89152:KGNDJEFE RS05330
gene id: 89152:KGNDJEFE_RS05330
uniprot id: A0A856PY84
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS07475
gene id: 89152:KGNDJEFE_RS07475
uniprot id: A0A7T8V1Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

89152:KGNDJEFE RS09195
gene id: 89152:KGNDJEFE_RS09195
uniprot id: A0A856Q113
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

89152:KGNDJEFE RS08410
gene id: 89152:KGNDJEFE_RS08410
uniprot id: A0A7T8V4H5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

89152:KGNDJEFE RS03965
gene id: 89152:KGNDJEFE_RS03965
uniprot id: A0A856PX82
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

89152:KGNDJEFE RS09520
gene id: 89152:KGNDJEFE_RS09520
uniprot id: A0A856Q004
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

89152:KGNDJEFE RS10895
gene id: 89152:KGNDJEFE_RS10895
uniprot id: A0A7T8V3F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

89152:KGNDJEFE RS07245
gene id: 89152:KGNDJEFE_RS07245
uniprot id: A0A856PZ65
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

89152:KGNDJEFE RS08400
gene id: 89152:KGNDJEFE_RS08400
uniprot id: A0A856Q0K4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

89152:KGNDJEFE RS08015
gene id: 89152:KGNDJEFE_RS08015
uniprot id: A0A856Q0C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

89152:KGNDJEFE RS07315
gene id: 89152:KGNDJEFE_RS07315
uniprot id: A0A856Q0X2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

89152:KGNDJEFE RS00245
gene id: 89152:KGNDJEFE_RS00245
uniprot id: A0A856PW12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

89152:KGNDJEFE RS02915
gene id: 89152:KGNDJEFE_RS02915
uniprot id: A0A856PXB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS01850
gene id: 89152:KGNDJEFE_RS01850
uniprot id: A0A856PXM3
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

89152:KGNDJEFE RS04460
gene id: 89152:KGNDJEFE_RS04460
uniprot id: A0A856PY69
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

89152:KGNDJEFE RS10045
gene id: 89152:KGNDJEFE_RS10045
uniprot id: A0A856Q0W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

89152:KGNDJEFE RS09860
gene id: 89152:KGNDJEFE_RS09860
uniprot id: A0A856Q0L9
names: Similarity
messages: Belongs to the CvfB family.

89152:KGNDJEFE RS09995
gene id: 89152:KGNDJEFE_RS09995
uniprot id: A0A856Q0V3
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

89152:KGNDJEFE RS07445
gene id: 89152:KGNDJEFE_RS07445
uniprot id: A0A856PZA8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

89152:KGNDJEFE RS09135
gene id: 89152:KGNDJEFE_RS09135
uniprot id: A0A7T8ZR67
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

89152:KGNDJEFE RS02730
gene id: 89152:KGNDJEFE_RS02730
uniprot id: A0A856PX08
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

89152:KGNDJEFE RS00190
gene id: 89152:KGNDJEFE_RS00190
uniprot id: A0A7T8V3G4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

89152:KGNDJEFE RS08285
gene id: 89152:KGNDJEFE_RS08285
uniprot id: A0A856PZU2
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS03070
gene id: 89152:KGNDJEFE_RS03070
uniprot id: A0A856PX77
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

89152:KGNDJEFE RS03105
gene id: 89152:KGNDJEFE_RS03105
uniprot id: A0A7T8ZQ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

89152:KGNDJEFE RS04125
gene id: 89152:KGNDJEFE_RS04125
uniprot id: A0A856PXT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS00765
gene id: 89152:KGNDJEFE_RS00765
uniprot id: A0A856PW06
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

89152:KGNDJEFE RS09835
gene id: 89152:KGNDJEFE_RS09835
uniprot id: A0A856Q252
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

89152:KGNDJEFE RS08325
gene id: 89152:KGNDJEFE_RS08325
uniprot id: A0A856PZS3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS08860
gene id: 89152:KGNDJEFE_RS08860
uniprot id: A0A856PZN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

89152:KGNDJEFE RS11225
gene id: 89152:KGNDJEFE_RS11225
uniprot id: A0A856Q1J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

89152:KGNDJEFE RS08390
gene id: 89152:KGNDJEFE_RS08390
uniprot id: A0A856Q009
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

89152:KGNDJEFE RS02265
gene id: 89152:KGNDJEFE_RS02265
uniprot id: A0A7T8V2M6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

89152:KGNDJEFE RS11240
gene id: 89152:KGNDJEFE_RS11240
uniprot id: A0A7T8V3A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

89152:KGNDJEFE RS11295
gene id: 89152:KGNDJEFE_RS11295
uniprot id: A0A856Q1H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

89152:KGNDJEFE RS04020
gene id: 89152:KGNDJEFE_RS04020
uniprot id: A0A856PYZ1
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS09005
gene id: 89152:KGNDJEFE_RS09005
uniprot id: A0A856Q0A2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

89152:KGNDJEFE RS03315
gene id: 89152:KGNDJEFE_RS03315
uniprot id: A0A856PXI5
names: Similarity
messages: Belongs to the UPF0246 family.

89152:KGNDJEFE RS07130
gene id: 89152:KGNDJEFE_RS07130
uniprot id: A0A856PYQ9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

89152:KGNDJEFE RS06905
gene id: 89152:KGNDJEFE_RS06905
uniprot id: A0A856PYU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

89152:KGNDJEFE RS08670
gene id: 89152:KGNDJEFE_RS08670
uniprot id: A0A856PZJ8
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS08600
gene id: 89152:KGNDJEFE_RS08600
uniprot id: A0A856Q0P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

89152:KGNDJEFE RS07555
gene id: 89152:KGNDJEFE_RS07555
uniprot id: A0A856PZ80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

89152:KGNDJEFE RS09025
gene id: 89152:KGNDJEFE_RS09025
uniprot id: A0A856Q083
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

89152:KGNDJEFE RS02935
gene id: 89152:KGNDJEFE_RS02935
uniprot id: A0A856PWJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS10300
gene id: 89152:KGNDJEFE_RS10300
uniprot id: A0A856Q119
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

89152:KGNDJEFE RS04655
gene id: 89152:KGNDJEFE_RS04655
uniprot id: A0A856PXL7
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS02305
gene id: 89152:KGNDJEFE_RS02305
uniprot id: A0A856PWG5
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

89152:KGNDJEFE RS07030
gene id: 89152:KGNDJEFE_RS07030
uniprot id: A0A856PYP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

89152:KGNDJEFE RS00025
gene id: 89152:KGNDJEFE_RS00025
uniprot id: A0A856PVC4
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS00120
gene id: 89152:KGNDJEFE_RS00120
uniprot id: A0A7T8V3F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

89152:KGNDJEFE RS00420
gene id: 89152:KGNDJEFE_RS00420
uniprot id: A0A856PVI0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

89152:KGNDJEFE RS08145
gene id: 89152:KGNDJEFE_RS08145
uniprot id: A0A856PZM6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

89152:KGNDJEFE RS09910
gene id: 89152:KGNDJEFE_RS09910
uniprot id: A0A7T8ZR02
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

89152:KGNDJEFE RS04080
gene id: 89152:KGNDJEFE_RS04080
uniprot id: A0A856PX83
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

89152:KGNDJEFE RS09680
gene id: 89152:KGNDJEFE_RS09680
uniprot id: A0A7T8V3W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

89152:KGNDJEFE RS00970
gene id: 89152:KGNDJEFE_RS00970
uniprot id: A0A856PVL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

89152:KGNDJEFE RS09625
gene id: 89152:KGNDJEFE_RS09625
uniprot id: A0A856Q021
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS07400
gene id: 89152:KGNDJEFE_RS07400
uniprot id: A0A856PZF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS11310
gene id: 89152:KGNDJEFE_RS11310
uniprot id: A0A7T8V3K4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

89152:KGNDJEFE RS04135
gene id: 89152:KGNDJEFE_RS04135
uniprot id: A0A856PX46
names: Caution
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

89152:KGNDJEFE RS00150
gene id: 89152:KGNDJEFE_RS00150
uniprot id: A0A7T8ZQN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

89152:KGNDJEFE RS02640
gene id: 89152:KGNDJEFE_RS02640
uniprot id: A0A856PWH1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

89152:KGNDJEFE RS02655
gene id: 89152:KGNDJEFE_RS02655
uniprot id: A0A856PWN8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

89152:KGNDJEFE RS03075
gene id: 89152:KGNDJEFE_RS03075
uniprot id: A0A856PWN1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

89152:KGNDJEFE RS03285
gene id: 89152:KGNDJEFE_RS03285
uniprot id: A0A856PWP9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

89152:KGNDJEFE RS07055
gene id: 89152:KGNDJEFE_RS07055
uniprot id: A0A7T8ZQJ2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

89152:KGNDJEFE RS09885
gene id: 89152:KGNDJEFE_RS09885
uniprot id: A0A7T8V3U1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

89152:KGNDJEFE RS09710
gene id: 89152:KGNDJEFE_RS09710
uniprot id: A0A856Q1B3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS04625
gene id: 89152:KGNDJEFE_RS04625
uniprot id: A0A856PXJ3
names: Similarity
messages: Belongs to the TlyA family.

89152:KGNDJEFE RS04290
gene id: 89152:KGNDJEFE_RS04290
uniprot id: A0A7T8V289
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

89152:KGNDJEFE RS05840
gene id: 89152:KGNDJEFE_RS05840
uniprot id: A0A7T8V168
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

89152:KGNDJEFE RS01240
gene id: 89152:KGNDJEFE_RS01240
uniprot id: A0A7T8V2W7
names: Similarity
messages: Belongs to the YjdM family.

89152:KGNDJEFE RS07355
gene id: 89152:KGNDJEFE_RS07355
uniprot id: A0A856PZ50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

89152:KGNDJEFE RS08655
gene id: 89152:KGNDJEFE_RS08655
uniprot id: A0A856Q1M3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

89152:KGNDJEFE RS01825
gene id: 89152:KGNDJEFE_RS01825
uniprot id: A0A856PVY5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

89152:KGNDJEFE RS00065
gene id: 89152:KGNDJEFE_RS00065
uniprot id: A0A856PVD0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

89152:KGNDJEFE RS00115
gene id: 89152:KGNDJEFE_RS00115
uniprot id: A0A7T8V3G9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

89152:KGNDJEFE RS08815
gene id: 89152:KGNDJEFE_RS08815
uniprot id: A0A856Q019
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

89152:KGNDJEFE RS02285
gene id: 89152:KGNDJEFE_RS02285
uniprot id: A0A856PW68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

89152:KGNDJEFE RS09390
gene id: 89152:KGNDJEFE_RS09390
uniprot id: A0A856Q0L5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

89152:KGNDJEFE RS09065
gene id: 89152:KGNDJEFE_RS09065
uniprot id: A0A7T8ZQT0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

89152:KGNDJEFE RS00450
gene id: 89152:KGNDJEFE_RS00450
uniprot id: A0A856PX19
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

89152:KGNDJEFE RS09465
gene id: 89152:KGNDJEFE_RS09465
uniprot id: A0A856Q0J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

89152:KGNDJEFE RS07530
gene id: 89152:KGNDJEFE_RS07530
uniprot id: A0A856PYZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

89152:KGNDJEFE RS10450
gene id: 89152:KGNDJEFE_RS10450
uniprot id: A0A856Q151
names: Similarity
messages: Belongs to the SAICAR synthetase family.

89152:KGNDJEFE RS00255
gene id: 89152:KGNDJEFE_RS00255
uniprot id: A0A7T8V331
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

89152:KGNDJEFE RS08880
gene id: 89152:KGNDJEFE_RS08880
uniprot id: A0A856Q0B4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS09930
gene id: 89152:KGNDJEFE_RS09930
uniprot id: A0A856Q1F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

89152:KGNDJEFE RS11385
gene id: 89152:KGNDJEFE_RS11385
uniprot id: A0A856Q1G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

89152:KGNDJEFE RS01690
gene id: 89152:KGNDJEFE_RS01690
uniprot id: A0A856PW25
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

89152:KGNDJEFE RS00880
gene id: 89152:KGNDJEFE_RS00880
uniprot id: A0A7T8V313
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

89152:KGNDJEFE RS08310
gene id: 89152:KGNDJEFE_RS08310
uniprot id: A0A856Q0D0
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

89152:KGNDJEFE RS05300
gene id: 89152:KGNDJEFE_RS05300
uniprot id: A0A856PYI0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

89152:KGNDJEFE RS07045
gene id: 89152:KGNDJEFE_RS07045
uniprot id: A0A856PZ30
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS10100
gene id: 89152:KGNDJEFE_RS10100
uniprot id: A0A856Q0A7
names: Similarity
messages: Belongs to the DEAD box helicase family.

