CLPS
uniprot id: A0A6J2LM68
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

89673:LOC114505656
gene id: 89673:LOC114505656
uniprot id: A0A7E6D3C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

89673:LOC114500022
gene id: 89673:LOC114500022
uniprot id: A0A6J2M2F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TRIM9
gene id: 89673:TRIM9
uniprot id: A0A6J2L7W2
uniprot id: A0A6J2L8E7
uniprot id: A0A6J2LCL6
uniprot id: A0A6J2LDM7
uniprot id: A0A7E6CG07
uniprot id: A0A7E6CG52
uniprot id: A0A7E6CG81
uniprot id: A0A7E6CGF4
uniprot id: A0A7E6CI12
uniprot id: A0A7E6CI21
uniprot id: A0A7E6CI26
names: Subcellular Location Annotation
messages: Cytoplasm
messages: cytoskeleton

89673:ATP11C
gene id: 89673:ATP11C
uniprot id: A0A7E6CYK6
uniprot id: A0A7E6CYL1
uniprot id: A0A7E6CYQ9
uniprot id: A0A7E6CZ22
uniprot id: A0A7E6CZ28
uniprot id: A0A7E6CZJ2
uniprot id: A0A7E6CZJ7
uniprot id: A0A7E6D185
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC118498209
gene id: 89673:LOC118498209
uniprot id: A0A6J2KUL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:ROR2
gene id: 89673:ROR2
uniprot id: A0A6J2NBD1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:COPS5
gene id: 89673:COPS5
uniprot id: A0A6J2NAG0
uniprot id: A0A6J2NC36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

89673:SVIL
gene id: 89673:SVIL
uniprot id: A0A6J2LEC7
uniprot id: A0A7E6DHT4
uniprot id: A0A7E6DHX1
uniprot id: A0A7E6DHY2
uniprot id: A0A7E6DHY9
uniprot id: A0A7E6DHZ8
uniprot id: A0A7E6DI09
uniprot id: A0A7E6DI35
names: Similarity
messages: Belongs to the villin/gelsolin family.

89673:LOC114512605
gene id: 89673:LOC114512605
uniprot id: A0A6J2N6A1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114499225
gene id: 89673:LOC114499225
uniprot id: A0A6J2LTC4
uniprot id: A0A6J2LUI7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with RET in the pituitary gland; this interaction prevents the formation of the AIP-survivin complex.
messages: May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.

89673:SLC13A3
gene id: 89673:SLC13A3
uniprot id: A0A6J2MQE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

89673:PTMS
gene id: 89673:PTMS
uniprot id: A0A6J2N964
names: Similarity
messages: Belongs to the pro/parathymosin family.

89673:POLRMT
gene id: 89673:POLRMT
uniprot id: A0A6J2M9B3
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

89673:SGSM1
gene id: 89673:SGSM1
uniprot id: A0A6J2N2C5
uniprot id: A0A7E6CUF3
uniprot id: A0A7E6CV88
uniprot id: A0A7E6CX84
names: Similarity
messages: Belongs to the RUTBC family.

89673:LOC114510993
gene id: 89673:LOC114510993
uniprot id: A0A7E6DA35
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:MMP7
gene id: 89673:MMP7
uniprot id: A0A6J2LXM5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Binds 2 calcium ions per subunit.

89673:STAM2
gene id: 89673:STAM2
uniprot id: A0A6J2LD05
uniprot id: A0A6J2LDZ9
uniprot id: A0A6J2LHT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

89673:SPNS3
gene id: 89673:SPNS3
uniprot id: A0A6J2NCI9
uniprot id: A0A7E6EBZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

89673:TSC22D3
gene id: 89673:TSC22D3
uniprot id: A0A6J2MII7
uniprot id: A0A6J2MN02
uniprot id: A0A7E6D0M5
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

89673:PARD6G
gene id: 89673:PARD6G
uniprot id: A0A6J2MKJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

89673:GAD2
gene id: 89673:GAD2
uniprot id: A0A7E6DJ39
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

89673:LOC114512581
gene id: 89673:LOC114512581
uniprot id: A0A6J2N493
uniprot id: A0A7E6DE06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Membrane
messages: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

89673:LOC114498815
gene id: 89673:LOC114498815
uniprot id: A0A6J2LTL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

89673:SPTB
gene id: 89673:SPTB
uniprot id: A0A6J2L6D4
names: Similarity
messages: Belongs to the spectrin family.

89673:RNF43
gene id: 89673:RNF43
uniprot id: A0A6J2M9D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

89673:SLITRK4
gene id: 89673:SLITRK4
uniprot id: A0A6J2ML34
names: Similarity
messages: Belongs to the SLITRK family.

89673:LOC114507832
gene id: 89673:LOC114507832
uniprot id: A0A6J2MQ73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114509173
gene id: 89673:LOC114509173
uniprot id: A0A6J2MU99
uniprot id: A0A7E6CV03
uniprot id: A0A7E6CVA1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

89673:TTR
gene id: 89673:TTR
uniprot id: A0A6J2MQX1
uniprot id: A0A6J2MQZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer. Dimer of dimers. In the homotetramer, subunits assemble around a central channel that can accommodate two ligand molecules. Interacts with RBP4.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

89673:LOC114490268
gene id: 89673:LOC114490268
uniprot id: A0A6J2L302
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114502621
gene id: 89673:LOC114502621
uniprot id: A0A6J2M7N1
uniprot id: A0A6J2MAX2
uniprot id: A0A7E6EBC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GIPC family.
messages: Cell membrane
messages: Membrane

89673:BET1L
gene id: 89673:BET1L
uniprot id: A0A6J2LY49
uniprot id: A0A7E6E3F8
uniprot id: A0A7E6E467
names: Subcellular Location Annotation
messages: Membrane

89673:TRHDE
gene id: 89673:TRHDE
uniprot id: A0A6J2NDF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Membrane

89673:SNCB
gene id: 89673:SNCB
uniprot id: A0A6J2N1U2
names: Similarity
messages: Belongs to the synuclein family.

89673:LOC114489983
gene id: 89673:LOC114489983
uniprot id: A0A6J2KW87
names: Similarity
messages: Belongs to the actin family.

89673:KIF13A
gene id: 89673:KIF13A
uniprot id: A0A7E6DT40
uniprot id: A0A7E6DT44
uniprot id: A0A7E6DT77
uniprot id: A0A7E6DTP1
uniprot id: A0A7E6DTP9
uniprot id: A0A7E6DTW0
uniprot id: A0A7E6DTW5
uniprot id: A0A7E6DUA8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:LEAP2
gene id: 89673:LEAP2
uniprot id: A0A6J2N3P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

89673:LOC114510217
gene id: 89673:LOC114510217
uniprot id: A0A6J2MYL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NOP10
gene id: 89673:NOP10
uniprot id: A0A6J2L327
names: Similarity
messages: Belongs to the NOP10 family.

89673:KCTD13
gene id: 89673:KCTD13
uniprot id: A0A6J2LDM0
names: Similarity
messages: Belongs to the BACURD family.

89673:UBA2
gene id: 89673:UBA2
uniprot id: A0A6J2MYF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

89673:SARS1
gene id: 89673:SARS1
uniprot id: A0A6J2KZC6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

89673:LOC114492382
gene id: 89673:LOC114492382
uniprot id: A0A7E6CTC5
names: Subcellular Location Annotation
messages: Nucleus

89673:CTNND1
gene id: 89673:CTNND1
uniprot id: A0A6J2LS26
uniprot id: A0A6J2LTE0
uniprot id: A0A7E6E1E2
uniprot id: A0A7E6E1X5
uniprot id: A0A7E6E1X9
uniprot id: A0A7E6E2T0
uniprot id: A0A7E6E2U3
names: Similarity
messages: Belongs to the beta-catenin family.

89673:LOC114496646
gene id: 89673:LOC114496646
uniprot id: A0A6J2LL77
uniprot id: A0A7E6DRW2
uniprot id: A0A7E6DSJ4
uniprot id: A0A7E6DSN1
uniprot id: A0A7E6DT21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

89673:MRPL18
gene id: 89673:MRPL18
uniprot id: A0A6J2LF81
names: Similarity
messages: Belongs to the universal ribosomal protein uL18 family.

89673:ACTL6B
gene id: 89673:ACTL6B
uniprot id: A0A6J2M4F1
uniprot id: A0A7E6DBU9
uniprot id: A0A7E6DCI7
names: Similarity
messages: Belongs to the actin family.

89673:ACADSB
gene id: 89673:ACADSB
uniprot id: A0A6J2LRT4
uniprot id: A0A7E6DVX7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

89673:AMACR
gene id: 89673:AMACR
uniprot id: A0A6J2MWS2
names: Similarity
messages: Belongs to the CoA-transferase III family.

89673:ADGRE5
gene id: 89673:ADGRE5
uniprot id: A0A7E6EA48
uniprot id: A0A7E6EAD5
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:DEFB124
gene id: 89673:DEFB124
uniprot id: A0A6J2MJ68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

89673:SEC61B
gene id: 89673:SEC61B
uniprot id: A0A6J2M9B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

89673:GHRL
gene id: 89673:GHRL
uniprot id: A0A6J2M3N3
uniprot id: A0A7E6E549
uniprot id: A0A7E6E6N7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
messages: O-octanoylation is essential for ghrelin activity.
messages: Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.
messages: Secreted

89673:FAM151A
gene id: 89673:FAM151A
uniprot id: A0A7E6DSU1
uniprot id: A0A7E6DTB8
names: Similarity
messages: Belongs to the FAM151 family.

89673:ITIH4
gene id: 89673:ITIH4
uniprot id: A0A6J2M7V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

89673:ACTC1
gene id: 89673:ACTC1
uniprot id: A0A6J2L3S1
names: Similarity
messages: Belongs to the actin family.

89673:KREMEN2
gene id: 89673:KREMEN2
uniprot id: A0A6J2LF96
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.

89673:LOC114498873
gene id: 89673:LOC114498873
uniprot id: A0A7E6E024
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SNX10
gene id: 89673:SNX10
uniprot id: A0A6J2MTZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

89673:NDUFV1
gene id: 89673:NDUFV1
uniprot id: A0A6J2LY92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

89673:HUS1B
gene id: 89673:HUS1B
uniprot id: A0A7E6DUQ5
names: Similarity
messages: Belongs to the HUS1 family.

89673:SLC1A4
gene id: 89673:SLC1A4
uniprot id: A0A6J2LX75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

89673:NUP133
gene id: 89673:NUP133
uniprot id: A0A6J2N517
uniprot id: A0A7E6CYC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

89673:DCPS
gene id: 89673:DCPS
uniprot id: A0A6J2MWC2
uniprot id: A0A7E6CTV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HIT family.
messages: Cytoplasm
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.
messages: Nucleus

89673:PPARGC1A
gene id: 89673:PPARGC1A
uniprot id: A0A6J2L166
uniprot id: A0A6J2L1X7
uniprot id: A0A6J2L5H5
uniprot id: A0A7E6D7N8
uniprot id: A0A7E6D7P2
names: Subcellular Location Annotation
messages: PML body

89673:LOC114512326
gene id: 89673:LOC114512326
uniprot id: A0A6J2N5D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CGA
gene id: 89673:CGA
uniprot id: A0A6J2LIW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer. The active hormones thyrotropin, lutropin and follitropin are heterodimers composed of CGA, a common alpha chain described here and a unique beta chain which confers their biological specificity to the hormones: TSHB for thyrotropin, LHB for lutropin and FSHB for follitropin.
messages: Secreted
messages: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.

89673:ARGLU1
gene id: 89673:ARGLU1
uniprot id: A0A6J2MXI2
names: Similarity
messages: Belongs to the UPF0430 family.

89673:LOC114493964
gene id: 89673:LOC114493964
uniprot id: A0A7E6DIW0
names: Similarity
messages: Belongs to the NAC-beta family.

89673:TDGF1
gene id: 89673:TDGF1
uniprot id: A0A6J2M4G3
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LYN
gene id: 89673:LYN
uniprot id: A0A6J2NHY6
uniprot id: A0A7E6E7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:RBBP8
gene id: 89673:RBBP8
uniprot id: A0A6J2MQ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

89673:LOC114500170
gene id: 89673:LOC114500170
uniprot id: A0A6J2LXX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:EML1
gene id: 89673:EML1
uniprot id: A0A6J2L3L3
uniprot id: A0A6J2L491
uniprot id: A0A7E6CS43
uniprot id: A0A7E6CS44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EMAP family.
messages: cytoskeleton

89673:PDK2
gene id: 89673:PDK2
uniprot id: A0A6J2MD51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

89673:MMP25
gene id: 89673:MMP25
uniprot id: A0A6J2N0P9
names: Similarity
messages: Belongs to the peptidase M10A family.

89673:GBE1
gene id: 89673:GBE1
uniprot id: A0A7E6D472
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

89673:GBX2
gene id: 89673:GBX2
uniprot id: A0A6J2LFC9
uniprot id: A0A6J2LK44
names: Subcellular Location Annotation
messages: Nucleus

89673:UBR4
gene id: 89673:UBR4
uniprot id: A0A6J2LL29
uniprot id: A0A7E6DQ25
uniprot id: A0A7E6DQ42
uniprot id: A0A7E6DQT5
uniprot id: A0A7E6DR88
names: Similarity
messages: Belongs to the UBR4 family.

89673:ANXA9
gene id: 89673:ANXA9
uniprot id: A0A6J2KW43
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

89673:LOC114511296
gene id: 89673:LOC114511296
uniprot id: A0A7E6CRD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

89673:LOC114500426
gene id: 89673:LOC114500426
uniprot id: A0A6J2M0X2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ADAM28
gene id: 89673:ADAM28
uniprot id: A0A7E6EAB7
uniprot id: A0A7E6EAC0
uniprot id: A0A7E6EB38
uniprot id: A0A7E6EB43
uniprot id: A0A7E6EB95
uniprot id: A0A7E6EBX2
uniprot id: A0A7E6EBX5
uniprot id: A0A7E6ECB9
uniprot id: A0A7E6ECC3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TRAF4
gene id: 89673:TRAF4
uniprot id: A0A6J2MDW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

89673:LIPC
gene id: 89673:LIPC
uniprot id: A0A6J2L9V9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:RAB4A
gene id: 89673:RAB4A
uniprot id: A0A6J2N541
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

89673:LOC114492009
gene id: 89673:LOC114492009
uniprot id: A0A7E6CMS8
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:LOC114506699
gene id: 89673:LOC114506699
uniprot id: A0A6J2MQR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Endoplasmic reticulum
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Kunitz-type serine protease inhibitor. Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation. Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer. Also occurs as a complex with tryptase in mast cells.
messages: Nucleus membrane
messages: cytosol
messages: extracellular matrix

89673:NSMCE1
gene id: 89673:NSMCE1
uniprot id: A0A6J2MV02
uniprot id: A0A7E6DE05
uniprot id: A0A7E6DE31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus
messages: RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Involved in maintenance of genome integrity, DNA damage response and DNA repair.
messages: telomere

89673:LOC114502930
gene id: 89673:LOC114502930
uniprot id: A0A6J2MCY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:SMIM5
gene id: 89673:SMIM5
uniprot id: A0A7E6EEL2
names: Subcellular Location Annotation
messages: Membrane

89673:TYMS
gene id: 89673:TYMS
uniprot id: A0A6J2MIY6
uniprot id: A0A6J2ML54
names: Similarity
messages: Belongs to the thymidylate synthase family.

89673:ECH1
gene id: 89673:ECH1
uniprot id: A0A6J2N600
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

89673:NEURL2
gene id: 89673:NEURL2
uniprot id: A0A6J2MLE5
names: Subcellular Location Annotation
messages: Cytoplasm

89673:LOC114493937
gene id: 89673:LOC114493937
uniprot id: A0A6J2LEM9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

89673:LOC114505076
gene id: 89673:LOC114505076
uniprot id: A0A7E6CYT1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:UBA5
gene id: 89673:UBA5
uniprot id: A0A7E6E688
uniprot id: A0A7E6E6D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus

89673:DNMT3B
gene id: 89673:DNMT3B
uniprot id: A0A6J2MM51
uniprot id: A0A7E6CF34
uniprot id: A0A7E6CF86
uniprot id: A0A7E6CF92
uniprot id: A0A7E6CFQ3
uniprot id: A0A7E6CH96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

89673:LOC114499905
gene id: 89673:LOC114499905
uniprot id: A0A6J2LWW9
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:WHAMM
gene id: 89673:WHAMM
uniprot id: A0A7E6CQ05
names: Subcellular Location Annotation
messages: Membrane

89673:SLC7A10
gene id: 89673:SLC7A10
uniprot id: A0A6J2N628
names: Subcellular Location Annotation
messages: Membrane

89673:GRHL3
gene id: 89673:GRHL3
uniprot id: A0A6J2LS23
names: Subcellular Location Annotation
messages: Nucleus

89673:UBALD2
gene id: 89673:UBALD2
uniprot id: A0A6J2MCM0
names: Similarity
messages: Belongs to the UBALD family.

89673:KIAA1191
gene id: 89673:KIAA1191
uniprot id: A0A6J2MV46
uniprot id: A0A6J2MZQ5
uniprot id: A0A7E6CUK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P33MONOX family.
messages: Cytoplasm
messages: Interacts with NELFB, NOL12 and PRNP.
messages: Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.

89673:SLCO6A1
gene id: 89673:SLCO6A1
uniprot id: A0A6J2LFN9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:KCNC2
gene id: 89673:KCNC2
uniprot id: A0A6J2NB43
uniprot id: A0A6J2NBH0
uniprot id: A0A7E6D5M1
uniprot id: A0A7E6D5P2
uniprot id: A0A7E6D5P7
uniprot id: A0A7E6D5R2
uniprot id: A0A7E6D6A7
uniprot id: A0A7E6D8G1
uniprot id: A0A7E6D8G8
names: Subcellular Location Annotation
messages: Membrane

89673:FBLN2
gene id: 89673:FBLN2
uniprot id: A0A6J2KYK8
uniprot id: A0A6J2L3S2
uniprot id: A0A7E6D4N4
uniprot id: A0A7E6D4R9
uniprot id: A0A7E6D7E2
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RPL18
gene id: 89673:RPL18
uniprot id: A0A6J2N5V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Rough endoplasmic reticulum

89673:LOC114489384
gene id: 89673:LOC114489384
uniprot id: A0A6J2KUR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

89673:AMPD3
gene id: 89673:AMPD3
uniprot id: A0A6J2LWD3
uniprot id: A0A7E6E0A1
uniprot id: A0A7E6E0G2
uniprot id: A0A7E6E0G8
uniprot id: A0A7E6E0T6
uniprot id: A0A7E6E1I8
uniprot id: A0A7E6E1J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

89673:NPM3
gene id: 89673:NPM3
uniprot id: A0A6J2LNS0
names: Similarity
messages: Belongs to the nucleoplasmin family.

89673:SETD6
gene id: 89673:SETD6
uniprot id: A0A7E6CLL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: Protein-lysine N-methyltransferase.

89673:RPS14
gene id: 89673:RPS14
uniprot id: A0A6J2N0F4
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

89673:KAT6B
gene id: 89673:KAT6B
uniprot id: A0A7E6DWY1
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

89673:SCARB1
gene id: 89673:SCARB1
uniprot id: A0A6J2MWQ9
uniprot id: A0A7E6CUX4
names: Similarity
messages: Belongs to the CD36 family.

89673:CNOT6L
gene id: 89673:CNOT6L
uniprot id: A0A6J2L5N6
uniprot id: A0A6J2LAY0
uniprot id: A0A7E6DHF7
uniprot id: A0A7E6DHK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

89673:NR5A2
gene id: 89673:NR5A2
uniprot id: A0A6J2NAB0
uniprot id: A0A7E6CY36
uniprot id: A0A7E6CYJ9
uniprot id: A0A7E6CZ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

89673:DARS2
gene id: 89673:DARS2
uniprot id: A0A6J2N3Y2
uniprot id: A0A7E6CXU0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

89673:EMC3
gene id: 89673:EMC3
uniprot id: A0A6J2M833
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

89673:UBL4A
gene id: 89673:UBL4A
uniprot id: A0A6J2MHQ9
names: Subcellular Location Annotation
messages: cytosol

89673:POC5
gene id: 89673:POC5
uniprot id: A0A7E6DAG8
uniprot id: A0A7E6DAK1
uniprot id: A0A7E6DD67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

89673:CPOX
gene id: 89673:CPOX
uniprot id: A0A6J2L4A4
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

89673:LOC114504811
gene id: 89673:LOC114504811
uniprot id: A0A7E6D2M3
names: Similarity
messages: Belongs to the TMA7 family.

89673:LOC114488317
gene id: 89673:LOC114488317
uniprot id: A0A6J2KX36
names: Subcellular Location Annotation
messages: Membrane

89673:TYRO3
gene id: 89673:TYRO3
uniprot id: A0A6J2LE80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

89673:CEP20
gene id: 89673:CEP20
uniprot id: A0A6J2MD20
uniprot id: A0A6J2MD25
uniprot id: A0A7E6DBN1
uniprot id: A0A7E6DBV7
uniprot id: A0A7E6DCV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: centriole
messages: cilium basal body

89673:ENO4
gene id: 89673:ENO4
uniprot id: A0A6J2LNP2
names: Similarity
messages: Belongs to the enolase family.

89673:CHD3
gene id: 89673:CHD3
uniprot id: A0A6J2NJT1
uniprot id: A0A7E6EBE1
uniprot id: A0A7E6EBE6
uniprot id: A0A7E6EBF6
uniprot id: A0A7E6EC52
uniprot id: A0A7E6EC55
uniprot id: A0A7E6EC64
uniprot id: A0A7E6EC74
uniprot id: A0A7E6EC78
uniprot id: A0A7E6EC83
uniprot id: A0A7E6EC89
uniprot id: A0A7E6ED15
uniprot id: A0A7E6ED21
uniprot id: A0A7E6ED27
uniprot id: A0A7E6ED99
uniprot id: A0A7E6EDB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

89673:LOC114508473
gene id: 89673:LOC114508473
uniprot id: A0A6J2MWF1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:USP4
gene id: 89673:USP4
uniprot id: A0A6J2M509
uniprot id: A0A6J2M7U6
uniprot id: A0A7E6E3U2
uniprot id: A0A7E6E5G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

89673:COQ8A
gene id: 89673:COQ8A
uniprot id: A0A6J2N5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane
messages: Mitochondrion

89673:PDCD5
gene id: 89673:PDCD5
uniprot id: A0A6J2NFJ2
uniprot id: A0A7E6CN06
uniprot id: A0A7E6CN13
uniprot id: A0A7E6CN57
uniprot id: A0A7E6CQE9
names: Similarity
messages: Belongs to the PDCD5 family.

89673:COPS6
gene id: 89673:COPS6
uniprot id: A0A6J2MNQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN6 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.
messages: Cytoplasm
messages: Nucleus

89673:SPPL2A
gene id: 89673:SPPL2A
uniprot id: A0A7E6EE63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

89673:FAM168A
gene id: 89673:FAM168A
uniprot id: A0A6J2LVM5
uniprot id: A0A6J2M0L4
uniprot id: A0A6J2M136
uniprot id: A0A7E6DZU6
names: Similarity
messages: Belongs to the FAM168 family.

89673:LOC114495152
gene id: 89673:LOC114495152
uniprot id: A0A6J2LK00
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:TAFA1
gene id: 89673:TAFA1
uniprot id: A0A6J2M3H3
names: Similarity
messages: Belongs to the TAFA family.

89673:LOC114504872
gene id: 89673:LOC114504872
uniprot id: A0A7E6CZM7
names: Subcellular Location Annotation
messages: Membrane

89673:GUCA2B
gene id: 89673:GUCA2B
uniprot id: A0A6J2LN97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

89673:TMEM131L
gene id: 89673:TMEM131L
uniprot id: A0A6J2M8K5
names: Similarity
messages: Belongs to the TMEM131 family.

89673:LOC114500490
gene id: 89673:LOC114500490
uniprot id: A0A6J2M4L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:BMP8A
gene id: 89673:BMP8A
uniprot id: A0A6J2LSQ8
names: Similarity
messages: Belongs to the TGF-beta family.

89673:C5H1orf174
gene id: 89673:C5H1orf174
uniprot id: A0A6J2LRD5
uniprot id: A0A7E6DQ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

89673:CDH7
gene id: 89673:CDH7
uniprot id: A0A6J2MKV4
uniprot id: A0A7E6CGX0
uniprot id: A0A7E6CIL2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:LCK
gene id: 89673:LCK
uniprot id: A0A6J2LTN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

89673:ABITRAM
gene id: 89673:ABITRAM
uniprot id: A0A6J2M6X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

89673:IQSEC3
gene id: 89673:IQSEC3
uniprot id: A0A6J2N7X0
uniprot id: A0A6J2NEP8
uniprot id: A0A7E6D555
uniprot id: A0A7E6D577
names: Similarity
messages: Belongs to the BRAG family.

89673:LOC114505201
gene id: 89673:LOC114505201
uniprot id: A0A7E6D235
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:CA5B
gene id: 89673:CA5B
uniprot id: A0A6J2MLY4
uniprot id: A0A7E6D3F9
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

89673:FXYD6
gene id: 89673:FXYD6
uniprot id: A0A6J2M0R0
uniprot id: A0A6J2M463
uniprot id: A0A7E6DYX9
uniprot id: A0A7E6E073
names: Similarity
messages: Belongs to the FXYD family.

89673:LOC114490342
gene id: 89673:LOC114490342
uniprot id: A0A6J2L1F2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114504063
gene id: 89673:LOC114504063
uniprot id: A0A6J2MHQ4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114490189
gene id: 89673:LOC114490189
uniprot id: A0A6J2KXH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PRICKLE3
gene id: 89673:PRICKLE3
uniprot id: A0A6J2MFD5
uniprot id: A0A7E6D1Q0
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

89673:LOC114493891
gene id: 89673:LOC114493891
uniprot id: A0A6J2LFH2
uniprot id: A0A7E6DKW1
uniprot id: A0A7E6DL91
names: Similarity
names: Subunit
messages: Belongs to the TRIM/RBCC family.
messages: Interacts with IFNAR1; this interaction prevents association of IFNAR1 with TYK2.

89673:CPSF4
gene id: 89673:CPSF4
uniprot id: A0A6J2N4L6
uniprot id: A0A6J2N4M7
uniprot id: A0A6J2N978
uniprot id: A0A7E6DBC9
uniprot id: A0A7E6DCF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

89673:LOC114500308
gene id: 89673:LOC114500308
uniprot id: A0A6J2M3G2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HPS5
gene id: 89673:HPS5
uniprot id: A0A6J2LSY7
uniprot id: A0A7E6E0I9
uniprot id: A0A7E6E123
uniprot id: A0A7E6E1S0
uniprot id: A0A7E6E1S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

89673:IFRD2
gene id: 89673:IFRD2
uniprot id: A0A6J2M6N5
names: Similarity
messages: Belongs to the IFRD family.

89673:ZDHHC17
gene id: 89673:ZDHHC17
uniprot id: A0A6J2N4P2
uniprot id: A0A7E6D5N8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:HPX
gene id: 89673:HPX
uniprot id: A0A6J2M0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemopexin family.
messages: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
messages: Secreted

89673:BHMT2
gene id: 89673:BHMT2
uniprot id: A0A6J2MQY3
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

89673:PLPPR5
gene id: 89673:PLPPR5
uniprot id: A0A7E6CVS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

89673:TMEM45B
gene id: 89673:TMEM45B
uniprot id: A0A6J2MWW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

89673:KCNK1
gene id: 89673:KCNK1
uniprot id: A0A6J2N5M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

89673:SLC15A4
gene id: 89673:SLC15A4
uniprot id: A0A6J2L1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

89673:ATP1B4
gene id: 89673:ATP1B4
uniprot id: A0A6J2MHU0
uniprot id: A0A6J2MMA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

89673:RIF1
gene id: 89673:RIF1
uniprot id: A0A6J2L9W7
uniprot id: A0A6J2LAG3
uniprot id: A0A7E6DJZ4
uniprot id: A0A7E6DJZ8
uniprot id: A0A7E6DK87
uniprot id: A0A7E6DK93
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

89673:PDCD10
gene id: 89673:PDCD10
uniprot id: A0A6J2L2F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

89673:ZNF446
gene id: 89673:ZNF446
uniprot id: A0A6J2N8K8
uniprot id: A0A7E6CQR5
uniprot id: A0A7E6CR78
uniprot id: A0A7E6CTF8
names: Subcellular Location Annotation
messages: Nucleus

89673:CDH15
gene id: 89673:CDH15
uniprot id: A0A6J2KSR4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:DUSP9
gene id: 89673:DUSP9
uniprot id: A0A6J2ML11
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

89673:RPL29
gene id: 89673:RPL29
uniprot id: A0A6J2M4N0
uniprot id: A0A7E6E575
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

89673:LOC114499111
gene id: 89673:LOC114499111
uniprot id: A0A7E6E1G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ADPRM
gene id: 89673:ADPRM
uniprot id: A0A7E6EC07
names: Similarity
names: Subunit
messages: Belongs to the ADPRibase-Mn family.
messages: Monomer.

89673:LOC114512404
gene id: 89673:LOC114512404
uniprot id: A0A6J2NAE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CAPN11
gene id: 89673:CAPN11
uniprot id: A0A6J2LKU8
names: Similarity
messages: Belongs to the peptidase C2 family.

89673:LOC114490362
gene id: 89673:LOC114490362
uniprot id: A0A7E6E874
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114499049
gene id: 89673:LOC114499049
uniprot id: A0A6J2LUV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:AKAP9
gene id: 89673:AKAP9
uniprot id: A0A6J2MLC9
uniprot id: A0A7E6CHS2
uniprot id: A0A7E6CHS8
uniprot id: A0A7E6CHV3
uniprot id: A0A7E6CHV8
uniprot id: A0A7E6CI14
uniprot id: A0A7E6CI22
uniprot id: A0A7E6CI63
uniprot id: A0A7E6CI69
uniprot id: A0A7E6CJT8
uniprot id: A0A7E6CJU3
names: Subcellular Location Annotation
messages: centrosome

89673:USP20
gene id: 89673:USP20
uniprot id: A0A6J2MYH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: centrosome
messages: perinuclear region

89673:ERBB4
gene id: 89673:ERBB4
uniprot id: A0A6J2LDT9
uniprot id: A0A7E6DI92
uniprot id: A0A7E6DIB7
uniprot id: A0A7E6DIG8
uniprot id: A0A7E6DIH1
uniprot id: A0A7E6DIL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

89673:B4GALNT4
gene id: 89673:B4GALNT4
uniprot id: A0A6J2LT36
uniprot id: A0A7E6E3F1
uniprot id: A0A7E6E456
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

89673:LOC114506601
gene id: 89673:LOC114506601
uniprot id: A0A7E6CGM0
names: Similarity
messages: Belongs to the peptidase M20A family.

89673:GRIA3
gene id: 89673:GRIA3
uniprot id: A0A6J2MGY9
uniprot id: A0A6J2MK81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

89673:CHD4
gene id: 89673:CHD4
uniprot id: A0A6J2N4K8
uniprot id: A0A6J2N6I6
uniprot id: A0A6J2NB54
uniprot id: A0A6J2NBU9
uniprot id: A0A7E6D1Q4
uniprot id: A0A7E6D1Q8
uniprot id: A0A7E6D1S0
uniprot id: A0A7E6D1S8
uniprot id: A0A7E6D1U8
uniprot id: A0A7E6D2K9
uniprot id: A0A7E6D2L4
uniprot id: A0A7E6D4G4
uniprot id: A0A7E6D4G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

89673:LOC114489171
gene id: 89673:LOC114489171
uniprot id: A0A6J2KUT0
uniprot id: A0A7E6CWG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GLMP family.
messages: Interacts (via lumenal domain) with lysosomal protein MFSD1; the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stability and lysosomal localization of MFSD1.
messages: Lysosome membrane
messages: Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.

89673:LOC114496610
gene id: 89673:LOC114496610
uniprot id: A0A6J2LQA4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

89673:CCNE1
gene id: 89673:CCNE1
uniprot id: A0A6J2KWT2
uniprot id: A0A7E6CQT1
names: Similarity
messages: Belongs to the cyclin family. Cyclin E subfamily.

89673:ZDHHC19
gene id: 89673:ZDHHC19
uniprot id: A0A6J2NEC7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:LOC114499100
gene id: 89673:LOC114499100
uniprot id: A0A6J2LYF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DAPK3
gene id: 89673:DAPK3
uniprot id: A0A6J2M919
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:OCEL1
gene id: 89673:OCEL1
uniprot id: A0A6J2ME36
uniprot id: A0A7E6EBF5
uniprot id: A0A7E6EBU9
names: Similarity
messages: Belongs to the ELL/occludin family.

89673:OPRK1
gene id: 89673:OPRK1
uniprot id: A0A6J2M8X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with SLC9A3R1. Interacts with GABARAPL1.
messages: Membrane

89673:TEF
gene id: 89673:TEF
uniprot id: A0A6J2N6G5
uniprot id: A0A6J2N862
uniprot id: A0A6J2N8I9
uniprot id: A0A6J2ND26
uniprot id: A0A6J2NDR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

89673:LOC114503833
gene id: 89673:LOC114503833
uniprot id: A0A6J2MGS3
uniprot id: A0A7E6EGC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.
messages: Secreted

89673:POLR3A
gene id: 89673:POLR3A
uniprot id: A0A6J2LRY3
uniprot id: A0A7E6DUI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

89673:SCAI
gene id: 89673:SCAI
uniprot id: A0A6J2LZF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAI family.
messages: Cytoplasm
messages: Interacts with DIAPH1. Forms a nuclear ternary complex with MRTFA and SRF.
messages: Nucleus
messages: Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity.

89673:HSDL2
gene id: 89673:HSDL2
uniprot id: A0A6J2MLJ8
names: Subcellular Location Annotation
messages: Peroxisome

89673:LOC114491127
gene id: 89673:LOC114491127
uniprot id: A0A7E6D2P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

89673:LOC114492128
gene id: 89673:LOC114492128
uniprot id: A0A6J2L5G1
names: Similarity
messages: Belongs to the serpin family.

89673:SF1
gene id: 89673:SF1
uniprot id: A0A6J2LW63
uniprot id: A0A6J2LW68
uniprot id: A0A6J2LXB1
uniprot id: A0A6J2LY96
uniprot id: A0A6J2M180
uniprot id: A0A6J2M187
uniprot id: A0A6J2M1P9
uniprot id: A0A6J2M1Q5
uniprot id: A0A7E6E214
uniprot id: A0A7E6E3G5
uniprot id: A0A7E6E3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

89673:MRPL11
gene id: 89673:MRPL11
uniprot id: A0A6J2M1L3
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

89673:HINT1
gene id: 89673:HINT1
uniprot id: A0A6J2MVR5
names: Similarity
messages: Belongs to the HINT family.

89673:LOC114492481
gene id: 89673:LOC114492481
uniprot id: A0A6J2L6S8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41 and VPS72/YL1. The NuA4 complex interacts with MYC and the adenovirus E1A protein. MORF4L1 may also participate in the formation of NuA4 related complexes which lack the KAT5/TIP60 catalytic subunit, but which include the SWI/SNF related protein SRCAP. Component of the MSIN3A histone deacetylase complex, which includes SIN3A, HDAC2, ARID4B, MORF4L1, RBBP4/RbAp48, and RBBP7/RbAp46. Interacts with MRFAP1 and RB1. May also interact with one or more as yet undefined members of the TLE (transducin-like enhancer of split) family of transcriptional repressors.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also a component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
messages: Nucleus

89673:AOC1
gene id: 89673:AOC1
uniprot id: A0A7E6CJ76
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

89673:UBA6
gene id: 89673:UBA6
uniprot id: A0A6J2L295
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

89673:ATL3
gene id: 89673:ATL3
uniprot id: A0A6J2LVY4
uniprot id: A0A6J2LWW8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

89673:DDO
gene id: 89673:DDO
uniprot id: A0A6J2LJ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

89673:MCU
gene id: 89673:MCU
uniprot id: A0A6J2LJY0
uniprot id: A0A6J2LPB0
uniprot id: A0A7E6DU68
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

89673:KIF1A
gene id: 89673:KIF1A
uniprot id: A0A7E6DHQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

89673:DENND11
gene id: 89673:DENND11
uniprot id: A0A6J2MP19
names: Similarity
messages: Belongs to the DENND11 family.

89673:LOC114508560
gene id: 89673:LOC114508560
uniprot id: A0A7E6CJY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

89673:TASOR2
gene id: 89673:TASOR2
uniprot id: A0A6J2L3F6
uniprot id: A0A7E6DNW0
uniprot id: A0A7E6DNW6
uniprot id: A0A7E6DPE9
uniprot id: A0A7E6DPH0
uniprot id: A0A7E6DPI0
names: Similarity
messages: Belongs to the TASOR family.

89673:DTX4
gene id: 89673:DTX4
uniprot id: A0A6J2M583
uniprot id: A0A7E6E2X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

89673:HNMT
gene id: 89673:HNMT
uniprot id: A0A6J2LDX7
uniprot id: A0A7E6DKM0
names: Function
names: Subunit
messages: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
messages: Monomer.

89673:THY1
gene id: 89673:THY1
uniprot id: A0A6J2M190
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
messages: Membrane

89673:FZD9
gene id: 89673:FZD9
uniprot id: A0A6J2N5W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

89673:CXCL10
gene id: 89673:CXCL10
uniprot id: A0A7E6DGR7
uniprot id: A0A7E6DGW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

89673:ACAD9
gene id: 89673:ACAD9
uniprot id: A0A6J2L4X4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

89673:E2F2
gene id: 89673:E2F2
uniprot id: A0A6J2LMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

89673:BEST3
gene id: 89673:BEST3
uniprot id: A0A7E6D6C4
uniprot id: A0A7E6D8I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:CDCA5
gene id: 89673:CDCA5
uniprot id: A0A6J2LYL3
uniprot id: A0A6J2M217
uniprot id: A0A7E6E3I6
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

89673:TTC39B
gene id: 89673:TTC39B
uniprot id: A0A6J2M392
uniprot id: A0A6J2M5I3
names: Similarity
messages: Belongs to the TTC39 family.

89673:NFIC
gene id: 89673:NFIC
uniprot id: A0A6J2M4S6
uniprot id: A0A6J2M6G7
uniprot id: A0A6J2M6W5
uniprot id: A0A6J2M9U5
uniprot id: A0A6J2MAE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

89673:LPIN2
gene id: 89673:LPIN2
uniprot id: A0A7E6CDY6
names: Similarity
messages: Belongs to the lipin family.

89673:MME
gene id: 89673:MME
uniprot id: A0A6J2L422
uniprot id: A0A7E6D2L7
names: Cofactor
messages: Binds 1 zinc ion per subunit.

89673:LOC118500744
gene id: 89673:LOC118500744
uniprot id: A0A7E6DTH5
uniprot id: A0A7E6DU55
uniprot id: A0A7E6DUK5
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC114488347
gene id: 89673:LOC114488347
uniprot id: A0A7E6CQ09
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:LOC114506837
gene id: 89673:LOC114506837
uniprot id: A0A7E6CGY6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

89673:TFCP2
gene id: 89673:TFCP2
uniprot id: A0A6J2N8W9
uniprot id: A0A7E6D7B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

89673:BAK1
gene id: 89673:BAK1
uniprot id: A0A6J2LE17
names: Similarity
messages: Belongs to the Bcl-2 family.

89673:TPPP3
gene id: 89673:TPPP3
uniprot id: A0A6J2KQJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPPP family.
messages: cytoskeleton

89673:F5
gene id: 89673:F5
uniprot id: A0A7E6CXQ9
uniprot id: A0A7E6CY84
names: Similarity
messages: Belongs to the multicopper oxidase family.

89673:IRF8
gene id: 89673:IRF8
uniprot id: A0A6J2KTI2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:SYNE2
gene id: 89673:SYNE2
uniprot id: A0A7E6CIJ1
uniprot id: A0A7E6CIJ6
uniprot id: A0A7E6CIK0
uniprot id: A0A7E6CIK1
uniprot id: A0A7E6CIU0
uniprot id: A0A7E6CIU7
uniprot id: A0A7E6CIV7
uniprot id: A0A7E6CIV9
uniprot id: A0A7E6CIW7
uniprot id: A0A7E6CKR9
uniprot id: A0A7E6CKT0
names: Similarity
messages: Belongs to the nesprin family.

89673:RANGRF
gene id: 89673:RANGRF
uniprot id: A0A6J2NEU1
uniprot id: A0A6J2NJM3
uniprot id: A0A7E6EC39
names: Similarity
messages: Belongs to the MOG1 family.

89673:DIABLO
gene id: 89673:DIABLO
uniprot id: A0A6J2N264
names: Subcellular Location Annotation
messages: Mitochondrion

89673:NXF3
gene id: 89673:NXF3
uniprot id: A0A6J2MKL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm

89673:RRP15
gene id: 89673:RRP15
uniprot id: A0A6J2NB56
names: Similarity
messages: Belongs to the RRP15 family.

89673:FAM118B
gene id: 89673:FAM118B
uniprot id: A0A6J2N3Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM118 family.
messages: Cajal body
messages: May play a role in Cajal bodies formation.

89673:LOC114503922
gene id: 89673:LOC114503922
uniprot id: A0A6J2MH15
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114489110
gene id: 89673:LOC114489110
uniprot id: A0A6J2KXY5
names: Similarity
messages: Belongs to the LCE family.

89673:LOC114499467
gene id: 89673:LOC114499467
uniprot id: A0A6J2LWT1
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

89673:CLGN
gene id: 89673:CLGN
uniprot id: A0A6J2MCD9
names: Similarity
messages: Belongs to the calreticulin family.

89673:LOC114506046
gene id: 89673:LOC114506046
uniprot id: A0A6J2MJ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystatin family.
messages: Secreted

89673:ANP32E
gene id: 89673:ANP32E
uniprot id: A0A6J2KTS8
uniprot id: A0A6J2KVZ6
uniprot id: A0A7E6CWB9
uniprot id: A0A7E6CWP3
names: Similarity
messages: Belongs to the ANP32 family.

89673:LOC114491014
gene id: 89673:LOC114491014
uniprot id: A0A6J2L439
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NUSAP1
gene id: 89673:NUSAP1
uniprot id: A0A6J2L4X0
uniprot id: A0A7E6E958
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

89673:PRPF3
gene id: 89673:PRPF3
uniprot id: A0A6J2KYJ3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

89673:LOC114511475
gene id: 89673:LOC114511475
uniprot id: A0A7E6CP68
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:NAGA
gene id: 89673:NAGA
uniprot id: A0A7E6DBE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

89673:SLC44A2
gene id: 89673:SLC44A2
uniprot id: A0A6J2M6K6
uniprot id: A0A6J2M713
uniprot id: A0A6J2M9Y5
uniprot id: A0A6J2MAI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

89673:IL4I1
gene id: 89673:IL4I1
uniprot id: A0A6J2N5N5
uniprot id: A0A7E6CNL1
uniprot id: A0A7E6CNM8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flavin monoamine oxidase family.
messages: Mitochondrion outer membrane
messages: Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.

89673:DUSP5
gene id: 89673:DUSP5
uniprot id: A0A6J2LQK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

89673:DZIP1
gene id: 89673:DZIP1
uniprot id: A0A6J2MWQ1
uniprot id: A0A7E6CJM6
uniprot id: A0A7E6CLQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: centriole
messages: cilium basal body

89673:ZMPSTE24
gene id: 89673:ZMPSTE24
uniprot id: A0A6J2LQP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

89673:LOC114502151
gene id: 89673:LOC114502151
uniprot id: A0A6J2M5P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:TUBGCP4
gene id: 89673:TUBGCP4
uniprot id: A0A6J2L7A6
uniprot id: A0A6J2LB00
uniprot id: A0A7E6E9T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

89673:UNC13B
gene id: 89673:UNC13B
uniprot id: A0A6J2N2E5
uniprot id: A0A6J2N8Q4
uniprot id: A0A6J2N9H3
uniprot id: A0A7E6DFG1
uniprot id: A0A7E6DFG5
uniprot id: A0A7E6DFG8
uniprot id: A0A7E6DFH1
uniprot id: A0A7E6DFH3
uniprot id: A0A7E6DFH6
uniprot id: A0A7E6DFI0
uniprot id: A0A7E6DFI6
uniprot id: A0A7E6DFJ2
uniprot id: A0A7E6DFJ9
uniprot id: A0A7E6DFK7
uniprot id: A0A7E6DFL2
uniprot id: A0A7E6DFL4
uniprot id: A0A7E6DFL9
uniprot id: A0A7E6DFM7
names: Subcellular Location Annotation
messages: Cytoplasm

89673:EXTL2
gene id: 89673:EXTL2
uniprot id: A0A7E6CX37
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:MED12L
gene id: 89673:MED12L
uniprot id: A0A7E6D682
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

89673:KIF26A
gene id: 89673:KIF26A
uniprot id: A0A7E6CTM8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:NADK2
gene id: 89673:NADK2
uniprot id: A0A6J2LX94
uniprot id: A0A6J2LXA8
uniprot id: A0A7E6DA63
uniprot id: A0A7E6DAW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

89673:LOC114513011
gene id: 89673:LOC114513011
uniprot id: A0A6J2N7P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RFNG
gene id: 89673:RFNG
uniprot id: A0A6J2MAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:ADAMTS18
gene id: 89673:ADAMTS18
uniprot id: A0A6J2KQT2
uniprot id: A0A7E6CMM0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:LOC114511442
gene id: 89673:LOC114511442
uniprot id: A0A7E6DGG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ALG12
gene id: 89673:ALG12
uniprot id: A0A6J2NEN1
uniprot id: A0A7E6D8R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114507482
gene id: 89673:LOC114507482
uniprot id: A0A6J2MSX2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:CENPA
gene id: 89673:CENPA
uniprot id: A0A7E6DX67
names: Similarity
messages: Belongs to the histone H3 family.

89673:PPME1
gene id: 89673:PPME1
uniprot id: A0A6J2LX77
uniprot id: A0A6J2M0M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

89673:LOC114509465
gene id: 89673:LOC114509465
uniprot id: A0A6J2N064
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

89673:SDR42E1
gene id: 89673:SDR42E1
uniprot id: A0A6J2KU45
names: Similarity
messages: Belongs to the 3-beta-HSD family.

89673:HEBP1
gene id: 89673:HEBP1
uniprot id: A0A6J2N771
names: Similarity
messages: Belongs to the HEBP family.

89673:IPO13
gene id: 89673:IPO13
uniprot id: A0A6J2LHJ2
uniprot id: A0A7E6DSA1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

89673:ZNF24
gene id: 89673:ZNF24
uniprot id: A0A6J2MMK0
names: Subcellular Location Annotation
messages: Nucleus

89673:NAGLU
gene id: 89673:NAGLU
uniprot id: A0A6J2MAF5
names: Subcellular Location Annotation
messages: Lysosome

89673:CMTM4
gene id: 89673:CMTM4
uniprot id: A0A6J2KQW2
uniprot id: A0A7E6CNX1
names: Subcellular Location Annotation
messages: Membrane

89673:EPC2
gene id: 89673:EPC2
uniprot id: A0A6J2L938
uniprot id: A0A6J2L9K3
uniprot id: A0A7E6DJZ9
uniprot id: A0A7E6DK99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

89673:PUSL1
gene id: 89673:PUSL1
uniprot id: A0A7E6DPF4
uniprot id: A0A7E6DQH2
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

89673:PFN1
gene id: 89673:PFN1
uniprot id: A0A6J2NE01
names: Similarity
messages: Belongs to the profilin family.

89673:LOC114499595
gene id: 89673:LOC114499595
uniprot id: A0A6J2LWJ1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:DEFB127
gene id: 89673:DEFB127
uniprot id: A0A6J2MJ63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

89673:TDRD5
gene id: 89673:TDRD5
uniprot id: A0A7E6CXP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDRD5 family.
messages: Cytoplasm
messages: Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly.

89673:MOCS1
gene id: 89673:MOCS1
uniprot id: A0A6J2LDW5
uniprot id: A0A6J2LHQ1
names: Similarity
messages: In the C-terminal section; belongs to the MoaC family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.

89673:SLC7A9
gene id: 89673:SLC7A9
uniprot id: A0A6J2N2F6
names: Subcellular Location Annotation
messages: Membrane

89673:DGKH
gene id: 89673:DGKH
uniprot id: A0A6J2MSG8
uniprot id: A0A6J2MX03
uniprot id: A0A7E6CJZ1
uniprot id: A0A7E6CJZ8
uniprot id: A0A7E6CM08
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

89673:RBM48
gene id: 89673:RBM48
uniprot id: A0A6J2MP28
names: Similarity
messages: Belongs to the RBM48 family.

89673:RFX1
gene id: 89673:RFX1
uniprot id: A0A6J2MAP1
uniprot id: A0A7E6E9E9
uniprot id: A0A7E6EA88
uniprot id: A0A7E6EB31
uniprot id: A0A7E6EBG4
names: Subcellular Location Annotation
messages: Nucleus

89673:MBOAT1
gene id: 89673:MBOAT1
uniprot id: A0A6J2LUU6
names: Subcellular Location Annotation
messages: Membrane

89673:PRDM2
gene id: 89673:PRDM2
uniprot id: A0A7E6DPW4
uniprot id: A0A7E6DPX8
uniprot id: A0A7E6DQJ7
uniprot id: A0A7E6DQL3
uniprot id: A0A7E6DQL8
names: Subcellular Location Annotation
messages: Nucleus

89673:CLDN15
gene id: 89673:CLDN15
uniprot id: A0A6J2MHP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:ITPR2
gene id: 89673:ITPR2
uniprot id: A0A6J2N897
uniprot id: A0A7E6D769
uniprot id: A0A7E6D7X3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

89673:ACTRT2
gene id: 89673:ACTRT2
uniprot id: A0A6J2LJN2
names: Similarity
messages: Belongs to the actin family.

89673:TMC3
gene id: 89673:TMC3
uniprot id: A0A7E6CTQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

89673:PGS1
gene id: 89673:PGS1
uniprot id: A0A6J2M9B9
uniprot id: A0A7E6EFC5
uniprot id: A0A7E6EFN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

89673:ONECUT3
gene id: 89673:ONECUT3
uniprot id: A0A6J2MEU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

89673:MZT2B
gene id: 89673:MZT2B
uniprot id: A0A6J2MWW6
uniprot id: A0A6J2MYI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOZART2 family.
messages: centrosome
messages: spindle

89673:RBP5
gene id: 89673:RBP5
uniprot id: A0A6J2N9L7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

89673:RSL24D1
gene id: 89673:RSL24D1
uniprot id: A0A6J2L715
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

89673:ARSA
gene id: 89673:ARSA
uniprot id: A0A6J2NDU4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

89673:MRPL58
gene id: 89673:MRPL58
uniprot id: A0A6J2MEN7
uniprot id: A0A7E6EG41
names: Subcellular Location Annotation
messages: Mitochondrion

89673:LOC114491701
gene id: 89673:LOC114491701
uniprot id: A0A6J2L2Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFamide neuropeptide family.
messages: Secreted

89673:LOC114510654
gene id: 89673:LOC114510654
uniprot id: A0A6J2N448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:STAT3
gene id: 89673:STAT3
uniprot id: A0A6J2M6W9
uniprot id: A0A6J2M890
uniprot id: A0A6J2MBK4
uniprot id: A0A6J2MC73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

89673:ORMDL2
gene id: 89673:ORMDL2
uniprot id: A0A6J2N875
uniprot id: A0A6J2N9X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

89673:ATP5PD
gene id: 89673:ATP5PD
uniprot id: A0A6J2M9K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

89673:LOC114510372
gene id: 89673:LOC114510372
uniprot id: A0A6J2N497
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114505527
gene id: 89673:LOC114505527
uniprot id: A0A7E6D1K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus

89673:SLITRK1
gene id: 89673:SLITRK1
uniprot id: A0A6J2MSD1
names: Similarity
messages: Belongs to the SLITRK family.

89673:ADAM29
gene id: 89673:ADAM29
uniprot id: A0A6J2MG37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SPA17
gene id: 89673:SPA17
uniprot id: A0A6J2MVY5
uniprot id: A0A7E6CWG2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.

89673:CXCL8
gene id: 89673:CXCL8
uniprot id: A0A6J2LCW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Chemotactic factor that mediates inflammatory response by attracting neutrophils, basophils, and T-cells to clear pathogens and protect the host from infection. Also plays an important role in neutrophil activation. Released in response to an inflammatory stimulus, exerts its effect by binding to the G-protein-coupled receptors CXCR1 and CXCR2, primarily found in neutrophils, monocytes and endothelial cells. G-protein heterotrimer (alpha, beta, gamma subunits) constitutively binds to CXCR1/CXCR2 receptor and activation by IL8 leads to beta and gamma subunits release from Galpha (GNAI2 in neutrophils) and activation of several downstream signaling pathways including PI3K and MAPK pathways.
messages: Homodimer.
messages: Secreted

89673:LOC114510118
gene id: 89673:LOC114510118
uniprot id: A0A6J2N317
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:AMN
gene id: 89673:AMN
uniprot id: A0A6J2L324
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:HTRA3
gene id: 89673:HTRA3
uniprot id: A0A6J2KW37
names: Similarity
messages: Belongs to the peptidase S1C family.

89673:NPNT
gene id: 89673:NPNT
uniprot id: A0A6J2L8N3
uniprot id: A0A6J2L9X3
uniprot id: A0A6J2LDV8
uniprot id: A0A7E6DRK9
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:NDUFA12
gene id: 89673:NDUFA12
uniprot id: A0A6J2NEX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:MED17
gene id: 89673:MED17
uniprot id: A0A6J2LXJ8
uniprot id: A0A7E6E0B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

89673:LOC114488221
gene id: 89673:LOC114488221
uniprot id: A0A6J2KWQ5
uniprot id: A0A7E6CME4
uniprot id: A0A7E6CPQ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:STOML2
gene id: 89673:STOML2
uniprot id: A0A6J2MNP7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

89673:PSMA5
gene id: 89673:PSMA5
uniprot id: A0A6J2L032
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

89673:DCTPP1
gene id: 89673:DCTPP1
uniprot id: A0A6J2LWK0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homotetramer.
messages: Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
messages: cytosol

89673:ORMDL3
gene id: 89673:ORMDL3
uniprot id: A0A6J2MCB1
uniprot id: A0A7E6EH07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Interacts with SPTLC1.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.

89673:GINS4
gene id: 89673:GINS4
uniprot id: A0A6J2MSK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

89673:LOC114514888
gene id: 89673:LOC114514888
uniprot id: A0A7E6E6I4
uniprot id: A0A7E6E804
uniprot id: A0A7E6E8A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

89673:LOC114513473
gene id: 89673:LOC114513473
uniprot id: A0A6J2N7S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114500643
gene id: 89673:LOC114500643
uniprot id: A0A6J2M550
uniprot id: A0A7E6E0R6
names: Similarity
messages: Belongs to the nucleobindin family.

89673:LOC114489250
gene id: 89673:LOC114489250
uniprot id: A0A6J2KUK5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:SPOCK2
gene id: 89673:SPOCK2
uniprot id: A0A6J2LN44
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:NKIRAS1
gene id: 89673:NKIRAS1
uniprot id: A0A7E6E8Y3
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

89673:AGAP1
gene id: 89673:AGAP1
uniprot id: A0A6J2LFB9
uniprot id: A0A6J2LIU0
uniprot id: A0A7E6DHL2
uniprot id: A0A7E6DHM0
uniprot id: A0A7E6DHQ9
uniprot id: A0A7E6DHT1
uniprot id: A0A7E6DHV0
uniprot id: A0A7E6DHV5
uniprot id: A0A7E6DHX5
uniprot id: A0A7E6DHY1
names: Similarity
messages: Belongs to the centaurin gamma-like family.

89673:ALAD
gene id: 89673:ALAD
uniprot id: A0A6J2MQK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer; active form. Homohexamer; low activity form.

89673:PKIB
gene id: 89673:PKIB
uniprot id: A0A7E6DMZ9
uniprot id: A0A7E6DN22
uniprot id: A0A7E6DNY3
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

89673:RPL28
gene id: 89673:RPL28
uniprot id: A0A6J2N5A4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

89673:PTPRB
gene id: 89673:PTPRB
uniprot id: A0A6J2NCH4
uniprot id: A0A7E6D5N1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

89673:ADAMTS19
gene id: 89673:ADAMTS19
uniprot id: A0A6J2MY96
uniprot id: A0A7E6CUU5
uniprot id: A0A7E6CVL2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:TAF12
gene id: 89673:TAF12
uniprot id: A0A6J2LN05
uniprot id: A0A6J2LTE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

89673:TLE3
gene id: 89673:TLE3
uniprot id: A0A6J2L0P8
uniprot id: A0A6J2L0P9
uniprot id: A0A6J2L343
uniprot id: A0A6J2L348
uniprot id: A0A6J2L517
uniprot id: A0A6J2L6D3
uniprot id: A0A6J2L6D8
uniprot id: A0A7E6DZQ0
uniprot id: A0A7E6DZQ6
uniprot id: A0A7E6E087
uniprot id: A0A7E6E0H6
uniprot id: A0A7E6E0K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

89673:LOC114514844
gene id: 89673:LOC114514844
uniprot id: A0A6J2NIA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:CRYGC
gene id: 89673:CRYGC
uniprot id: A0A6J2LK82
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

89673:NFASC
gene id: 89673:NFASC
uniprot id: A0A6J2N2S0
uniprot id: A0A6J2N2S5
uniprot id: A0A6J2N4H1
uniprot id: A0A6J2N948
uniprot id: A0A6J2N9Y8
uniprot id: A0A7E6CWJ7
uniprot id: A0A7E6CWP8
uniprot id: A0A7E6CX32
uniprot id: A0A7E6CXE5
uniprot id: A0A7E6CZ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

89673:ZSCAN16
gene id: 89673:ZSCAN16
uniprot id: A0A6J2KZ08
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114490732
gene id: 89673:LOC114490732
uniprot id: A0A6J2KYT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:GRB2
gene id: 89673:GRB2
uniprot id: A0A6J2MFB6
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

89673:CCDC126
gene id: 89673:CCDC126
uniprot id: A0A7E6CHU6
names: Subcellular Location Annotation
messages: Secreted

89673:RPS28
gene id: 89673:RPS28
uniprot id: A0A6J2M984
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS28 family.
messages: Component of the 40S small ribosomal subunit.

89673:TMCC1
gene id: 89673:TMCC1
uniprot id: A0A6J2M0T1
uniprot id: A0A6J2M252
uniprot id: A0A6J2M2W8
uniprot id: A0A6J2M2X5
uniprot id: A0A6J2M5R9
uniprot id: A0A6J2M5S4
uniprot id: A0A6J2M6C2
names: Similarity
messages: Belongs to the TEX28 family.

89673:ACTR6
gene id: 89673:ACTR6
uniprot id: A0A6J2N9L2
uniprot id: A0A7E6D811
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.

89673:SRP72
gene id: 89673:SRP72
uniprot id: A0A6J2L434
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

89673:RPL23
gene id: 89673:RPL23
uniprot id: A0A6J2MBL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

89673:ZIM2
gene id: 89673:ZIM2
uniprot id: A0A7E6CRD3
names: Subcellular Location Annotation
messages: Nucleus

89673:IL25
gene id: 89673:IL25
uniprot id: A0A6J2L3P1
names: Similarity
messages: Belongs to the IL-17 family.

89673:CD247
gene id: 89673:CD247
uniprot id: A0A7E6CWD8
uniprot id: A0A7E6CWP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

89673:LOC114511428
gene id: 89673:LOC114511428
uniprot id: A0A7E6CTJ0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

89673:EN1
gene id: 89673:EN1
uniprot id: A0A6J2NA15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

89673:BBS4
gene id: 89673:BBS4
uniprot id: A0A6J2L8F1
uniprot id: A0A7E6DY38
uniprot id: A0A7E6DY48
uniprot id: A0A7E6DY52
uniprot id: A0A7E6DZ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

89673:SWI5
gene id: 89673:SWI5
uniprot id: A0A7E6DGJ9
names: Function
names: Similarity
messages: Belongs to the SWI5/SAE3 family.
messages: Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.

89673:DNAJC27
gene id: 89673:DNAJC27
uniprot id: A0A6J2M2P1
names: Function
names: Subunit
messages: GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
messages: Interacts directly with MAPK1 (wild-type and kinase-deficient forms). Interacts directly (in GTP-bound form) with MAP2K1 (wild-type and kinase-deficient forms).

89673:LOC114504152
gene id: 89673:LOC114504152
uniprot id: A0A6J2MI33
names: Similarity
messages: Belongs to the peptidase S14 family.

89673:LOC114492667
gene id: 89673:LOC114492667
uniprot id: A0A6J2LA43
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

89673:PNOC
gene id: 89673:PNOC
uniprot id: A0A6J2ME69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

89673:IL24
gene id: 89673:IL24
uniprot id: A0A7E6CVU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Secreted

89673:WSCD2
gene id: 89673:WSCD2
uniprot id: A0A6J2N1L5
names: Similarity
messages: Belongs to the WSCD family.

89673:SLC1A2
gene id: 89673:SLC1A2
uniprot id: A0A6J2LZV5
uniprot id: A0A6J2M0E1
uniprot id: A0A7E6E0U4
uniprot id: A0A7E6E195
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

89673:FGD2
gene id: 89673:FGD2
uniprot id: A0A6J2LD36
uniprot id: A0A7E6DLR9
names: Subcellular Location Annotation
messages: cytoskeleton

89673:LOC114491797
gene id: 89673:LOC114491797
uniprot id: A0A6J2L362
uniprot id: A0A6J2L8C3
uniprot id: A0A7E6CMK1
uniprot id: A0A7E6CML0
uniprot id: A0A7E6CML8
uniprot id: A0A7E6CPZ6
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Belongs to the acylphosphatase family.

89673:ME2
gene id: 89673:ME2
uniprot id: A0A6J2MPJ3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

89673:FYTTD1
gene id: 89673:FYTTD1
uniprot id: A0A6J2L231
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UIF family.
messages: Nucleus speckle

89673:ADAMTS2
gene id: 89673:ADAMTS2
uniprot id: A0A6J2NEW3
uniprot id: A0A7E6ECJ6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:DOK2
gene id: 89673:DOK2
uniprot id: A0A6J2M9W1
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

89673:SPATA6L
gene id: 89673:SPATA6L
uniprot id: A0A6J2MQQ5
uniprot id: A0A7E6DEV4
uniprot id: A0A7E6DF00
names: Similarity
messages: Belongs to the SPATA6 family.

89673:ZFYVE27
gene id: 89673:ZFYVE27
uniprot id: A0A6J2LLQ5
uniprot id: A0A6J2LN21
uniprot id: A0A6J2LS43
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: growth cone membrane

89673:PLB1
gene id: 89673:PLB1
uniprot id: A0A7E6E478
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the 'GDSL' lipolytic enzyme family. Phospholipase B1 subfamily.
messages: Cell membrane
messages: Membrane

89673:SEMA5A
gene id: 89673:SEMA5A
uniprot id: A0A6J2LV22
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ZIC3
gene id: 89673:ZIC3
uniprot id: A0A6J2MHI6
uniprot id: A0A6J2MLW8
uniprot id: A0A7E6CZL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

89673:ACSL6
gene id: 89673:ACSL6
uniprot id: A0A6J2MV38
uniprot id: A0A6J2MWT4
uniprot id: A0A6J2N1B9
uniprot id: A0A6J2N202
uniprot id: A0A7E6CWX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion outer membrane

89673:USH2A
gene id: 89673:USH2A
uniprot id: A0A6J2N5J9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CCN4
gene id: 89673:CCN4
uniprot id: A0A7E6E8C1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:GPBP1L1
gene id: 89673:GPBP1L1
uniprot id: A0A6J2LQK4
uniprot id: A0A7E6DRT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

89673:STRIP1
gene id: 89673:STRIP1
uniprot id: A0A6J2KU37
names: Similarity
messages: Belongs to the STRIP family.

89673:RHBDF1
gene id: 89673:RHBDF1
uniprot id: A0A6J2LYA6
uniprot id: A0A7E6DCG8
uniprot id: A0A7E6DCN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

89673:LOC114499060
gene id: 89673:LOC114499060
uniprot id: A0A6J2LSU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PTH1R
gene id: 89673:PTH1R
uniprot id: A0A6J2M345
uniprot id: A0A7E6E5R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

89673:RNASE12
gene id: 89673:RNASE12
uniprot id: A0A7E6E697
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

89673:DLGAP2
gene id: 89673:DLGAP2
uniprot id: A0A7E6CJA0
names: Similarity
messages: Belongs to the SAPAP family.

89673:HLX
gene id: 89673:HLX
uniprot id: A0A6J2NAR3
names: Subcellular Location Annotation
messages: Nucleus

89673:GJB6
gene id: 89673:GJB6
uniprot id: A0A6J2NBR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:LOC114508601
gene id: 89673:LOC114508601
uniprot id: A0A7E6CK07
names: Similarity
messages: Belongs to the HINT family.

89673:L3MBTL1
gene id: 89673:L3MBTL1
uniprot id: A0A6J2MKZ4
uniprot id: A0A7E6CFI3
uniprot id: A0A7E6CHP5
names: Subcellular Location Annotation
messages: Nucleus

89673:FAM193B
gene id: 89673:FAM193B
uniprot id: A0A6J2MWM6
uniprot id: A0A7E6CTR0
uniprot id: A0A7E6CTS2
uniprot id: A0A7E6CTT2
uniprot id: A0A7E6CU91
uniprot id: A0A7E6CU95
uniprot id: A0A7E6CUH6
uniprot id: A0A7E6CWK5
names: Similarity
messages: Belongs to the FAM193 family.

89673:KCNC4
gene id: 89673:KCNC4
uniprot id: A0A6J2KWJ1
uniprot id: A0A6J2KY96
uniprot id: A0A7E6CXJ7
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114503409
gene id: 89673:LOC114503409
uniprot id: A0A6J2MF54
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

89673:CMPK1
gene id: 89673:CMPK1
uniprot id: A0A6J2LKJ3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

89673:LOC114508876
gene id: 89673:LOC114508876
uniprot id: A0A7E6CKE1
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

89673:ZP1
gene id: 89673:ZP1
uniprot id: A0A6J2LU57
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

89673:BUD23
gene id: 89673:BUD23
uniprot id: A0A6J2N085
uniprot id: A0A7E6DDH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

89673:LTV1
gene id: 89673:LTV1
uniprot id: A0A6J2LGV9
names: Similarity
messages: Belongs to the LTV1 family.

89673:CFAP53
gene id: 89673:CFAP53
uniprot id: A0A6J2MLI1
names: Similarity
messages: Belongs to the CFAP53 family.

89673:IFI30
gene id: 89673:IFI30
uniprot id: A0A6J2MAN4
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

89673:FOXE1
gene id: 89673:FOXE1
uniprot id: A0A7E6DFU7
names: Subcellular Location Annotation
messages: Nucleus

89673:TBX21
gene id: 89673:TBX21
uniprot id: A0A6J2M8Q5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:LOC114494366
gene id: 89673:LOC114494366
uniprot id: A0A7E6DJV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

89673:LOC114492772
gene id: 89673:LOC114492772
uniprot id: A0A6J2L5W7
uniprot id: A0A7E6DXB7
uniprot id: A0A7E6DXV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Interacts with FDX1/adrenodoxin.
messages: Mitochondrion inner membrane

89673:PPM1F
gene id: 89673:PPM1F
uniprot id: A0A6J2MY86
names: Similarity
messages: Belongs to the PP2C family.

89673:TRIM36
gene id: 89673:TRIM36
uniprot id: A0A6J2MSX1
uniprot id: A0A6J2MXT6
uniprot id: A0A7E6DB75
uniprot id: A0A7E6DCA1
uniprot id: A0A7E6DDE6
names: Subcellular Location Annotation
messages: cytoskeleton

89673:LOC114498904
gene id: 89673:LOC114498904
uniprot id: A0A6J2LTR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CCL5
gene id: 89673:CCL5
uniprot id: A0A6J2MES6
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

89673:LOC114502107
gene id: 89673:LOC114502107
uniprot id: A0A7E6E7H0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

89673:STAT5B
gene id: 89673:STAT5B
uniprot id: A0A6J2M803
uniprot id: A0A6J2M9I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

89673:ADAM30
gene id: 89673:ADAM30
uniprot id: A0A6J2KWA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RWDD3
gene id: 89673:RWDD3
uniprot id: A0A6J2KX38
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:LIX1L
gene id: 89673:LIX1L
uniprot id: A0A6J2KVD1
names: Similarity
messages: Belongs to the LIX1 family.

89673:SUV39H1
gene id: 89673:SUV39H1
uniprot id: A0A6J2MGG1
uniprot id: A0A6J2MGS1
uniprot id: A0A6J2MK09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

89673:RFC1
gene id: 89673:RFC1
uniprot id: A0A6J2L776
uniprot id: A0A7E6D8X3
uniprot id: A0A7E6D8Z8
uniprot id: A0A7E6D9T2
uniprot id: A0A7E6DBV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

89673:ATP9B
gene id: 89673:ATP9B
uniprot id: A0A6J2MMD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

89673:DNAJC18
gene id: 89673:DNAJC18
uniprot id: A0A6J2N1J2
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114510258
gene id: 89673:LOC114510258
uniprot id: A0A7E6CRA4
names: Subcellular Location Annotation
messages: Nucleus

89673:VCAN
gene id: 89673:VCAN
uniprot id: A0A6J2N282
uniprot id: A0A7E6DAM5
uniprot id: A0A7E6DD92
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:SLC15A2
gene id: 89673:SLC15A2
uniprot id: A0A6J2KYA7
uniprot id: A0A7E6D4B8
uniprot id: A0A7E6D6Y6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

89673:HNF4G
gene id: 89673:HNF4G
uniprot id: A0A6J2M5B1
uniprot id: A0A7E6E6K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

89673:NKX6-2
gene id: 89673:NKX6-2
uniprot id: A0A6J2LVF3
names: Subcellular Location Annotation
messages: Nucleus

89673:BSG
gene id: 89673:BSG
uniprot id: A0A6J2M8Z2
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Lateral cell membrane

89673:LOC114500789
gene id: 89673:LOC114500789
uniprot id: A0A7E6E391
uniprot id: A0A7E6E3G3
names: Subcellular Location Annotation
messages: Nucleus

89673:RPL14
gene id: 89673:RPL14
uniprot id: A0A6J2M596
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

89673:GRM2
gene id: 89673:GRM2
uniprot id: A0A6J2M592
uniprot id: A0A7E6E542
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

89673:PCSK2
gene id: 89673:PCSK2
uniprot id: A0A6J2MRN9
names: Similarity
messages: Belongs to the peptidase S8 family.

89673:NKX3-2
gene id: 89673:NKX3-2
uniprot id: A0A6J2LBH3
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114501436
gene id: 89673:LOC114501436
uniprot id: A0A6J2M2I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

89673:SHQ1
gene id: 89673:SHQ1
uniprot id: A0A6J2M6H5
names: Similarity
messages: Belongs to the SHQ1 family.