89152:KGNDJEFE RS09880
gene id: 89152:KGNDJEFE_RS09880
uniprot id: A0A856Q1E0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

89152:KGNDJEFE RS09035
gene id: 89152:KGNDJEFE_RS09035
uniprot id: A0A856Q012
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

89152:KGNDJEFE RS08320
gene id: 89152:KGNDJEFE_RS08320
uniprot id: A0A856PZC9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

89152:KGNDJEFE RS10720
gene id: 89152:KGNDJEFE_RS10720
uniprot id: A0A856Q1B6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

89152:KGNDJEFE RS04725
gene id: 89152:KGNDJEFE_RS04725
uniprot id: A0A856PXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS01695
gene id: 89152:KGNDJEFE_RS01695
uniprot id: A0A856PWJ2
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS04115
gene id: 89152:KGNDJEFE_RS04115
uniprot id: A0A856PXY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS11410
gene id: 89152:KGNDJEFE_RS11410
uniprot id: A0A856Q2J1
names: Similarity
messages: Belongs to the GSP E family.

89152:KGNDJEFE RS11615
gene id: 89152:KGNDJEFE_RS11615
uniprot id: A0A856Q1D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS03395
gene id: 89152:KGNDJEFE_RS03395
uniprot id: A0A7T8V277
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

89152:KGNDJEFE RS09600
gene id: 89152:KGNDJEFE_RS09600
uniprot id: A0A856Q195
names: Similarity
messages: Belongs to the transglycosylase Slt family.

89152:KGNDJEFE RS04525
gene id: 89152:KGNDJEFE_RS04525
uniprot id: A0A856PXH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

89152:KGNDJEFE RS01180
gene id: 89152:KGNDJEFE_RS01180
uniprot id: A0A7T8V377
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

89152:KGNDJEFE RS04185
gene id: 89152:KGNDJEFE_RS04185
uniprot id: A0A856PX56
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

89152:KGNDJEFE RS00275
gene id: 89152:KGNDJEFE_RS00275
uniprot id: A0A7T8V3D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

89152:KGNDJEFE RS07575
gene id: 89152:KGNDJEFE_RS07575
uniprot id: A0A856PZD3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

89152:KGNDJEFE RS04035
gene id: 89152:KGNDJEFE_RS04035
uniprot id: A0A856PX27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

89152:KGNDJEFE RS06075
gene id: 89152:KGNDJEFE_RS06075
uniprot id: A0A856PYJ7
names: Similarity
messages: Belongs to the PemK/MazF family.

89152:KGNDJEFE RS02955
gene id: 89152:KGNDJEFE_RS02955
uniprot id: A0A7T8ZQ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

89152:KGNDJEFE RS10465
gene id: 89152:KGNDJEFE_RS10465
uniprot id: A0A856Q0Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS00240
gene id: 89152:KGNDJEFE_RS00240
uniprot id: A0A7T8ZQE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

89152:KGNDJEFE RS01440
gene id: 89152:KGNDJEFE_RS01440
uniprot id: A0A856PWH3
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS00135
gene id: 89152:KGNDJEFE_RS00135
uniprot id: A0A7T8V371
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

89152:KGNDJEFE RS04565
gene id: 89152:KGNDJEFE_RS04565
uniprot id: A0A856PZ94
names: Similarity
messages: Belongs to the fabD family.

89152:KGNDJEFE RS07580
gene id: 89152:KGNDJEFE_RS07580
uniprot id: A0A856PZ02
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

89152:KGNDJEFE RS11395
gene id: 89152:KGNDJEFE_RS11395
uniprot id: A0A856Q1M6
names: Similarity
messages: Belongs to the peptidase A24 family.

89152:KGNDJEFE RS00760
gene id: 89152:KGNDJEFE_RS00760
uniprot id: A0A856PX31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

89152:KGNDJEFE RS03355
gene id: 89152:KGNDJEFE_RS03355
uniprot id: A0A856PX25
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS00260
gene id: 89152:KGNDJEFE_RS00260
uniprot id: A0A7T8V372
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

89152:KGNDJEFE RS00380
gene id: 89152:KGNDJEFE_RS00380
uniprot id: A0A856PVG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

89152:KGNDJEFE RS05835
gene id: 89152:KGNDJEFE_RS05835
uniprot id: A0A856PYF7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS01390
gene id: 89152:KGNDJEFE_RS01390
uniprot id: A0A856PWG4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS01650
gene id: 89152:KGNDJEFE_RS01650
uniprot id: A0A7T8V2T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

89152:KGNDJEFE RS10140
gene id: 89152:KGNDJEFE_RS10140
uniprot id: A0A856Q1D0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

89152:KGNDJEFE RS05885
gene id: 89152:KGNDJEFE_RS05885
uniprot id: A0A856PYG6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

89152:KGNDJEFE RS05745
gene id: 89152:KGNDJEFE_RS05745
uniprot id: A0A856PYY5
names: Similarity
messages: Belongs to the ThiD family.

89152:KGNDJEFE RS04580
gene id: 89152:KGNDJEFE_RS04580
uniprot id: A0A856PXC5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

89152:KGNDJEFE RS11520
gene id: 89152:KGNDJEFE_RS11520
uniprot id: A0A856Q1P3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

89152:KGNDJEFE RS04455
gene id: 89152:KGNDJEFE_RS04455
uniprot id: A0A856PXI2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

89152:KGNDJEFE RS06495
gene id: 89152:KGNDJEFE_RS06495
uniprot id: A0A856PYL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

89152:KGNDJEFE RS10885
gene id: 89152:KGNDJEFE_RS10885
uniprot id: A0A856Q2F1
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS11480
gene id: 89152:KGNDJEFE_RS11480
uniprot id: A0A856Q1H0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS06460
gene id: 89152:KGNDJEFE_RS06460
uniprot id: A0A856PYL0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS07625
gene id: 89152:KGNDJEFE_RS07625
uniprot id: A0A856PZE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

89152:KGNDJEFE RS06660
gene id: 89152:KGNDJEFE_RS06660
uniprot id: A0A856PYQ1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS03110
gene id: 89152:KGNDJEFE_RS03110
uniprot id: A0A856PXE8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

89152:KGNDJEFE RS01020
gene id: 89152:KGNDJEFE_RS01020
uniprot id: A0A7T8V375
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

89152:KGNDJEFE RS05770
gene id: 89152:KGNDJEFE_RS05770
uniprot id: A0A856PXY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

89152:KGNDJEFE RS07005
gene id: 89152:KGNDJEFE_RS07005
uniprot id: A0A856PYW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

89152:KGNDJEFE RS02235
gene id: 89152:KGNDJEFE_RS02235
uniprot id: A0A856PW59
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

89152:KGNDJEFE RS06025
gene id: 89152:KGNDJEFE_RS06025
uniprot id: A0A7T8V186
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS01995
gene id: 89152:KGNDJEFE_RS01995
uniprot id: A0A7T8V2N7
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

89152:KGNDJEFE RS01340
gene id: 89152:KGNDJEFE_RS01340
uniprot id: A0A856PVZ0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

89152:KGNDJEFE RS08840
gene id: 89152:KGNDJEFE_RS08840
uniprot id: A0A856Q0U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

89152:KGNDJEFE RS00220
gene id: 89152:KGNDJEFE_RS00220
uniprot id: A0A7T8ZQN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

89152:KGNDJEFE RS04120
gene id: 89152:KGNDJEFE_RS04120
uniprot id: A0A856PZ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

89152:KGNDJEFE RS00195
gene id: 89152:KGNDJEFE_RS00195
uniprot id: A0A7T8V3E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

89152:KGNDJEFE RS06780
gene id: 89152:KGNDJEFE_RS06780
uniprot id: A0A856PYJ5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS05255
gene id: 89152:KGNDJEFE_RS05255
uniprot id: A0A856PXY6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

89152:KGNDJEFE RS09150
gene id: 89152:KGNDJEFE_RS09150
uniprot id: A0A856Q0V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

89152:KGNDJEFE RS10530
gene id: 89152:KGNDJEFE_RS10530
uniprot id: A0A856Q0T6
names: Similarity
messages: Belongs to the peptidase M18 family.

89152:KGNDJEFE RS07075
gene id: 89152:KGNDJEFE_RS07075
uniprot id: A0A856PZ19
names: Similarity
messages: Belongs to the EamA transporter family.

89152:KGNDJEFE RS02405
gene id: 89152:KGNDJEFE_RS02405
uniprot id: A0A7T8V2T7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

89152:KGNDJEFE RS05210
gene id: 89152:KGNDJEFE_RS05210
uniprot id: A0A856PXP2
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

89152:KGNDJEFE RS07150
gene id: 89152:KGNDJEFE_RS07150
uniprot id: A0A7T8V1R9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS04275
gene id: 89152:KGNDJEFE_RS04275
uniprot id: A0A856PXC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS07270
gene id: 89152:KGNDJEFE_RS07270
uniprot id: A0A856PZP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

89152:KGNDJEFE RS10740
gene id: 89152:KGNDJEFE_RS10740
uniprot id: A0A856Q1M1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

89152:KGNDJEFE RS02775
gene id: 89152:KGNDJEFE_RS02775
uniprot id: A0A856PY83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS01090
gene id: 89152:KGNDJEFE_RS01090
uniprot id: A0A856PVX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

89152:KGNDJEFE RS04000
gene id: 89152:KGNDJEFE_RS04000
uniprot id: A0A856PXF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

89152:KGNDJEFE RS07525
gene id: 89152:KGNDJEFE_RS07525
uniprot id: A0A856PZC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

89152:KGNDJEFE RS08755
gene id: 89152:KGNDJEFE_RS08755
uniprot id: A0A856Q052
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

89152:KGNDJEFE RS01435
gene id: 89152:KGNDJEFE_RS01435
uniprot id: A0A856PW10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

89152:KGNDJEFE RS00205
gene id: 89152:KGNDJEFE_RS00205
uniprot id: A0A7T8V384
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

89152:KGNDJEFE RS06670
gene id: 89152:KGNDJEFE_RS06670
uniprot id: A0A7T8V1F8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS10715
gene id: 89152:KGNDJEFE_RS10715
uniprot id: A0A856Q175
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

89152:KGNDJEFE RS05240
gene id: 89152:KGNDJEFE_RS05240
uniprot id: A0A856PYN8
names: Similarity
messages: Belongs to the PRORSD1 family.

89152:KGNDJEFE RS09565
gene id: 89152:KGNDJEFE_RS09565
uniprot id: A0A7T8V493
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

89152:KGNDJEFE RS09480
gene id: 89152:KGNDJEFE_RS09480
uniprot id: A0A7T8V422
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

89152:KGNDJEFE RS06010
gene id: 89152:KGNDJEFE_RS06010
uniprot id: A0A856PYD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

89152:KGNDJEFE RS05920
gene id: 89152:KGNDJEFE_RS05920
uniprot id: A0A856PY15
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS08520
gene id: 89152:KGNDJEFE_RS08520
uniprot id: A0A856PZH1
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

89152:KGNDJEFE RS00945
gene id: 89152:KGNDJEFE_RS00945
uniprot id: A0A856PX63
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS02690
gene id: 89152:KGNDJEFE_RS02690
uniprot id: A0A856PWI1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

89152:KGNDJEFE RS06000
gene id: 89152:KGNDJEFE_RS06000
uniprot id: A0A856Q048
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

89152:KGNDJEFE RS01805
gene id: 89152:KGNDJEFE_RS01805
uniprot id: A0A856PWF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

89152:KGNDJEFE RS10565
gene id: 89152:KGNDJEFE_RS10565
uniprot id: A0A856Q107
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

89152:KGNDJEFE RS02005
gene id: 89152:KGNDJEFE_RS02005
uniprot id: A0A856PWJ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89152:KGNDJEFE RS04130
gene id: 89152:KGNDJEFE_RS04130
uniprot id: A0A856PX93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

89152:KGNDJEFE RS00250
gene id: 89152:KGNDJEFE_RS00250
uniprot id: A0A7T8V348
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

89152:KGNDJEFE RS02090
gene id: 89152:KGNDJEFE_RS02090
uniprot id: A0A856PW97
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

89152:KGNDJEFE RS02140
gene id: 89152:KGNDJEFE_RS02140
uniprot id: A0A856PWA7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS08560
gene id: 89152:KGNDJEFE_RS08560
uniprot id: A0A856Q0I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

89152:KGNDJEFE RS05190
gene id: 89152:KGNDJEFE_RS05190
uniprot id: A0A856PYM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

89152:KGNDJEFE RS05510
gene id: 89152:KGNDJEFE_RS05510
uniprot id: A0A856PXU2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS02660
gene id: 89152:KGNDJEFE_RS02660
uniprot id: A0A7T8ZQ12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

89152:KGNDJEFE RS10440
gene id: 89152:KGNDJEFE_RS10440
uniprot id: A0A7T8V3U3
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

89152:KGNDJEFE RS01035
gene id: 89152:KGNDJEFE_RS01035
uniprot id: A0A7T8V2Z1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

89152:KGNDJEFE RS08435
gene id: 89152:KGNDJEFE_RS08435
uniprot id: A0A856PZX0
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS11415
gene id: 89152:KGNDJEFE_RS11415
uniprot id: A0A7T8V3A5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

89152:KGNDJEFE RS10955
gene id: 89152:KGNDJEFE_RS10955
uniprot id: A0A856Q2F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS05495
gene id: 89152:KGNDJEFE_RS05495
uniprot id: A0A856PZV0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

89152:KGNDJEFE RS02645
gene id: 89152:KGNDJEFE_RS02645
uniprot id: A0A856PWD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Belongs to the RNase PH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

89152:KGNDJEFE RS03090
gene id: 89152:KGNDJEFE_RS03090
uniprot id: A0A7T8V2D2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

89152:KGNDJEFE RS10010
gene id: 89152:KGNDJEFE_RS10010
uniprot id: A0A856Q0P8
names: Similarity
messages: Belongs to the universal stress protein A family.