89673:SELENBP1
gene id: 89673:SELENBP1
uniprot id: A0A6J2KWG5
uniprot id: A0A7E6CVX0
uniprot id: A0A7E6CW82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Interacts with USP33.
messages: Membrane
messages: Nucleus
messages: cytosol

89673:MYO15B
gene id: 89673:MYO15B
uniprot id: A0A7E6CD88
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:ASB8
gene id: 89673:ASB8
uniprot id: A0A6J2N4X9
names: Function
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

89673:PLXNC1
gene id: 89673:PLXNC1
uniprot id: A0A6J2ND52
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:HSP90AB1
gene id: 89673:HSP90AB1
uniprot id: A0A6J2LCT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

89673:UBE2S
gene id: 89673:UBE2S
uniprot id: A0A6J2N5P8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:LOC114490203
gene id: 89673:LOC114490203
uniprot id: A0A6J2L2S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CCR9
gene id: 89673:CCR9
uniprot id: A0A6J2M571
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:ADCK5
gene id: 89673:ADCK5
uniprot id: A0A6J2NHG0
uniprot id: A0A7E6E8V9
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

89673:LOC114503098
gene id: 89673:LOC114503098
uniprot id: A0A6J2MD97
uniprot id: A0A7E6E9B1
uniprot id: A0A7E6EA44
uniprot id: A0A7E6EBC0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC24A3
gene id: 89673:SLC24A3
uniprot id: A0A6J2MP11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

89673:TACR2
gene id: 89673:TACR2
uniprot id: A0A6J2LUC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:GALNT1
gene id: 89673:GALNT1
uniprot id: A0A6J2MKU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:TGFBI
gene id: 89673:TGFBI
uniprot id: A0A6J2MWH0
names: Subcellular Location Annotation
messages: extracellular matrix

89673:SLC16A2
gene id: 89673:SLC16A2
uniprot id: A0A6J2MFF9
uniprot id: A0A6J2MIS3
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114488691
gene id: 89673:LOC114488691
uniprot id: A0A6J2KW20
uniprot id: A0A7E6CQ02
names: Similarity
messages: Belongs to the CEMIP family.

89673:CMTM8
gene id: 89673:CMTM8
uniprot id: A0A6J2M285
names: Subcellular Location Annotation
messages: Membrane

89673:ZSCAN25
gene id: 89673:ZSCAN25
uniprot id: A0A6J2L9S0
uniprot id: A0A7E6D8Z7
uniprot id: A0A7E6D9V8
names: Subcellular Location Annotation
messages: Nucleus

89673:PNN
gene id: 89673:PNN
uniprot id: A0A6J2L338
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

89673:PI4K2B
gene id: 89673:PI4K2B
uniprot id: A0A7E6D7W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

89673:CNRIP1
gene id: 89673:CNRIP1
uniprot id: A0A6J2M1F5
uniprot id: A0A7E6DYY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

89673:PALM3
gene id: 89673:PALM3
uniprot id: A0A7E6E9D7
uniprot id: A0A7E6EA65
uniprot id: A0A7E6EAF3
uniprot id: A0A7E6EB16
names: Similarity
messages: Belongs to the paralemmin family.

89673:STN1
gene id: 89673:STN1
uniprot id: A0A6J2LPH8
uniprot id: A0A7E6DV93
uniprot id: A0A7E6DVE0
uniprot id: A0A7E6DVV1
uniprot id: A0A7E6DVV4
uniprot id: A0A7E6DW77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the STN1 family.
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

89673:CD244
gene id: 89673:CD244
uniprot id: A0A6J2L0K7
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114500016
gene id: 89673:LOC114500016
uniprot id: A0A6J2LXD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

89673:CAMK1
gene id: 89673:CAMK1
uniprot id: A0A6J2M6Q8
uniprot id: A0A7E6E579
uniprot id: A0A7E6E6R5
uniprot id: A0A7E6E6W2
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:FGGY
gene id: 89673:FGGY
uniprot id: A0A6J2LQP2
uniprot id: A0A7E6DSD5
uniprot id: A0A7E6DSE3
uniprot id: A0A7E6DSW7
uniprot id: A0A7E6DSX0
uniprot id: A0A7E6DT19
uniprot id: A0A7E6DTE9
uniprot id: A0A7E6DTF5
names: Similarity
messages: Belongs to the FGGY kinase family.

89673:PDE4D
gene id: 89673:PDE4D
uniprot id: A0A6J2LXW4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:GPN1
gene id: 89673:GPN1
uniprot id: A0A6J2LWF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

89673:SRRT
gene id: 89673:SRRT
uniprot id: A0A7E6DBB9
names: Similarity
messages: Belongs to the ARS2 family.

89673:LOC114497610
gene id: 89673:LOC114497610
uniprot id: A0A7E6DQ11
uniprot id: A0A7E6DQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

89673:TNFRSF8
gene id: 89673:TNFRSF8
uniprot id: A0A7E6DPT7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114502513
gene id: 89673:LOC114502513
uniprot id: A0A7E6EFW9
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS28 family.
messages: Component of the 40S small ribosomal subunit.

89673:ALOX5
gene id: 89673:ALOX5
uniprot id: A0A6J2LI97
uniprot id: A0A6J2LM01
uniprot id: A0A7E6DTN5
uniprot id: A0A7E6DUB2
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114503096
gene id: 89673:LOC114503096
uniprot id: A0A6J2M8I5
uniprot id: A0A6J2MAK7
uniprot id: A0A6J2MD91
uniprot id: A0A6J2MDV2
uniprot id: A0A7E6EDU9
uniprot id: A0A7E6EE02
uniprot id: A0A7E6EF15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

89673:LOC114494156
gene id: 89673:LOC114494156
uniprot id: A0A7E6DNR4
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

89673:ARTN
gene id: 89673:ARTN
uniprot id: A0A6J2LV97
uniprot id: A0A7E6DRJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

89673:NOL10
gene id: 89673:NOL10
uniprot id: A0A6J2LZE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

89673:MED30
gene id: 89673:MED30
uniprot id: A0A6J2ND13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

89673:SNRPB
gene id: 89673:SNRPB
uniprot id: A0A6J2MLV9
uniprot id: A0A6J2MR89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

89673:HSPB6
gene id: 89673:HSPB6
uniprot id: A0A6J2N1D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Nucleus

89673:LOC114489380
gene id: 89673:LOC114489380
uniprot id: A0A6J2KUQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

89673:RPA1
gene id: 89673:RPA1
uniprot id: A0A6J2MCE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

89673:FERMT3
gene id: 89673:FERMT3
uniprot id: A0A6J2LVI6
names: Similarity
messages: Belongs to the kindlin family.

89673:TSPAN12
gene id: 89673:TSPAN12
uniprot id: A0A6J2MNL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:SRC
gene id: 89673:SRC
uniprot id: A0A6J2MIU2
uniprot id: A0A6J2MKZ7
uniprot id: A0A7E6CFE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:ARHGAP32
gene id: 89673:ARHGAP32
uniprot id: A0A6J2MT97
uniprot id: A0A6J2MZH5
uniprot id: A0A7E6CU18
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

89673:C6
gene id: 89673:C6
uniprot id: A0A6J2MIW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Component of the membrane attack complex (MAC). MAC assembly is initiated by proteolytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and 12-14 copies of the pore-forming subunit C9.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:RGN
gene id: 89673:RGN
uniprot id: A0A6J2MIL8
uniprot id: A0A6J2MM17
uniprot id: A0A7E6CYT9
uniprot id: A0A7E6D1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

89673:CERS5
gene id: 89673:CERS5
uniprot id: A0A6J2N7J5
uniprot id: A0A6J2ND12
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

89673:NME7
gene id: 89673:NME7
uniprot id: A0A6J2N431
uniprot id: A0A7E6CZ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: cilium axoneme

89673:MUTYH
gene id: 89673:MUTYH
uniprot id: A0A6J2LUP2
uniprot id: A0A6J2LUS8
uniprot id: A0A7E6DRP6
uniprot id: A0A7E6DRQ5
uniprot id: A0A7E6DSC3
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

89673:STAC
gene id: 89673:STAC
uniprot id: A0A6J2M8A9
names: Subcellular Location Annotation
messages: sarcolemma

89673:MAP1LC3C
gene id: 89673:MAP1LC3C
uniprot id: A0A6J2NAG6
uniprot id: A0A7E6CY47
names: Similarity
messages: Belongs to the ATG8 family.

89673:MASP2
gene id: 89673:MASP2
uniprot id: A0A6J2LN58
uniprot id: A0A7E6DQJ4
uniprot id: A0A7E6DQY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:PAX3
gene id: 89673:PAX3
uniprot id: A0A6J2LDN6
uniprot id: A0A7E6DIA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

89673:LIN28A
gene id: 89673:LIN28A
uniprot id: A0A6J2LPD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

89673:LOC114505198
gene id: 89673:LOC114505198
uniprot id: A0A6J2MLU0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:METTL3
gene id: 89673:METTL3
uniprot id: A0A6J2KXU2
uniprot id: A0A7E6E5B4
names: Similarity
messages: Belongs to the MT-A70-like family.

89673:KLHL36
gene id: 89673:KLHL36
uniprot id: A0A6J2NF63
names: Function
messages: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

89673:RRH
gene id: 89673:RRH
uniprot id: A0A6J2L7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

89673:MTURN
gene id: 89673:MTURN
uniprot id: A0A6J2MVS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

89673:SPRY2
gene id: 89673:SPRY2
uniprot id: A0A6J2MWR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: ruffle membrane

89673:SLC25A37
gene id: 89673:SLC25A37
uniprot id: A0A6J2MBF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:GNG3
gene id: 89673:GNG3
uniprot id: A0A6J2LX84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:EXOC3L2
gene id: 89673:EXOC3L2
uniprot id: A0A6J2N6H9
names: Similarity
messages: Belongs to the SEC6 family.

89673:LOC114509133
gene id: 89673:LOC114509133
uniprot id: A0A6J2MZ47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CCL1
gene id: 89673:CCL1
uniprot id: A0A6J2MD85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

89673:KPNA5
gene id: 89673:KPNA5
uniprot id: A0A6J2LBT7
uniprot id: A0A6J2LCZ3
uniprot id: A0A6J2LE28
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

89673:KHDC3L
gene id: 89673:KHDC3L
uniprot id: A0A7E6DM95
names: Similarity
messages: Belongs to the KHDC1 family.

89673:DMRTA2
gene id: 89673:DMRTA2
uniprot id: A0A6J2LQ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

89673:TUFM
gene id: 89673:TUFM
uniprot id: A0A6J2LPU8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

89673:LOC114500534
gene id: 89673:LOC114500534
uniprot id: A0A6J2M476
uniprot id: A0A7E6E242
names: Similarity
messages: Belongs to the peptidase A1 family.

89673:VAMP1
gene id: 89673:VAMP1
uniprot id: A0A6J2NE56
uniprot id: A0A7E6D204
uniprot id: A0A7E6D2P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

89673:LOC114505282
gene id: 89673:LOC114505282
uniprot id: A0A7E6CZ69
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

89673:TTN
gene id: 89673:TTN
uniprot id: A0A7E6DJ81
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

89673:LOC114495180
gene id: 89673:LOC114495180
uniprot id: A0A7E6DH86
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

89673:FGG
gene id: 89673:FGG
uniprot id: A0A6J2M8G0
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

89673:LOC114508150
gene id: 89673:LOC114508150
uniprot id: A0A7E6CJ17
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

89673:AGBL1
gene id: 89673:AGBL1
uniprot id: A0A7E6CTP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

89673:LOC114497384
gene id: 89673:LOC114497384
uniprot id: A0A6J2LM97
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:PLN
gene id: 89673:PLN
uniprot id: A0A7E6DNW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholamban family.
messages: Endoplasmic reticulum membrane
messages: Homopentamer.
messages: Membrane
messages: Mitochondrion membrane
messages: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
messages: Sarcoplasmic reticulum membrane

89673:TP63
gene id: 89673:TP63
uniprot id: A0A6J2KYQ4
uniprot id: A0A6J2KZB4
uniprot id: A0A6J2L101
uniprot id: A0A6J2L4F3
uniprot id: A0A7E6D3A3
uniprot id: A0A7E6D616
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Mitochondrion matrix
messages: Nucleus
messages: PML body
messages: centrosome

89673:LOC114500460
gene id: 89673:LOC114500460
uniprot id: A0A7E6E039
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114499086
gene id: 89673:LOC114499086
uniprot id: A0A7E6E1B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114511464
gene id: 89673:LOC114511464
uniprot id: A0A6J2N6V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IGFL family.
messages: Secreted

89673:LOC114504770
gene id: 89673:LOC114504770
uniprot id: A0A6J2MGG4
names: Similarity
messages: Belongs to the BEX family.

89673:FEZ1
gene id: 89673:FEZ1
uniprot id: A0A6J2MYZ0
names: Similarity
messages: Belongs to the zygin family.

89673:CFAP97
gene id: 89673:CFAP97
uniprot id: A0A6J2MRI4
names: Similarity
messages: Belongs to the CFAP97 family.

89673:PIF1
gene id: 89673:PIF1
uniprot id: A0A7E6CFT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

89673:EYA1
gene id: 89673:EYA1
uniprot id: A0A7E6E694
uniprot id: A0A7E6E6A3
uniprot id: A0A7E6E6A8
uniprot id: A0A7E6E6T0
uniprot id: A0A7E6E6U1
uniprot id: A0A7E6E6U4
uniprot id: A0A7E6E742
uniprot id: A0A7E6E745
uniprot id: A0A7E6E751
uniprot id: A0A7E6E760
uniprot id: A0A7E6E7R7
uniprot id: A0A7E6E7S5
uniprot id: A0A7E6E7T0
uniprot id: A0A7E6E7X3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

89673:HTRA4
gene id: 89673:HTRA4
uniprot id: A0A7E6CKQ7
names: Similarity
messages: Belongs to the peptidase S1C family.

89673:TMEM106C
gene id: 89673:TMEM106C
uniprot id: A0A6J2ND36
names: Similarity
messages: Belongs to the TMEM106 family.

89673:FAM161A
gene id: 89673:FAM161A
uniprot id: A0A6J2LXG5
uniprot id: A0A7E6DYV0
names: Similarity
messages: Belongs to the FAM161 family.

89673:TMEM200B
gene id: 89673:TMEM200B
uniprot id: A0A6J2LJ94
uniprot id: A0A7E6DRX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

89673:LOC114505594
gene id: 89673:LOC114505594
uniprot id: A0A7E6D0F6
names: Similarity
messages: Belongs to the SPT20 family.

89673:LOC114503122
gene id: 89673:LOC114503122
uniprot id: A0A6J2M8L2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TMEM255A
gene id: 89673:TMEM255A
uniprot id: A0A6J2MEQ8
uniprot id: A0A6J2MGH9
uniprot id: A0A6J2MKM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

89673:CNOT10
gene id: 89673:CNOT10
uniprot id: A0A6J2M293
uniprot id: A0A6J2M7X9
uniprot id: A0A7E6E4Z9
uniprot id: A0A7E6E545
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT10 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
messages: Cytoplasm
messages: Nucleus

89673:ALAS1
gene id: 89673:ALAS1
uniprot id: A0A6J2M7P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

89673:PHOSPHO2
gene id: 89673:PHOSPHO2
uniprot id: A0A6J2LHQ4
uniprot id: A0A7E6DJR5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

89673:NIPAL3
gene id: 89673:NIPAL3
uniprot id: A0A6J2LPW3
uniprot id: A0A7E6DRK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

89673:LIPG
gene id: 89673:LIPG
uniprot id: A0A6J2MJK3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:MSI2
gene id: 89673:MSI2
uniprot id: A0A6J2M888
uniprot id: A0A6J2MDK9
uniprot id: A0A7E6EDC1
uniprot id: A0A7E6EDX9
uniprot id: A0A7E6EE33
uniprot id: A0A7E6EEX1
uniprot id: A0A7E6EF44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

89673:LOC114499106
gene id: 89673:LOC114499106
uniprot id: A0A7E6E241
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HOXD13
gene id: 89673:HOXD13
uniprot id: A0A6J2LG64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

89673:CCDC153
gene id: 89673:CCDC153
uniprot id: A0A7E6E4A2
names: Similarity
messages: Belongs to the UPF0610 family.

89673:IL12A
gene id: 89673:IL12A
uniprot id: A0A6J2L018
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity. Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits. Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2. In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes. As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine. Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers. Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites.
messages: Secreted

89673:LOC114511466
gene id: 89673:LOC114511466
uniprot id: A0A7E6CP09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IGFL family.
messages: Secreted

89673:SGF29
gene id: 89673:SGF29
uniprot id: A0A6J2LLG6
names: Subcellular Location Annotation
messages: Nucleus

89673:ARRB1
gene id: 89673:ARRB1
uniprot id: A0A6J2LVB1
uniprot id: A0A6J2LXC5
uniprot id: A0A6J2M0A4
uniprot id: A0A7E6DZR9
uniprot id: A0A7E6DZS5
uniprot id: A0A7E6E0Y6
names: Similarity
messages: Belongs to the arrestin family.

89673:LOC114499695
gene id: 89673:LOC114499695
uniprot id: A0A6J2M0Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EIPR1 family.
messages: trans-Golgi network

89673:KRT222
gene id: 89673:KRT222
uniprot id: A0A6J2MBA1
uniprot id: A0A6J2MH85
names: Similarity
messages: Belongs to the intermediate filament family.

89673:KANSL2
gene id: 89673:KANSL2
uniprot id: A0A6J2NE14
uniprot id: A0A7E6D710
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

89673:SLC9A3
gene id: 89673:SLC9A3
uniprot id: A0A6J2ND48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

89673:LOC114514695
gene id: 89673:LOC114514695
uniprot id: A0A6J2NI13
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

89673:PLA2G2A
gene id: 89673:PLA2G2A
uniprot id: A0A6J2LUX7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

89673:LOC114509373
gene id: 89673:LOC114509373
uniprot id: A0A7E6DCA9
names: Subcellular Location Annotation
messages: Membrane

89673:FAXC
gene id: 89673:FAXC
uniprot id: A0A7E6DN82
names: Similarity
messages: Belongs to the FAX family.

89673:LOC114514587
gene id: 89673:LOC114514587
uniprot id: A0A6J2NAS8
uniprot id: A0A6J2NHM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:ISL1
gene id: 89673:ISL1
uniprot id: A0A6J2MJX0
names: Subcellular Location Annotation
messages: Nucleus

89673:RBP2
gene id: 89673:RBP2
uniprot id: A0A6J2M992
uniprot id: A0A7E6E4U3
uniprot id: A0A7E6E6E6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

89673:CEP170B
gene id: 89673:CEP170B
uniprot id: A0A6J2L4V5
names: Similarity
messages: Belongs to the CEP170 family.

89673:PTK2
gene id: 89673:PTK2
uniprot id: A0A6J2NH59
uniprot id: A0A7E6E6Y2
uniprot id: A0A7E6E6Y6
uniprot id: A0A7E6E7I1
uniprot id: A0A7E6E7U7
uniprot id: A0A7E6E8C9
uniprot id: A0A7E6E8D4
uniprot id: A0A7E6E8R2
uniprot id: A0A7E6E8R7
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

89673:MEIS2
gene id: 89673:MEIS2
uniprot id: A0A6J2L0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

89673:MED14
gene id: 89673:MED14
uniprot id: A0A6J2MJ09
uniprot id: A0A7E6CZ53
uniprot id: A0A7E6D007
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

89673:AP3S1
gene id: 89673:AP3S1
uniprot id: A0A6J2LR59
uniprot id: A0A6J2LV75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

89673:LOC118502201
gene id: 89673:LOC118502201
uniprot id: A0A7E6EDE7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

89673:ST6GAL1
gene id: 89673:ST6GAL1
uniprot id: A0A7E6D348
uniprot id: A0A7E6D353
uniprot id: A0A7E6D388
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:LOC118502347
gene id: 89673:LOC118502347
uniprot id: A0A7E6EG90
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:LOC114509646
gene id: 89673:LOC114509646
uniprot id: A0A7E6CX60
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

89673:HTT
gene id: 89673:HTT
uniprot id: A0A6J2L221
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the huntingtin family.
messages: Cytoplasm
messages: May play a role in microtubule-mediated transport or vesicle function.
messages: Nucleus

89673:TPMT
gene id: 89673:TPMT
uniprot id: A0A7E6DTV5
uniprot id: A0A7E6DUA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm
messages: Monomer.

89673:DNMT3A
gene id: 89673:DNMT3A
uniprot id: A0A7E6DWL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

89673:FABP3
gene id: 89673:FABP3
uniprot id: A0A6J2LKD1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

89673:LOC114511347
gene id: 89673:LOC114511347
uniprot id: A0A7E6CPT0
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

89673:SPO11
gene id: 89673:SPO11
uniprot id: A0A6J2MS58
names: Similarity
messages: Belongs to the TOP6A family.

89673:LOC114500752
gene id: 89673:LOC114500752
uniprot id: A0A7E6E216
uniprot id: A0A7E6E2W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MTR
gene id: 89673:MTR
uniprot id: A0A6J2N577
uniprot id: A0A6J2NAN8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
messages: Cytoplasm
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

89673:ERI1
gene id: 89673:ERI1
uniprot id: A0A6J2MS14
names: Subcellular Location Annotation
messages: Cytoplasm

89673:SLC66A2
gene id: 89673:SLC66A2
uniprot id: A0A6J2MIQ9
uniprot id: A0A6J2MKW5
uniprot id: A0A7E6CGN3
names: Subcellular Location Annotation
messages: Membrane

89673:PMVK
gene id: 89673:PMVK
uniprot id: A0A6J2KZ62
uniprot id: A0A7E6CXV7
names: Subcellular Location Annotation
messages: cytosol

89673:FBN2
gene id: 89673:FBN2
uniprot id: A0A6J2L3J9
uniprot id: A0A7E6DB67
uniprot id: A0A7E6DCE7
uniprot id: A0A7E6DDF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:LOC114505039
gene id: 89673:LOC114505039
uniprot id: A0A7E6D1I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

89673:ANAPC16
gene id: 89673:ANAPC16
uniprot id: A0A6J2LJT5
uniprot id: A0A6J2LN46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

89673:P3H3
gene id: 89673:P3H3
uniprot id: A0A6J2NFI1
names: Similarity
messages: Belongs to the leprecan family.

89673:KPNA2
gene id: 89673:KPNA2
uniprot id: A0A6J2MAG7
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

89673:AXIN1
gene id: 89673:AXIN1
uniprot id: A0A6J2LNQ9
uniprot id: A0A6J2LNR9
uniprot id: A0A7E6DCX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus

89673:CNKSR3
gene id: 89673:CNKSR3
uniprot id: A0A7E6DPS8
names: Similarity
messages: Belongs to the CNKSR family.

89673:OXCT1
gene id: 89673:OXCT1
uniprot id: A0A6J2M2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

89673:ADRB2
gene id: 89673:ADRB2
uniprot id: A0A6J2MWU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
messages: Cell membrane
messages: Early endosome
messages: Golgi apparatus
messages: Membrane

89673:EIF2S2
gene id: 89673:EIF2S2
uniprot id: A0A6J2MHD8
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

89673:CPEB2
gene id: 89673:CPEB2
uniprot id: A0A7E6D8Z4
names: Similarity
messages: Belongs to the RRM CPEB family.

89673:SH3RF3
gene id: 89673:SH3RF3
uniprot id: A0A6J2LKH2
uniprot id: A0A7E6DTP2
uniprot id: A0A7E6DUE0
names: Similarity
messages: Belongs to the SH3RF family.

89673:TAFA5
gene id: 89673:TAFA5
uniprot id: A0A7E6D8N2
uniprot id: A0A7E6DBK4
names: Similarity
messages: Belongs to the TAFA family.

89673:ATP1A1
gene id: 89673:ATP1A1
uniprot id: A0A6J2KUY7
uniprot id: A0A6J2KY86
uniprot id: A0A7E6CWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

89673:LOC114512111
gene id: 89673:LOC114512111
uniprot id: A0A7E6CXR2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SLC35A2
gene id: 89673:SLC35A2
uniprot id: A0A6J2MGD1
uniprot id: A0A6J2MGN0
uniprot id: A0A6J2MKF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

89673:AZGP1
gene id: 89673:AZGP1
uniprot id: A0A6J2LA22
uniprot id: A0A7E6D942
names: Similarity
messages: Belongs to the MHC class I family.

89673:LOC114498903
gene id: 89673:LOC114498903
uniprot id: A0A6J2LXK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HTRA1
gene id: 89673:HTRA1
uniprot id: A0A6J2LJW3
names: Similarity
messages: Belongs to the peptidase S1C family.

89673:TMEM94
gene id: 89673:TMEM94
uniprot id: A0A6J2M748
uniprot id: A0A6J2M915
uniprot id: A0A6J2MBT7
uniprot id: A0A7E6EEJ2
uniprot id: A0A7E6EG47
uniprot id: A0A7E6EGA8
names: Subcellular Location Annotation
messages: Membrane

89673:PARD3
gene id: 89673:PARD3
uniprot id: A0A6J2L4T4
uniprot id: A0A6J2L4T9
uniprot id: A0A6J2L4U4
uniprot id: A0A6J2L5H4
uniprot id: A0A6J2L734
uniprot id: A0A6J2L9I4
uniprot id: A0A6J2LAT5
uniprot id: A0A6J2LAT9
uniprot id: A0A7E6D1U0
uniprot id: A0A7E6D1U2
uniprot id: A0A7E6D1V8
uniprot id: A0A7E6D1Y7
uniprot id: A0A7E6D209
uniprot id: A0A7E6D2B4
uniprot id: A0A7E6D2I0
uniprot id: A0A7E6D2S6
uniprot id: A0A7E6D367
uniprot id: A0A7E6D373
uniprot id: A0A7E6D3L0
uniprot id: A0A7E6D3U6
uniprot id: A0A7E6D3Z4
uniprot id: A0A7E6D488
uniprot id: A0A7E6D5C7
uniprot id: A0A7E6D5J6
uniprot id: A0A7E6D5P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

89673:DBNL
gene id: 89673:DBNL
uniprot id: A0A6J2KXN6
uniprot id: A0A6J2L2X2
uniprot id: A0A7E6CHE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: Synapse
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: cytoskeleton
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

89673:LOC114513266
gene id: 89673:LOC114513266
uniprot id: A0A6J2NEC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TLR3
gene id: 89673:TLR3
uniprot id: A0A7E6CL36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

89673:LOC114498412
gene id: 89673:LOC114498412
uniprot id: A0A7E6E0E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

89673:ENTPD6
gene id: 89673:ENTPD6
uniprot id: A0A7E6CEB3
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

89673:LOC114509253
gene id: 89673:LOC114509253
uniprot id: A0A6J2MT69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

89673:MRPL46
gene id: 89673:MRPL46
uniprot id: A0A6J2KRY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

89673:FOXK2
gene id: 89673:FOXK2
uniprot id: A0A6J2MEK7
names: Subcellular Location Annotation
messages: Nucleus

89673:HSD17B2
gene id: 89673:HSD17B2
uniprot id: A0A6J2KQX8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:TNPO2
gene id: 89673:TNPO2
uniprot id: A0A6J2MFS8
names: Subcellular Location Annotation
messages: Cytoplasm

89673:RRP8
gene id: 89673:RRP8
uniprot id: A0A6J2M4B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Component of the eNoSC complex.
messages: Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase.
messages: nucleolus

89673:LOC114502437
gene id: 89673:LOC114502437
uniprot id: A0A6J2M554
names: Similarity
messages: Belongs to the intermediate filament family.

89673:STAC2
gene id: 89673:STAC2
uniprot id: A0A6J2MEF0
uniprot id: A0A7E6EEK6
names: Subcellular Location Annotation
messages: sarcolemma

89673:INPP4B
gene id: 89673:INPP4B
uniprot id: A0A6J2MA18
uniprot id: A0A6J2MC27
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

89673:DNAJC25
gene id: 89673:DNAJC25
uniprot id: A0A6J2N530
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAJC25 family.
messages: Membrane

89673:DDI1
gene id: 89673:DDI1
uniprot id: A0A6J2M1Q0
names: Similarity
messages: Belongs to the DDI1 family.

89673:SLC7A6OS
gene id: 89673:SLC7A6OS
uniprot id: A0A6J2KUM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

89673:DDB1
gene id: 89673:DDB1
uniprot id: A0A6J2M3D2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDB1 family.
messages: Component of complexes involved in DNA repair and protein ubiquitination. May play a role in the regulation of the circadian clock.
messages: Component of the UV-DDB complex.
messages: Nucleus
messages: The core of the protein consists of three WD40 beta-propeller domains.

89673:RAB3IL1
gene id: 89673:RAB3IL1
uniprot id: A0A6J2LVL2
uniprot id: A0A6J2LXN2
uniprot id: A0A7E6E1M9
uniprot id: A0A7E6E271
uniprot id: A0A7E6E2C1
uniprot id: A0A7E6E333
names: Similarity
messages: Belongs to the SEC2 family.

89673:LYPLA2
gene id: 89673:LYPLA2
uniprot id: A0A6J2LK10
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

89673:LOC114510783
gene id: 89673:LOC114510783
uniprot id: A0A7E6CRE5
names: Similarity
messages: Belongs to the MHC class I family.

89673:LOC114504778
gene id: 89673:LOC114504778
uniprot id: A0A6J2MKE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

89673:ADA
gene id: 89673:ADA
uniprot id: A0A7E6CFM5
uniprot id: A0A7E6CFR0
uniprot id: A0A7E6CHR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

89673:LOC114495389
gene id: 89673:LOC114495389
uniprot id: A0A6J2LGF3
uniprot id: A0A7E6DIW6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

89673:HSPG2
gene id: 89673:HSPG2
uniprot id: A0A7E6DQA1
uniprot id: A0A7E6DQA9
uniprot id: A0A7E6DQB6
uniprot id: A0A7E6DQC0
uniprot id: A0A7E6DQC5
uniprot id: A0A7E6DQZ4
uniprot id: A0A7E6DQZ9
uniprot id: A0A7E6DR06
uniprot id: A0A7E6DR26
uniprot id: A0A7E6DR31
uniprot id: A0A7E6DRG1
uniprot id: A0A7E6DRG8
uniprot id: A0A7E6DRH5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

89673:TINAG
gene id: 89673:TINAG
uniprot id: A0A6J2LH02
uniprot id: A0A7E6DMD2
names: Similarity
messages: Belongs to the peptidase C1 family.

89673:LOC114514660
gene id: 89673:LOC114514660
uniprot id: A0A6J2NHX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

89673:ZC3H12A
gene id: 89673:ZC3H12A
uniprot id: A0A6J2LQS0
names: Similarity
messages: Belongs to the ZC3H12 family.

89673:SH3BGRL2
gene id: 89673:SH3BGRL2
uniprot id: A0A6J2LAY8
uniprot id: A0A6J2LFQ3
uniprot id: A0A7E6DMB4
uniprot id: A0A7E6DMU9
names: Similarity
messages: Belongs to the SH3BGR family.

89673:ACYP2
gene id: 89673:ACYP2
uniprot id: A0A6J2M1M4
uniprot id: A0A7E6DX94
uniprot id: A0A7E6DXE5
uniprot id: A0A7E6DY86
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ARAP3
gene id: 89673:ARAP3
uniprot id: A0A6J2MZL3
uniprot id: A0A7E6CUX0
names: Subcellular Location Annotation
messages: Cytoplasm

89673:SH3GL1
gene id: 89673:SH3GL1
uniprot id: A0A6J2M9R4
uniprot id: A0A7E6E8Y2
uniprot id: A0A7E6E9Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Implicated in endocytosis. May recruit other proteins to membranes with high curvature.
messages: Membrane

89673:LOC118500483
gene id: 89673:LOC118500483
uniprot id: A0A7E6DP76
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

89673:LOC114500518
gene id: 89673:LOC114500518
uniprot id: A0A6J2LZ56
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ARRDC2
gene id: 89673:ARRDC2
uniprot id: A0A7E6E9X9
uniprot id: A0A7E6EBJ3
names: Similarity
messages: Belongs to the arrestin family.

89673:TMEM11
gene id: 89673:TMEM11
uniprot id: A0A6J2NJD2
uniprot id: A0A7E6EBJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in mitochondrial morphogenesis.

89673:MED29
gene id: 89673:MED29
uniprot id: A0A6J2N623
uniprot id: A0A7E6CLB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 29 family.
messages: Nucleus

89673:RHBDL2
gene id: 89673:RHBDL2
uniprot id: A0A6J2LPX8
uniprot id: A0A7E6DRW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Membrane

89673:CFTR
gene id: 89673:CFTR
uniprot id: A0A6J2MUI0
uniprot id: A0A7E6CIE4
uniprot id: A0A7E6CIG7
uniprot id: A0A7E6CIP7
uniprot id: A0A7E6CIQ2
uniprot id: A0A7E6CIS9
uniprot id: A0A7E6CKL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Monomer; does not require oligomerization for channel activity. May form oligomers in the membrane (By similarity). Interacts with SLC26A3, SLC26A6 and SLC9A3R1 (By similarity). Interacts with SHANK2 (By similarity). Interacts with MYO6 (By similarity). Interacts (via C-terminus) with GOPC (via PDZ domain); this promotes CFTR internalization and thereby decreases channel activity. Interacts with SLC4A7 through SLC9A3R1. Found in a complex with MYO5B and RAB11A. Interacts with ANO1. Interacts with SLC26A8 (By similarity). Interacts with AHCYL1; the interaction increases CFTR activity (By similarity). Interacts with CSE1L (By similarity). The core-glycosylated form interacts with GORASP2 (via PDZ GRASP-type 1 domain) in respone to ER stress (By similarity). Interacts with MARCHF2; the interaction leads to CFTR ubiqtuitination and degradation.
messages: Recycling endosome membrane

89673:HOMER3
gene id: 89673:HOMER3
uniprot id: A0A6J2M6F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

89673:GTF2H4
gene id: 89673:GTF2H4
uniprot id: A0A6J2LBP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

89673:TMPRSS2
gene id: 89673:TMPRSS2
uniprot id: A0A6J2KZ53
uniprot id: A0A7E6D500
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ZSCAN22
gene id: 89673:ZSCAN22
uniprot id: A0A6J2N7R8
names: Subcellular Location Annotation
messages: Nucleus

89673:SAXO2
gene id: 89673:SAXO2
uniprot id: A0A6J2KY66
names: Similarity
messages: Belongs to the FAM154 family.

89673:CRTC2
gene id: 89673:CRTC2
uniprot id: A0A6J2KUU2
uniprot id: A0A6J2KWI7
uniprot id: A0A7E6CY37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

89673:SARDH
gene id: 89673:SARDH
uniprot id: A0A6J2MBD4
names: Similarity
messages: Belongs to the GcvT family.

89673:KIF5B
gene id: 89673:KIF5B
uniprot id: A0A7E6DX15
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:ABRACL
gene id: 89673:ABRACL
uniprot id: A0A6J2LGT9
names: Similarity
messages: Belongs to the costars family.

89673:LOC114503639
gene id: 89673:LOC114503639
uniprot id: A0A7E6E963
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:POLL
gene id: 89673:POLL
uniprot id: A0A6J2LV59
uniprot id: A0A7E6DV24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

89673:ABHD3
gene id: 89673:ABHD3
uniprot id: A0A7E6CDS7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

89673:LOC114506111
gene id: 89673:LOC114506111
uniprot id: A0A6J2MNC4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:LOC114508389
gene id: 89673:LOC114508389
uniprot id: A0A7E6CJH3
names: Similarity
messages: Belongs to the HMGB family.

89673:CDH9
gene id: 89673:CDH9
uniprot id: A0A6J2M3A4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:MTMR11
gene id: 89673:MTMR11
uniprot id: A0A7E6CVJ8
uniprot id: A0A7E6CW01
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

89673:CHAF1A
gene id: 89673:CHAF1A
uniprot id: A0A6J2M9C3
uniprot id: A0A7E6E9R5
uniprot id: A0A7E6EAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHAF1A family.
messages: Nucleus

89673:GSTM3
gene id: 89673:GSTM3
uniprot id: A0A6J2KU53
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

89673:SLIT2
gene id: 89673:SLIT2
uniprot id: A0A6J2L6Z5
uniprot id: A0A6J2L8B3
uniprot id: A0A6J2LCA5
uniprot id: A0A7E6D755
uniprot id: A0A7E6D789
uniprot id: A0A7E6D7A8
uniprot id: A0A7E6D7D9
uniprot id: A0A7E6D7W2
uniprot id: A0A7E6D7W7
uniprot id: A0A7E6D7Y4
uniprot id: A0A7E6DA23
uniprot id: A0A7E6DA48
uniprot id: A0A7E6DA58
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:B3GAT3
gene id: 89673:B3GAT3
uniprot id: A0A6J2LVV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:SIX5
gene id: 89673:SIX5
uniprot id: A0A6J2N6D7
names: Subcellular Location Annotation
messages: Nucleus

89673:ADRA1B
gene id: 89673:ADRA1B
uniprot id: A0A6J2N0B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

89673:STK10
gene id: 89673:STK10
uniprot id: A0A6J2MXX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Cell membrane

89673:LOC114504144
gene id: 89673:LOC114504144
uniprot id: A0A6J2MI08
names: Similarity
messages: Belongs to the KRTAP type 3 family.

89673:TAZ
gene id: 89673:TAZ
uniprot id: A0A6J2MH36
uniprot id: A0A6J2MHG6
uniprot id: A0A6J2MLD6
uniprot id: A0A7E6D0L1
uniprot id: A0A7E6D1A1
uniprot id: A0A7E6D1A5
uniprot id: A0A7E6D368
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acyltransferase which is required to remodel newly synthesized phospholipid cardiolipin, a key component of the mitochondrial inner membrane. Required for the initiation of mitophagy. Required to ensure progression of spermatocytes through meiosis.
messages: Associates with multiple protein complexes.
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

89673:ZFHX4
gene id: 89673:ZFHX4
uniprot id: A0A6J2M7Z8
uniprot id: A0A7E6E798
names: Subcellular Location Annotation
messages: Nucleus

89673:SIAH1
gene id: 89673:SIAH1
uniprot id: A0A6J2KQ55
uniprot id: A0A6J2KSE4
uniprot id: A0A7E6CQX0
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

89673:BMP15
gene id: 89673:BMP15
uniprot id: A0A6J2MI45
names: Similarity
messages: Belongs to the TGF-beta family.

89673:TJP1
gene id: 89673:TJP1
uniprot id: A0A6J2KRI1
uniprot id: A0A6J2KS44
uniprot id: A0A7E6CPE3
uniprot id: A0A7E6CPF3
uniprot id: A0A7E6CPL5
uniprot id: A0A7E6CPL9
uniprot id: A0A7E6CPP8
uniprot id: A0A7E6CPQ3
uniprot id: A0A7E6CRW6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

89673:ZDHHC24
gene id: 89673:ZDHHC24
uniprot id: A0A6J2M018
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:VAT1L
gene id: 89673:VAT1L
uniprot id: A0A6J2KQU9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

89673:HSBP1L1
gene id: 89673:HSBP1L1
uniprot id: A0A6J2MQ41
names: Similarity
messages: Belongs to the HSBP1 family.

89673:PTDSS1
gene id: 89673:PTDSS1
uniprot id: A0A6J2NIB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:NUDT18
gene id: 89673:NUDT18
uniprot id: A0A6J2MD81
names: Similarity
messages: Belongs to the Nudix hydrolase family.

89673:CKAP2L
gene id: 89673:CKAP2L
uniprot id: A0A6J2LUK8
names: Similarity
messages: Belongs to the CKAP2 family.

89673:IL6ST
gene id: 89673:IL6ST
uniprot id: A0A7E6D9S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

89673:TUBB4B
gene id: 89673:TUBB4B
uniprot id: A0A6J2L588
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

89673:GUCA2A
gene id: 89673:GUCA2A
uniprot id: A0A6J2LLS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

89673:TFIP11
gene id: 89673:TFIP11
uniprot id: A0A6J2MZZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFP11/STIP family.
messages: Identified in the spliceosome C complex. Found in the Intron Large (IL) complex, a post-mRNA release spliceosomal complex containing the excised intron, U2, U5 and U6 snRNPs, and splicing factors. Interacts with TUFT1. Interacts with DHX15; indicative for a recruitment of DHX15 to the IL complex. Interacts with GCFC2.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
messages: Nucleus

89673:ROM1
gene id: 89673:ROM1
uniprot id: A0A6J2LYF7
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

89673:NCAPH2
gene id: 89673:NCAPH2
uniprot id: A0A6J2NA18
uniprot id: A0A7E6D8T4
uniprot id: A0A7E6D8W1
uniprot id: A0A7E6DBR3
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

89673:LOC114489254
gene id: 89673:LOC114489254
uniprot id: A0A6J2KV50
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:MTOR
gene id: 89673:MTOR
uniprot id: A0A6J2LJC4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

89673:NDUFA2
gene id: 89673:NDUFA2
uniprot id: A0A6J2MUI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:LOC114505641
gene id: 89673:LOC114505641
uniprot id: A0A7E6D3A6
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:MTF2
gene id: 89673:MTF2
uniprot id: A0A6J2LLN7
uniprot id: A0A7E6DT04
uniprot id: A0A7E6DTL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

89673:TPM4
gene id: 89673:TPM4
uniprot id: A0A6J2M5Z4
uniprot id: A0A6J2M7E8
uniprot id: A0A6J2MAQ4
uniprot id: A0A6J2MBA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

89673:FUCA1
gene id: 89673:FUCA1
uniprot id: A0A6J2LQW9
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

89673:RPL3L
gene id: 89673:RPL3L
uniprot id: A0A6J2MRS3
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

89673:BCAR1
gene id: 89673:BCAR1
uniprot id: A0A6J2KSD2
uniprot id: A0A6J2KW95
uniprot id: A0A7E6CMG1
uniprot id: A0A7E6CMJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

89673:SFMBT1
gene id: 89673:SFMBT1
uniprot id: A0A6J2M3P7
uniprot id: A0A7E6E5X9
uniprot id: A0A7E6E622
names: Subcellular Location Annotation
messages: Nucleus

89673:ELAC1
gene id: 89673:ELAC1
uniprot id: A0A6J2MMY5
uniprot id: A0A7E6CGL6
names: Subunit
messages: Homodimer.

89673:RCE1
gene id: 89673:RCE1
uniprot id: A0A6J2LX40
uniprot id: A0A6J2M017
uniprot id: A0A7E6E272
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:RPS13
gene id: 89673:RPS13
uniprot id: A0A6J2LWA6
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

89673:LOC114507012
gene id: 89673:LOC114507012
uniprot id: A0A7E6CGS4
names: Similarity
messages: Belongs to the TCTP family.

89673:KYAT3
gene id: 89673:KYAT3
uniprot id: A0A6J2LQA9
uniprot id: A0A7E6DTM3
names: Subunit
messages: Homodimer.

89673:INTS12
gene id: 89673:INTS12
uniprot id: A0A6J2L6N6
uniprot id: A0A7E6DRM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Integrator subunit 12 family.
messages: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, INTS11/CPSF3L and INTS12.
messages: Nucleus

89673:CHURC1
gene id: 89673:CHURC1
uniprot id: A0A6J2L311
names: Similarity
messages: Belongs to the Churchill family.

89673:CD79B
gene id: 89673:CD79B
uniprot id: A0A7E6ECU8
uniprot id: A0A7E6EDD4
uniprot id: A0A7E6EEK9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:LOC114508650
gene id: 89673:LOC114508650
uniprot id: A0A6J2MSF0
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

89673:RIOK2
gene id: 89673:RIOK2
uniprot id: A0A6J2MQ95
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

89673:ATP2A1
gene id: 89673:ATP2A1
uniprot id: A0A6J2L5Y4
uniprot id: A0A7E6DD08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

89673:LAMTOR2
gene id: 89673:LAMTOR2
uniprot id: A0A6J2KT04
uniprot id: A0A7E6CXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

89673:MYSM1
gene id: 89673:MYSM1
uniprot id: A0A6J2LS11
uniprot id: A0A7E6DS76
uniprot id: A0A7E6DSV9
uniprot id: A0A7E6DSW2
uniprot id: A0A7E6DT09
uniprot id: A0A7E6DTE0
names: Similarity
messages: Belongs to the peptidase M67A family. MYSM1 subfamily.

89673:LOC114511135
gene id: 89673:LOC114511135
uniprot id: A0A6J2N5X0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HGF
gene id: 89673:HGF
uniprot id: A0A6J2MMV3
uniprot id: A0A6J2MPS4
uniprot id: A0A7E6CI85
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

89673:SLC25A48
gene id: 89673:SLC25A48
uniprot id: A0A6J2N1T3
uniprot id: A0A7E6CR68
uniprot id: A0A7E6CR92
uniprot id: A0A7E6CRJ9
uniprot id: A0A7E6CRM6
uniprot id: A0A7E6CTV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:PPP3R1
gene id: 89673:PPP3R1
uniprot id: A0A6J2LRJ8
uniprot id: A0A6J2LX18
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

89673:ABCC2
gene id: 89673:ABCC2
uniprot id: A0A6J2LN29
uniprot id: A0A7E6DVV5
uniprot id: A0A7E6DWA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

89673:GNGT2
gene id: 89673:GNGT2
uniprot id: A0A6J2ME49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:RSAD1
gene id: 89673:RSAD1
uniprot id: A0A6J2M9A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Mitochondrion

89673:RPL13
gene id: 89673:RPL13
uniprot id: A0A6J2KQU8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

89673:DPF2
gene id: 89673:DPF2
uniprot id: A0A6J2LUE4
names: Similarity
messages: Belongs to the requiem/DPF family.

89673:LTBP4
gene id: 89673:LTBP4
uniprot id: A0A6J2MYI9
uniprot id: A0A6J2N088
uniprot id: A0A6J2N4V2
uniprot id: A0A7E6CLM8
uniprot id: A0A7E6CLN4
uniprot id: A0A7E6CLP4
uniprot id: A0A7E6CNU5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:TPRG1L
gene id: 89673:TPRG1L
uniprot id: A0A6J2LKP7
names: Similarity
messages: Belongs to the TPRG1 family.

89673:SLC51A
gene id: 89673:SLC51A
uniprot id: A0A6J2KWR2
uniprot id: A0A7E6D4G2
uniprot id: A0A7E6D554
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114490170
gene id: 89673:LOC114490170
uniprot id: A0A6J2L2P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114511140
gene id: 89673:LOC114511140
uniprot id: A0A6J2N6P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

89673:USP5
gene id: 89673:USP5
uniprot id: A0A6J2N4F3
uniprot id: A0A6J2NAY2
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

89673:BLOC1S6
gene id: 89673:BLOC1S6
uniprot id: A0A6J2L9Y3
uniprot id: A0A7E6EC15
uniprot id: A0A7E6EC30
uniprot id: A0A7E6ECX9
uniprot id: A0A7E6ED61
uniprot id: A0A7E6ED66
names: Function
names: Similarity
messages: Belongs to the BLOC1S6 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

89673:EPHA2
gene id: 89673:EPHA2
uniprot id: A0A6J2LLG1
uniprot id: A0A7E6DQ03
names: Subcellular Location Annotation
messages: Membrane

89673:BORCS7
gene id: 89673:BORCS7
uniprot id: A0A6J2LSR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS7 family.
messages: Membrane

89673:ATRNL1
gene id: 89673:ATRNL1
uniprot id: A0A6J2LQP6
uniprot id: A0A7E6DVJ7
uniprot id: A0A7E6DVR5
uniprot id: A0A7E6DWI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:APLP2
gene id: 89673:APLP2
uniprot id: A0A6J2MSM7
uniprot id: A0A6J2MYV5
uniprot id: A0A6J2MYW0
uniprot id: A0A6J2MZD0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:ADGRB1
gene id: 89673:ADGRB1
uniprot id: A0A7E6E700
names: Subcellular Location Annotation
messages: Membrane

89673:ITGAV
gene id: 89673:ITGAV
uniprot id: A0A6J2LC50
uniprot id: A0A6J2LFZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:NR2C2
gene id: 89673:NR2C2
uniprot id: A0A6J2M451
uniprot id: A0A6J2M4Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

89673:NAALAD2
gene id: 89673:NAALAD2
uniprot id: A0A6J2LVG6
uniprot id: A0A7E6E0N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

89673:CCND3
gene id: 89673:CCND3
uniprot id: A0A6J2LB95
uniprot id: A0A6J2LCE9
uniprot id: A0A7E6DP37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

89673:SMPD1
gene id: 89673:SMPD1
uniprot id: A0A6J2LYT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

89673:PCYOX1
gene id: 89673:PCYOX1
uniprot id: A0A6J2LTM0
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

89673:MAEL
gene id: 89673:MAEL
uniprot id: A0A7E6CY28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the maelstrom family.
messages: Nucleus
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.

89673:RGMA
gene id: 89673:RGMA
uniprot id: A0A6J2KRZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

89673:THADA
gene id: 89673:THADA
uniprot id: A0A6J2LT00
uniprot id: A0A7E6DXA0
uniprot id: A0A7E6DXN1
uniprot id: A0A7E6DY36
uniprot id: A0A7E6DYI5
names: Similarity
messages: Belongs to the THADA family.

89673:DPY19L1
gene id: 89673:DPY19L1
uniprot id: A0A6J2MUC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

89673:FAR2
gene id: 89673:FAR2
uniprot id: A0A6J2NGX9
uniprot id: A0A7E6DA17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

89673:FOLH1B
gene id: 89673:FOLH1B
uniprot id: A0A6J2M0A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

89673:SAR1B
gene id: 89673:SAR1B
uniprot id: A0A6J2MXM2
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

89673:LOC114503354
gene id: 89673:LOC114503354
uniprot id: A0A7E6D9E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:LOC114492577
gene id: 89673:LOC114492577
uniprot id: A0A6J2L4X8
uniprot id: A0A6J2L9N1
uniprot id: A0A7E6DFL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

89673:IGFBP5
gene id: 89673:IGFBP5
uniprot id: A0A6J2LBV6
uniprot id: A0A6J2LGV0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:UBE2D2
gene id: 89673:UBE2D2
uniprot id: A0A6J2MYF9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:HOMEZ
gene id: 89673:HOMEZ
uniprot id: A0A6J2L515
names: Subcellular Location Annotation
messages: Nucleus

89673:TCEA3
gene id: 89673:TCEA3
uniprot id: A0A7E6DQD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

89673:RFTN1
gene id: 89673:RFTN1
uniprot id: A0A6J2M3F7
uniprot id: A0A7E6E547
uniprot id: A0A7E6E633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

89673:PLG
gene id: 89673:PLG
uniprot id: A0A6J2KX86
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: Secreted

89673:MPDU1
gene id: 89673:MPDU1
uniprot id: A0A6J2NE74
uniprot id: A0A7E6EBH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane
messages: Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.

89673:USP15
gene id: 89673:USP15
uniprot id: A0A6J2NAT2
uniprot id: A0A6J2NFL3
uniprot id: A0A7E6D5S6
uniprot id: A0A7E6D5V4
uniprot id: A0A7E6D6G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

89673:FKTN
gene id: 89673:FKTN
uniprot id: A0A6J2MLP1
uniprot id: A0A6J2MNI3
uniprot id: A0A7E6DFS4
names: Similarity
messages: Belongs to the LicD transferase family.

89673:TBK1
gene id: 89673:TBK1
uniprot id: A0A6J2N6S5
names: Subcellular Location Annotation
messages: Cytoplasm

89673:GET4
gene id: 89673:GET4
uniprot id: A0A6J2MYP1
names: Similarity
messages: Belongs to the GET4 family.

89673:ERBIN
gene id: 89673:ERBIN
uniprot id: A0A6J2LE25
uniprot id: A0A6J2LE29
uniprot id: A0A7E6DA83
uniprot id: A0A7E6DAB8
uniprot id: A0A7E6DAK6
uniprot id: A0A7E6DD35
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

89673:LOC114512488
gene id: 89673:LOC114512488
uniprot id: A0A7E6CY42
names: Similarity
messages: Belongs to the cystatin family.

89673:CKAP2
gene id: 89673:CKAP2
uniprot id: A0A6J2MSW8
uniprot id: A0A6J2MXT2
uniprot id: A0A7E6CJL7
uniprot id: A0A7E6CJR6
uniprot id: A0A7E6CJS0
uniprot id: A0A7E6CLP2
names: Similarity
messages: Belongs to the CKAP2 family.

89673:SPTLC2
gene id: 89673:SPTLC2
uniprot id: A0A6J2L604
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

89673:LOC114504886
gene id: 89673:LOC114504886
uniprot id: A0A7E6D1M2
names: Subcellular Location Annotation
messages: Nucleus

89673:MBTPS2
gene id: 89673:MBTPS2
uniprot id: A0A6J2MJ55
names: Similarity
messages: Belongs to the peptidase M50A family.

89673:SERP1
gene id: 89673:SERP1
uniprot id: A0A6J2KZJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

89673:TMEM126A
gene id: 89673:TMEM126A
uniprot id: A0A6J2LUI4
names: Subcellular Location Annotation
messages: Membrane

89673:COQ10B
gene id: 89673:COQ10B
uniprot id: A0A6J2LHN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

89673:LSM5
gene id: 89673:LSM5
uniprot id: A0A6J2MQ49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

89673:GALNT6
gene id: 89673:GALNT6
uniprot id: A0A6J2NFE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:SLA
gene id: 89673:SLA
uniprot id: A0A6J2NIH5
uniprot id: A0A7E6E7G7
names: Subcellular Location Annotation
messages: Cytoplasm

89673:PTGFR
gene id: 89673:PTGFR
uniprot id: A0A6J2LP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:IDH3G
gene id: 89673:IDH3G
uniprot id: A0A6J2MHA4
uniprot id: A0A6J2MKJ8
uniprot id: A0A7E6D032
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

89673:TVP23A
gene id: 89673:TVP23A
uniprot id: A0A6J2M269
uniprot id: A0A7E6DBQ8
uniprot id: A0A7E6DBZ0
uniprot id: A0A7E6DCX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

89673:PRPF19
gene id: 89673:PRPF19
uniprot id: A0A6J2LZ82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

89673:MRPS9
gene id: 89673:MRPS9
uniprot id: A0A6J2LYA4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

89673:NKD1
gene id: 89673:NKD1
uniprot id: A0A7E6CQZ9
uniprot id: A0A7E6CRB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

89673:LOC114499169
gene id: 89673:LOC114499169
uniprot id: A0A7E6E493
names: Subcellular Location Annotation
messages: Nucleus

89673:GNG7
gene id: 89673:GNG7
uniprot id: A0A6J2MBK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:VWA1
gene id: 89673:VWA1
uniprot id: A0A6J2LN26
names: Subcellular Location Annotation
messages: Membrane
messages: basement membrane

89673:L3MBTL2
gene id: 89673:L3MBTL2
uniprot id: A0A6J2NFN9
uniprot id: A0A7E6D8E9
uniprot id: A0A7E6D8H7
uniprot id: A0A7E6D8K4
uniprot id: A0A7E6D996
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, BAT8 and YAF2.
messages: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.

89673:SCAMP4
gene id: 89673:SCAMP4
uniprot id: A0A6J2MC85
uniprot id: A0A7E6E8S6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114507398
gene id: 89673:LOC114507398
uniprot id: A0A6J2MND8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC2A13
gene id: 89673:SLC2A13
uniprot id: A0A6J2N9Q1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

89673:LOC114489685
gene id: 89673:LOC114489685
uniprot id: A0A6J2L188
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

89673:CTSF
gene id: 89673:CTSF
uniprot id: A0A6J2M1X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

89673:LOC114509916
gene id: 89673:LOC114509916
uniprot id: A0A6J2MXK0
uniprot id: A0A7E6CUL1
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

89673:MNAT1
gene id: 89673:MNAT1
uniprot id: A0A6J2L8K6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

89673:MAGI1
gene id: 89673:MAGI1
uniprot id: A0A6J2M5W7
uniprot id: A0A7E6E758
uniprot id: A0A7E6E763
uniprot id: A0A7E6E768
uniprot id: A0A7E6E773
uniprot id: A0A7E6E7Q3
uniprot id: A0A7E6E7Q7
uniprot id: A0A7E6E7R1
uniprot id: A0A7E6E816
uniprot id: A0A7E6E822
uniprot id: A0A7E6E827
uniprot id: A0A7E6E833
uniprot id: A0A7E6E8L8
uniprot id: A0A7E6E8M4
uniprot id: A0A7E6E8N0
uniprot id: A0A7E6E8N7
uniprot id: A0A7E6E8P2
uniprot id: A0A7E6E8Y7
uniprot id: A0A7E6E8Z1
uniprot id: A0A7E6E8Z7
names: Subcellular Location Annotation
messages: Membrane

89673:SPRN
gene id: 89673:SPRN
uniprot id: A0A7E6DVW2
names: Function
names: Similarity
messages: Belongs to the SPRN family.
messages: Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP.

89673:IPMK
gene id: 89673:IPMK
uniprot id: A0A6J2LLJ6
uniprot id: A0A6J2LQG5
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

89673:MTCP1
gene id: 89673:MTCP1
uniprot id: A0A6J2MK25
names: Similarity
messages: Belongs to the TCL1 family.

89673:LOC114507238
gene id: 89673:LOC114507238
uniprot id: A0A6J2MSJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114495208
gene id: 89673:LOC114495208
uniprot id: A0A7E6DIP1
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

89673:FOXD3
gene id: 89673:FOXD3
uniprot id: A0A6J2LRS5
names: Subcellular Location Annotation
messages: Nucleus

89673:AGO1
gene id: 89673:AGO1
uniprot id: A0A6J2LKY6
uniprot id: A0A6J2LP95
uniprot id: A0A7E6DRW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

89673:SUPT20H
gene id: 89673:SUPT20H
uniprot id: A0A7E6CJE8
uniprot id: A0A7E6CJF2
uniprot id: A0A7E6CJG5
uniprot id: A0A7E6CJH1
uniprot id: A0A7E6CJJ8
uniprot id: A0A7E6CJK2
uniprot id: A0A7E6CJM2
uniprot id: A0A7E6CJM5
uniprot id: A0A7E6CLJ4
names: Similarity
messages: Belongs to the SPT20 family.

89673:LOC114505243
gene id: 89673:LOC114505243
uniprot id: A0A7E6CZF7
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:PPARGC1B
gene id: 89673:PPARGC1B
uniprot id: A0A6J2N215
uniprot id: A0A7E6CU79
names: Subcellular Location Annotation
messages: Nucleus

89673:CALHM4
gene id: 89673:CALHM4
uniprot id: A0A6J2LH84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

89673:FUT10
gene id: 89673:FUT10
uniprot id: A0A6J2MS47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors.

89673:PLK2
gene id: 89673:PLK2
uniprot id: A0A6J2LNY6
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

89673:TSEN2
gene id: 89673:TSEN2
uniprot id: A0A7E6E5S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

89673:LOC114490986
gene id: 89673:LOC114490986
uniprot id: A0A6J2L0F5
uniprot id: A0A6J2L216
uniprot id: A0A6J2L409
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

89673:PHKG2
gene id: 89673:PHKG2
uniprot id: A0A6J2L9K4
uniprot id: A0A7E6DDW8
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

89673:RAD21
gene id: 89673:RAD21
uniprot id: A0A6J2NGV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

89673:IL36RN
gene id: 89673:IL36RN
uniprot id: A0A6J2M2H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

89673:LOC114489528
gene id: 89673:LOC114489528
uniprot id: A0A6J2KWT5
uniprot id: A0A6J2L138
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:APOA1
gene id: 89673:APOA1
uniprot id: A0A6J2LSA5
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

89673:NMI
gene id: 89673:NMI
uniprot id: A0A6J2LCP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NMI family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

89673:TSPAN17
gene id: 89673:TSPAN17
uniprot id: A0A6J2MZY7
uniprot id: A0A7E6CRW4
uniprot id: A0A7E6CUI5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114495176
gene id: 89673:LOC114495176
uniprot id: A0A6J2LJA2
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

89673:CDK10
gene id: 89673:CDK10
uniprot id: A0A6J2KXD4
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:PPDPFL
gene id: 89673:PPDPFL
uniprot id: A0A6J2M8Z3
names: Similarity
messages: Belongs to the PPDPF family.

89673:NRN1
gene id: 89673:NRN1
uniprot id: A0A6J2LS01
names: Similarity
messages: Belongs to the neuritin family.

89673:BAX
gene id: 89673:BAX
uniprot id: A0A6J2N579
uniprot id: A0A7E6CN89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

89673:CCL16
gene id: 89673:CCL16
uniprot id: A0A6J2MD82
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

89673:HOXA9
gene id: 89673:HOXA9
uniprot id: A0A6J2MMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

89673:LOC114503642
gene id: 89673:LOC114503642
uniprot id: A0A6J2MFN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114489378
gene id: 89673:LOC114489378
uniprot id: A0A6J2L0L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

89673:RIPOR1
gene id: 89673:RIPOR1
uniprot id: A0A7E6CLU6
uniprot id: A0A7E6CLV1
uniprot id: A0A7E6CLV9
uniprot id: A0A7E6CLX0
uniprot id: A0A7E6CM10
uniprot id: A0A7E6CP33
names: Similarity
messages: Belongs to the RIPOR family.

89673:KCNH6
gene id: 89673:KCNH6
uniprot id: A0A6J2MER7
uniprot id: A0A7E6ECW5
names: Subcellular Location Annotation
messages: Membrane

89673:ACVR1C
gene id: 89673:ACVR1C
uniprot id: A0A6J2LI61
uniprot id: A0A7E6DK31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

89673:CD2
gene id: 89673:CD2
uniprot id: A0A6J2KUR3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:GJB7
gene id: 89673:GJB7
uniprot id: A0A6J2LK36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:HTR7
gene id: 89673:HTR7
uniprot id: A0A6J2LQ51
uniprot id: A0A6J2LRC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:ACY1
gene id: 89673:ACY1
uniprot id: A0A6J2M8U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Cytoplasm

89673:TAC3
gene id: 89673:TAC3
uniprot id: A0A6J2N8M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

89673:EI24
gene id: 89673:EI24
uniprot id: A0A6J2MVL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EI24 family.
messages: Membrane

89673:HCFC2
gene id: 89673:HCFC2
uniprot id: A0A6J2N5K2
uniprot id: A0A7E6D8R3
names: Subcellular Location Annotation
messages: Nucleus

89673:PGC
gene id: 89673:PGC
uniprot id: A0A6J2LFA1
names: Function
names: Similarity
messages: Belongs to the peptidase A1 family.
messages: Hydrolyzes a variety of proteins.

89673:FOXB1
gene id: 89673:FOXB1
uniprot id: A0A6J2L867
names: Subcellular Location Annotation
messages: Nucleus

89673:MCOLN3
gene id: 89673:MCOLN3
uniprot id: A0A6J2LSE0
uniprot id: A0A7E6DTZ6
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

89673:CLTC
gene id: 89673:CLTC
uniprot id: A0A6J2ME63
uniprot id: A0A6J2MI17
uniprot id: A0A7E6EDL9
uniprot id: A0A7E6EDR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

89673:TNFSF13B
gene id: 89673:TNFSF13B
uniprot id: A0A6J2MQR5
names: Similarity
messages: Belongs to the tumor necrosis factor family.

89673:NHSL2
gene id: 89673:NHSL2
uniprot id: A0A7E6CZE9
names: Similarity
messages: Belongs to the NHS family.

89673:TCP11L2
gene id: 89673:TCP11L2
uniprot id: A0A6J2NGJ1
names: Similarity
messages: Belongs to the TCP11 family.

89673:LOC114500303
gene id: 89673:LOC114500303
uniprot id: A0A6J2LZI3
uniprot id: A0A7E6DWB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RAX2
gene id: 89673:RAX2
uniprot id: A0A6J2M4U2
uniprot id: A0A7E6EF63
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CRX.
messages: May be involved in modulating the expression of photoreceptor specific genes. Binds to the Ret-1 and Bat-1 element within the rhodopsin promoter.
messages: Nucleus

89673:PPP2R5A
gene id: 89673:PPP2R5A
uniprot id: A0A6J2N3D5
uniprot id: A0A7E6CWA4
uniprot id: A0A7E6CWK7
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

89673:MGRN1
gene id: 89673:MGRN1
uniprot id: A0A6J2LRC3
uniprot id: A0A6J2LUE9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

89673:PALM2AKAP2
gene id: 89673:PALM2AKAP2
uniprot id: A0A7E6DFV8
uniprot id: A0A7E6DFW6
uniprot id: A0A7E6DFX1
uniprot id: A0A7E6DFX5
uniprot id: A0A7E6DFY0
uniprot id: A0A7E6DG04
uniprot id: A0A7E6DG21
names: Similarity
messages: Belongs to the paralemmin family.

89673:LOC114500591
gene id: 89673:LOC114500591
uniprot id: A0A6J2M4Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114500328
gene id: 89673:LOC114500328
uniprot id: A0A6J2M414
names: Subcellular Location Annotation
messages: Secreted

89673:C5H10orf90
gene id: 89673:C5H10orf90
uniprot id: A0A6J2LVB8
names: Subcellular Location Annotation
messages: centrosome

89673:ADAM12
gene id: 89673:ADAM12
uniprot id: A0A7E6DW75
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:DUS4L
gene id: 89673:DUS4L
uniprot id: A0A6J2MP65
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

89673:LTB
gene id: 89673:LTB
uniprot id: A0A6J2LI94
names: Similarity
messages: Belongs to the tumor necrosis factor family.

89673:GTF2A1
gene id: 89673:GTF2A1
uniprot id: A0A6J2L5C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

89673:TIMM50
gene id: 89673:TIMM50
uniprot id: A0A6J2N7S3
uniprot id: A0A7E6CLD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

89673:TUBB3
gene id: 89673:TUBB3
uniprot id: A0A7E6CQR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

89673:LOC114489392
gene id: 89673:LOC114489392
uniprot id: A0A6J2L0Q6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:LOC114510510
gene id: 89673:LOC114510510
uniprot id: A0A7E6DAB0
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114499042
gene id: 89673:LOC114499042
uniprot id: A0A6J2LYA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HKDC1
gene id: 89673:HKDC1
uniprot id: A0A6J2LQW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

89673:LOC114491639
gene id: 89673:LOC114491639
uniprot id: A0A6J2L2A1
names: Similarity
messages: Belongs to the TMA7 family.

89673:LPCAT2
gene id: 89673:LPCAT2
uniprot id: A0A6J2KSX5
uniprot id: A0A7E6CNL4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

89673:LOC114488450
gene id: 89673:LOC114488450
uniprot id: A0A7E6CMH8
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

89673:NANOS2
gene id: 89673:NANOS2
uniprot id: A0A6J2N1Y6
names: Similarity
messages: Belongs to the nanos family.

89673:LOC114502581
gene id: 89673:LOC114502581
uniprot id: A0A6J2M7U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SEPTIN1
gene id: 89673:SEPTIN1
uniprot id: A0A7E6DDT1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

89673:GTPBP3
gene id: 89673:GTPBP3
uniprot id: A0A6J2MBI8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

89673:LMBR1L
gene id: 89673:LMBR1L
uniprot id: A0A7E6D6V5
names: Similarity
messages: Belongs to the LIMR family.

89673:SSTR1
gene id: 89673:SSTR1
uniprot id: A0A7E6E093
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:MED31
gene id: 89673:MED31
uniprot id: A0A6J2NJ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

89673:MRPL27
gene id: 89673:MRPL27
uniprot id: A0A6J2MBX7
uniprot id: A0A7E6EEA3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

89673:NEUROD6
gene id: 89673:NEUROD6
uniprot id: A0A6J2MVJ2
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

89673:UNC50
gene id: 89673:UNC50
uniprot id: A0A6J2M1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

89673:PARD6A
gene id: 89673:PARD6A
uniprot id: A0A6J2KQG4
uniprot id: A0A6J2KUF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

89673:TEKT4
gene id: 89673:TEKT4
uniprot id: A0A6J2N487
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

89673:TAF5L
gene id: 89673:TAF5L
uniprot id: A0A6J2NAJ0
uniprot id: A0A7E6CY91
uniprot id: A0A7E6CYM3
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

89673:TOR1B
gene id: 89673:TOR1B
uniprot id: A0A6J2M5Z3
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

89673:AMH
gene id: 89673:AMH
uniprot id: A0A6J2MDC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Plays an important role in several reproductive functions. Induces Muellerian duct regression during male fetal sexual differentiation and plays a role in Leydig cell differentiation and function. In female acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles. AMH signals by binding to a specific type-II receptor, AMHR2, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A), and recruiting SMAD proteins that are translocated to the nucleus to regulate target gene expression.
messages: Secreted

89673:METAP2
gene id: 89673:METAP2
uniprot id: A0A6J2N6N1
uniprot id: A0A6J2NBZ1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

89673:SEC62
gene id: 89673:SEC62
uniprot id: A0A6J2KZZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:TSC22D1
gene id: 89673:TSC22D1
uniprot id: A0A6J2MPY5
uniprot id: A0A6J2MWL3
uniprot id: A0A7E6CK36
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

89673:IMPACT
gene id: 89673:IMPACT
uniprot id: A0A6J2MMF4
uniprot id: A0A7E6CDL0
uniprot id: A0A7E6CDL2
uniprot id: A0A7E6CDP6
uniprot id: A0A7E6CEB7
uniprot id: A0A7E6CFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

89673:CCT6B
gene id: 89673:CCT6B
uniprot id: A0A6J2MB86
uniprot id: A0A7E6EEF1
uniprot id: A0A7E6EEY4
uniprot id: A0A7E6EF76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

89673:PDE1A
gene id: 89673:PDE1A
uniprot id: A0A6J2LH38
uniprot id: A0A7E6DJ69
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:LOC114489072
gene id: 89673:LOC114489072
uniprot id: A0A7E6CW29
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

89673:NUP58
gene id: 89673:NUP58
uniprot id: A0A6J2L1V2
uniprot id: A0A6J2L3P2
names: Subcellular Location Annotation
messages: nuclear pore complex

89673:FAM98A
gene id: 89673:FAM98A
uniprot id: A0A6J2LTW9
names: Similarity
messages: Belongs to the FAM98 family.

89673:COQ3
gene id: 89673:COQ3
uniprot id: A0A6J2LIH5
uniprot id: A0A7E6DMM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

89673:CD3G
gene id: 89673:CD3G
uniprot id: A0A7E6E051
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Membrane
messages: The TCR-CD3 complex is composed of a CD3D/CD3E and a CD3G/CD3E heterodimers that preferentially associate with TCRalpha and TCRbeta, respectively, to form TCRalpha/CD3E/CD3G and TCRbeta/CD3G/CD3E trimers. In turn, the hexamer interacts with CD3Z homodimer to form the TCR-CD3 complex. Alternatively, TCRalpha and TCRbeta can be replaced by TCRgamma and TCRdelta.

89673:DUSP26
gene id: 89673:DUSP26
uniprot id: A0A6J2MWQ4
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

89673:F9
gene id: 89673:F9
uniprot id: A0A6J2MH45
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:SLU7
gene id: 89673:SLU7
uniprot id: A0A6J2N441
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

89673:LOC114513461
gene id: 89673:LOC114513461
uniprot id: A0A6J2N9S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:EDN3
gene id: 89673:EDN3
uniprot id: A0A7E6CFZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

89673:LOC114498934
gene id: 89673:LOC114498934
uniprot id: A0A6J2LUN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CADM4
gene id: 89673:CADM4
uniprot id: A0A6J2N0V2
names: Similarity
messages: Belongs to the nectin family.

89673:LOC114508134
gene id: 89673:LOC114508134
uniprot id: A0A6J2MR12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PUS10
gene id: 89673:PUS10
uniprot id: A0A6J2M241
uniprot id: A0A7E6DXJ9
uniprot id: A0A7E6DXZ5
uniprot id: A0A7E6DYU4
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

89673:EIF4E2
gene id: 89673:EIF4E2
uniprot id: A0A6J2LBA4
uniprot id: A0A6J2LH39
uniprot id: A0A7E6DHT9
uniprot id: A0A7E6DHW1
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

89673:LOC114499082
gene id: 89673:LOC114499082
uniprot id: A0A6J2LYD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NHSL1
gene id: 89673:NHSL1
uniprot id: A0A7E6DNE3
uniprot id: A0A7E6DNH1
uniprot id: A0A7E6DP31
uniprot id: A0A7E6DPD5
names: Similarity
messages: Belongs to the NHS family.

89673:NACC1
gene id: 89673:NACC1
uniprot id: A0A6J2M9K9
names: Subcellular Location Annotation
messages: Nucleus

89673:APLNR
gene id: 89673:APLNR
uniprot id: A0A6J2M108
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:PHLDA2
gene id: 89673:PHLDA2
uniprot id: A0A6J2M374
names: Subcellular Location Annotation
messages: Cytoplasm

89673:SLC6A9
gene id: 89673:SLC6A9
uniprot id: A0A6J2LJG0
uniprot id: A0A6J2LPD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

89673:LOC114498754
gene id: 89673:LOC114498754
uniprot id: A0A7E6DWU6
names: Subcellular Location Annotation
messages: Nucleus

89673:RNF168
gene id: 89673:RNF168
uniprot id: A0A6J2L5H3
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to a well-established model, RNF168 cannot initiate H2A 'Lys-63'-linked ubiquitination and is recruited following RNF8-dependent histone ubiquitination to amplify H2A 'Lys-63'-linked ubiquitination. However, other data suggest that RNF168 is the priming ubiquitin ligase by mediating monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub respectively). These data suggest that RNF168 might be recruited to DSBs sites in a RNF8-dependent manner by binding to non-histone proteins ubiquitinated via 'Lys-63'-linked and initiates monoubiquitination of H2A, which is then amplified by RNF8. Additional evidences are however required to confirm these data.
messages: Belongs to the RNF168 family.
messages: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair. Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites. Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with UBE2N/UBC13.
messages: Nucleus
messages: Sumoylated with SUMO1 by PIAS4 in response to double-strand breaks (DSBs).
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).
messages: Ubiquitinated.

89673:PSEN2
gene id: 89673:PSEN2
uniprot id: A0A6J2N3B1
uniprot id: A0A6J2N9N1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

89673:LOC114510844
gene id: 89673:LOC114510844
uniprot id: A0A7E6CT62
names: Similarity
messages: Belongs to the MHC class I family.

89673:LPGAT1
gene id: 89673:LPGAT1
uniprot id: A0A6J2N495
uniprot id: A0A7E6CWS6
uniprot id: A0A7E6CX69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane

89673:PHF5A
gene id: 89673:PHF5A
uniprot id: A0A6J2N7K4
names: Similarity
messages: Belongs to the PHF5 family.

89673:UBIAD1
gene id: 89673:UBIAD1
uniprot id: A0A6J2LK88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

89673:LOC114503701
gene id: 89673:LOC114503701
uniprot id: A0A6J2MCV4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PCBD1
gene id: 89673:PCBD1
uniprot id: A0A6J2LP49
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

89673:POLA1
gene id: 89673:POLA1
uniprot id: A0A7E6D002
uniprot id: A0A7E6D005
uniprot id: A0A7E6D2S0
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

89673:CNTNAP4
gene id: 89673:CNTNAP4
uniprot id: A0A6J2KQB8
uniprot id: A0A7E6CMI1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TP53
gene id: 89673:TP53
uniprot id: A0A6J2NDA7
uniprot id: A0A7E6ED48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Mitochondrion matrix
messages: Nucleus
messages: PML body
messages: centrosome

89673:SEH1L
gene id: 89673:SEH1L
uniprot id: A0A6J2ML67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
messages: Lysosome membrane
messages: kinetochore

89673:RECQL
gene id: 89673:RECQL
uniprot id: A0A6J2N6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

89673:LOC114509847
gene id: 89673:LOC114509847
uniprot id: A0A6J2MX99
uniprot id: A0A7E6CS54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

89673:NUP85
gene id: 89673:NUP85
uniprot id: A0A6J2MCC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

89673:CENPV
gene id: 89673:CENPV
uniprot id: A0A6J2NEG3
uniprot id: A0A7E6EBV8
names: Similarity
messages: Belongs to the Gfa family.

89673:IAH1
gene id: 89673:IAH1
uniprot id: A0A6J2LZF5
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

89673:LOC114499008
gene id: 89673:LOC114499008
uniprot id: A0A6J2LSP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ISOC2
gene id: 89673:ISOC2
uniprot id: A0A6J2N5C6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isochorismatase family.
messages: Cytoplasm
messages: Interacts with CDKN2A.
messages: Nucleus

89673:LOC114505646
gene id: 89673:LOC114505646
uniprot id: A0A7E6D0Q0
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:TOR1A
gene id: 89673:TOR1A
uniprot id: A0A6J2LQ23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum lumen
messages: Homohexamer. Interacts with TOR1B; the interaction may be specific of neural tissues. Interacts (ATP-bound) with TOR1AIP1 and TOR1AIP2; the interactions induce ATPase activity. Interacts with KLHL14; preferentially when ATP-free. Interacts with KLC1 (via TPR repeats); the interaction associates TOR1A with the kinesin oligomeric complex. Interacts with COPS4; the interaction associates TOR1A with the CSN complex. Interacts with SNAPIN; the interaction is direct and associates SNAPIN with the CSN complex. Interacts with STON2. Interacts (ATP-bound) with SYNE3 (via KASH domain); the interaction is required for SYNE3 nuclear envelope localization. Interacts with VIM; the interaction associates TOR1A with the cytoskeleton. Interacts with PLEC. Interacts (ATP-bound) with SLC6A3; regulates SLC6A3 transport to the plasma membrane.
messages: Membrane
messages: growth cone

89673:MRPL2
gene id: 89673:MRPL2
uniprot id: A0A6J2LG61
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

89673:ACP1
gene id: 89673:ACP1
uniprot id: A0A6J2LWY1
uniprot id: A0A6J2M2E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

89673:ACSF3
gene id: 89673:ACSF3
uniprot id: A0A6J2KT54
uniprot id: A0A7E6CMY1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:MAP3K21
gene id: 89673:MAP3K21
uniprot id: A0A7E6CYV3
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

89673:RFLNB
gene id: 89673:RFLNB
uniprot id: A0A6J2M9V5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

89673:TEFM
gene id: 89673:TEFM
uniprot id: A0A7E6ECH3
uniprot id: A0A7E6EE11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEFM family.
messages: Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery.
messages: mitochondrion nucleoid

89673:PFKM
gene id: 89673:PFKM
uniprot id: A0A6J2N4X4
uniprot id: A0A6J2N6P3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114512472
gene id: 89673:LOC114512472
uniprot id: A0A6J2N3P8
uniprot id: A0A6J2N5V4
uniprot id: A0A7E6CYI3
uniprot id: A0A7E6CYM9
uniprot id: A0A7E6CYN3
uniprot id: A0A7E6CYZ1
uniprot id: A0A7E6CYZ6
uniprot id: A0A7E6CZG7
uniprot id: A0A7E6CZH2
uniprot id: A0A7E6D153
uniprot id: A0A7E6D158
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114506519
gene id: 89673:LOC114506519
uniprot id: A0A6J2MQ16
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

89673:FGF20
gene id: 89673:FGF20
uniprot id: A0A6J2MY07
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:AHCYL2
gene id: 89673:AHCYL2
uniprot id: A0A6J2MTQ7
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

89673:LOC114492309
gene id: 89673:LOC114492309
uniprot id: A0A7E6CK06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-5 subfamily.
messages: Nucleus

89673:PHACTR2
gene id: 89673:PHACTR2
uniprot id: A0A7E6DNH4
uniprot id: A0A7E6DNH9
uniprot id: A0A7E6DNJ2
uniprot id: A0A7E6DNJ4
uniprot id: A0A7E6DNZ2
uniprot id: A0A7E6DNZ9
uniprot id: A0A7E6DP68
uniprot id: A0A7E6DPH3
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

89673:CTNNA3
gene id: 89673:CTNNA3
uniprot id: A0A6J2LT92
uniprot id: A0A7E6DV76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: cytoskeleton

89673:TNKS2
gene id: 89673:TNKS2
uniprot id: A0A6J2LIA5
uniprot id: A0A7E6DUJ0
uniprot id: A0A7E6DV44
names: Function
names: Similarity
messages: Belongs to the ARTD/PARP family.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

89673:ERN2
gene id: 89673:ERN2
uniprot id: A0A7E6DAJ9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:CCNT2
gene id: 89673:CCNT2
uniprot id: A0A6J2LD13
uniprot id: A0A6J2LG08
names: Similarity
messages: Belongs to the cyclin family.

89673:SLC39A13
gene id: 89673:SLC39A13
uniprot id: A0A6J2LY83
uniprot id: A0A6J2LZB4
uniprot id: A0A6J2M079
uniprot id: A0A7E6E2K7
names: Subcellular Location Annotation
messages: Membrane

89673:SCGN
gene id: 89673:SCGN
uniprot id: A0A6J2KUT9
names: Subcellular Location Annotation
messages: secretory vesicle membrane

89673:GABRR1
gene id: 89673:GABRR1
uniprot id: A0A6J2LEE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:GEMIN2
gene id: 89673:GEMIN2
uniprot id: A0A6J2LC13
uniprot id: A0A7E6E045
uniprot id: A0A7E6E079
uniprot id: A0A7E6E196
uniprot id: A0A7E6E1B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

89673:SSH3
gene id: 89673:SSH3
uniprot id: A0A6J2LW15
uniprot id: A0A7E6E277
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

89673:LOC114490694
gene id: 89673:LOC114490694
uniprot id: A0A7E6D9X1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:CDKN1B
gene id: 89673:CDKN1B
uniprot id: A0A6J2N7F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDI family.
messages: Cytoplasm
messages: Endosome
messages: Nucleus

89673:PHKB
gene id: 89673:PHKB
uniprot id: A0A7E6CRF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

89673:PHETA1
gene id: 89673:PHETA1
uniprot id: A0A7E6CUC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

89673:HNRNPDL
gene id: 89673:HNRNPDL
uniprot id: A0A7E6DWQ9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:OPALIN
gene id: 89673:OPALIN
uniprot id: A0A6J2LNF3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
messages: Membrane

89673:GPRC5C
gene id: 89673:GPRC5C
uniprot id: A0A6J2MCE0
uniprot id: A0A7E6EEG0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:RAB27B
gene id: 89673:RAB27B
uniprot id: A0A6J2MPX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

89673:REEP4
gene id: 89673:REEP4
uniprot id: A0A6J2MBC3
uniprot id: A0A7E6EB74
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:CPA2
gene id: 89673:CPA2
uniprot id: A0A6J2MMP5
names: Similarity
messages: Belongs to the peptidase M14 family.

89673:NTS
gene id: 89673:NTS
uniprot id: A0A6J2NFY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

89673:ATP5F1E
gene id: 89673:ATP5F1E
uniprot id: A0A6J2MM84
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

89673:LOC114495322
gene id: 89673:LOC114495322
uniprot id: A0A7E6DC90
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114500261
gene id: 89673:LOC114500261
uniprot id: A0A6J2LZD7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TSPAN8
gene id: 89673:TSPAN8
uniprot id: A0A6J2NEA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:MMAA
gene id: 89673:MMAA
uniprot id: A0A6J2MCK7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

89673:PLK4
gene id: 89673:PLK4
uniprot id: A0A7E6E8K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: Cleavage furrow
messages: centriole

89673:CERS3
gene id: 89673:CERS3
uniprot id: A0A6J2KVV7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

89673:PRKCD
gene id: 89673:PRKCD
uniprot id: A0A6J2M4H8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression.
messages: Cytoplasm
messages: Interacts with PDPK1 (via N-terminal region), RAD9A, CDCP1, MUC1 and VASP.
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: perinuclear region

89673:MAPK3
gene id: 89673:MAPK3
uniprot id: A0A6J2LR87
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
messages: caveola

89673:AMDHD1
gene id: 89673:AMDHD1
uniprot id: A0A6J2NA73
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

89673:MYO16
gene id: 89673:MYO16
uniprot id: A0A7E6CK98
uniprot id: A0A7E6CKB5
uniprot id: A0A7E6CKC2
uniprot id: A0A7E6CMD5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:SLC12A9
gene id: 89673:SLC12A9
uniprot id: A0A6J2LK38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

89673:NAA11
gene id: 89673:NAA11
uniprot id: A0A6J2L8W0
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

89673:AQP11
gene id: 89673:AQP11
uniprot id: A0A6J2M2B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

89673:LOC114505108
gene id: 89673:LOC114505108
uniprot id: A0A6J2MHK8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:TSNAX
gene id: 89673:TSNAX
uniprot id: A0A6J2N3E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

89673:CLCN7
gene id: 89673:CLCN7
uniprot id: A0A6J2M949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

89673:LOC114491709
gene id: 89673:LOC114491709
uniprot id: A0A6J2L228
uniprot id: A0A6J2L2R6
uniprot id: A0A6J2L6F3
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

89673:DNASE2B
gene id: 89673:DNASE2B
uniprot id: A0A6J2LRG4
uniprot id: A0A7E6DSR1
uniprot id: A0A7E6DTC9
names: Similarity
messages: Belongs to the DNase II family.

89673:TP53RK
gene id: 89673:TP53RK
uniprot id: A0A6J2MM26
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

89673:PGM3
gene id: 89673:PGM3
uniprot id: A0A6J2LE50
uniprot id: A0A7E6DMD5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

89673:MGAT1
gene id: 89673:MGAT1
uniprot id: A0A6J2MW76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

89673:CAVIN2
gene id: 89673:CAVIN2
uniprot id: A0A6J2LGE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

89673:UNC5D
gene id: 89673:UNC5D
uniprot id: A0A7E6CJA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

89673:LOC114513621
gene id: 89673:LOC114513621
uniprot id: A0A6J2NAD3
uniprot id: A0A6J2NFW0
uniprot id: A0A7E6D5S2
uniprot id: A0A7E6D8I2
names: Similarity
messages: Belongs to the SEC2 family.

89673:FCHO2
gene id: 89673:FCHO2
uniprot id: A0A6J2LJ35
uniprot id: A0A7E6DAC6
uniprot id: A0A7E6DAG1
uniprot id: A0A7E6DAQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FCHO family.
messages: clathrin-coated pit

89673:SDR16C5
gene id: 89673:SDR16C5
uniprot id: A0A6J2NDG7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:POU6F1
gene id: 89673:POU6F1
uniprot id: A0A6J2NHA1
uniprot id: A0A7E6D6N0
uniprot id: A0A7E6D6N3
uniprot id: A0A7E6D9I0
uniprot id: A0A7E6D9I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

89673:PPAT
gene id: 89673:PPAT
uniprot id: A0A6J2L4Y7
uniprot id: A0A7E6DC92
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

89673:GALNTL5
gene id: 89673:GALNTL5
uniprot id: A0A6J2MV54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Membrane

89673:TRMT6
gene id: 89673:TRMT6
uniprot id: A0A6J2MQP1
uniprot id: A0A7E6CEQ1
uniprot id: A0A7E6CFD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

89673:CACNA2D3
gene id: 89673:CACNA2D3
uniprot id: A0A6J2M5U4
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

89673:CLDN3
gene id: 89673:CLDN3
uniprot id: A0A6J2LVA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:ATP6V1A
gene id: 89673:ATP6V1A
uniprot id: A0A6J2KZ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: clathrin-coated vesicle membrane
messages: secretory vesicle

89673:FZD5
gene id: 89673:FZD5
uniprot id: A0A6J2LFT1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TRPV4
gene id: 89673:TRPV4
uniprot id: A0A6J2N3R1
names: Subcellular Location Annotation
messages: Membrane

89673:QARS1
gene id: 89673:QARS1
uniprot id: A0A6J2M3S2
uniprot id: A0A7E6E4K0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

89673:LOC114493322
gene id: 89673:LOC114493322
uniprot id: A0A6J2LA29
names: Similarity
messages: Belongs to the serpin family.

89673:CASP14
gene id: 89673:CASP14
uniprot id: A0A6J2M4A5
names: Similarity
messages: Belongs to the peptidase C14A family.

89673:PLEC
gene id: 89673:PLEC
uniprot id: A0A6J2NAJ6
uniprot id: A0A6J2NC76
uniprot id: A0A6J2NCF3
uniprot id: A0A6J2NCF8
uniprot id: A0A6J2NHC8
uniprot id: A0A6J2NI04
uniprot id: A0A6J2NI08
uniprot id: A0A7E6E785
uniprot id: A0A7E6E790
uniprot id: A0A7E6E795
uniprot id: A0A7E6E7S8
uniprot id: A0A7E6E7T5
uniprot id: A0A7E6E847
uniprot id: A0A7E6E853
uniprot id: A0A7E6E8Q7
uniprot id: A0A7E6E8R4
uniprot id: A0A7E6E918
uniprot id: A0A7E6E923
uniprot id: A0A7E6E930
names: Subcellular Location Annotation
messages: cytoskeleton

89673:LOC114498927
gene id: 89673:LOC114498927
uniprot id: A0A6J2LSJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SETD1B
gene id: 89673:SETD1B
uniprot id: A0A6J2MVC8
uniprot id: A0A7E6CTP8
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

89673:DNASE1L3
gene id: 89673:DNASE1L3
uniprot id: A0A6J2M335
names: Similarity
messages: Belongs to the DNase I family.

89673:PDE4C
gene id: 89673:PDE4C
uniprot id: A0A6J2MAM2
uniprot id: A0A7E6E9Y3
uniprot id: A0A7E6EAR6
uniprot id: A0A7E6EC05
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:TUBG1
gene id: 89673:TUBG1
uniprot id: A0A6J2MAX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
messages: centrosome

89673:SMC3
gene id: 89673:SMC3
uniprot id: A0A6J2LJN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

89673:FBP1
gene id: 89673:FBP1
uniprot id: A0A6J2N622
names: Similarity
messages: Belongs to the FBPase class 1 family.

89673:WNT10B
gene id: 89673:WNT10B
uniprot id: A0A6J2NBE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:LOC114506934
gene id: 89673:LOC114506934
uniprot id: A0A6J2MML2
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

89673:YWHAQ
gene id: 89673:YWHAQ
uniprot id: A0A6J2LYV1
names: Function
names: Similarity
messages: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
messages: Belongs to the 14-3-3 family.

89673:LOC114503444
gene id: 89673:LOC114503444
uniprot id: A0A6J2MC46
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:LOC114508060
gene id: 89673:LOC114508060
uniprot id: A0A6J2MQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TNFSF10
gene id: 89673:TNFSF10
uniprot id: A0A7E6D2W5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Homotrimer.
messages: Membrane
messages: Secreted

89673:LOC114497505
gene id: 89673:LOC114497505
uniprot id: A0A6J2LT47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

89673:CDC6
gene id: 89673:CDC6
uniprot id: A0A6J2M9E7
uniprot id: A0A7E6EFL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
messages: Nucleus

89673:SOX12
gene id: 89673:SOX12
uniprot id: A0A7E6CF01
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114503355
gene id: 89673:LOC114503355
uniprot id: A0A6J2MEG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PNLIPRP1
gene id: 89673:PNLIPRP1
uniprot id: A0A6J2LKG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

89673:LOC114508228
gene id: 89673:LOC114508228
uniprot id: A0A6J2MPD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ADRA1D
gene id: 89673:ADRA1D
uniprot id: A0A6J2MQC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

89673:FMN1
gene id: 89673:FMN1
uniprot id: A0A7E6D1G2
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

89673:LOC114489204
gene id: 89673:LOC114489204
uniprot id: A0A6J2KWH1
names: Similarity
messages: Belongs to the peptidase A1 family.

89673:WNT16
gene id: 89673:WNT16
uniprot id: A0A6J2MQ43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:COPS4
gene id: 89673:COPS4
uniprot id: A0A6J2L3U1
uniprot id: A0A6J2L644
uniprot id: A0A7E6DWG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Cytoplasm
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

89673:LOC114503347
gene id: 89673:LOC114503347
uniprot id: A0A6J2MBI0
uniprot id: A0A7E6EFE3
uniprot id: A0A7E6EG91
uniprot id: A0A7E6EGZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

89673:FAM167A
gene id: 89673:FAM167A
uniprot id: A0A6J2MAN3
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

89673:TBL1XR1
gene id: 89673:TBL1XR1
uniprot id: A0A6J2KZ72
uniprot id: A0A7E6D3K1
names: Similarity
messages: Belongs to the WD repeat EBI family.

89673:HAX1
gene id: 89673:HAX1
uniprot id: A0A6J2KU58
uniprot id: A0A7E6CW47
uniprot id: A0A7E6CW92
uniprot id: A0A7E6CWL4
names: Function
names: Similarity
messages: Belongs to the HAX1 family.
messages: Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.

89673:TAFA4
gene id: 89673:TAFA4
uniprot id: A0A7E6E845
names: Similarity
messages: Belongs to the TAFA family.

89673:HNRNPAB
gene id: 89673:HNRNPAB
uniprot id: A0A6J2MRX6
uniprot id: A0A7E6CSE7
uniprot id: A0A7E6CSE8
uniprot id: A0A7E6CSV5
uniprot id: A0A7E6CSW2
uniprot id: A0A7E6CT38
uniprot id: A0A7E6CT43
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:CALU
gene id: 89673:CALU
uniprot id: A0A6J2MPB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus
messages: Melanosome
messages: Membrane
messages: Sarcoplasmic reticulum lumen
messages: Secreted

89673:PAIP2
gene id: 89673:PAIP2
uniprot id: A0A6J2MZG9
names: Similarity
messages: Belongs to the PAIP2 family.

89673:TMEM182
gene id: 89673:TMEM182
uniprot id: A0A6J2M572
uniprot id: A0A7E6DYH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

89673:TMEM121
gene id: 89673:TMEM121
uniprot id: A0A6J2L7W8
names: Similarity
messages: Belongs to the TMEM121 family.

89673:AKAP8
gene id: 89673:AKAP8
uniprot id: A0A6J2MAJ5
uniprot id: A0A7E6E9N8
uniprot id: A0A7E6EAG8
uniprot id: A0A7E6EAN7
uniprot id: A0A7E6EBB4
uniprot id: A0A7E6EBN7
names: Similarity
messages: Belongs to the AKAP95 family.

89673:CARM1
gene id: 89673:CARM1
uniprot id: A0A6J2M4C0
uniprot id: A0A7E6EAX5
names: Subcellular Location Annotation
messages: Nucleus

89673:PEX10
gene id: 89673:PEX10
uniprot id: A0A6J2LIB9
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

89673:LOC118501458
gene id: 89673:LOC118501458
uniprot id: A0A7E6E3H9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:MEN1
gene id: 89673:MEN1
uniprot id: A0A6J2LZC2
uniprot id: A0A7E6E224
names: Subcellular Location Annotation
messages: Nucleus

89673:MIGA2
gene id: 89673:MIGA2
uniprot id: A0A6J2LTK5
names: Similarity
messages: Belongs to the mitoguardin family.

89673:PRDM13
gene id: 89673:PRDM13
uniprot id: A0A6J2LF52
uniprot id: A0A7E6DNH7
names: Subcellular Location Annotation
messages: Nucleus

89673:ASZ1
gene id: 89673:ASZ1
uniprot id: A0A6J2MV41
uniprot id: A0A7E6CIG3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

89673:MED11
gene id: 89673:MED11
uniprot id: A0A6J2NJ71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

89673:ATIC
gene id: 89673:ATIC
uniprot id: A0A6J2LCT9
names: Similarity
messages: Belongs to the PurH family.

89673:LIG4
gene id: 89673:LIG4
uniprot id: A0A6J2MWU8
uniprot id: A0A7E6CKB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

89673:PPP2R5C
gene id: 89673:PPP2R5C
uniprot id: A0A6J2L7P2
uniprot id: A0A6J2LD12
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

89673:LOC114500760
gene id: 89673:LOC114500760
uniprot id: A0A6J2M505
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

89673:PPFIA4
gene id: 89673:PPFIA4
uniprot id: A0A6J2N3A0
uniprot id: A0A6J2NAG8
uniprot id: A0A7E6CY25
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

89673:CRYBB2
gene id: 89673:CRYBB2
uniprot id: A0A6J2N2Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

89673:RSPO2
gene id: 89673:RSPO2
uniprot id: A0A6J2NAI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

89673:GIMAP6
gene id: 89673:GIMAP6
uniprot id: A0A6J2MPX2
uniprot id: A0A7E6CJ06
uniprot id: A0A7E6CJ57
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:SEPTIN8
gene id: 89673:SEPTIN8
uniprot id: A0A6J2MS50
uniprot id: A0A6J2MTU2
uniprot id: A0A6J2MTU5
uniprot id: A0A6J2MYD6
uniprot id: A0A7E6CU02
uniprot id: A0A7E6CUJ4
uniprot id: A0A7E6CUR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Presynapse
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: synaptic vesicle membrane

89673:FMOD
gene id: 89673:FMOD
uniprot id: A0A6J2N3Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to type I and type II collagen.
messages: extracellular matrix

89673:FSCN3
gene id: 89673:FSCN3
uniprot id: A0A6J2MQU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

89673:LOC114509095
gene id: 89673:LOC114509095
uniprot id: A0A6J2MS34
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:HDGFL2
gene id: 89673:HDGFL2
uniprot id: A0A6J2MAE7
uniprot id: A0A6J2MDP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

89673:ACTG2
gene id: 89673:ACTG2
uniprot id: A0A6J2LX38
names: Similarity
messages: Belongs to the actin family.

89673:GJD4
gene id: 89673:GJD4
uniprot id: A0A6J2L1E4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:CAMK2G
gene id: 89673:CAMK2G
uniprot id: A0A6J2LNM7
uniprot id: A0A6J2LNN2
uniprot id: A0A6J2LNN7
uniprot id: A0A6J2LPX6
uniprot id: A0A6J2LPY0
uniprot id: A0A6J2LPY4
uniprot id: A0A6J2LQU9
uniprot id: A0A6J2LQV4
uniprot id: A0A6J2LQW0
uniprot id: A0A6J2LTX0
uniprot id: A0A6J2LTX7
uniprot id: A0A6J2LU16
uniprot id: A0A6J2LU21
uniprot id: A0A6J2LU30
uniprot id: A0A7E6DTY4
uniprot id: A0A7E6DU30
uniprot id: A0A7E6DU35
uniprot id: A0A7E6DUJ6
uniprot id: A0A7E6DUV9
uniprot id: A0A7E6DV78
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

89673:PLAGL2
gene id: 89673:PLAGL2
uniprot id: A0A6J2MHW8
uniprot id: A0A6J2MK19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

89673:MCM4
gene id: 89673:MCM4
uniprot id: A0A6J2M6V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

89673:STOML1
gene id: 89673:STOML1
uniprot id: A0A6J2L5A2
uniprot id: A0A6J2L5A7
uniprot id: A0A7E6DXS1
uniprot id: A0A7E6DYP7
uniprot id: A0A7E6DYQ6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

89673:RCAN3
gene id: 89673:RCAN3
uniprot id: A0A6J2LQL5
names: Similarity
messages: Belongs to the RCAN family.

89673:F2RL3
gene id: 89673:F2RL3
uniprot id: A0A6J2MEH6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:LOC114491765
gene id: 89673:LOC114491765
uniprot id: A0A6J2L4M5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:OPLAH
gene id: 89673:OPLAH
uniprot id: A0A6J2NC85
uniprot id: A0A7E6E7V3
names: Similarity
messages: Belongs to the oxoprolinase family.

89673:HOXD1
gene id: 89673:HOXD1
uniprot id: A0A6J2LE10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

89673:SMARCA1
gene id: 89673:SMARCA1
uniprot id: A0A6J2MF52
uniprot id: A0A6J2MID3
uniprot id: A0A6J2MJ20
uniprot id: A0A7E6D0H3
uniprot id: A0A7E6D0J3
uniprot id: A0A7E6D0Q6
uniprot id: A0A7E6D1E7
uniprot id: A0A7E6D3B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

89673:DYNC2LI1
gene id: 89673:DYNC2LI1
uniprot id: A0A6J2LY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

89673:EML2
gene id: 89673:EML2
uniprot id: A0A6J2N016
uniprot id: A0A6J2N021
uniprot id: A0A6J2N1R2
uniprot id: A0A6J2N6D2
uniprot id: A0A6J2N770
uniprot id: A0A7E6CPN5
uniprot id: A0A7E6CPU4
uniprot id: A0A7E6CPY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EMAP family.
messages: cytoskeleton

89673:LOC114499482
gene id: 89673:LOC114499482
uniprot id: A0A7E6E0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

89673:SDHD
gene id: 89673:SDHD
uniprot id: A0A6J2LRL3
uniprot id: A0A6J2LWP1
uniprot id: A0A7E6DZJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

89673:CXCR6
gene id: 89673:CXCR6
uniprot id: A0A6J2M8X2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:FAM120B
gene id: 89673:FAM120B
uniprot id: A0A6J2L0I2
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

89673:TRAPPC2L
gene id: 89673:TRAPPC2L
uniprot id: A0A6J2KQL3
uniprot id: A0A7E6CQC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

89673:EPHB1
gene id: 89673:EPHB1
uniprot id: A0A6J2M369
uniprot id: A0A7E6E6F9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: dendrite

89673:LOC114505488
gene id: 89673:LOC114505488
uniprot id: A0A7E6D1L0
names: Subcellular Location Annotation
messages: Nucleus

89673:ARHGEF28
gene id: 89673:ARHGEF28
uniprot id: A0A7E6DAR8
names: Subcellular Location Annotation
messages: Cytoplasm

89673:SF3B1
gene id: 89673:SF3B1
uniprot id: A0A6J2LAA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

89673:GAL3ST3
gene id: 89673:GAL3ST3
uniprot id: A0A7E6E2N3
uniprot id: A0A7E6E2U4
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

89673:FMNL1
gene id: 89673:FMNL1
uniprot id: A0A6J2MA90
uniprot id: A0A7E6EEB8
uniprot id: A0A7E6EEC2
uniprot id: A0A7E6EEV5
uniprot id: A0A7E6EEW0
uniprot id: A0A7E6EF45
uniprot id: A0A7E6EFX3
uniprot id: A0A7E6EG29
uniprot id: A0A7E6EG33
names: Similarity
messages: Belongs to the formin homology family.

89673:RNASE1
gene id: 89673:RNASE1
uniprot id: A0A6J2KXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

89673:ELOC
gene id: 89673:ELOC
uniprot id: A0A6J2M4E5
names: Similarity
messages: Belongs to the SKP1 family.

89673:SLC23A1
gene id: 89673:SLC23A1
uniprot id: A0A6J2N3W7
uniprot id: A0A7E6CUW7
uniprot id: A0A7E6CV59
names: Subcellular Location Annotation
messages: Membrane

89673:HAT1
gene id: 89673:HAT1
uniprot id: A0A6J2LGT2
uniprot id: A0A6J2LK58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

89673:LOC118496652
gene id: 89673:LOC118496652
uniprot id: A0A6J2L333
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SNX33
gene id: 89673:SNX33
uniprot id: A0A6J2L2G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

89673:YDJC
gene id: 89673:YDJC
uniprot id: A0A6J2N1X6
names: Function
names: Similarity
messages: Belongs to the YdjC deacetylase family.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

89673:CEP170
gene id: 89673:CEP170
uniprot id: A0A6J2N363
uniprot id: A0A6J2N4X0
uniprot id: A0A6J2N9H4
uniprot id: A0A7E6CYA3
uniprot id: A0A7E6CYA7
uniprot id: A0A7E6CYF3
uniprot id: A0A7E6CYQ8
uniprot id: A0A7E6CYR3
uniprot id: A0A7E6CZ80
uniprot id: A0A7E6D0X7
uniprot id: A0A7E6D0Y2
names: Similarity
messages: Belongs to the CEP170 family.

89673:MTMR1
gene id: 89673:MTMR1
uniprot id: A0A6J2MG34
uniprot id: A0A6J2MJC7
uniprot id: A0A7E6CYM0
uniprot id: A0A7E6CYM5
uniprot id: A0A7E6CYN0
uniprot id: A0A7E6CYS4
uniprot id: A0A7E6CYS9
uniprot id: A0A7E6CZ41
uniprot id: A0A7E6CZ45
uniprot id: A0A7E6CZ49
uniprot id: A0A7E6CZK3
uniprot id: A0A7E6CZK8
uniprot id: A0A7E6CZL3
uniprot id: A0A7E6D1B9
uniprot id: A0A7E6D1C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

89673:PPP6R1
gene id: 89673:PPP6R1
uniprot id: A0A6J2N2K9
uniprot id: A0A6J2N773
uniprot id: A0A7E6CNX7
uniprot id: A0A7E6CNZ5
names: Similarity
messages: Belongs to the SAPS family.

89673:XPA
gene id: 89673:XPA
uniprot id: A0A6J2M8N7
uniprot id: A0A7E6DFP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

89673:ADORA2B
gene id: 89673:ADORA2B
uniprot id: A0A6J2NCG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

89673:DIPK1C
gene id: 89673:DIPK1C
uniprot id: A0A6J2MMX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

89673:KIF3C
gene id: 89673:KIF3C
uniprot id: A0A6J2LW34
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:SPAG9
gene id: 89673:SPAG9
uniprot id: A0A6J2MEY2
uniprot id: A0A6J2MEZ4
uniprot id: A0A6J2MI22
uniprot id: A0A7E6EDF7
uniprot id: A0A7E6EE15
uniprot id: A0A7E6EF80
names: Similarity
messages: Belongs to the JIP scaffold family.

89673:C7
gene id: 89673:C7
uniprot id: A0A6J2MIR0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:EMC9
gene id: 89673:EMC9
uniprot id: A0A6J2L529
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

89673:LOC114503307
gene id: 89673:LOC114503307
uniprot id: A0A6J2ME93
names: Function
names: Subcellular Location Annotation
messages: Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
messages: extracellular matrix

89673:SPRY1
gene id: 89673:SPRY1
uniprot id: A0A7E6E8R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: Cytoplasm
messages: Membrane

89673:OVOL1
gene id: 89673:OVOL1
uniprot id: A0A6J2LYM7
names: Subcellular Location Annotation
messages: Nucleus

89673:WNT7B
gene id: 89673:WNT7B
uniprot id: A0A6J2N911
uniprot id: A0A6J2NE19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:GALNTL6
gene id: 89673:GALNTL6
uniprot id: A0A6J2MAH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:CAPN15
gene id: 89673:CAPN15
uniprot id: A0A6J2LQ82
uniprot id: A0A6J2LQ91
uniprot id: A0A7E6DCX2
uniprot id: A0A7E6DD87
names: Similarity
messages: Belongs to the peptidase C2 family.

89673:SUPT4H1
gene id: 89673:SUPT4H1
uniprot id: A0A6J2MCG3
uniprot id: A0A7E6ED98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

89673:EMC6
gene id: 89673:EMC6
uniprot id: A0A6J2NC41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:APLP1
gene id: 89673:APLP1
uniprot id: A0A6J2MYY6
uniprot id: A0A6J2N0N3
uniprot id: A0A6J2N5B9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:CCN2
gene id: 89673:CCN2
uniprot id: A0A7E6DNY0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:FLCN
gene id: 89673:FLCN
uniprot id: A0A7E6EBK9
uniprot id: A0A7E6EBL3
uniprot id: A0A7E6EBN6
uniprot id: A0A7E6ECC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

89673:SPARC
gene id: 89673:SPARC
uniprot id: A0A6J2MV73
uniprot id: A0A6J2MWX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

89673:BCL7B
gene id: 89673:BCL7B
uniprot id: A0A6J2M008
names: Similarity
messages: Belongs to the BCL7 family.

89673:DNMT3L
gene id: 89673:DNMT3L
uniprot id: A0A6J2KZD1
names: Subcellular Location Annotation
messages: Nucleus

89673:SPCS3
gene id: 89673:SPCS3
uniprot id: A0A6J2MWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

89673:TMEM19
gene id: 89673:TMEM19
uniprot id: A0A6J2NFN5
uniprot id: A0A7E6D6B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

89673:LOC114499991
gene id: 89673:LOC114499991
uniprot id: A0A6J2LYE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

89673:UFD1
gene id: 89673:UFD1
uniprot id: A0A6J2N225
uniprot id: A0A7E6CUJ9
names: Similarity
messages: Belongs to the UFD1 family.

89673:PSMG2
gene id: 89673:PSMG2
uniprot id: A0A6J2MKW3
uniprot id: A0A7E6CE10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

89673:CD36
gene id: 89673:CD36
uniprot id: A0A6J2MTS8
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the CD36 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: Membrane raft

89673:SYNE3
gene id: 89673:SYNE3
uniprot id: A0A7E6CRK1
uniprot id: A0A7E6CRX2
names: Similarity
messages: Belongs to the nesprin family.

89673:TSHZ1
gene id: 89673:TSHZ1
uniprot id: A0A7E6CGV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

89673:LOC114499796
gene id: 89673:LOC114499796
uniprot id: A0A6J2LXJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RBL1
gene id: 89673:RBL1
uniprot id: A0A6J2MID0
uniprot id: A0A7E6CFE2
uniprot id: A0A7E6CG04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

89673:LOC114495081
gene id: 89673:LOC114495081
uniprot id: A0A7E6DN28
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

89673:LOC114504890
gene id: 89673:LOC114504890
uniprot id: A0A6J2MK45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

89673:TMEM121B
gene id: 89673:TMEM121B
uniprot id: A0A6J2MY57
names: Similarity
messages: Belongs to the TMEM121 family.

89673:FABP6
gene id: 89673:FABP6
uniprot id: A0A6J2MWX5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

89673:CHRNA4
gene id: 89673:CHRNA4
uniprot id: A0A6J2MLY1
uniprot id: A0A7E6CGB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:PAPPA2
gene id: 89673:PAPPA2
uniprot id: A0A6J2N907
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SUGCT
gene id: 89673:SUGCT
uniprot id: A0A6J2MQQ7
names: Similarity
messages: Belongs to the CoA-transferase III family.

89673:ACO2
gene id: 89673:ACO2
uniprot id: A0A6J2NCQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

89673:MAP4K2
gene id: 89673:MAP4K2
uniprot id: A0A6J2LZP0
uniprot id: A0A7E6E2L1
uniprot id: A0A7E6E2S5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

89673:SIX4
gene id: 89673:SIX4
uniprot id: A0A6J2LAA7
uniprot id: A0A6J2LE85
names: Subcellular Location Annotation
messages: Nucleus

89673:FBLL1
gene id: 89673:FBLL1
uniprot id: A0A6J2N1D0
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

89673:MAGOH
gene id: 89673:MAGOH
uniprot id: A0A6J2LMS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

89673:RPL30
gene id: 89673:RPL30
uniprot id: A0A6J2NAF5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

89673:LOC114509927
gene id: 89673:LOC114509927
uniprot id: A0A6J2MXL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DDX6
gene id: 89673:DDX6
uniprot id: A0A6J2M3Y5
names: Similarity
messages: Belongs to the DEAD box helicase family.

89673:SLC9A3R1
gene id: 89673:SLC9A3R1
uniprot id: A0A6J2MBP0
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.
messages: filopodium
messages: microvillus
messages: ruffle

89673:HMGCS1
gene id: 89673:HMGCS1
uniprot id: A0A6J2LZV2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

89673:API5
gene id: 89673:API5
uniprot id: A0A6J2LRW0
uniprot id: A0A6J2LT67
names: Similarity
messages: Belongs to the API5 family.

89673:LOC114490272
gene id: 89673:LOC114490272
uniprot id: A0A6J2KZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

89673:LOC114500428
gene id: 89673:LOC114500428
uniprot id: A0A6J2M015
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TCAF2
gene id: 89673:TCAF2
uniprot id: A0A6J2MPC4
names: Similarity
messages: Belongs to the TCAF family.

89673:ATG12
gene id: 89673:ATG12
uniprot id: A0A6J2MSE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Ubiquitin-like protein involved in autophagic vesicle formation.

89673:TNFRSF25
gene id: 89673:TNFRSF25
uniprot id: A0A7E6DPT2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SPIN4
gene id: 89673:SPIN4
uniprot id: A0A6J2ML04
names: Similarity
messages: Belongs to the SPIN/STSY family.

89673:LOC114489249
gene id: 89673:LOC114489249
uniprot id: A0A7E6CYW0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:SDC1
gene id: 89673:SDC1
uniprot id: A0A6J2LWD4
uniprot id: A0A7E6DWM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane
messages: extracellular exosome

89673:LOC114508064
gene id: 89673:LOC114508064
uniprot id: A0A6J2MNU3
uniprot id: A0A6J2MQS8
uniprot id: A0A6J2MV74
uniprot id: A0A6J2MVI4
uniprot id: A0A7E6CIP1
names: Similarity
messages: Belongs to the Luc7 family.

89673:MTERF2
gene id: 89673:MTERF2
uniprot id: A0A6J2NFG0
names: Similarity
messages: Belongs to the mTERF family.

89673:FURIN
gene id: 89673:FURIN
uniprot id: A0A6J2KS00
names: Similarity
messages: Belongs to the peptidase S8 family.

89673:LOC114500611
gene id: 89673:LOC114500611
uniprot id: A0A7E6E0V1
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

89673:CCDC85B
gene id: 89673:CCDC85B
uniprot id: A0A6J2M1L4
uniprot id: A0A7E6E506
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

89673:HSPA4L
gene id: 89673:HSPA4L
uniprot id: A0A6J2M6P6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

89673:CLDN7
gene id: 89673:CLDN7
uniprot id: A0A6J2NJ67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:HOXA11
gene id: 89673:HOXA11
uniprot id: A0A6J2MPG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

89673:DLX2
gene id: 89673:DLX2
uniprot id: A0A6J2LF98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

89673:SEMA6D
gene id: 89673:SEMA6D
uniprot id: A0A6J2L205
uniprot id: A0A6J2L2P3
uniprot id: A0A6J2L2P7
uniprot id: A0A6J2L4A9
uniprot id: A0A6J2L6C3
uniprot id: A0A6J2L6C8
uniprot id: A0A6J2L7P3
uniprot id: A0A7E6EC92
uniprot id: A0A7E6ED67
uniprot id: A0A7E6EDC5
uniprot id: A0A7E6EDF1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RPL26L1
gene id: 89673:RPL26L1
uniprot id: A0A6J2N103
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

89673:SLC41A1
gene id: 89673:SLC41A1
uniprot id: A0A6J2N859
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

89673:GBX1
gene id: 89673:GBX1
uniprot id: A0A6J2MPA5
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114503694
gene id: 89673:LOC114503694
uniprot id: A0A7E6EFK4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC118501461
gene id: 89673:LOC118501461
uniprot id: A0A7E6E3N0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114507300
gene id: 89673:LOC114507300
uniprot id: A0A6J2MSQ3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

89673:TCEANC
gene id: 89673:TCEANC
uniprot id: A0A6J2MLN5
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114513176
gene id: 89673:LOC114513176
uniprot id: A0A7E6D9G6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion matrix
messages: Monomer.

89673:SHBG
gene id: 89673:SHBG
uniprot id: A0A6J2NJN4
uniprot id: A0A7E6EDD6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114500614
gene id: 89673:LOC114500614
uniprot id: A0A6J2M4G9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114490182
gene id: 89673:LOC114490182
uniprot id: A0A6J2KZ48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ARR3
gene id: 89673:ARR3
uniprot id: A0A7E6D1L3
names: Function
names: Similarity
messages: Belongs to the arrestin family.
messages: May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins.

89673:EP300
gene id: 89673:EP300
uniprot id: A0A6J2N7F7
names: Subcellular Location Annotation
messages: Cytoplasm

89673:RPL4
gene id: 89673:RPL4
uniprot id: A0A6J2L823
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

89673:PRODH2
gene id: 89673:PRODH2
uniprot id: A0A6J2N1H4
uniprot id: A0A7E6CMJ6
uniprot id: A0A7E6CMP3
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

89673:PSD
gene id: 89673:PSD
uniprot id: A0A6J2LK01
names: Subcellular Location Annotation
messages: ruffle membrane

89673:DGKQ
gene id: 89673:DGKQ
uniprot id: A0A7E6D366
uniprot id: A0A7E6D3A8
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

89673:ERRFI1
gene id: 89673:ERRFI1
uniprot id: A0A6J2LS75
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

89673:CSTB
gene id: 89673:CSTB
uniprot id: A0A6J2L2H7
names: Similarity
messages: Belongs to the cystatin family.

89673:CASTOR1
gene id: 89673:CASTOR1
uniprot id: A0A6J2MV88
uniprot id: A0A7E6CST8
uniprot id: A0A7E6CTA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GATS family.
messages: cytosol

89673:NAA38
gene id: 89673:NAA38
uniprot id: A0A6J2NF65
uniprot id: A0A7E6EBF9
uniprot id: A0A7E6EC82
names: Function
names: Similarity
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

89673:TBX4
gene id: 89673:TBX4
uniprot id: A0A6J2M7C8
uniprot id: A0A6J2MC17
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:NDUFV3
gene id: 89673:NDUFV3
uniprot id: A0A6J2L1L5
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

89673:GJA10
gene id: 89673:GJA10
uniprot id: A0A6J2LI92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:LOC114490380
gene id: 89673:LOC114490380
uniprot id: A0A6J2L3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

89673:LOC114513878
gene id: 89673:LOC114513878
uniprot id: A0A6J2N969
uniprot id: A0A7E6D7Q8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:CTSW
gene id: 89673:CTSW
uniprot id: A0A7E6E501
names: Similarity
messages: Belongs to the peptidase C1 family.

89673:DRC7
gene id: 89673:DRC7
uniprot id: A0A6J2KT31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC7 family.
messages: cilium axoneme
messages: flagellum
messages: flagellum axoneme

89673:LOC114492156
gene id: 89673:LOC114492156
uniprot id: A0A7E6D294
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the centrosome.

89673:SLC24A2
gene id: 89673:SLC24A2
uniprot id: A0A6J2MKX1
uniprot id: A0A6J2MMV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

89673:LOC114496244
gene id: 89673:LOC114496244
uniprot id: A0A6J2LHS4
uniprot id: A0A6J2LMQ3
uniprot id: A0A6J2LNG6
names: Subcellular Location Annotation
messages: Secreted

89673:C1R
gene id: 89673:C1R
uniprot id: A0A6J2NAP7
names: Caution
names: Function
names: Subunit
messages: C1 is a calcium-dependent trimolecular complex of C1q, C1r and C1s in the molar ration of 1:2:2. C1r is a dimer of identical chains, each of which is activated by cleavage into two chains, A and B, connected by disulfide bonds.
messages: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CDH1
gene id: 89673:CDH1
uniprot id: A0A6J2KQM2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
messages: Membrane
messages: trans-Golgi network

89673:LOC114508689
gene id: 89673:LOC114508689
uniprot id: A0A6J2MSJ4
uniprot id: A0A7E6CJQ8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

89673:TENT5C
gene id: 89673:TENT5C
uniprot id: A0A6J2KX22
names: Similarity
messages: Belongs to the TENT family.

89673:ITK
gene id: 89673:ITK
uniprot id: A0A6J2MUN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:C3
gene id: 89673:C3
uniprot id: A0A6J2MD92
names: Function
names: Subcellular Location Annotation
messages: Acts as a chemoattractant for neutrophils in chronic inflammation.
messages: C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
messages: Secreted

89673:AK8
gene id: 89673:AK8
uniprot id: A0A6J2MV98
uniprot id: A0A7E6DGU3
uniprot id: A0A7E6DGZ8
uniprot id: A0A7E6DH19
uniprot id: A0A7E6DH69
names: Similarity
messages: Belongs to the adenylate kinase family.

89673:LOC114490195
gene id: 89673:LOC114490195
uniprot id: A0A6J2L0V4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TSPAN33
gene id: 89673:TSPAN33
uniprot id: A0A6J2MPJ0
uniprot id: A0A7E6CIM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:SGK1
gene id: 89673:SGK1
uniprot id: A0A6J2LAX9
uniprot id: A0A6J2LCR7
uniprot id: A0A6J2LFP3
uniprot id: A0A7E6DPA2
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

89673:LOC114512966
gene id: 89673:LOC114512966
uniprot id: A0A6J2NCG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

89673:NCBP2
gene id: 89673:NCBP2
uniprot id: A0A6J2L0U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

89673:EPHB4
gene id: 89673:EPHB4
uniprot id: A0A6J2L9V7
uniprot id: A0A7E6DBB4
names: Subcellular Location Annotation
messages: Membrane

89673:SLC25A34
gene id: 89673:SLC25A34
uniprot id: A0A6J2LR14
uniprot id: A0A7E6DPZ9
uniprot id: A0A7E6DQP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:MCHR1
gene id: 89673:MCHR1
uniprot id: A0A6J2NER9
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

89673:LOC114504528
gene id: 89673:LOC114504528
uniprot id: A0A6J2MJ30
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:LOC114504428
gene id: 89673:LOC114504428
uniprot id: A0A7E6DET9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

89673:ABI1
gene id: 89673:ABI1
uniprot id: A0A6J2L6L7
uniprot id: A0A6J2L6M6
uniprot id: A0A6J2L7C2
uniprot id: A0A6J2L7C6
uniprot id: A0A6J2L7D1
uniprot id: A0A6J2L8M1
uniprot id: A0A6J2L8M6
uniprot id: A0A6J2LBE9
uniprot id: A0A6J2LCN6
uniprot id: A0A7E6DIJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

89673:IGFBP1
gene id: 89673:IGFBP1
uniprot id: A0A7E6CJ45
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:HEPHL1
gene id: 89673:HEPHL1
uniprot id: A0A6J2LYD3
names: Similarity
messages: Belongs to the multicopper oxidase family.

89673:ZSCAN10
gene id: 89673:ZSCAN10
uniprot id: A0A7E6D9D4
uniprot id: A0A7E6DA22
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114498894
gene id: 89673:LOC114498894
uniprot id: A0A6J2LSH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:GMPR
gene id: 89673:GMPR
uniprot id: A0A6J2LPR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

89673:LOC114501882
gene id: 89673:LOC114501882
uniprot id: A0A6J2M849
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

89673:LYPD6
gene id: 89673:LYPD6
uniprot id: A0A6J2LGJ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:C6H11orf49
gene id: 89673:C6H11orf49
uniprot id: A0A6J2LUU9
uniprot id: A0A6J2LYQ9
uniprot id: A0A6J2LZC1
uniprot id: A0A7E6E1J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: centriolar satellite

89673:LOC114504923
gene id: 89673:LOC114504923
uniprot id: A0A7E6D1C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

89673:LOC114490364
gene id: 89673:LOC114490364
uniprot id: A0A7E6D246
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

89673:LOC114499263
gene id: 89673:LOC114499263
uniprot id: A0A6J2LUR8
uniprot id: A0A7E6E0B9
uniprot id: A0A7E6E0J1
uniprot id: A0A7E6E0J6
uniprot id: A0A7E6E0K3
uniprot id: A0A7E6E0V3
uniprot id: A0A7E6E0V7
uniprot id: A0A7E6E1I9
uniprot id: A0A7E6E1K9
uniprot id: A0A7E6E1L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

89673:LYPLAL1
gene id: 89673:LYPLAL1
uniprot id: A0A6J2N3U6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

89673:SDHA
gene id: 89673:SDHA
uniprot id: A0A6J2LMF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

89673:MST1
gene id: 89673:MST1
uniprot id: A0A6J2M365
uniprot id: A0A7E6E3T8
names: Caution
names: Similarity
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CRY1
gene id: 89673:CRY1
uniprot id: A0A6J2N984
uniprot id: A0A6J2NEH3
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

89673:SNTA1
gene id: 89673:SNTA1
uniprot id: A0A6J2MKJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

89673:LOC114499024
gene id: 89673:LOC114499024
uniprot id: A0A6J2LTX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:KMT5A
gene id: 89673:KMT5A
uniprot id: A0A6J2MTS7
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

89673:B3GNT8
gene id: 89673:B3GNT8
uniprot id: A0A6J2N6H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:C14H1orf74
gene id: 89673:C14H1orf74
uniprot id: A0A6J2N944
names: Similarity
messages: Belongs to the UPF0739 family.

89673:SLC25A21
gene id: 89673:SLC25A21
uniprot id: A0A6J2L504
uniprot id: A0A7E6E0T2
uniprot id: A0A7E6E0U0
uniprot id: A0A7E6E1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:KDM4C
gene id: 89673:KDM4C
uniprot id: A0A6J2L6N5
uniprot id: A0A7E6DES6
uniprot id: A0A7E6DEW0
uniprot id: A0A7E6DEW6
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

89673:MYH15
gene id: 89673:MYH15
uniprot id: A0A6J2KRV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

89673:LOC114509753
gene id: 89673:LOC114509753
uniprot id: A0A6J2MV65
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

89673:LOC118499536
gene id: 89673:LOC118499536
uniprot id: A0A7E6DBL2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

89673:DNMT1
gene id: 89673:DNMT1
uniprot id: A0A6J2MHP5
uniprot id: A0A7E6E980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

89673:LOC114489882
gene id: 89673:LOC114489882
uniprot id: A0A7E6D1L2
uniprot id: A0A7E6D1M8
uniprot id: A0A7E6D1Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

89673:DNA2
gene id: 89673:DNA2
uniprot id: A0A6J2LTP9
uniprot id: A0A7E6DVI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Mitochondrion
messages: Nucleus

89673:RUVBL2
gene id: 89673:RUVBL2
uniprot id: A0A6J2N5R2
uniprot id: A0A7E6CN87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

89673:LOC114500422
gene id: 89673:LOC114500422
uniprot id: A0A7E6E513
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:VAMP8
gene id: 89673:VAMP8
uniprot id: A0A6J2LY07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

89673:DYNC1LI1
gene id: 89673:DYNC1LI1
uniprot id: A0A6J2M1P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

89673:LOC114507880
gene id: 89673:LOC114507880
uniprot id: A0A6J2MNG6
uniprot id: A0A6J2MUV0
uniprot id: A0A7E6DA65
uniprot id: A0A7E6DAI9
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

89673:LOC114496430
gene id: 89673:LOC114496430
uniprot id: A0A7E6DVC9
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

89673:TMEM258
gene id: 89673:TMEM258
uniprot id: A0A6J2M1H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

89673:KLHDC3
gene id: 89673:KLHDC3
uniprot id: A0A6J2LB53
uniprot id: A0A6J2LF53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

89673:CSF3R
gene id: 89673:CSF3R
uniprot id: A0A6J2LSJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

89673:CHST1
gene id: 89673:CHST1
uniprot id: A0A6J2LZ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

89673:EIF3H
gene id: 89673:EIF3H
uniprot id: A0A6J2NDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with RNF139; the interaction leads to protein translation inhibitions in a ubiquitination-dependent manner.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

89673:NCOA1
gene id: 89673:NCOA1
uniprot id: A0A6J2LR57
uniprot id: A0A6J2LT82
uniprot id: A0A6J2LWL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

89673:FOXG1
gene id: 89673:FOXG1
uniprot id: A0A6J2L967
names: Subcellular Location Annotation
messages: Nucleus

89673:MLNR
gene id: 89673:MLNR
uniprot id: A0A6J2MWB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:LOC114497606
gene id: 89673:LOC114497606
uniprot id: A0A6J2LTN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
messages: Nucleus
messages: spindle pole

89673:TSPAN15
gene id: 89673:TSPAN15
uniprot id: A0A6J2LNS9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:CXCR3
gene id: 89673:CXCR3
uniprot id: A0A7E6CZK1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homomer. Forms heteromers with ACKR4.
messages: Membrane

89673:GOLT1A
gene id: 89673:GOLT1A
uniprot id: A0A7E6CVW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

89673:SSTR2
gene id: 89673:SSTR2
uniprot id: A0A6J2M7L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

89673:WNT9B
gene id: 89673:WNT9B
uniprot id: A0A6J2MGS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:LOC114508281
gene id: 89673:LOC114508281
uniprot id: A0A7E6DE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum

89673:STIM1
gene id: 89673:STIM1
uniprot id: A0A6J2LX23
uniprot id: A0A6J2LY00
uniprot id: A0A6J2M0Y7
uniprot id: A0A6J2M1E9
uniprot id: A0A7E6E009
uniprot id: A0A7E6E021
uniprot id: A0A7E6E153
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:AMT
gene id: 89673:AMT
uniprot id: A0A6J2M945
uniprot id: A0A7E6E4C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

89673:SLC16A13
gene id: 89673:SLC16A13
uniprot id: A0A6J2NJE5
uniprot id: A0A7E6ECF3
uniprot id: A0A7E6EDK1
names: Subcellular Location Annotation
messages: Membrane

89673:VPS72
gene id: 89673:VPS72
uniprot id: A0A6J2KZB5
names: Function
names: Similarity
messages: Belongs to the VPS72/YL1 family.
messages: Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

89673:IL13
gene id: 89673:IL13
uniprot id: A0A7E6CTV7
names: Subunit
messages: Interacts with IL13RA2.

89673:GSG1L2
gene id: 89673:GSG1L2
uniprot id: A0A7E6ECS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

89673:LOC114503313
gene id: 89673:LOC114503313
uniprot id: A0A7E6E9D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

89673:WNT4
gene id: 89673:WNT4
uniprot id: A0A6J2LLU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:MCEE
gene id: 89673:MCEE
uniprot id: A0A6J2KS40
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

89673:FRG1
gene id: 89673:FRG1
uniprot id: A0A6J2MQI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

89673:FABP7
gene id: 89673:FABP7
uniprot id: A0A6J2LDX8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

89673:DIS3
gene id: 89673:DIS3
uniprot id: A0A6J2MRV1
names: Similarity
messages: Belongs to the RNR ribonuclease family.

89673:RPS20
gene id: 89673:RPS20
uniprot id: A0A6J2NAU7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

89673:PTPN1
gene id: 89673:PTPN1
uniprot id: A0A6J2MMJ8
uniprot id: A0A7E6CFX0
uniprot id: A0A7E6CGD3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

89673:LOC114494943
gene id: 89673:LOC114494943
uniprot id: A0A6J2LJL2
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114502520
gene id: 89673:LOC114502520
uniprot id: A0A6J2MB07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

89673:PRKACA
gene id: 89673:PRKACA
uniprot id: A0A6J2MAQ1
uniprot id: A0A7E6E9E5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

89673:SPI1
gene id: 89673:SPI1
uniprot id: A0A6J2LVX2
uniprot id: A0A6J2M1E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:KCNG4
gene id: 89673:KCNG4
uniprot id: A0A6J2KUQ7
uniprot id: A0A7E6CML4
names: Subcellular Location Annotation
messages: Membrane

89673:ZC3H15
gene id: 89673:ZC3H15
uniprot id: A0A6J2LH14
names: Similarity
messages: Belongs to the ZC3H15/TMA46 family.

89673:EAF1
gene id: 89673:EAF1
uniprot id: A0A6J2M415
names: Similarity
messages: Belongs to the EAF family.

89673:SLC35D2
gene id: 89673:SLC35D2
uniprot id: A0A6J2N609
uniprot id: A0A7E6DEB1
uniprot id: A0A7E6DEE2
uniprot id: A0A7E6DEF2
uniprot id: A0A7E6DEF4
names: Subcellular Location Annotation
messages: Membrane

89673:TSSC4
gene id: 89673:TSSC4
uniprot id: A0A6J2LZI7
names: Similarity
messages: Belongs to the TSSC4 family.

89673:NRP1
gene id: 89673:NRP1
uniprot id: A0A6J2L0T3
uniprot id: A0A6J2L1G8
uniprot id: A0A7E6DVY3
uniprot id: A0A7E6DW53
uniprot id: A0A7E6DWX0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:PPP1R1B
gene id: 89673:PPP1R1B
uniprot id: A0A6J2MEQ2
uniprot id: A0A6J2MHT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein phosphatase inhibitor 1 family.
messages: Cytoplasm
messages: Inhibitor of protein-phosphatase 1.

89673:PITPNM1
gene id: 89673:PITPNM1
uniprot id: A0A6J2LVG5
uniprot id: A0A7E6E321
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

89673:LSM8
gene id: 89673:LSM8
uniprot id: A0A6J2MPH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

89673:TSR2
gene id: 89673:TSR2
uniprot id: A0A6J2MFT0
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

89673:LOC114490328
gene id: 89673:LOC114490328
uniprot id: A0A6J2L387
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TENM1
gene id: 89673:TENM1
uniprot id: A0A6J2MD83
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:ADAM22
gene id: 89673:ADAM22
uniprot id: A0A6J2MN25
uniprot id: A0A6J2MN31
uniprot id: A0A6J2MQ07
uniprot id: A0A6J2MQ10
uniprot id: A0A6J2MUC9
uniprot id: A0A6J2MUD5
uniprot id: A0A6J2MUN1
uniprot id: A0A7E6CHU5
uniprot id: A0A7E6CHY4
uniprot id: A0A7E6CI88
uniprot id: A0A7E6CJX0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:DICER1
gene id: 89673:DICER1
uniprot id: A0A6J2L7V7
uniprot id: A0A7E6CRR0
uniprot id: A0A7E6CRS6
names: Function
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.
messages: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

89673:LOC114493117
gene id: 89673:LOC114493117
uniprot id: A0A6J2LDC9
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114500491
gene id: 89673:LOC114500491
uniprot id: A0A7E6E0K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RARA
gene id: 89673:RARA
uniprot id: A0A6J2M8E9
uniprot id: A0A6J2M8Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

89673:DDX17
gene id: 89673:DDX17
uniprot id: A0A6J2N892
uniprot id: A0A6J2NDG4
names: Similarity
messages: Belongs to the DEAD box helicase family.

89673:POLR2H
gene id: 89673:POLR2H
uniprot id: A0A6J2KYK5
uniprot id: A0A6J2L098
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

89673:DDRGK1
gene id: 89673:DDRGK1
uniprot id: A0A6J2MHD3
names: Similarity
messages: Belongs to the DDRGK1 family.

89673:LOC114500217
gene id: 89673:LOC114500217
uniprot id: A0A6J2M3M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114509108
gene id: 89673:LOC114509108
uniprot id: A0A6J2MTW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

89673:IL26
gene id: 89673:IL26
uniprot id: A0A6J2NBP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

89673:EEF1B2
gene id: 89673:EEF1B2
uniprot id: A0A7E6DIR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

89673:GRK6
gene id: 89673:GRK6
uniprot id: A0A6J2N0F8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

89673:NCOA2
gene id: 89673:NCOA2
uniprot id: A0A6J2NH76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

89673:GOT2
gene id: 89673:GOT2
uniprot id: A0A6J2KT27
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

89673:SMUG1
gene id: 89673:SMUG1
uniprot id: A0A6J2NA70
uniprot id: A0A7E6D6D5
uniprot id: A0A7E6D956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. SMUG1 family.
messages: Nucleus

89673:PSMB3
gene id: 89673:PSMB3
uniprot id: A0A6J2MBZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

89673:FERMT2
gene id: 89673:FERMT2
uniprot id: A0A6J2L3P5
uniprot id: A0A6J2L6Y5
uniprot id: A0A7E6CG97
uniprot id: A0A7E6CGC9
uniprot id: A0A7E6CGD9
uniprot id: A0A7E6CGL5
names: Similarity
messages: Belongs to the kindlin family.

89673:MYO1A
gene id: 89673:MYO1A
uniprot id: A0A6J2NCG9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:LOC114507719
gene id: 89673:LOC114507719
uniprot id: A0A6J2MPQ7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a regulator of keratinocyte proliferation or differentiation.
messages: Nucleus

89673:LOC114512248
gene id: 89673:LOC114512248
uniprot id: A0A6J2N4Y0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

89673:CEP19
gene id: 89673:CEP19
uniprot id: A0A6J2KY70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

89673:MET
gene id: 89673:MET
uniprot id: A0A6J2MTI3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TMC5
gene id: 89673:TMC5
uniprot id: A0A6J2M6K2
uniprot id: A0A7E6DBS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

89673:HSD17B10
gene id: 89673:HSD17B10
uniprot id: A0A6J2MHE5
uniprot id: A0A7E6CZI3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:LOC114489471
gene id: 89673:LOC114489471
uniprot id: A0A7E6CYC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:POU6F2
gene id: 89673:POU6F2
uniprot id: A0A6J2MUG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

89673:GJB2
gene id: 89673:GJB2
uniprot id: A0A7E6D5I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:CDK9
gene id: 89673:CDK9
uniprot id: A0A6J2MFI0
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:GDA
gene id: 89673:GDA
uniprot id: A0A6J2LXK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

89673:TBXT
gene id: 89673:TBXT
uniprot id: A0A6J2L0J2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:CDV3
gene id: 89673:CDV3
uniprot id: A0A6J2M2V5
uniprot id: A0A7E6E4P0
uniprot id: A0A7E6E5E7
uniprot id: A0A7E6E699
uniprot id: A0A7E6E6E1
names: Similarity
messages: Belongs to the CDV3 family.

89673:ACAP3
gene id: 89673:ACAP3
uniprot id: A0A6J2LNI0
uniprot id: A0A7E6DPE2
uniprot id: A0A7E6DPY5
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

89673:ACOX3
gene id: 89673:ACOX3
uniprot id: A0A6J2KZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

89673:RPF2
gene id: 89673:RPF2
uniprot id: A0A6J2LC64
uniprot id: A0A7E6DMV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

89673:SPOCK3
gene id: 89673:SPOCK3
uniprot id: A0A6J2MA98
uniprot id: A0A6J2MFC7
uniprot id: A0A6J2MFT2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114508079
gene id: 89673:LOC114508079
uniprot id: A0A6J2MVJ9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:LOC114513138
gene id: 89673:LOC114513138
uniprot id: A0A6J2N6E4
uniprot id: A0A6J2ND06
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

89673:DLGAP3
gene id: 89673:DLGAP3
uniprot id: A0A6J2LLX0
names: Similarity
messages: Belongs to the SAPAP family.

89673:PFKFB3
gene id: 89673:PFKFB3
uniprot id: A0A6J2L3E5
uniprot id: A0A6J2L426
uniprot id: A0A6J2L5R0
uniprot id: A0A6J2L5R3
uniprot id: A0A6J2L800
uniprot id: A0A7E6DMG2
uniprot id: A0A7E6DMG4
uniprot id: A0A7E6DMX6
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

89673:SEC16A
gene id: 89673:SEC16A
uniprot id: A0A6J2MEF1
uniprot id: A0A7E6DH43
uniprot id: A0A7E6DH91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

89673:NKX2-2
gene id: 89673:NKX2-2
uniprot id: A0A6J2MMN6
names: Subcellular Location Annotation
messages: Nucleus

89673:ATXN7L3
gene id: 89673:ATXN7L3
uniprot id: A0A6J2MA81
uniprot id: A0A7E6EE61
uniprot id: A0A7E6EEY9
uniprot id: A0A7E6EFX4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of some SAGA transcription coactivator-HAT complexes, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ENY2, ATXN7, ATXN7L3, and USP22 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with ENY2 and USP22.
messages: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B.
messages: Nucleus
messages: The C-terminal SGF11-type zinc-finger domain together with the C-terminal catalytic domain of USP22 forms the 'catalytic lobe' of the SAGA deubiquitination module.
messages: The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.

89673:IGF2BP2
gene id: 89673:IGF2BP2
uniprot id: A0A6J2KZ00
uniprot id: A0A6J2KZL7
uniprot id: A0A7E6D335
uniprot id: A0A7E6D369
uniprot id: A0A7E6D3A4
uniprot id: A0A7E6D3U3
uniprot id: A0A7E6D5Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: P-body
messages: Stress granule

89673:CASR
gene id: 89673:CASR
uniprot id: A0A6J2L5T7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:AGPAT3
gene id: 89673:AGPAT3
uniprot id: A0A6J2L0G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane

89673:LOC114499151
gene id: 89673:LOC114499151
uniprot id: A0A6J2LY65
names: Similarity
messages: Belongs to the NXPE family.

89673:SMAD2
gene id: 89673:SMAD2
uniprot id: A0A7E6CIU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

89673:LSM7
gene id: 89673:LSM7
uniprot id: A0A6J2M9B4
uniprot id: A0A7E6EAU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

89673:LAPTM5
gene id: 89673:LAPTM5
uniprot id: A0A6J2LRD9
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

89673:PPP1R35
gene id: 89673:PPP1R35
uniprot id: A0A6J2MLU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP1R35 family.
messages: centriole

89673:CARTPT
gene id: 89673:CARTPT
uniprot id: A0A6J2N6P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

89673:FLT3
gene id: 89673:FLT3
uniprot id: A0A7E6D4N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

89673:PRAF2
gene id: 89673:PRAF2
uniprot id: A0A6J2MKA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

89673:OTUD7B
gene id: 89673:OTUD7B
uniprot id: A0A7E6CVJ3
uniprot id: A0A7E6CVJ9
uniprot id: A0A7E6CWB0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:FUT8
gene id: 89673:FUT8
uniprot id: A0A6J2L4S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

89673:L1CAM
gene id: 89673:L1CAM
uniprot id: A0A6J2MHB0
uniprot id: A0A7E6CYR0
uniprot id: A0A7E6CYV1
uniprot id: A0A7E6CYV6
uniprot id: A0A7E6CZ74
uniprot id: A0A7E6D1F0
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

89673:LOC114503675
gene id: 89673:LOC114503675
uniprot id: A0A6J2MFR2
uniprot id: A0A7E6EAZ3
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:PRDM15
gene id: 89673:PRDM15
uniprot id: A0A7E6DBU4
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114493109
gene id: 89673:LOC114493109
uniprot id: A0A7E6DQJ8
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:FOXJ3
gene id: 89673:FOXJ3
uniprot id: A0A6J2LMP0
uniprot id: A0A6J2LNF2
names: Subcellular Location Annotation
messages: Nucleus

89673:CRYBG3
gene id: 89673:CRYBG3
uniprot id: A0A6J2L1J7
uniprot id: A0A7E6D496
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

89673:LOC114489126
gene id: 89673:LOC114489126
uniprot id: A0A7E6D0G9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:AK1
gene id: 89673:AK1
uniprot id: A0A6J2LTW8
uniprot id: A0A6J2LYX8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

89673:LOC114507478
gene id: 89673:LOC114507478
uniprot id: A0A6J2MNL8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:ODF1
gene id: 89673:ODF1
uniprot id: A0A6J2NIZ5
names: Function
messages: Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.