89152:KGNDJEFE RS09905
gene id: 89152:KGNDJEFE_RS09905
uniprot id: A0A7T8ZRL5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

89152:KGNDJEFE RS11315
gene id: 89152:KGNDJEFE_RS11315
uniprot id: A0A856Q2I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

89152:KGNDJEFE RS02060
gene id: 89152:KGNDJEFE_RS02060
uniprot id: A0A856PW40
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS08870
gene id: 89152:KGNDJEFE_RS08870
uniprot id: A0A856Q035
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS05645
gene id: 89152:KGNDJEFE_RS05645
uniprot id: A0A856PZX7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

89152:KGNDJEFE RS01410
gene id: 89152:KGNDJEFE_RS01410
uniprot id: A0A7T8V349
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

89152:KGNDJEFE RS02200
gene id: 89152:KGNDJEFE_RS02200
uniprot id: A0A856PWF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

89152:KGNDJEFE RS07265
gene id: 89152:KGNDJEFE_RS07265
uniprot id: A0A856Q0V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

89152:KGNDJEFE RS10250
gene id: 89152:KGNDJEFE_RS10250
uniprot id: A0A856Q109
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS01135
gene id: 89152:KGNDJEFE_RS01135
uniprot id: A0A856PVN5
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS09405
gene id: 89152:KGNDJEFE_RS09405
uniprot id: A0A856Q1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

89152:KGNDJEFE RS11285
gene id: 89152:KGNDJEFE_RS11285
uniprot id: A0A856Q1D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

89152:KGNDJEFE RS08885
gene id: 89152:KGNDJEFE_RS08885
uniprot id: A0A856PZY5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

89152:KGNDJEFE RS02260
gene id: 89152:KGNDJEFE_RS02260
uniprot id: A0A856PWC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

89152:KGNDJEFE RS01275
gene id: 89152:KGNDJEFE_RS01275
uniprot id: A0A856PVT3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

89152:KGNDJEFE RS02675
gene id: 89152:KGNDJEFE_RS02675
uniprot id: A0A7T8V2E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

89152:KGNDJEFE RS06855
gene id: 89152:KGNDJEFE_RS06855
uniprot id: A0A856PYT9
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS00740
gene id: 89152:KGNDJEFE_RS00740
uniprot id: A0A7T8V343
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

89152:KGNDJEFE RS11260
gene id: 89152:KGNDJEFE_RS11260
uniprot id: A0A7T8ZQR4
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

89152:KGNDJEFE RS07125
gene id: 89152:KGNDJEFE_RS07125
uniprot id: A0A856PZ29
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

89152:KGNDJEFE RS08000
gene id: 89152:KGNDJEFE_RS08000
uniprot id: A0A856PZN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

89152:KGNDJEFE RS04400
gene id: 89152:KGNDJEFE_RS04400
uniprot id: A0A856PXN8
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

89152:KGNDJEFE RS01365
gene id: 89152:KGNDJEFE_RS01365
uniprot id: A0A856PVV4
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

89152:KGNDJEFE RS11025
gene id: 89152:KGNDJEFE_RS11025
uniprot id: A0A7T8V3R0
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS09975
gene id: 89152:KGNDJEFE_RS09975
uniprot id: A0A856Q0H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

89152:KGNDJEFE RS04370
gene id: 89152:KGNDJEFE_RS04370
uniprot id: A0A856PXZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

89152:KGNDJEFE RS11495
gene id: 89152:KGNDJEFE_RS11495
uniprot id: A0A856Q1P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

89152:KGNDJEFE RS07440
gene id: 89152:KGNDJEFE_RS07440
uniprot id: A0A856PZ82
names: Similarity
messages: Belongs to the UPF0297 family.

89152:KGNDJEFE RS00030
gene id: 89152:KGNDJEFE_RS00030
uniprot id: A0A856PVK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

89152:KGNDJEFE RS02805
gene id: 89152:KGNDJEFE_RS02805
uniprot id: A0A856PWS9
names: Similarity
messages: Belongs to the EamA transporter family.

89152:KGNDJEFE RS08810
gene id: 89152:KGNDJEFE_RS08810
uniprot id: A0A856PZM5
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

89152:KGNDJEFE RS02320
gene id: 89152:KGNDJEFE_RS02320
uniprot id: A0A856PXY2
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

89152:KGNDJEFE RS08155
gene id: 89152:KGNDJEFE_RS08155
uniprot id: A0A856PZW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

89152:KGNDJEFE RS00900
gene id: 89152:KGNDJEFE_RS00900
uniprot id: A0A856PW24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

89152:KGNDJEFE RS10380
gene id: 89152:KGNDJEFE_RS10380
uniprot id: A0A856Q0Q9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

89152:KGNDJEFE RS05250
gene id: 89152:KGNDJEFE_RS05250
uniprot id: A0A856PYG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS04250
gene id: 89152:KGNDJEFE_RS04250
uniprot id: A0A7T8ZQP4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS10775
gene id: 89152:KGNDJEFE_RS10775
uniprot id: A0A856Q0Y6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

89152:KGNDJEFE RS07040
gene id: 89152:KGNDJEFE_RS07040
uniprot id: A0A856PYZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

89152:KGNDJEFE RS06640
gene id: 89152:KGNDJEFE_RS06640
uniprot id: A0A856PYS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

89152:KGNDJEFE RS10480
gene id: 89152:KGNDJEFE_RS10480
uniprot id: A0A856Q0S7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

89152:KGNDJEFE RS02905
gene id: 89152:KGNDJEFE_RS02905
uniprot id: A0A856PWT8
names: Similarity
messages: Belongs to the proline racemase family.

89152:KGNDJEFE RS04665
gene id: 89152:KGNDJEFE_RS04665
uniprot id: A0A856PZB6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

89152:KGNDJEFE RS09300
gene id: 89152:KGNDJEFE_RS09300
uniprot id: A0A7T8V4D9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

89152:KGNDJEFE RS01790
gene id: 89152:KGNDJEFE_RS01790
uniprot id: A0A7T8V2Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

89152:KGNDJEFE RS05980
gene id: 89152:KGNDJEFE_RS05980
uniprot id: A0A7T8V1B9
names: Similarity
messages: Belongs to the UPF0251 family.

89152:KGNDJEFE RS04480
gene id: 89152:KGNDJEFE_RS04480
uniprot id: A0A856PXA6
names: Similarity
messages: Belongs to the asp23 family.

89152:KGNDJEFE RS00890
gene id: 89152:KGNDJEFE_RS00890
uniprot id: A0A856PW72
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

89152:KGNDJEFE RS00985
gene id: 89152:KGNDJEFE_RS00985
uniprot id: A0A856PVT5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

89152:KGNDJEFE RS05320
gene id: 89152:KGNDJEFE_RS05320
uniprot id: A0A7T8ZRZ7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

89152:KGNDJEFE RS10350
gene id: 89152:KGNDJEFE_RS10350
uniprot id: A0A856Q132
names: Similarity
messages: Belongs to the BMP lipoprotein family.

89152:KGNDJEFE RS11035
gene id: 89152:KGNDJEFE_RS11035
uniprot id: A0A856Q1C9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS09640
gene id: 89152:KGNDJEFE_RS09640
uniprot id: A0A7T8V402
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

89152:KGNDJEFE RS06810
gene id: 89152:KGNDJEFE_RS06810
uniprot id: A0A856PZL0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS09550
gene id: 89152:KGNDJEFE_RS09550
uniprot id: A0A856Q186
names: Similarity
messages: Belongs to the UPF0758 family.

89152:KGNDJEFE RS03735
gene id: 89152:KGNDJEFE_RS03735
uniprot id: A0A856PX11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

89152:KGNDJEFE RS00210
gene id: 89152:KGNDJEFE_RS00210
uniprot id: A0A7T8V353
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

89152:KGNDJEFE RS09130
gene id: 89152:KGNDJEFE_RS09130
uniprot id: A0A856Q0G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

89152:KGNDJEFE RS09445
gene id: 89152:KGNDJEFE_RS09445
uniprot id: A0A856Q093
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

89152:KGNDJEFE RS01940
gene id: 89152:KGNDJEFE_RS01940
uniprot id: A0A856PW75
names: Similarity
messages: Belongs to the peptidase S58 family.

89152:KGNDJEFE RS10875
gene id: 89152:KGNDJEFE_RS10875
uniprot id: A0A7T8V3L1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

89152:KGNDJEFE RS08865
gene id: 89152:KGNDJEFE_RS08865
uniprot id: A0A7T8V4C7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

89152:KGNDJEFE RS04285
gene id: 89152:KGNDJEFE_RS04285
uniprot id: A0A7T8V203
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

89152:KGNDJEFE RS07235
gene id: 89152:KGNDJEFE_RS07235
uniprot id: A0A7T8V205
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

89152:KGNDJEFE RS02385
gene id: 89152:KGNDJEFE_RS02385
uniprot id: A0A7T8V2M0
names: Similarity
messages: Belongs to the CobH/CbiC family.

89152:KGNDJEFE RS01685
gene id: 89152:KGNDJEFE_RS01685
uniprot id: A0A856PW52
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

89152:KGNDJEFE RS08240
gene id: 89152:KGNDJEFE_RS08240
uniprot id: A0A856PZT1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS09585
gene id: 89152:KGNDJEFE_RS09585
uniprot id: A0A856Q0K0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

89152:KGNDJEFE RS02650
gene id: 89152:KGNDJEFE_RS02650
uniprot id: A0A856PWQ3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

89152:KGNDJEFE RS00400
gene id: 89152:KGNDJEFE_RS00400
uniprot id: A0A856PX09
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

89152:KGNDJEFE RS02980
gene id: 89152:KGNDJEFE_RS02980
uniprot id: A0A856PWK0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS00015
gene id: 89152:KGNDJEFE_RS00015
uniprot id: A0A856PVC6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

89152:KGNDJEFE RS10870
gene id: 89152:KGNDJEFE_RS10870
uniprot id: A0A856Q1E4
names: Similarity
messages: Belongs to the peptidase M18 family.

89152:KGNDJEFE RS04270
gene id: 89152:KGNDJEFE_RS04270
uniprot id: A0A856PXW5
names: Similarity
messages: Belongs to the threonine aldolase family.

89152:KGNDJEFE RS11280
gene id: 89152:KGNDJEFE_RS11280
uniprot id: A0A856Q0X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

89152:KGNDJEFE RS10755
gene id: 89152:KGNDJEFE_RS10755
uniprot id: A0A856Q144
names: Similarity
messages: Belongs to the SAICAR synthetase family.

89152:KGNDJEFE RS06915
gene id: 89152:KGNDJEFE_RS06915
uniprot id: A0A856Q0M8
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

89152:KGNDJEFE RS05875
gene id: 89152:KGNDJEFE_RS05875
uniprot id: A0A856PYB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

89152:KGNDJEFE RS04600
gene id: 89152:KGNDJEFE_RS04600
uniprot id: A0A856PXT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

89152:KGNDJEFE RS08740
gene id: 89152:KGNDJEFE_RS08740
uniprot id: A0A856Q0S2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

89152:KGNDJEFE RS00955
gene id: 89152:KGNDJEFE_RS00955
uniprot id: A0A856PVL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

89152:KGNDJEFE RS04100
gene id: 89152:KGNDJEFE_RS04100
uniprot id: A0A856PXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

89152:KGNDJEFE RS00045
gene id: 89152:KGNDJEFE_RS00045
uniprot id: A0A856PVX5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

89152:KGNDJEFE RS07495
gene id: 89152:KGNDJEFE_RS07495
uniprot id: A0A856PZB8
names: Similarity
messages: Belongs to the UPF0102 family.