89673:LOC114500828
gene id: 89673:LOC114500828
uniprot id: A0A7E6E1E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CFAP91
gene id: 89673:CFAP91
uniprot id: A0A6J2L0T6
uniprot id: A0A7E6D497
names: Similarity
messages: Belongs to the CFAP91 family.

89673:CXCR2
gene id: 89673:CXCR2
uniprot id: A0A6J2LDB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:NTMT1
gene id: 89673:NTMT1
uniprot id: A0A6J2M4Y6
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

89673:GJA4
gene id: 89673:GJA4
uniprot id: A0A6J2LQ99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:PDE8A
gene id: 89673:PDE8A
uniprot id: A0A6J2KRM0
uniprot id: A0A7E6CMW2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:ATXN2L
gene id: 89673:ATXN2L
uniprot id: A0A6J2LJ86
uniprot id: A0A6J2LK78
uniprot id: A0A6J2LKC5
uniprot id: A0A6J2LKE1
uniprot id: A0A6J2LKF2
uniprot id: A0A6J2LLB0
uniprot id: A0A6J2LLF8
uniprot id: A0A6J2LP07
uniprot id: A0A6J2LP17
uniprot id: A0A6J2LP27
uniprot id: A0A6J2LPL4
uniprot id: A0A7E6DCJ1
uniprot id: A0A7E6DCJ5
uniprot id: A0A7E6DCR1
uniprot id: A0A7E6DD01
uniprot id: A0A7E6DDA8
uniprot id: A0A7E6DDQ4
uniprot id: A0A7E6DDQ5
names: Similarity
messages: Belongs to the ataxin-2 family.

89673:CDCA8
gene id: 89673:CDCA8
uniprot id: A0A6J2LIW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

89673:CCDC149
gene id: 89673:CCDC149
uniprot id: A0A6J2L9Q5
uniprot id: A0A6J2LDP9
names: Similarity
messages: Belongs to the CCDC149 family.

89673:AURKA
gene id: 89673:AURKA
uniprot id: A0A6J2MLN8
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

89673:ISOC1
gene id: 89673:ISOC1
uniprot id: A0A6J2MN77
names: Similarity
messages: Belongs to the isochorismatase family.

89673:LOC114514181
gene id: 89673:LOC114514181
uniprot id: A0A6J2NBG2
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Monomer.

89673:GPHB5
gene id: 89673:GPHB5
uniprot id: A0A6J2L353
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

89673:LOC114504937
gene id: 89673:LOC114504937
uniprot id: A0A6J2MKT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

89673:KLC2
gene id: 89673:KLC2
uniprot id: A0A6J2M4M1
uniprot id: A0A7E6E3J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

89673:GTF2H1
gene id: 89673:GTF2H1
uniprot id: A0A7E6E1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

89673:ICAM2
gene id: 89673:ICAM2
uniprot id: A0A7E6EEA7
uniprot id: A0A7E6EEJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

89673:RPL7
gene id: 89673:RPL7
uniprot id: A0A6J2M339
uniprot id: A0A6J2M4L3
uniprot id: A0A7E6E6J2
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

89673:PRPF18
gene id: 89673:PRPF18
uniprot id: A0A6J2L4T0
uniprot id: A0A6J2L6Y3
uniprot id: A0A7E6DN45
uniprot id: A0A7E6DN50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

89673:NLRP8
gene id: 89673:NLRP8
uniprot id: A0A6J2N4D4
names: Similarity
messages: Belongs to the NLRP family.

89673:HOGA1
gene id: 89673:HOGA1
uniprot id: A0A6J2LHU8
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Homotetramer.

89673:NINJ1
gene id: 89673:NINJ1
uniprot id: A0A6J2KW42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

89673:RPIA
gene id: 89673:RPIA
uniprot id: A0A6J2LUW9
uniprot id: A0A7E6DTK7
uniprot id: A0A7E6DUF3
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

89673:LCA5
gene id: 89673:LCA5
uniprot id: A0A6J2LGE4
names: Similarity
messages: Belongs to the LCA5 family.

89673:SLC33A1
gene id: 89673:SLC33A1
uniprot id: A0A6J2KY65
uniprot id: A0A7E6D5D7
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114492291
gene id: 89673:LOC114492291
uniprot id: A0A6J2L9L8
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

89673:DONSON
gene id: 89673:DONSON
uniprot id: A0A6J2L2D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DONSON family.
messages: Nucleus

89673:OPRL1
gene id: 89673:OPRL1
uniprot id: A0A6J2MJX3
uniprot id: A0A6J2MR19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

89673:LOC114498540
gene id: 89673:LOC114498540
uniprot id: A0A6J2LRC7
names: Subcellular Location Annotation
messages: Membrane

89673:CRYBB3
gene id: 89673:CRYBB3
uniprot id: A0A6J2MY76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

89673:NAA10
gene id: 89673:NAA10
uniprot id: A0A6J2MGB9
uniprot id: A0A6J2MGL3
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

89673:ZDHHC16
gene id: 89673:ZDHHC16
uniprot id: A0A6J2LLW0
uniprot id: A0A7E6DVF5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:UPF3A
gene id: 89673:UPF3A
uniprot id: A0A6J2MT09
uniprot id: A0A6J2MT16
uniprot id: A0A7E6CKH0
uniprot id: A0A7E6CKH3
uniprot id: A0A7E6CMJ5
names: Similarity
messages: Belongs to the RENT3 family.

89673:TM9SF4
gene id: 89673:TM9SF4
uniprot id: A0A6J2MPE4
uniprot id: A0A7E6CF76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

89673:UCKL1
gene id: 89673:UCKL1
uniprot id: A0A6J2MMM1
uniprot id: A0A6J2MRU2
uniprot id: A0A7E6CG35
uniprot id: A0A7E6CG39
uniprot id: A0A7E6CGE1
uniprot id: A0A7E6CGL2
uniprot id: A0A7E6CGL8
uniprot id: A0A7E6CI84
names: Similarity
messages: Belongs to the uridine kinase family.

89673:ADCY9
gene id: 89673:ADCY9
uniprot id: A0A6J2MN24
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

89673:LOC114499836
gene id: 89673:LOC114499836
uniprot id: A0A6J2M245
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SCNM1
gene id: 89673:SCNM1
uniprot id: A0A6J2KSY8
uniprot id: A0A6J2KWS5
uniprot id: A0A7E6CXF1
names: Function
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.
messages: nucleoplasm

89673:LOC114514573
gene id: 89673:LOC114514573
uniprot id: A0A6J2NCP4
uniprot id: A0A7E6E8C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Membrane
messages: Mitochondrion inner membrane

89673:LOC114492639
gene id: 89673:LOC114492639
uniprot id: A0A6J2L5Z0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:SMAD6
gene id: 89673:SMAD6
uniprot id: A0A6J2L736
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

89673:KPNA6
gene id: 89673:KPNA6
uniprot id: A0A6J2LMK8
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

89673:SF3A2
gene id: 89673:SF3A2
uniprot id: A0A6J2MEU8
names: Similarity
messages: Belongs to the SF3A2 family.

89673:XYLT1
gene id: 89673:XYLT1
uniprot id: A0A6J2MWN2
uniprot id: A0A7E6DDJ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

89673:RNF34
gene id: 89673:RNF34
uniprot id: A0A6J2MU18
uniprot id: A0A6J2N092
names: Subcellular Location Annotation
messages: Cell membrane

89673:PEX5
gene id: 89673:PEX5
uniprot id: A0A6J2N6T3
uniprot id: A0A6J2N705
uniprot id: A0A6J2NBK9
uniprot id: A0A6J2NCA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
messages: Cytoplasm
messages: Membrane

89673:SRP54
gene id: 89673:SRP54
uniprot id: A0A6J2LB11
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Nucleus speckle

89673:E2F6
gene id: 89673:E2F6
uniprot id: A0A6J2LYK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

89673:LOC114504322
gene id: 89673:LOC114504322
uniprot id: A0A7E6EEG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:PEA15
gene id: 89673:PEA15
uniprot id: A0A6J2N3J1
names: Subcellular Location Annotation
messages: Cytoplasm

89673:HDAC2
gene id: 89673:HDAC2
uniprot id: A0A6J2LG40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

89673:SKOR2
gene id: 89673:SKOR2
uniprot id: A0A6J2MMH2
names: Similarity
messages: Belongs to the SKI family.

89673:LOC114491969
gene id: 89673:LOC114491969
uniprot id: A0A7E6DRZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

89673:LOC118501112
gene id: 89673:LOC118501112
uniprot id: A0A7E6DXJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:LOC114503535
gene id: 89673:LOC114503535
uniprot id: A0A7E6EC98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SZRD1
gene id: 89673:SZRD1
uniprot id: A0A6J2LKG1
uniprot id: A0A6J2LP71
names: Similarity
messages: Belongs to the SZRD1 family.

89673:STXBP5L
gene id: 89673:STXBP5L
uniprot id: A0A6J2KZJ7
uniprot id: A0A6J2L1S8
uniprot id: A0A6J2L3Q5
uniprot id: A0A7E6D428
uniprot id: A0A7E6D484
uniprot id: A0A7E6D4A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

89673:TSR3
gene id: 89673:TSR3
uniprot id: A0A6J2MKA4
uniprot id: A0A7E6DC66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CFL2
gene id: 89673:CFL2
uniprot id: A0A6J2L4H5
uniprot id: A0A6J2L7X7
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

89673:QKI
gene id: 89673:QKI
uniprot id: A0A7E6DNW3
uniprot id: A0A7E6DPE5
uniprot id: A0A7E6DPJ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer. Does not require RNA to homodimerize. Able to heterodimerize with BICC1.
messages: Nucleus
messages: RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor.

89673:REEP2
gene id: 89673:REEP2
uniprot id: A0A6J2MVN9
uniprot id: A0A6J2N0A9
uniprot id: A0A6J2N0V4
uniprot id: A0A7E6CSM2
uniprot id: A0A7E6CT25
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:POLR2J
gene id: 89673:POLR2J
uniprot id: A0A6J2MBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

89673:LOC114504967
gene id: 89673:LOC114504967
uniprot id: A0A6J2MKB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

89673:SH3KBP1
gene id: 89673:SH3KBP1
uniprot id: A0A6J2MJG1
uniprot id: A0A7E6CZK7
uniprot id: A0A7E6CZL4
uniprot id: A0A7E6CZW3
uniprot id: A0A7E6D0H4
uniprot id: A0A7E6D0H9
names: Subcellular Location Annotation
messages: focal adhesion

89673:LOC114493871
gene id: 89673:LOC114493871
uniprot id: A0A6J2LA93
names: Similarity
messages: Belongs to the MHC class I family.

89673:LOC114505391
gene id: 89673:LOC114505391
uniprot id: A0A7E6D0P0
names: Similarity
messages: Belongs to the SUI1 family.

89673:NIFK
gene id: 89673:NIFK
uniprot id: A0A7E6DK38
uniprot id: A0A7E6DKD9
uniprot id: A0A7E6DKM3
names: Subcellular Location Annotation
messages: nucleolus

89673:NSUN6
gene id: 89673:NSUN6
uniprot id: A0A6J2L9G5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

89673:LSM2
gene id: 89673:LSM2
uniprot id: A0A6J2LIK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

89673:PLXNB1
gene id: 89673:PLXNB1
uniprot id: A0A6J2M839
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:MMACHC
gene id: 89673:MMACHC
uniprot id: A0A6J2LQX0
uniprot id: A0A7E6DSV6
names: Similarity
messages: Belongs to the MMACHC family.

89673:OLFM2
gene id: 89673:OLFM2
uniprot id: A0A6J2MBN0
uniprot id: A0A6J2MHP4
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

89673:KDM4A
gene id: 89673:KDM4A
uniprot id: A0A6J2LJ61
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

89673:ACSL1
gene id: 89673:ACSL1
uniprot id: A0A6J2MRW5
uniprot id: A0A6J2MRX3
uniprot id: A0A7E6CL62
uniprot id: A0A7E6CL75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

89673:SLC4A2
gene id: 89673:SLC4A2
uniprot id: A0A6J2MP07
uniprot id: A0A6J2MTL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane
messages: Plasma membrane anion exchange protein of wide distribution.

89673:LOC114512883
gene id: 89673:LOC114512883
uniprot id: A0A6J2NC73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

89673:PCLAF
gene id: 89673:PCLAF
uniprot id: A0A6J2L3K8
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

89673:DEF8
gene id: 89673:DEF8
uniprot id: A0A6J2L2N3
uniprot id: A0A7E6CQE1
names: Similarity
messages: Belongs to the DEF8 family.

89673:NRXN3
gene id: 89673:NRXN3
uniprot id: A0A7E6D964
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:NLGN2
gene id: 89673:NLGN2
uniprot id: A0A6J2NJ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

89673:RDH5
gene id: 89673:RDH5
uniprot id: A0A7E6D6A2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:NKX2-3
gene id: 89673:NKX2-3
uniprot id: A0A6J2LJQ5
names: Subcellular Location Annotation
messages: Nucleus

89673:YWHAE
gene id: 89673:YWHAE
uniprot id: A0A6J2M6K8
uniprot id: A0A6J2MA28
uniprot id: A0A7E6ECR5
names: Similarity
messages: Belongs to the 14-3-3 family.

89673:MGST1
gene id: 89673:MGST1
uniprot id: A0A6J2N961
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

89673:LOC114490190
gene id: 89673:LOC114490190
uniprot id: A0A6J2L0U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DYNLL1
gene id: 89673:DYNLL1
uniprot id: A0A6J2MU72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

89673:CCHCR1
gene id: 89673:CCHCR1
uniprot id: A0A6J2LGE5
uniprot id: A0A7E6DKN6
uniprot id: A0A7E6DKP8
uniprot id: A0A7E6DKQ1
uniprot id: A0A7E6DL32
uniprot id: A0A7E6DLE3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a regulator of keratinocyte proliferation or differentiation.
messages: Nucleus

89673:LOC114490770
gene id: 89673:LOC114490770
uniprot id: A0A7E6D2R0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:CLDN5
gene id: 89673:CLDN5
uniprot id: A0A6J2N1M6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:ERAP1
gene id: 89673:ERAP1
uniprot id: A0A6J2LD47
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

89673:NR2F2
gene id: 89673:NR2F2
uniprot id: A0A6J2KTK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

89673:SMARCD2
gene id: 89673:SMARCD2
uniprot id: A0A6J2MBJ5
names: Similarity
messages: Belongs to the SMARCD family.

89673:CAMKK1
gene id: 89673:CAMKK1
uniprot id: A0A7E6ECU6
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114497717
gene id: 89673:LOC114497717
uniprot id: A0A6J2LU38
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:JAK2
gene id: 89673:JAK2
uniprot id: A0A6J2LMK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

89673:DNHD1
gene id: 89673:DNHD1
uniprot id: A0A7E6E4C1
names: Similarity
messages: Belongs to the dynein heavy chain family.

89673:LOC114498875
gene id: 89673:LOC114498875
uniprot id: A0A7E6E044
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:BROX
gene id: 89673:BROX
uniprot id: A0A6J2N3H0
uniprot id: A0A6J2N9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BROX family.
messages: Membrane

89673:GLIPR1L1
gene id: 89673:GLIPR1L1
uniprot id: A0A6J2N5P5
names: Similarity
messages: Belongs to the CRISP family.

89673:MRPS25
gene id: 89673:MRPS25
uniprot id: A0A6J2M7R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

89673:AREG
gene id: 89673:AREG
uniprot id: A0A6J2L308
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ARSB
gene id: 89673:ARSB
uniprot id: A0A6J2MXM0
uniprot id: A0A7E6DAI7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

89673:LOC114506643
gene id: 89673:LOC114506643
uniprot id: A0A6J2MLG9
names: Similarity
messages: Belongs to the CBP3 family.

89673:LOC114500569
gene id: 89673:LOC114500569
uniprot id: A0A6J2M1F6
uniprot id: A0A7E6E2Y1
names: Similarity
messages: Belongs to the MS4A family.

89673:TRMT5
gene id: 89673:TRMT5
uniprot id: A0A6J2L8A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

89673:ARL3
gene id: 89673:ARL3
uniprot id: A0A6J2LP89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

89673:LOC114500259
gene id: 89673:LOC114500259
uniprot id: A0A6J2M0A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114500674
gene id: 89673:LOC114500674
uniprot id: A0A6J2LZQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC118499902
gene id: 89673:LOC118499902
uniprot id: A0A7E6DHH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KHDC1 family.
messages: Cytoplasm
messages: Nucleus

89673:GDPD5
gene id: 89673:GDPD5
uniprot id: A0A6J2LZX4
uniprot id: A0A6J2M5G9
uniprot id: A0A7E6DZR8
uniprot id: A0A7E6E0T0
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

89673:CBFA2T2
gene id: 89673:CBFA2T2
uniprot id: A0A6J2MLF4
uniprot id: A0A7E6CF65
names: Similarity
messages: Belongs to the CBFA2T family.

89673:LMLN
gene id: 89673:LMLN
uniprot id: A0A6J2L1G7
uniprot id: A0A6J2L4W6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

89673:LOC118500899
gene id: 89673:LOC118500899
uniprot id: A0A7E6DV77
uniprot id: A0A7E6DW66
uniprot id: A0A7E6DW72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

89673:ERCC4
gene id: 89673:ERCC4
uniprot id: A0A7E6DCJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

89673:LSM3
gene id: 89673:LSM3
uniprot id: A0A6J2M7I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

89673:TSPYL1
gene id: 89673:TSPYL1
uniprot id: A0A6J2LH41
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

89673:TMCO4
gene id: 89673:TMCO4
uniprot id: A0A6J2LR07
names: Similarity
messages: Belongs to the TMCO4 family.

89673:NIPAL4
gene id: 89673:NIPAL4
uniprot id: A0A6J2N1S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

89673:TOE1
gene id: 89673:TOE1
uniprot id: A0A6J2LPC5
uniprot id: A0A7E6DSU7
names: Similarity
messages: Belongs to the CAF1 family.

89673:TOP2B
gene id: 89673:TOP2B
uniprot id: A0A6J2M6D9
uniprot id: A0A7E6E577
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

89673:AGPAT1
gene id: 89673:AGPAT1
uniprot id: A0A6J2LBQ7
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

89673:LOC114499096
gene id: 89673:LOC114499096
uniprot id: A0A7E6E236
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114495134
gene id: 89673:LOC114495134
uniprot id: A0A6J2LJX1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:LOC114503290
gene id: 89673:LOC114503290
uniprot id: A0A7E6EFF6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

89673:HBQ1
gene id: 89673:HBQ1
uniprot id: A0A6J2MZM6
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

89673:GASK1A
gene id: 89673:GASK1A
uniprot id: A0A7E6E458
uniprot id: A0A7E6E5M9
names: Similarity
messages: Belongs to the GASK family.

89673:CENPU
gene id: 89673:CENPU
uniprot id: A0A7E6CJ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

89673:RELL2
gene id: 89673:RELL2
uniprot id: A0A6J2MVX5
uniprot id: A0A7E6CTQ0
names: Similarity
messages: Belongs to the RELT family.

89673:DOCK7
gene id: 89673:DOCK7
uniprot id: A0A6J2LM48
uniprot id: A0A6J2LPV8
uniprot id: A0A7E6DSA3
uniprot id: A0A7E6DSG2
uniprot id: A0A7E6DSG8
uniprot id: A0A7E6DSY9
uniprot id: A0A7E6DT37
uniprot id: A0A7E6DTH9
uniprot id: A0A7E6DTI7
names: Similarity
messages: Belongs to the DOCK family.

89673:SLC35F2
gene id: 89673:SLC35F2
uniprot id: A0A6J2M1Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

89673:IL17D
gene id: 89673:IL17D
uniprot id: A0A7E6CZB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

89673:HMOX1
gene id: 89673:HMOX1
uniprot id: A0A6J2NEV7
names: Similarity
messages: Belongs to the heme oxygenase family.

89673:SPOCK1
gene id: 89673:SPOCK1
uniprot id: A0A6J2N298
uniprot id: A0A6J2N314
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:PROK2
gene id: 89673:PROK2
uniprot id: A0A6J2M359
uniprot id: A0A7E6E687
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

89673:RNFT2
gene id: 89673:RNFT2
uniprot id: A0A6J2MVP3
uniprot id: A0A6J2MVR1
uniprot id: A0A7E6CUP7
uniprot id: A0A7E6CWS3
names: Subcellular Location Annotation
messages: Membrane

89673:LOC118498388
gene id: 89673:LOC118498388
uniprot id: A0A7E6CYZ3
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

89673:WNT2
gene id: 89673:WNT2
uniprot id: A0A6J2MW18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:TGFB1
gene id: 89673:TGFB1
uniprot id: A0A6J2N544
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Required to maintain the Transforming growth factor beta-1 (TGF-beta-1) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-1 and regulates its activation via interaction with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS, that control activation of TGF-beta-1. Interaction with LRRC33/NRROS regulates activation of TGF-beta-1 in macrophages and microglia. Interaction with LRRC32/GARP controls activation of TGF-beta-1 on the surface of activated regulatory T-cells (Tregs). Interaction with integrins (ITGAV:ITGB6 or ITGAV:ITGB8) results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-1.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

89673:LOC114503560
gene id: 89673:LOC114503560
uniprot id: A0A6J2MFX0
uniprot id: A0A7E6EFY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

89673:SLC66A3
gene id: 89673:SLC66A3
uniprot id: A0A6J2M005
names: Subcellular Location Annotation
messages: Membrane

89673:MRM2
gene id: 89673:MRM2
uniprot id: A0A6J2MYP6
uniprot id: A0A7E6CU10
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

89673:NOL8
gene id: 89673:NOL8
uniprot id: A0A6J2N8Z2
uniprot id: A0A6J2N9B7
uniprot id: A0A7E6D7Q6
names: Subcellular Location Annotation
messages: nucleolus

89673:DPPA2
gene id: 89673:DPPA2
uniprot id: A0A7E6D424
names: Subcellular Location Annotation
messages: Nucleus

89673:IZUMO4
gene id: 89673:IZUMO4
uniprot id: A0A7E6EH40
names: Similarity
messages: Belongs to the Izumo family.

89673:MGA
gene id: 89673:MGA
uniprot id: A0A6J2L397
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:KCND1
gene id: 89673:KCND1
uniprot id: A0A6J2MGR7
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

89673:LOC114504794
gene id: 89673:LOC114504794
uniprot id: A0A6J2MEH5
uniprot id: A0A7E6CYZ0
uniprot id: A0A7E6CZE0
uniprot id: A0A7E6D1L7
names: Similarity
messages: Belongs to the SNF7 family.

89673:LDAH
gene id: 89673:LDAH
uniprot id: A0A6J2LXN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

89673:PNPT1
gene id: 89673:PNPT1
uniprot id: A0A6J2LVP0
uniprot id: A0A7E6DYB4
names: Similarity
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.

89673:TACC2
gene id: 89673:TACC2
uniprot id: A0A6J2LMQ0
uniprot id: A0A6J2LP14
uniprot id: A0A6J2LT14
uniprot id: A0A7E6DVP7
uniprot id: A0A7E6DWA8
uniprot id: A0A7E6DX51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

89673:PUS1
gene id: 89673:PUS1
uniprot id: A0A6J2KZ99
uniprot id: A0A7E6CS83
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

89673:PMEL
gene id: 89673:PMEL
uniprot id: A0A6J2NDD8
names: Similarity
messages: Belongs to the PMEL/NMB family.

89673:NPM1
gene id: 89673:NPM1
uniprot id: A0A6J2MVT1
uniprot id: A0A7E6CRY0
names: Similarity
messages: Belongs to the nucleoplasmin family.

89673:TSPAN31
gene id: 89673:TSPAN31
uniprot id: A0A6J2N6H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:AIDA
gene id: 89673:AIDA
uniprot id: A0A6J2NAK2
names: Similarity
messages: Belongs to the AIDA family.

89673:ATG9B
gene id: 89673:ATG9B
uniprot id: A0A6J2MNJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

89673:GAMT
gene id: 89673:GAMT
uniprot id: A0A6J2MA79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor.
messages: Monomer.

89673:ANKH
gene id: 89673:ANKH
uniprot id: A0A6J2LMC0
uniprot id: A0A7E6DCX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

89673:ALDH3A2
gene id: 89673:ALDH3A2
uniprot id: A0A6J2NE75
uniprot id: A0A7E6EAZ5
uniprot id: A0A7E6ECJ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

89673:LOC114495519
gene id: 89673:LOC114495519
uniprot id: A0A6J2LLF6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

89673:NDUFC2
gene id: 89673:NDUFC2
uniprot id: A0A6J2M152
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane

89673:TENM4
gene id: 89673:TENM4
uniprot id: A0A6J2LWS3
uniprot id: A0A7E6DZK8
uniprot id: A0A7E6DZL4
uniprot id: A0A7E6E020
uniprot id: A0A7E6E0K4
uniprot id: A0A7E6E0T3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:CPA4
gene id: 89673:CPA4
uniprot id: A0A6J2MQI9
names: Similarity
messages: Belongs to the peptidase M14 family.

89673:LOC114508802
gene id: 89673:LOC114508802
uniprot id: A0A7E6CKW5
names: Similarity
messages: Belongs to the SKP1 family.

89673:PPM1L
gene id: 89673:PPM1L
uniprot id: A0A6J2L0C3
names: Similarity
messages: Belongs to the PP2C family.

89673:EFNB2
gene id: 89673:EFNB2
uniprot id: A0A6J2MRF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114509365
gene id: 89673:LOC114509365
uniprot id: A0A6J2N0E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

89673:PDP1
gene id: 89673:PDP1
uniprot id: A0A6J2NAD2
uniprot id: A0A6J2NC93
names: Similarity
messages: Belongs to the PP2C family.

89673:MICALL1
gene id: 89673:MICALL1
uniprot id: A0A6J2N677
names: Subcellular Location Annotation
messages: Membrane

89673:RIPK2
gene id: 89673:RIPK2
uniprot id: A0A7E6E6T9
uniprot id: A0A7E6E7G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Found in a signaling complex consisting of at least ARHGEF2, NOD2 and RIPK2.
messages: Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.

89673:NEXMIF
gene id: 89673:NEXMIF
uniprot id: A0A6J2MFJ8
names: Subcellular Location Annotation
messages: Nucleus

89673:TNFRSF6B
gene id: 89673:TNFRSF6B
uniprot id: A0A6J2MPU4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CASD1
gene id: 89673:CASD1
uniprot id: A0A6J2MNS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane

89673:LOC118500645
gene id: 89673:LOC118500645
uniprot id: A0A7E6DT75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:FAM216A
gene id: 89673:FAM216A
uniprot id: A0A6J2MVK0
uniprot id: A0A7E6CS25
uniprot id: A0A7E6CSA7
names: Similarity
messages: Belongs to the FAM216 family.

89673:RAB29
gene id: 89673:RAB29
uniprot id: A0A6J2N4H5
uniprot id: A0A6J2N4I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

89673:NT5DC1
gene id: 89673:NT5DC1
uniprot id: A0A6J2LDC1
uniprot id: A0A7E6DMW3
uniprot id: A0A7E6DND5
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

89673:MRPL16
gene id: 89673:MRPL16
uniprot id: A0A6J2M054
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

89673:RPA4
gene id: 89673:RPA4
uniprot id: A0A6J2MJ76
names: Similarity
messages: Belongs to the replication factor A protein 2 family.

89673:LOC114512415
gene id: 89673:LOC114512415
uniprot id: A0A6J2N3V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

89673:BCL9
gene id: 89673:BCL9
uniprot id: A0A6J2KT59
uniprot id: A0A6J2KWZ3
uniprot id: A0A6J2KZ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

89673:LOC114497078
gene id: 89673:LOC114497078
uniprot id: A0A7E6DVD0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

89673:KRT1
gene id: 89673:KRT1
uniprot id: A0A6J2N6D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

89673:SLC28A1
gene id: 89673:SLC28A1
uniprot id: A0A7E6CMY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

89673:LOC114497556
gene id: 89673:LOC114497556
uniprot id: A0A6J2LN10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Cell membrane
messages: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.
messages: Membrane
messages: Nucleus outer membrane

89673:ADAM33
gene id: 89673:ADAM33
uniprot id: A0A7E6CEY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114513026
gene id: 89673:LOC114513026
uniprot id: A0A6J2N5Z5
names: Similarity
messages: Belongs to the intermediate filament family.

89673:GCG
gene id: 89673:GCG
uniprot id: A0A7E6DHG7
uniprot id: A0A7E6DHL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

89673:PIK3IP1
gene id: 89673:PIK3IP1
uniprot id: A0A6J2MY22
uniprot id: A0A6J2N2L3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TNFRSF19
gene id: 89673:TNFRSF19
uniprot id: A0A7E6CJK3
uniprot id: A0A7E6CJN3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SRPX2
gene id: 89673:SRPX2
uniprot id: A0A6J2MFN7
names: Caution
names: Subcellular Location Annotation
messages: Cell surface
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Synapse

89673:SERPINB7
gene id: 89673:SERPINB7
uniprot id: A0A6J2MMS7
names: Similarity
messages: Belongs to the serpin family.

89673:GALR3
gene id: 89673:GALR3
uniprot id: A0A6J2N9U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

89673:JOSD2
gene id: 89673:JOSD2
uniprot id: A0A7E6CNI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:MDH1
gene id: 89673:MDH1
uniprot id: A0A6J2LV44
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Homodimer.

89673:PTP4A2
gene id: 89673:PTP4A2
uniprot id: A0A6J2LPP0
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

89673:HTR4
gene id: 89673:HTR4
uniprot id: A0A7E6CSH4
uniprot id: A0A7E6CSS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

89673:ATP6V1B2
gene id: 89673:ATP6V1B2
uniprot id: A0A6J2M8T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

89673:LOC114500520
gene id: 89673:LOC114500520
uniprot id: A0A6J2M4P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HADH
gene id: 89673:HADH
uniprot id: A0A6J2L410
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

89673:NATD1
gene id: 89673:NATD1
uniprot id: A0A6J2NES5
names: Similarity
messages: Belongs to the NATD1 family.

89673:CRYGS
gene id: 89673:CRYGS
uniprot id: A0A6J2KYN6
uniprot id: A0A7E6D338
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

89673:EXOC5
gene id: 89673:EXOC5
uniprot id: A0A6J2L6T6
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

89673:ANTKMT
gene id: 89673:ANTKMT
uniprot id: A0A6J2M3Z1
uniprot id: A0A7E6DDN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

89673:MOCS2
gene id: 89673:MOCS2
uniprot id: A0A6J2MYJ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the small subunit (MOCS2A) from an overlapping reading frame.
messages: cytosol

89673:NEMP1
gene id: 89673:NEMP1
uniprot id: A0A6J2N870
uniprot id: A0A7E6D8R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

89673:RPL35
gene id: 89673:RPL35
uniprot id: A0A6J2LX87
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

89673:CCNL2
gene id: 89673:CCNL2
uniprot id: A0A6J2LRX5
uniprot id: A0A6J2LV73
names: Similarity
messages: Belongs to the cyclin family.

89673:MFAP3
gene id: 89673:MFAP3
uniprot id: A0A6J2MWV5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:GFM2
gene id: 89673:GFM2
uniprot id: A0A6J2KX06
uniprot id: A0A7E6DAE8
uniprot id: A0A7E6DAH5
uniprot id: A0A7E6DAS2
uniprot id: A0A7E6DBK1
uniprot id: A0A7E6DBK6
uniprot id: A0A7E6DD58
uniprot id: A0A7E6DD59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

89673:KCND2
gene id: 89673:KCND2
uniprot id: A0A6J2MVM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.2/KCND2 sub-subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite
messages: dendritic spine

89673:AQP2
gene id: 89673:AQP2
uniprot id: A0A6J2N762
uniprot id: A0A7E6D6P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

89673:PITX3
gene id: 89673:PITX3
uniprot id: A0A6J2LUS0
names: Subcellular Location Annotation
messages: Nucleus

89673:GAPVD1
gene id: 89673:GAPVD1
uniprot id: A0A6J2L1R5
uniprot id: A0A6J2L1T6
uniprot id: A0A6J2L1W2
uniprot id: A0A6J2L2H1
uniprot id: A0A6J2L672
uniprot id: A0A7E6DGD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAPVD1 family.
messages: Membrane

89673:SLC16A1
gene id: 89673:SLC16A1
uniprot id: A0A6J2KV87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

89673:DMRT3
gene id: 89673:DMRT3
uniprot id: A0A6J2MK64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

89673:SHTN1
gene id: 89673:SHTN1
uniprot id: A0A6J2LPS9
uniprot id: A0A6J2LTX9
uniprot id: A0A7E6DWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shootin family.
messages: axon
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

89673:MAGI2
gene id: 89673:MAGI2
uniprot id: A0A6J2MPR4
uniprot id: A0A6J2MUD3
uniprot id: A0A7E6CI03
names: Subcellular Location Annotation
messages: Membrane

89673:SRP68
gene id: 89673:SRP68
uniprot id: A0A6J2MH24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

89673:PLRG1
gene id: 89673:PLRG1
uniprot id: A0A6J2M7P1
uniprot id: A0A6J2M916
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

89673:VIM
gene id: 89673:VIM
uniprot id: A0A6J2L4P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Cell membrane
messages: Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
messages: Membrane
messages: Nucleus matrix
messages: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.

89673:TAFA2
gene id: 89673:TAFA2
uniprot id: A0A6J2N9S8
names: Similarity
messages: Belongs to the TAFA family.

89673:GPAM
gene id: 89673:GPAM
uniprot id: A0A6J2LQN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
messages: Mitochondrion outer membrane

89673:PRKCH
gene id: 89673:PRKCH
uniprot id: A0A6J2LAB6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentiation. Associates with the cyclin CCNE1-CDK2-CDKN1B complex and inhibits CDK2 kinase activity, leading to RB1 dephosphorylation and thereby G1 arrest in keratinocytes. In association with RALA activates actin depolymerization, which is necessary for keratinocyte differentiation. In the pre-B cell receptor signaling, functions downstream of BLNK by up-regulating IRF4, which in turn activates L chain gene rearrangement. Regulates epithelial tight junctions (TJs) by phosphorylating occludin (OCLN) on threonine residues, which is necessary for the assembly and maintenance of TJs. In association with PLD2 and via TLR4 signaling, is involved in lipopolysaccharide (LPS)-induced RGS2 down-regulation and foam cell formation. Upon PMA stimulation, mediates glioblastoma cell proliferation by activating the mTOR pathway, the PI3K/AKT pathway and the ERK1-dependent phosphorylation of ELK1. Involved in the protection of glioblastoma cells from irradiation-induced apoptosis by preventing caspase-9 activation. In camptothecin-treated MCF-7 cells, regulates NF-kappa-B upstream signaling by activating IKBKB, and confers protection against DNA damage-induced apoptosis.
messages: Cytoplasm
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine. Three specific sites; Thr-513 (activation loop of the kinase domain), Thr-656 (turn motif) and Ser-675 (hydrophobic region), need to be phosphorylated for its full activation.

89673:LOC114497821
gene id: 89673:LOC114497821
uniprot id: A0A6J2LUI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.
messages: Nucleus
messages: kinetochore

89673:GRHL1
gene id: 89673:GRHL1
uniprot id: A0A6J2LY20
uniprot id: A0A7E6DWX5
uniprot id: A0A7E6DXS5
names: Subcellular Location Annotation
messages: Nucleus

89673:RGS1
gene id: 89673:RGS1
uniprot id: A0A6J2NA96
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytosol

89673:FBXO34
gene id: 89673:FBXO34
uniprot id: A0A6J2L4H3
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

89673:GTF3C5
gene id: 89673:GTF3C5
uniprot id: A0A6J2LZF0
names: Subcellular Location Annotation
messages: Nucleus

89673:STC1
gene id: 89673:STC1
uniprot id: A0A6J2MDQ2
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

89673:LOC118499835
gene id: 89673:LOC118499835
uniprot id: A0A7E6DH76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

89673:MAST3
gene id: 89673:MAST3
uniprot id: A0A6J2M5V0
uniprot id: A0A6J2M7A1
uniprot id: A0A6J2M7Q2
uniprot id: A0A6J2MAL8
uniprot id: A0A6J2MB51
uniprot id: A0A7E6EAR1
uniprot id: A0A7E6EAY1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

89673:TTC19
gene id: 89673:TTC19
uniprot id: A0A6J2NDK6
uniprot id: A0A7E6EB08
uniprot id: A0A7E6ECK8
uniprot id: A0A7E6ECX6
names: Similarity
messages: Belongs to the TTC19 family.

89673:CBFA2T3
gene id: 89673:CBFA2T3
uniprot id: A0A6J2KQK3
uniprot id: A0A6J2KR56
uniprot id: A0A7E6CMY3
names: Similarity
messages: Belongs to the CBFA2T family.

89673:BMP6
gene id: 89673:BMP6
uniprot id: A0A6J2LRU1
names: Similarity
messages: Belongs to the TGF-beta family.

89673:MPC1L
gene id: 89673:MPC1L
uniprot id: A0A6J2MMX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

89673:LOC114490157
gene id: 89673:LOC114490157
uniprot id: A0A6J2L2N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TAT
gene id: 89673:TAT
uniprot id: A0A6J2KX40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

89673:ATP6V0D2
gene id: 89673:ATP6V0D2
uniprot id: A0A6J2M9B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

89673:LOC114490173
gene id: 89673:LOC114490173
uniprot id: A0A6J2KWW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114500549
gene id: 89673:LOC114500549
uniprot id: A0A7E6E0X2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:CRYBA4
gene id: 89673:CRYBA4
uniprot id: A0A6J2N0P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

89673:LOC114507469
gene id: 89673:LOC114507469
uniprot id: A0A6J2MT07
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:LOC114500179
gene id: 89673:LOC114500179
uniprot id: A0A6J2M3F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:GLG1
gene id: 89673:GLG1
uniprot id: A0A6J2NDG6
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

89673:MTCL1
gene id: 89673:MTCL1
uniprot id: A0A6J2MQB8
uniprot id: A0A7E6CDX9
uniprot id: A0A7E6CDY0
uniprot id: A0A7E6CDY5
uniprot id: A0A7E6CE42
uniprot id: A0A7E6CE47
uniprot id: A0A7E6CEM9
uniprot id: A0A7E6CEN4
uniprot id: A0A7E6CG74
uniprot id: A0A7E6CG77
names: Similarity
messages: Belongs to the SOGA family.

89673:LOC114499967
gene id: 89673:LOC114499967
uniprot id: A0A6J2M0F7
uniprot id: A0A6J2M2M3
uniprot id: A0A7E6E2N8
uniprot id: A0A7E6E381
uniprot id: A0A7E6E482
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:ING1
gene id: 89673:ING1
uniprot id: A0A6J2MSA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

89673:COG1
gene id: 89673:COG1
uniprot id: A0A6J2M8T7
uniprot id: A0A6J2MBK9
uniprot id: A0A7E6ECJ9
uniprot id: A0A7E6ED42
uniprot id: A0A7E6EE35
names: Similarity
messages: Belongs to the COG1 family.

89673:RITA1
gene id: 89673:RITA1
uniprot id: A0A6J2MWU2
uniprot id: A0A7E6CUH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RITA family.
messages: Cytoplasm
messages: Interacts with RBPJ/RBPSUH.
messages: Nucleus
messages: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

89673:PYCR1
gene id: 89673:PYCR1
uniprot id: A0A6J2MDB8
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

89673:FAAH
gene id: 89673:FAAH
uniprot id: A0A6J2LPK8
names: Similarity
messages: Belongs to the amidase family.

89673:TOR4A
gene id: 89673:TOR4A
uniprot id: A0A6J2MRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Membrane

89673:FGFR1
gene id: 89673:FGFR1
uniprot id: A0A6J2MRG6
uniprot id: A0A6J2MW84
uniprot id: A0A7E6CKP2
uniprot id: A0A7E6CKP6
uniprot id: A0A7E6CKQ3
uniprot id: A0A7E6CKQ4
uniprot id: A0A7E6CKQ8
uniprot id: A0A7E6CKQ9
uniprot id: A0A7E6CKS3
uniprot id: A0A7E6CKS6
uniprot id: A0A7E6CMV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Nucleus
messages: Vesicle
messages: cytosol

89673:ZBTB8OS
gene id: 89673:ZBTB8OS
uniprot id: A0A6J2LIZ4
uniprot id: A0A6J2LK73
uniprot id: A0A6J2LNY3
uniprot id: A0A7E6DR00
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

89673:TNFRSF9
gene id: 89673:TNFRSF9
uniprot id: A0A7E6DP96
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114503801
gene id: 89673:LOC114503801
uniprot id: A0A6J2MAW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Interacts with ASTL.
messages: Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.

89673:LOC114490202
gene id: 89673:LOC114490202
uniprot id: A0A6J2L0V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TECRL
gene id: 89673:TECRL
uniprot id: A0A6J2LCK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

89673:LOC114496116
gene id: 89673:LOC114496116
uniprot id: A0A6J2LJU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

89673:ATL1
gene id: 89673:ATL1
uniprot id: A0A6J2LCU8
uniprot id: A0A6J2LDW2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

89673:CDK7
gene id: 89673:CDK7
uniprot id: A0A6J2MSP2
uniprot id: A0A6J2MSQ0
uniprot id: A0A7E6DA88
uniprot id: A0A7E6DD38
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

89673:PAN3
gene id: 89673:PAN3
uniprot id: A0A6J2KYA1
uniprot id: A0A7E6D4P3
uniprot id: A0A7E6D4S5
uniprot id: A0A7E6D4V7
uniprot id: A0A7E6D7I0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

89673:CTNNBIP1
gene id: 89673:CTNNBIP1
uniprot id: A0A6J2LP43
names: Similarity
messages: Belongs to the CTNNBIP1 family.

89673:VEPH1
gene id: 89673:VEPH1
uniprot id: A0A6J2L3Y4
names: Similarity
messages: Belongs to the MELT/VEPH family.

89673:LOC114499826
gene id: 89673:LOC114499826
uniprot id: A0A6J2M233
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

89673:ECSIT
gene id: 89673:ECSIT
uniprot id: A0A6J2M7I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development.
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the ECSIT family.
messages: Cytoplasm
messages: Mitochondrion
messages: Nucleus

89673:UBE2G1
gene id: 89673:UBE2G1
uniprot id: A0A6J2NIH8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:CXCL9
gene id: 89673:CXCL9
uniprot id: A0A7E6DGW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

89673:GGT1
gene id: 89673:GGT1
uniprot id: A0A6J2MU28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:VWC2
gene id: 89673:VWC2
uniprot id: A0A7E6CHB3
names: Subcellular Location Annotation
messages: Synapse

89673:LOC114508519
gene id: 89673:LOC114508519
uniprot id: A0A7E6CK62
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

89673:LHX6
gene id: 89673:LHX6
uniprot id: A0A6J2N3H4
uniprot id: A0A6J2NAP8
uniprot id: A0A7E6DG85
uniprot id: A0A7E6DGB2
uniprot id: A0A7E6DGF7
uniprot id: A0A7E6DGG5
names: Subcellular Location Annotation
messages: Nucleus

89673:SHROOM3
gene id: 89673:SHROOM3
uniprot id: A0A6J2L5M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

89673:PHC3
gene id: 89673:PHC3
uniprot id: A0A6J2KX10
uniprot id: A0A6J2KYR2
uniprot id: A0A7E6D2Q4
uniprot id: A0A7E6D2R4
uniprot id: A0A7E6D2R9
uniprot id: A0A7E6D2T4
uniprot id: A0A7E6D2W6
uniprot id: A0A7E6D3G5
uniprot id: A0A7E6D3H1
names: Subcellular Location Annotation
messages: Nucleus

89673:SAP30
gene id: 89673:SAP30
uniprot id: A0A6J2ME02
names: Similarity
messages: Belongs to the SAP30 family.

89673:OPN3
gene id: 89673:OPN3
uniprot id: A0A6J2N9W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

89673:LOC114505267
gene id: 89673:LOC114505267
uniprot id: A0A7E6CZW1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:FOXQ1
gene id: 89673:FOXQ1
uniprot id: A0A6J2LPI0
names: Subcellular Location Annotation
messages: Nucleus

89673:GDNF
gene id: 89673:GDNF
uniprot id: A0A6J2MQN6
uniprot id: A0A7E6D9T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

89673:DDX10
gene id: 89673:DDX10
uniprot id: A0A6J2LXV1
names: Similarity
messages: Belongs to the DEAD box helicase family.

89673:PES1
gene id: 89673:PES1
uniprot id: A0A6J2MX66
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Chromosome
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome. Interacts with IRS1 and UBTF. May interact with MAP1B.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: Sumoylated.
messages: nucleolus
messages: nucleoplasm

89673:MAN1A2
gene id: 89673:MAN1A2
uniprot id: A0A6J2KV80
uniprot id: A0A7E6CW73
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

89673:HMGN5
gene id: 89673:HMGN5
uniprot id: A0A6J2MGF2
uniprot id: A0A7E6CZU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

89673:KCMF1
gene id: 89673:KCMF1
uniprot id: A0A6J2LWS8
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

89673:UBALD1
gene id: 89673:UBALD1
uniprot id: A0A6J2LYV6
names: Similarity
messages: Belongs to the UBALD family.

89673:DXO
gene id: 89673:DXO
uniprot id: A0A6J2LDP3
uniprot id: A0A7E6DKW8
uniprot id: A0A7E6DKX5
uniprot id: A0A7E6DL96
uniprot id: A0A7E6DLB1
uniprot id: A0A7E6DLM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

89673:SOX9
gene id: 89673:SOX9
uniprot id: A0A6J2M588
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114495335
gene id: 89673:LOC114495335
uniprot id: A0A6J2LG67
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

89673:PDE8B
gene id: 89673:PDE8B
uniprot id: A0A6J2MTW0
uniprot id: A0A6J2MYU7
uniprot id: A0A6J2MYV9
uniprot id: A0A7E6DAH8
uniprot id: A0A7E6DAL1
uniprot id: A0A7E6DD71
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:VAMP4
gene id: 89673:VAMP4
uniprot id: A0A6J2N2I0
uniprot id: A0A7E6CV67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

89673:DACT3
gene id: 89673:DACT3
uniprot id: A0A6J2N7D1
names: Similarity
messages: Belongs to the dapper family.

89673:NPHS2
gene id: 89673:NPHS2
uniprot id: A0A6J2N2Y2
uniprot id: A0A7E6CX00
names: Similarity
messages: Belongs to the band 7/mec-2 family.

89673:GJA1
gene id: 89673:GJA1
uniprot id: A0A6J2LFL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins. Interacts with SGSM3 (By similarity). Interacts with RIC1/CIP150 (By similarity). Interacts with CNST and CSNK1D (By similarity). Interacts (via C-terminus) with TJP1. Interacts (via C-terminus) with SRC (via SH3 domain). Interacts (not ubiquitinated) with UBQLN4 (via UBA domain) (By similarity). Interacts with NOV. Interacts with TMEM65.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Endoplasmic reticulum
messages: Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract. May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles.
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:CCN3
gene id: 89673:CCN3
uniprot id: A0A6J2NB71
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:LOC114491854
gene id: 89673:LOC114491854
uniprot id: A0A7E6EAL5
names: Subcellular Location Annotation
messages: Membrane

89673:SLC10A1
gene id: 89673:SLC10A1
uniprot id: A0A6J2L977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

89673:GABRA5
gene id: 89673:GABRA5
uniprot id: A0A6J2KZJ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:CSNK2A2
gene id: 89673:CSNK2A2
uniprot id: A0A6J2KWA0
uniprot id: A0A7E6CLL9
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:ALDOC
gene id: 89673:ALDOC
uniprot id: A0A6J2M871
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

89673:HMGN2
gene id: 89673:HMGN2
uniprot id: A0A6J2LLX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

89673:TUT4
gene id: 89673:TUT4
uniprot id: A0A7E6DRY6
uniprot id: A0A7E6DS11
uniprot id: A0A7E6DS16
uniprot id: A0A7E6DSL2
uniprot id: A0A7E6DSL6
uniprot id: A0A7E6DSQ2
uniprot id: A0A7E6DT42
uniprot id: A0A7E6DT49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

89673:VILL
gene id: 89673:VILL
uniprot id: A0A6J2M8B4
uniprot id: A0A7E6E5T7
names: Similarity
messages: Belongs to the villin/gelsolin family.

89673:UNC5C
gene id: 89673:UNC5C
uniprot id: A0A6J2LBZ7
uniprot id: A0A7E6DTA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

89673:RNASE9
gene id: 89673:RNASE9
uniprot id: A0A6J2KXI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Does not exhibit any ribonuclease activity.
messages: Secreted

89673:GGH
gene id: 89673:GGH
uniprot id: A0A6J2ND50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

89673:NFIL3
gene id: 89673:NFIL3
uniprot id: A0A6J2N601
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. Protects pro-B cells from programmed cell death.
messages: Belongs to the bZIP family. NFIL3 subfamily.
messages: Homodimer. Binds DNA as a dimer.
messages: Nucleus

89673:MPPED2
gene id: 89673:MPPED2
uniprot id: A0A6J2LVH1
uniprot id: A0A7E6E187
names: Similarity
messages: Belongs to the UPF0046 family.

89673:FOXJ1
gene id: 89673:FOXJ1
uniprot id: A0A6J2M705
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114498954
gene id: 89673:LOC114498954
uniprot id: A0A7E6E067
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:GSPT2
gene id: 89673:GSPT2
uniprot id: A0A6J2MK84
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

89673:DOCK1
gene id: 89673:DOCK1
uniprot id: A0A6J2LNZ8
uniprot id: A0A7E6DVZ4
names: Similarity
messages: Belongs to the DOCK family.

89673:IL17RA
gene id: 89673:IL17RA
uniprot id: A0A6J2MRK7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:SH3YL1
gene id: 89673:SH3YL1
uniprot id: A0A6J2M065
uniprot id: A0A7E6DWA0
names: Similarity
names: Subunit
messages: Belongs to the SH3YL1 family.
messages: Interacts with SH3D19.

89673:MPC2
gene id: 89673:MPC2
uniprot id: A0A6J2N403
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

89673:TMEM150B
gene id: 89673:TMEM150B
uniprot id: A0A6J2MXX9
names: Subcellular Location Annotation
messages: Membrane

89673:CDC26
gene id: 89673:CDC26
uniprot id: A0A6J2MAR3
names: Function
names: Similarity
messages: Belongs to the CDC26 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

89673:LOC114506555
gene id: 89673:LOC114506555
uniprot id: A0A6J2MQ36
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

89673:MON1B
gene id: 89673:MON1B
uniprot id: A0A6J2KQP8
uniprot id: A0A6J2KUM5
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

89673:TMEM255B
gene id: 89673:TMEM255B
uniprot id: A0A6J2MST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

89673:HTR1E
gene id: 89673:HTR1E
uniprot id: A0A6J2LG22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:LOC114500818
gene id: 89673:LOC114500818
uniprot id: A0A6J2M1G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC27A3
gene id: 89673:SLC27A3
uniprot id: A0A6J2KTH0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:TIMM23
gene id: 89673:TIMM23
uniprot id: A0A6J2LLR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

89673:FNBP1L
gene id: 89673:FNBP1L
uniprot id: A0A6J2LVA3
uniprot id: A0A6J2LVJ8
uniprot id: A0A7E6DT08
uniprot id: A0A7E6DTT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Vesicle
messages: cell cortex
messages: cytoskeleton

89673:TRPM6
gene id: 89673:TRPM6
uniprot id: A0A7E6DF32
uniprot id: A0A7E6DF71
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

89673:DNAH1
gene id: 89673:DNAH1
uniprot id: A0A7E6E592
uniprot id: A0A7E6E6S8
uniprot id: A0A7E6E6X9
names: Similarity
messages: Belongs to the dynein heavy chain family.

89673:TEKT2
gene id: 89673:TEKT2
uniprot id: A0A6J2LNE6
uniprot id: A0A7E6DSA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

89673:SEC61G
gene id: 89673:SEC61G
uniprot id: A0A6J2MV53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:MYO18B
gene id: 89673:MYO18B
uniprot id: A0A7E6CRB1
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:REXO4
gene id: 89673:REXO4
uniprot id: A0A6J2N152
uniprot id: A0A7E6DGZ6
names: Similarity
messages: Belongs to the REXO4 family.

89673:MTMR9
gene id: 89673:MTMR9
uniprot id: A0A6J2ME64
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

89673:LOC114489508
gene id: 89673:LOC114489508
uniprot id: A0A7E6CXE8
names: Subcellular Location Annotation
messages: Membrane

89673:JRK
gene id: 89673:JRK
uniprot id: A0A6J2NBY2
names: Subcellular Location Annotation
messages: Nucleus

89673:CFB
gene id: 89673:CFB
uniprot id: A0A6J2LGS1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:TRIP12
gene id: 89673:TRIP12
uniprot id: A0A6J2L980
uniprot id: A0A6J2L985
uniprot id: A0A6J2L988
uniprot id: A0A6J2L9Q4
uniprot id: A0A6J2L9R1
uniprot id: A0A6J2LB22
uniprot id: A0A6J2LDS7
uniprot id: A0A7E6DHT2
uniprot id: A0A7E6DHX3
uniprot id: A0A7E6DHX9
uniprot id: A0A7E6DHZ7
uniprot id: A0A7E6DI02
uniprot id: A0A7E6DI17
uniprot id: A0A7E6DI22
uniprot id: A0A7E6DI45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins.
messages: nucleoplasm

89673:MAT2A
gene id: 89673:MAT2A
uniprot id: A0A6J2LYQ7
uniprot id: A0A7E6DYL0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

89673:LOC114500563
gene id: 89673:LOC114500563
uniprot id: A0A6J2LZA1
uniprot id: A0A6J2M0G9
uniprot id: A0A7E6DYN2
names: Similarity
messages: Belongs to the SNF7 family.

89673:FGF22
gene id: 89673:FGF22
uniprot id: A0A6J2MCQ4
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:TEAD4
gene id: 89673:TEAD4
uniprot id: A0A7E6D564
uniprot id: A0A7E6D5B9
names: Subcellular Location Annotation
messages: Nucleus

89673:TMEM150A
gene id: 89673:TMEM150A
uniprot id: A0A6J2LRF8
uniprot id: A0A7E6DZH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRAM/TMEM150 family.
messages: Cell membrane
messages: Membrane

89673:LOC114503695
gene id: 89673:LOC114503695
uniprot id: A0A7E6EBM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PLXNA3
gene id: 89673:PLXNA3
uniprot id: A0A6J2MFB5
uniprot id: A0A7E6D0D8
uniprot id: A0A7E6D0K7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TRIM72
gene id: 89673:TRIM72
uniprot id: A0A6J2MJU6
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle membrane
messages: sarcolemma

89673:TMEM132C
gene id: 89673:TMEM132C
uniprot id: A0A7E6CXL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

89673:KRT74
gene id: 89673:KRT74
uniprot id: A0A6J2N6R9
names: Similarity
messages: Belongs to the intermediate filament family.

89673:DGAT2L6
gene id: 89673:DGAT2L6
uniprot id: A0A6J2MKL8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:PNKD
gene id: 89673:PNKD
uniprot id: A0A6J2LKP5
uniprot id: A0A6J2LLG5
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

89673:MED6
gene id: 89673:MED6
uniprot id: A0A7E6CMU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

89673:RDH11
gene id: 89673:RDH11
uniprot id: A0A6J2L978
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:SEC24B
gene id: 89673:SEC24B
uniprot id: A0A6J2L802
uniprot id: A0A7E6DQ40
uniprot id: A0A7E6DQ59
uniprot id: A0A7E6DQT9
uniprot id: A0A7E6DQV5
uniprot id: A0A7E6DQV8
uniprot id: A0A7E6DRB1
uniprot id: A0A7E6DRD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

89673:LOC114488605
gene id: 89673:LOC114488605
uniprot id: A0A6J2KRW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

89673:INA
gene id: 89673:INA
uniprot id: A0A6J2LPF2
names: Similarity
messages: Belongs to the intermediate filament family.

89673:LOC114500786
gene id: 89673:LOC114500786
uniprot id: A0A6J2M261
names: Similarity
messages: Belongs to the calcitonin family.

89673:CARMIL1
gene id: 89673:CARMIL1
uniprot id: A0A7E6CV13
uniprot id: A0A7E6CV23
uniprot id: A0A7E6CVT6
uniprot id: A0A7E6CXU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

89673:LOC114508130
gene id: 89673:LOC114508130
uniprot id: A0A6J2MR07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:SPEG
gene id: 89673:SPEG
uniprot id: A0A6J2LH89
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

89673:MFSD3
gene id: 89673:MFSD3
uniprot id: A0A6J2NCM9
names: Subcellular Location Annotation
messages: Membrane

89673:DPYSL3
gene id: 89673:DPYSL3
uniprot id: A0A6J2MV29
uniprot id: A0A6J2MZN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Cytoplasm
messages: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
messages: growth cone

89673:NPM2
gene id: 89673:NPM2
uniprot id: A0A6J2MCZ4
names: Similarity
messages: Belongs to the nucleoplasmin family.

89673:MTERF3
gene id: 89673:MTERF3
uniprot id: A0A6J2NCT1
names: Similarity
messages: Belongs to the mTERF family.

89673:SNAP91
gene id: 89673:SNAP91
uniprot id: A0A6J2LG73
uniprot id: A0A6J2LHE6
uniprot id: A0A7E6DME0
uniprot id: A0A7E6DME5
uniprot id: A0A7E6DME6
uniprot id: A0A7E6DMF0
uniprot id: A0A7E6DMF1
uniprot id: A0A7E6DMF3
uniprot id: A0A7E6DMF7
uniprot id: A0A7E6DMV5
uniprot id: A0A7E6DMW0
uniprot id: A0A7E6DMY1
uniprot id: A0A7E6DMY6
uniprot id: A0A7E6DN74
uniprot id: A0A7E6DN78
uniprot id: A0A7E6DN83
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

89673:RIPK3
gene id: 89673:RIPK3
uniprot id: A0A6J2L2Z1
uniprot id: A0A7E6E2B2
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114515045
gene id: 89673:LOC114515045
uniprot id: A0A7E6EBM1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

89673:SCAMP5
gene id: 89673:SCAMP5
uniprot id: A0A6J2L7A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

89673:LOC118496903
gene id: 89673:LOC118496903
uniprot id: A0A7E6CIG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

89673:MRPL35
gene id: 89673:MRPL35
uniprot id: A0A6J2M1I1
uniprot id: A0A7E6DZ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

89673:ATP13A4
gene id: 89673:ATP13A4
uniprot id: A0A6J2KYV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

89673:ASAH1
gene id: 89673:ASAH1
uniprot id: A0A6J2MQG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acid ceramidase family.
messages: Heterodimer.
messages: Lysosome

89673:FUT9
gene id: 89673:FUT9
uniprot id: A0A6J2LDJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

89673:TOM1
gene id: 89673:TOM1
uniprot id: A0A6J2NCE4
uniprot id: A0A7E6D876
names: Similarity
messages: Belongs to the TOM1 family.

89673:LOC118497701
gene id: 89673:LOC118497701
uniprot id: A0A7E6CPU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

89673:TMEM245
gene id: 89673:TMEM245
uniprot id: A0A6J2N4D5
uniprot id: A0A7E6DFU5
uniprot id: A0A7E6DFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

89673:LOC114512477
gene id: 89673:LOC114512477
uniprot id: A0A6J2N416
uniprot id: A0A7E6D163
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:DARS1
gene id: 89673:DARS1
uniprot id: A0A7E6DKP6
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

89673:LOC114489443
gene id: 89673:LOC114489443
uniprot id: A0A6J2KV12
names: Subcellular Location Annotation
messages: Membrane

89673:PYGM
gene id: 89673:PYGM
uniprot id: A0A6J2LZI8
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

89673:LOC114492701
gene id: 89673:LOC114492701
uniprot id: A0A6J2L7Q1
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:CRYZ
gene id: 89673:CRYZ
uniprot id: A0A6J2LNW6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

89673:LOC114507470
gene id: 89673:LOC114507470
uniprot id: A0A6J2MLP6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:SLC18A2
gene id: 89673:SLC18A2
uniprot id: A0A6J2LSY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

89673:AMHR2
gene id: 89673:AMHR2
uniprot id: A0A6J2N9E3
uniprot id: A0A7E6D6H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.

89673:NIF3L1
gene id: 89673:NIF3L1
uniprot id: A0A6J2LAE8
uniprot id: A0A7E6DIU6
uniprot id: A0A7E6DJ22
uniprot id: A0A7E6DJ33
uniprot id: A0A7E6DJ86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Cytoplasm
messages: Homodimer. Interacts with COPS2. Interacts with THOC7.
messages: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
messages: Nucleus

89673:MRPL52
gene id: 89673:MRPL52
uniprot id: A0A6J2L4G6
uniprot id: A0A6J2L6S0
uniprot id: A0A6J2L953
uniprot id: A0A6J2LAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

89673:MGAT5B
gene id: 89673:MGAT5B
uniprot id: A0A6J2MDJ1
uniprot id: A0A6J2ME41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:PDCL2
gene id: 89673:PDCL2
uniprot id: A0A6J2L8V4
names: Similarity
messages: Belongs to the phosducin family.

89673:LOC114507396
gene id: 89673:LOC114507396
uniprot id: A0A6J2MLK7
uniprot id: A0A7E6CL14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114490985
gene id: 89673:LOC114490985
uniprot id: A0A7E6D9P1
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

89673:ATPSCKMT
gene id: 89673:ATPSCKMT
uniprot id: A0A6J2N8Y7
uniprot id: A0A6J2NDX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

89673:MEIS3
gene id: 89673:MEIS3
uniprot id: A0A6J2N0D7
uniprot id: A0A6J2N5U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

89673:DOCK3
gene id: 89673:DOCK3
uniprot id: A0A6J2M439
uniprot id: A0A7E6E3N2
uniprot id: A0A7E6E4A1
uniprot id: A0A7E6E550
uniprot id: A0A7E6E554
uniprot id: A0A7E6E596
names: Similarity
messages: Belongs to the DOCK family.

89673:PPFIA1
gene id: 89673:PPFIA1
uniprot id: A0A7E6E2E4
uniprot id: A0A7E6E2X9
uniprot id: A0A7E6E2Y3
uniprot id: A0A7E6E362
uniprot id: A0A7E6E365
uniprot id: A0A7E6E3V0
uniprot id: A0A7E6E3W0
uniprot id: A0A7E6E3W8
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

89673:LOC114490193
gene id: 89673:LOC114490193
uniprot id: A0A6J2KXH6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CBL
gene id: 89673:CBL
uniprot id: A0A6J2M281
uniprot id: A0A7E6DYN1
uniprot id: A0A7E6DZJ2
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

89673:KAT8
gene id: 89673:KAT8
uniprot id: A0A6J2LKY5
uniprot id: A0A6J2LKZ2
uniprot id: A0A7E6DDY6
uniprot id: A0A7E6DDZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

89673:LOC114498874
gene id: 89673:LOC114498874
uniprot id: A0A6J2LSE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ACTR3B
gene id: 89673:ACTR3B
uniprot id: A0A6J2MPZ3
uniprot id: A0A7E6CJ72
uniprot id: A0A7E6CJ92
uniprot id: A0A7E6CJC7
names: Similarity
messages: Belongs to the actin family.

89673:KIT
gene id: 89673:KIT
uniprot id: A0A6J2L2G1
uniprot id: A0A6J2L634
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

89673:LOC114494184
gene id: 89673:LOC114494184
uniprot id: A0A7E6DLV2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

89673:P2RY1
gene id: 89673:P2RY1
uniprot id: A0A6J2L023
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:GATM
gene id: 89673:GATM
uniprot id: A0A6J2L8K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine.
messages: Homodimer.
messages: Mitochondrion inner membrane

89673:GTF2F1
gene id: 89673:GTF2F1
uniprot id: A0A6J2MAD2
uniprot id: A0A7E6EA49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

89673:BRPF1
gene id: 89673:BRPF1
uniprot id: A0A7E6E5U5
names: Subcellular Location Annotation
messages: Nucleus

89673:BST1
gene id: 89673:BST1
uniprot id: A0A6J2LA94
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

89673:QSOX1
gene id: 89673:QSOX1
uniprot id: A0A6J2N4G7
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

89673:ERG28
gene id: 89673:ERG28
uniprot id: A0A6J2L658
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:CCND1
gene id: 89673:CCND1
uniprot id: A0A6J2M5A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

89673:SLC15A5
gene id: 89673:SLC15A5
uniprot id: A0A6J2N6P4
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

89673:DYNLT3
gene id: 89673:DYNLT3
uniprot id: A0A6J2MFY3
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

89673:TAPT1
gene id: 89673:TAPT1
uniprot id: A0A7E6D9D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

89673:EYA4
gene id: 89673:EYA4
uniprot id: A0A7E6DNA8
uniprot id: A0A7E6DNC6
uniprot id: A0A7E6DND1
uniprot id: A0A7E6DNR6
uniprot id: A0A7E6DNS1
uniprot id: A0A7E6DNZ1
uniprot id: A0A7E6DP98
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Nucleus

89673:DMPK
gene id: 89673:DMPK
uniprot id: A0A6J2N042
uniprot id: A0A6J2N1S9
uniprot id: A0A6J2N1T4
uniprot id: A0A6J2N6E7
uniprot id: A0A7E6CPW6
uniprot id: A0A7E6CQ16
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.

89673:GTF2B
gene id: 89673:GTF2B
uniprot id: A0A6J2LSD3
names: Similarity
messages: Belongs to the TFIIB family.

89673:CPA1
gene id: 89673:CPA1
uniprot id: A0A6J2MQG3
names: Similarity
messages: Belongs to the peptidase M14 family.

89673:C3H9orf64
gene id: 89673:C3H9orf64
uniprot id: A0A6J2MZD4
uniprot id: A0A7E6DF74
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

89673:GNG4
gene id: 89673:GNG4
uniprot id: A0A6J2NB36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:MTRF1
gene id: 89673:MTRF1
uniprot id: A0A6J2MRN5
uniprot id: A0A7E6CJV8
uniprot id: A0A7E6CJX9
uniprot id: A0A7E6CJY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

89673:SDHB
gene id: 89673:SDHB
uniprot id: A0A6J2LPY6
uniprot id: A0A7E6DQ28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

89673:C4H2orf88
gene id: 89673:C4H2orf88
uniprot id: A0A7E6DJ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small membrane AKAP family.
messages: Cell membrane
messages: Membrane

89673:SMIM7
gene id: 89673:SMIM7
uniprot id: A0A6J2MCR5
names: Similarity
messages: Belongs to the SMIM7 family.

89673:NAXE
gene id: 89673:NAXE
uniprot id: A0A6J2KUA3
uniprot id: A0A7E6CXI5
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis.
messages: Homodimer. Interacts with APOA1 and APOA2.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Secreted
messages: Undergoes physiological phosphorylation during sperm capacitation, downstream to PKA activation.

89673:SCUBE2
gene id: 89673:SCUBE2
uniprot id: A0A6J2M257
uniprot id: A0A7E6E0E8
uniprot id: A0A7E6E0S3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:FAM83F
gene id: 89673:FAM83F
uniprot id: A0A6J2N7R1
names: Similarity
messages: Belongs to the FAM83 family.

89673:PLEKHO1
gene id: 89673:PLEKHO1
uniprot id: A0A6J2KX73
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:ARSI
gene id: 89673:ARSI
uniprot id: A0A6J2N0V3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

89673:SCN8A
gene id: 89673:SCN8A
uniprot id: A0A7E6D6K0
uniprot id: A0A7E6D6M0
uniprot id: A0A7E6D6Q4
uniprot id: A0A7E6D790
uniprot id: A0A7E6D797
uniprot id: A0A7E6D9H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

89673:MYMK
gene id: 89673:MYMK
uniprot id: A0A6J2N831
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

89673:LOC114490006
gene id: 89673:LOC114490006
uniprot id: A0A6J2KYJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KRTAP type 3 family.
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

89673:SLC47A1
gene id: 89673:SLC47A1
uniprot id: A0A6J2NEZ4
uniprot id: A0A7E6ECV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

89673:LOC114503147
gene id: 89673:LOC114503147
uniprot id: A0A6J2MDH7
uniprot id: A0A7E6EA25
uniprot id: A0A7E6EB22
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:UHRF2
gene id: 89673:UHRF2
uniprot id: A0A6J2MYV6
uniprot id: A0A7E6DEU3
uniprot id: A0A7E6DEW4
names: Subcellular Location Annotation
messages: Nucleus

89673:LCA5L
gene id: 89673:LCA5L
uniprot id: A0A7E6D2U2
names: Similarity
messages: Belongs to the LCA5 family.

89673:TRAPPC4
gene id: 89673:TRAPPC4
uniprot id: A0A6J2M056
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

89673:LOC114493931
gene id: 89673:LOC114493931
uniprot id: A0A6J2LAM2
uniprot id: A0A7E6DLA0
uniprot id: A0A7E6DLN5
uniprot id: A0A7E6DM10
names: Similarity
messages: Belongs to the MHC class I family.

89673:THOC7
gene id: 89673:THOC7
uniprot id: A0A6J2M8G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

89673:SLC16A14
gene id: 89673:SLC16A14
uniprot id: A0A6J2LG65
uniprot id: A0A7E6DHU2
names: Subcellular Location Annotation
messages: Membrane

89673:GABRB1
gene id: 89673:GABRB1
uniprot id: A0A6J2L7I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:NLRP13
gene id: 89673:NLRP13
uniprot id: A0A6J2MY19
names: Similarity
messages: Belongs to the NLRP family.

89673:PARL
gene id: 89673:PARL
uniprot id: A0A6J2L3A1
names: Subcellular Location Annotation
messages: Membrane

89673:CD109
gene id: 89673:CD109
uniprot id: A0A6J2LLJ7
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

89673:LOC114495968
gene id: 89673:LOC114495968
uniprot id: A0A6J2LLM2
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

89673:EZR
gene id: 89673:EZR
uniprot id: A0A6J2LFV0
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

89673:PDIK1L
gene id: 89673:PDIK1L
uniprot id: A0A6J2LIX9
uniprot id: A0A6J2LMM3
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114500365
gene id: 89673:LOC114500365
uniprot id: A0A6J2LZT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NOG
gene id: 89673:NOG
uniprot id: A0A6J2M938
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
messages: Secreted

89673:LOC114501168
gene id: 89673:LOC114501168
uniprot id: A0A7E6DDF9
names: Similarity
messages: Belongs to the FAM136 family.

89673:TOP2A
gene id: 89673:TOP2A
uniprot id: A0A6J2M719
uniprot id: A0A6J2M9Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

89673:BRF1
gene id: 89673:BRF1
uniprot id: A0A6J2L748
names: Similarity
messages: Belongs to the TFIIB family.

89673:EPN2
gene id: 89673:EPN2
uniprot id: A0A6J2NE45
uniprot id: A0A6J2NJ76
uniprot id: A0A7E6ECU7
names: Similarity
messages: Belongs to the epsin family.

89673:PRAME
gene id: 89673:PRAME
uniprot id: A0A6J2N3Y4
names: Similarity
messages: Belongs to the PRAME family.

89673:LOC114500662
gene id: 89673:LOC114500662
uniprot id: A0A6J2M4P6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114500130
gene id: 89673:LOC114500130
uniprot id: A0A6J2M397
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TATDN2
gene id: 89673:TATDN2
uniprot id: A0A7E6E5Q7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

89673:KCNF1
gene id: 89673:KCNF1
uniprot id: A0A6J2LZG3
names: Subcellular Location Annotation
messages: Membrane

89673:CNIH2
gene id: 89673:CNIH2
uniprot id: A0A6J2LXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

89673:SDR9C7
gene id: 89673:SDR9C7
uniprot id: A0A6J2N4E3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:TEAD1
gene id: 89673:TEAD1
uniprot id: A0A6J2M0K2
uniprot id: A0A7E6E0C7
uniprot id: A0A7E6E0L0
uniprot id: A0A7E6E0W0
uniprot id: A0A7E6E0W6
uniprot id: A0A7E6E1K0
uniprot id: A0A7E6E1M1
names: Subcellular Location Annotation
messages: Nucleus

89673:MC1R
gene id: 89673:MC1R
uniprot id: A0A6J2KZ09
names: Subcellular Location Annotation
messages: Membrane

89673:ARHGEF18
gene id: 89673:ARHGEF18
uniprot id: A0A6J2MY66
uniprot id: A0A6J2N2T7
names: Subcellular Location Annotation
messages: Cytoplasm

89673:PLA2G2F
gene id: 89673:PLA2G2F
uniprot id: A0A7E6DRA9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

89673:LOC114502638
gene id: 89673:LOC114502638
uniprot id: A0A6J2M7Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

89673:LOC114506113
gene id: 89673:LOC114506113
uniprot id: A0A6J2MMW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:LOC114499220
gene id: 89673:LOC114499220
uniprot id: A0A6J2LVF9
names: Similarity
messages: Belongs to the PRORSD1 family.

89673:PAM
gene id: 89673:PAM
uniprot id: A0A6J2LCN0
uniprot id: A0A6J2LD15
uniprot id: A0A6J2LDW0
uniprot id: A0A6J2LE16
uniprot id: A0A6J2LF23
uniprot id: A0A6J2LIJ8
uniprot id: A0A6J2LIP2
uniprot id: A0A7E6DAX3
uniprot id: A0A7E6DB04
uniprot id: A0A7E6DBB5
uniprot id: A0A7E6DBC0
uniprot id: A0A7E6DC31
uniprot id: A0A7E6DDD0
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
messages: In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Membrane
messages: secretory vesicle membrane

89673:RAB14
gene id: 89673:RAB14
uniprot id: A0A6J2N6R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

89673:SLC6A15
gene id: 89673:SLC6A15
uniprot id: A0A6J2NE52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

89673:LOC114501399
gene id: 89673:LOC114501399
uniprot id: A0A6J2M5Y6
names: Similarity
messages: Belongs to the actin family.

89673:MVB12B
gene id: 89673:MVB12B
uniprot id: A0A6J2N9F7
uniprot id: A0A7E6DGE4
uniprot id: A0A7E6DGI0
uniprot id: A0A7E6DGM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

89673:HSP90B1
gene id: 89673:HSP90B1
uniprot id: A0A6J2N6M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

89673:GPR107
gene id: 89673:GPR107
uniprot id: A0A6J2M1R2
uniprot id: A0A7E6DGQ8
uniprot id: A0A7E6DGZ9
names: Subcellular Location Annotation
messages: Membrane

89673:PRIM1
gene id: 89673:PRIM1
uniprot id: A0A6J2N8Q3
uniprot id: A0A7E6D615
uniprot id: A0A7E6D6N2
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

89673:IRF5
gene id: 89673:IRF5
uniprot id: A0A6J2MPD2
uniprot id: A0A7E6CII2
uniprot id: A0A7E6CIX9
uniprot id: A0A7E6CKR4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:LOC114509102
gene id: 89673:LOC114509102
uniprot id: A0A6J2MS55
uniprot id: A0A6J2MTU6
uniprot id: A0A6J2MTU9
uniprot id: A0A6J2MTV0
uniprot id: A0A6J2MYE0
uniprot id: A0A6J2MYV2
uniprot id: A0A7E6CRY1
uniprot id: A0A7E6CSB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

89673:C8B
gene id: 89673:C8B
uniprot id: A0A6J2LT76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:DGCR6L
gene id: 89673:DGCR6L
uniprot id: A0A6J2MXI9
uniprot id: A0A7E6CU29
uniprot id: A0A7E6CUL7
uniprot id: A0A7E6CUT3
names: Similarity
messages: Belongs to the gonadal family.

89673:CEP57
gene id: 89673:CEP57
uniprot id: A0A6J2M298
names: Similarity
messages: Belongs to the translokin family.

89673:FAT2
gene id: 89673:FAT2
uniprot id: A0A6J2MUK8
uniprot id: A0A7E6CWT2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GLIS3
gene id: 89673:GLIS3
uniprot id: A0A6J2MX63
uniprot id: A0A7E6DEW9
uniprot id: A0A7E6DEZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

89673:SLC5A10
gene id: 89673:SLC5A10
uniprot id: A0A6J2NEP9
uniprot id: A0A6J2NF32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

89673:PWWP3A
gene id: 89673:PWWP3A
uniprot id: A0A6J2MCA6
uniprot id: A0A7E6E8M7
uniprot id: A0A7E6EAN8
names: Similarity
messages: Belongs to the PWWP3A family.

89673:AXL
gene id: 89673:AXL
uniprot id: A0A6J2MYL5
uniprot id: A0A6J2N4X6
uniprot id: A0A7E6CM14
uniprot id: A0A7E6CPA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

89673:F12
gene id: 89673:F12
uniprot id: A0A7E6CS73
uniprot id: A0A7E6CS76
uniprot id: A0A7E6CSW1
uniprot id: A0A7E6CUW2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:SERPINB5
gene id: 89673:SERPINB5
uniprot id: A0A6J2MRL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family. Ov-serpin subfamily.
messages: extracellular space

89673:CACNB3
gene id: 89673:CACNB3
uniprot id: A0A6J2N5Q5
uniprot id: A0A6J2N7H5
uniprot id: A0A7E6D6W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Cytoplasm

89673:ENTPD4
gene id: 89673:ENTPD4
uniprot id: A0A6J2MAY7
uniprot id: A0A6J2MBI6
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

89673:COQ4
gene id: 89673:COQ4
uniprot id: A0A6J2MHH8
uniprot id: A0A7E6DGU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

89673:POLR3B
gene id: 89673:POLR3B
uniprot id: A0A6J2NFI4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

89673:MYO10
gene id: 89673:MYO10
uniprot id: A0A6J2N2T4
uniprot id: A0A6J2N4J0
uniprot id: A0A7E6DAA5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:MVD
gene id: 89673:MVD
uniprot id: A0A6J2KQV4
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

89673:LOC114510355
gene id: 89673:LOC114510355
uniprot id: A0A6J2N3H3
uniprot id: A0A7E6CT45
uniprot id: A0A7E6CTD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ERAP2
gene id: 89673:ERAP2
uniprot id: A0A7E6DAZ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

89673:ELAVL4
gene id: 89673:ELAVL4
uniprot id: A0A7E6DRZ5
names: Similarity
messages: Belongs to the RRM elav family.

89673:WIF1
gene id: 89673:WIF1
uniprot id: A0A6J2NFR9
names: Caution
names: Function
messages: Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RPS7
gene id: 89673:RPS7
uniprot id: A0A6J2M1W4
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: Required for rRNA maturation.

89673:C1QA
gene id: 89673:C1QA
uniprot id: A0A6J2LMR8
names: Function
messages: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

89673:MINDY4
gene id: 89673:MINDY4
uniprot id: A0A6J2MNH0
uniprot id: A0A7E6CHP4
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

89673:GNG2
gene id: 89673:GNG2
uniprot id: A0A7E6CGC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:DPY19L4
gene id: 89673:DPY19L4
uniprot id: A0A6J2NHC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

89673:CPB1
gene id: 89673:CPB1
uniprot id: A0A6J2L045
names: Similarity
messages: Belongs to the peptidase M14 family.

89673:PFDN1
gene id: 89673:PFDN1
uniprot id: A0A6J2N2T5
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

89673:MRS2
gene id: 89673:MRS2
uniprot id: A0A6J2KYQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

89673:SLC44A1
gene id: 89673:SLC44A1
uniprot id: A0A6J2L566
uniprot id: A0A7E6DFR9
uniprot id: A0A7E6DFY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

89673:TMC4
gene id: 89673:TMC4
uniprot id: A0A6J2N1K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

89673:TIMM21
gene id: 89673:TIMM21
uniprot id: A0A6J2MR32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane
messages: Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.

89673:RSPO1
gene id: 89673:RSPO1
uniprot id: A0A6J2LUA0
names: Similarity
messages: Belongs to the R-spondin family.

89673:LOC114503547
gene id: 89673:LOC114503547
uniprot id: A0A6J2MFU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC39A11
gene id: 89673:SLC39A11
uniprot id: A0A6J2MEG8
uniprot id: A0A7E6ED57
uniprot id: A0A7E6EDC4
names: Subcellular Location Annotation
messages: Membrane

89673:KCNG2
gene id: 89673:KCNG2
uniprot id: A0A6J2MQ51
names: Subcellular Location Annotation
messages: Membrane

89673:CCNK
gene id: 89673:CCNK
uniprot id: A0A6J2L547
names: Similarity
messages: Belongs to the cyclin family.

89673:SNRPA
gene id: 89673:SNRPA
uniprot id: A0A6J2N2K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM U1 A/B'' family.
messages: Nucleus

89673:POGLUT3
gene id: 89673:POGLUT3
uniprot id: A0A6J2M410
names: Similarity
messages: Belongs to the KDELC family.

89673:VIPR1
gene id: 89673:VIPR1
uniprot id: A0A6J2M4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

89673:LOC114493019
gene id: 89673:LOC114493019
uniprot id: A0A6J2L8Y1
uniprot id: A0A7E6DFT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

89673:RABGGTA
gene id: 89673:RABGGTA
uniprot id: A0A6J2LAB3
uniprot id: A0A7E6E422
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.

89673:CTU2
gene id: 89673:CTU2
uniprot id: A0A6J2KU39
uniprot id: A0A7E6CMX8
uniprot id: A0A7E6CQB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTU2/NCS2 family.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

89673:MOV10
gene id: 89673:MOV10
uniprot id: A0A6J2KTV0
uniprot id: A0A7E6CYK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

89673:SETD7
gene id: 89673:SETD7
uniprot id: A0A6J2MBU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.
messages: Chromosome
messages: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
messages: Nucleus

89673:LOC114503645
gene id: 89673:LOC114503645
uniprot id: A0A6J2MCT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CALR
gene id: 89673:CALR
uniprot id: A0A6J2M8L3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen
messages: Monomer.

89673:WARS1
gene id: 89673:WARS1
uniprot id: A0A6J2L3G4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

89673:SGK3
gene id: 89673:SGK3
uniprot id: A0A6J2NBA8
uniprot id: A0A6J2NCZ5
uniprot id: A0A6J2NIQ3
uniprot id: A0A7E6E6Q1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

89673:NHP2
gene id: 89673:NHP2
uniprot id: A0A6J2MUY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

89673:GMFB
gene id: 89673:GMFB
uniprot id: A0A6J2L7M3
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

89673:LOC114509864
gene id: 89673:LOC114509864
uniprot id: A0A6J2N1V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:XPO7
gene id: 89673:XPO7
uniprot id: A0A7E6EAZ7
uniprot id: A0A7E6EC85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

89673:SCNN1G
gene id: 89673:SCNN1G
uniprot id: A0A6J2N5J6
names: Subcellular Location Annotation
messages: Membrane

89673:SERPINB2
gene id: 89673:SERPINB2
uniprot id: A0A6J2MS59
uniprot id: A0A7E6CGH6
names: Similarity
messages: Belongs to the serpin family.

89673:LOC114494199
gene id: 89673:LOC114494199
uniprot id: A0A7E6DN41
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

89673:RING1
gene id: 89673:RING1
uniprot id: A0A6J2LDG8
names: Function
names: Subcellular Location Annotation
messages: Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity.
messages: Nucleus speckle

89673:PSME1
gene id: 89673:PSME1
uniprot id: A0A6J2L914
names: Similarity
messages: Belongs to the PA28 family.

89673:BPIFC
gene id: 89673:BPIFC
uniprot id: A0A6J2N6E9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

89673:ZDHHC23
gene id: 89673:ZDHHC23
uniprot id: A0A6J2KXT6
uniprot id: A0A6J2L028
uniprot id: A0A6J2L3K0
uniprot id: A0A7E6D6T8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:CORO1C
gene id: 89673:CORO1C
uniprot id: A0A6J2MV11
uniprot id: A0A7E6CU66
names: Similarity
messages: Belongs to the WD repeat coronin family.

89673:LOC114509790
gene id: 89673:LOC114509790
uniprot id: A0A6J2MX15
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

89673:KRT13
gene id: 89673:KRT13
uniprot id: A0A6J2MAL7
names: Similarity
messages: Belongs to the intermediate filament family.

89673:TNRC6B
gene id: 89673:TNRC6B
uniprot id: A0A7E6D8F9
uniprot id: A0A7E6D8I4
uniprot id: A0A7E6D974
names: Similarity
messages: Belongs to the GW182 family.

89673:GLYCTK
gene id: 89673:GLYCTK
uniprot id: A0A6J2M5F3
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

89673:PTPA
gene id: 89673:PTPA
uniprot id: A0A6J2MZ88
uniprot id: A0A7E6DGY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:LOC114488218
gene id: 89673:LOC114488218
uniprot id: A0A6J2KR40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Golgi apparatus
messages: May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis.
messages: Nucleus
messages: cytoskeleton

89673:LOC114498764
gene id: 89673:LOC114498764
uniprot id: A0A7E6DYP0
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

89673:ST6GALNAC5
gene id: 89673:ST6GALNAC5
uniprot id: A0A6J2LSM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:FDPS
gene id: 89673:FDPS
uniprot id: A0A6J2KYR1
uniprot id: A0A7E6CX79
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

89673:LOC114497169
gene id: 89673:LOC114497169
uniprot id: A0A6J2LLC6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

89673:TPD52L1
gene id: 89673:TPD52L1
uniprot id: A0A6J2LD90
uniprot id: A0A6J2LFE7
uniprot id: A0A6J2LIW2
uniprot id: A0A6J2LIW6
uniprot id: A0A7E6DN09
uniprot id: A0A7E6DN34
uniprot id: A0A7E6DNI8
uniprot id: A0A7E6DNP1
names: Similarity
messages: Belongs to the TPD52 family.

89673:CPD
gene id: 89673:CPD
uniprot id: A0A6J2MDF9
names: Similarity
messages: Belongs to the peptidase M14 family.

89673:RMND1
gene id: 89673:RMND1
uniprot id: A0A6J2LFU9
names: Similarity
messages: Belongs to the RMD1/sif2 family.

89673:ANKRD34B
gene id: 89673:ANKRD34B
uniprot id: A0A6J2M5E2
names: Similarity
messages: Belongs to the ANKRD34 family.

89673:MDFIC
gene id: 89673:MDFIC
uniprot id: A0A6J2MP13
uniprot id: A0A7E6CIC8
uniprot id: A0A7E6CKG4
names: Similarity
messages: Belongs to the MDFI family.

89673:MMP20
gene id: 89673:MMP20
uniprot id: A0A6J2M1J1
names: Similarity
messages: Belongs to the peptidase M10A family.

89673:ITIH1
gene id: 89673:ITIH1
uniprot id: A0A6J2M7Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

89673:LOC114494303
gene id: 89673:LOC114494303
uniprot id: A0A7E6DK37
names: Similarity
messages: Belongs to the intermediate filament family.

89673:RPL13A
gene id: 89673:RPL13A
uniprot id: A0A6J2N763
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

89673:LOC114510051
gene id: 89673:LOC114510051
uniprot id: A0A6J2N2W7
names: Similarity
messages: Belongs to the TPPP family.

89673:LOC114495079
gene id: 89673:LOC114495079
uniprot id: A0A6J2LIX5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:NOTUM
gene id: 89673:NOTUM
uniprot id: A0A6J2MA35
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

89673:DSCC1
gene id: 89673:DSCC1
uniprot id: A0A6J2NHX7
names: Similarity
messages: Belongs to the DCC1 family.

89673:SELENOS
gene id: 89673:SELENOS
uniprot id: A0A6J2KVM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein S family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
messages: Membrane

89673:CHCHD4
gene id: 89673:CHCHD4
uniprot id: A0A6J2M3R0
uniprot id: A0A7E6E5J3
uniprot id: A0A7E6E5M8
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

89673:PKD1L3
gene id: 89673:PKD1L3
uniprot id: A0A6J2KR24
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:C8H19orf25
gene id: 89673:C8H19orf25
uniprot id: A0A6J2M9F4
names: Similarity
messages: Belongs to the UPF0449 family.

89673:AKR1D1
gene id: 89673:AKR1D1
uniprot id: A0A6J2MV97
uniprot id: A0A7E6CJ19
names: Similarity
messages: Belongs to the aldo/keto reductase family.

89673:GMPPA
gene id: 89673:GMPPA
uniprot id: A0A7E6DI07
uniprot id: A0A7E6DI34
uniprot id: A0A7E6DI89
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

89673:TNK2
gene id: 89673:TNK2
uniprot id: A0A6J2KZ43
uniprot id: A0A7E6D4D9
uniprot id: A0A7E6D4F4
uniprot id: A0A7E6D4H9
uniprot id: A0A7E6D4J1
uniprot id: A0A7E6D4K8
uniprot id: A0A7E6D4L5
uniprot id: A0A7E6D4M1
uniprot id: A0A7E6D528
uniprot id: A0A7E6D539
uniprot id: A0A7E6D549
uniprot id: A0A7E6D783
uniprot id: A0A7E6D795
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nucleus

89673:FGF11
gene id: 89673:FGF11
uniprot id: A0A6J2NEI9
uniprot id: A0A6J2NJP0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:LOC114500712
gene id: 89673:LOC114500712
uniprot id: A0A6J2M1X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ALG13
gene id: 89673:ALG13
uniprot id: A0A6J2MDH3
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

89673:APOA4
gene id: 89673:APOA4
uniprot id: A0A6J2LXT8
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

89673:FAM114A2
gene id: 89673:FAM114A2
uniprot id: A0A6J2N274
uniprot id: A0A7E6CTJ8
names: Similarity
messages: Belongs to the FAM114 family.

89673:SH3PXD2A
gene id: 89673:SH3PXD2A
uniprot id: A0A6J2LIV6
uniprot id: A0A6J2LL68
uniprot id: A0A6J2LNV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

89673:LOC114494161
gene id: 89673:LOC114494161
uniprot id: A0A6J2LGL7
uniprot id: A0A7E6DKW0
uniprot id: A0A7E6DKW3
uniprot id: A0A7E6DKW7
uniprot id: A0A7E6DLA3
uniprot id: A0A7E6DLL3
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:UXT
gene id: 89673:UXT
uniprot id: A0A6J2MKY8
names: Similarity
messages: Belongs to the UXT family.

89673:TET3
gene id: 89673:TET3
uniprot id: A0A6J2LWK4
uniprot id: A0A7E6DY00
uniprot id: A0A7E6DYV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

89673:SLC12A6
gene id: 89673:SLC12A6
uniprot id: A0A6J2KX87
uniprot id: A0A6J2L171
uniprot id: A0A6J2L322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

89673:TERF2
gene id: 89673:TERF2
uniprot id: A0A6J2NDH4
uniprot id: A0A6J2NF41
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus
messages: telomere

89673:BCL7C
gene id: 89673:BCL7C
uniprot id: A0A6J2N0A4
names: Similarity
messages: Belongs to the BCL7 family.

89673:SLC25A14
gene id: 89673:SLC25A14
uniprot id: A0A6J2MH60
uniprot id: A0A6J2MLG3
uniprot id: A0A7E6CYW5
uniprot id: A0A7E6CZQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:PKM
gene id: 89673:PKM
uniprot id: A0A6J2L1K5
uniprot id: A0A6J2L1L0
uniprot id: A0A6J2L3X0
uniprot id: A0A6J2L5X5
names: Similarity
messages: Belongs to the pyruvate kinase family.

89673:CHPT1
gene id: 89673:CHPT1
uniprot id: A0A6J2N7V5
uniprot id: A0A7E6D7W8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

89673:EDC3
gene id: 89673:EDC3
uniprot id: A0A6J2L947
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

89673:ZHX2
gene id: 89673:ZHX2
uniprot id: A0A6J2ND96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

89673:CMTM7
gene id: 89673:CMTM7
uniprot id: A0A6J2M4P4
names: Subcellular Location Annotation
messages: Membrane

89673:KCNJ12
gene id: 89673:KCNJ12
uniprot id: A0A6J2NEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ12 subfamily.
messages: Cell membrane
messages: Membrane

89673:GFOD2
gene id: 89673:GFOD2
uniprot id: A0A6J2KQV8
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

89673:SEPTIN7
gene id: 89673:SEPTIN7
uniprot id: A0A6J2MNP5
uniprot id: A0A6J2MNT2
uniprot id: A0A6J2MT29
uniprot id: A0A7E6CHL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium axoneme
messages: flagellum
messages: kinetochore
messages: spindle

89673:LOC114490192
gene id: 89673:LOC114490192
uniprot id: A0A6J2L2R3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MAP3K6
gene id: 89673:MAP3K6
uniprot id: A0A6J2LNG2
uniprot id: A0A6J2LTX1
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

89673:LOC114506244
gene id: 89673:LOC114506244
uniprot id: A0A6J2MHK6
uniprot id: A0A6J2MHL0
uniprot id: A0A6J2MJC6
uniprot id: A0A6J2MJQ1
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

89673:SLC1A6
gene id: 89673:SLC1A6
uniprot id: A0A6J2MB59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

89673:RO60
gene id: 89673:RO60
uniprot id: A0A6J2N588
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

89673:LOC114490177
gene id: 89673:LOC114490177
uniprot id: A0A6J2L2Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PFKFB1
gene id: 89673:PFKFB1
uniprot id: A0A6J2MGQ9
uniprot id: A0A7E6CZR6
uniprot id: A0A7E6D011
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

89673:YIPF7
gene id: 89673:YIPF7
uniprot id: A0A7E6DCL4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:GUF1
gene id: 89673:GUF1
uniprot id: A0A6J2LCD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

89673:JAG1
gene id: 89673:JAG1
uniprot id: A0A6J2MJ46
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

89673:SCN7A
gene id: 89673:SCN7A
uniprot id: A0A7E6DJJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

89673:DOCK9
gene id: 89673:DOCK9
uniprot id: A0A6J2MQY7
uniprot id: A0A6J2MQZ3
uniprot id: A0A6J2MSP7
uniprot id: A0A6J2MSQ1
uniprot id: A0A6J2MSR5
uniprot id: A0A6J2MX88
uniprot id: A0A6J2MXN0
uniprot id: A0A7E6CK43
uniprot id: A0A7E6CK48
uniprot id: A0A7E6CK52
uniprot id: A0A7E6CK60
uniprot id: A0A7E6CK64
uniprot id: A0A7E6CK65
uniprot id: A0A7E6CK69
uniprot id: A0A7E6CK70
uniprot id: A0A7E6CK74
uniprot id: A0A7E6CK81
uniprot id: A0A7E6CK84
uniprot id: A0A7E6CK91
uniprot id: A0A7E6CK96
uniprot id: A0A7E6CM74
uniprot id: A0A7E6CM79
uniprot id: A0A7E6CM84
names: Similarity
messages: Belongs to the DOCK family.

89673:INPP5A
gene id: 89673:INPP5A
uniprot id: A0A6J2LL75
uniprot id: A0A7E6DVU7
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

89673:LOC114494508
gene id: 89673:LOC114494508
uniprot id: A0A7E6DHJ9
uniprot id: A0A7E6DHP3
names: Subcellular Location Annotation
messages: Nucleus

89673:ADAM7
gene id: 89673:ADAM7
uniprot id: A0A6J2MD02
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:HOXC12
gene id: 89673:HOXC12
uniprot id: A0A6J2N904
names: Subcellular Location Annotation
messages: Nucleus

89673:HOXA5
gene id: 89673:HOXA5
uniprot id: A0A7E6CHK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:CCN5
gene id: 89673:CCN5
uniprot id: A0A6J2MSB0
names: Similarity
messages: Belongs to the CCN family.

89673:OXA1L
gene id: 89673:OXA1L
uniprot id: A0A6J2LB02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

89673:LOC114506081
gene id: 89673:LOC114506081
uniprot id: A0A6J2MN98
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

89673:CENPO
gene id: 89673:CENPO
uniprot id: A0A6J2M2Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

89673:TUBB4A
gene id: 89673:TUBB4A
uniprot id: A0A6J2M8Q6
uniprot id: A0A7E6E9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

89673:KATNAL2
gene id: 89673:KATNAL2
uniprot id: A0A6J2MJH9
uniprot id: A0A7E6CGN4
uniprot id: A0A7E6CGS1
uniprot id: A0A7E6CIV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

89673:ZBED6
gene id: 89673:ZBED6
uniprot id: A0A6J2N4Q8
names: Subcellular Location Annotation
messages: Nucleus

89673:CDH22
gene id: 89673:CDH22
uniprot id: A0A6J2MLY2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:FAM187A
gene id: 89673:FAM187A
uniprot id: A0A6J2MGQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

89673:YIPF5
gene id: 89673:YIPF5
uniprot id: A0A6J2MWW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

89673:KCNT2
gene id: 89673:KCNT2
uniprot id: A0A6J2N599
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:FAT3
gene id: 89673:FAT3
uniprot id: A0A6J2LYI1
uniprot id: A0A7E6DZG0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:NCAPD2
gene id: 89673:NCAPD2
uniprot id: A0A6J2NC16
uniprot id: A0A7E6D1T4
uniprot id: A0A7E6D1W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

89673:PRKD1
gene id: 89673:PRKD1
uniprot id: A0A6J2L4X2
uniprot id: A0A6J2L8H6
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

89673:SOX14
gene id: 89673:SOX14
uniprot id: A0A6J2M5I7
names: Subcellular Location Annotation
messages: Nucleus

89673:TSPAN18
gene id: 89673:TSPAN18
uniprot id: A0A6J2M2Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:LOC114499825
gene id: 89673:LOC114499825
uniprot id: A0A6J2LWK3
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

89673:PLA1A
gene id: 89673:PLA1A
uniprot id: A0A6J2L456
uniprot id: A0A7E6D4R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

89673:E2F8
gene id: 89673:E2F8
uniprot id: A0A6J2M0P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

89673:DCTN6
gene id: 89673:DCTN6
uniprot id: A0A6J2MSM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: cytoskeleton

89673:ATM
gene id: 89673:ATM
uniprot id: A0A6J2LRX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Cytoplasmic vesicle
messages: Nucleus
messages: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9, UBQLN4 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response. Phosphorylates ERCC6 which is essential for its chromatin remodeling activity at DNA double-strand breaks.

89673:IFITM5
gene id: 89673:IFITM5
uniprot id: A0A6J2M1S2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:NFIA
gene id: 89673:NFIA
uniprot id: A0A7E6DW85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

89673:NID2
gene id: 89673:NID2
uniprot id: A0A7E6CI68
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

89673:MAST1
gene id: 89673:MAST1
uniprot id: A0A6J2M7V6
uniprot id: A0A6J2MBA4
uniprot id: A0A7E6E9H7
uniprot id: A0A7E6EAB6
uniprot id: A0A7E6EAJ1
uniprot id: A0A7E6EB63
uniprot id: A0A7E6EBJ0
uniprot id: A0A7E6EBK0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

89673:LOC114511703
gene id: 89673:LOC114511703
uniprot id: A0A6J2N392
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

89673:SOGA3
gene id: 89673:SOGA3
uniprot id: A0A6J2LD35
uniprot id: A0A7E6DN33
uniprot id: A0A7E6DP19
names: Similarity
messages: Belongs to the SOGA family.

89673:LOC114497216
gene id: 89673:LOC114497216
uniprot id: A0A6J2LNW5
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:HTR1B
gene id: 89673:HTR1B
uniprot id: A0A6J2LIM7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
messages: Homodimer. Heterodimer with HTR1D.
messages: Ligands are bound in a hydrophobic pocket formed by the transmembrane helices.
messages: Membrane
messages: Palmitoylated.
messages: Phosphorylated.

89673:ADRB3
gene id: 89673:ADRB3
uniprot id: A0A6J2MXJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
messages: Cell membrane
messages: Interacts with ARRDC3.
messages: Membrane

89673:TRADD
gene id: 89673:TRADD
uniprot id: A0A7E6CLS0
uniprot id: A0A7E6CLY4
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

89673:IARS1
gene id: 89673:IARS1
uniprot id: A0A6J2N6G7
uniprot id: A0A6J2NBX5
uniprot id: A0A7E6D4V8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

89673:SLC29A2
gene id: 89673:SLC29A2
uniprot id: A0A6J2M1K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

89673:HPGD
gene id: 89673:HPGD
uniprot id: A0A6J2MHJ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:HCRTR2
gene id: 89673:HCRTR2
uniprot id: A0A6J2LJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:BANF2
gene id: 89673:BANF2
uniprot id: A0A6J2MN30
names: Subcellular Location Annotation
messages: Nucleus

89673:XRCC5
gene id: 89673:XRCC5
uniprot id: A0A6J2LFG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus

89673:HAL
gene id: 89673:HAL
uniprot id: A0A6J2N9R5
uniprot id: A0A7E6D8J1
names: Similarity
messages: Belongs to the PAL/histidase family.

89673:TTC38
gene id: 89673:TTC38
uniprot id: A0A6J2N972
names: Similarity
messages: Belongs to the TTC38 family.

89673:PNLDC1
gene id: 89673:PNLDC1
uniprot id: A0A6J2LK72
uniprot id: A0A7E6DNV0
names: Similarity
messages: Belongs to the CAF1 family.

89673:LOC114500418
gene id: 89673:LOC114500418
uniprot id: A0A6J2M4C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HSPD1
gene id: 89673:HSPD1
uniprot id: A0A6J2LFB1
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

89673:TFAP2C
gene id: 89673:TFAP2C
uniprot id: A0A6J2MR63
uniprot id: A0A7E6CFY9
uniprot id: A0A7E6CG46
names: Similarity
messages: Belongs to the AP-2 family.

89673:CACNB2
gene id: 89673:CACNB2
uniprot id: A0A6J2L215
uniprot id: A0A6J2L220
uniprot id: A0A6J2L2Q8
uniprot id: A0A6J2L4B9
uniprot id: A0A6J2L4C4
uniprot id: A0A6J2L7Q7
uniprot id: A0A6J2L7R2
uniprot id: A0A7E6DK98
uniprot id: A0A7E6DKA6
uniprot id: A0A7E6DKD6
uniprot id: A0A7E6DKL9
uniprot id: A0A7E6DKP5
uniprot id: A0A7E6DKY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
messages: sarcolemma

89673:CPQ
gene id: 89673:CPQ
uniprot id: A0A6J2NIR4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome
messages: Secreted

89673:U2AF2
gene id: 89673:U2AF2
uniprot id: A0A6J2N065
uniprot id: A0A6J2N5M3
uniprot id: A0A7E6CQF5
uniprot id: A0A7E6CQU6
uniprot id: A0A7E6CQV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

89673:LOC114507846
gene id: 89673:LOC114507846
uniprot id: A0A6J2MUN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114506163
gene id: 89673:LOC114506163
uniprot id: A0A7E6CGL9
names: Subcellular Location Annotation
messages: Nucleus

89673:CACNA1E
gene id: 89673:CACNA1E
uniprot id: A0A7E6CY79
uniprot id: A0A7E6CYM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.

89673:LOC114511244
gene id: 89673:LOC114511244
uniprot id: A0A7E6CTN2
names: Subcellular Location Annotation
messages: Nucleus

89673:DHTKD1
gene id: 89673:DHTKD1
uniprot id: A0A6J2LCE8
uniprot id: A0A7E6DMN8
uniprot id: A0A7E6DMP5
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

89673:TRAPPC6A
gene id: 89673:TRAPPC6A
uniprot id: A0A6J2N6J5
uniprot id: A0A7E6CQ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

89673:DTD2
gene id: 89673:DTD2
uniprot id: A0A6J2L6K8
names: Similarity
messages: Belongs to the DTD family.

89673:IL15
gene id: 89673:IL15
uniprot id: A0A6J2MG25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

89673:HOXC5
gene id: 89673:HOXC5
uniprot id: A0A6J2N846
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:DNM1
gene id: 89673:DNM1
uniprot id: A0A6J2LG28
uniprot id: A0A6J2LG46
uniprot id: A0A6J2LIL8
uniprot id: A0A6J2LIM2
uniprot id: A0A6J2LIM6
uniprot id: A0A6J2LJG3
uniprot id: A0A7E6DGJ4
uniprot id: A0A7E6DGN5
uniprot id: A0A7E6DGP7
uniprot id: A0A7E6DGQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: cytoskeleton

89673:LOC114508182
gene id: 89673:LOC114508182
uniprot id: A0A6J2MR67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:TRAM1
gene id: 89673:TRAM1
uniprot id: A0A6J2NHQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

89673:FAM83A
gene id: 89673:FAM83A
uniprot id: A0A6J2NIX4
names: Similarity
messages: Belongs to the FAM83 family.

89673:BCO1
gene id: 89673:BCO1
uniprot id: A0A6J2KRQ1
uniprot id: A0A7E6CMP0
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

89673:ART3
gene id: 89673:ART3
uniprot id: A0A6J2LAQ3
uniprot id: A0A7E6DH05
uniprot id: A0A7E6DH08
uniprot id: A0A7E6DH24
uniprot id: A0A7E6DH42
uniprot id: A0A7E6DH46
uniprot id: A0A7E6DH53
uniprot id: A0A7E6DH59
uniprot id: A0A7E6DHA1
uniprot id: A0A7E6DHA7
uniprot id: A0A7E6DHC2
uniprot id: A0A7E6DHD9
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

89673:METRNL
gene id: 89673:METRNL
uniprot id: A0A6J2MDB7
uniprot id: A0A7E6EF21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the meteorin family.
messages: Secreted

89673:TREX2
gene id: 89673:TREX2
uniprot id: A0A6J2MJ25
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

89673:LOC114512650
gene id: 89673:LOC114512650
uniprot id: A0A6J2NAZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:ATP6V1G3
gene id: 89673:ATP6V1G3
uniprot id: A0A6J2N401
uniprot id: A0A7E6CYL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

89673:MYO9A
gene id: 89673:MYO9A
uniprot id: A0A6J2L8I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Cytoplasm
messages: Membrane
messages: Synapse
messages: growth cone

89673:GRIK4
gene id: 89673:GRIK4
uniprot id: A0A6J2MV81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

89673:DDC
gene id: 89673:DDC
uniprot id: A0A7E6CH22
uniprot id: A0A7E6CJ58
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

89673:CDK2AP2
gene id: 89673:CDK2AP2
uniprot id: A0A6J2LYW9
uniprot id: A0A6J2M4F9
names: Similarity
messages: Belongs to the CDK2AP family.

89673:SPESP1
gene id: 89673:SPESP1
uniprot id: A0A6J2LD95
names: Function
names: Similarity
messages: Belongs to the SPESP1 family.
messages: Involved in fertilization ability of sperm.

89673:THYN1
gene id: 89673:THYN1
uniprot id: A0A6J2MW45
uniprot id: A0A7E6CWM6
names: Function
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

89673:LOC114498715
gene id: 89673:LOC114498715
uniprot id: A0A7E6E3A2
names: Similarity
messages: Belongs to the NipSnap family.

89673:NECAP2
gene id: 89673:NECAP2
uniprot id: A0A6J2LMH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

89673:LOC114502299
gene id: 89673:LOC114502299
uniprot id: A0A6J2M9F1
names: Subcellular Location Annotation
messages: Membrane

89673:ACOT13
gene id: 89673:ACOT13
uniprot id: A0A6J2KVI3
names: Similarity
messages: Belongs to the thioesterase PaaI family.

89673:HOXC6
gene id: 89673:HOXC6
uniprot id: A0A6J2N9V3
uniprot id: A0A7E6D6D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:LOC118501442
gene id: 89673:LOC118501442
uniprot id: A0A7E6E3C2
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

89673:LOC114490014
gene id: 89673:LOC114490014
uniprot id: A0A6J2L074
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

89673:LOC114496927
gene id: 89673:LOC114496927
uniprot id: A0A7E6DVW7
names: Similarity
messages: Belongs to the amidase family.

89673:LOC114515185
gene id: 89673:LOC114515185
uniprot id: A0A6J2NCS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

89673:ATP6V1G1
gene id: 89673:ATP6V1G1
uniprot id: A0A6J2LW69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

89673:WDR35
gene id: 89673:WDR35
uniprot id: A0A6J2LVS0
uniprot id: A0A6J2LZM7
names: Function
names: Subcellular Location Annotation
messages: As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking.
messages: centrosome
messages: cilium basal body

89673:UNC93A
gene id: 89673:UNC93A
uniprot id: A0A6J2KX90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

89673:SH3BP5
gene id: 89673:SH3BP5
uniprot id: A0A6J2M5H1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

89673:LOC114497336
gene id: 89673:LOC114497336
uniprot id: A0A7E6DSE9
uniprot id: A0A7E6DTG2
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:ATPAF2
gene id: 89673:ATPAF2
uniprot id: A0A6J2NEJ2
uniprot id: A0A6J2NJI2
uniprot id: A0A7E6EBS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

89673:CSTF2T
gene id: 89673:CSTF2T
uniprot id: A0A6J2LI54
uniprot id: A0A7E6DW94
uniprot id: A0A7E6DXH9
names: Subcellular Location Annotation
messages: Nucleus

89673:CRYBB1
gene id: 89673:CRYBB1
uniprot id: A0A6J2N197
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

89673:TLE5
gene id: 89673:TLE5
uniprot id: A0A6J2MIR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

89673:NDC80
gene id: 89673:NDC80
uniprot id: A0A6J2MM63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

89673:LOC114500110
gene id: 89673:LOC114500110
uniprot id: A0A6J2M368
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TNN
gene id: 89673:TNN
uniprot id: A0A6J2N2Y6
uniprot id: A0A7E6CVR9
uniprot id: A0A7E6CVW4
uniprot id: A0A7E6CYI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

89673:CHST10
gene id: 89673:CHST10
uniprot id: A0A6J2LZQ0
uniprot id: A0A6J2M2S3
uniprot id: A0A6J2M373
uniprot id: A0A7E6DZM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:KIFC1
gene id: 89673:KIFC1
uniprot id: A0A7E6DL42
uniprot id: A0A7E6DLH7
uniprot id: A0A7E6DLJ9
uniprot id: A0A7E6DLV0
uniprot id: A0A7E6DLV6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:NSUN3
gene id: 89673:NSUN3
uniprot id: A0A6J2L3C3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

89673:WRNIP1
gene id: 89673:WRNIP1
uniprot id: A0A6J2LJ55
uniprot id: A0A6J2LKC2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

89673:LOC114500360
gene id: 89673:LOC114500360
uniprot id: A0A6J2M3M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CAPN1
gene id: 89673:CAPN1
uniprot id: A0A6J2LWX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C2 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

89673:YWHAZ
gene id: 89673:YWHAZ
uniprot id: A0A6J2NBP1
names: Similarity
messages: Belongs to the 14-3-3 family.

89673:RPS2
gene id: 89673:RPS2
uniprot id: A0A6J2LYY6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.

89673:AIG1
gene id: 89673:AIG1
uniprot id: A0A6J2LK04
uniprot id: A0A7E6DNG2
uniprot id: A0A7E6DNG4
uniprot id: A0A7E6DNI6
uniprot id: A0A7E6DNI9
uniprot id: A0A7E6DNY2
uniprot id: A0A7E6DNY7
uniprot id: A0A7E6DP54
uniprot id: A0A7E6DP58
uniprot id: A0A7E6DPF8
uniprot id: A0A7E6DPG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

89673:VAMP7
gene id: 89673:VAMP7
uniprot id: A0A6J2MED7
uniprot id: A0A7E6D3T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

89673:FAM126B
gene id: 89673:FAM126B
uniprot id: A0A6J2LM50
uniprot id: A0A7E6DIU5
uniprot id: A0A7E6DJ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

89673:LOC114510801
gene id: 89673:LOC114510801
uniprot id: A0A6J2N552
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PHYKPL
gene id: 89673:PHYKPL
uniprot id: A0A6J2N3H8
uniprot id: A0A7E6CSE1
uniprot id: A0A7E6CSV0
uniprot id: A0A7E6CV42
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

89673:TPRG1
gene id: 89673:TPRG1
uniprot id: A0A6J2L3S5
names: Similarity
messages: Belongs to the TPRG1 family.

89673:LOC114503330
gene id: 89673:LOC114503330
uniprot id: A0A7E6D9E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:LOC114505595
gene id: 89673:LOC114505595
uniprot id: A0A6J2MMU3
names: Similarity
messages: Belongs to the SPT20 family.

89673:SLC30A4
gene id: 89673:SLC30A4
uniprot id: A0A6J2L787
uniprot id: A0A7E6EB65
uniprot id: A0A7E6ECQ7
uniprot id: A0A7E6ECR4
uniprot id: A0A7E6ED40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

89673:UBA3
gene id: 89673:UBA3
uniprot id: A0A6J2M6T9
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

89673:CHRNB2
gene id: 89673:CHRNB2
uniprot id: A0A6J2KTZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:PKIA
gene id: 89673:PKIA
uniprot id: A0A6J2M5S6
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

89673:FGF1
gene id: 89673:FGF1
uniprot id: A0A6J2MZ22
uniprot id: A0A7E6CWZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

89673:LOC118500231
gene id: 89673:LOC118500231
uniprot id: A0A7E6DMM7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CPM
gene id: 89673:CPM
uniprot id: A0A6J2NBU1
names: Similarity
messages: Belongs to the peptidase M14 family.

89673:JAK1
gene id: 89673:JAK1
uniprot id: A0A6J2LSK1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

89673:METTL14
gene id: 89673:METTL14
uniprot id: A0A6J2M914
names: Similarity
messages: Belongs to the MT-A70-like family.

89673:PLD5
gene id: 89673:PLD5
uniprot id: A0A6J2NA19
uniprot id: A0A7E6CYG6
uniprot id: A0A7E6CYL2
uniprot id: A0A7E6D136
names: Similarity
messages: Belongs to the phospholipase D family.

89673:LOC114492564
gene id: 89673:LOC114492564
uniprot id: A0A6J2L9L3
uniprot id: A0A7E6DEK3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:DYRK2
gene id: 89673:DYRK2
uniprot id: A0A6J2NFU9
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

89673:LOC114491849
gene id: 89673:LOC114491849
uniprot id: A0A7E6D9Y7
names: Subcellular Location Annotation
messages: Nucleus

89673:SEPTIN11
gene id: 89673:SEPTIN11
uniprot id: A0A6J2L7K5
uniprot id: A0A7E6DHC7
uniprot id: A0A7E6DHF3
uniprot id: A0A7E6DHF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

89673:LOC114508026
gene id: 89673:LOC114508026
uniprot id: A0A6J2MVD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MAPK10
gene id: 89673:MAPK10
uniprot id: A0A6J2L478
uniprot id: A0A6J2L4V3
uniprot id: A0A6J2L4V8
uniprot id: A0A6J2L8U5
uniprot id: A0A6J2L8V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

89673:LOC118497253
gene id: 89673:LOC118497253
uniprot id: A0A7E6CJE0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:RORA
gene id: 89673:RORA
uniprot id: A0A6J2L8Z2
uniprot id: A0A6J2L9E6
uniprot id: A0A6J2LEL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

89673:MESD
gene id: 89673:MESD
uniprot id: A0A6J2KVC9
uniprot id: A0A7E6CSJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

89673:LOC114511214
gene id: 89673:LOC114511214
uniprot id: A0A6J2N665
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3. May form a heterodimer with CTU2/NCS2.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

89673:NAA35
gene id: 89673:NAA35
uniprot id: A0A6J2L865
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

89673:GAA
gene id: 89673:GAA
uniprot id: A0A6J2MCC3
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RPS16
gene id: 89673:RPS16
uniprot id: A0A6J2MYU0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

89673:TOB1
gene id: 89673:TOB1
uniprot id: A0A6J2MAZ7
names: Similarity
messages: Belongs to the BTG family.

89673:SELENOF
gene id: 89673:SELENOF
uniprot id: A0A6J2LSU6
names: Similarity
messages: Belongs to the selenoprotein M/F family.

89673:PROC
gene id: 89673:PROC
uniprot id: A0A6J2LJ52
uniprot id: A0A7E6DKH2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:LOC114510564
gene id: 89673:LOC114510564
uniprot id: A0A7E6CNA3
names: Subcellular Location Annotation
messages: Membrane

89673:BTF3
gene id: 89673:BTF3
uniprot id: A0A6J2M1C2
uniprot id: A0A6J2M3K1
names: Similarity
messages: Belongs to the NAC-beta family.

89673:RPRD1B
gene id: 89673:RPRD1B
uniprot id: A0A6J2MK85
uniprot id: A0A7E6CFF4
uniprot id: A0A7E6CHK8
names: Function
names: Similarity
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.

89673:GCH1
gene id: 89673:GCH1
uniprot id: A0A6J2LBW3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

89673:MXRA8
gene id: 89673:MXRA8
uniprot id: A0A6J2LLV6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:CAMK1D
gene id: 89673:CAMK1D
uniprot id: A0A6J2L8Z8
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:FAM133B
gene id: 89673:FAM133B
uniprot id: A0A6J2MMF0
names: Similarity
messages: Belongs to the FAM133 family.

89673:KCNS3
gene id: 89673:KCNS3
uniprot id: A0A6J2LS18
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:PRR15L
gene id: 89673:PRR15L
uniprot id: A0A6J2MEC5
names: Similarity
messages: Belongs to the PRR15 family.

89673:MYF5
gene id: 89673:MYF5
uniprot id: A0A6J2NA06
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

89673:LOC114515347
gene id: 89673:LOC114515347
uniprot id: A0A7E6EBV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NLRP family.
messages: Inflammasome

89673:NAXD
gene id: 89673:NAXD
uniprot id: A0A6J2MSQ5
uniprot id: A0A6J2MXN9
uniprot id: A0A7E6CKA8
uniprot id: A0A7E6CKC4
uniprot id: A0A7E6CME7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Mitochondrion

89673:DDX47
gene id: 89673:DDX47
uniprot id: A0A6J2NA45
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

89673:C4H6orf58
gene id: 89673:C4H6orf58
uniprot id: A0A6J2LF60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

89673:C3H16orf71
gene id: 89673:C3H16orf71
uniprot id: A0A6J2M6C9
uniprot id: A0A7E6DBV4
uniprot id: A0A7E6DBV8
uniprot id: A0A7E6DC44
uniprot id: A0A7E6DCH7
uniprot id: A0A7E6DD12
uniprot id: A0A7E6DDL1
uniprot id: A0A7E6DDL2
names: Function
messages: In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme. Interacts with outer dynein arm (ODA) subunits.

89673:SFRP4
gene id: 89673:SFRP4
uniprot id: A0A6J2MUJ5
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ELF2
gene id: 89673:ELF2
uniprot id: A0A6J2MC43
uniprot id: A0A6J2MI48
uniprot id: A0A7E6E7Z9
uniprot id: A0A7E6E8V3
uniprot id: A0A7E6E9V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:LOC114505342
gene id: 89673:LOC114505342
uniprot id: A0A7E6D192
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

89673:PHOX2A
gene id: 89673:PHOX2A
uniprot id: A0A6J2LZY5
names: Subcellular Location Annotation
messages: Nucleus

89673:VPS29
gene id: 89673:VPS29
uniprot id: A0A6J2MVY9
uniprot id: A0A6J2MXK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

89673:ASIC5
gene id: 89673:ASIC5
uniprot id: A0A7E6EHC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

89673:LOC114512336
gene id: 89673:LOC114512336
uniprot id: A0A6J2N5B0
names: Similarity
messages: Belongs to the peptidase C2 family.

89673:PELI1
gene id: 89673:PELI1
uniprot id: A0A6J2LT26
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

89673:INSIG1
gene id: 89673:INSIG1
uniprot id: A0A6J2MUG2
uniprot id: A0A7E6CL77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

89673:SENP5
gene id: 89673:SENP5
uniprot id: A0A6J2L064
uniprot id: A0A6J2L2H0
uniprot id: A0A6J2L4H0
uniprot id: A0A7E6D4L0
uniprot id: A0A7E6D4P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

89673:CCDC39
gene id: 89673:CCDC39
uniprot id: A0A6J2L0A6
uniprot id: A0A7E6D327
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC39 family.
messages: cilium axoneme

89673:ADGRG3
gene id: 89673:ADGRG3
uniprot id: A0A6J2KTA0
names: Subcellular Location Annotation
messages: Membrane

89673:IL6
gene id: 89673:IL6
uniprot id: A0A7E6CHJ1
uniprot id: A0A7E6CJI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Component of a hexamer of two molecules each of IL6, IL6R and IL6ST; first binds to IL6R to associate with the signaling subunit IL6ST. Interacts with IL6R (via the N-terminal ectodomain); this interaction may be affected by IL6R-binding with SORL1, hence decreasing IL6 cis signaling. Interacts with SORL1 (via the N-terminal ectodomain); this interaction leads to IL6 internalization and lysosomal degradation. May form a trimeric complex with the soluble SORL1 ectodomain and soluble IL6R receptor; this interaction might stabilize circulating IL6, hence promoting IL6 trans signaling.
messages: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
messages: IL6 is a potent inducer of the acute phase response. Rapid production of IL6 contributes to host defense during infection and tissue injury, but excessive IL6 synthesis is involved in disease pathology. In the innate immune response, is synthesized by myeloid cells, such as macrophages and dendritic cells, upon recognition of pathogens through toll-like receptors (TLRs) at the site of infection or tissue injury (By similarity). In the adaptive immune response, is required for the differentiation of B cells into immunoglobulin-secreting cells. Plays a major role in the differentiation of CD4(+) T cell subsets. Essential factor for the development of T follicular helper (Tfh) cells that are required for the induction of germinal-center formation. Required to drive naive CD4(+) T cells to the Th17 lineage. Also required for proliferation of myeloma cells and the survival of plasmablast cells.
messages: Secreted

89673:ODF2L
gene id: 89673:ODF2L
uniprot id: A0A7E6DSU0
uniprot id: A0A7E6DTF2
uniprot id: A0A7E6DTF7
uniprot id: A0A7E6DTL4
uniprot id: A0A7E6DU04
uniprot id: A0A7E6DU09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

89673:TMEM116
gene id: 89673:TMEM116
uniprot id: A0A6J2MWJ8
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114499950
gene id: 89673:LOC114499950
uniprot id: A0A6J2LX51
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

89673:RHPN2
gene id: 89673:RHPN2
uniprot id: A0A6J2MYH9
names: Similarity
messages: Belongs to the RHPN family.

89673:MYD88
gene id: 89673:MYD88
uniprot id: A0A6J2M3C2
uniprot id: A0A6J2M7J6
uniprot id: A0A7E6E5Z7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm
messages: Homodimer. Also forms heterodimers with TIRAP. Binds to TLR2, TLR4, IRAK1, IRAK2 and IRAK4 via their respective TIR domains.

89673:GBF1
gene id: 89673:GBF1
uniprot id: A0A6J2LI37
uniprot id: A0A6J2LJD1
uniprot id: A0A6J2LJD6
uniprot id: A0A6J2LKG0
uniprot id: A0A6J2LN13
uniprot id: A0A6J2LNR4
uniprot id: A0A7E6DV41
uniprot id: A0A7E6DV47
uniprot id: A0A7E6DV55
uniprot id: A0A7E6DV97
uniprot id: A0A7E6DVQ9
uniprot id: A0A7E6DW27
uniprot id: A0A7E6DW34
uniprot id: A0A7E6DWI4
names: Subcellular Location Annotation
messages: Golgi apparatus

89673:NIPAL1
gene id: 89673:NIPAL1
uniprot id: A0A6J2L6W2
uniprot id: A0A7E6D9V0
uniprot id: A0A7E6DCV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

89673:PPP6C
gene id: 89673:PPP6C
uniprot id: A0A6J2N8U6
uniprot id: A0A7E6DGG4
uniprot id: A0A7E6DGK5
uniprot id: A0A7E6DGM1
names: Similarity
messages: Belongs to the PPP phosphatase family.

89673:ISX
gene id: 89673:ISX
uniprot id: A0A6J2NAZ8
names: Subcellular Location Annotation
messages: Nucleus

89673:EXOC2
gene id: 89673:EXOC2
uniprot id: A0A6J2LI13
uniprot id: A0A7E6DU36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

89673:CHRNB1
gene id: 89673:CHRNB1
uniprot id: A0A7E6EBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:LOC114499033
gene id: 89673:LOC114499033
uniprot id: A0A6J2LUT5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:JPH1
gene id: 89673:JPH1
uniprot id: A0A7E6E6A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

89673:PPP1R12A
gene id: 89673:PPP1R12A
uniprot id: A0A6J2NE83
uniprot id: A0A6J2NEV9
uniprot id: A0A7E6D5L2
uniprot id: A0A7E6D5M9
uniprot id: A0A7E6D675
uniprot id: A0A7E6D8D3
names: Subcellular Location Annotation
names: Subunit
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.
messages: stress fiber

89673:LOC114499755
gene id: 89673:LOC114499755
uniprot id: A0A6J2M1A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ESRP1
gene id: 89673:ESRP1
uniprot id: A0A6J2NBF7
uniprot id: A0A6J2NDI0
uniprot id: A0A6J2NI96
uniprot id: A0A6J2NIU5
uniprot id: A0A7E6E6D9
uniprot id: A0A7E6E836
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESRP family.
messages: Nucleus

89673:ELOVL5
gene id: 89673:ELOVL5
uniprot id: A0A6J2LC29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: dendrite

89673:ILDR2
gene id: 89673:ILDR2
uniprot id: A0A7E6CVW1
uniprot id: A0A7E6CWC7
uniprot id: A0A7E6CYL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

89673:RIDA
gene id: 89673:RIDA
uniprot id: A0A6J2NI65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.
messages: Peroxisome

89673:MDM2
gene id: 89673:MDM2
uniprot id: A0A6J2N8H1
uniprot id: A0A7E6D5T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

89673:PNPO
gene id: 89673:PNPO
uniprot id: A0A6J2MD48
uniprot id: A0A7E6EFA9
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

89673:HK1
gene id: 89673:HK1
uniprot id: A0A6J2LIS2
uniprot id: A0A7E6DU69
uniprot id: A0A7E6DV45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

89673:ADHFE1
gene id: 89673:ADHFE1
uniprot id: A0A6J2NCT0
uniprot id: A0A7E6E6P3
uniprot id: A0A7E6E7T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

89673:HIP1
gene id: 89673:HIP1
uniprot id: A0A6J2L8S2
uniprot id: A0A6J2LBK4
uniprot id: A0A7E6DBF1
uniprot id: A0A7E6DBZ5
names: Similarity
messages: Belongs to the SLA2 family.

89673:HAPLN2
gene id: 89673:HAPLN2
uniprot id: A0A6J2KZH8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:PAICS
gene id: 89673:PAICS
uniprot id: A0A6J2LAX2
names: Similarity
names: Subunit
messages: Homooctamer.
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
messages: In the N-terminal section; belongs to the SAICAR synthetase family.

89673:HAP1
gene id: 89673:HAP1
uniprot id: A0A6J2M8B2
names: Subcellular Location Annotation
messages: Early endosome
messages: Mitochondrion

89673:RAB3GAP1
gene id: 89673:RAB3GAP1
uniprot id: A0A6J2LAF4
uniprot id: A0A6J2LFJ4
uniprot id: A0A7E6DKD3
uniprot id: A0A7E6DKN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm

89673:MPPE1
gene id: 89673:MPPE1
uniprot id: A0A6J2MRF2
uniprot id: A0A7E6CDZ8
uniprot id: A0A7E6CE04
uniprot id: A0A7E6CE65
uniprot id: A0A7E6CEQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallophosphoesterase superfamily. MPPE1 family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Interacts with GPI-anchor proteins. Interacts with TMED10.
messages: Membrane
messages: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
messages: cis-Golgi network membrane

89673:LOC114490099
gene id: 89673:LOC114490099
uniprot id: A0A6J2KYW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

89673:GRWD1
gene id: 89673:GRWD1
uniprot id: A0A6J2N0R9
names: Subcellular Location Annotation
messages: Nucleus

89673:DTNB
gene id: 89673:DTNB
uniprot id: A0A6J2LXT5
uniprot id: A0A6J2LYX2
uniprot id: A0A6J2LYX7
uniprot id: A0A6J2M2V4
uniprot id: A0A7E6DY10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

89673:LOC114511669
gene id: 89673:LOC114511669
uniprot id: A0A6J2N7N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:KATNAL1
gene id: 89673:KATNAL1
uniprot id: A0A6J2NDA0
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and DCAF1 proteins (EDVP complex). Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42. Interacts with KATNB1 and KATNBL1. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: Cytoplasm
messages: Interacts with KATNB1 and KATNBL1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Midbody
messages: Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation.
messages: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays.
messages: The N-terminus is sufficient for interaction with microtubules, although high affinity binding to microtubules also requires an intact C-terminal domain and ATP, which promotes oligomerization.
messages: Ubiquitinated by the BCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation. Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted for proteasomal degradation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

89673:LOC114497806
gene id: 89673:LOC114497806
uniprot id: A0A7E6DP61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:LANCL1
gene id: 89673:LANCL1
uniprot id: A0A6J2LGN9
names: Similarity
messages: Belongs to the LanC-like protein family.

89673:ETV3
gene id: 89673:ETV3
uniprot id: A0A6J2KT37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity.

89673:DPP4
gene id: 89673:DPP4
uniprot id: A0A7E6DJX9
names: Subcellular Location Annotation
messages: Cell membrane
messages: invadopodium membrane
messages: lamellipodium membrane

89673:RIC8A
gene id: 89673:RIC8A
uniprot id: A0A6J2M1R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

89673:SPC25
gene id: 89673:SPC25
uniprot id: A0A6J2LDR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

89673:LACTB2
gene id: 89673:LACTB2
uniprot id: A0A6J2NAZ7
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

89673:LOC114499172
gene id: 89673:LOC114499172
uniprot id: A0A6J2LYL0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:KMO
gene id: 89673:KMO
uniprot id: A0A6J2N3Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
messages: Mitochondrion outer membrane

89673:LOC114513372
gene id: 89673:LOC114513372
uniprot id: A0A6J2NEU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TMEM38B
gene id: 89673:TMEM38B
uniprot id: A0A6J2N871
uniprot id: A0A7E6DFT3
uniprot id: A0A7E6DFU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

89673:TM4SF1
gene id: 89673:TM4SF1
uniprot id: A0A6J2L2C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

89673:LOC114507593
gene id: 89673:LOC114507593
uniprot id: A0A7E6CIQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3.
messages: Cytoplasm
messages: May play a role during erythropoiesis through regulation of transcription factor DDIT3.
messages: Nucleus

89673:MBD4
gene id: 89673:MBD4
uniprot id: A0A6J2M8Z4
uniprot id: A0A7E6E6J8
uniprot id: A0A7E6E6P2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with MLH1.
messages: Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
messages: Nucleus

89673:ING2
gene id: 89673:ING2
uniprot id: A0A6J2MTF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

89673:CLDN8
gene id: 89673:CLDN8
uniprot id: A0A6J2L0E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:LOC114500474
gene id: 89673:LOC114500474
uniprot id: A0A6J2LZ08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:AGK
gene id: 89673:AGK
uniprot id: A0A6J2MPQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

89673:RHBDL3
gene id: 89673:RHBDL3
uniprot id: A0A6J2M761
uniprot id: A0A6J2M8H0
uniprot id: A0A7E6ED96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Membrane

89673:ADAMTS13
gene id: 89673:ADAMTS13
uniprot id: A0A6J2N651
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:EGR3
gene id: 89673:EGR3
uniprot id: A0A6J2MCK9
uniprot id: A0A6J2MER6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

89673:CNNM1
gene id: 89673:CNNM1
uniprot id: A0A6J2LMV5
uniprot id: A0A6J2LQY9
uniprot id: A0A7E6DVH8
uniprot id: A0A7E6DWA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

89673:LOC114489533
gene id: 89673:LOC114489533
uniprot id: A0A6J2KV88
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:LOC114503979
gene id: 89673:LOC114503979
uniprot id: A0A6J2MHA2
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

89673:KCNS2
gene id: 89673:KCNS2
uniprot id: A0A6J2NIY6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:CLDN16
gene id: 89673:CLDN16
uniprot id: A0A6J2L5V5
uniprot id: A0A7E6D3X2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:ARL6IP5
gene id: 89673:ARL6IP5
uniprot id: A0A6J2M4E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

89673:ITGAE
gene id: 89673:ITGAE
uniprot id: A0A7E6ECP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:SMIM12
gene id: 89673:SMIM12
uniprot id: A0A6J2LJ45
names: Similarity
messages: Belongs to the SMIM12 family.

89673:LOC114504065
gene id: 89673:LOC114504065
uniprot id: A0A6J2MDZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MBLAC1
gene id: 89673:MBLAC1
uniprot id: A0A7E6DB82
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

89673:ITPRIPL1
gene id: 89673:ITPRIPL1
uniprot id: A0A6J2M4L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

89673:S1PR1
gene id: 89673:S1PR1
uniprot id: A0A6J2L094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:LOC114500384
gene id: 89673:LOC114500384
uniprot id: A0A6J2M469
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114491003
gene id: 89673:LOC114491003
uniprot id: A0A6J2KZW1
names: Subcellular Location Annotation
messages: Membrane

89673:PNMT
gene id: 89673:PNMT
uniprot id: A0A6J2MD53
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

89673:FGD5
gene id: 89673:FGD5
uniprot id: A0A6J2M5M4
uniprot id: A0A7E6E5N6
uniprot id: A0A7E6E6I3
names: Subcellular Location Annotation
messages: cytoskeleton

89673:SLC35D1
gene id: 89673:SLC35D1
uniprot id: A0A6J2LQD0
names: Subcellular Location Annotation
messages: Membrane

89673:PDLIM1
gene id: 89673:PDLIM1
uniprot id: A0A6J2LUR7
names: Subcellular Location Annotation
messages: Z line

89673:ATP8B3
gene id: 89673:ATP8B3
uniprot id: A0A6J2MG52
uniprot id: A0A7E6E8R5
uniprot id: A0A7E6E9R6
uniprot id: A0A7E6E9S1
uniprot id: A0A7E6EAD4
uniprot id: A0A7E6EAD9
uniprot id: A0A7E6EAS2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:BMS1
gene id: 89673:BMS1
uniprot id: A0A6J2LH13
uniprot id: A0A6J2LLZ7
uniprot id: A0A7E6DUG6
uniprot id: A0A7E6DUV6
names: Subcellular Location Annotation
messages: nucleolus

89673:ZNF496
gene id: 89673:ZNF496
uniprot id: A0A6J2NJH7
uniprot id: A0A7E6EBH3
names: Subcellular Location Annotation
messages: Nucleus

89673:ZNF503
gene id: 89673:ZNF503
uniprot id: A0A6J2LPD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

89673:ATG5
gene id: 89673:ATG5
uniprot id: A0A6J2LC46
uniprot id: A0A7E6DMP8
uniprot id: A0A7E6DNA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

89673:PAQR7
gene id: 89673:PAQR7
uniprot id: A0A6J2LNH8
uniprot id: A0A7E6DR48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

89673:IFI44L
gene id: 89673:IFI44L
uniprot id: A0A6J2LHZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI44 family.
messages: Cytoplasm

89673:DNM1L
gene id: 89673:DNM1L
uniprot id: A0A6J2N7K1
uniprot id: A0A6J2N7L0
uniprot id: A0A6J2N9E0
uniprot id: A0A6J2N9E4
uniprot id: A0A6J2N9Q6
uniprot id: A0A6J2NED0
uniprot id: A0A6J2NF08
uniprot id: A0A7E6D782
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: Endomembrane system
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: clathrin-coated pit
messages: cytosol
messages: synaptic vesicle membrane

89673:EPDR1
gene id: 89673:EPDR1
uniprot id: A0A6J2MPY2
uniprot id: A0A6J2MUA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ependymin family.
messages: Binds anionic lipids and gangliosides at acidic pH.
messages: Lysosome lumen

89673:JPT1
gene id: 89673:JPT1
uniprot id: A0A6J2M8Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

89673:CCNC
gene id: 89673:CCNC
uniprot id: A0A6J2LBX7
uniprot id: A0A6J2LFS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
messages: Nucleus

89673:MSX2
gene id: 89673:MSX2
uniprot id: A0A6J2MWI7
names: Subcellular Location Annotation
messages: Nucleus

89673:ACER2
gene id: 89673:ACER2
uniprot id: A0A6J2N8B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:ZKSCAN1
gene id: 89673:ZKSCAN1
uniprot id: A0A6J2L8G8
uniprot id: A0A6J2L9Q6
uniprot id: A0A6J2L9V2
uniprot id: A0A7E6D966
names: Subcellular Location Annotation
messages: Nucleus

89673:MLLT11
gene id: 89673:MLLT11
uniprot id: A0A7E6CWG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

89673:EIF4A3
gene id: 89673:EIF4A3
uniprot id: A0A6J2MB32
names: Similarity
messages: Belongs to the DEAD box helicase family.

89673:ATXN2
gene id: 89673:ATXN2
uniprot id: A0A6J2MU17
uniprot id: A0A6J2MZ31
uniprot id: A0A7E6CSG8
uniprot id: A0A7E6CSH0
uniprot id: A0A7E6CSH2
uniprot id: A0A7E6CSY1
uniprot id: A0A7E6CSY7
uniprot id: A0A7E6CT64
uniprot id: A0A7E6CT68
uniprot id: A0A7E6CV76
names: Similarity
messages: Belongs to the ataxin-2 family.

89673:KCNH2
gene id: 89673:KCNH2
uniprot id: A0A6J2MUL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
messages: Membrane

89673:PGK1
gene id: 89673:PGK1
uniprot id: A0A6J2ME10
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

89673:LOC114492615
gene id: 89673:LOC114492615
uniprot id: A0A6J2L565
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:GPR156
gene id: 89673:GPR156
uniprot id: A0A6J2L4Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

89673:LOC114507828
gene id: 89673:LOC114507828
uniprot id: A0A6J2MUU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:KIF23
gene id: 89673:KIF23
uniprot id: A0A7E6CF47
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:PRDM14
gene id: 89673:PRDM14
uniprot id: A0A6J2ND35
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114506386
gene id: 89673:LOC114506386
uniprot id: A0A7E6CFT4
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

89673:CPNE4
gene id: 89673:CPNE4
uniprot id: A0A6J2M3B5
uniprot id: A0A6J2M927
names: Similarity
messages: Belongs to the copine family.

89673:CCNA2
gene id: 89673:CCNA2
uniprot id: A0A6J2MB43
uniprot id: A0A7E6E9Q7
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

89673:FSHB
gene id: 89673:FSHB
uniprot id: A0A6J2M1I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

89673:SLC6A13
gene id: 89673:SLC6A13
uniprot id: A0A6J2N805
uniprot id: A0A7E6D552
uniprot id: A0A7E6D572
uniprot id: A0A7E6D5A3
uniprot id: A0A7E6D5U4
uniprot id: A0A7E6D812
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily.
messages: Cell membrane
messages: Membrane

89673:LOC114513188
gene id: 89673:LOC114513188
uniprot id: A0A6J2N8D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Component of the 60S subunit of the ribosome. Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus
messages: Ribosomal protein L40 is part of the 60S ribosomal subunit. Interacts with UBQLN1 (via UBA domain).

89673:DCLK1
gene id: 89673:DCLK1
uniprot id: A0A6J2MS06
uniprot id: A0A7E6CJJ0
uniprot id: A0A7E6CJP4
uniprot id: A0A7E6CLM0
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

89673:LOC114490142
gene id: 89673:LOC114490142
uniprot id: A0A6J2L0P6
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

89673:AARS2
gene id: 89673:AARS2
uniprot id: A0A6J2LBN2
uniprot id: A0A7E6DM80
names: Caution
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: ISGylated.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

89673:CLDN25
gene id: 89673:CLDN25
uniprot id: A0A6J2M0H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

89673:LOC114499302
gene id: 89673:LOC114499302
uniprot id: A0A6J2LYW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

89673:GNRH1
gene id: 89673:GNRH1
uniprot id: A0A6J2MCN0
uniprot id: A0A7E6EBA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.

89673:PAX7
gene id: 89673:PAX7
uniprot id: A0A6J2LQG4
uniprot id: A0A6J2LTM6
uniprot id: A0A7E6DQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

89673:TSPYL4
gene id: 89673:TSPYL4
uniprot id: A0A6J2LDL1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

89673:MEGF9
gene id: 89673:MEGF9
uniprot id: A0A6J2LP72
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:MINDY2
gene id: 89673:MINDY2
uniprot id: A0A6J2L1V8
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

89673:FAIM2
gene id: 89673:FAIM2
uniprot id: A0A6J2N872
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

89673:GJB5
gene id: 89673:GJB5
uniprot id: A0A6J2LTU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:C12H19orf54
gene id: 89673:C12H19orf54
uniprot id: A0A6J2MZN8
names: Similarity
messages: Belongs to the UPF0692 family.

89673:SLC15A3
gene id: 89673:SLC15A3
uniprot id: A0A6J2M1Y6
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

89673:ARCN1
gene id: 89673:ARCN1
uniprot id: A0A6J2LU92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

89673:ATP6V0E1
gene id: 89673:ATP6V0E1
uniprot id: A0A6J2MX56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

89673:LOC118501383
gene id: 89673:LOC118501383
uniprot id: A0A7E6E2E3
names: Subcellular Location Annotation
messages: Secreted

89673:ORAI2
gene id: 89673:ORAI2
uniprot id: A0A6J2M3E4
uniprot id: A0A7E6DBJ4
uniprot id: A0A7E6DCL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

89673:SLC25A4
gene id: 89673:SLC25A4
uniprot id: A0A6J2MSX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

89673:SLC2A9
gene id: 89673:SLC2A9
uniprot id: A0A6J2L7X5
uniprot id: A0A6J2LBV8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

89673:PIR
gene id: 89673:PIR
uniprot id: A0A6J2MLQ7
uniprot id: A0A7E6D071
uniprot id: A0A7E6D307
names: Similarity
messages: Belongs to the pirin family.