89152:KGNDJEFE RS00350
gene id: 89152:KGNDJEFE_RS00350
uniprot id: A0A7T8V393
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

89152:KGNDJEFE RS02355
gene id: 89152:KGNDJEFE_RS02355
uniprot id: A0A856PWI4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

89152:KGNDJEFE RS09570
gene id: 89152:KGNDJEFE_RS09570
uniprot id: A0A7T8V413
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

89152:KGNDJEFE RS09085
gene id: 89152:KGNDJEFE_RS09085
uniprot id: A0A7T8V484
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

89152:KGNDJEFE RS10770
gene id: 89152:KGNDJEFE_RS10770
uniprot id: A0A856Q1C5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

89152:KGNDJEFE RS03020
gene id: 89152:KGNDJEFE_RS03020
uniprot id: A0A856PX67
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS09305
gene id: 89152:KGNDJEFE_RS09305
uniprot id: A0A856Q0Y2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

89152:KGNDJEFE RS02510
gene id: 89152:KGNDJEFE_RS02510
uniprot id: A0A856PWH7
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

89152:KGNDJEFE RS08920
gene id: 89152:KGNDJEFE_RS08920
uniprot id: A0A856Q045
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

89152:KGNDJEFE RS02835
gene id: 89152:KGNDJEFE_RS02835
uniprot id: A0A856PWH9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

89152:KGNDJEFE RS02505
gene id: 89152:KGNDJEFE_RS02505
uniprot id: A0A856PWL4
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS00005
gene id: 89152:KGNDJEFE_RS00005
uniprot id: A0A856PVQ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

89152:KGNDJEFE RS09645
gene id: 89152:KGNDJEFE_RS09645
uniprot id: A0A7T8V3Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

89152:KGNDJEFE RS02680
gene id: 89152:KGNDJEFE_RS02680
uniprot id: A0A856PWF1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

89152:KGNDJEFE RS06695
gene id: 89152:KGNDJEFE_RS06695
uniprot id: A0A856PYW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS08045
gene id: 89152:KGNDJEFE_RS08045
uniprot id: A0A856PZK8
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

89152:KGNDJEFE RS03740
gene id: 89152:KGNDJEFE_RS03740
uniprot id: A0A856PWX3
names: Similarity
messages: Belongs to the peptidase C40 family.

89152:KGNDJEFE RS03930
gene id: 89152:KGNDJEFE_RS03930
uniprot id: A0A856PXP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

89152:KGNDJEFE RS00080
gene id: 89152:KGNDJEFE_RS00080
uniprot id: A0A7T8ZQB2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

89152:KGNDJEFE RS00140
gene id: 89152:KGNDJEFE_RS00140
uniprot id: A0A7T8ZQP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

89152:KGNDJEFE RS03975
gene id: 89152:KGNDJEFE_RS03975
uniprot id: A0A856PYY0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS08525
gene id: 89152:KGNDJEFE_RS08525
uniprot id: A0A856PZW0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

89152:KGNDJEFE RS04540
gene id: 89152:KGNDJEFE_RS04540
uniprot id: A0A7T8ZQM5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

89152:KGNDJEFE RS01040
gene id: 89152:KGNDJEFE_RS01040
uniprot id: A0A856PX85
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

89152:KGNDJEFE RS10110
gene id: 89152:KGNDJEFE_RS10110
uniprot id: A0A856Q0R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

89152:KGNDJEFE RS07000
gene id: 89152:KGNDJEFE_RS07000
uniprot id: A0A856PZ66
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

89152:KGNDJEFE RS11320
gene id: 89152:KGNDJEFE_RS11320
uniprot id: A0A856Q1V6
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS10340
gene id: 89152:KGNDJEFE_RS10340
uniprot id: A0A856Q2A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

89152:KGNDJEFE RS02280
gene id: 89152:KGNDJEFE_RS02280
uniprot id: A0A856PW73
names: Similarity
messages: Belongs to the EamA transporter family.

89152:KGNDJEFE RS07050
gene id: 89152:KGNDJEFE_RS07050
uniprot id: A0A856PZ77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

89152:KGNDJEFE RS06705
gene id: 89152:KGNDJEFE_RS06705
uniprot id: A0A856PYR2
names: Similarity
messages: Belongs to the EamA transporter family.

89152:KGNDJEFE RS08805
gene id: 89152:KGNDJEFE_RS08805
uniprot id: A0A856Q061
names: Similarity
messages: Belongs to the class-I fumarase family.

89152:KGNDJEFE RS04855
gene id: 89152:KGNDJEFE_RS04855
uniprot id: A0A856PYF3
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS07570
gene id: 89152:KGNDJEFE_RS07570
uniprot id: A0A7T8V1X5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

89152:KGNDJEFE RS08875
gene id: 89152:KGNDJEFE_RS08875
uniprot id: A0A856Q055
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS05625
gene id: 89152:KGNDJEFE_RS05625
uniprot id: A0A856PYC2
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS09845
gene id: 89152:KGNDJEFE_RS09845
uniprot id: A0A856Q0S0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS02245
gene id: 89152:KGNDJEFE_RS02245
uniprot id: A0A856PW55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

89152:KGNDJEFE RS08255
gene id: 89152:KGNDJEFE_RS08255
uniprot id: A0A856Q0H6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

89152:KGNDJEFE RS10295
gene id: 89152:KGNDJEFE_RS10295
uniprot id: A0A856Q1F2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

89152:KGNDJEFE RS09455
gene id: 89152:KGNDJEFE_RS09455
uniprot id: A0A856Q204
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

89152:KGNDJEFE RS09580
gene id: 89152:KGNDJEFE_RS09580
uniprot id: A0A856Q0G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

89152:KGNDJEFE RS08665
gene id: 89152:KGNDJEFE_RS08665
uniprot id: A0A856Q028
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

89152:KGNDJEFE RS06055
gene id: 89152:KGNDJEFE_RS06055
uniprot id: A0A856PYX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

89152:KGNDJEFE RS10925
gene id: 89152:KGNDJEFE_RS10925
uniprot id: A0A7T8ZRE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

89152:KGNDJEFE RS03675
gene id: 89152:KGNDJEFE_RS03675
uniprot id: A0A856PYS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

89152:KGNDJEFE RS00170
gene id: 89152:KGNDJEFE_RS00170
uniprot id: A0A7T8V361
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

89152:KGNDJEFE RS11165
gene id: 89152:KGNDJEFE_RS11165
uniprot id: A0A856Q2G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

89152:KGNDJEFE RS06005
gene id: 89152:KGNDJEFE_RS06005
uniprot id: A0A856PYW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

89152:KGNDJEFE RS00165
gene id: 89152:KGNDJEFE_RS00165
uniprot id: A0A7T8V3H1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

89152:KGNDJEFE RS03265
gene id: 89152:KGNDJEFE_RS03265
uniprot id: A0A856PXH5
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS04405
gene id: 89152:KGNDJEFE_RS04405
uniprot id: A0A856PXH2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

89152:KGNDJEFE RS00745
gene id: 89152:KGNDJEFE_RS00745
uniprot id: A0A856PVP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

89152:KGNDJEFE RS02135
gene id: 89152:KGNDJEFE_RS02135
uniprot id: A0A856PWD8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS08510
gene id: 89152:KGNDJEFE_RS08510
uniprot id: A0A856Q0H2
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS06740
gene id: 89152:KGNDJEFE_RS06740
uniprot id: A0A856PYS2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

89152:KGNDJEFE RS09515
gene id: 89152:KGNDJEFE_RS09515
uniprot id: A0A7T8V3X9
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

89152:KGNDJEFE RS09590
gene id: 89152:KGNDJEFE_RS09590
uniprot id: A0A856Q0Q5
names: Similarity
messages: Belongs to the peptidase C40 family.

89152:KGNDJEFE RS11255
gene id: 89152:KGNDJEFE_RS11255
uniprot id: A0A856Q174
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS05775
gene id: 89152:KGNDJEFE_RS05775
uniprot id: A0A856PY97
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS00295
gene id: 89152:KGNDJEFE_RS00295
uniprot id: A0A7T8V338
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

89152:KGNDJEFE RS07310
gene id: 89152:KGNDJEFE_RS07310
uniprot id: A0A856PZX1
names: Similarity
messages: Belongs to the ribF family.

89152:KGNDJEFE RS11180
gene id: 89152:KGNDJEFE_RS11180
uniprot id: A0A856Q0W1
names: Similarity
messages: Belongs to the peptidase S41A family.

89152:KGNDJEFE RS02975
gene id: 89152:KGNDJEFE_RS02975
uniprot id: A0A856PWK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

89152:KGNDJEFE RS07485
gene id: 89152:KGNDJEFE_RS07485
uniprot id: A0A7T8V1L6
names: Similarity
messages: Belongs to the DprA/Smf family.

89152:KGNDJEFE RS00435
gene id: 89152:KGNDJEFE_RS00435
uniprot id: A0A856PVQ2
names: Similarity
messages: Belongs to the ycf81 family.

89152:KGNDJEFE RS00225
gene id: 89152:KGNDJEFE_RS00225
uniprot id: A0A856PVF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

89152:KGNDJEFE RS08075
gene id: 89152:KGNDJEFE_RS08075
uniprot id: A0A856Q075
names: Similarity
messages: Belongs to the CinA family.

89152:KGNDJEFE RS11100
gene id: 89152:KGNDJEFE_RS11100
uniprot id: A0A856Q1Z5
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

89152:KGNDJEFE RS09510
gene id: 89152:KGNDJEFE_RS09510
uniprot id: A0A856Q120
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS08125
gene id: 89152:KGNDJEFE_RS08125
uniprot id: A0A856Q085
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

89152:KGNDJEFE RS02535
gene id: 89152:KGNDJEFE_RS02535
uniprot id: A0A856PWC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

89152:KGNDJEFE RS08700
gene id: 89152:KGNDJEFE_RS08700
uniprot id: A0A856Q0R2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS04340
gene id: 89152:KGNDJEFE_RS04340
uniprot id: A0A856PXB2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

89152:KGNDJEFE RS08925
gene id: 89152:KGNDJEFE_RS08925
uniprot id: A0A856Q063
names: Similarity
messages: Belongs to the type IA topoisomerase family.

89152:KGNDJEFE RS01635
gene id: 89152:KGNDJEFE_RS01635
uniprot id: A0A856PW41
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

89152:KGNDJEFE RS00735
gene id: 89152:KGNDJEFE_RS00735
uniprot id: A0A7T8V536
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

89152:KGNDJEFE RS10760
gene id: 89152:KGNDJEFE_RS10760
uniprot id: A0A856Q145
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS08275
gene id: 89152:KGNDJEFE_RS08275
uniprot id: A0A856PZR7
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS02340
gene id: 89152:KGNDJEFE_RS02340
uniprot id: A0A856PWA6
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS01305
gene id: 89152:KGNDJEFE_RS01305
uniprot id: A0A856PXD5
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

89152:KGNDJEFE RS02620
gene id: 89152:KGNDJEFE_RS02620
uniprot id: A0A856PY59
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

89152:KGNDJEFE RS09095
gene id: 89152:KGNDJEFE_RS09095
uniprot id: A0A856Q1U0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

89152:KGNDJEFE RS02120
gene id: 89152:KGNDJEFE_RS02120
uniprot id: A0A856PW76
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

89152:KGNDJEFE RS03085
gene id: 89152:KGNDJEFE_RS03085
uniprot id: A0A856PWQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

89152:KGNDJEFE RS01425
gene id: 89152:KGNDJEFE_RS01425
uniprot id: A0A856PW45
names: Similarity
messages: Belongs to the peptidase M29 family.

89152:KGNDJEFE RS04530
gene id: 89152:KGNDJEFE_RS04530
uniprot id: A0A856PXB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

89152:KGNDJEFE RS00950
gene id: 89152:KGNDJEFE_RS00950
uniprot id: A0A856PW32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

89152:KGNDJEFE RS11515
gene id: 89152:KGNDJEFE_RS11515
uniprot id: A0A856Q1Z9
names: Similarity
messages: Belongs to the thymidylate kinase family.