89673:HOXD3
gene id: 89673:HOXD3
uniprot id: A0A6J2LIA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:MBTD1
gene id: 89673:MBTD1
uniprot id: A0A6J2MC08
uniprot id: A0A6J2MEY9
uniprot id: A0A6J2MFG0
uniprot id: A0A7E6EF66
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114510797
gene id: 89673:LOC114510797
uniprot id: A0A6J2N4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NLRP12
gene id: 89673:NLRP12
uniprot id: A0A6J2N843
names: Similarity
messages: Belongs to the NLRP family.

89673:SLC4A11
gene id: 89673:SLC4A11
uniprot id: A0A7E6CET9
uniprot id: A0A7E6CEV2
uniprot id: A0A7E6CEZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

89673:GLO1
gene id: 89673:GLO1
uniprot id: A0A6J2LF90
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

89673:ISCU
gene id: 89673:ISCU
uniprot id: A0A6J2MWS1
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

89673:PSMC5
gene id: 89673:PSMC5
uniprot id: A0A7E6ECW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

89673:RPL23A
gene id: 89673:RPL23A
uniprot id: A0A6J2L9L8
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

89673:BSCL2
gene id: 89673:BSCL2
uniprot id: A0A6J2M1M8
uniprot id: A0A7E6E1S2
uniprot id: A0A7E6E1S7
uniprot id: A0A7E6E2A8
uniprot id: A0A7E6E2H1
uniprot id: A0A7E6E368
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:PRKCE
gene id: 89673:PRKCE
uniprot id: A0A6J2LUK9
uniprot id: A0A7E6DY45
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 (ITGB1) in cardiac fibroblasts. Phosphorylates MARCKS, which phosphorylates and activates PTK2/FAK, leading to the spread of cardiomyocytes. Involved in the control of the directional transport of ITGB1 in mesenchymal cells by phosphorylating vimentin (VIM), an intermediate filament (IF) protein. In epithelial cells, associates with and phosphorylates keratin-8 (KRT8), which induces targeting of desmoplakin at desmosomes and regulates cell-cell contact. Phosphorylates IQGAP1, which binds to CDC42, mediating epithelial cell-cell detachment prior to migration.
messages: Cell membrane
messages: Cytoplasm
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: cytoskeleton
messages: perinuclear region

89673:LOC114498829
gene id: 89673:LOC114498829
uniprot id: A0A6J2LSC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone-like Alba family.
messages: Component of nuclear RNase P and RNase MRP complexes. RNase P consists of a catalytic RNA moiety and 10 different protein chains; POP1, POP4, POP5, POP7, RPP14, RPP21, RPP25, RPP30, RPP38 and RPP40. Within the RNase P complex, POP1, POP7 and RPP25 form the 'finger' subcomplex, POP5, RPP14, RPP40 and homodimeric RPP30 form the 'palm' subcomplex, and RPP21, POP4 and RPP38 form the 'wrist' subcomplex. All subunits of the RNase P complex interact with the catalytic RNA. Several subunits of RNase P are also part of the RNase MRP complex. RNase MRP consists of a catalytic RNA moiety and about 8 protein subunits; POP1, POP7, RPP25, RPP30, RPP38, RPP40 and possibly also POP4 and POP5. Interacts with SMN1. POP7 forms a heterodimer with RPP25 that binds to the P3 stem loop of the catalytic RNA.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
messages: Cytoplasmic granule
messages: nucleolus

89673:TIMM13
gene id: 89673:TIMM13
uniprot id: A0A6J2M8F4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

89673:POU4F3
gene id: 89673:POU4F3
uniprot id: A0A6J2N2C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

89673:LOC114500718
gene id: 89673:LOC114500718
uniprot id: A0A6J2M4W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:EMP1
gene id: 89673:EMP1
uniprot id: A0A6J2NFE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

89673:LOC114507431
gene id: 89673:LOC114507431
uniprot id: A0A6J2MNG4
uniprot id: A0A7E6CJ94
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:GPT
gene id: 89673:GPT
uniprot id: A0A6J2NI26
uniprot id: A0A7E6E8X4
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

89673:NRTN
gene id: 89673:NRTN
uniprot id: A0A6J2MEW0
uniprot id: A0A7E6EA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

89673:EFNA4
gene id: 89673:EFNA4
uniprot id: A0A6J2KSS2
uniprot id: A0A6J2KWK9
uniprot id: A0A7E6CXX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114515153
gene id: 89673:LOC114515153
uniprot id: A0A7E6ECM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

89673:LOC114503731
gene id: 89673:LOC114503731
uniprot id: A0A6J2MFW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:BMPR2
gene id: 89673:BMPR2
uniprot id: A0A6J2LF76
uniprot id: A0A7E6DIP2
uniprot id: A0A7E6DIQ9
uniprot id: A0A7E6DIX7
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

89673:DOHH
gene id: 89673:DOHH
uniprot id: A0A6J2M9W0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

89673:RPA2
gene id: 89673:RPA2
uniprot id: A0A6J2LPU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

89673:LSM1
gene id: 89673:LSM1
uniprot id: A0A6J2L7P4
uniprot id: A0A6J2MSB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase. LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.

89673:DNAH12
gene id: 89673:DNAH12
uniprot id: A0A6J2M3Y8
names: Similarity
messages: Belongs to the dynein heavy chain family.

89673:LOC114501782
gene id: 89673:LOC114501782
uniprot id: A0A7E6E7M0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

89673:LOC114496160
gene id: 89673:LOC114496160
uniprot id: A0A6J2LMJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Component of the 60S subunit of the ribosome. Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus
messages: Ribosomal protein L40 is part of the 60S ribosomal subunit. Interacts with UBQLN1 (via UBA domain).

89673:TSC22D4
gene id: 89673:TSC22D4
uniprot id: A0A6J2N305
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

89673:RTN4
gene id: 89673:RTN4
uniprot id: A0A6J2LRI2
uniprot id: A0A6J2LSR5
uniprot id: A0A6J2LWK7
uniprot id: A0A6J2LWZ3
uniprot id: A0A7E6DY97
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:NCL
gene id: 89673:NCL
uniprot id: A0A6J2LAF3
uniprot id: A0A6J2LF21
uniprot id: A0A7E6DHV8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
messages: nucleolus

89673:ERG
gene id: 89673:ERG
uniprot id: A0A6J2L1Z4
uniprot id: A0A7E6D229
uniprot id: A0A7E6D279
uniprot id: A0A7E6D2T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:LOC114502872
gene id: 89673:LOC114502872
uniprot id: A0A6J2M9E5
uniprot id: A0A7E6DDZ7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inflammasome

89673:VEGFC
gene id: 89673:VEGFC
uniprot id: A0A6J2MSK0
uniprot id: A0A7E6CLA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

89673:KCNMA1
gene id: 89673:KCNMA1
uniprot id: A0A7E6DW21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

89673:RNF157
gene id: 89673:RNF157
uniprot id: A0A6J2MAW5
uniprot id: A0A7E6EF62
uniprot id: A0A7E6EFG6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

89673:TNFRSF21
gene id: 89673:TNFRSF21
uniprot id: A0A6J2LBD4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:AARS1
gene id: 89673:AARS1
uniprot id: A0A6J2NF71
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: ISGylated.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

89673:PPP4R3B
gene id: 89673:PPP4R3B
uniprot id: A0A6J2M0J2
uniprot id: A0A7E6DXC2
names: Similarity
messages: Belongs to the SMEK family.

89673:SNRPA1
gene id: 89673:SNRPA1
uniprot id: A0A7E6CRG0
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

89673:HUS1
gene id: 89673:HUS1
uniprot id: A0A6J2M5F8
uniprot id: A0A7E6CH41
names: Similarity
messages: Belongs to the HUS1 family.

89673:NRXN1
gene id: 89673:NRXN1
uniprot id: A0A6J2LR67
uniprot id: A0A6J2LR77
uniprot id: A0A6J2LR81
uniprot id: A0A6J2LR85
uniprot id: A0A6J2LR90
uniprot id: A0A6J2LSD5
uniprot id: A0A6J2LSD9
uniprot id: A0A6J2LSE9
uniprot id: A0A6J2LSF7
uniprot id: A0A6J2LT87
uniprot id: A0A6J2LT96
uniprot id: A0A6J2LTA8
uniprot id: A0A6J2LTB1
uniprot id: A0A6J2LW91
uniprot id: A0A6J2LW95
uniprot id: A0A6J2LWA1
uniprot id: A0A6J2LWB0
uniprot id: A0A6J2LWB5
uniprot id: A0A6J2LWM9
uniprot id: A0A6J2LWN4
uniprot id: A0A6J2LWN9
uniprot id: A0A6J2LWP8
uniprot id: A0A7E6E2Z4
uniprot id: A0A7E6E2Z8
uniprot id: A0A7E6E302
uniprot id: A0A7E6E3J5
uniprot id: A0A7E6E3K1
uniprot id: A0A7E6E3K4
uniprot id: A0A7E6E3L0
uniprot id: A0A7E6E3L7
uniprot id: A0A7E6E3N7
uniprot id: A0A7E6E3Q0
uniprot id: A0A7E6E4G6
uniprot id: A0A7E6E4H2
uniprot id: A0A7E6E4H6
uniprot id: A0A7E6E4I1
uniprot id: A0A7E6E4L2
uniprot id: A0A7E6E4M0
uniprot id: A0A7E6E4M6
uniprot id: A0A7E6E4M9
uniprot id: A0A7E6E4N6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:SSTR3
gene id: 89673:SSTR3
uniprot id: A0A6J2NA20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:AP1S2
gene id: 89673:AP1S2
uniprot id: A0A6J2MDR0
uniprot id: A0A6J2MFQ9
uniprot id: A0A6J2MFV8
uniprot id: A0A6J2MJR3
uniprot id: A0A7E6D045
uniprot id: A0A7E6D0S1
uniprot id: A0A7E6D2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

89673:PTGER3
gene id: 89673:PTGER3
uniprot id: A0A6J2LN33
uniprot id: A0A7E6DSQ5
uniprot id: A0A7E6DTC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:WASF2
gene id: 89673:WASF2
uniprot id: A0A7E6DRB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

89673:ATG2A
gene id: 89673:ATG2A
uniprot id: A0A6J2LW66
uniprot id: A0A6J2M0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

89673:QSOX2
gene id: 89673:QSOX2
uniprot id: A0A6J2MID7
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

89673:AGPAT5
gene id: 89673:AGPAT5
uniprot id: A0A6J2MSP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane

89673:SLC24A5
gene id: 89673:SLC24A5
uniprot id: A0A6J2L6T2
uniprot id: A0A7E6EBU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

89673:LOC114510218
gene id: 89673:LOC114510218
uniprot id: A0A6J2N3Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NDUFA3
gene id: 89673:NDUFA3
uniprot id: A0A6J2N1P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA3 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane
messages: Mitochondrion inner membrane

89673:SPP1
gene id: 89673:SPP1
uniprot id: A0A6J2L8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteopontin family.
messages: Secreted

89673:SERPINB9
gene id: 89673:SERPINB9
uniprot id: A0A7E6DTF4
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

89673:LOC114501732
gene id: 89673:LOC114501732
uniprot id: A0A6J2M2J6
names: Subcellular Location Annotation
messages: Nucleus

89673:AP4S1
gene id: 89673:AP4S1
uniprot id: A0A6J2LAD4
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

89673:AFF4
gene id: 89673:AFF4
uniprot id: A0A6J2MUG5
uniprot id: A0A7E6CUM8
names: Similarity
messages: Belongs to the AF4 family.

89673:KIDINS220
gene id: 89673:KIDINS220
uniprot id: A0A6J2LZI1
uniprot id: A0A6J2M0T4
uniprot id: A0A6J2M4K5
uniprot id: A0A6J2M4L0
uniprot id: A0A6J2M544
uniprot id: A0A7E6DXA1
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

89673:TAF2
gene id: 89673:TAF2
uniprot id: A0A6J2NCT9
uniprot id: A0A6J2NIJ6
uniprot id: A0A7E6E6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

89673:PSPH
gene id: 89673:PSPH
uniprot id: A0A6J2LQP8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

89673:HDAC8
gene id: 89673:HDAC8
uniprot id: A0A6J2MI64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

89673:PNRC1
gene id: 89673:PNRC1
uniprot id: A0A6J2LBI5
names: Subcellular Location Annotation
messages: Nucleus

89673:LGI1
gene id: 89673:LGI1
uniprot id: A0A6J2LQ25
uniprot id: A0A6J2LR94
uniprot id: A0A7E6DUK3
uniprot id: A0A7E6DVH7
names: Subcellular Location Annotation
messages: Secreted

89673:PIN4
gene id: 89673:PIN4
uniprot id: A0A6J2MFQ0
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

89673:MGMT
gene id: 89673:MGMT
uniprot id: A0A6J2LMD2
uniprot id: A0A7E6DVS7
names: Function
names: Similarity
messages: Belongs to the MGMT family.
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

89673:C3H16orf72
gene id: 89673:C3H16orf72
uniprot id: A0A6J2LNN3
names: Similarity
messages: Belongs to the TAPR1 family.

89673:SLC39A7
gene id: 89673:SLC39A7
uniprot id: A0A6J2LL42
names: Subcellular Location Annotation
messages: Membrane

89673:SSU72
gene id: 89673:SSU72
uniprot id: A0A6J2LQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

89673:AEBP1
gene id: 89673:AEBP1
uniprot id: A0A6J2KX53
uniprot id: A0A7E6CH19
uniprot id: A0A7E6CH84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

89673:EME1
gene id: 89673:EME1
uniprot id: A0A7E6EE49
names: Similarity
messages: Belongs to the EME1/MMS4 family.

89673:ABCG4
gene id: 89673:ABCG4
uniprot id: A0A7E6DZ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

89673:SFRP5
gene id: 89673:SFRP5
uniprot id: A0A6J2LS76
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:DOK6
gene id: 89673:DOK6
uniprot id: A0A6J2MJI8
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

89673:LOC114514180
gene id: 89673:LOC114514180
uniprot id: A0A7E6D6B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114503680
gene id: 89673:LOC114503680
uniprot id: A0A7E6E9C8
names: Subcellular Location Annotation
messages: Membrane

89673:SLC44A5
gene id: 89673:SLC44A5
uniprot id: A0A7E6DTD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

89673:CLK4
gene id: 89673:CLK4
uniprot id: A0A6J2MUH8
uniprot id: A0A6J2MZ26
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:MAP2K5
gene id: 89673:MAP2K5
uniprot id: A0A6J2L3G1
uniprot id: A0A6J2L5D5
uniprot id: A0A7E6CEL9
uniprot id: A0A7E6CEM6
uniprot id: A0A7E6CEM7
uniprot id: A0A7E6CF61
uniprot id: A0A7E6CFA2
uniprot id: A0A7E6CGQ0
uniprot id: A0A7E6CGQ5
uniprot id: A0A7E6CGS5
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:SERPING1
gene id: 89673:SERPING1
uniprot id: A0A6J2M168
uniprot id: A0A7E6E1D2
uniprot id: A0A7E6E221
uniprot id: A0A7E6E2R8
uniprot id: A0A7E6E2T3
names: Similarity
messages: Belongs to the serpin family.

89673:GABBR1
gene id: 89673:GABBR1
uniprot id: A0A6J2LAW9
uniprot id: A0A7E6DKJ7
uniprot id: A0A7E6DKJ8
uniprot id: A0A7E6DKU7
uniprot id: A0A7E6DKX4
uniprot id: A0A7E6DL77
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:APOOL
gene id: 89673:APOOL
uniprot id: A0A6J2KXE8
uniprot id: A0A7E6D1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

89673:NOS2
gene id: 89673:NOS2
uniprot id: A0A6J2M9R3
uniprot id: A0A7E6EDY2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

89673:LOC114489539
gene id: 89673:LOC114489539
uniprot id: A0A6J2L148
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:TXN
gene id: 89673:TXN
uniprot id: A0A6J2LZA8
names: Similarity
messages: Belongs to the thioredoxin family.

89673:LOC114502438
gene id: 89673:LOC114502438
uniprot id: A0A6J2MA44
names: Similarity
messages: Belongs to the intermediate filament family.

89673:LARP7
gene id: 89673:LARP7
uniprot id: A0A6J2MBS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LARP7 family.
messages: nucleoplasm

89673:LOC114511295
gene id: 89673:LOC114511295
uniprot id: A0A6J2N6C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

89673:IL4
gene id: 89673:IL4
uniprot id: A0A6J2N3G4
names: Function
messages: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.

89673:PROKR1
gene id: 89673:PROKR1
uniprot id: A0A6J2LXV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

89673:LOC114500253
gene id: 89673:LOC114500253
uniprot id: A0A6J2M0A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PMM1
gene id: 89673:PMM1
uniprot id: A0A6J2NE25
uniprot id: A0A7E6D9A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

89673:SLC25A40
gene id: 89673:SLC25A40
uniprot id: A0A7E6CJY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis.
messages: Mitochondrion inner membrane

89673:HGFAC
gene id: 89673:HGFAC
uniprot id: A0A6J2KYE0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:PGM2
gene id: 89673:PGM2
uniprot id: A0A6J2L761
names: Similarity
messages: Belongs to the phosphohexose mutase family.

89673:ACSS3
gene id: 89673:ACSS3
uniprot id: A0A6J2NFP6
uniprot id: A0A7E6D5K7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:LOC114500021
gene id: 89673:LOC114500021
uniprot id: A0A6J2LZE7
uniprot id: A0A7E6E2A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPT transporter family. SLC35C subfamily.
messages: Membrane

89673:ADIPOR2
gene id: 89673:ADIPOR2
uniprot id: A0A6J2NB14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

89673:CLDN1
gene id: 89673:CLDN1
uniprot id: A0A6J2L3X2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:CENPC
gene id: 89673:CENPC
uniprot id: A0A6J2L552
uniprot id: A0A7E6DCL0
uniprot id: A0A7E6DCR9
uniprot id: A0A7E6DCS3
uniprot id: A0A7E6DD20
uniprot id: A0A7E6DDC3
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

89673:SLCO2B1
gene id: 89673:SLCO2B1
uniprot id: A0A6J2M0D0
uniprot id: A0A7E6DZT1
uniprot id: A0A7E6E0A2
uniprot id: A0A7E6E0T5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TCN1
gene id: 89673:TCN1
uniprot id: A0A7E6E1H2
uniprot id: A0A7E6E2X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

89673:BAZ1B
gene id: 89673:BAZ1B
uniprot id: A0A6J2LQR1
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114503722
gene id: 89673:LOC114503722
uniprot id: A0A7E6EG56
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

89673:LOC114505286
gene id: 89673:LOC114505286
uniprot id: A0A6J2MM56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

89673:ITGB3
gene id: 89673:ITGB3
uniprot id: A0A6J2MCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

89673:BRI3
gene id: 89673:BRI3
uniprot id: A0A6J2MWF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRI3 family.
messages: Membrane
messages: perinuclear region

89673:KCNMB3
gene id: 89673:KCNMB3
uniprot id: A0A7E6D2U8
names: Subcellular Location Annotation
messages: Membrane

89673:CCL28
gene id: 89673:CCL28
uniprot id: A0A7E6DA25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

89673:UBE2L3
gene id: 89673:UBE2L3
uniprot id: A0A6J2MV58
uniprot id: A0A6J2N084
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:PACSIN2
gene id: 89673:PACSIN2
uniprot id: A0A6J2N914
uniprot id: A0A6J2NAQ5
uniprot id: A0A6J2NFS4
uniprot id: A0A6J2NGI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: caveola
messages: cytoskeleton
messages: ruffle membrane

89673:EAF2
gene id: 89673:EAF2
uniprot id: A0A6J2L2K7
names: Similarity
messages: Belongs to the EAF family.

89673:CES5A
gene id: 89673:CES5A
uniprot id: A0A6J2KR09
uniprot id: A0A7E6CLF7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

89673:NAPA
gene id: 89673:NAPA
uniprot id: A0A6J2N0C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

89673:LOC114507636
gene id: 89673:LOC114507636
uniprot id: A0A6J2MPD1
uniprot id: A0A7E6DAB2
uniprot id: A0A7E6DBG2
uniprot id: A0A7E6DD47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

89673:CELF2
gene id: 89673:CELF2
uniprot id: A0A6J2L5U3
uniprot id: A0A6J2L6J5
uniprot id: A0A7E6DMZ5
uniprot id: A0A7E6DN01
uniprot id: A0A7E6DN08
uniprot id: A0A7E6DNH2
uniprot id: A0A7E6DNN2
uniprot id: A0A7E6DNU4
uniprot id: A0A7E6DNU9
uniprot id: A0A7E6DNV5
uniprot id: A0A7E6DNX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

89673:KDELR1
gene id: 89673:KDELR1
uniprot id: A0A6J2N198
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TPX2
gene id: 89673:TPX2
uniprot id: A0A6J2MKB3
uniprot id: A0A7E6CF22
uniprot id: A0A7E6CF64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

89673:AHCYL1
gene id: 89673:AHCYL1
uniprot id: A0A6J2KT98
uniprot id: A0A6J2KTT9
uniprot id: A0A6J2KX35
uniprot id: A0A7E6CZS3
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

89673:MPO
gene id: 89673:MPO
uniprot id: A0A6J2MDK1
names: Cofactor
messages: Binds 1 Ca(2+) ion per monomer.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group covalently per monomer.

89673:LOC114496190
gene id: 89673:LOC114496190
uniprot id: A0A6J2LNB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

89673:MTMR4
gene id: 89673:MTMR4
uniprot id: A0A6J2MBC0
uniprot id: A0A6J2ME88
uniprot id: A0A6J2MEQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

89673:TM4SF5
gene id: 89673:TM4SF5
uniprot id: A0A6J2NEJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

89673:PTCD3
gene id: 89673:PTCD3
uniprot id: A0A6J2M470
uniprot id: A0A7E6DY53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

89673:PDCD11
gene id: 89673:PDCD11
uniprot id: A0A6J2LKP4
uniprot id: A0A7E6DVT9
uniprot id: A0A7E6DW63
names: Subcellular Location Annotation
messages: nucleolus

89673:LHX5
gene id: 89673:LHX5
uniprot id: A0A6J2MXF3
names: Subcellular Location Annotation
messages: Nucleus

89673:KCNJ2
gene id: 89673:KCNJ2
uniprot id: A0A6J2M7M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Membrane

89673:UGT8
gene id: 89673:UGT8
uniprot id: A0A6J2M8L9
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

89673:STARD8
gene id: 89673:STARD8
uniprot id: A0A6J2MG17
uniprot id: A0A7E6D1N5
names: Subcellular Location Annotation
messages: Cytoplasm

89673:GPN3
gene id: 89673:GPN3
uniprot id: A0A6J2MTX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

89673:KRT72
gene id: 89673:KRT72
uniprot id: A0A6J2N8L1
uniprot id: A0A6J2ND43
names: Similarity
messages: Belongs to the intermediate filament family.

89673:AMBN
gene id: 89673:AMBN
uniprot id: A0A6J2L791
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ameloblastin family.
messages: Involved in the mineralization and structural organization of enamel.
messages: extracellular matrix

89673:LOC114507234
gene id: 89673:LOC114507234
uniprot id: A0A6J2MSL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:KRT24
gene id: 89673:KRT24
uniprot id: A0A6J2MAZ4
names: Similarity
messages: Belongs to the intermediate filament family.

89673:FAM163A
gene id: 89673:FAM163A
uniprot id: A0A6J2N4J2
uniprot id: A0A7E6CYB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

89673:CD180
gene id: 89673:CD180
uniprot id: A0A6J2MHG7
uniprot id: A0A7E6DBW4
names: Similarity
messages: Belongs to the Toll-like receptor family.

89673:PACC1
gene id: 89673:PACC1
uniprot id: A0A6J2N3M8
uniprot id: A0A7E6CVT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

89673:OLFM1
gene id: 89673:OLFM1
uniprot id: A0A6J2MH70
uniprot id: A0A6J2MH77
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

89673:CD164L2
gene id: 89673:CD164L2
uniprot id: A0A6J2LPH1
uniprot id: A0A6J2LSL4
uniprot id: A0A7E6DQK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

89673:SELENOT
gene id: 89673:SELENOT
uniprot id: A0A6J2KWA2
names: Similarity
messages: Belongs to the SelWTH family. Selenoprotein T subfamily.

89673:DOCK4
gene id: 89673:DOCK4
uniprot id: A0A6J2MNW2
uniprot id: A0A7E6CH67
uniprot id: A0A7E6CJ68
names: Similarity
messages: Belongs to the DOCK family.

89673:PARP2
gene id: 89673:PARP2
uniprot id: A0A6J2L347
uniprot id: A0A7E6E5V6
uniprot id: A0A7E6E5X2
uniprot id: A0A7E6E5Y3
uniprot id: A0A7E6E6S9
uniprot id: A0A7E6E6V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

89673:TRAPPC11
gene id: 89673:TRAPPC11
uniprot id: A0A6J2MWV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPPC11 family.
messages: Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
messages: cis-Golgi network

89673:LRRC8D
gene id: 89673:LRRC8D
uniprot id: A0A6J2LVG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

89673:LOC114510749
gene id: 89673:LOC114510749
uniprot id: A0A6J2MXZ7
names: Similarity
messages: Belongs to the MHC class I family.

89673:TMEM129
gene id: 89673:TMEM129
uniprot id: A0A6J2KVZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

89673:ELOF1
gene id: 89673:ELOF1
uniprot id: A0A6J2MCY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

89673:PTAR1
gene id: 89673:PTAR1
uniprot id: A0A6J2LV46
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

89673:KCNH7
gene id: 89673:KCNH7
uniprot id: A0A7E6DK22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
messages: Membrane

89673:TMCO3
gene id: 89673:TMCO3
uniprot id: A0A6J2MQN3
uniprot id: A0A6J2MWX9
names: Subcellular Location Annotation
messages: Membrane

89673:NDRG1
gene id: 89673:NDRG1
uniprot id: A0A6J2NBG9
names: Similarity
messages: Belongs to the NDRG family.

89673:LOC114491318
gene id: 89673:LOC114491318
uniprot id: A0A7E6DBD2
names: Subcellular Location Annotation
messages: extracellular exosome

89673:LOC114493836
gene id: 89673:LOC114493836
uniprot id: A0A7E6DHJ0
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

89673:KYNU
gene id: 89673:KYNU
uniprot id: A0A6J2LDP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:NAP1L4
gene id: 89673:NAP1L4
uniprot id: A0A6J2LTW3
uniprot id: A0A6J2LZH9
uniprot id: A0A7E6E3Y3
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

89673:ANXA2
gene id: 89673:ANXA2
uniprot id: A0A6J2L7B4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
messages: Membrane
messages: basement membrane

89673:TINAGL1
gene id: 89673:TINAGL1
uniprot id: A0A6J2LV18
names: Similarity
messages: Belongs to the peptidase C1 family.

89673:NMNAT3
gene id: 89673:NMNAT3
uniprot id: A0A6J2M408
uniprot id: A0A7E6E5K7
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

89673:POLR2I
gene id: 89673:POLR2I
uniprot id: A0A6J2N7C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

89673:CCL20
gene id: 89673:CCL20
uniprot id: A0A6J2LBL6
uniprot id: A0A7E6DI13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

89673:KRT39
gene id: 89673:KRT39
uniprot id: A0A6J2MD64
names: Similarity
messages: Belongs to the intermediate filament family.

89673:CITED4
gene id: 89673:CITED4
uniprot id: A0A7E6DS45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

89673:MUS81
gene id: 89673:MUS81
uniprot id: A0A7E6E3H2
uniprot id: A0A7E6E4Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

89673:ALKBH5
gene id: 89673:ALKBH5
uniprot id: A0A6J2NED2
names: Subcellular Location Annotation
names: Subunit
messages: Monomer.
messages: Nucleus speckle

89673:NDUFA1
gene id: 89673:NDUFA1
uniprot id: A0A6J2MH94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:LOC118499396
gene id: 89673:LOC118499396
uniprot id: A0A7E6D9Y5
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

89673:HMCN2
gene id: 89673:HMCN2
uniprot id: A0A7E6DGX4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:PLSCR4
gene id: 89673:PLSCR4
uniprot id: A0A7E6D3E6
uniprot id: A0A7E6D410
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

89673:LOXL1
gene id: 89673:LOXL1
uniprot id: A0A6J2L774
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

89673:MEP1A
gene id: 89673:MEP1A
uniprot id: A0A7E6DHL3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114510764
gene id: 89673:LOC114510764
uniprot id: A0A6J2MZN9
names: Similarity
messages: Belongs to the MHC class I family.

89673:GFUS
gene id: 89673:GFUS
uniprot id: A0A6J2NI69
uniprot id: A0A7E6E7X4
uniprot id: A0A7E6E8H7
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

89673:FOXS1
gene id: 89673:FOXS1
uniprot id: A0A6J2MLA4
names: Subcellular Location Annotation
messages: Nucleus

89673:PFKL
gene id: 89673:PFKL
uniprot id: A0A6J2KZK7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TRAPPC3
gene id: 89673:TRAPPC3
uniprot id: A0A6J2LJ34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

89673:UBA1
gene id: 89673:UBA1
uniprot id: A0A6J2MF59
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

89673:CUL3
gene id: 89673:CUL3
uniprot id: A0A6J2LGF8
uniprot id: A0A6J2LLC4
uniprot id: A0A7E6DI18
names: Similarity
messages: Belongs to the cullin family.

89673:SLC8B1
gene id: 89673:SLC8B1
uniprot id: A0A7E6CS02
names: Subcellular Location Annotation
messages: Membrane

89673:MTCH1
gene id: 89673:MTCH1
uniprot id: A0A6J2LD86
uniprot id: A0A6J2LHZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:ODR4
gene id: 89673:ODR4
uniprot id: A0A6J2N4U6
uniprot id: A0A7E6CXS4
names: Function
names: Similarity
messages: Belongs to the ODR-4 family.
messages: May play a role in the trafficking of a subset of G-protein coupled receptors.

89673:TBR1
gene id: 89673:TBR1
uniprot id: A0A6J2LLU1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:SHFL
gene id: 89673:SHFL
uniprot id: A0A6J2M8W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHFL family.
messages: Nucleus
messages: P-body

89673:TSPO2
gene id: 89673:TSPO2
uniprot id: A0A6J2LJN0
uniprot id: A0A7E6DLG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

89673:DDX41
gene id: 89673:DDX41
uniprot id: A0A6J2MWD9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

89673:IGF1R
gene id: 89673:IGF1R
uniprot id: A0A6J2KRI7
uniprot id: A0A7E6CPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

89673:RGS2
gene id: 89673:RGS2
uniprot id: A0A6J2N582
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: nucleolus

89673:LOC114495196
gene id: 89673:LOC114495196
uniprot id: A0A7E6DHM2
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

89673:CTSH
gene id: 89673:CTSH
uniprot id: A0A6J2KTY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

89673:RARS1
gene id: 89673:RARS1
uniprot id: A0A6J2N2R6
uniprot id: A0A7E6CUR4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

89673:CSNK1D
gene id: 89673:CSNK1D
uniprot id: A0A6J2M7J7
uniprot id: A0A6J2M8W4
uniprot id: A0A6J2M9H6
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LCLAT1
gene id: 89673:LCLAT1
uniprot id: A0A6J2M1T8
uniprot id: A0A7E6DWT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane

89673:ANO3
gene id: 89673:ANO3
uniprot id: A0A6J2LYJ6
uniprot id: A0A6J2M201
uniprot id: A0A6J2M206
uniprot id: A0A7E6E0M5
uniprot id: A0A7E6E0Z6
uniprot id: A0A7E6E1V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

89673:LOC114510271
gene id: 89673:LOC114510271
uniprot id: A0A6J2MX27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PGM5
gene id: 89673:PGM5
uniprot id: A0A6J2MZW0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

89673:PANX3
gene id: 89673:PANX3
uniprot id: A0A6J2MY87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

89673:ARMC1
gene id: 89673:ARMC1
uniprot id: A0A6J2NCB6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

89673:BEST2
gene id: 89673:BEST2
uniprot id: A0A6J2MDW5
uniprot id: A0A7E6EAD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

89673:IZUMO2
gene id: 89673:IZUMO2
uniprot id: A0A7E6CP71
names: Similarity
messages: Belongs to the Izumo family.

89673:ST3GAL3
gene id: 89673:ST3GAL3
uniprot id: A0A6J2LQ24
uniprot id: A0A6J2LT34
uniprot id: A0A6J2LT59
uniprot id: A0A7E6DRH6
uniprot id: A0A7E6DS62
uniprot id: A0A7E6DS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:LOC114504229
gene id: 89673:LOC114504229
uniprot id: A0A6J2MHM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

89673:LOC118501446
gene id: 89673:LOC118501446
uniprot id: A0A7E6E2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

89673:IQSEC1
gene id: 89673:IQSEC1
uniprot id: A0A6J2KYU9
uniprot id: A0A6J2KZE9
uniprot id: A0A6J2KZF4
uniprot id: A0A6J2L127
uniprot id: A0A6J2L129
uniprot id: A0A6J2L2U9
uniprot id: A0A6J2L4I2
uniprot id: A0A6J2L4I7
uniprot id: A0A7E6D4J2
uniprot id: A0A7E6D4N0
uniprot id: A0A7E6D4Q9
uniprot id: A0A7E6D585
uniprot id: A0A7E6D588
uniprot id: A0A7E6D7D3
names: Similarity
messages: Belongs to the BRAG family.

89673:TMEM86A
gene id: 89673:TMEM86A
uniprot id: A0A6J2LX05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

89673:ATP23
gene id: 89673:ATP23
uniprot id: A0A6J2N650
uniprot id: A0A6J2N7W1
uniprot id: A0A7E6D8M3
names: Similarity
messages: Belongs to the peptidase M76 family.

89673:USP11
gene id: 89673:USP11
uniprot id: A0A7E6CZ15
uniprot id: A0A7E6CZ18
uniprot id: A0A7E6CZF8
uniprot id: A0A7E6CZG2
uniprot id: A0A7E6CZZ1
uniprot id: A0A7E6D1N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

89673:AASDHPPT
gene id: 89673:AASDHPPT
uniprot id: A0A6J2M159
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

89673:LOC114495205
gene id: 89673:LOC114495205
uniprot id: A0A6J2LJE4
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

89673:PSMG1
gene id: 89673:PSMG1
uniprot id: A0A6J2L396
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PSMG1 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.
messages: Cytoplasm
messages: Forms a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer interacts directly with the PSMA5 and PSMA7 proteasome alpha subunits.
messages: Forms a heterodimer with psmg2.

89673:KIFC3
gene id: 89673:KIFC3
uniprot id: A0A6J2KSR9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:ZDHHC8
gene id: 89673:ZDHHC8
uniprot id: A0A6J2MXQ2
uniprot id: A0A6J2N320
uniprot id: A0A7E6CRD2
uniprot id: A0A7E6CRU0
uniprot id: A0A7E6CU16
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:ITGA1
gene id: 89673:ITGA1
uniprot id: A0A6J2MP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:GPR132
gene id: 89673:GPR132
uniprot id: A0A7E6D2V4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:AKR1A1
gene id: 89673:AKR1A1
uniprot id: A0A6J2LT33
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

89673:ERGIC1
gene id: 89673:ERGIC1
uniprot id: A0A6J2MY34
uniprot id: A0A7E6CTN8
uniprot id: A0A7E6CUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

89673:TXNRD1
gene id: 89673:TXNRD1
uniprot id: A0A6J2ND95
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

89673:ARHGDIB
gene id: 89673:ARHGDIB
uniprot id: A0A6J2NBQ4
names: Similarity
messages: Belongs to the Rho GDI family.

89673:SERPINI1
gene id: 89673:SERPINI1
uniprot id: A0A6J2L247
names: Similarity
messages: Belongs to the serpin family.

89673:PRPS1
gene id: 89673:PRPS1
uniprot id: A0A6J2MJT9
uniprot id: A0A7E6D1E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

89673:LOC114493171
gene id: 89673:LOC114493171
uniprot id: A0A6J2LDJ3
names: Similarity
messages: Belongs to the FXYD family.

89673:LOC114489087
gene id: 89673:LOC114489087
uniprot id: A0A7E6CWP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

89673:MIOS
gene id: 89673:MIOS
uniprot id: A0A6J2MNT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat mio family.
messages: Lysosome membrane

89673:LOC114488824
gene id: 89673:LOC114488824
uniprot id: A0A6J2KSX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC118502267
gene id: 89673:LOC118502267
uniprot id: A0A7E6EFK7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

89673:CCNE2
gene id: 89673:CCNE2
uniprot id: A0A6J2NBJ2
uniprot id: A0A6J2NDM0
uniprot id: A0A6J2NID0
uniprot id: A0A7E6E6E4
uniprot id: A0A7E6E796
uniprot id: A0A7E6E7W7
names: Similarity
messages: Belongs to the cyclin family. Cyclin E subfamily.

89673:LOC114489377
gene id: 89673:LOC114489377
uniprot id: A0A6J2KUL1
uniprot id: A0A6J2KUQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:RPL31
gene id: 89673:RPL31
uniprot id: A0A6J2LWR9
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

89673:SIRT5
gene id: 89673:SIRT5
uniprot id: A0A6J2LUZ3
uniprot id: A0A7E6DTR5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-102 and Arg-105) that bind to malonylated and succinylated substrates and define the specificity.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-63 and Arg-66) that bind to malonylated and succinylated substrates and define the specificity.
messages: Mitochondrion
messages: Monomer. Homodimer. Interacts with CPS1.
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinylation and activation of HMGCS2. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as Uox.
messages: Nucleus
messages: cytosol

89673:ROR1
gene id: 89673:ROR1
uniprot id: A0A6J2LJK6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TXLNG
gene id: 89673:TXLNG
uniprot id: A0A6J2ME92
uniprot id: A0A7E6D3I8
names: Similarity
messages: Belongs to the taxilin family.

89673:GTF2IRD1
gene id: 89673:GTF2IRD1
uniprot id: A0A7E6DCI6
names: Subcellular Location Annotation
messages: Nucleus

89673:PRDM1
gene id: 89673:PRDM1
uniprot id: A0A6J2LJL7
uniprot id: A0A7E6DMR2
uniprot id: A0A7E6DN63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

89673:TMSB4X
gene id: 89673:TMSB4X
uniprot id: A0A7E6CZ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

89673:ANKS6
gene id: 89673:ANKS6
uniprot id: A0A6J2N4D7
uniprot id: A0A7E6DFP6
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

89673:LOC114500145
gene id: 89673:LOC114500145
uniprot id: A0A6J2M2W4
uniprot id: A0A7E6DYF0
names: Similarity
messages: Belongs to the AHA1 family.

89673:OGDHL
gene id: 89673:OGDHL
uniprot id: A0A6J2LRT0
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

89673:NOXA1
gene id: 89673:NOXA1
uniprot id: A0A7E6D9N0
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

89673:HSPA9
gene id: 89673:HSPA9
uniprot id: A0A6J2MZ12
names: Similarity
messages: Belongs to the heat shock protein 70 family.

89673:PARVB
gene id: 89673:PARVB
uniprot id: A0A6J2N8R9
uniprot id: A0A7E6DBH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: Cell membrane
messages: cytoskeleton

89673:NKX2-1
gene id: 89673:NKX2-1
uniprot id: A0A6J2LE09
names: Subcellular Location Annotation
messages: Nucleus

89673:PDE1B
gene id: 89673:PDE1B
uniprot id: A0A6J2NDA4
uniprot id: A0A7E6D943
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:PPP3R2
gene id: 89673:PPP3R2
uniprot id: A0A6J2N367
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

89673:LOC114499793
gene id: 89673:LOC114499793
uniprot id: A0A6J2M1Y3
uniprot id: A0A7E6E128
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

89673:ATRAID
gene id: 89673:ATRAID
uniprot id: A0A6J2LVR5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CIAO1
gene id: 89673:CIAO1
uniprot id: A0A6J2LST8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex. Component of the MMXD complex, which includes CIAO1, ERCC2, FAM96B, MMS19 and SLC25A5. Interacts with WT1. Interacts with FAM96A.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.

89673:HDC
gene id: 89673:HDC
uniprot id: A0A6J2L745
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

89673:KRTCAP3
gene id: 89673:KRTCAP3
uniprot id: A0A6J2LRQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

89673:KCNU1
gene id: 89673:KCNU1
uniprot id: A0A6J2MRI2
names: Subcellular Location Annotation
messages: Membrane

89673:CNTNAP1
gene id: 89673:CNTNAP1
uniprot id: A0A6J2MCM5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: paranodal septate junction

89673:LOC114500731
gene id: 89673:LOC114500731
uniprot id: A0A6J2M1Z0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:AMDHD2
gene id: 89673:AMDHD2
uniprot id: A0A6J2LFD2
uniprot id: A0A7E6D9B9
uniprot id: A0A7E6DA81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.
messages: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.

89673:DOP1A
gene id: 89673:DOP1A
uniprot id: A0A6J2LFB3
uniprot id: A0A6J2LGB7
uniprot id: A0A6J2LGC5
uniprot id: A0A6J2LK24
uniprot id: A0A7E6DMC8
uniprot id: A0A7E6DMW2
uniprot id: A0A7E6DN60
names: Similarity
messages: Belongs to the dopey family.

89673:MAPK8IP3
gene id: 89673:MAPK8IP3
uniprot id: A0A6J2MU08
uniprot id: A0A6J2MU33
uniprot id: A0A6J2MVT4
uniprot id: A0A6J2MVW0
uniprot id: A0A6J2MVZ4
uniprot id: A0A6J2N087
uniprot id: A0A6J2N097
uniprot id: A0A6J2N0H0
uniprot id: A0A6J2N0X7
uniprot id: A0A6J2N118
uniprot id: A0A6J2N146
uniprot id: A0A7E6DC30
uniprot id: A0A7E6DC36
uniprot id: A0A7E6DCB5
uniprot id: A0A7E6DD50
uniprot id: A0A7E6DD53
uniprot id: A0A7E6DDM5
uniprot id: A0A7E6DDM6
names: Similarity
messages: Belongs to the JIP scaffold family.

89673:NRP2
gene id: 89673:NRP2
uniprot id: A0A6J2LIJ6
uniprot id: A0A6J2LL32
uniprot id: A0A7E6DIJ3
uniprot id: A0A7E6DIY2
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CAMSAP2
gene id: 89673:CAMSAP2
uniprot id: A0A6J2N501
uniprot id: A0A7E6CYL6
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

89673:BIRC2
gene id: 89673:BIRC2
uniprot id: A0A6J2LWU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

89673:LOC114500378
gene id: 89673:LOC114500378
uniprot id: A0A6J2LZU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114500754
gene id: 89673:LOC114500754
uniprot id: A0A6J2M501
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114498387
gene id: 89673:LOC114498387
uniprot id: A0A6J2LQN1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

89673:CPN1
gene id: 89673:CPN1
uniprot id: A0A6J2LMZ4
names: Similarity
messages: Belongs to the peptidase M14 family.

89673:IPO5
gene id: 89673:IPO5
uniprot id: A0A6J2MT72
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:FLI1
gene id: 89673:FLI1
uniprot id: A0A6J2MZN2
uniprot id: A0A7E6CSQ4
uniprot id: A0A7E6CSR1
uniprot id: A0A7E6CT74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:LOC114499512
gene id: 89673:LOC114499512
uniprot id: A0A7E6DWT6
names: Similarity
messages: Belongs to the peptidase M10A family.

89673:ZNF711
gene id: 89673:ZNF711
uniprot id: A0A6J2MF99
uniprot id: A0A7E6D1M6
names: Subcellular Location Annotation
messages: Nucleus

89673:SURF4
gene id: 89673:SURF4
uniprot id: A0A6J2LV36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

89673:SAMHD1
gene id: 89673:SAMHD1
uniprot id: A0A6J2MKD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAMHD1 family.
messages: Chromosome

89673:EPS8L2
gene id: 89673:EPS8L2
uniprot id: A0A6J2LZ06
uniprot id: A0A7E6E2J2
names: Similarity
messages: Belongs to the EPS8 family.

89673:LOC114498925
gene id: 89673:LOC114498925
uniprot id: A0A6J2LXM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PPP3CC
gene id: 89673:PPP3CC
uniprot id: A0A6J2M9N4
uniprot id: A0A6J2MA31
uniprot id: A0A6J2MDE6
uniprot id: A0A7E6EBW0
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

89673:BBOX1
gene id: 89673:BBOX1
uniprot id: A0A6J2M3M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
messages: Cytoplasm

89673:LOC114490347
gene id: 89673:LOC114490347
uniprot id: A0A6J2KZS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least TP53RK, TPRKB, OSGEP and LAGE3; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
messages: Cytoplasm
messages: Nucleus

89673:CPZ
gene id: 89673:CPZ
uniprot id: A0A6J2KZZ4
names: Similarity
messages: Belongs to the peptidase M14 family.

89673:SLC25A28
gene id: 89673:SLC25A28
uniprot id: A0A6J2LM95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:ASIC3
gene id: 89673:ASIC3
uniprot id: A0A6J2MUX7
names: Subcellular Location Annotation
messages: Membrane

89673:SNRPE
gene id: 89673:SNRPE
uniprot id: A0A6J2N3X7
uniprot id: A0A7E6CVF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

89673:BMPR1A
gene id: 89673:BMPR1A
uniprot id: A0A6J2LGS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

89673:GTPBP1
gene id: 89673:GTPBP1
uniprot id: A0A6J2N8G6
uniprot id: A0A6J2NA66
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

89673:NUDT19
gene id: 89673:NUDT19
uniprot id: A0A6J2KR42
names: Similarity
messages: Belongs to the Nudix hydrolase family.

89673:LOC114500486
gene id: 89673:LOC114500486
uniprot id: A0A7E6E180
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114501854
gene id: 89673:LOC114501854
uniprot id: A0A6J2M814
uniprot id: A0A7E6E3Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

89673:FBXO25
gene id: 89673:FBXO25
uniprot id: A0A6J2MQV5
uniprot id: A0A6J2MSM6
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114489386
gene id: 89673:LOC114489386
uniprot id: A0A6J2L0Q6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:SCGB1C1
gene id: 89673:SCGB1C1
uniprot id: A0A6J2M2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

89673:CARMIL2
gene id: 89673:CARMIL2
uniprot id: A0A6J2KRD0
uniprot id: A0A7E6CP40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

89673:DPYD
gene id: 89673:DPYD
uniprot id: A0A6J2L0S5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

89673:FAM102B
gene id: 89673:FAM102B
uniprot id: A0A6J2KXE9
names: Similarity
messages: Belongs to the FAM102 family.

89673:SNX31
gene id: 89673:SNX31
uniprot id: A0A7E6E739
names: Similarity
messages: Belongs to the sorting nexin family.

89673:LOC114495584
gene id: 89673:LOC114495584
uniprot id: A0A6J2LKX3
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

89673:TRAM2
gene id: 89673:TRAM2
uniprot id: A0A6J2LH34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

89673:IRF2
gene id: 89673:IRF2
uniprot id: A0A6J2MR69
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:BLOC1S5
gene id: 89673:BLOC1S5
uniprot id: A0A6J2LSZ4
names: Similarity
messages: Belongs to the BLOC1S5 family.

89673:FGF4
gene id: 89673:FGF4
uniprot id: A0A6J2M575
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

89673:LRP8
gene id: 89673:LRP8
uniprot id: A0A7E6DS12
uniprot id: A0A7E6DS18
uniprot id: A0A7E6DS25
uniprot id: A0A7E6DS35
uniprot id: A0A7E6DS42
uniprot id: A0A7E6DS49
uniprot id: A0A7E6DSP0
uniprot id: A0A7E6DSP5
uniprot id: A0A7E6DSQ1
uniprot id: A0A7E6DST6
uniprot id: A0A7E6DSU3
uniprot id: A0A7E6DSV0
uniprot id: A0A7E6DT74
uniprot id: A0A7E6DT79
uniprot id: A0A7E6DT84
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:DBNDD2
gene id: 89673:DBNDD2
uniprot id: A0A6J2MKH3
names: Similarity
messages: Belongs to the dysbindin family.

89673:HEXIM2
gene id: 89673:HEXIM2
uniprot id: A0A7E6EFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

89673:POMC
gene id: 89673:POMC
uniprot id: A0A6J2M243
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes.
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Endogenous orexigenic opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

89673:TMCC2
gene id: 89673:TMCC2
uniprot id: A0A6J2N427
uniprot id: A0A6J2N442
uniprot id: A0A6J2N8R5
uniprot id: A0A6J2N9I8
uniprot id: A0A7E6D013
names: Similarity
messages: Belongs to the TEX28 family.

89673:HOXA2
gene id: 89673:HOXA2
uniprot id: A0A6J2MVI9
names: Subcellular Location Annotation
messages: Nucleus

89673:GFRA2
gene id: 89673:GFRA2
uniprot id: A0A6J2MEN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

89673:GNA12
gene id: 89673:GNA12
uniprot id: A0A6J2MU52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

89673:EIF2B4
gene id: 89673:EIF2B4
uniprot id: A0A6J2LY26
uniprot id: A0A6J2LZ57
uniprot id: A0A6J2M016
uniprot id: A0A6J2M336
uniprot id: A0A6J2M3J3
uniprot id: A0A7E6DY50
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

89673:NR0B1
gene id: 89673:NR0B1
uniprot id: A0A6J2MFQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency.

89673:GLA
gene id: 89673:GLA
uniprot id: A0A6J2MF32
uniprot id: A0A7E6D0C8
uniprot id: A0A7E6D0J7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

89673:TAS2R16
gene id: 89673:TAS2R16
uniprot id: A0A6J2MVY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:TRPC6
gene id: 89673:TRPC6
uniprot id: A0A6J2M1A5
uniprot id: A0A7E6DZC4
names: Subcellular Location Annotation
messages: Membrane

89673:IL21
gene id: 89673:IL21
uniprot id: A0A6J2M611
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

89673:CAPN9
gene id: 89673:CAPN9
uniprot id: A0A6J2N5F1
names: Similarity
messages: Belongs to the peptidase C2 family.

89673:PEX13
gene id: 89673:PEX13
uniprot id: A0A6J2LVA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

89673:PCBD2
gene id: 89673:PCBD2
uniprot id: A0A6J2N3R8
uniprot id: A0A7E6CS95
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

89673:CDH19
gene id: 89673:CDH19
uniprot id: A0A6J2MR88
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:LMBR1
gene id: 89673:LMBR1
uniprot id: A0A6J2MPU5
uniprot id: A0A7E6CJ56
uniprot id: A0A7E6CJA2
names: Similarity
messages: Belongs to the LIMR family.

89673:TMPRSS6
gene id: 89673:TMPRSS6
uniprot id: A0A6J2NF70
uniprot id: A0A7E6D869
uniprot id: A0A7E6DB35
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:NCAPH
gene id: 89673:NCAPH
uniprot id: A0A6J2LZX1
uniprot id: A0A7E6DYG1
uniprot id: A0A7E6DYV4
uniprot id: A0A7E6DZQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

89673:GLE1
gene id: 89673:GLE1
uniprot id: A0A6J2M5V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

89673:FPGS
gene id: 89673:FPGS
uniprot id: A0A6J2LXH8
uniprot id: A0A7E6DGK8
uniprot id: A0A7E6DGQ3
names: Cofactor
names: Function
names: Similarity
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.

89673:TNFRSF11A
gene id: 89673:TNFRSF11A
uniprot id: A0A6J2MQE4
uniprot id: A0A7E6CGR2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:COG2
gene id: 89673:COG2
uniprot id: A0A6J2N569
uniprot id: A0A7E6CYC4
names: Similarity
messages: Belongs to the COG2 family.

89673:LOC114494076
gene id: 89673:LOC114494076
uniprot id: A0A7E6DQ19
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

89673:DDIT3
gene id: 89673:DDIT3
uniprot id: A0A6J2NB82
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Cytoplasm
messages: Heterodimer.
messages: Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. Negatively regulates; expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG). Inhibits the canonical Wnt signaling pathway by binding to TCF7L2/TCF4, impairing its DNA-binding properties and repressing its transcriptional activity. Plays a regulatory role in the inflammatory response through the induction of caspase-11 (CASP4/CASP11) which induces the activation of caspase-1 (CASP1) and both these caspases increase the activation of pro-IL1B to mature IL1B which is involved in the inflammatory response.
messages: Nucleus
messages: Phosphorylation at serine residues by MAPK14 enhances its transcriptional activation activity while phosphorylation at serine residues by CK2 inhibits its transcriptional activation activity.
messages: Ubiquitinated, leading to its degradation by the proteasome.

89673:DGLUCY
gene id: 89673:DGLUCY
uniprot id: A0A6J2L8Q3
uniprot id: A0A7E6CQ26
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

89673:ZC2HC1C
gene id: 89673:ZC2HC1C
uniprot id: A0A6J2L7K9
names: Similarity
messages: Belongs to the ZC2HC1 family.

89673:LOC114507468
gene id: 89673:LOC114507468
uniprot id: A0A6J2MNH3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:RSBN1L
gene id: 89673:RSBN1L
uniprot id: A0A6J2MLZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

89673:PAX5
gene id: 89673:PAX5
uniprot id: A0A6J2LW98
uniprot id: A0A7E6DFK9
uniprot id: A0A7E6DFR5
names: Subcellular Location Annotation
messages: Nucleus

89673:SAE1
gene id: 89673:SAE1
uniprot id: A0A6J2N0H2
uniprot id: A0A7E6CQH4
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

89673:C3H16orf91
gene id: 89673:C3H16orf91
uniprot id: A0A6J2M5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCSMST1 family.
messages: Membrane

89673:TACC3
gene id: 89673:TACC3
uniprot id: A0A6J2KW83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

89673:PPFIBP2
gene id: 89673:PPFIBP2
uniprot id: A0A6J2LSU2
uniprot id: A0A6J2LX28
uniprot id: A0A7E6E063
uniprot id: A0A7E6E092
uniprot id: A0A7E6E096
uniprot id: A0A7E6E0M9
uniprot id: A0A7E6E1A1
uniprot id: A0A7E6E1A7
uniprot id: A0A7E6E1D3
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

89673:MAML2
gene id: 89673:MAML2
uniprot id: A0A6J2LWY8
uniprot id: A0A7E6E099
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

89673:AMD1
gene id: 89673:AMD1
uniprot id: A0A6J2LF67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
messages: Heterotetramer of two alpha and two beta chains.

89673:SUSD3
gene id: 89673:SUSD3
uniprot id: A0A7E6D7R0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SLC25A10
gene id: 89673:SLC25A10
uniprot id: A0A6J2MBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:SESN2
gene id: 89673:SESN2
uniprot id: A0A6J2LQ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

89673:DGKD
gene id: 89673:DGKD
uniprot id: A0A6J2LJ91
uniprot id: A0A7E6DHU1
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

89673:LOC114499249
gene id: 89673:LOC114499249
uniprot id: A0A6J2LZ29
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

89673:PGAP2
gene id: 89673:PGAP2
uniprot id: A0A6J2LQS5
uniprot id: A0A6J2LS13
uniprot id: A0A6J2LVX1
uniprot id: A0A6J2LW85
uniprot id: A0A7E6E008
uniprot id: A0A7E6E0G9
uniprot id: A0A7E6E0H3
uniprot id: A0A7E6E138
uniprot id: A0A7E6E143
uniprot id: A0A7E6E160
uniprot id: A0A7E6E166
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PGAP2 family.
messages: Interacts with PGAP2IP.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

89673:ANG
gene id: 89673:ANG
uniprot id: A0A6J2L356
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

89673:LOC114503925
gene id: 89673:LOC114503925
uniprot id: A0A7E6EFL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LCOR
gene id: 89673:LCOR
uniprot id: A0A6J2LMM5
names: Subcellular Location Annotation
messages: Nucleus

89673:XPO4
gene id: 89673:XPO4
uniprot id: A0A6J2NCJ9
uniprot id: A0A7E6D4U4
uniprot id: A0A7E6D7N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Nucleus

89673:F2
gene id: 89673:F2
uniprot id: A0A6J2M2F3
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

89673:CCN6
gene id: 89673:CCN6
uniprot id: A0A6J2LKL6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:LMNA
gene id: 89673:LMNA
uniprot id: A0A6J2KWF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

89673:F13B
gene id: 89673:F13B
uniprot id: A0A6J2NAI9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114511223
gene id: 89673:LOC114511223
uniprot id: A0A6J2N1J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

89673:XPO5
gene id: 89673:XPO5
uniprot id: A0A7E6DLL6
uniprot id: A0A7E6DLZ7
names: Subcellular Location Annotation
messages: Cytoplasm

89673:LOC114494413
gene id: 89673:LOC114494413
uniprot id: A0A6J2LEA8
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse
messages: axon
messages: dendrite

89673:CD200
gene id: 89673:CD200
uniprot id: A0A6J2KYM3
uniprot id: A0A6J2L3T6
uniprot id: A0A7E6D447
uniprot id: A0A7E6D6Q6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:TNNI3
gene id: 89673:TNNI3
uniprot id: A0A6J2N4Z4
names: Function
names: Similarity
messages: Belongs to the troponin I family.
messages: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

89673:ADAMTS16
gene id: 89673:ADAMTS16
uniprot id: A0A6J2M202
uniprot id: A0A7E6DB70
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:LOC114497346
gene id: 89673:LOC114497346
uniprot id: A0A6J2LSI9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

89673:LOC114495412
gene id: 89673:LOC114495412
uniprot id: A0A7E6DH90
names: Similarity
messages: Belongs to the SUI1 family.

89673:MAPK8
gene id: 89673:MAPK8
uniprot id: A0A6J2LI68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

89673:HNRNPF
gene id: 89673:HNRNPF
uniprot id: A0A6J2LMD5
names: Subcellular Location Annotation
messages: nucleoplasm

89673:LOC114496656
gene id: 89673:LOC114496656
uniprot id: A0A6J2LQ27
uniprot id: A0A7E6DRJ8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

89673:TACC1
gene id: 89673:TACC1
uniprot id: A0A6J2MTK3
uniprot id: A0A6J2MTL0
uniprot id: A0A6J2MTL5
uniprot id: A0A6J2MY45
uniprot id: A0A6J2MY49
uniprot id: A0A6J2MYK6
uniprot id: A0A6J2MYL2
uniprot id: A0A7E6CKN5
uniprot id: A0A7E6CKN9
uniprot id: A0A7E6CMS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

89673:CMBL
gene id: 89673:CMBL
uniprot id: A0A6J2N232
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

89673:CEP44
gene id: 89673:CEP44
uniprot id: A0A6J2MII4
uniprot id: A0A7E6E8D9
uniprot id: A0A7E6EA01
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

89673:TCF7L1
gene id: 89673:TCF7L1
uniprot id: A0A6J2M0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

89673:TMEM135
gene id: 89673:TMEM135
uniprot id: A0A6J2LWT6
uniprot id: A0A7E6E0F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM135 family.
messages: Membrane
messages: Peroxisome membrane

89673:OTOGL
gene id: 89673:OTOGL
uniprot id: A0A7E6D670
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114500799
gene id: 89673:LOC114500799
uniprot id: A0A6J2M543
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC118497828
gene id: 89673:LOC118497828
uniprot id: A0A7E6CRE7
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

89673:LOC114491360
gene id: 89673:LOC114491360
uniprot id: A0A7E6E2W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

89673:PLET1
gene id: 89673:PLET1
uniprot id: A0A6J2LUF5
names: Function
messages: Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.

89673:ACAD8
gene id: 89673:ACAD8
uniprot id: A0A6J2MVV5
uniprot id: A0A7E6CTS3
uniprot id: A0A7E6CTT8
uniprot id: A0A7E6CUA0
uniprot id: A0A7E6CUI7
uniprot id: A0A7E6CWL5
uniprot id: A0A7E6CWM0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

89673:LOC114510842
gene id: 89673:LOC114510842
uniprot id: A0A6J2N4H4
names: Similarity
messages: Belongs to the MHC class I family.

89673:HMGB2
gene id: 89673:HMGB2
uniprot id: A0A6J2MA32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

89673:MACF1
gene id: 89673:MACF1
uniprot id: A0A7E6DXA9
names: Subcellular Location Annotation
messages: cytoskeleton

89673:SMAD3
gene id: 89673:SMAD3
uniprot id: A0A6J2L502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

89673:LOC114501916
gene id: 89673:LOC114501916
uniprot id: A0A7E6E6B8
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

89673:LOC114490194
gene id: 89673:LOC114490194
uniprot id: A0A6J2KWY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114500778
gene id: 89673:LOC114500778
uniprot id: A0A7E6E546
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:NDRG3
gene id: 89673:NDRG3
uniprot id: A0A6J2ML52
uniprot id: A0A6J2MQE9
names: Similarity
messages: Belongs to the NDRG family.

89673:ICAM5
gene id: 89673:ICAM5
uniprot id: A0A6J2M8R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

89673:SCN9A
gene id: 89673:SCN9A
uniprot id: A0A6J2LEB9
uniprot id: A0A6J2LJ01
uniprot id: A0A7E6DJK2
uniprot id: A0A7E6DJT1
uniprot id: A0A7E6DJT7
uniprot id: A0A7E6DJZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

89673:LOC114499041
gene id: 89673:LOC114499041
uniprot id: A0A6J2LSS5
names: Subcellular Location Annotation
messages: Membrane

89673:CDC42EP3
gene id: 89673:CDC42EP3
uniprot id: A0A7E6DYF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

89673:LOC114506062
gene id: 89673:LOC114506062
uniprot id: A0A6J2MIS6
names: Similarity
messages: Belongs to the pro/parathymosin family.

89673:SYCP2
gene id: 89673:SYCP2
uniprot id: A0A7E6CEJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYCP2 family.
messages: Nucleus

89673:DMBT1
gene id: 89673:DMBT1
uniprot id: A0A7E6DVQ6
names: Caution
names: Similarity
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:PBRM1
gene id: 89673:PBRM1
uniprot id: A0A7E6E6Z3
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114505241
gene id: 89673:LOC114505241
uniprot id: A0A6J2ML91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-5 subfamily.
messages: Nucleus

89673:CDX1
gene id: 89673:CDX1
uniprot id: A0A6J2MWK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

89673:STK3
gene id: 89673:STK3
uniprot id: A0A6J2NC50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

89673:GALNT2
gene id: 89673:GALNT2
uniprot id: A0A6J2N5N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:RAB21
gene id: 89673:RAB21
uniprot id: A0A6J2NCP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Cytoplasmic vesicle membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: neuron projection
messages: trans-Golgi network

89673:CNR1
gene id: 89673:CNR1
uniprot id: A0A6J2LFX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Signaling typically involves reduction in cyclic AMP.
messages: Interacts (via C-terminus) with CNRIP1.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

89673:SERPINE1
gene id: 89673:SERPINE1
uniprot id: A0A6J2LIV3
names: Similarity
messages: Belongs to the serpin family.

89673:LOC114508725
gene id: 89673:LOC114508725
uniprot id: A0A6J2MXL3
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:RABAC1
gene id: 89673:RABAC1
uniprot id: A0A6J2N178
uniprot id: A0A7E6CPC3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC118499395
gene id: 89673:LOC118499395
uniprot id: A0A7E6DAN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

89673:UST
gene id: 89673:UST
uniprot id: A0A6J2LK71
uniprot id: A0A7E6DNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

89673:LOC114500433
gene id: 89673:LOC114500433
uniprot id: A0A6J2LYV7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:IWS1
gene id: 89673:IWS1
uniprot id: A0A6J2LCE2
uniprot id: A0A6J2LF75
uniprot id: A0A7E6DKH3
uniprot id: A0A7E6DKS3
uniprot id: A0A7E6DKU2
uniprot id: A0A7E6DL45
names: Subcellular Location Annotation
messages: Nucleus

89673:KIN
gene id: 89673:KIN
uniprot id: A0A6J2LCH6
uniprot id: A0A7E6DN69
uniprot id: A0A7E6DNA5
names: Similarity
messages: Belongs to the KIN17 family.

89673:CDH6
gene id: 89673:CDH6
uniprot id: A0A6J2MZZ1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:TARBP2
gene id: 89673:TARBP2
uniprot id: A0A6J2N8U8
uniprot id: A0A7E6D6G8
uniprot id: A0A7E6D724
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC. Interacts with EIF2AK2/PKR and inhibits its protein kinase activity. Interacts with DHX9 and PRKRA. Interacts with DICER1, AGO2, MOV10, EIF6 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC).
messages: perinuclear region

89673:FUCA2
gene id: 89673:FUCA2
uniprot id: A0A6J2LEJ5
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

89673:TMED9
gene id: 89673:TMED9
uniprot id: A0A6J2N2E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:GAS6
gene id: 89673:GAS6
uniprot id: A0A6J2MXH7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114502314
gene id: 89673:LOC114502314
uniprot id: A0A6J2M618
uniprot id: A0A7E6E947
uniprot id: A0A7E6EAR0
uniprot id: A0A7E6EB57
names: Subcellular Location Annotation
messages: Nucleus

89673:ZNF592
gene id: 89673:ZNF592
uniprot id: A0A6J2KSR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

89673:ARGFX
gene id: 89673:ARGFX
uniprot id: A0A6J2KST1
names: Subcellular Location Annotation
messages: Nucleus

89673:MFSD10
gene id: 89673:MFSD10
uniprot id: A0A6J2KZW4
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114506103
gene id: 89673:LOC114506103
uniprot id: A0A7E6CEC4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

89673:IL1RL1
gene id: 89673:IL1RL1
uniprot id: A0A6J2LXY4
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

89673:EPOR
gene id: 89673:EPOR
uniprot id: A0A6J2MA55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Forms homodimers on EPO stimulation.
messages: Membrane
messages: Receptor for erythropoietin.

89673:PHF10
gene id: 89673:PHF10
uniprot id: A0A6J2KX56
uniprot id: A0A7E6DNY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

89673:MRPL14
gene id: 89673:MRPL14
uniprot id: A0A6J2LF87
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

89673:FAM131A
gene id: 89673:FAM131A
uniprot id: A0A6J2KYD3
uniprot id: A0A6J2KYY9
uniprot id: A0A6J2L2C0
names: Similarity
messages: Belongs to the FAM131 family.

89673:LOC114505290
gene id: 89673:LOC114505290
uniprot id: A0A6J2MG00
uniprot id: A0A6J2MM64
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:ECI1
gene id: 89673:ECI1
uniprot id: A0A6J2LRP1
uniprot id: A0A7E6DC78
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

89673:LOC114490205
gene id: 89673:LOC114490205
uniprot id: A0A6J2KWY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114506226
gene id: 89673:LOC114506226
uniprot id: A0A7E6D9Q6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.

89673:LOC114499075
gene id: 89673:LOC114499075
uniprot id: A0A6J2LXX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TBXA2R
gene id: 89673:TBXA2R
uniprot id: A0A6J2M9V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:INHBB
gene id: 89673:INHBB
uniprot id: A0A6J2NBW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

89673:HOPX
gene id: 89673:HOPX
uniprot id: A0A6J2L6Y6
names: Subcellular Location Annotation
messages: Nucleus

89673:EEF1A2
gene id: 89673:EEF1A2
uniprot id: A0A6J2MMP1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

89673:LOC114506255
gene id: 89673:LOC114506255
uniprot id: A0A6J2MP04
names: Similarity
messages: Belongs to the copine family.

89673:NOP58
gene id: 89673:NOP58
uniprot id: A0A6J2LD27
uniprot id: A0A6J2LHS6
uniprot id: A0A7E6DIW3
uniprot id: A0A7E6DJ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

89673:BIRC7
gene id: 89673:BIRC7
uniprot id: A0A7E6CG11
uniprot id: A0A7E6CGA8
uniprot id: A0A7E6CGI9
uniprot id: A0A7E6CI52
names: Similarity
messages: Belongs to the IAP family.

89673:LOC114498950
gene id: 89673:LOC114498950
uniprot id: A0A6J2LTT9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TPI1
gene id: 89673:TPI1
uniprot id: A0A6J2NF89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

89673:LOC114499150
gene id: 89673:LOC114499150
uniprot id: A0A6J2LY29
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

89673:RELT
gene id: 89673:RELT
uniprot id: A0A7E6E0C0
uniprot id: A0A7E6E108
names: Similarity
messages: Belongs to the RELT family.

89673:SERINC5
gene id: 89673:SERINC5
uniprot id: A0A6J2M8M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Cell membrane
messages: Membrane

89673:MTERF1
gene id: 89673:MTERF1
uniprot id: A0A6J2MPA3
names: Similarity
messages: Belongs to the mTERF family.

89673:OTC
gene id: 89673:OTC
uniprot id: A0A6J2MGN7
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

89673:MAN2B2
gene id: 89673:MAN2B2
uniprot id: A0A6J2L590
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

89673:TRABD2A
gene id: 89673:TRABD2A
uniprot id: A0A7E6E492
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

89673:RP1
gene id: 89673:RP1
uniprot id: A0A7E6E6I1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:KCNJ4
gene id: 89673:KCNJ4
uniprot id: A0A6J2N9I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

89673:MCRIP2
gene id: 89673:MCRIP2
uniprot id: A0A6J2N556
uniprot id: A0A7E6DCW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

89673:CD44
gene id: 89673:CD44
uniprot id: A0A6J2M1K4
uniprot id: A0A6J2M528
uniprot id: A0A7E6E0T4
uniprot id: A0A7E6E0T7
uniprot id: A0A7E6E0U1
uniprot id: A0A7E6E173
uniprot id: A0A7E6E178
uniprot id: A0A7E6E183
uniprot id: A0A7E6E188
uniprot id: A0A7E6E1D5
uniprot id: A0A7E6E1E0
uniprot id: A0A7E6E1E6
uniprot id: A0A7E6E1F1
uniprot id: A0A7E6E233
uniprot id: A0A7E6E235
uniprot id: A0A7E6E239
uniprot id: A0A7E6E240
uniprot id: A0A7E6E244
uniprot id: A0A7E6E245
uniprot id: A0A7E6E249
uniprot id: A0A7E6E250
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

89673:LOC114515504
gene id: 89673:LOC114515504
uniprot id: A0A6J2NFL0
names: Similarity
messages: Belongs to the cytochrome b5 family.

89673:MYO5A
gene id: 89673:MYO5A
uniprot id: A0A6J2L958
uniprot id: A0A7E6EDQ8
uniprot id: A0A7E6EDX6
uniprot id: A0A7E6EDY1
uniprot id: A0A7E6EEQ6
uniprot id: A0A7E6EF01
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:RAB5IF
gene id: 89673:RAB5IF
uniprot id: A0A6J2MP95
names: Subcellular Location Annotation
messages: Membrane

89673:FADS3
gene id: 89673:FADS3
uniprot id: A0A6J2LWG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane

89673:SDC3
gene id: 89673:SDC3
uniprot id: A0A6J2LMT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

89673:RAG1
gene id: 89673:RAG1
uniprot id: A0A6J2M5H8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

89673:FAM160A2
gene id: 89673:FAM160A2
uniprot id: A0A6J2LZX6
uniprot id: A0A6J2M0T5
uniprot id: A0A7E6E399
uniprot id: A0A7E6E3V1
uniprot id: A0A7E6E3Y2
uniprot id: A0A7E6E4W9
names: Similarity
messages: Belongs to the FHIP family.