89152:KGNDJEFE RS10275
gene id: 89152:KGNDJEFE_RS10275
uniprot id: A0A856Q131
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

89152:KGNDJEFE RS05910
gene id: 89152:KGNDJEFE_RS05910
uniprot id: A0A856PYU8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

89152:KGNDJEFE RS04605
gene id: 89152:KGNDJEFE_RS04605
uniprot id: A0A856PXK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

89152:KGNDJEFE RS03860
gene id: 89152:KGNDJEFE_RS03860
uniprot id: A0A856PX61
names: Subcellular Location Annotation
messages: Periplasm

89152:KGNDJEFE RS00230
gene id: 89152:KGNDJEFE_RS00230
uniprot id: A0A7T8ZQM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

89152:KGNDJEFE RS11325
gene id: 89152:KGNDJEFE_RS11325
uniprot id: A0A856Q1L5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

89152:KGNDJEFE RS09925
gene id: 89152:KGNDJEFE_RS09925
uniprot id: A0A856Q0G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

89152:KGNDJEFE RS10125
gene id: 89152:KGNDJEFE_RS10125
uniprot id: A0A856Q0K8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

89152:KGNDJEFE RS07305
gene id: 89152:KGNDJEFE_RS07305
uniprot id: A0A7T8V1J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

89152:KGNDJEFE RS10365
gene id: 89152:KGNDJEFE_RS10365
uniprot id: A0A856Q0X0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

89152:KGNDJEFE RS08595
gene id: 89152:KGNDJEFE_RS08595
uniprot id: A0A7T8V4H2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

89152:KGNDJEFE RS11565
gene id: 89152:KGNDJEFE_RS11565
uniprot id: A0A856Q1C6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

89152:KGNDJEFE RS01445
gene id: 89152:KGNDJEFE_RS01445
uniprot id: A0A856PXG7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS11055
gene id: 89152:KGNDJEFE_RS11055
uniprot id: A0A856Q1R1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

89152:KGNDJEFE RS07945
gene id: 89152:KGNDJEFE_RS07945
uniprot id: A0A856PZK3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

89152:KGNDJEFE RS00035
gene id: 89152:KGNDJEFE_RS00035
uniprot id: A0A856PVI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

89152:KGNDJEFE RS06470
gene id: 89152:KGNDJEFE_RS06470
uniprot id: A0A856Q0E5
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

89152:KGNDJEFE RS09755
gene id: 89152:KGNDJEFE_RS09755
uniprot id: A0A856Q0E1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

89152:KGNDJEFE RS02270
gene id: 89152:KGNDJEFE_RS02270
uniprot id: A0A856PXX0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

89152:KGNDJEFE RS09310
gene id: 89152:KGNDJEFE_RS09310
uniprot id: A0A856Q0G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

89152:KGNDJEFE RS00305
gene id: 89152:KGNDJEFE_RS00305
uniprot id: A0A7T8ZQM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

89152:KGNDJEFE RS09030
gene id: 89152:KGNDJEFE_RS09030
uniprot id: A0A7T8V450
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

89152:KGNDJEFE RS11030
gene id: 89152:KGNDJEFE_RS11030
uniprot id: A0A7T8V3E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

89152:KGNDJEFE RS00215
gene id: 89152:KGNDJEFE_RS00215
uniprot id: A0A7T8V363
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

89152:KGNDJEFE RS00920
gene id: 89152:KGNDJEFE_RS00920
uniprot id: A0A856PVK3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

89152:KGNDJEFE RS10105
gene id: 89152:KGNDJEFE_RS10105
uniprot id: A0A856Q0S5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

89152:KGNDJEFE RS09555
gene id: 89152:KGNDJEFE_RS09555
uniprot id: A0A856Q219
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

89152:KGNDJEFE RS05305
gene id: 89152:KGNDJEFE_RS05305
uniprot id: A0A856PXZ5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

89152:KGNDJEFE RS01680
gene id: 89152:KGNDJEFE_RS01680
uniprot id: A0A856PW69
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

89152:KGNDJEFE RS01055
gene id: 89152:KGNDJEFE_RS01055
uniprot id: A0A856PVN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

89152:KGNDJEFE RS01405
gene id: 89152:KGNDJEFE_RS01405
uniprot id: A0A856PVT8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

89152:KGNDJEFE RS02830
gene id: 89152:KGNDJEFE_RS02830
uniprot id: A0A856PX26
names: Similarity
messages: Belongs to the peptidase S11 family.

89152:KGNDJEFE RS01375
gene id: 89152:KGNDJEFE_RS01375
uniprot id: A0A856PW38
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS07520
gene id: 89152:KGNDJEFE_RS07520
uniprot id: A0A856PZV3
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

89152:KGNDJEFE RS02440
gene id: 89152:KGNDJEFE_RS02440
uniprot id: A0A856PWD7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

89152:KGNDJEFE RS11555
gene id: 89152:KGNDJEFE_RS11555
uniprot id: A0A856Q1L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

89152:KGNDJEFE RS03170
gene id: 89152:KGNDJEFE_RS03170
uniprot id: A0A856PYG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

89152:KGNDJEFE RS04375
gene id: 89152:KGNDJEFE_RS04375
uniprot id: A0A856PXE5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

89152:KGNDJEFE RS05845
gene id: 89152:KGNDJEFE_RS05845
uniprot id: A0A856PY91
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS02130
gene id: 89152:KGNDJEFE_RS02130
uniprot id: A0A856PWF0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS11420
gene id: 89152:KGNDJEFE_RS11420
uniprot id: A0A856Q1N1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS08475
gene id: 89152:KGNDJEFE_RS08475
uniprot id: A0A856PZV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

89152:KGNDJEFE RS00405
gene id: 89152:KGNDJEFE_RS00405
uniprot id: A0A7T8V3D1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

89152:KGNDJEFE RS00935
gene id: 89152:KGNDJEFE_RS00935
uniprot id: A0A856PVS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

89152:KGNDJEFE RS07025
gene id: 89152:KGNDJEFE_RS07025
uniprot id: A0A856PZ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

89152:KGNDJEFE RS05415
gene id: 89152:KGNDJEFE_RS05415
uniprot id: A0A856PY24
names: Similarity
messages: Belongs to the peptidase C59 family.

89152:KGNDJEFE RS02600
gene id: 89152:KGNDJEFE_RS02600
uniprot id: A0A856PWP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS04965
gene id: 89152:KGNDJEFE_RS04965
uniprot id: A0A7T8V4U1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

89152:KGNDJEFE RS01890
gene id: 89152:KGNDJEFE_RS01890
uniprot id: A0A7T8V2U0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

89152:KGNDJEFE RS03295
gene id: 89152:KGNDJEFE_RS03295
uniprot id: A0A7T8V284
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

89152:KGNDJEFE RS01880
gene id: 89152:KGNDJEFE_RS01880
uniprot id: A0A856PWA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

89152:KGNDJEFE RS00185
gene id: 89152:KGNDJEFE_RS00185
uniprot id: A0A7T8V3B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

89152:KGNDJEFE RS00410
gene id: 89152:KGNDJEFE_RS00410
uniprot id: A0A856PVH5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS09235
gene id: 89152:KGNDJEFE_RS09235
uniprot id: A0A856Q0I6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

89152:KGNDJEFE RS10195
gene id: 89152:KGNDJEFE_RS10195
uniprot id: A0A856Q1D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

89152:KGNDJEFE RS11560
gene id: 89152:KGNDJEFE_RS11560
uniprot id: A0A856Q1P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

89152:KGNDJEFE RS04230
gene id: 89152:KGNDJEFE_RS04230
uniprot id: A0A856PX66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

89152:KGNDJEFE RS02430
gene id: 89152:KGNDJEFE_RS02430
uniprot id: A0A7T8ZR11
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

89152:KGNDJEFE RS09575
gene id: 89152:KGNDJEFE_RS09575
uniprot id: A0A856Q0H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

89152:KGNDJEFE RS01875
gene id: 89152:KGNDJEFE_RS01875
uniprot id: A0A7T8V316
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

89152:KGNDJEFE RS09040
gene id: 89152:KGNDJEFE_RS09040
uniprot id: A0A856Q0Y1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

89152:KGNDJEFE RS00235
gene id: 89152:KGNDJEFE_RS00235
uniprot id: A0A7T8ZQA3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

89152:KGNDJEFE RS04245
gene id: 89152:KGNDJEFE_RS04245
uniprot id: A0A856PXK6
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

89152:KGNDJEFE RS09540
gene id: 89152:KGNDJEFE_RS09540
uniprot id: A0A856Q0P7
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

89152:KGNDJEFE RS01865
gene id: 89152:KGNDJEFE_RS01865
uniprot id: A0A7T8V2R5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

89152:KGNDJEFE RS11195
gene id: 89152:KGNDJEFE_RS11195
uniprot id: A0A856Q1F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

89152:KGNDJEFE RS06525
gene id: 89152:KGNDJEFE_RS06525
uniprot id: A0A856PZ79
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

89152:KGNDJEFE RS07345
gene id: 89152:KGNDJEFE_RS07345
uniprot id: A0A856PZ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

89152:KGNDJEFE RS00310
gene id: 89152:KGNDJEFE_RS00310
uniprot id: A0A7T8ZR96
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

89152:KGNDJEFE RS00160
gene id: 89152:KGNDJEFE_RS00160
uniprot id: A0A7T8ZQE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

89152:KGNDJEFE RS08225
gene id: 89152:KGNDJEFE_RS08225
uniprot id: A0A856PZT7
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS07295
gene id: 89152:KGNDJEFE_RS07295
uniprot id: A0A856PZ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

89152:KGNDJEFE RS11170
gene id: 89152:KGNDJEFE_RS11170
uniprot id: A0A856Q1S5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

89152:KGNDJEFE RS07330
gene id: 89152:KGNDJEFE_RS07330
uniprot id: A0A856PYV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

89152:KGNDJEFE RS00325
gene id: 89152:KGNDJEFE_RS00325
uniprot id: A0A7T8ZQD4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

89152:KGNDJEFE RS11595
gene id: 89152:KGNDJEFE_RS11595
uniprot id: A0A856Q1I4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

89152:KGNDJEFE RS07185
gene id: 89152:KGNDJEFE_RS07185
uniprot id: A0A856PZ44
names: Similarity
messages: Belongs to the FBPase class 3 family.

89152:KGNDJEFE RS00895
gene id: 89152:KGNDJEFE_RS00895
uniprot id: A0A856PX55
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

89152:KGNDJEFE RS10455
gene id: 89152:KGNDJEFE_RS10455
uniprot id: A0A856Q0H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

89152:KGNDJEFE RS02085
gene id: 89152:KGNDJEFE_RS02085
uniprot id: A0A856PWC6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

89152:KGNDJEFE RS07250
gene id: 89152:KGNDJEFE_RS07250
uniprot id: A0A856PZB5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS11020
gene id: 89152:KGNDJEFE_RS11020
uniprot id: A0A7T8ZQJ0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

89152:KGNDJEFE RS03985
gene id: 89152:KGNDJEFE_RS03985
uniprot id: A0A856PX20
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

89152:KGNDJEFE RS02300
gene id: 89152:KGNDJEFE_RS02300
uniprot id: A0A856PWI0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS01725
gene id: 89152:KGNDJEFE_RS01725
uniprot id: A0A856PVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

89152:KGNDJEFE RS10055
gene id: 89152:KGNDJEFE_RS10055
uniprot id: A0A856Q0R4
names: Similarity
messages: Belongs to the IMPACT family.