89673:FAM131B
gene id: 89673:FAM131B
uniprot id: A0A6J2MTV8
names: Similarity
messages: Belongs to the FAM131 family.

89673:CMAS
gene id: 89673:CMAS
uniprot id: A0A6J2N8H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
messages: Homotetramer; the active enzyme is formed by a dimer of dimers.

89673:LOC114505985
gene id: 89673:LOC114505985
uniprot id: A0A6J2MIP6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

89673:ABHD1
gene id: 89673:ABHD1
uniprot id: A0A6J2LWP2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

89673:EID3
gene id: 89673:EID3
uniprot id: A0A6J2N8R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

89673:TEKT5
gene id: 89673:TEKT5
uniprot id: A0A6J2MZQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

89673:TMEM63C
gene id: 89673:TMEM63C
uniprot id: A0A7E6CNT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

89673:ADAMTS3
gene id: 89673:ADAMTS3
uniprot id: A0A6J2LAV5
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:LOC114501818
gene id: 89673:LOC114501818
uniprot id: A0A6J2M4B8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:MCM5
gene id: 89673:MCM5
uniprot id: A0A6J2NAC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

89673:PEAR1
gene id: 89673:PEAR1
uniprot id: A0A6J2KU65
uniprot id: A0A7E6CWY2
uniprot id: A0A7E6CXC1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114504133
gene id: 89673:LOC114504133
uniprot id: A0A6J2MI08
names: Similarity
messages: Belongs to the KRTAP type 3 family.

89673:LOC114515364
gene id: 89673:LOC114515364
uniprot id: A0A7E6EDP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ACBD5
gene id: 89673:ACBD5
uniprot id: A0A6J2L2I6
uniprot id: A0A6J2L450
uniprot id: A0A6J2L7H0
uniprot id: A0A7E6DI72
uniprot id: A0A7E6DI88
uniprot id: A0A7E6DIF9
uniprot id: A0A7E6DIH7
uniprot id: A0A7E6DIJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane
messages: Peroxisome membrane

89673:SLC5A12
gene id: 89673:SLC5A12
uniprot id: A0A6J2LYS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

89673:LDLRAD4
gene id: 89673:LDLRAD4
uniprot id: A0A6J2MMN4
uniprot id: A0A7E6CE30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

89673:DOK5
gene id: 89673:DOK5
uniprot id: A0A6J2MIK9
uniprot id: A0A7E6CG41
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

89673:LOC114508181
gene id: 89673:LOC114508181
uniprot id: A0A6J2MVW4
uniprot id: A0A7E6CJ62
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:CPXM1
gene id: 89673:CPXM1
uniprot id: A0A6J2MPJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

89673:LOC114500429
gene id: 89673:LOC114500429
uniprot id: A0A6J2M4E0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NDUFA13
gene id: 89673:NDUFA13
uniprot id: A0A6J2MBQ1
uniprot id: A0A7E6EBT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

89673:ITM2A
gene id: 89673:ITM2A
uniprot id: A0A6J2MHA3
uniprot id: A0A6J2MLK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

89673:LOC114498973
gene id: 89673:LOC114498973
uniprot id: A0A7E6E3K3
names: Similarity
messages: Belongs to the nucleobindin family.

89673:TRIM32
gene id: 89673:TRIM32
uniprot id: A0A6J2LCU7
names: Similarity
messages: Belongs to the TRIM/RBCC family.

89673:TDO2
gene id: 89673:TDO2
uniprot id: A0A6J2M9S2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RIPPLY3
gene id: 89673:RIPPLY3
uniprot id: A0A6J2L4D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

89673:IL19
gene id: 89673:IL19
uniprot id: A0A6J2N9F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

89673:UVSSA
gene id: 89673:UVSSA
uniprot id: A0A6J2KW74
uniprot id: A0A7E6D688
names: Similarity
messages: Belongs to the UVSSA family.

89673:MYCBP2
gene id: 89673:MYCBP2
uniprot id: A0A6J2MPS6
uniprot id: A0A7E6CJR1
uniprot id: A0A7E6CJR7
uniprot id: A0A7E6CJR8
uniprot id: A0A7E6CJS4
uniprot id: A0A7E6CJT4
uniprot id: A0A7E6CJT6
uniprot id: A0A7E6CJU1
uniprot id: A0A7E6CJU7
uniprot id: A0A7E6CJV6
uniprot id: A0A7E6CJW7
uniprot id: A0A7E6CLT3
uniprot id: A0A7E6CLU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RING-Cys relay (RCR) family.
messages: axon

89673:ZDHHC22
gene id: 89673:ZDHHC22
uniprot id: A0A6J2LE26
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:LMNB2
gene id: 89673:LMNB2
uniprot id: A0A6J2MBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

89673:XRCC4
gene id: 89673:XRCC4
uniprot id: A0A6J2N1L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

89673:LOC114499797
gene id: 89673:LOC114499797
uniprot id: A0A6J2LWF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:GKAP1
gene id: 89673:GKAP1
uniprot id: A0A6J2MMA5
uniprot id: A0A7E6DF64
uniprot id: A0A7E6DF96
uniprot id: A0A7E6DF97
uniprot id: A0A7E6DFB2
names: Similarity
messages: Belongs to the GKAP1 family.

89673:NUDT21
gene id: 89673:NUDT21
uniprot id: A0A6J2KU64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

89673:EIF3K
gene id: 89673:EIF3K
uniprot id: A0A6J2N0D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with CCND3, but not with CCND1 and CCND2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Nucleus

89673:MEOX1
gene id: 89673:MEOX1
uniprot id: A0A6J2MBX3
names: Subcellular Location Annotation
messages: Nucleus

89673:KLC4
gene id: 89673:KLC4
uniprot id: A0A6J2LD98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

89673:LYRM9
gene id: 89673:LYRM9
uniprot id: A0A6J2MCN1
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

89673:LIG3
gene id: 89673:LIG3
uniprot id: A0A6J2MDJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

89673:UBA52
gene id: 89673:UBA52
uniprot id: A0A6J2MB84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Component of the 60S subunit of the ribosome. Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus
messages: Ribosomal protein L40 is part of the 60S ribosomal subunit. Interacts with UBQLN1 (via UBA domain).

89673:RFC5
gene id: 89673:RFC5
uniprot id: A0A6J2N3U8
names: Similarity
messages: Belongs to the activator 1 small subunits family.

89673:GLRB
gene id: 89673:GLRB
uniprot id: A0A6J2MBY2
uniprot id: A0A7E6E924
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114500439
gene id: 89673:LOC114500439
uniprot id: A0A6J2M4F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MED16
gene id: 89673:MED16
uniprot id: A0A6J2MC50
uniprot id: A0A7E6EA82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

89673:NDUFAF1
gene id: 89673:NDUFAF1
uniprot id: A0A6J2L9Y2
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

89673:HTRA2
gene id: 89673:HTRA2
uniprot id: A0A6J2M5V8
names: Similarity
messages: Belongs to the peptidase S1C family.

89673:NUPR2
gene id: 89673:NUPR2
uniprot id: A0A6J2MLK5
names: Similarity
messages: Belongs to the NUPR family.

89673:CHPF2
gene id: 89673:CHPF2
uniprot id: A0A6J2MQX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

89673:MTG2
gene id: 89673:MTG2
uniprot id: A0A6J2MM27
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

89673:FAM53B
gene id: 89673:FAM53B
uniprot id: A0A6J2LPI8
names: Similarity
messages: Belongs to the FAM53 family.

89673:MRPL13
gene id: 89673:MRPL13
uniprot id: A0A6J2NB66
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

89673:CPLANE2
gene id: 89673:CPLANE2
uniprot id: A0A6J2LPB3
uniprot id: A0A7E6DPZ2
uniprot id: A0A7E6DQ14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
messages: cilium basal body

89673:PLXND1
gene id: 89673:PLXND1
uniprot id: A0A6J2M6D1
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:DMRTC2
gene id: 89673:DMRTC2
uniprot id: A0A6J2N2T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

89673:LOC114497373
gene id: 89673:LOC114497373
uniprot id: A0A6J2LSM4
names: Similarity
messages: Belongs to the histone H3 family.

89673:ATP5F1B
gene id: 89673:ATP5F1B
uniprot id: A0A6J2N715
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

89673:TOMM20
gene id: 89673:TOMM20
uniprot id: A0A6J2N5N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

89673:LOC114510242
gene id: 89673:LOC114510242
uniprot id: A0A6J2N397
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:YPEL4
gene id: 89673:YPEL4
uniprot id: A0A6J2M1E0
names: Similarity
messages: Belongs to the yippee family.

89673:MS4A2
gene id: 89673:MS4A2
uniprot id: A0A6J2M0A6
names: Similarity
messages: Belongs to the MS4A family.

89673:SEPTIN2
gene id: 89673:SEPTIN2
uniprot id: A0A6J2LBC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium membrane
messages: flagellum
messages: spindle

89673:XPNPEP2
gene id: 89673:XPNPEP2
uniprot id: A0A6J2MHR5
names: Similarity
messages: Belongs to the peptidase M24B family.

89673:PLA2G6
gene id: 89673:PLA2G6
uniprot id: A0A7E6D8F4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RPS23
gene id: 89673:RPS23
uniprot id: A0A6J2LRV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Component of the 40S small ribosomal subunit.
messages: Rough endoplasmic reticulum

89673:ADGRA1
gene id: 89673:ADGRA1
uniprot id: A0A7E6DW19
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114500377
gene id: 89673:LOC114500377
uniprot id: A0A6J2M3P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC118500232
gene id: 89673:LOC118500232
uniprot id: A0A7E6DM52
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:HSF5
gene id: 89673:HSF5
uniprot id: A0A6J2MGB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

89673:WDFY2
gene id: 89673:WDFY2
uniprot id: A0A6J2MX09
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

89673:ANAPC1
gene id: 89673:ANAPC1
uniprot id: A0A6J2LTU6
uniprot id: A0A7E6DY88
names: Similarity
messages: Belongs to the APC1 family.

89673:DTX2
gene id: 89673:DTX2
uniprot id: A0A6J2MCX5
uniprot id: A0A6J2MFS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

89673:CXCL6
gene id: 89673:CXCL6
uniprot id: A0A6J2L3F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

89673:LOC114513663
gene id: 89673:LOC114513663
uniprot id: A0A6J2NFB6
names: Function
names: Similarity
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.

89673:FAT4
gene id: 89673:FAT4
uniprot id: A0A6J2MBE5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ATP6AP2
gene id: 89673:ATP6AP2
uniprot id: A0A6J2MGQ2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

89673:HTR1D
gene id: 89673:HTR1D
uniprot id: A0A6J2LTD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1B.
messages: Membrane

89673:GUSB
gene id: 89673:GUSB
uniprot id: A0A6J2MIY7
uniprot id: A0A6J2MMI2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homotetramer.
messages: Inhibited by L-aspartic acid.
messages: Lysosome
messages: Plays an important role in the degradation of dermatan and keratan sulfates.

89673:SCT
gene id: 89673:SCT
uniprot id: A0A6J2LY70
names: Similarity
messages: Belongs to the glucagon family.

89673:LOC114512171
gene id: 89673:LOC114512171
uniprot id: A0A6J2N332
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

89673:KIF24
gene id: 89673:KIF24
uniprot id: A0A6J2N828
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:NEK6
gene id: 89673:NEK6
uniprot id: A0A6J2M4E1
uniprot id: A0A7E6DGB0
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:FAM98C
gene id: 89673:FAM98C
uniprot id: A0A6J2N6G8
uniprot id: A0A7E6CR39
uniprot id: A0A7E6CR62
uniprot id: A0A7E6CRH6
uniprot id: A0A7E6CRJ7
uniprot id: A0A7E6CTS8
names: Similarity
messages: Belongs to the FAM98 family.

89673:LOC114506582
gene id: 89673:LOC114506582
uniprot id: A0A7E6CIG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

89673:GABRG3
gene id: 89673:GABRG3
uniprot id: A0A6J2KVN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:TPRKB
gene id: 89673:TPRKB
uniprot id: A0A7E6DZ76
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

89673:CHADL
gene id: 89673:CHADL
uniprot id: A0A7E6DBC2
names: Similarity
messages: Belongs to the Toll-like receptor family.

89673:KCNQ3
gene id: 89673:KCNQ3
uniprot id: A0A6J2NHY4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:KCNG3
gene id: 89673:KCNG3
uniprot id: A0A6J2LZG6
uniprot id: A0A6J2M0Q6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:LOC114500094
gene id: 89673:LOC114500094
uniprot id: A0A6J2LYS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PRPSAP2
gene id: 89673:PRPSAP2
uniprot id: A0A6J2NJ33
uniprot id: A0A7E6EBQ5
uniprot id: A0A7E6ECU4
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

89673:CCNDBP1
gene id: 89673:CCNDBP1
uniprot id: A0A6J2LB38
names: Similarity
names: Subunit
messages: Belongs to the CCNDBP1 family.
messages: Interacts with CCND1 and GRAP2. May also interact with COPS5, RPLP0, SIRT6, SYF2 and TCF3.

89673:LOC114495032
gene id: 89673:LOC114495032
uniprot id: A0A6J2LE67
names: Subcellular Location Annotation
messages: Cytoplasm

89673:LOC114505252
gene id: 89673:LOC114505252
uniprot id: A0A7E6CZS1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:EARS2
gene id: 89673:EARS2
uniprot id: A0A7E6DE25
uniprot id: A0A7E6DE32
uniprot id: A0A7E6DE36
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

89673:MEF2C
gene id: 89673:MEF2C
uniprot id: A0A6J2MZB1
uniprot id: A0A6J2MZD2
uniprot id: A0A6J2N3Z8
uniprot id: A0A6J2N4N5
uniprot id: A0A7E6DAP5
uniprot id: A0A7E6DAT1
uniprot id: A0A7E6DB36
uniprot id: A0A7E6DDA0
names: Subcellular Location Annotation
messages: Nucleus

89673:LDHD
gene id: 89673:LDHD
uniprot id: A0A6J2KQX1
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

89673:LOC114504791
gene id: 89673:LOC114504791
uniprot id: A0A7E6CZC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: centrosome
messages: spindle pole

89673:POP5
gene id: 89673:POP5
uniprot id: A0A7E6CTU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

89673:MTFR1
gene id: 89673:MTFR1
uniprot id: A0A6J2NCK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

89673:LOC114499048
gene id: 89673:LOC114499048
uniprot id: A0A6J2LYA7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ACVR1B
gene id: 89673:ACVR1B
uniprot id: A0A6J2N592
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

89673:HS6ST2
gene id: 89673:HS6ST2
uniprot id: A0A7E6D0Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

89673:LOC114503445
gene id: 89673:LOC114503445
uniprot id: A0A6J2M9X1
uniprot id: A0A6J2MC51
uniprot id: A0A7E6EBQ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:CCKBR
gene id: 89673:CCKBR
uniprot id: A0A6J2M002
uniprot id: A0A6J2M0V7
uniprot id: A0A6J2M3U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:ZDHHC20
gene id: 89673:ZDHHC20
uniprot id: A0A6J2N9N0
uniprot id: A0A7E6D4U9
uniprot id: A0A7E6D4X9
uniprot id: A0A7E6D4Y3
uniprot id: A0A7E6D507
uniprot id: A0A7E6D7N9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:DNAH5
gene id: 89673:DNAH5
uniprot id: A0A7E6DAB6
uniprot id: A0A7E6DB40
names: Similarity
messages: Belongs to the dynein heavy chain family.

89673:IDH2
gene id: 89673:IDH2
uniprot id: A0A6J2KRU2
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

89673:LOC114494333
gene id: 89673:LOC114494333
uniprot id: A0A6J2LGG9
uniprot id: A0A7E6DIA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

89673:GPR183
gene id: 89673:GPR183
uniprot id: A0A6J2MPU8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:TUBGCP3
gene id: 89673:TUBGCP3
uniprot id: A0A6J2MRR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

89673:PKD1L1
gene id: 89673:PKD1L1
uniprot id: A0A7E6CHG1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:ALKBH8
gene id: 89673:ALKBH8
uniprot id: A0A6J2M4E9
uniprot id: A0A7E6DZ67
uniprot id: A0A7E6DZN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkB family.
messages: Cytoplasm

89673:EBF3
gene id: 89673:EBF3
uniprot id: A0A6J2LPE0
uniprot id: A0A6J2LRL7
uniprot id: A0A6J2LUU8
uniprot id: A0A6J2LUV8
uniprot id: A0A7E6DVT8
uniprot id: A0A7E6DVZ7
uniprot id: A0A7E6DW02
uniprot id: A0A7E6DWE0
uniprot id: A0A7E6DWE5
uniprot id: A0A7E6DWE9
uniprot id: A0A7E6DWS3
uniprot id: A0A7E6DWS9
uniprot id: A0A7E6DX78
uniprot id: A0A7E6DX82
uniprot id: A0A7E6DX87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

89673:USP44
gene id: 89673:USP44
uniprot id: A0A6J2NFJ1
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

89673:SMC5
gene id: 89673:SMC5
uniprot id: A0A6J2LCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Nucleus

89673:PDE11A
gene id: 89673:PDE11A
uniprot id: A0A6J2LI44
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:YWHAH
gene id: 89673:YWHAH
uniprot id: A0A6J2MUM1
names: Similarity
messages: Belongs to the 14-3-3 family.

89673:CNR2
gene id: 89673:CNR2
uniprot id: A0A6J2LR49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:LOC114512861
gene id: 89673:LOC114512861
uniprot id: A0A7E6D221
names: Similarity
messages: Belongs to the GroES chaperonin family.

89673:TMA16
gene id: 89673:TMA16
uniprot id: A0A6J2MD80
uniprot id: A0A7E6E962
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

89673:ACTL7B
gene id: 89673:ACTL7B
uniprot id: A0A6J2MWK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

89673:LOC114505971
gene id: 89673:LOC114505971
uniprot id: A0A6J2MML5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

89673:SMAD5
gene id: 89673:SMAD5
uniprot id: A0A6J2MX71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

89673:DDX1
gene id: 89673:DDX1
uniprot id: A0A6J2LVT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule

89673:OPA3
gene id: 89673:OPA3
uniprot id: A0A6J2N1Y5
uniprot id: A0A6J2N7D8
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

89673:LMNB1
gene id: 89673:LMNB1
uniprot id: A0A6J2M1H6
uniprot id: A0A7E6DDF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

89673:LOC114509904
gene id: 89673:LOC114509904
uniprot id: A0A6J2MVV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with BRAWNIN.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

89673:FBXO9
gene id: 89673:FBXO9
uniprot id: A0A6J2LD20
uniprot id: A0A6J2LGS9
names: Subcellular Location Annotation
messages: Cytoplasm

89673:LOC114503696
gene id: 89673:LOC114503696
uniprot id: A0A7E6EAF0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:AVPR1B
gene id: 89673:AVPR1B
uniprot id: A0A6J2N4M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

89673:ERGIC3
gene id: 89673:ERGIC3
uniprot id: A0A6J2MKE8
uniprot id: A0A6J2MRJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

89673:DHRS9
gene id: 89673:DHRS9
uniprot id: A0A6J2LH98
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:ARF5
gene id: 89673:ARF5
uniprot id: A0A6J2MLT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

89673:LOC114500354
gene id: 89673:LOC114500354
uniprot id: A0A6J2LYL1
uniprot id: A0A6J2M443
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114489472
gene id: 89673:LOC114489472
uniprot id: A0A6J2KYV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:RABEP1
gene id: 89673:RABEP1
uniprot id: A0A6J2NJM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

89673:LOC114515184
gene id: 89673:LOC114515184
uniprot id: A0A6J2NJM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

89673:SYK
gene id: 89673:SYK
uniprot id: A0A6J2N621
uniprot id: A0A7E6DE69
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

89673:STUM
gene id: 89673:STUM
uniprot id: A0A6J2N5R4
uniprot id: A0A6J2NAD8
names: Subcellular Location Annotation
messages: Membrane

89673:GDI2
gene id: 89673:GDI2
uniprot id: A0A6J2L130
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

89673:LOC118499773
gene id: 89673:LOC118499773
uniprot id: A0A7E6DG63
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

89673:STMN1
gene id: 89673:STMN1
uniprot id: A0A6J2LSH6
names: Similarity
messages: Belongs to the stathmin family.

89673:NPFFR1
gene id: 89673:NPFFR1
uniprot id: A0A7E6DWJ6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

89673:LOC114489394
gene id: 89673:LOC114489394
uniprot id: A0A6J2L0Q6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:NTN4
gene id: 89673:NTN4
uniprot id: A0A6J2N6J9
uniprot id: A0A7E6DAP4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TRIM54
gene id: 89673:TRIM54
uniprot id: A0A6J2M083
names: Function
names: Subcellular Location Annotation
messages: May bind and stabilize microtubules during myotubes formation.
messages: Z line

89673:PPP2CA
gene id: 89673:PPP2CA
uniprot id: A0A6J2MYU9
names: Similarity
messages: Belongs to the PPP phosphatase family.

89673:NTRK2
gene id: 89673:NTRK2
uniprot id: A0A6J2L303
uniprot id: A0A6J2L3P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

89673:DNASE1
gene id: 89673:DNASE1
uniprot id: A0A6J2LI53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNase I family.
messages: Nucleus envelope
messages: Zymogen granule

89673:LIAS
gene id: 89673:LIAS
uniprot id: A0A6J2L6M7
uniprot id: A0A7E6D8X4
uniprot id: A0A7E6D931
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

89673:UNC45A
gene id: 89673:UNC45A
uniprot id: A0A7E6CMV6
names: Subcellular Location Annotation
messages: perinuclear region

89673:G6PC3
gene id: 89673:G6PC3
uniprot id: A0A6J2M8U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

89673:TMEM177
gene id: 89673:TMEM177
uniprot id: A0A7E6DK92
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

89673:FAM91A1
gene id: 89673:FAM91A1
uniprot id: A0A6J2NB47
uniprot id: A0A7E6E7C1
names: Similarity
messages: Belongs to the FAM91 family.

89673:WT1
gene id: 89673:WT1
uniprot id: A0A7E6E0Q2
uniprot id: A0A7E6E140
uniprot id: A0A7E6E1A9
uniprot id: A0A7E6E1Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

89673:LOC114510849
gene id: 89673:LOC114510849
uniprot id: A0A7E6D9F0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

89673:TMEM87A
gene id: 89673:TMEM87A
uniprot id: A0A6J2L820
uniprot id: A0A6J2L997
uniprot id: A0A6J2LDC4
uniprot id: A0A7E6EA85
uniprot id: A0A7E6EAK8
names: Subcellular Location Annotation
messages: Membrane

89673:TACSTD2
gene id: 89673:TACSTD2
uniprot id: A0A6J2LLC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:UGT2A3
gene id: 89673:UGT2A3
uniprot id: A0A7E6DE92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

89673:LYPD6B
gene id: 89673:LYPD6B
uniprot id: A0A6J2LIC1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:GOLGA5
gene id: 89673:GOLGA5
uniprot id: A0A6J2L4V0
uniprot id: A0A7E6CQL2
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.
messages: Membrane

89673:LOC114505428
gene id: 89673:LOC114505428
uniprot id: A0A7E6D1G4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

89673:CPVL
gene id: 89673:CPVL
uniprot id: A0A6J2MQT0
names: Similarity
messages: Belongs to the peptidase S10 family.

89673:LOC114501611
gene id: 89673:LOC114501611
uniprot id: A0A6J2M3G1
names: Similarity
messages: Belongs to the transferrin family.

89673:HNRNPC
gene id: 89673:HNRNPC
uniprot id: A0A6J2KXA9
uniprot id: A0A6J2KXV8
uniprot id: A0A6J2KXW2
uniprot id: A0A7E6E4W2
uniprot id: A0A7E6E5F0
uniprot id: A0A7E6E5I5
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

89673:LOC114503640
gene id: 89673:LOC114503640
uniprot id: A0A6J2MG87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:KCNN4
gene id: 89673:KCNN4
uniprot id: A0A6J2N5I7
names: Subcellular Location Annotation
messages: Membrane

89673:BLM
gene id: 89673:BLM
uniprot id: A0A6J2KRD4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

89673:POLR3D
gene id: 89673:POLR3D
uniprot id: A0A6J2MAX8
names: Subcellular Location Annotation
messages: Nucleus

89673:SHANK2
gene id: 89673:SHANK2
uniprot id: A0A6J2KYI8
uniprot id: A0A7E6E2E0
uniprot id: A0A7E6E3W1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.
messages: Postsynaptic density

89673:PNO1
gene id: 89673:PNO1
uniprot id: A0A6J2LW06
uniprot id: A0A7E6DYI1
names: Similarity
messages: Belongs to the PNO1 family.

89673:EBF4
gene id: 89673:EBF4
uniprot id: A0A6J2MK26
uniprot id: A0A7E6CEV6
uniprot id: A0A7E6CFI7
uniprot id: A0A7E6CH27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

89673:LOC114494211
gene id: 89673:LOC114494211
uniprot id: A0A6J2LCV2
uniprot id: A0A7E6DI81
names: Similarity
messages: Belongs to the tubulin family.

89673:TRAP1
gene id: 89673:TRAP1
uniprot id: A0A6J2LFF2
names: Similarity
messages: Belongs to the heat shock protein 90 family.

89673:TUBB1
gene id: 89673:TUBB1
uniprot id: A0A6J2MIX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

89673:FUNDC1
gene id: 89673:FUNDC1
uniprot id: A0A6J2MHH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

89673:UEVLD
gene id: 89673:UEVLD
uniprot id: A0A7E6E0U5
uniprot id: A0A7E6E1S8
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

89673:MECP2
gene id: 89673:MECP2
uniprot id: A0A6J2MDT9
uniprot id: A0A6J2MFZ0
names: Function
names: Subcellular Location Annotation
messages: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
messages: Nucleus

89673:SNX30
gene id: 89673:SNX30
uniprot id: A0A6J2LVC1
names: Similarity
messages: Belongs to the sorting nexin family.

89673:EXTL1
gene id: 89673:EXTL1
uniprot id: A0A6J2LSQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114500366
gene id: 89673:LOC114500366
uniprot id: A0A7E6E186
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114507859
gene id: 89673:LOC114507859
uniprot id: A0A6J2MUZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SRP14
gene id: 89673:SRP14
uniprot id: A0A6J2L853
uniprot id: A0A7E6E8Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

89673:LOC114503584
gene id: 89673:LOC114503584
uniprot id: A0A7E6E870
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

89673:LOC114507616
gene id: 89673:LOC114507616
uniprot id: A0A6J2MTV1
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

89673:MED19
gene id: 89673:MED19
uniprot id: A0A6J2LYS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

89673:SH2B3
gene id: 89673:SH2B3
uniprot id: A0A6J2MUW5
uniprot id: A0A7E6CUU8
uniprot id: A0A7E6CUU9
uniprot id: A0A7E6CVB7
uniprot id: A0A7E6CVL6
names: Similarity
messages: Belongs to the SH2B adapter family.

89673:MAPRE3
gene id: 89673:MAPRE3
uniprot id: A0A6J2LWA2
uniprot id: A0A6J2M1T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

89673:VAMP3
gene id: 89673:VAMP3
uniprot id: A0A6J2LMY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

89673:FTH1
gene id: 89673:FTH1
uniprot id: A0A6J2M3T0
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:NPRL2
gene id: 89673:NPRL2
uniprot id: A0A6J2M121
names: Similarity
messages: Belongs to the NPR2 family.

89673:YPEL5
gene id: 89673:YPEL5
uniprot id: A0A6J2LZJ4
names: Similarity
messages: Belongs to the yippee family.

89673:LOC114500945
gene id: 89673:LOC114500945
uniprot id: A0A6J2M5X4
uniprot id: A0A7E6E1Z5
uniprot id: A0A7E6E247
uniprot id: A0A7E6E2V9
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

89673:SPR
gene id: 89673:SPR
uniprot id: A0A6J2LV15
names: Similarity
messages: Belongs to the sepiapterin reductase family.

89673:SLC7A6
gene id: 89673:SLC7A6
uniprot id: A0A6J2KWV5
uniprot id: A0A7E6CLY8
uniprot id: A0A7E6CM19
names: Subcellular Location Annotation
messages: Membrane

89673:PAF1
gene id: 89673:PAF1
uniprot id: A0A6J2N5B3
uniprot id: A0A7E6CLC6
names: Similarity
messages: Belongs to the PAF1 family.

89673:VPS8
gene id: 89673:VPS8
uniprot id: A0A6J2KXI8
uniprot id: A0A6J2KZU4
names: Similarity
messages: Belongs to the VPS8 family.

89673:CMTR1
gene id: 89673:CMTR1
uniprot id: A0A6J2LG07
uniprot id: A0A7E6DLE6
uniprot id: A0A7E6DLS9
uniprot id: A0A7E6DLV7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with POLR2A (via C-terminus).
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

89673:BCHE
gene id: 89673:BCHE
uniprot id: A0A6J2L4G5
uniprot id: A0A7E6D5H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

89673:ATG2B
gene id: 89673:ATG2B
uniprot id: A0A6J2L5N8
uniprot id: A0A7E6CS12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

89673:EOMES
gene id: 89673:EOMES
uniprot id: A0A6J2M678
uniprot id: A0A6J2M978
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:PPRC1
gene id: 89673:PPRC1
uniprot id: A0A6J2LJ32
uniprot id: A0A6J2LME8
uniprot id: A0A7E6DVP9
uniprot id: A0A7E6DWH9
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114506811
gene id: 89673:LOC114506811
uniprot id: A0A6J2MM44
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

89673:TIMP2
gene id: 89673:TIMP2
uniprot id: A0A6J2M9A9
names: Similarity
names: Subunit
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Interacts (via the C-terminal) with MMP2 (via the C-terminal PEX domain); the interaction inhibits the MMP2 activity.

89673:PPOX
gene id: 89673:PPOX
uniprot id: A0A6J2KUU9
uniprot id: A0A6J2KVC3
uniprot id: A0A7E6CXB9
uniprot id: A0A7E6CZ56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

89673:KDM3B
gene id: 89673:KDM3B
uniprot id: A0A6J2N0U3
uniprot id: A0A7E6CSL4
uniprot id: A0A7E6CVC4
names: Subcellular Location Annotation
messages: Nucleus

89673:OTULIN
gene id: 89673:OTULIN
uniprot id: A0A6J2LR91
uniprot id: A0A7E6DA31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

89673:LOC118499667
gene id: 89673:LOC118499667
uniprot id: A0A7E6DEP1
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

89673:NUTM1
gene id: 89673:NUTM1
uniprot id: A0A7E6D1F3
names: Similarity
messages: Belongs to the NUT family.

89673:LOC114514088
gene id: 89673:LOC114514088
uniprot id: A0A6J2NB61
uniprot id: A0A7E6D842
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PARI family.
messages: Cytoplasm
messages: Nucleus

89673:LSR
gene id: 89673:LSR
uniprot id: A0A6J2MZA3
uniprot id: A0A6J2N5N2
uniprot id: A0A7E6CNJ1
uniprot id: A0A7E6CNN8
uniprot id: A0A7E6CNR1
uniprot id: A0A7E6CQX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

89673:MMD
gene id: 89673:MMD
uniprot id: A0A6J2MH19
uniprot id: A0A7E6EDZ5
uniprot id: A0A7E6EE48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

89673:IL15RA
gene id: 89673:IL15RA
uniprot id: A0A6J2L7C0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:DAXX
gene id: 89673:DAXX
uniprot id: A0A6J2LC76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAXX family.
messages: Cytoplasm
messages: PML body
messages: centromere
messages: nucleolus
messages: nucleoplasm

89673:LOC114500068
gene id: 89673:LOC114500068
uniprot id: A0A6J2LZL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DNAJC16
gene id: 89673:DNAJC16
uniprot id: A0A6J2LNW8
names: Subcellular Location Annotation
messages: Membrane

89673:HEXIM1
gene id: 89673:HEXIM1
uniprot id: A0A6J2MCT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

89673:SHROOM1
gene id: 89673:SHROOM1
uniprot id: A0A6J2MUG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

89673:LOC114508495
gene id: 89673:LOC114508495
uniprot id: A0A7E6D9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

89673:HCN1
gene id: 89673:HCN1
uniprot id: A0A6J2MH81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

89673:MDN1
gene id: 89673:MDN1
uniprot id: A0A7E6DMI7
uniprot id: A0A7E6DMI9
uniprot id: A0A7E6DN00
uniprot id: A0A7E6DN23
uniprot id: A0A7E6DN31
uniprot id: A0A7E6DNC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the midasin family.
messages: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.
messages: nucleolus
messages: nucleoplasm

89673:SH2B2
gene id: 89673:SH2B2
uniprot id: A0A6J2LYH8
uniprot id: A0A7E6DBC8
uniprot id: A0A7E6DBI9
names: Similarity
messages: Belongs to the SH2B adapter family.

89673:ARRDC4
gene id: 89673:ARRDC4
uniprot id: A0A6J2KSK4
names: Similarity
messages: Belongs to the arrestin family.

89673:DRD5
gene id: 89673:DRD5
uniprot id: A0A6J2LCG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:TNF
gene id: 89673:TNF
uniprot id: A0A6J2LJY4
uniprot id: A0A7E6DL56
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance (By similarity). Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6.
messages: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6.
messages: Homotrimer. Interacts with SPPL2B.
messages: Membrane
messages: O-glycosylated; glycans contain galactose, N-acetylgalactosamine and N-acetylneuraminic acid.
messages: Secreted
messages: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
messages: The membrane form, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the membrane form occurs by binding to soluble TNFRSF1A/TNFR1.
messages: The soluble form derives from the membrane form by proteolytic processing. The membrane-bound form is further proteolytically processed by SPPL2A or SPPL2B through regulated intramembrane proteolysis producing TNF intracellular domains (ICD1 and ICD2) released in the cytosol and TNF C-domain 1 and C-domain 2 secreted into the extracellular space.

89673:MED4
gene id: 89673:MED4
uniprot id: A0A6J2MQW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

89673:ASTE1
gene id: 89673:ASTE1
uniprot id: A0A6J2M490
names: Similarity
messages: Belongs to the asteroid family.

89673:LOC114496679
gene id: 89673:LOC114496679
uniprot id: A0A6J2LQM0
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:RPRM
gene id: 89673:RPRM
uniprot id: A0A6J2LCZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reprimo family.
messages: Cytoplasm
messages: Membrane

89673:USP7
gene id: 89673:USP7
uniprot id: A0A6J2L0D9
uniprot id: A0A7E6DCY2
names: Similarity
messages: Belongs to the peptidase C19 family.

89673:GUCY2C
gene id: 89673:GUCY2C
uniprot id: A0A6J2N8D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

89673:RPL24
gene id: 89673:RPL24
uniprot id: A0A6J2L3N8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

89673:DTNBP1
gene id: 89673:DTNBP1
uniprot id: A0A6J2LKI5
uniprot id: A0A7E6DT96
names: Similarity
messages: Belongs to the dysbindin family.

89673:CBS
gene id: 89673:CBS
uniprot id: A0A6J2KXZ4
uniprot id: A0A6J2KYJ1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

89673:ZSCAN2
gene id: 89673:ZSCAN2
uniprot id: A0A6J2KTY2
names: Subcellular Location Annotation
messages: Nucleus

89673:ABCG5
gene id: 89673:ABCG5
uniprot id: A0A6J2M0R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

89673:MYORG
gene id: 89673:MYORG
uniprot id: A0A7E6DFC5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

89673:LOC114506770
gene id: 89673:LOC114506770
uniprot id: A0A6J2MM02
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

89673:HYAL4
gene id: 89673:HYAL4
uniprot id: A0A6J2MN91
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

89673:LOC114511147
gene id: 89673:LOC114511147
uniprot id: A0A7E6CQA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:TMEM88
gene id: 89673:TMEM88
uniprot id: A0A6J2NEG5
uniprot id: A0A7E6ED33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

89673:THBD
gene id: 89673:THBD
uniprot id: A0A6J2MLG5
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with ITGAL, ITGAM and ITGB2.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

89673:PYCR2
gene id: 89673:PYCR2
uniprot id: A0A6J2N9P0
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

89673:LOC114490091
gene id: 89673:LOC114490091
uniprot id: A0A7E6DHE6
names: Subcellular Location Annotation
messages: Nucleus

89673:PABPC1
gene id: 89673:PABPC1
uniprot id: A0A6J2NIS2
uniprot id: A0A7E6E6J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

89673:ANKRD13A
gene id: 89673:ANKRD13A
uniprot id: A0A6J2MV60
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

89673:LOC114503540
gene id: 89673:LOC114503540
uniprot id: A0A6J2MAA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NLK
gene id: 89673:NLK
uniprot id: A0A6J2M5Z0
uniprot id: A0A6J2M9E6
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

89673:PSMA1
gene id: 89673:PSMA1
uniprot id: A0A6J2M2U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

89673:NAPB
gene id: 89673:NAPB
uniprot id: A0A6J2MHB4
uniprot id: A0A6J2MJ33
uniprot id: A0A6J2MJE9
uniprot id: A0A6J2MN73
uniprot id: A0A7E6CE97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

89673:STEAP4
gene id: 89673:STEAP4
uniprot id: A0A6J2MQ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

89673:MFSD11
gene id: 89673:MFSD11
uniprot id: A0A6J2M6U5
uniprot id: A0A7E6EFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

89673:ALX4
gene id: 89673:ALX4
uniprot id: A0A6J2LVU1
uniprot id: A0A7E6E1J1
names: Subcellular Location Annotation
messages: Nucleus

89673:MED12
gene id: 89673:MED12
uniprot id: A0A6J2MHS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

89673:LOC114510172
gene id: 89673:LOC114510172
uniprot id: A0A7E6CTX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

89673:TTC25
gene id: 89673:TTC25
uniprot id: A0A6J2MC66
uniprot id: A0A7E6EEP3
names: Subcellular Location Annotation
messages: cilium axoneme

89673:GALNT16
gene id: 89673:GALNT16
uniprot id: A0A6J2LDS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:CUL4A
gene id: 89673:CUL4A
uniprot id: A0A6J2MRL2
names: Similarity
messages: Belongs to the cullin family.

89673:GPR15
gene id: 89673:GPR15
uniprot id: A0A6J2L1H5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:IL36B
gene id: 89673:IL36B
uniprot id: A0A6J2LSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

89673:INTU
gene id: 89673:INTU
uniprot id: A0A6J2MAV1
uniprot id: A0A7E6E9R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inturned family.
messages: Cell surface
messages: cilium basal body

89673:LOC114489500
gene id: 89673:LOC114489500
uniprot id: A0A7E6CZJ1
names: Subcellular Location Annotation
messages: Nucleus

89673:MMP9
gene id: 89673:MMP9
uniprot id: A0A6J2MQZ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M10A family.
messages: Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with LCN2. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1.
messages: extracellular matrix

89673:LOC114505308
gene id: 89673:LOC114505308
uniprot id: A0A7E6D1D3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

89673:SV2A
gene id: 89673:SV2A
uniprot id: A0A6J2KUZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

89673:NEDD9
gene id: 89673:NEDD9
uniprot id: A0A6J2LH86
uniprot id: A0A7E6DU01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

89673:ROCK1
gene id: 89673:ROCK1
uniprot id: A0A6J2MQP7
uniprot id: A0A7E6CDQ2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.

89673:LOC114500555
gene id: 89673:LOC114500555
uniprot id: A0A6J2LZ92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:BARX2
gene id: 89673:BARX2
uniprot id: A0A6J2MYF6
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114500084
gene id: 89673:LOC114500084
uniprot id: A0A6J2M334
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOXL3
gene id: 89673:LOXL3
uniprot id: A0A6J2M5A6
uniprot id: A0A7E6DXY8
uniprot id: A0A7E6DY25
uniprot id: A0A7E6DY28
uniprot id: A0A7E6DZC0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

89673:GGCX
gene id: 89673:GGCX
uniprot id: A0A6J2LUE1
uniprot id: A0A7E6DY35
uniprot id: A0A7E6DZ24
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.
messages: Membrane

89673:STAC3
gene id: 89673:STAC3
uniprot id: A0A6J2N7J6
uniprot id: A0A7E6D5Z2
uniprot id: A0A7E6D8Q3
names: Subcellular Location Annotation
messages: sarcolemma

89673:SFXN4
gene id: 89673:SFXN4
uniprot id: A0A6J2LVI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

89673:FBXO46
gene id: 89673:FBXO46
uniprot id: A0A6J2N6F2
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

89673:TENT5D
gene id: 89673:TENT5D
uniprot id: A0A6J2MGC9
names: Similarity
messages: Belongs to the TENT family.

89673:SPON2
gene id: 89673:SPON2
uniprot id: A0A6J2KW44
names: Subcellular Location Annotation
messages: extracellular matrix

89673:TMEM192
gene id: 89673:TMEM192
uniprot id: A0A6J2M883
uniprot id: A0A7E6E8Z2
uniprot id: A0A7E6EA56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

89673:MARCKSL1
gene id: 89673:MARCKSL1
uniprot id: A0A6J2LM67
names: Similarity
messages: Belongs to the MARCKS family.

89673:SATB1
gene id: 89673:SATB1
uniprot id: A0A6J2M1E2
uniprot id: A0A6J2M2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

89673:LOC114513809
gene id: 89673:LOC114513809
uniprot id: A0A7E6D0A6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GRIN2B
gene id: 89673:GRIN2B
uniprot id: A0A6J2NHF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

89673:SLC10A6
gene id: 89673:SLC10A6
uniprot id: A0A6J2LAU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

89673:LOC114505553
gene id: 89673:LOC114505553
uniprot id: A0A7E6D1J5
names: Similarity
messages: Belongs to the pro/parathymosin family.

89673:LOC114494546
gene id: 89673:LOC114494546
uniprot id: A0A6J2LCN8
uniprot id: A0A6J2LDS4
uniprot id: A0A7E6DHU7
uniprot id: A0A7E6DHY7
uniprot id: A0A7E6DI08
uniprot id: A0A7E6DI33
uniprot id: A0A7E6DI57
names: Similarity
messages: Belongs to the AKAP110 family.

89673:LOC114512666
gene id: 89673:LOC114512666
uniprot id: A0A6J2NBT9
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114498054
gene id: 89673:LOC114498054
uniprot id: A0A6J2LVP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:BGN
gene id: 89673:BGN
uniprot id: A0A7E6CYS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Homodimer. Forms a ternary complex with MFAP2 and ELN.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

89673:FGD4
gene id: 89673:FGD4
uniprot id: A0A6J2N5G2
uniprot id: A0A6J2N7J9
names: Subcellular Location Annotation
messages: cytoskeleton

89673:GLDC
gene id: 89673:GLDC
uniprot id: A0A6J2N0C9
uniprot id: A0A7E6DET0
uniprot id: A0A7E6DEX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

89673:ATP5MC1
gene id: 89673:ATP5MC1
uniprot id: A0A6J2MHU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

89673:SNTB2
gene id: 89673:SNTB2
uniprot id: A0A6J2KR17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

89673:CDKAL1
gene id: 89673:CDKAL1
uniprot id: A0A6J2LMV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

89673:RPL7A
gene id: 89673:RPL7A
uniprot id: A0A6J2LXZ7
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

89673:LOC114500155
gene id: 89673:LOC114500155
uniprot id: A0A6J2M2X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:IL6R
gene id: 89673:IL6R
uniprot id: A0A6J2KUL2
uniprot id: A0A7E6CXJ4
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.

89673:GSK3B
gene id: 89673:GSK3B
uniprot id: A0A6J2L0L0
uniprot id: A0A6J2L2A3
uniprot id: A0A7E6D6V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Cytoplasm
messages: Nucleus

89673:SLC7A2
gene id: 89673:SLC7A2
uniprot id: A0A6J2MT85
uniprot id: A0A6J2MT96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

89673:SNAPIN
gene id: 89673:SNAPIN
uniprot id: A0A6J2KX42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAPIN family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling.
messages: synaptic vesicle membrane

89673:SLC9A3R2
gene id: 89673:SLC9A3R2
uniprot id: A0A6J2MJU4
uniprot id: A0A6J2MJV9
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

89673:AGTR2
gene id: 89673:AGTR2
uniprot id: A0A6J2MLH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MTUS1.
messages: Membrane

89673:LOC114494392
gene id: 89673:LOC114494392
uniprot id: A0A6J2LE61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

89673:PIGU
gene id: 89673:PIGU
uniprot id: A0A6J2MLX8
uniprot id: A0A7E6CFC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:SLC13A4
gene id: 89673:SLC13A4
uniprot id: A0A6J2MUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

89673:GSTM4
gene id: 89673:GSTM4
uniprot id: A0A7E6CXT5
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

89673:NDUFA6
gene id: 89673:NDUFA6
uniprot id: A0A6J2NFB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:TMEM63A
gene id: 89673:TMEM63A
uniprot id: A0A6J2N5B5
uniprot id: A0A7E6D0R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

89673:MRPL20
gene id: 89673:MRPL20
uniprot id: A0A6J2LM51
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

89673:VPS35L
gene id: 89673:VPS35L
uniprot id: A0A6J2LHF9
uniprot id: A0A7E6DE53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS35L family.
messages: Endosome

89673:LOC114491737
gene id: 89673:LOC114491737
uniprot id: A0A6J2L7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:KCNE5
gene id: 89673:KCNE5
uniprot id: A0A6J2MGK1
names: Similarity
messages: Belongs to the potassium channel KCNE family.

89673:LOC114500117
gene id: 89673:LOC114500117
uniprot id: A0A6J2M378
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114498872
gene id: 89673:LOC114498872
uniprot id: A0A6J2LUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SHANK3
gene id: 89673:SHANK3
uniprot id: A0A6J2N9Q2
uniprot id: A0A7E6D8X1
uniprot id: A0A7E6D902
uniprot id: A0A7E6D9Q2
uniprot id: A0A7E6DBS1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.
messages: Postsynaptic density

89673:CCR7
gene id: 89673:CCR7
uniprot id: A0A6J2MCY1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:GALNT10
gene id: 89673:GALNT10
uniprot id: A0A6J2N2U5
uniprot id: A0A7E6CT01
uniprot id: A0A7E6CT89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC114499141
gene id: 89673:LOC114499141
uniprot id: A0A6J2LV29
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

89673:LOC118502221
gene id: 89673:LOC118502221
uniprot id: A0A7E6EE16
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

89673:WDR48
gene id: 89673:WDR48
uniprot id: A0A6J2M8D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Endosome
messages: Late endosome

89673:PSMB1
gene id: 89673:PSMB1
uniprot id: A0A6J2KWN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

89673:TLR9
gene id: 89673:TLR9
uniprot id: A0A7E6E481
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Endosome
messages: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production.
messages: Lysosome
messages: Membrane
messages: phagosome

89673:ME1
gene id: 89673:ME1
uniprot id: A0A6J2LH36
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

89673:SELENOI
gene id: 89673:SELENOI
uniprot id: A0A6J2M419
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

89673:MLH1
gene id: 89673:MLH1
uniprot id: A0A6J2M455
uniprot id: A0A7E6E4X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

89673:LOC118499944
gene id: 89673:LOC118499944
uniprot id: A0A7E6DHK0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

89673:CDK5R1
gene id: 89673:CDK5R1
uniprot id: A0A6J2MBW4
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

89673:ANAPC5
gene id: 89673:ANAPC5
uniprot id: A0A6J2MUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

89673:RDX
gene id: 89673:RDX
uniprot id: A0A7E6E0E5
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

89673:C14H1orf43
gene id: 89673:C14H1orf43
uniprot id: A0A6J2KSG6
uniprot id: A0A6J2KT17
uniprot id: A0A6J2KUL8
uniprot id: A0A6J2KWB9
uniprot id: A0A6J2KYF7
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

89673:SEMA4F
gene id: 89673:SEMA4F
uniprot id: A0A6J2M1E6
uniprot id: A0A6J2M5M8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114505158
gene id: 89673:LOC114505158
uniprot id: A0A6J2ML23
uniprot id: A0A7E6D0U9
uniprot id: A0A7E6D1S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the V0 complex of the vacuolar ATPase (V-ATPase).
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

89673:DDX52
gene id: 89673:DDX52
uniprot id: A0A6J2MAV6
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.

89673:GLYAT
gene id: 89673:GLYAT
uniprot id: A0A6J2M0E8
uniprot id: A0A7E6E211
uniprot id: A0A7E6E257
uniprot id: A0A7E6E2V4
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

89673:APOBEC1
gene id: 89673:APOBEC1
uniprot id: A0A6J2NGP7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

89673:CLSTN3
gene id: 89673:CLSTN3
uniprot id: A0A6J2N7G8
uniprot id: A0A7E6D7W9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

89673:PCK2
gene id: 89673:PCK2
uniprot id: A0A6J2L3W7
uniprot id: A0A6J2L8H3
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

89673:LOC114497962
gene id: 89673:LOC114497962
uniprot id: A0A6J2LPT7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TNKS
gene id: 89673:TNKS
uniprot id: A0A6J2MRS4
names: Function
names: Similarity
messages: Belongs to the ARTD/PARP family.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

89673:SPRTN
gene id: 89673:SPRTN
uniprot id: A0A6J2N594
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spartan family.
messages: Chromosome
messages: Nucleus

89673:LOC114500508
gene id: 89673:LOC114500508
uniprot id: A0A6J2M176
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TSPO
gene id: 89673:TSPO
uniprot id: A0A6J2NA12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane
messages: Mitochondrion membrane

89673:KIF14
gene id: 89673:KIF14
uniprot id: A0A6J2N382
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:ALDH8A1
gene id: 89673:ALDH8A1
uniprot id: A0A6J2LHW8
uniprot id: A0A7E6DNS4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

89673:P2RY8
gene id: 89673:P2RY8
uniprot id: A0A6J2KZR2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:AJAP1
gene id: 89673:AJAP1
uniprot id: A0A7E6DQP1
names: Subcellular Location Annotation
messages: Membrane

89673:RIC8B
gene id: 89673:RIC8B
uniprot id: A0A6J2N4Y7
uniprot id: A0A6J2N6R2
uniprot id: A0A6J2N6X7
uniprot id: A0A6J2NC77
uniprot id: A0A7E6D8S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

89673:SOX3
gene id: 89673:SOX3
uniprot id: A0A6J2MMC9
names: Subcellular Location Annotation
messages: Nucleus

89673:DOLPP1
gene id: 89673:DOLPP1
uniprot id: A0A6J2LVN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

89673:LOC114494261
gene id: 89673:LOC114494261
uniprot id: A0A6J2LBC4
names: Similarity
messages: Belongs to the histone H2B family.

89673:CAP1
gene id: 89673:CAP1
uniprot id: A0A6J2LQM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.
messages: Homodimer. Binds actin monomers.
messages: Membrane

89673:MICOS13
gene id: 89673:MICOS13
uniprot id: A0A6J2MDE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

89673:PAPPA
gene id: 89673:PAPPA
uniprot id: A0A6J2N597
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114512767
gene id: 89673:LOC114512767
uniprot id: A0A6J2N742
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:PTPN2
gene id: 89673:PTPN2
uniprot id: A0A6J2MP71
uniprot id: A0A7E6CE77
uniprot id: A0A7E6CES1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

89673:CIAO2A
gene id: 89673:CIAO2A
uniprot id: A0A6J2L7R4
uniprot id: A0A6J2L898
uniprot id: A0A7E6CD86
names: Similarity
messages: Belongs to the MIP18 family.

89673:PPP2R2A
gene id: 89673:PPP2R2A
uniprot id: A0A6J2M994
uniprot id: A0A7E6ECD1
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

89673:TMPRSS11A
gene id: 89673:TMPRSS11A
uniprot id: A0A7E6DDV5
uniprot id: A0A7E6DDW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

89673:LOC114490448
gene id: 89673:LOC114490448
uniprot id: A0A6J2L033
names: Similarity
messages: Belongs to the ARTD/PARP family.

89673:PHKG1
gene id: 89673:PHKG1
uniprot id: A0A7E6DBR6
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

89673:ALDOA
gene id: 89673:ALDOA
uniprot id: A0A6J2LDA1
uniprot id: A0A6J2LI20
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

89673:LOC114502887
gene id: 89673:LOC114502887
uniprot id: A0A6J2MCT6
names: Similarity
messages: Belongs to the intermediate filament family.

89673:SLC28A3
gene id: 89673:SLC28A3
uniprot id: A0A6J2L093
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

89673:XKRX
gene id: 89673:XKRX
uniprot id: A0A6J2MH11
uniprot id: A0A7E6CZH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

89673:TRMT1L
gene id: 89673:TRMT1L
uniprot id: A0A6J2N1W0
uniprot id: A0A7E6CVS6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

89673:TCP1
gene id: 89673:TCP1
uniprot id: A0A6J2LFR7
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

89673:ATP2A2
gene id: 89673:ATP2A2
uniprot id: A0A6J2MW64
uniprot id: A0A6J2N2D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

89673:BRINP3
gene id: 89673:BRINP3
uniprot id: A0A6J2N3N7
names: Similarity
messages: Belongs to the BRINP family.

89673:LOC114513054
gene id: 89673:LOC114513054
uniprot id: A0A7E6D6V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CNN2
gene id: 89673:CNN2
uniprot id: A0A6J2ME07
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

89673:HARBI1
gene id: 89673:HARBI1
uniprot id: A0A7E6E106
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

89673:C9H18orf32
gene id: 89673:C9H18orf32
uniprot id: A0A6J2MKM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPF0729 family.
messages: Interacts with DERL1 and AMFR.
messages: May activate the NF-kappa-B signaling pathway.

89673:KCNC3
gene id: 89673:KCNC3
uniprot id: A0A6J2N377
uniprot id: A0A7E6CNM5
uniprot id: A0A7E6CNP6
uniprot id: A0A7E6CQV6
names: Subcellular Location Annotation
messages: Membrane

89673:RPS21
gene id: 89673:RPS21
uniprot id: A0A6J2MQR0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

89673:ZNF274
gene id: 89673:ZNF274
uniprot id: A0A6J2N8I7
uniprot id: A0A7E6CQP6
uniprot id: A0A7E6CR08
names: Subcellular Location Annotation
messages: Nucleus

89673:OLA1
gene id: 89673:OLA1
uniprot id: A0A6J2LFZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.
messages: Nucleus
messages: nucleolus

89673:ELK3
gene id: 89673:ELK3
uniprot id: A0A6J2N6A2
uniprot id: A0A7E6DAP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:BUD13
gene id: 89673:BUD13
uniprot id: A0A7E6DYX5
uniprot id: A0A7E6DZE6
names: Similarity
messages: Belongs to the CWC26 family.

89673:PGAM2
gene id: 89673:PGAM2
uniprot id: A0A6J2L2Y3
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

89673:PKD2L2
gene id: 89673:PKD2L2
uniprot id: A0A7E6CUK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane

89673:LOC114507542
gene id: 89673:LOC114507542
uniprot id: A0A7E6CI67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

89673:NPPA
gene id: 89673:NPPA
uniprot id: A0A6J2LVT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the natriuretic peptide family.
messages: Cell projection
messages: Homodimer; disulfide-linked antiparallel dimer.
messages: Hormone produced in the kidneys that appears to be important for maintaining cardio-renal homeostasis. Mediates vasodilation, natriuresis and diuresis primarily in the renal system, in order to maintain the extracellular fluid volume and control the fluid-electrolyte balance. Specifically binds and stimulates cGMP production by renal transmembrane receptors, likely NPR1. Urodilatin not ANP, may be the natriuretic peptide responsible for the regulation of sodium and water homeostasis in the kidney.
messages: May have a role in cardio-renal homeostasis through regulation of diuresis and inhibiting aldosterone synthesis. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase. May have a role in potassium excretion but not sodium excretion (natriuresis). Possibly enhances protein excretion in urine by decreasing proximal tubular protein reabsorption.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis and in vitro, vasodilates renal artery strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, selectively vasodilates intestinal and vascular smooth muscle strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, selectively vasodilates intestinal smooth muscle but not vascular smooth muscle strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis, diuresis, and vasodilation. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase. However reports on the involvement of this peptide in mammal blood volume and blood pressure homeostasis are conflicting; according to a report it is not sufficient to activate cGMP and does not inhibit collecting duct transport nor effect diuresis and natriuresis. Appears to bind to specific receptors that are distinct from the receptors bound by the atrial natriuretic and long-acting natriuretic peptides. Possibly functions in protein excretion in urine by maintaining the integrity of the proximal tubules and enhancing protein excretion by decreasing proximal tubular protein reabsorption.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis, diuresis, vasodilation, and inhibiting aldosterone synthesis. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase (By similarity). However reports on the involvement of this peptide in mammal blood volume and blood pressure homeostasis are conflicting; according to a report, in vivo it is not sufficient to activate cGMP and does not inhibit collecting duct transport nor effect diuresis and natriuresis (By similarity). Appears to bind to specific receptors that are distinct from the receptors bound by atrial natriuretic peptide and vessel dilator. Possibly enhances protein excretion in urine by decreasing proximal tubular protein reabsorption.
messages: May have a role in cardio-renal homeostasis through regulation of regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, vasodilates intestinal smooth muscle but not smooth muscle strips.
messages: Secreted

89673:C8A
gene id: 89673:C8A
uniprot id: A0A6J2LTA4
uniprot id: A0A7E6DS63
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

89673:TMPRSS9
gene id: 89673:TMPRSS9
uniprot id: A0A7E6E9V0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:THEMIS
gene id: 89673:THEMIS
uniprot id: A0A7E6DN38
uniprot id: A0A7E6DNS0
names: Similarity
messages: Belongs to the themis family.

89673:UBE2G2
gene id: 89673:UBE2G2
uniprot id: A0A6J2KYX5
uniprot id: A0A7E6D2E0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:PPP2R5D
gene id: 89673:PPP2R5D
uniprot id: A0A6J2LGI1
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

89673:CTDP1
gene id: 89673:CTDP1
uniprot id: A0A6J2MIJ1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

89673:LOC114500237
gene id: 89673:LOC114500237
uniprot id: A0A6J2LZA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CLRN3
gene id: 89673:CLRN3
uniprot id: A0A6J2LJ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

89673:TXLNB
gene id: 89673:TXLNB
uniprot id: A0A6J2LHH5
names: Similarity
messages: Belongs to the taxilin family.

89673:UHRF1
gene id: 89673:UHRF1
uniprot id: A0A6J2MCH2
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114489529
gene id: 89673:LOC114489529
uniprot id: A0A6J2KWT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:LOC114510937
gene id: 89673:LOC114510937
uniprot id: A0A7E6CQX8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

89673:LXN
gene id: 89673:LXN
uniprot id: A0A6J2L1Y3
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

89673:KRI1
gene id: 89673:KRI1
uniprot id: A0A6J2M745
names: Similarity
messages: Belongs to the KRI1 family.

89673:CSGALNACT2
gene id: 89673:CSGALNACT2
uniprot id: A0A6J2LRM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

89673:SLC26A8
gene id: 89673:SLC26A8
uniprot id: A0A6J2LFF7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:DMRT1
gene id: 89673:DMRT1
uniprot id: A0A6J2MSI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

89673:LOC114490131
gene id: 89673:LOC114490131
uniprot id: A0A6J2L2L6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

89673:RAB27A
gene id: 89673:RAB27A
uniprot id: A0A6J2LE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

89673:UBLCP1
gene id: 89673:UBLCP1
uniprot id: A0A6J2MVC3
uniprot id: A0A7E6CSS1
names: Function
names: Subcellular Location Annotation
messages: Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.
messages: Nucleus

89673:MTCH2
gene id: 89673:MTCH2
uniprot id: A0A6J2M288
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:PPP1R2C
gene id: 89673:PPP1R2C
uniprot id: A0A6J2MGP1
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

89673:MYBBP1A
gene id: 89673:MYBBP1A
uniprot id: A0A6J2NDM6
uniprot id: A0A7E6ECL9
uniprot id: A0A7E6EDT1
names: Similarity
messages: Belongs to the MYBBP1A family.

89673:KRT79
gene id: 89673:KRT79
uniprot id: A0A6J2NCP2
names: Similarity
messages: Belongs to the intermediate filament family.

89673:CNDP2
gene id: 89673:CNDP2
uniprot id: A0A6J2MQC7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

89673:LOC114492756
gene id: 89673:LOC114492756
uniprot id: A0A7E6E284
names: Similarity
messages: Belongs to the NipSnap family.

89673:ATP6V0D1
gene id: 89673:ATP6V0D1
uniprot id: A0A6J2KWD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

89673:ANKRD13B
gene id: 89673:ANKRD13B
uniprot id: A0A6J2MFS4
uniprot id: A0A7E6EDS8
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

89673:TNK1
gene id: 89673:TNK1
uniprot id: A0A6J2NE04
names: Subcellular Location Annotation
messages: Cell membrane

89673:LOC114496360
gene id: 89673:LOC114496360
uniprot id: A0A6J2LN54
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:ZHX1
gene id: 89673:ZHX1
uniprot id: A0A7E6E6S1
uniprot id: A0A7E6E8K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

89673:EIF2AK3
gene id: 89673:EIF2AK3
uniprot id: A0A6J2LHB5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

89673:PLCB2
gene id: 89673:PLCB2
uniprot id: A0A6J2L3S0
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

89673:LOC114492511
gene id: 89673:LOC114492511
uniprot id: A0A7E6CQJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus

89673:APOA5
gene id: 89673:APOA5
uniprot id: A0A6J2M2Q9
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

89673:FABP1
gene id: 89673:FABP1
uniprot id: A0A6J2M500
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

89673:STX6
gene id: 89673:STX6
uniprot id: A0A6J2N9W2
names: Similarity
messages: Belongs to the syntaxin family.

89673:SYPL2
gene id: 89673:SYPL2
uniprot id: A0A6J2KUJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

89673:GRHL2
gene id: 89673:GRHL2
uniprot id: A0A6J2NB45
uniprot id: A0A7E6E6K3
uniprot id: A0A7E6E7E9
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114514597
gene id: 89673:LOC114514597
uniprot id: A0A6J2NAT8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:LOC114513638
gene id: 89673:LOC114513638
uniprot id: A0A7E6D8G3
names: Similarity
messages: Belongs to the cullin family.

89673:P2RX1
gene id: 89673:P2RX1
uniprot id: A0A6J2NEC2
uniprot id: A0A7E6ECN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

89673:LOC114490346
gene id: 89673:LOC114490346
uniprot id: A0A6J2L1F8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MYOG
gene id: 89673:MYOG
uniprot id: A0A6J2NAG3
uniprot id: A0A7E6D0S4
names: Subcellular Location Annotation
messages: Nucleus

89673:MMP24
gene id: 89673:MMP24
uniprot id: A0A6J2ML45
names: Similarity
messages: Belongs to the peptidase M10A family.

89673:SLAIN2
gene id: 89673:SLAIN2
uniprot id: A0A6J2L291
uniprot id: A0A6J2L759
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

89673:UBN2
gene id: 89673:UBN2
uniprot id: A0A7E6CIR9
uniprot id: A0A7E6CJ23
uniprot id: A0A7E6CKX1
names: Similarity
messages: Belongs to the ubinuclein family.

89673:LOC114499098
gene id: 89673:LOC114499098
uniprot id: A0A6J2LU35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ALAS2
gene id: 89673:ALAS2
uniprot id: A0A6J2MGH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

89673:IRAK4
gene id: 89673:IRAK4
uniprot id: A0A6J2NH27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

89673:DCBLD2
gene id: 89673:DCBLD2
uniprot id: A0A6J2KZK5
uniprot id: A0A7E6D3U7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC118499353
gene id: 89673:LOC118499353
uniprot id: A0A7E6D9Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:LOC114490323
gene id: 89673:LOC114490323
uniprot id: A0A6J2L376
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PPP2CB
gene id: 89673:PPP2CB
uniprot id: A0A6J2MT60
names: Similarity
messages: Belongs to the PPP phosphatase family.

89673:DDIT4L
gene id: 89673:DDIT4L
uniprot id: A0A6J2L8I8
names: Similarity
messages: Belongs to the DDIT4 family.

89673:C13H12orf43
gene id: 89673:C13H12orf43
uniprot id: A0A6J2MVN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

89673:LOC114500254
gene id: 89673:LOC114500254
uniprot id: A0A6J2M3A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LARS1
gene id: 89673:LARS1
uniprot id: A0A6J2MSP1
uniprot id: A0A7E6CU17
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

89673:DCST2
gene id: 89673:DCST2
uniprot id: A0A6J2KW96
names: Subcellular Location Annotation
messages: Membrane

89673:FAM83B
gene id: 89673:FAM83B
uniprot id: A0A6J2LIA0
names: Similarity
messages: Belongs to the FAM83 family.

89673:LOC114508007
gene id: 89673:LOC114508007
uniprot id: A0A7E6CHD5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

89673:MAT2B
gene id: 89673:MAT2B
uniprot id: A0A6J2MY46
uniprot id: A0A6J2N3G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

89673:ELOVL6
gene id: 89673:ELOVL6
uniprot id: A0A6J2L6U6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

89673:ACHE
gene id: 89673:ACHE
uniprot id: A0A6J2M5S5
uniprot id: A0A6J2M684
uniprot id: A0A6J2M690
uniprot id: A0A7E6DBH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

89673:PSME2
gene id: 89673:PSME2
uniprot id: A0A6J2L8H1
uniprot id: A0A6J2LCN1
uniprot id: A0A6J2LDP5
names: Similarity
messages: Belongs to the PA28 family.

89673:MYO1E
gene id: 89673:MYO1E
uniprot id: A0A6J2L472
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:SNCA
gene id: 89673:SNCA
uniprot id: A0A6J2L5S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse
messages: axon

89673:LETM1
gene id: 89673:LETM1
uniprot id: A0A6J2L024
uniprot id: A0A7E6D3V2
uniprot id: A0A7E6D3W6
uniprot id: A0A7E6D4E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LETM1 family.
messages: Membrane
messages: Mitochondrion inner membrane

89673:DERL3
gene id: 89673:DERL3
uniprot id: A0A6J2MVV6
uniprot id: A0A6J2N0F7
uniprot id: A0A6J2N114
uniprot id: A0A7E6CT67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114489568
gene id: 89673:LOC114489568
uniprot id: A0A6J2KXD7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

89673:LOC114497143
gene id: 89673:LOC114497143
uniprot id: A0A6J2LRK1
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

89673:ARPC1B
gene id: 89673:ARPC1B
uniprot id: A0A6J2MCY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

89673:NOTCH4
gene id: 89673:NOTCH4
uniprot id: A0A7E6DLC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

89673:MTUS1
gene id: 89673:MTUS1
uniprot id: A0A6J2MQL1
uniprot id: A0A6J2MQL6
uniprot id: A0A6J2MX95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTUS1 family.
messages: Nucleus

89673:SLC24A4
gene id: 89673:SLC24A4
uniprot id: A0A6J2L845
uniprot id: A0A6J2LC36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

89673:PLOD2
gene id: 89673:PLOD2
uniprot id: A0A6J2KXU5
uniprot id: A0A6J2L1S2
uniprot id: A0A7E6D3B0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

89673:LOC114489781
gene id: 89673:LOC114489781
uniprot id: A0A6J2KVL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NUF2
gene id: 89673:NUF2
uniprot id: A0A6J2N4B7
names: Similarity
messages: Belongs to the NUF2 family.

89673:SNX21
gene id: 89673:SNX21
uniprot id: A0A6J2MPV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

89673:PHLDA1
gene id: 89673:PHLDA1
uniprot id: A0A6J2L1L4
uniprot id: A0A7E6D5L0
names: Subcellular Location Annotation
messages: Cytoplasm

89673:RIOK3
gene id: 89673:RIOK3
uniprot id: A0A6J2MNV0
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
messages: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.

89673:ARL2
gene id: 89673:ARL2
uniprot id: A0A6J2LUS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

89673:LOC114492418
gene id: 89673:LOC114492418
uniprot id: A0A6J2L2A5
uniprot id: A0A6J2L2Y0
uniprot id: A0A6J2L471
uniprot id: A0A6J2L577
uniprot id: A0A6J2L987
uniprot id: A0A7E6DP47
uniprot id: A0A7E6DP48
uniprot id: A0A7E6DP52
uniprot id: A0A7E6DPN8
uniprot id: A0A7E6DPU2
uniprot id: A0A7E6DPU7
uniprot id: A0A7E6DPV2
uniprot id: A0A7E6DQ76
uniprot id: A0A7E6DQ81
names: Similarity
messages: Belongs to the aldo/keto reductase family.

89673:SDR42E2
gene id: 89673:SDR42E2
uniprot id: A0A7E6DE54
names: Similarity
messages: Belongs to the 3-beta-HSD family.

89673:CD164
gene id: 89673:CD164
uniprot id: A0A6J2LCC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

89673:CASP9
gene id: 89673:CASP9
uniprot id: A0A6J2LQ56
names: Similarity
messages: Belongs to the peptidase C14A family.

89673:LOC114500690
gene id: 89673:LOC114500690
uniprot id: A0A6J2M114
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SULT2A1
gene id: 89673:SULT2A1
uniprot id: A0A6J2N7Q4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:GRAMD1A
gene id: 89673:GRAMD1A
uniprot id: A0A6J2MYJ7
uniprot id: A0A6J2N070
uniprot id: A0A6J2N4V7
uniprot id: A0A7E6CMU9
uniprot id: A0A7E6CMV4
uniprot id: A0A7E6CMV9
uniprot id: A0A7E6CMW3
uniprot id: A0A7E6CN04
uniprot id: A0A7E6CN07
uniprot id: A0A7E6CQ96
uniprot id: A0A7E6CQA1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:HYAL2
gene id: 89673:HYAL2
uniprot id: A0A7E6E3Q4
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

89673:LOC114499877
gene id: 89673:LOC114499877
uniprot id: A0A6J2M1U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:EXOC3L4
gene id: 89673:EXOC3L4
uniprot id: A0A7E6CTC1
names: Similarity
messages: Belongs to the SEC6 family.

89673:SKA2
gene id: 89673:SKA2
uniprot id: A0A7E6EDY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA2 family.
messages: spindle

89673:NTF3
gene id: 89673:NTF3
uniprot id: A0A6J2NDV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

89673:TMTC3
gene id: 89673:TMTC3
uniprot id: A0A6J2ND45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

89673:LOC114506544
gene id: 89673:LOC114506544
uniprot id: A0A6J2ML44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

89673:BCAN
gene id: 89673:BCAN
uniprot id: A0A7E6CWJ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:ATP10A
gene id: 89673:ATP10A
uniprot id: A0A6J2KZH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

89673:LOC114515481
gene id: 89673:LOC114515481
uniprot id: A0A7E6D046
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

89673:STT3A
gene id: 89673:STT3A
uniprot id: A0A6J2MUQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

89673:TGFBR2
gene id: 89673:TGFBR2
uniprot id: A0A6J2M7G4
uniprot id: A0A7E6E639
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

89673:TAGLN3
gene id: 89673:TAGLN3
uniprot id: A0A6J2KY00
names: Similarity
messages: Belongs to the calponin family.