89152:KGNDJEFE RS11445
gene id: 89152:KGNDJEFE_RS11445
uniprot id: A0A7T8V3L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

89152:KGNDJEFE RS05050
gene id: 89152:KGNDJEFE_RS05050
uniprot id: A0A7T8V4U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

89152:KGNDJEFE RS04045
gene id: 89152:KGNDJEFE_RS04045
uniprot id: A0A856PX54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

89152:KGNDJEFE RS10265
gene id: 89152:KGNDJEFE_RS10265
uniprot id: A0A856Q0U8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS08135
gene id: 89152:KGNDJEFE_RS08135
uniprot id: A0A856PZ96
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

89152:KGNDJEFE RS09010
gene id: 89152:KGNDJEFE_RS09010
uniprot id: A0A856PZR1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

89152:KGNDJEFE RS09810
gene id: 89152:KGNDJEFE_RS09810
uniprot id: A0A856Q0L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS04610
gene id: 89152:KGNDJEFE_RS04610
uniprot id: A0A856PYA0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

89152:KGNDJEFE RS04165
gene id: 89152:KGNDJEFE_RS04165
uniprot id: A0A856PXZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

89152:KGNDJEFE RS00965
gene id: 89152:KGNDJEFE_RS00965
uniprot id: A0A7T8ZR75
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

89152:KGNDJEFE RS07790
gene id: 89152:KGNDJEFE_RS07790
uniprot id: A0A856PZI6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS08205
gene id: 89152:KGNDJEFE_RS08205
uniprot id: A0A7T8V4F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS08890
gene id: 89152:KGNDJEFE_RS08890
uniprot id: A0A856Q0V1
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS07635
gene id: 89152:KGNDJEFE_RS07635
uniprot id: A0A856PZD9
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS04105
gene id: 89152:KGNDJEFE_RS04105
uniprot id: A0A856PXH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

89152:KGNDJEFE RS09715
gene id: 89152:KGNDJEFE_RS09715
uniprot id: A0A856Q243
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

89152:KGNDJEFE RS06285
gene id: 89152:KGNDJEFE_RS06285
uniprot id: A0A856PYS4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS03150
gene id: 89152:KGNDJEFE_RS03150
uniprot id: A0A856PWY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

89152:KGNDJEFE RS06860
gene id: 89152:KGNDJEFE_RS06860
uniprot id: A0A856PZL9
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS02230
gene id: 89152:KGNDJEFE_RS02230
uniprot id: A0A856PW66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

89152:KGNDJEFE RS05580
gene id: 89152:KGNDJEFE_RS05580
uniprot id: A0A856PYD1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

89152:KGNDJEFE RS04840
gene id: 89152:KGNDJEFE_RS04840
uniprot id: A0A856PXX3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS11275
gene id: 89152:KGNDJEFE_RS11275
uniprot id: A0A856Q1K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

89152:KGNDJEFE RS07285
gene id: 89152:KGNDJEFE_RS07285
uniprot id: A0A856PZ62
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

89152:KGNDJEFE RS02365
gene id: 89152:KGNDJEFE_RS02365
uniprot id: A0A856PX03
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

89152:KGNDJEFE RS04305
gene id: 89152:KGNDJEFE_RS04305
uniprot id: A0A856PXF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

89152:KGNDJEFE RS01950
gene id: 89152:KGNDJEFE_RS01950
uniprot id: A0A856PXQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

89152:KGNDJEFE RS01045
gene id: 89152:KGNDJEFE_RS01045
uniprot id: A0A7T8ZR70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

89152:KGNDJEFE RS01835
gene id: 89152:KGNDJEFE_RS01835
uniprot id: A0A856PW80
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

89152:KGNDJEFE RS00370
gene id: 89152:KGNDJEFE_RS00370
uniprot id: A0A856PVH2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

89152:KGNDJEFE RS04310
gene id: 89152:KGNDJEFE_RS04310
uniprot id: A0A856PY31
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

89152:KGNDJEFE RS04780
gene id: 89152:KGNDJEFE_RS04780
uniprot id: A0A856PXP6
names: Similarity
messages: Belongs to the UPF0045 family.

89152:KGNDJEFE RS04205
gene id: 89152:KGNDJEFE_RS04205
uniprot id: A0A856PXK4
names: Subcellular Location Annotation
messages: Cytoplasm

89152:KGNDJEFE RS04585
gene id: 89152:KGNDJEFE_RS04585
uniprot id: A0A7T8V1V9
names: Similarity
messages: Belongs to the asp23 family.

89152:KGNDJEFE RS03365
gene id: 89152:KGNDJEFE_RS03365
uniprot id: A0A7T8ZQ69
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

89152:KGNDJEFE RS00100
gene id: 89152:KGNDJEFE_RS00100
uniprot id: A0A856PWU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

89152:KGNDJEFE RS04520
gene id: 89152:KGNDJEFE_RS04520
uniprot id: A0A856PY14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

89152:KGNDJEFE RS06165
gene id: 89152:KGNDJEFE_RS06165
uniprot id: A0A856PYH0
names: Similarity
messages: Belongs to the peptidase C40 family.

89152:KGNDJEFE RS11440
gene id: 89152:KGNDJEFE_RS11440
uniprot id: A0A856Q1J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

89152:KGNDJEFE RS08085
gene id: 89152:KGNDJEFE_RS08085
uniprot id: A0A856PZ87
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

89152:KGNDJEFE RS08230
gene id: 89152:KGNDJEFE_RS08230
uniprot id: A0A856PZQ8
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS00095
gene id: 89152:KGNDJEFE_RS00095
uniprot id: A0A856PVY4
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS09450
gene id: 89152:KGNDJEFE_RS09450
uniprot id: A0A856Q166
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

89152:KGNDJEFE RS00320
gene id: 89152:KGNDJEFE_RS00320
uniprot id: A0A7T8ZQ99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

89152:KGNDJEFE RS06690
gene id: 89152:KGNDJEFE_RS06690
uniprot id: A0A856PYR0
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS10270
gene id: 89152:KGNDJEFE_RS10270
uniprot id: A0A856Q0Y4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS07535
gene id: 89152:KGNDJEFE_RS07535
uniprot id: A0A856PZC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

89152:KGNDJEFE RS07480
gene id: 89152:KGNDJEFE_RS07480
uniprot id: A0A856PYY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

89152:KGNDJEFE RS00010
gene id: 89152:KGNDJEFE_RS00010
uniprot id: A0A7T8V379
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

89152:KGNDJEFE RS06600
gene id: 89152:KGNDJEFE_RS06600
uniprot id: A0A856PYV0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

89152:KGNDJEFE RS01895
gene id: 89152:KGNDJEFE_RS01895
uniprot id: A0A856PWN3
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

89152:KGNDJEFE RS10445
gene id: 89152:KGNDJEFE_RS10445
uniprot id: A0A856Q1I0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

89152:KGNDJEFE RS03390
gene id: 89152:KGNDJEFE_RS03390
uniprot id: A0A7T8V2F6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

89152:KGNDJEFE RS09735
gene id: 89152:KGNDJEFE_RS09735
uniprot id: A0A856Q0K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

89152:KGNDJEFE RS03815
gene id: 89152:KGNDJEFE_RS03815
uniprot id: A0A856PX47
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS11350
gene id: 89152:KGNDJEFE_RS11350
uniprot id: A0A856Q193
names: Similarity
messages: Belongs to the UDPGP type 2 family.

89152:KGNDJEFE RS09240
gene id: 89152:KGNDJEFE_RS09240
uniprot id: A0A856Q050
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

89152:KGNDJEFE RS02255
gene id: 89152:KGNDJEFE_RS02255
uniprot id: A0A856PWF4
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

89152:KGNDJEFE RS09675
gene id: 89152:KGNDJEFE_RS09675
uniprot id: A0A7T8V4A2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

89152:KGNDJEFE RS00445
gene id: 89152:KGNDJEFE_RS00445
uniprot id: A0A856PW48
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

89152:KGNDJEFE RS02375
gene id: 89152:KGNDJEFE_RS02375
uniprot id: A0A856PWT5
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

89152:KGNDJEFE RS06735
gene id: 89152:KGNDJEFE_RS06735
uniprot id: A0A856PYV2
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS00285
gene id: 89152:KGNDJEFE_RS00285
uniprot id: A0A856PVM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

89152:KGNDJEFE RS01385
gene id: 89152:KGNDJEFE_RS01385
uniprot id: A0A856PW01
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS08405
gene id: 89152:KGNDJEFE_RS08405
uniprot id: A0A856Q1I5
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

89152:KGNDJEFE RS04550
gene id: 89152:KGNDJEFE_RS04550
uniprot id: A0A856PXS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

89152:KGNDJEFE RS08355
gene id: 89152:KGNDJEFE_RS08355
uniprot id: A0A856Q1H7
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

89152:KGNDJEFE RS02205
gene id: 89152:KGNDJEFE_RS02205
uniprot id: A0A856PWE4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS09685
gene id: 89152:KGNDJEFE_RS09685
uniprot id: A0A856Q0I9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

89152:KGNDJEFE RS04435
gene id: 89152:KGNDJEFE_RS04435
uniprot id: A0A856PXH6
names: Similarity
messages: Belongs to the UPF0145 family.

89152:KGNDJEFE RS03415
gene id: 89152:KGNDJEFE_RS03415
uniprot id: A0A856PXK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

89152:KGNDJEFE RS11540
gene id: 89152:KGNDJEFE_RS11540
uniprot id: A0A856Q121
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

89152:KGNDJEFE RS04620
gene id: 89152:KGNDJEFE_RS04620
uniprot id: A0A856PY35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

89152:KGNDJEFE RS04040
gene id: 89152:KGNDJEFE_RS04040
uniprot id: A0A856PX94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

89152:KGNDJEFE RS05935
gene id: 89152:KGNDJEFE_RS05935
uniprot id: A0A7T8V1C5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS10850
gene id: 89152:KGNDJEFE_RS10850
uniprot id: A0A856Q0Q0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

89152:KGNDJEFE RS07010
gene id: 89152:KGNDJEFE_RS07010
uniprot id: A0A856PZP6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS10035
gene id: 89152:KGNDJEFE_RS10035
uniprot id: A0A856Q270
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

89152:KGNDJEFE RS00460
gene id: 89152:KGNDJEFE_RS00460
uniprot id: A0A856PVI5
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

89152:KGNDJEFE RS07430
gene id: 89152:KGNDJEFE_RS07430
uniprot id: A0A7T8V1L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

89152:KGNDJEFE RS09850
gene id: 89152:KGNDJEFE_RS09850
uniprot id: A0A856Q059
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

89152:KGNDJEFE RS07260
gene id: 89152:KGNDJEFE_RS07260
uniprot id: A0A856PZU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

89152:KGNDJEFE RS01855
gene id: 89152:KGNDJEFE_RS01855
uniprot id: A0A856PWG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

89152:KGNDJEFE RS04675
gene id: 89152:KGNDJEFE_RS04675
uniprot id: A0A7T8V1N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

89152:KGNDJEFE RS02345
gene id: 89152:KGNDJEFE_RS02345
uniprot id: A0A856PW74
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

89152:KGNDJEFE RS03465
gene id: 89152:KGNDJEFE_RS03465
uniprot id: A0A856PXL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

89152:KGNDJEFE RS11230
gene id: 89152:KGNDJEFE_RS11230
uniprot id: A0A856Q0W7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

89152:KGNDJEFE RS08175
gene id: 89152:KGNDJEFE_RS08175
uniprot id: A0A856Q099
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

89152:KGNDJEFE RS08590
gene id: 89152:KGNDJEFE_RS08590
uniprot id: A0A856Q049
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

89152:KGNDJEFE RS02095
gene id: 89152:KGNDJEFE_RS02095
uniprot id: A0A856PWT3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

89152:KGNDJEFE RS01765
gene id: 89152:KGNDJEFE_RS01765
uniprot id: A0A856PVX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

89152:KGNDJEFE RS04950
gene id: 89152:KGNDJEFE_RS04950
uniprot id: A0A856PYH6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

89152:KGNDJEFE RS00960
gene id: 89152:KGNDJEFE_RS00960
uniprot id: A0A856PVL8
names: Similarity
messages: Belongs to the ParB family.

89152:KGNDJEFE RS06435
gene id: 89152:KGNDJEFE_RS06435
uniprot id: A0A856PYC4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

89152:KGNDJEFE RS00925
gene id: 89152:KGNDJEFE_RS00925
uniprot id: A0A856PVV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

89152:KGNDJEFE RS09315
gene id: 89152:KGNDJEFE_RS09315
uniprot id: A0A856PZW5
names: Similarity
messages: Belongs to the RecJ family.

89152:KGNDJEFE RS11175
gene id: 89152:KGNDJEFE_RS11175
uniprot id: A0A856Q1I9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

89152:KGNDJEFE RS01060
gene id: 89152:KGNDJEFE_RS01060
uniprot id: A0A7T8ZQA2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

89152:KGNDJEFE RS02630
gene id: 89152:KGNDJEFE_RS02630
uniprot id: A0A7T8V1B7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

89152:KGNDJEFE RS04985
gene id: 89152:KGNDJEFE_RS04985
uniprot id: A0A856PY20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS03370
gene id: 89152:KGNDJEFE_RS03370
uniprot id: A0A856PYK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

89152:KGNDJEFE RS00085
gene id: 89152:KGNDJEFE_RS00085
uniprot id: A0A7T8ZQF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

89152:KGNDJEFE RS00180
gene id: 89152:KGNDJEFE_RS00180
uniprot id: A0A7T8V383
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

89152:KGNDJEFE RS03760
gene id: 89152:KGNDJEFE_RS03760
uniprot id: A0A856PXB1
names: Similarity
messages: Belongs to the peptidase C40 family.

89152:KGNDJEFE RS04215
gene id: 89152:KGNDJEFE_RS04215
uniprot id: A0A856PY11
names: Similarity
messages: Belongs to the EamA transporter family.

89152:KGNDJEFE RS07590
gene id: 89152:KGNDJEFE_RS07590
uniprot id: A0A856PZB1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

89152:KGNDJEFE RS08430
gene id: 89152:KGNDJEFE_RS08430
uniprot id: A0A856PZT5
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS04110
gene id: 89152:KGNDJEFE_RS04110
uniprot id: A0A856PXA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

89152:KGNDJEFE RS06060
gene id: 89152:KGNDJEFE_RS06060
uniprot id: A0A856PYE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

89152:KGNDJEFE RS09530
gene id: 89152:KGNDJEFE_RS09530
uniprot id: A0A856Q0F9
names: Similarity
messages: Belongs to the transpeptidase family.

89152:KGNDJEFE RS07240
gene id: 89152:KGNDJEFE_RS07240
uniprot id: A0A856PZ32
names: Cofactor
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

89152:KGNDJEFE RS10150
gene id: 89152:KGNDJEFE_RS10150
uniprot id: A0A856Q0B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS03720
gene id: 89152:KGNDJEFE_RS03720
uniprot id: A0A856PXR2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

89152:KGNDJEFE RS00440
gene id: 89152:KGNDJEFE_RS00440
uniprot id: A0A856PVN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

89152:KGNDJEFE RS06710
gene id: 89152:KGNDJEFE_RS06710
uniprot id: A0A7T8ZQH7
names: Similarity
messages: Belongs to the RutC family.

89152:KGNDJEFE RS05635
gene id: 89152:KGNDJEFE_RS05635
uniprot id: A0A856PY53
names: Similarity
messages: Belongs to the peptidase M24B family.

89152:KGNDJEFE RS09375
gene id: 89152:KGNDJEFE_RS09375
uniprot id: A0A856Q0D1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89152:KGNDJEFE RS01420
gene id: 89152:KGNDJEFE_RS01420
uniprot id: A0A856PVT4
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

89152:KGNDJEFE RS10735
gene id: 89152:KGNDJEFE_RS10735
uniprot id: A0A856Q2E0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

89152:KGNDJEFE RS07325
gene id: 89152:KGNDJEFE_RS07325
uniprot id: A0A856PZ86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

89152:KGNDJEFE RS06650
gene id: 89152:KGNDJEFE_RS06650
uniprot id: A0A856PYV9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS08570
gene id: 89152:KGNDJEFE_RS08570
uniprot id: A0A856PZI0
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

89152:KGNDJEFE RS03670
gene id: 89152:KGNDJEFE_RS03670
uniprot id: A0A856PXQ5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

89152:KGNDJEFE RS09740
gene id: 89152:KGNDJEFE_RS09740
uniprot id: A0A856Q0K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

89152:KGNDJEFE RS10075
gene id: 89152:KGNDJEFE_RS10075
uniprot id: A0A856Q0J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

89152:KGNDJEFE RS07450
gene id: 89152:KGNDJEFE_RS07450
uniprot id: A0A856PZG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS00270
gene id: 89152:KGNDJEFE_RS00270
uniprot id: A0A856PVG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

89152:KGNDJEFE RS06625
gene id: 89152:KGNDJEFE_RS06625
uniprot id: A0A856PZA4
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS05815
gene id: 89152:KGNDJEFE_RS05815
uniprot id: A0A856PY98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

89152:KGNDJEFE RS02545
gene id: 89152:KGNDJEFE_RS02545
uniprot id: A0A856PWB9
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

89152:KGNDJEFE RS02970
gene id: 89152:KGNDJEFE_RS02970
uniprot id: A0A856PX57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

89152:KGNDJEFE RS11270
gene id: 89152:KGNDJEFE_RS11270
uniprot id: A0A856Q1U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

89152:KGNDJEFE RS03270
gene id: 89152:KGNDJEFE_RS03270
uniprot id: A0A856PYI9
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

89152:KGNDJEFE RS04815
gene id: 89152:KGNDJEFE_RS04815
uniprot id: A0A856PY79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS00860
gene id: 89152:KGNDJEFE_RS00860
uniprot id: A0A856PVK0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

89152:KGNDJEFE RS06485
gene id: 89152:KGNDJEFE_RS06485
uniprot id: A0A856PYD4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

89152:KGNDJEFE RS11110
gene id: 89152:KGNDJEFE_RS11110
uniprot id: A0A856Q2G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

89152:KGNDJEFE RS02055
gene id: 89152:KGNDJEFE_RS02055
uniprot id: A0A856PWK7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

89152:KGNDJEFE RS09380
gene id: 89152:KGNDJEFE_RS09380
uniprot id: A0A7T8ZR42
names: Similarity
messages: Belongs to the RutC family.

89152:KGNDJEFE RS02565
gene id: 89152:KGNDJEFE_RS02565
uniprot id: A0A856PX38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

89152:KGNDJEFE RS00910
gene id: 89152:KGNDJEFE_RS00910
uniprot id: A0A856PVL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

89152:KGNDJEFE RS02310
gene id: 89152:KGNDJEFE_RS02310
uniprot id: A0A856PWD5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

89152:KGNDJEFE RS01290
gene id: 89152:KGNDJEFE_RS01290
uniprot id: A0A856PW04
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

89152:KGNDJEFE RS10185
gene id: 89152:KGNDJEFE_RS10185
uniprot id: A0A856Q1J5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

89152:KGNDJEFE RS09470
gene id: 89152:KGNDJEFE_RS09470
uniprot id: A0A7T8ZQU6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

89152:KGNDJEFE RS09430
gene id: 89152:KGNDJEFE_RS09430
uniprot id: A0A7T8V4C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

89152:KGNDJEFE RS05550
gene id: 89152:KGNDJEFE_RS05550
uniprot id: A0A856PYN3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS10730
gene id: 89152:KGNDJEFE_RS10730
uniprot id: A0A856Q1S8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

89152:KGNDJEFE RS05895
gene id: 89152:KGNDJEFE_RS05895
uniprot id: A0A856PY99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

89152:KGNDJEFE RS03970
gene id: 89152:KGNDJEFE_RS03970
uniprot id: A0A856PXV9
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

89152:KGNDJEFE RS04750
gene id: 89152:KGNDJEFE_RS04750
uniprot id: A0A856PXN6
names: Similarity
messages: Belongs to the RNase H family.

89152:KGNDJEFE RS09920
gene id: 89152:KGNDJEFE_RS09920
uniprot id: A0A856Q0V9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

89152:KGNDJEFE RS07715
gene id: 89152:KGNDJEFE_RS07715
uniprot id: A0A856PZE0
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

89152:KGNDJEFE RS09260
gene id: 89152:KGNDJEFE_RS09260
uniprot id: A0A7T8V4B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS05290
gene id: 89152:KGNDJEFE_RS05290
uniprot id: A0A7T8V593
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

89152:KGNDJEFE RS00300
gene id: 89152:KGNDJEFE_RS00300
uniprot id: A0A7T8V355
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

89152:KGNDJEFE RS11610
gene id: 89152:KGNDJEFE_RS11610
uniprot id: A0A856Q1Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS02190
gene id: 89152:KGNDJEFE_RS02190
uniprot id: A0A856PW82
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS00800
gene id: 89152:KGNDJEFE_RS00800
uniprot id: A0A856PVQ7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS03405
gene id: 89152:KGNDJEFE_RS03405
uniprot id: A0A7T8V244
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

89152:KGNDJEFE RS07560
gene id: 89152:KGNDJEFE_RS07560
uniprot id: A0A856Q026
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

89152:KGNDJEFE RS03080
gene id: 89152:KGNDJEFE_RS03080
uniprot id: A0A856PWL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

89152:KGNDJEFE RS07550
gene id: 89152:KGNDJEFE_RS07550
uniprot id: A0A7T8V1Q9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

89152:KGNDJEFE RS11040
gene id: 89152:KGNDJEFE_RS11040
uniprot id: A0A7T8V3I7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

89152:KGNDJEFE RS02025
gene id: 89152:KGNDJEFE_RS02025
uniprot id: A0A856PW18
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

89152:KGNDJEFE RS01470
gene id: 89152:KGNDJEFE_RS01470
uniprot id: A0A856PVU3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

89152:KGNDJEFE RS06750
gene id: 89152:KGNDJEFE_RS06750
uniprot id: A0A856PZ16
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

89152:KGNDJEFE RS04990
gene id: 89152:KGNDJEFE_RS04990
uniprot id: A0A856PXU0
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

89152:KGNDJEFE RS05405
gene id: 89152:KGNDJEFE_RS05405
uniprot id: A0A856PY17
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

89152:KGNDJEFE RS02100
gene id: 89152:KGNDJEFE_RS02100
uniprot id: A0A856PXT4
names: Function
names: Similarity
messages: A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3'.
messages: Belongs to the DpnII type II restriction endonuclease family.

89152:KGNDJEFE RS08470
gene id: 89152:KGNDJEFE_RS08470
uniprot id: A0A7T8ZRT4
names: Similarity
messages: Belongs to the RNase H family.

89152:KGNDJEFE RS06730
gene id: 89152:KGNDJEFE_RS06730
uniprot id: A0A856PYI6
names: Similarity
messages: Belongs to the pirin family.

89152:KGNDJEFE RS04590
gene id: 89152:KGNDJEFE_RS04590
uniprot id: A0A7T8V255
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

89152:KGNDJEFE RS06825
gene id: 89152:KGNDJEFE_RS06825
uniprot id: A0A856PYW6
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS02015
gene id: 89152:KGNDJEFE_RS02015
uniprot id: A0A7T8V2W1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS01820
gene id: 89152:KGNDJEFE_RS01820
uniprot id: A0A7T8ZQG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

89152:KGNDJEFE RS10710
gene id: 89152:KGNDJEFE_RS10710
uniprot id: A0A856Q135
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

89152:KGNDJEFE RS05295
gene id: 89152:KGNDJEFE_RS05295
uniprot id: A0A856PZQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

89152:KGNDJEFE RS10205
gene id: 89152:KGNDJEFE_RS10205
uniprot id: A0A856Q0C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS05505
gene id: 89152:KGNDJEFE_RS05505
uniprot id: A0A856PY39
names: Similarity
messages: Belongs to the peptidase M24B family.

89152:KGNDJEFE RS03865
gene id: 89152:KGNDJEFE_RS03865
uniprot id: A0A856PXT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

89152:KGNDJEFE RS11550
gene id: 89152:KGNDJEFE_RS11550
uniprot id: A0A856Q1J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

89152:KGNDJEFE RS08375
gene id: 89152:KGNDJEFE_RS08375
uniprot id: A0A7T8ZQX4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

89152:KGNDJEFE RS10750
gene id: 89152:KGNDJEFE_RS10750
uniprot id: A0A856Q0N4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

89152:KGNDJEFE RS02040
gene id: 89152:KGNDJEFE_RS02040
uniprot id: A0A856PW91
names: Similarity
messages: Belongs to the alkaline phosphatase family.