89673:SFPQ
gene id: 89673:SFPQ
uniprot id: A0A6J2LHB0
uniprot id: A0A7E6DRR7
names: Subcellular Location Annotation
messages: Nucleus speckle

89673:FZD3
gene id: 89673:FZD3
uniprot id: A0A6J2MA21
uniprot id: A0A7E6E8F9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:GTF2E2
gene id: 89673:GTF2E2
uniprot id: A0A6J2MY50
uniprot id: A0A7E6CKY3
uniprot id: A0A7E6CN00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

89673:ATP1B1
gene id: 89673:ATP1B1
uniprot id: A0A6J2N2E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Cell membrane
messages: Involved in cell adhesion and establishing epithelial cell polarity.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.
messages: sarcolemma

89673:TSHZ2
gene id: 89673:TSHZ2
uniprot id: A0A6J2ML59
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

89673:LOC114512833
gene id: 89673:LOC114512833
uniprot id: A0A6J2NC15
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

89673:LOC114510241
gene id: 89673:LOC114510241
uniprot id: A0A6J2MX10
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114511145
gene id: 89673:LOC114511145
uniprot id: A0A6J2N182
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:LOC114501300
gene id: 89673:LOC114501300
uniprot id: A0A7E6E8Z0
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

89673:SKAP2
gene id: 89673:SKAP2
uniprot id: A0A6J2MU53
names: Similarity
messages: Belongs to the SKAP family.

89673:C9H20orf27
gene id: 89673:C9H20orf27
uniprot id: A0A6J2MMN8
names: Similarity
messages: Belongs to the UPF0687 family.

89673:PRKAB2
gene id: 89673:PRKAB2
uniprot id: A0A6J2KT64
uniprot id: A0A6J2KUR2
uniprot id: A0A6J2KWG4
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

89673:RPL22
gene id: 89673:RPL22
uniprot id: A0A6J2LNJ5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

89673:IPO7
gene id: 89673:IPO7
uniprot id: A0A6J2M0R3
names: Subcellular Location Annotation
messages: Cytoplasm

89673:UROD
gene id: 89673:UROD
uniprot id: A0A6J2LR69
uniprot id: A0A7E6DRL9
uniprot id: A0A7E6DSA6
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

89673:LOC114512854
gene id: 89673:LOC114512854
uniprot id: A0A6J2N7D2
names: Similarity
messages: Belongs to the intermediate filament family.

89673:ATP5F1D
gene id: 89673:ATP5F1D
uniprot id: A0A6J2MEE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase epsilon chain family.
messages: Mitochondrion inner membrane

89673:LOC114513375
gene id: 89673:LOC114513375
uniprot id: A0A6J2NE73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CHRNA3
gene id: 89673:CHRNA3
uniprot id: A0A6J2KV78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:RPL5
gene id: 89673:RPL5
uniprot id: A0A6J2LN50
uniprot id: A0A7E6DSZ2
uniprot id: A0A7E6DTK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

89673:RPL38
gene id: 89673:RPL38
uniprot id: A0A6J2MDX2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

89673:LOC114513221
gene id: 89673:LOC114513221
uniprot id: A0A6J2NE41
names: Similarity
messages: Belongs to the intermediate filament family.

89673:NOTCH3
gene id: 89673:NOTCH3
uniprot id: A0A6J2M716
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

89673:TLCD1
gene id: 89673:TLCD1
uniprot id: A0A6J2M928
names: Subcellular Location Annotation
messages: Membrane

89673:FGB
gene id: 89673:FGB
uniprot id: A0A7E6EA46
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

89673:MYO1H
gene id: 89673:MYO1H
uniprot id: A0A7E6CV49
uniprot id: A0A7E6CVE8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:B4GALNT1
gene id: 89673:B4GALNT1
uniprot id: A0A6J2NAM5
uniprot id: A0A6J2NFP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC114505295
gene id: 89673:LOC114505295
uniprot id: A0A6J2MLD8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:DLST
gene id: 89673:DLST
uniprot id: A0A6J2L746
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

89673:COQ6
gene id: 89673:COQ6
uniprot id: A0A6J2L3D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

89673:NME9
gene id: 89673:NME9
uniprot id: A0A6J2M7M6
uniprot id: A0A6J2M882
uniprot id: A0A7E6E5I9
uniprot id: A0A7E6E6H1
names: Similarity
messages: Belongs to the NDK family.

89673:EMC1
gene id: 89673:EMC1
uniprot id: A0A6J2LME0
uniprot id: A0A6J2LNQ6
uniprot id: A0A7E6DQ30
uniprot id: A0A7E6DQ48
uniprot id: A0A7E6DQR2
uniprot id: A0A7E6DQR7
uniprot id: A0A7E6DR93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114510724
gene id: 89673:LOC114510724
uniprot id: A0A6J2N503
names: Similarity
messages: Belongs to the MHC class I family.

89673:DOC2A
gene id: 89673:DOC2A
uniprot id: A0A6J2MQ97
uniprot id: A0A7E6DCN3
names: Subcellular Location Annotation
messages: Membrane

89673:CHI3L1
gene id: 89673:CHI3L1
uniprot id: A0A6J2NAY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Endoplasmic reticulum
messages: Monomer.
messages: extracellular space
messages: perinuclear region

89673:ATP5MG
gene id: 89673:ATP5MG
uniprot id: A0A6J2M1H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

89673:UTP15
gene id: 89673:UTP15
uniprot id: A0A6J2MUA5
names: Subcellular Location Annotation
messages: nucleolus

89673:ELOVL4
gene id: 89673:ELOVL4
uniprot id: A0A6J2LKN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May play a critical role in early brain and skin development.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Oligomer.
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

89673:TLR10
gene id: 89673:TLR10
uniprot id: A0A6J2L7Y1
uniprot id: A0A7E6D8R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

89673:LOC114499015
gene id: 89673:LOC114499015
uniprot id: A0A6J2LUS2
uniprot id: A0A7E6E1T5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:UBL3
gene id: 89673:UBL3
uniprot id: A0A6J2L058
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:HAO2
gene id: 89673:HAO2
uniprot id: A0A6J2KTX3
uniprot id: A0A7E6CW87
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

89673:PRKX
gene id: 89673:PRKX
uniprot id: A0A6J2KVW0
uniprot id: A0A7E6D1I0
uniprot id: A0A7E6D486
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:FAN1
gene id: 89673:FAN1
uniprot id: A0A6J2KSC9
uniprot id: A0A7E6CPP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

89673:RBKS
gene id: 89673:RBKS
uniprot id: A0A6J2LXF3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

89673:LOC114503643
gene id: 89673:LOC114503643
uniprot id: A0A6J2MCQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ARHGEF2
gene id: 89673:ARHGEF2
uniprot id: A0A6J2KSJ1
uniprot id: A0A6J2KT42
uniprot id: A0A7E6CWR7
uniprot id: A0A7E6CX95
uniprot id: A0A7E6CXL6
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: Vesicle
messages: spindle
messages: tight junction

89673:LOC114499470
gene id: 89673:LOC114499470
uniprot id: A0A7E6DY94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

89673:MBOAT7
gene id: 89673:MBOAT7
uniprot id: A0A6J2N7V9
uniprot id: A0A7E6CNL7
uniprot id: A0A7E6CR10
names: Subcellular Location Annotation
messages: Membrane

89673:DHRS7C
gene id: 89673:DHRS7C
uniprot id: A0A6J2ND34
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:SLX1A
gene id: 89673:SLX1A
uniprot id: A0A6J2M0Q9
uniprot id: A0A6J2M219
uniprot id: A0A7E6DDQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:TSC22D2
gene id: 89673:TSC22D2
uniprot id: A0A6J2NE84
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

89673:SMARCA2
gene id: 89673:SMARCA2
uniprot id: A0A6J2LTI7
uniprot id: A0A6J2LXS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

89673:RRP12
gene id: 89673:RRP12
uniprot id: A0A6J2LPW9
names: Similarity
messages: Belongs to the RRP12 family.

89673:FOXI1
gene id: 89673:FOXI1
uniprot id: A0A6J2N3K5
names: Subcellular Location Annotation
messages: Nucleus

89673:FBXL5
gene id: 89673:FBXL5
uniprot id: A0A6J2L241
uniprot id: A0A7E6D6A4
names: Subcellular Location Annotation
messages: perinuclear region

89673:ATP6V1C1
gene id: 89673:ATP6V1C1
uniprot id: A0A6J2NB02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

89673:RND3
gene id: 89673:RND3
uniprot id: A0A6J2LAV6
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

89673:NGLY1
gene id: 89673:NGLY1
uniprot id: A0A6J2M1K2
uniprot id: A0A6J2M312
uniprot id: A0A6J2M778
uniprot id: A0A7E6E4H0
uniprot id: A0A7E6E530
uniprot id: A0A7E6E666
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglutaminase-like superfamily. PNGase family.
messages: Cytoplasm
messages: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.

89673:ARID1B
gene id: 89673:ARID1B
uniprot id: A0A6J2L9T3
names: Subcellular Location Annotation
messages: Nucleus

89673:TMEM200A
gene id: 89673:TMEM200A
uniprot id: A0A6J2LCX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

89673:FOXF1
gene id: 89673:FOXF1
uniprot id: A0A6J2KQG9
names: Subcellular Location Annotation
messages: Nucleus

89673:SNX1
gene id: 89673:SNX1
uniprot id: A0A6J2L405
uniprot id: A0A7E6CDY9
uniprot id: A0A7E6CFL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

89673:SLC4A9
gene id: 89673:SLC4A9
uniprot id: A0A6J2MVB9
uniprot id: A0A7E6CSH5
uniprot id: A0A7E6CSH7
uniprot id: A0A7E6CSI0
uniprot id: A0A7E6CSI3
uniprot id: A0A7E6CSZ2
uniprot id: A0A7E6CSZ4
uniprot id: A0A7E6CT73
uniprot id: A0A7E6CT79
uniprot id: A0A7E6CV87
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:SDHC
gene id: 89673:SDHC
uniprot id: A0A6J2KVH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

89673:SLC7A7
gene id: 89673:SLC7A7
uniprot id: A0A6J2LCJ1
names: Subcellular Location Annotation
messages: Membrane

89673:PTGER2
gene id: 89673:PTGER2
uniprot id: A0A6J2L5Z2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:SNX3
gene id: 89673:SNX3
uniprot id: A0A6J2LFK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome
messages: Endosome
messages: phagosome

89673:LOC114490797
gene id: 89673:LOC114490797
uniprot id: A0A7E6DCL9
names: Subcellular Location Annotation
messages: Nucleus

89673:CNEP1R1
gene id: 89673:CNEP1R1
uniprot id: A0A6J2KRB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNEP1R1 family.
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane

89673:LOC114498967
gene id: 89673:LOC114498967
uniprot id: A0A7E6E3E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Rough endoplasmic reticulum

89673:ENTPD5
gene id: 89673:ENTPD5
uniprot id: A0A6J2L887
uniprot id: A0A6J2LCW1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

89673:FIGN
gene id: 89673:FIGN
uniprot id: A0A6J2LFL9
uniprot id: A0A6J2LGQ5
names: Similarity
messages: Belongs to the AAA ATPase family.

89673:ACVR2A
gene id: 89673:ACVR2A
uniprot id: A0A6J2LEZ9
uniprot id: A0A6J2LJR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

89673:HNRNPH2
gene id: 89673:HNRNPH2
uniprot id: A0A6J2MDR8
names: Subcellular Location Annotation
messages: nucleoplasm

89673:LOC114491590
gene id: 89673:LOC114491590
uniprot id: A0A7E6E722
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

89673:OSBPL9
gene id: 89673:OSBPL9
uniprot id: A0A7E6DSK6
names: Similarity
messages: Belongs to the OSBP family.

89673:ERC1
gene id: 89673:ERC1
uniprot id: A0A6J2N4I8
uniprot id: A0A6J2N6B6
uniprot id: A0A6J2NB20
uniprot id: A0A7E6D515
uniprot id: A0A7E6D541
uniprot id: A0A7E6D570
uniprot id: A0A7E6D5Q6
uniprot id: A0A7E6D5R1
uniprot id: A0A7E6D7Y2
names: Subcellular Location Annotation
messages: Cytoplasm

89673:SLC4A3
gene id: 89673:SLC4A3
uniprot id: A0A6J2LH70
uniprot id: A0A6J2LJR4
uniprot id: A0A7E6DI25
uniprot id: A0A7E6DI62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

89673:CSRNP1
gene id: 89673:CSRNP1
uniprot id: A0A6J2M996
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

89673:ANXA13
gene id: 89673:ANXA13
uniprot id: A0A6J2NBG4
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

89673:DMRTB1
gene id: 89673:DMRTB1
uniprot id: A0A7E6DW37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

89673:LOC114503776
gene id: 89673:LOC114503776
uniprot id: A0A6J2MD41
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

89673:ATP5PF
gene id: 89673:ATP5PF
uniprot id: A0A6J2KWP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

89673:SDHAF2
gene id: 89673:SDHAF2
uniprot id: A0A6J2LYN7
uniprot id: A0A7E6E1K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with SDHA within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

89673:SLC10A2
gene id: 89673:SLC10A2
uniprot id: A0A6J2MTA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane
messages: Monomer and homodimer.

89673:HS3ST3B1
gene id: 89673:HS3ST3B1
uniprot id: A0A6J2NCT3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:BRCC3
gene id: 89673:BRCC3
uniprot id: A0A6J2MKS7
uniprot id: A0A7E6D010
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M67A family. BRCC36 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Component of the BRCA1-A complex. Component of the BRISC complex. Both the BRCA1-A complex and the BRISC complex bind polyubiquitin.
messages: Cytoplasm
messages: Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.
messages: Nucleus
messages: spindle pole

89673:LOC114500711
gene id: 89673:LOC114500711
uniprot id: A0A7E6DAI2
names: Subcellular Location Annotation
messages: Nucleus

89673:SMIM8
gene id: 89673:SMIM8
uniprot id: A0A7E6DMG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM8 family.
messages: Membrane

89673:YIPF6
gene id: 89673:YIPF6
uniprot id: A0A7E6D0G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

89673:RER1
gene id: 89673:RER1
uniprot id: A0A6J2LP13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

89673:LOC114489918
gene id: 89673:LOC114489918
uniprot id: A0A7E6D2Y2
uniprot id: A0A7E6D2Z4
uniprot id: A0A7E6D2Z9
uniprot id: A0A7E6D301
uniprot id: A0A7E6D3L2
uniprot id: A0A7E6D5M8
uniprot id: A0A7E6D5N9
names: Subcellular Location Annotation
messages: Nucleus

89673:LGSN
gene id: 89673:LGSN
uniprot id: A0A6J2LL82
uniprot id: A0A7E6DM35
uniprot id: A0A7E6DML5
uniprot id: A0A7E6DMW4
names: Similarity
messages: Belongs to the glutamine synthetase family.

89673:LOC114511454
gene id: 89673:LOC114511454
uniprot id: A0A7E6CPR3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:GALK1
gene id: 89673:GALK1
uniprot id: A0A6J2M8C7
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

89673:LOC118499679
gene id: 89673:LOC118499679
uniprot id: A0A7E6DEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

89673:DKK3
gene id: 89673:DKK3
uniprot id: A0A6J2LVK4
uniprot id: A0A6J2LZH8
uniprot id: A0A7E6E0B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

89673:LETM2
gene id: 89673:LETM2
uniprot id: A0A6J2MPK4
uniprot id: A0A6J2MVU7
names: Subcellular Location Annotation
messages: Membrane

89673:TMEM63B
gene id: 89673:TMEM63B
uniprot id: A0A6J2LA42
uniprot id: A0A6J2LBD0
uniprot id: A0A7E6DLP3
uniprot id: A0A7E6DM65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

89673:B4GALT4
gene id: 89673:B4GALT4
uniprot id: A0A6J2L0H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

89673:LOC114510843
gene id: 89673:LOC114510843
uniprot id: A0A7E6CQX4
names: Similarity
messages: Belongs to the MHC class I family.

89673:TMEM120B
gene id: 89673:TMEM120B
uniprot id: A0A6J2MU97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

89673:FAM76A
gene id: 89673:FAM76A
uniprot id: A0A6J2LQG0
names: Similarity
messages: Belongs to the FAM76 family.

89673:CD28
gene id: 89673:CD28
uniprot id: A0A6J2LE53
uniprot id: A0A7E6DIL0
uniprot id: A0A7E6DIS7
names: Subcellular Location Annotation
messages: Membrane

89673:TMEM150C
gene id: 89673:TMEM150C
uniprot id: A0A7E6DWR8
names: Subcellular Location Annotation
messages: Membrane

89673:CCSER2
gene id: 89673:CCSER2
uniprot id: A0A6J2LH68
uniprot id: A0A6J2LH76
uniprot id: A0A6J2LM57
uniprot id: A0A6J2LMV9
uniprot id: A0A7E6DTS5
uniprot id: A0A7E6DTY3
uniprot id: A0A7E6DUE6
uniprot id: A0A7E6DUR3
uniprot id: A0A7E6DV23
names: Similarity
messages: Belongs to the CCSER family.

89673:FDXR
gene id: 89673:FDXR
uniprot id: A0A6J2MDG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion
messages: Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

89673:BMP2
gene id: 89673:BMP2
uniprot id: A0A6J2MQM7
names: Similarity
messages: Belongs to the TGF-beta family.

89673:ISCA1
gene id: 89673:ISCA1
uniprot id: A0A6J2LTL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

89673:IER2
gene id: 89673:IER2
uniprot id: A0A6J2MDU9
names: Similarity
messages: Belongs to the IER family.

89673:SPTA1
gene id: 89673:SPTA1
uniprot id: A0A7E6CVK0
uniprot id: A0A7E6CVU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

89673:SNX25
gene id: 89673:SNX25
uniprot id: A0A7E6CL84
names: Similarity
messages: Belongs to the sorting nexin family.

89673:FAM160B2
gene id: 89673:FAM160B2
uniprot id: A0A6J2MBE7
names: Similarity
messages: Belongs to the FHIP family.

89673:TAX1BP3
gene id: 89673:TAX1BP3
uniprot id: A0A6J2NJE6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.
messages: Nucleus

89673:LOC114498895
gene id: 89673:LOC114498895
uniprot id: A0A6J2LUK7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114494267
gene id: 89673:LOC114494267
uniprot id: A0A6J2LG71
names: Similarity
messages: Belongs to the histone H3 family.

89673:LOC114490206
gene id: 89673:LOC114490206
uniprot id: A0A6J2L0W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RUNX1
gene id: 89673:RUNX1
uniprot id: A0A7E6D1I5
uniprot id: A0A7E6D2E2
uniprot id: A0A7E6D480
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

89673:XRN2
gene id: 89673:XRN2
uniprot id: A0A6J2MJ94
uniprot id: A0A7E6CED8
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

89673:LOC114491804
gene id: 89673:LOC114491804
uniprot id: A0A7E6DAD8
uniprot id: A0A7E6DAR2
uniprot id: A0A7E6DD56
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TMEM161B
gene id: 89673:TMEM161B
uniprot id: A0A6J2LZF2
uniprot id: A0A6J2M1I5
uniprot id: A0A7E6DAN4
uniprot id: A0A7E6DAR6
uniprot id: A0A7E6DB19
uniprot id: A0A7E6DD94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

89673:MARCKS
gene id: 89673:MARCKS
uniprot id: A0A6J2LEF2
names: Similarity
messages: Belongs to the MARCKS family.

89673:CXHXorf56
gene id: 89673:CXHXorf56
uniprot id: A0A6J2MLM0
names: Similarity
messages: Belongs to the STEEP1 family.

89673:LGALSL
gene id: 89673:LGALSL
uniprot id: A0A6J2LWI7
names: Function
messages: Does not bind lactose, and may not bind carbohydrates.

89673:POLG2
gene id: 89673:POLG2
uniprot id: A0A6J2MER0
uniprot id: A0A7E6EDI0
names: Subcellular Location Annotation
messages: Mitochondrion

89673:MPPED1
gene id: 89673:MPPED1
uniprot id: A0A6J2N9F6
names: Similarity
messages: Belongs to the UPF0046 family.

89673:DENND10
gene id: 89673:DENND10
uniprot id: A0A6J2LTP2
uniprot id: A0A6J2LTV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND10 family.
messages: Endosome
messages: Late endosome

89673:HSPA14
gene id: 89673:HSPA14
uniprot id: A0A6J2L6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Component of ribosome-associated complex (RAC), a heterodimer composed of Hsp70/DnaK-type chaperone HSPA14 and Hsp40/DnaJ-type chaperone DNAJC2.
messages: Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity.
messages: cytosol

89673:SYNJ1
gene id: 89673:SYNJ1
uniprot id: A0A7E6D1Z9
uniprot id: A0A7E6D203
uniprot id: A0A7E6D214
uniprot id: A0A7E6D218
uniprot id: A0A7E6D223
uniprot id: A0A7E6D250
uniprot id: A0A7E6D256
uniprot id: A0A7E6D2S1
uniprot id: A0A7E6D2S4
uniprot id: A0A7E6D4S9
uniprot id: A0A7E6D4T4
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

89673:PURG
gene id: 89673:PURG
uniprot id: A0A6J2MPZ2
uniprot id: A0A6J2MRT1
uniprot id: A0A6J2MW73
uniprot id: A0A7E6CKX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

89673:SF3B5
gene id: 89673:SF3B5
uniprot id: A0A6J2LII1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

89673:CHMP4C
gene id: 89673:CHMP4C
uniprot id: A0A6J2M7S2
names: Similarity
messages: Belongs to the SNF7 family.

89673:LOC114505677
gene id: 89673:LOC114505677
uniprot id: A0A7E6D0J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family.
messages: lamellipodium membrane
messages: ruffle membrane

89673:LOC114513384
gene id: 89673:LOC114513384
uniprot id: A0A6J2N999
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NOTCH1
gene id: 89673:NOTCH1
uniprot id: A0A6J2LIG0
uniprot id: A0A7E6DGW7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

89673:VSX1
gene id: 89673:VSX1
uniprot id: A0A6J2MN83
names: Subcellular Location Annotation
messages: Nucleus

89673:DDAH1
gene id: 89673:DDAH1
uniprot id: A0A6J2LQ74
uniprot id: A0A7E6DU00
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

89673:LOC114513050
gene id: 89673:LOC114513050
uniprot id: A0A7E6D9S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MAP3K10
gene id: 89673:MAP3K10
uniprot id: A0A6J2N0K7
uniprot id: A0A7E6CNR3
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

89673:LOC114512668
gene id: 89673:LOC114512668
uniprot id: A0A6J2N6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:SEMA6C
gene id: 89673:SEMA6C
uniprot id: A0A6J2KW33
uniprot id: A0A6J2KXU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114498470
gene id: 89673:LOC114498470
uniprot id: A0A6J2LR25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

89673:EXO1
gene id: 89673:EXO1
uniprot id: A0A7E6CYI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

89673:AVPR1A
gene id: 89673:AVPR1A
uniprot id: A0A6J2NBS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

89673:LOC114498900
gene id: 89673:LOC114498900
uniprot id: A0A6J2LUL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SDC2
gene id: 89673:SDC2
uniprot id: A0A6J2NCD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

89673:PVALB
gene id: 89673:PVALB
uniprot id: A0A6J2NA51
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

89673:GRK1
gene id: 89673:GRK1
uniprot id: A0A6J2MXS2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

89673:SLC37A4
gene id: 89673:SLC37A4
uniprot id: A0A6J2M1C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

89673:SLC25A5
gene id: 89673:SLC25A5
uniprot id: A0A6J2MG35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

89673:ADGRL2
gene id: 89673:ADGRL2
uniprot id: A0A7E6DSQ6
names: Subcellular Location Annotation
messages: Membrane

89673:TMEM229B
gene id: 89673:TMEM229B
uniprot id: A0A6J2L8G2
uniprot id: A0A6J2LA74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

89673:LOC114503700
gene id: 89673:LOC114503700
uniprot id: A0A7E6EAM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114492463
gene id: 89673:LOC114492463
uniprot id: A0A6J2L6Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

89673:COPS2
gene id: 89673:COPS2
uniprot id: A0A6J2L0V7
uniprot id: A0A6J2L569
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN2 family.
messages: Cytoplasm
messages: Nucleus

89673:ACOX1
gene id: 89673:ACOX1
uniprot id: A0A6J2M8J9
uniprot id: A0A6J2MBC2
uniprot id: A0A6J2MBY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

89673:KIF2B
gene id: 89673:KIF2B
uniprot id: A0A6J2ME17
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:SGPL1
gene id: 89673:SGPL1
uniprot id: A0A6J2LUB3
names: Similarity
messages: Belongs to the group II decarboxylase family.

89673:P2RX3
gene id: 89673:P2RX3
uniprot id: A0A6J2LZS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

89673:CELF1
gene id: 89673:CELF1
uniprot id: A0A6J2LUE6
uniprot id: A0A6J2LYR2
uniprot id: A0A7E6E161
uniprot id: A0A7E6E1N7
uniprot id: A0A7E6E1P2
uniprot id: A0A7E6E1V8
uniprot id: A0A7E6E2L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

89673:CDKL4
gene id: 89673:CDKL4
uniprot id: A0A6J2M234
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:PIPOX
gene id: 89673:PIPOX
uniprot id: A0A6J2MDP0
uniprot id: A0A7E6ED24
names: Similarity
messages: Belongs to the MSOX/MTOX family.

89673:IRF1
gene id: 89673:IRF1
uniprot id: A0A6J2N0S2
uniprot id: A0A7E6CUB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:NDUFB8
gene id: 89673:NDUFB8
uniprot id: A0A6J2LJB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:CCL17
gene id: 89673:CCL17
uniprot id: A0A6J2KX84
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

89673:EIF6
gene id: 89673:EIF6
uniprot id: A0A6J2MRS2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)-dependent protein kinase C activity. In tissues responsive to insulin, controls fatty acid synthesis and glycolysis by exerting translational control of adipogenic transcription factors such as CEBPB, CEBPD and ATF4 that have G/C rich or uORF in their 5'UTR. Required for ROS-dependent megakaryocyte maturation and platelets formation, controls the expression of mitochondrial respiratory chain genes involved in reactive oxygen species (ROS) synthesis. Involved in miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Modulates cell cycle progression and global translation of pre-B cells, its activation seems to be rate-limiting in tumorigenesis and tumor growth.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit. Interacts with RACK1. Interacts with DICER1, AGO2, TARBP2, MOV10 and RPL7A; they form a large RNA-induced silencing complex (RISC).
messages: Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.
messages: nucleolus

89673:PKP2
gene id: 89673:PKP2
uniprot id: A0A6J2NA90
uniprot id: A0A7E6D7S2
names: Similarity
messages: Belongs to the beta-catenin family.

89673:PPIH
gene id: 89673:PPIH
uniprot id: A0A6J2LMN1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:LOC114513492
gene id: 89673:LOC114513492
uniprot id: A0A6J2L142
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SF3B3
gene id: 89673:SF3B3
uniprot id: A0A6J2NFF9
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114507918
gene id: 89673:LOC114507918
uniprot id: A0A6J2MNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114510832
gene id: 89673:LOC114510832
uniprot id: A0A6J2MY52
names: Similarity
messages: Belongs to the MHC class I family.

89673:VPS4B
gene id: 89673:VPS4B
uniprot id: A0A6J2ML70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

89673:THAP1
gene id: 89673:THAP1
uniprot id: A0A6J2MSM8
uniprot id: A0A7E6CKJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: Interacts with PAWR. Component of a THAP1/THAP3-HCFC1-OGT complex that contains, either THAP1 or THAP3, HCFC1 and OGT. Interacts with OGT. Interacts (via the HBM) with HCFC1 (via the Kelch-repeat domain); the interaction recruits HCFC1 to the RRM1 promoter.
messages: nucleoplasm

89673:CDCA7L
gene id: 89673:CDCA7L
uniprot id: A0A7E6CJJ2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:RBM5
gene id: 89673:RBM5
uniprot id: A0A6J2M2D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

89673:GOLT1B
gene id: 89673:GOLT1B
uniprot id: A0A6J2NE51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

89673:LOC114495588
gene id: 89673:LOC114495588
uniprot id: A0A6J2LKY9
uniprot id: A0A7E6D973
uniprot id: A0A7E6D9A6
uniprot id: A0A7E6D9G7
uniprot id: A0A7E6DA56
names: Similarity
messages: Belongs to the peptidase C14A family.

89673:LOC118501655
gene id: 89673:LOC118501655
uniprot id: A0A7E6E672
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

89673:ARHGEF9
gene id: 89673:ARHGEF9
uniprot id: A0A6J2MEY6
uniprot id: A0A6J2MGP3
uniprot id: A0A6J2MGP7
uniprot id: A0A6J2MH25
uniprot id: A0A6J2MKB7
uniprot id: A0A6J2MKC4
uniprot id: A0A6J2MKX3
uniprot id: A0A7E6D102
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
messages: Cytoplasm
messages: Interacts with GPHN.
messages: Postsynaptic density

89673:PRUNE1
gene id: 89673:PRUNE1
uniprot id: A0A6J2KT71
uniprot id: A0A6J2KZ49
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

89673:LHFPL6
gene id: 89673:LHFPL6
uniprot id: A0A6J2MSS5
names: Subcellular Location Annotation
messages: Membrane

89673:CASQ2
gene id: 89673:CASQ2
uniprot id: A0A6J2KTU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

89673:DPH3
gene id: 89673:DPH3
uniprot id: A0A6J2M4A4
uniprot id: A0A6J2M7V5
names: Similarity
messages: Belongs to the DPH3 family.

89673:LOC114496226
gene id: 89673:LOC114496226
uniprot id: A0A6J2LHQ3
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:NUBPL
gene id: 89673:NUBPL
uniprot id: A0A6J2L7A9
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

89673:NDUFAF7
gene id: 89673:NDUFAF7
uniprot id: A0A6J2LWU8
uniprot id: A0A7E6DYE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

89673:BTD
gene id: 89673:BTD
uniprot id: A0A6J2M5Z1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

89673:MUSTN1
gene id: 89673:MUSTN1
uniprot id: A0A6J2M3E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

89673:LOC114503716
gene id: 89673:LOC114503716
uniprot id: A0A6J2MAR1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DESI2
gene id: 89673:DESI2
uniprot id: A0A6J2N554
uniprot id: A0A6J2N9R4
names: Similarity
messages: Belongs to the DeSI family.

89673:PIWIL2
gene id: 89673:PIWIL2
uniprot id: A0A6J2M960
names: Similarity
messages: Belongs to the argonaute family.

89673:PCNA
gene id: 89673:PCNA
uniprot id: A0A6J2MK55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

89673:LOC114499108
gene id: 89673:LOC114499108
uniprot id: A0A6J2LY06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

89673:PCMTD1
gene id: 89673:PCMTD1
uniprot id: A0A6J2M149
uniprot id: A0A6J2M3C1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

89673:SEPTIN9
gene id: 89673:SEPTIN9
uniprot id: A0A6J2MCD6
uniprot id: A0A7E6EFK8
uniprot id: A0A7E6EGC9
uniprot id: A0A7E6EGJ4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

89673:LOC114504807
gene id: 89673:LOC114504807
uniprot id: A0A7E6D2L3
names: Similarity
messages: Belongs to the HSBP1 family.

89673:PRND
gene id: 89673:PRND
uniprot id: A0A6J2MK92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prion family.
messages: Cell membrane
messages: Membrane

89673:HOXC10
gene id: 89673:HOXC10
uniprot id: A0A6J2N8J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

89673:CNTNAP2
gene id: 89673:CNTNAP2
uniprot id: A0A6J2MMN1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: paranodal septate junction

89673:SUGP1
gene id: 89673:SUGP1
uniprot id: A0A6J2MDU2
names: Subcellular Location Annotation
messages: Nucleus

89673:SPSB3
gene id: 89673:SPSB3
uniprot id: A0A6J2MI82
uniprot id: A0A6J2MI87
uniprot id: A0A7E6DC47
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

89673:MPP7
gene id: 89673:MPP7
uniprot id: A0A6J2L956
uniprot id: A0A6J2LD93
uniprot id: A0A7E6DHC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: adherens junction
messages: tight junction

89673:GABARAPL2
gene id: 89673:GABARAPL2
uniprot id: A0A6J2KR45
names: Similarity
messages: Belongs to the ATG8 family.

89673:LOC114500268
gene id: 89673:LOC114500268
uniprot id: A0A6J2LZE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SCAND1
gene id: 89673:SCAND1
uniprot id: A0A7E6CFX5
names: Subcellular Location Annotation
messages: Nucleus

89673:PRKCG
gene id: 89673:PRKCG
uniprot id: A0A6J2MZL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane

89673:VDAC3
gene id: 89673:VDAC3
uniprot id: A0A6J2MRW1
uniprot id: A0A6J2MWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
messages: Interacts with ARMC12 in a TBC1D21-dependent manner.
messages: Mitochondrion outer membrane

89673:SEC61A2
gene id: 89673:SEC61A2
uniprot id: A0A6J2L119
uniprot id: A0A6J2L4Q3
uniprot id: A0A7E6DM28
uniprot id: A0A7E6DMU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:PRKACB
gene id: 89673:PRKACB
uniprot id: A0A6J2LHN5
uniprot id: A0A6J2LHN9
uniprot id: A0A6J2LIW0
uniprot id: A0A6J2LIW4
uniprot id: A0A6J2LK08
uniprot id: A0A6J2LMK7
uniprot id: A0A6J2LNB4
uniprot id: A0A7E6DSV5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

89673:CFAP97D1
gene id: 89673:CFAP97D1
uniprot id: A0A6J2M6G8
uniprot id: A0A7E6EH25
names: Similarity
messages: Belongs to the CFAP97 family.

89673:NDUFB7
gene id: 89673:NDUFB7
uniprot id: A0A6J2MAX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

89673:HGH1
gene id: 89673:HGH1
uniprot id: A0A6J2NCD6
names: Similarity
messages: Belongs to the HGH1 family.

89673:ITPRIPL2
gene id: 89673:ITPRIPL2
uniprot id: A0A7E6DC71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

89673:PLBD1
gene id: 89673:PLBD1
uniprot id: A0A6J2NH88
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

89673:MCM9
gene id: 89673:MCM9
uniprot id: A0A6J2LAY6
uniprot id: A0A7E6DMY4
uniprot id: A0A7E6DNG3
uniprot id: A0A7E6DNL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

89673:ABCB11
gene id: 89673:ABCB11
uniprot id: A0A7E6DJI3
names: Subcellular Location Annotation
messages: Endosome

89673:ALG8
gene id: 89673:ALG8
uniprot id: A0A6J2M2T3
uniprot id: A0A7E6DZL7
uniprot id: A0A7E6E032
uniprot id: A0A7E6E0L9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:INHBC
gene id: 89673:INHBC
uniprot id: A0A6J2NGZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

89673:LOC114490123
gene id: 89673:LOC114490123
uniprot id: A0A6J2L2K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

89673:TSHZ3
gene id: 89673:TSHZ3
uniprot id: A0A7E6CQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

89673:LOC118497691
gene id: 89673:LOC118497691
uniprot id: A0A7E6CRT9
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114500314
gene id: 89673:LOC114500314
uniprot id: A0A6J2M3Z0
uniprot id: A0A7E6E1B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MTFR1L
gene id: 89673:MTFR1L
uniprot id: A0A6J2LIP1
uniprot id: A0A6J2LJZ1
uniprot id: A0A6J2LPC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

89673:OXSM
gene id: 89673:OXSM
uniprot id: A0A6J2M5L8
uniprot id: A0A7E6E536
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
messages: Mitochondrion

89673:ORAI1
gene id: 89673:ORAI1
uniprot id: A0A6J2MV43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

89673:ITGA2
gene id: 89673:ITGA2
uniprot id: A0A7E6D9P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:RPAIN
gene id: 89673:RPAIN
uniprot id: A0A6J2NFC3
uniprot id: A0A7E6ECP7
uniprot id: A0A7E6EDG5
names: Subcellular Location Annotation
messages: Nucleus

89673:RGR
gene id: 89673:RGR
uniprot id: A0A7E6DTT2
uniprot id: A0A7E6DUF1
names: Subcellular Location Annotation
messages: Membrane

89673:SNAP23
gene id: 89673:SNAP23
uniprot id: A0A6J2L8V6
uniprot id: A0A7E6E9W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

89673:RAF1
gene id: 89673:RAF1
uniprot id: A0A6J2M874
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

89673:CYSLTR1
gene id: 89673:CYSLTR1
uniprot id: A0A7E6CZK6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:SNURF
gene id: 89673:SNURF
uniprot id: A0A6J2KW78
names: Similarity
messages: Belongs to the SNURF family.

89673:CELF6
gene id: 89673:CELF6
uniprot id: A0A6J2L369
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

89673:LOC114508040
gene id: 89673:LOC114508040
uniprot id: A0A6J2MQP9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:LOC114497487
gene id: 89673:LOC114497487
uniprot id: A0A6J2LQ05
names: Subcellular Location Annotation
messages: Membrane

89673:TPRA1
gene id: 89673:TPRA1
uniprot id: A0A6J2MM59
uniprot id: A0A7E6CE73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

89673:ATP13A5
gene id: 89673:ATP13A5
uniprot id: A0A6J2L466
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:PIGS
gene id: 89673:PIGS
uniprot id: A0A6J2MCD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:CPLX2
gene id: 89673:CPLX2
uniprot id: A0A6J2N2P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

89673:LOC114491880
gene id: 89673:LOC114491880
uniprot id: A0A6J2L544
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

89673:MRPL33
gene id: 89673:MRPL33
uniprot id: A0A6J2LXL1
uniprot id: A0A7E6DXB5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

89673:TMEM59
gene id: 89673:TMEM59
uniprot id: A0A6J2LMH9
uniprot id: A0A6J2LSV2
uniprot id: A0A6J2LSX5
uniprot id: A0A7E6DSX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:TMEM199
gene id: 89673:TMEM199
uniprot id: A0A6J2M8M8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:RET
gene id: 89673:RET
uniprot id: A0A6J2LSV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.

89673:FBXO32
gene id: 89673:FBXO32
uniprot id: A0A6J2NB41
uniprot id: A0A7E6E8L0
names: Subcellular Location Annotation
messages: Nucleus

89673:ONECUT1
gene id: 89673:ONECUT1
uniprot id: A0A6J2LBJ3
uniprot id: A0A7E6EE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

89673:LOC114499058
gene id: 89673:LOC114499058
uniprot id: A0A7E6E3L1
names: Subcellular Location Annotation
messages: Membrane

89673:ANXA6
gene id: 89673:ANXA6
uniprot id: A0A6J2MUA6
uniprot id: A0A6J2N135
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

89673:SUFU
gene id: 89673:SUFU
uniprot id: A0A6J2LQH1
uniprot id: A0A6J2LUL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of GLI3 (GLI3FL). GLI3FL is complexed with SUFU in the cytoplasm and is maintained in a neutral state. Without the Hh signal, the SUFU-GLI3 complex is recruited to cilia, leading to the efficient processing of GLI3FL into GLI3R. When Hh signaling is initiated, SUFU dissociates from GLI3FL and the latter translocates to the nucleus, where it is phosphorylated, destabilized, and converted to a transcriptional activator (GLI3A).
messages: Nucleus

89673:ACADM
gene id: 89673:ACADM
uniprot id: A0A6J2LNH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Mitochondrion matrix

89673:SLC17A4
gene id: 89673:SLC17A4
uniprot id: A0A6J2KVJ8
names: Subcellular Location Annotation
messages: Membrane

89673:ADAM10
gene id: 89673:ADAM10
uniprot id: A0A6J2LDP2
uniprot id: A0A7E6EF67
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: adherens junction

89673:SULF1
gene id: 89673:SULF1
uniprot id: A0A6J2NCE8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

89673:CEP162
gene id: 89673:CEP162
uniprot id: A0A6J2LHY7
uniprot id: A0A7E6DMZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP162 family.
messages: centriole

89673:WNT8A
gene id: 89673:WNT8A
uniprot id: A0A7E6CXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:PALMD
gene id: 89673:PALMD
uniprot id: A0A6J2KUA9
names: Similarity
messages: Belongs to the paralemmin family.

89673:LOC114507471
gene id: 89673:LOC114507471
uniprot id: A0A6J2MSW5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:HMGN4
gene id: 89673:HMGN4
uniprot id: A0A7E6CXU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

89673:PM20D2
gene id: 89673:PM20D2
uniprot id: A0A6J2LHR4
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Catalyzes the peptide bond hydrolysis in dipeptides having basic amino acids lysine, ornithine or arginine at C-terminus.

89673:SLC45A3
gene id: 89673:SLC45A3
uniprot id: A0A6J2N8J5
names: Subcellular Location Annotation
messages: Membrane

89673:VNN2
gene id: 89673:VNN2
uniprot id: A0A6J2LH22
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

89673:NR4A3
gene id: 89673:NR4A3
uniprot id: A0A6J2M680
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

89673:XKR7
gene id: 89673:XKR7
uniprot id: A0A6J2MN44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

89673:INHBE
gene id: 89673:INHBE
uniprot id: A0A6J2NAI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

89673:MRPL34
gene id: 89673:MRPL34
uniprot id: A0A6J2MEA9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

89673:PTPRG
gene id: 89673:PTPRG
uniprot id: A0A6J2M860
uniprot id: A0A6J2M8T0
uniprot id: A0A7E6E811
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

89673:PAQR5
gene id: 89673:PAQR5
uniprot id: A0A6J2L5W8
uniprot id: A0A7E6CF80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

89673:VPS26C
gene id: 89673:VPS26C
uniprot id: A0A6J2L4B1
names: Similarity
messages: Belongs to the VPS26 family.

89673:KDELR3
gene id: 89673:KDELR3
uniprot id: A0A6J2N7A3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:SPIRE2
gene id: 89673:SPIRE2
uniprot id: A0A7E6CQE8
uniprot id: A0A7E6CQQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

89673:SLC35B4
gene id: 89673:SLC35B4
uniprot id: A0A6J2MUM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

89673:SLITRK2
gene id: 89673:SLITRK2
uniprot id: A0A6J2MHY4
names: Similarity
messages: Belongs to the SLITRK family.

89673:SKA1
gene id: 89673:SKA1
uniprot id: A0A7E6CH43
names: Similarity
messages: Belongs to the SKA1 family.

89673:MPP1
gene id: 89673:MPP1
uniprot id: A0A6J2MKU8
names: Function
names: Subcellular Location Annotation
messages: Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity.
messages: stereocilium

89673:LOC114492971
gene id: 89673:LOC114492971
uniprot id: A0A6J2LCV3
names: Subcellular Location Annotation
messages: Membrane

89673:EMG1
gene id: 89673:EMG1
uniprot id: A0A6J2NAB3
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

89673:TAF7L
gene id: 89673:TAF7L
uniprot id: A0A7E6CZC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

89673:CHRDL1
gene id: 89673:CHRDL1
uniprot id: A0A7E6D1F2
uniprot id: A0A7E6D274
uniprot id: A0A7E6D415
names: Subcellular Location Annotation
messages: Secreted

89673:NR4A2
gene id: 89673:NR4A2
uniprot id: A0A6J2LCE5
uniprot id: A0A7E6DJU6
uniprot id: A0A7E6DK42
uniprot id: A0A7E6DKA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Interacts with SFPQ, NCOR2, SIN3A and HADC1. The interaction with NCOR2 increases in the absence of PITX3. Interacts with PER2.
messages: Nucleus

89673:ZDHHC4
gene id: 89673:ZDHHC4
uniprot id: A0A6J2MXG8
uniprot id: A0A7E6CUS0
uniprot id: A0A7E6CVJ2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:LOC114509139
gene id: 89673:LOC114509139
uniprot id: A0A6J2MSH6
uniprot id: A0A7E6CUF6
uniprot id: A0A7E6CUF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

89673:UBXN1
gene id: 89673:UBXN1
uniprot id: A0A6J2LVL4
uniprot id: A0A7E6E2G5
names: Subcellular Location Annotation
messages: Cytoplasm

89673:ARF1
gene id: 89673:ARF1
uniprot id: A0A6J2NDV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

89673:SNRPN
gene id: 89673:SNRPN
uniprot id: A0A6J2L1J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

89673:LOC114501929
gene id: 89673:LOC114501929
uniprot id: A0A6J2M4Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

89673:NMT2
gene id: 89673:NMT2
uniprot id: A0A6J2L4I5
uniprot id: A0A6J2L6M0
uniprot id: A0A7E6DLI7
uniprot id: A0A7E6DLK0
uniprot id: A0A7E6DM04
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

89673:LOC114505487
gene id: 89673:LOC114505487
uniprot id: A0A6J2MIM3
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114498877
gene id: 89673:LOC114498877
uniprot id: A0A6J2LXI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ZDHHC21
gene id: 89673:ZDHHC21
uniprot id: A0A6J2M656
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:COG4
gene id: 89673:COG4
uniprot id: A0A6J2NJN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

89673:CENPI
gene id: 89673:CENPI
uniprot id: A0A6J2MH22
uniprot id: A0A7E6D3L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

89673:CCNO
gene id: 89673:CCNO
uniprot id: A0A6J2L591
names: Similarity
messages: Belongs to the cyclin family.

89673:ADAMTS12
gene id: 89673:ADAMTS12
uniprot id: A0A6J2M441
uniprot id: A0A7E6D9W5
uniprot id: A0A7E6DA08
uniprot id: A0A7E6DA82
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:C3H9orf78
gene id: 89673:C3H9orf78
uniprot id: A0A6J2MCI6
names: Similarity
messages: Belongs to the TLS1 family.

89673:HLF
gene id: 89673:HLF
uniprot id: A0A6J2MEF3
uniprot id: A0A6J2MHF1
uniprot id: A0A6J2MI96
uniprot id: A0A7E6EEZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

89673:LOC114499464
gene id: 89673:LOC114499464
uniprot id: A0A6J2LVT5
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

89673:ATP5IF1
gene id: 89673:ATP5IF1
uniprot id: A0A6J2LNI2
uniprot id: A0A6J2LSI3
uniprot id: A0A7E6DQL4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

89673:LOC114498933
gene id: 89673:LOC114498933
uniprot id: A0A6J2LY33
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CDKN3
gene id: 89673:CDKN3
uniprot id: A0A6J2L1Q4
uniprot id: A0A7E6CGD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
messages: perinuclear region

89673:LOC114495221
gene id: 89673:LOC114495221
uniprot id: A0A6J2LKB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

89673:SMPX
gene id: 89673:SMPX
uniprot id: A0A6J2MHJ8
names: Function
names: Similarity
messages: Belongs to the SMPX family.
messages: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.

89673:ACTN4
gene id: 89673:ACTN4
uniprot id: A0A6J2N1C7
uniprot id: A0A6J2N303
uniprot id: A0A6J2N315
uniprot id: A0A6J2N7N0
uniprot id: A0A6J2N8F6
names: Similarity
messages: Belongs to the alpha-actinin family.

89673:DUOX2
gene id: 89673:DUOX2
uniprot id: A0A6J2L7Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

89673:SPDYA
gene id: 89673:SPDYA
uniprot id: A0A6J2M2Q6
names: Similarity
messages: Belongs to the Speedy/Ringo family.

89673:RCAN2
gene id: 89673:RCAN2
uniprot id: A0A6J2LAX7
uniprot id: A0A6J2LGP0
names: Function
names: Similarity
messages: Belongs to the RCAN family.
messages: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

89673:EIF4ENIF1
gene id: 89673:EIF4ENIF1
uniprot id: A0A6J2MTS4
uniprot id: A0A6J2MTS6
uniprot id: A0A6J2MYS2
uniprot id: A0A7E6CRH3
names: Subcellular Location Annotation
messages: Cytoplasm

89673:HOXA3
gene id: 89673:HOXA3
uniprot id: A0A6J2MPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:RPS6KA1
gene id: 89673:RPS6KA1
uniprot id: A0A6J2LI62
uniprot id: A0A6J2LKJ0
uniprot id: A0A6J2LN43
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

89673:MYOD1
gene id: 89673:MYOD1
uniprot id: A0A6J2M185
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

89673:SMOC2
gene id: 89673:SMOC2
uniprot id: A0A7E6DNY4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RCL1
gene id: 89673:RCL1
uniprot id: A0A6J2MQS1
uniprot id: A0A7E6DEU9
uniprot id: A0A7E6DEZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.
messages: nucleolus

89673:MMP13
gene id: 89673:MMP13
uniprot id: A0A6J2M2N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CCN2. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
messages: Secreted

89673:ELP5
gene id: 89673:ELP5
uniprot id: A0A6J2NJ62
uniprot id: A0A7E6ECE0
uniprot id: A0A7E6ECH2
uniprot id: A0A7E6EDI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

89673:GDF9
gene id: 89673:GDF9
uniprot id: A0A6J2MXJ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

89673:LOC114495574
gene id: 89673:LOC114495574
uniprot id: A0A6J2LIC0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma. Interacts with palmitoylated calnexin (CALX), the interaction is required for efficient folding of glycosylated proteins.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

89673:RIMBP2
gene id: 89673:RIMBP2
uniprot id: A0A6J2KXK9
uniprot id: A0A6J2KZA4
uniprot id: A0A7E6CRT5
uniprot id: A0A7E6CRT6
uniprot id: A0A7E6CRT8
uniprot id: A0A7E6CS45
uniprot id: A0A7E6CS50
names: Similarity
messages: Belongs to the RIMBP family.

89673:HSD17B3
gene id: 89673:HSD17B3
uniprot id: A0A6J2N5W4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:CSNK2A1
gene id: 89673:CSNK2A1
uniprot id: A0A6J2MIZ5
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:IGFL4
gene id: 89673:IGFL4
uniprot id: A0A6J2N6K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IGFL family.
messages: Secreted

89673:G6PC
gene id: 89673:G6PC
uniprot id: A0A6J2MF15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

89673:NPC1
gene id: 89673:NPC1
uniprot id: A0A7E6CEA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

89673:LOC114505195
gene id: 89673:LOC114505195
uniprot id: A0A6J2MFR5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

89673:MRPS16
gene id: 89673:MRPS16
uniprot id: A0A6J2LMC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

89673:LOC114508583
gene id: 89673:LOC114508583
uniprot id: A0A6J2MWZ0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

89673:SEPTIN10
gene id: 89673:SEPTIN10
uniprot id: A0A6J2LLQ6
uniprot id: A0A7E6DTJ6
uniprot id: A0A7E6DTP5
uniprot id: A0A7E6DU65
uniprot id: A0A7E6DUT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

89673:ASPN
gene id: 89673:ASPN
uniprot id: A0A6J2NC43
uniprot id: A0A7E6D4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: extracellular matrix

89673:EIF5
gene id: 89673:EIF5
uniprot id: A0A6J2L244
names: Function
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).

89673:INO80
gene id: 89673:INO80
uniprot id: A0A7E6D4I1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

89673:TMEM33
gene id: 89673:TMEM33
uniprot id: A0A6J2L794
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

89673:DRGX
gene id: 89673:DRGX
uniprot id: A0A6J2LRA0
names: Subcellular Location Annotation
messages: Nucleus

89673:GATAD1
gene id: 89673:GATAD1
uniprot id: A0A6J2MTY4
names: Subcellular Location Annotation
messages: Nucleus

89673:SLITRK5
gene id: 89673:SLITRK5
uniprot id: A0A6J2MX45
names: Similarity
messages: Belongs to the SLITRK family.

89673:LOC114510840
gene id: 89673:LOC114510840
uniprot id: A0A6J2MY62
uniprot id: A0A7E6CQI5
names: Similarity
messages: Belongs to the MHC class I family.

89673:CHST6
gene id: 89673:CHST6
uniprot id: A0A6J2KT77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

89673:LOC114489155
gene id: 89673:LOC114489155
uniprot id: A0A7E6CVE9
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

89673:FFAR3
gene id: 89673:FFAR3
uniprot id: A0A6J2N8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

89673:LOC114500243
gene id: 89673:LOC114500243
uniprot id: A0A6J2M3Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SMAD9
gene id: 89673:SMAD9
uniprot id: A0A6J2MS69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

89673:H1-1
gene id: 89673:H1-1
uniprot id: A0A6J2KV03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

89673:CDK5
gene id: 89673:CDK5
uniprot id: A0A7E6CIY9
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:MARS2
gene id: 89673:MARS2
uniprot id: A0A6J2LB81
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

89673:LOC114497039
gene id: 89673:LOC114497039
uniprot id: A0A7E6DW01
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

89673:AKIRIN1
gene id: 89673:AKIRIN1
uniprot id: A0A6J2LNG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

89673:NDUFB2
gene id: 89673:NDUFB2
uniprot id: A0A6J2MVD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:LOC114497653
gene id: 89673:LOC114497653
uniprot id: A0A7E6DBJ2
names: Similarity
messages: Belongs to the RTRAF family.

89673:LOC114510722
gene id: 89673:LOC114510722
uniprot id: A0A7E6CQG1
names: Similarity
messages: Belongs to the MHC class I family.

89673:LOC114492816
gene id: 89673:LOC114492816
uniprot id: A0A6J2LAW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

89673:SV2B
gene id: 89673:SV2B
uniprot id: A0A6J2KS68
uniprot id: A0A7E6CSD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

89673:MARK2
gene id: 89673:MARK2
uniprot id: A0A6J2M0G2
uniprot id: A0A6J2M5Y9
uniprot id: A0A7E6E1U9
uniprot id: A0A7E6E2D4
uniprot id: A0A7E6E2J5
uniprot id: A0A7E6E387
uniprot id: A0A7E6E3A0
uniprot id: A0A7E6E3A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

89673:LOC114513262
gene id: 89673:LOC114513262
uniprot id: A0A6J2N8Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SGK2
gene id: 89673:SGK2
uniprot id: A0A6J2MKY9
uniprot id: A0A7E6CFI8
uniprot id: A0A7E6CG48
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:RTN1
gene id: 89673:RTN1
uniprot id: A0A6J2L9T2
uniprot id: A0A6J2LCQ9
uniprot id: A0A7E6CHL4
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TCTN2
gene id: 89673:TCTN2
uniprot id: A0A7E6CU08
uniprot id: A0A7E6CU15
uniprot id: A0A7E6CWU2
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

89673:LOC114497753
gene id: 89673:LOC114497753
uniprot id: A0A6J2LU73
uniprot id: A0A7E6DR04
names: Subcellular Location Annotation
messages: Membrane

89673:KHDRBS2
gene id: 89673:KHDRBS2
uniprot id: A0A6J2LDM5
names: Similarity
messages: Belongs to the KHDRBS family.

89673:GAST
gene id: 89673:GAST
uniprot id: A0A6J2M9K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
messages: Secreted

89673:FTO
gene id: 89673:FTO
uniprot id: A0A6J2KXC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

89673:ADH6
gene id: 89673:ADH6
uniprot id: A0A6J2L3P3
uniprot id: A0A7E6DSZ3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

89673:ANKRD13C
gene id: 89673:ANKRD13C
uniprot id: A0A6J2LMX9
names: Subcellular Location Annotation
messages: Membrane

89673:RBBP4
gene id: 89673:RBBP4
uniprot id: A0A6J2LJE6
names: Subcellular Location Annotation
messages: Nucleus

89673:PHAX
gene id: 89673:PHAX
uniprot id: A0A6J2M0R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

89673:LOC114491501
gene id: 89673:LOC114491501
uniprot id: A0A7E6CKH5
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

89673:GRK3
gene id: 89673:GRK3
uniprot id: A0A6J2MVT9
uniprot id: A0A7E6CUG0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

89673:ATAT1
gene id: 89673:ATAT1
uniprot id: A0A6J2LDG6
uniprot id: A0A6J2LEN5
uniprot id: A0A6J2LEN9
uniprot id: A0A6J2LI85
uniprot id: A0A7E6DKL3
uniprot id: A0A7E6DKL8
uniprot id: A0A7E6DKM4
uniprot id: A0A7E6DKX6
uniprot id: A0A7E6DL02
uniprot id: A0A7E6DLA2
uniprot id: A0A7E6DLB0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation strongly increases tubulin acetylation.
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Component of the BBSome complex. Interacts with AP2 alpha-adaptins, including AP2A2, but not with AP1 gamma-adaptin (AP1G1/AP1G2); this interaction is required for efficient alpha-tubulin acetylation, hence clathrin-coated pits are sites of microtubule acetylation.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

89673:PDE6H
gene id: 89673:PDE6H
uniprot id: A0A6J2NBQ9
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

89673:LOC114499591
gene id: 89673:LOC114499591
uniprot id: A0A6J2M0F2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:NSF
gene id: 89673:NSF
uniprot id: A0A7E6EEJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

89673:LOC118496670
gene id: 89673:LOC118496670
uniprot id: A0A7E6CD95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

89673:LOC114497994
gene id: 89673:LOC114497994
uniprot id: A0A6J2LV47
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MARVELD2
gene id: 89673:MARVELD2
uniprot id: A0A6J2N1I6
uniprot id: A0A7E6DBE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

89673:MARCHF9
gene id: 89673:MARCHF9
uniprot id: A0A6J2NFA3
names: Subcellular Location Annotation
messages: Membrane

89673:FMNL3
gene id: 89673:FMNL3
uniprot id: A0A6J2N6I0
uniprot id: A0A6J2N877
uniprot id: A0A6J2N8K4
uniprot id: A0A6J2NDS7
uniprot id: A0A7E6D6Q5
uniprot id: A0A7E6D6T0
uniprot id: A0A7E6D9M7
names: Similarity
messages: Belongs to the formin homology family.

89673:LOC114491563
gene id: 89673:LOC114491563
uniprot id: A0A7E6D7L9
uniprot id: A0A7E6D7T5
uniprot id: A0A7E6D7U1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

89673:NAT10
gene id: 89673:NAT10
uniprot id: A0A6J2LYR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with THUMPD1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

89673:LOC114498658
gene id: 89673:LOC114498658
uniprot id: A0A7E6E4B8
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

89673:LOC114491049
gene id: 89673:LOC114491049
uniprot id: A0A6J2L007
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TAF5
gene id: 89673:TAF5
uniprot id: A0A6J2LK98
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

89673:CENPN
gene id: 89673:CENPN
uniprot id: A0A7E6CRI0
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

89673:JRKL
gene id: 89673:JRKL
uniprot id: A0A6J2LRB2
names: Subcellular Location Annotation
messages: Nucleus

89673:MAN2C1
gene id: 89673:MAN2C1
uniprot id: A0A6J2L325
uniprot id: A0A7E6DWC3
uniprot id: A0A7E6DWD2
uniprot id: A0A7E6DWY8
uniprot id: A0A7E6DXB8
uniprot id: A0A7E6DXQ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

89673:THRB
gene id: 89673:THRB
uniprot id: A0A6J2M742
uniprot id: A0A7E6E749
uniprot id: A0A7E6E753
uniprot id: A0A7E6E7P5
uniprot id: A0A7E6E806
uniprot id: A0A7E6E8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

89673:P4HA1
gene id: 89673:P4HA1
uniprot id: A0A6J2LJK5
uniprot id: A0A6J2LKS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

89673:IFT122
gene id: 89673:IFT122
uniprot id: A0A6J2M1A8
uniprot id: A0A6J2M6Y0
uniprot id: A0A7E6E4Z7
uniprot id: A0A7E6E5M2
uniprot id: A0A7E6E5Q5
uniprot id: A0A7E6E6J3
uniprot id: A0A7E6E6N9
names: Subcellular Location Annotation
messages: cilium

89673:LUM
gene id: 89673:LUM
uniprot id: A0A6J2NF64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to laminin.
messages: extracellular matrix

89673:LOC114496890
gene id: 89673:LOC114496890
uniprot id: A0A7E6DRH2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

89673:KDM3A
gene id: 89673:KDM3A
uniprot id: A0A6J2LWF6
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114509853
gene id: 89673:LOC114509853
uniprot id: A0A6J2MX89
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:EFEMP2
gene id: 89673:EFEMP2
uniprot id: A0A6J2LUA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114497911
gene id: 89673:LOC114497911
uniprot id: A0A6J2LUW6
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.
messages: The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin.

89673:LOC114488279
gene id: 89673:LOC114488279
uniprot id: A0A6J2KUP2
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

89673:PDZK1IP1
gene id: 89673:PDZK1IP1
uniprot id: A0A6J2LN84
uniprot id: A0A7E6DRX6
names: Subcellular Location Annotation
messages: Membrane

89673:ACER3
gene id: 89673:ACER3
uniprot id: A0A6J2M259
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

89673:TRAPPC5
gene id: 89673:TRAPPC5
uniprot id: A0A6J2MTQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

89673:ERC2
gene id: 89673:ERC2
uniprot id: A0A6J2M325
uniprot id: A0A7E6E5F1
uniprot id: A0A7E6E5F5
uniprot id: A0A7E6E611
uniprot id: A0A7E6E616
uniprot id: A0A7E6E660
uniprot id: A0A7E6E664
uniprot id: A0A7E6E6Y5
uniprot id: A0A7E6E6Z2
uniprot id: A0A7E6E731
names: Subcellular Location Annotation
messages: Cytoplasm

89673:SNX20
gene id: 89673:SNX20
uniprot id: A0A6J2KUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

89673:ZNF622
gene id: 89673:ZNF622
uniprot id: A0A6J2MSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

89673:CCNYL1
gene id: 89673:CCNYL1
uniprot id: A0A6J2LGP7
uniprot id: A0A7E6DIG4
uniprot id: A0A7E6DIP7
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

89673:SCRN3
gene id: 89673:SCRN3
uniprot id: A0A6J2LIZ6
uniprot id: A0A7E6DJK5
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

89673:LOC114514370
gene id: 89673:LOC114514370
uniprot id: A0A6J2NA36
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

89673:TSG101
gene id: 89673:TSG101
uniprot id: A0A7E6E139
uniprot id: A0A7E6E1U1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

89673:ORMDL1
gene id: 89673:ORMDL1
uniprot id: A0A6J2LCK4
uniprot id: A0A7E6DJA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

89673:MAPRE2
gene id: 89673:MAPRE2
uniprot id: A0A6J2MJM0
uniprot id: A0A6J2MJZ5
uniprot id: A0A6J2MNS9
uniprot id: A0A7E6CDJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
messages: cytoskeleton

89673:LOC114490924
gene id: 89673:LOC114490924
uniprot id: A0A6J2L3Q9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:LOC114496342
gene id: 89673:LOC114496342
uniprot id: A0A6J2LN37
uniprot id: A0A7E6DFQ7
uniprot id: A0A7E6DFW7
names: Caution
names: Similarity
messages: Belongs to the MSANTD3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CAMSAP3
gene id: 89673:CAMSAP3
uniprot id: A0A6J2MUL1
uniprot id: A0A6J2MW83
uniprot id: A0A6J2N0U1
uniprot id: A0A7E6CSU4
uniprot id: A0A7E6CSV1
uniprot id: A0A7E6CSV3
uniprot id: A0A7E6CSV6
uniprot id: A0A7E6CTK8
uniprot id: A0A7E6CVL4
uniprot id: A0A7E6CVL9
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

89673:SLC16A9
gene id: 89673:SLC16A9
uniprot id: A0A6J2LNE0
names: Subcellular Location Annotation
messages: Membrane

89673:MAP7
gene id: 89673:MAP7
uniprot id: A0A6J2LDH2
uniprot id: A0A7E6DND4
uniprot id: A0A7E6DND9
uniprot id: A0A7E6DNF4
uniprot id: A0A7E6DNF9
uniprot id: A0A7E6DNU8
uniprot id: A0A7E6DP24
uniprot id: A0A7E6DP27
uniprot id: A0A7E6DPC5
uniprot id: A0A7E6DPD0
names: Similarity
messages: Belongs to the MAP7 family.

89673:LOC114502361
gene id: 89673:LOC114502361
uniprot id: A0A6J2M9R1
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

89673:LOC114489391
gene id: 89673:LOC114489391
uniprot id: A0A6J2KVA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:LOC114509078
gene id: 89673:LOC114509078
uniprot id: A0A7E6CVL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:SLC25A27
gene id: 89673:SLC25A27
uniprot id: A0A6J2LDW1
uniprot id: A0A6J2LGI0
uniprot id: A0A7E6DLS7
uniprot id: A0A7E6DM56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:PACSIN1
gene id: 89673:PACSIN1
uniprot id: A0A6J2LF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytosol
messages: ruffle membrane
messages: synaptosome

89673:KMT2D
gene id: 89673:KMT2D
uniprot id: A0A6J2N6X0
uniprot id: A0A7E6D6S5
uniprot id: A0A7E6D6T4
uniprot id: A0A7E6D6Z2
uniprot id: A0A7E6D6Z9
uniprot id: A0A7E6D7I1
uniprot id: A0A7E6D7I7
uniprot id: A0A7E6D9Q5
uniprot id: A0A7E6D9R0
names: Subcellular Location Annotation
messages: Nucleus

89673:SGCG
gene id: 89673:SGCG
uniprot id: A0A6J2MRP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: cytoskeleton
messages: sarcolemma

89673:CENPT
gene id: 89673:CENPT
uniprot id: A0A6J2KXE7
uniprot id: A0A7E6CLX8
uniprot id: A0A7E6CP55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus
messages: kinetochore

89673:GAS8
gene id: 89673:GAS8
uniprot id: A0A6J2KZ03
uniprot id: A0A7E6CQB4
uniprot id: A0A7E6CSV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum axoneme

89673:TFCP2L1
gene id: 89673:TFCP2L1
uniprot id: A0A6J2NBK5
uniprot id: A0A7E6DKI0
uniprot id: A0A7E6DKS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

89673:LOC114492127
gene id: 89673:LOC114492127
uniprot id: A0A6J2L7M2
names: Similarity
messages: Belongs to the serpin family.

89673:MAX
gene id: 89673:MAX
uniprot id: A0A6J2L1D4
uniprot id: A0A6J2L234
uniprot id: A0A6J2L3Q1
uniprot id: A0A6J2L6Z6
names: Similarity
messages: Belongs to the MAX family.

89673:BCAS2
gene id: 89673:BCAS2
uniprot id: A0A6J2KZ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

89673:SIM2
gene id: 89673:SIM2
uniprot id: A0A6J2KYY8
names: Subcellular Location Annotation
messages: Nucleus

89673:CENPX
gene id: 89673:CENPX
uniprot id: A0A6J2MHR1
uniprot id: A0A7E6EF11
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

89673:CDK5RAP1
gene id: 89673:CDK5RAP1
uniprot id: A0A6J2MLZ3
names: Similarity
messages: Belongs to the methylthiotransferase family. MiaB subfamily.

89673:LOC118500943
gene id: 89673:LOC118500943
uniprot id: A0A7E6DW42
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

89673:MT4
gene id: 89673:MT4
uniprot id: A0A6J2KUY1
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

89673:CA12
gene id: 89673:CA12
uniprot id: A0A6J2L931
uniprot id: A0A6J2LEA7
uniprot id: A0A7E6EFG9
uniprot id: A0A7E6EG13
uniprot id: A0A7E6EG23
uniprot id: A0A7E6EGB6
uniprot id: A0A7E6EH20
uniprot id: A0A7E6EHA7
uniprot id: A0A7E6EHB3
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

89673:LOC114489395
gene id: 89673:LOC114489395
uniprot id: A0A6J2L0N2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:TUBGCP2
gene id: 89673:TUBGCP2
uniprot id: A0A6J2LN89
uniprot id: A0A7E6DWG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

89673:LOC114491860
gene id: 89673:LOC114491860
uniprot id: A0A7E6DDZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

89673:TMED4
gene id: 89673:TMED4
uniprot id: A0A6J2KXM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114502747
gene id: 89673:LOC114502747
uniprot id: A0A6J2MBJ7
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:CARMIL3
gene id: 89673:CARMIL3
uniprot id: A0A6J2L7M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

89673:PLAC8L1
gene id: 89673:PLAC8L1
uniprot id: A0A6J2MX57
names: Similarity
messages: Belongs to the cornifelin family.

89673:SCUBE3
gene id: 89673:SCUBE3
uniprot id: A0A6J2LD53
uniprot id: A0A6J2LE38
uniprot id: A0A7E6DL70
uniprot id: A0A7E6DLK2
uniprot id: A0A7E6DLX8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:PRSS36
gene id: 89673:PRSS36
uniprot id: A0A6J2M6T7
uniprot id: A0A7E6DDX5
names: Function
names: Subcellular Location Annotation
messages: Serine protease. Has a preference for substrates with an Arg instead of a Lys residue in position P1.
messages: extracellular matrix

89673:DSTN
gene id: 89673:DSTN
uniprot id: A0A6J2MPK9
names: Function
names: Similarity
messages: Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.
messages: Belongs to the actin-binding proteins ADF family.

89673:SLC39A14
gene id: 89673:SLC39A14
uniprot id: A0A6J2M6C3
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114498984
gene id: 89673:LOC114498984
uniprot id: A0A7E6E3K7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

89673:KCNK10
gene id: 89673:KCNK10
uniprot id: A0A6J2L341
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

89673:LOC114497544
gene id: 89673:LOC114497544
uniprot id: A0A6J2LPA2
names: Similarity
names: Subunit
messages: Belongs to the SFTPD family.
messages: Oligomeric complex of 4 set of homotrimers.

89673:ARRDC5
gene id: 89673:ARRDC5
uniprot id: A0A6J2M8I7
names: Similarity
messages: Belongs to the arrestin family.

89673:LOC118499037
gene id: 89673:LOC118499037
uniprot id: A0A7E6D5U2
names: Similarity
messages: Belongs to the GroES chaperonin family.

89673:SKIL
gene id: 89673:SKIL
uniprot id: A0A6J2L010
names: Similarity
messages: Belongs to the SKI family.

89673:FECH
gene id: 89673:FECH
uniprot id: A0A6J2MII6
uniprot id: A0A7E6CGR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

89673:PAH
gene id: 89673:PAH
uniprot id: A0A6J2N832
uniprot id: A0A7E6D7Z3
uniprot id: A0A7E6DAV6
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

89673:LOC114513926
gene id: 89673:LOC114513926
uniprot id: A0A6J2NAX1
names: Similarity
messages: Belongs to the apolipoprotein L family.

89673:NMT1
gene id: 89673:NMT1
uniprot id: A0A6J2MEY0
uniprot id: A0A7E6EEA1
uniprot id: A0A7E6EG14
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

89673:GJD3
gene id: 89673:GJD3
uniprot id: A0A6J2MD14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:SOST
gene id: 89673:SOST
uniprot id: A0A6J2MC05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the sclerostin family.
messages: Interacts with LRP4 (via the extracellular domain); the interaction facilitates the inhibition of Wnt signaling. Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling. Interacts with LRP6.
messages: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

89673:DUT
gene id: 89673:DUT
uniprot id: A0A6J2L9G6
uniprot id: A0A7E6ECS9
uniprot id: A0A7E6EDI8
uniprot id: A0A7E6EDK0
uniprot id: A0A7E6EDK6
uniprot id: A0A7E6EDU6
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.