89152:KGNDJEFE RS04475
gene id: 89152:KGNDJEFE_RS04475
uniprot id: A0A7T8ZPQ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

89152:KGNDJEFE RS01190
gene id: 89152:KGNDJEFE_RS01190
uniprot id: A0A7T8V2Y4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS10360
gene id: 89152:KGNDJEFE_RS10360
uniprot id: A0A856Q0W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS09285
gene id: 89152:KGNDJEFE_RS09285
uniprot id: A0A856Q0J6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

89152:KGNDJEFE RS04300
gene id: 89152:KGNDJEFE_RS04300
uniprot id: A0A856PXM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

89152:KGNDJEFE RS09820
gene id: 89152:KGNDJEFE_RS09820
uniprot id: A0A856Q0U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

89152:KGNDJEFE RS09115
gene id: 89152:KGNDJEFE_RS09115
uniprot id: A0A856Q072
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

89152:KGNDJEFE RS02220
gene id: 89152:KGNDJEFE_RS02220
uniprot id: A0A856PXW1
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS11465
gene id: 89152:KGNDJEFE_RS11465
uniprot id: A0A856Q1Z0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

89152:KGNDJEFE RS02665
gene id: 89152:KGNDJEFE_RS02665
uniprot id: A0A856PX65
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

89152:KGNDJEFE RS02435
gene id: 89152:KGNDJEFE_RS02435
uniprot id: A0A856PWA4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

89152:KGNDJEFE RS09935
gene id: 89152:KGNDJEFE_RS09935
uniprot id: A0A856Q262
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS00145
gene id: 89152:KGNDJEFE_RS00145
uniprot id: A0A7T8ZRA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

89152:KGNDJEFE RS06020
gene id: 89152:KGNDJEFE_RS06020
uniprot id: A0A7T8V188
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS07135
gene id: 89152:KGNDJEFE_RS07135
uniprot id: A0A856PZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

89152:KGNDJEFE RS11375
gene id: 89152:KGNDJEFE_RS11375
uniprot id: A0A856Q0Z2
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS01925
gene id: 89152:KGNDJEFE_RS01925
uniprot id: A0A856PW02
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

89152:KGNDJEFE RS09215
gene id: 89152:KGNDJEFE_RS09215
uniprot id: A0A856PZU8
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

89152:KGNDJEFE RS08950
gene id: 89152:KGNDJEFE_RS08950
uniprot id: A0A856Q0R7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

89152:KGNDJEFE RS03125
gene id: 89152:KGNDJEFE_RS03125
uniprot id: A0A856PWN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

89152:KGNDJEFE RS08140
gene id: 89152:KGNDJEFE_RS08140
uniprot id: A0A856PZP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

89152:KGNDJEFE RS01645
gene id: 89152:KGNDJEFE_RS01645
uniprot id: A0A856PWI2
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

89152:KGNDJEFE RS08425
gene id: 89152:KGNDJEFE_RS08425
uniprot id: A0A856PZU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS04445
gene id: 89152:KGNDJEFE_RS04445
uniprot id: A0A856PXP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS07545
gene id: 89152:KGNDJEFE_RS07545
uniprot id: A0A7T8ZPZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

89152:KGNDJEFE RS11050
gene id: 89152:KGNDJEFE_RS11050
uniprot id: A0A856Q2G0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

89152:KGNDJEFE RS02125
gene id: 89152:KGNDJEFE_RS02125
uniprot id: A0A856PW36
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

89152:KGNDJEFE RS03005
gene id: 89152:KGNDJEFE_RS03005
uniprot id: A0A856PWQ4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

89152:KGNDJEFE RS02985
gene id: 89152:KGNDJEFE_RS02985
uniprot id: A0A7T8V2G0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

89152:KGNDJEFE RS09525
gene id: 89152:KGNDJEFE_RS09525
uniprot id: A0A856Q0G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

89152:KGNDJEFE RS03220
gene id: 89152:KGNDJEFE_RS03220
uniprot id: A0A856PYH8
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

89152:KGNDJEFE RS10165
gene id: 89152:KGNDJEFE_RS10165
uniprot id: A0A856Q0W4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

89152:KGNDJEFE RS02150
gene id: 89152:KGNDJEFE_RS02150
uniprot id: A0A856PXU7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

89152:KGNDJEFE RS04710
gene id: 89152:KGNDJEFE_RS04710
uniprot id: A0A7T8ZPP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

89152:KGNDJEFE RS01700
gene id: 89152:KGNDJEFE_RS01700
uniprot id: A0A856PXJ0
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS09350
gene id: 89152:KGNDJEFE_RS09350
uniprot id: A0A856Q146
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS08005
gene id: 89152:KGNDJEFE_RS08005
uniprot id: A0A856PZT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS05905
gene id: 89152:KGNDJEFE_RS05905
uniprot id: A0A856Q027
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

89152:KGNDJEFE RS09605
gene id: 89152:KGNDJEFE_RS09605
uniprot id: A0A856Q224
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

89152:KGNDJEFE RS08440
gene id: 89152:KGNDJEFE_RS08440
uniprot id: A0A856Q020
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

89152:KGNDJEFE RS06560
gene id: 89152:KGNDJEFE_RS06560
uniprot id: A0A856PYN1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

89152:KGNDJEFE RS01740
gene id: 89152:KGNDJEFE_RS01740
uniprot id: A0A856PW35
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

89152:KGNDJEFE RS08750
gene id: 89152:KGNDJEFE_RS08750
uniprot id: A0A856Q0M5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

89152:KGNDJEFE RS07610
gene id: 89152:KGNDJEFE_RS07610
uniprot id: A0A856Q038
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

89152:KGNDJEFE RS10935
gene id: 89152:KGNDJEFE_RS10935
uniprot id: A0A856Q1B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS03280
gene id: 89152:KGNDJEFE_RS03280
uniprot id: A0A856PWR8
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

89152:KGNDJEFE RS02965
gene id: 89152:KGNDJEFE_RS02965
uniprot id: A0A856PYC5
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

89152:KGNDJEFE RS04875
gene id: 89152:KGNDJEFE_RS04875
uniprot id: A0A856PXI3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS03825
gene id: 89152:KGNDJEFE_RS03825
uniprot id: A0A856PYV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

89152:KGNDJEFE RS05085
gene id: 89152:KGNDJEFE_RS05085
uniprot id: A0A7T8ZRZ5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS04210
gene id: 89152:KGNDJEFE_RS04210
uniprot id: A0A856PXC6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

89152:KGNDJEFE RS07490
gene id: 89152:KGNDJEFE_RS07490
uniprot id: A0A856PZ92
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

89152:KGNDJEFE RS03260
gene id: 89152:KGNDJEFE_RS03260
uniprot id: A0A856PWU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

89152:KGNDJEFE RS07220
gene id: 89152:KGNDJEFE_RS07220
uniprot id: A0A856PZN0
names: Similarity
messages: Belongs to the glutamine synthetase family.

89152:KGNDJEFE RS11365
gene id: 89152:KGNDJEFE_RS11365
uniprot id: A0A7T8ZQH3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

89152:KGNDJEFE RS09970
gene id: 89152:KGNDJEFE_RS09970
uniprot id: A0A856Q0W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS03290
gene id: 89152:KGNDJEFE_RS03290
uniprot id: A0A7T8V2B3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

89152:KGNDJEFE RS06440
gene id: 89152:KGNDJEFE_RS06440
uniprot id: A0A7T8V1F5
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

89152:KGNDJEFE RS09560
gene id: 89152:KGNDJEFE_RS09560
uniprot id: A0A856Q130
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

89152:KGNDJEFE RS01195
gene id: 89152:KGNDJEFE_RS01195
uniprot id: A0A7T8V2X3
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

89152:KGNDJEFE RS04570
gene id: 89152:KGNDJEFE_RS04570
uniprot id: A0A856PY25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

89152:KGNDJEFE RS09425
gene id: 89152:KGNDJEFE_RS09425
uniprot id: A0A856Q0E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

89152:KGNDJEFE RS08180
gene id: 89152:KGNDJEFE_RS08180
uniprot id: A0A856PZS7
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

89152:KGNDJEFE RS08080
gene id: 89152:KGNDJEFE_RS08080
uniprot id: A0A856PZQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

89152:KGNDJEFE RS04410
gene id: 89152:KGNDJEFE_RS04410
uniprot id: A0A856PY58
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS05120
gene id: 89152:KGNDJEFE_RS05120
uniprot id: A0A856PXW6
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS01065
gene id: 89152:KGNDJEFE_RS01065
uniprot id: A0A856PVM8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

89152:KGNDJEFE RS02390
gene id: 89152:KGNDJEFE_RS02390
uniprot id: A0A856PWC8
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

89152:KGNDJEFE RS01845
gene id: 89152:KGNDJEFE_RS01845
uniprot id: A0A856PWM4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

89152:KGNDJEFE RS07290
gene id: 89152:KGNDJEFE_RS07290
uniprot id: A0A856PZ43
names: Similarity
messages: Belongs to the peptidase M16 family.

89152:KGNDJEFE RS08770
gene id: 89152:KGNDJEFE_RS08770
uniprot id: A0A856Q015
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

89152:KGNDJEFE RS02615
gene id: 89152:KGNDJEFE_RS02615
uniprot id: A0A856PX52
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

89152:KGNDJEFE RS06050
gene id: 89152:KGNDJEFE_RS06050
uniprot id: A0A856Q058
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

89152:KGNDJEFE RS03420
gene id: 89152:KGNDJEFE_RS03420
uniprot id: A0A856PYL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

89152:KGNDJEFE RS09395
gene id: 89152:KGNDJEFE_RS09395
uniprot id: A0A856Q084
names: Similarity
messages: Belongs to the asparaginase 1 family.

89152:KGNDJEFE RS08640
gene id: 89152:KGNDJEFE_RS08640
uniprot id: A0A856Q060
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

89152:KGNDJEFE RS10405
gene id: 89152:KGNDJEFE_RS10405
uniprot id: A0A856Q0G7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

89152:KGNDJEFE RS10120
gene id: 89152:KGNDJEFE_RS10120
uniprot id: A0A856Q101
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

89152:KGNDJEFE RS05715
gene id: 89152:KGNDJEFE_RS05715
uniprot id: A0A856PY87
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS08775
gene id: 89152:KGNDJEFE_RS08775
uniprot id: A0A856Q034
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

89152:KGNDJEFE RS02500
gene id: 89152:KGNDJEFE_RS02500
uniprot id: A0A856PWN2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS01360
gene id: 89152:KGNDJEFE_RS01360
uniprot id: A0A856PVS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

89152:KGNDJEFE RS04500
gene id: 89152:KGNDJEFE_RS04500
uniprot id: A0A856PXR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

89152:KGNDJEFE RS00020
gene id: 89152:KGNDJEFE_RS00020
uniprot id: A0A856PVC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

89152:KGNDJEFE RS07380
gene id: 89152:KGNDJEFE_RS07380
uniprot id: A0A856PYW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

89152:KGNDJEFE RS04920
gene id: 89152:KGNDJEFE_RS04920
uniprot id: A0A856PXI8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

89152:KGNDJEFE RS03340
gene id: 89152:KGNDJEFE_RS03340
uniprot id: A0A856PWV0
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS03790
gene id: 89152:KGNDJEFE_RS03790
uniprot id: A0A856PWY0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

89152:KGNDJEFE RS01095
gene id: 89152:KGNDJEFE_RS01095
uniprot id: A0A856PVW2
names: Similarity
messages: Belongs to the UPF0173 family.

89152:KGNDJEFE RS04190
gene id: 89152:KGNDJEFE_RS04190
uniprot id: A0A856PXC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

89152:KGNDJEFE RS08760
gene id: 89152:KGNDJEFE_RS08760
uniprot id: A0A856PZL5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

89152:KGNDJEFE RS09505
gene id: 89152:KGNDJEFE_RS09505
uniprot id: A0A856Q213
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

89152:KGNDJEFE RS01720
gene id: 89152:KGNDJEFE_RS01720
uniprot id: A0A7T8V309
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

89152:KGNDJEFE RS06405
gene id: 89152:KGNDJEFE_RS06405
uniprot id: A0A856PYR3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

89152:KGNDJEFE RS05615
gene id: 89152:KGNDJEFE_RS05615
uniprot id: A0A856PY66
names: Similarity
messages: Belongs to the UPF0751 family.

89152:KGNDJEFE RS08955
gene id: 89152:KGNDJEFE_RS08955
uniprot id: A0A856Q090
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

89152:KGNDJEFE RS04360
gene id: 89152:KGNDJEFE_RS04360
uniprot id: A0A856PY42
names: Function
names: Similarity
messages: Belongs to the peptidase S33 family.
messages: Releases the N-terminal proline from various substrates.

89152:KGNDJEFE RS08050
gene id: 89152:KGNDJEFE_RS08050
uniprot id: A0A856PZP4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89152:KGNDJEFE RS00090
gene id: 89152:KGNDJEFE_RS00090
uniprot id: A0A856PVI1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS00930
gene id: 89152:KGNDJEFE_RS00930
uniprot id: A0A856PVT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

89152:KGNDJEFE RS10940
gene id: 89152:KGNDJEFE_RS10940
uniprot id: A0A856Q1F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

89152:KGNDJEFE RS00110
gene id: 89152:KGNDJEFE_RS00110
uniprot id: A0A7T8V3C6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

89152:KGNDJEFE RS04335
gene id: 89152:KGNDJEFE_RS04335
uniprot id: A0A856PXF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

89152:KGNDJEFE RS10050
gene id: 89152:KGNDJEFE_RS10050
uniprot id: A0A7T8ZR00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

89152:KGNDJEFE RS09145
gene id: 89152:KGNDJEFE_RS09145
uniprot id: A0A856Q1U9
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS10520
gene id: 89152:KGNDJEFE_RS10520
uniprot id: A0A856Q137
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

89152:KGNDJEFE RS11015
gene id: 89152:KGNDJEFE_RS11015
uniprot id: A0A856Q1F7
names: Similarity
messages: Belongs to the GARS family.

89152:KGNDJEFE RS07350
gene id: 89152:KGNDJEFE_RS07350
uniprot id: A0A856PZE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

89152:KGNDJEFE RS00315
gene id: 89152:KGNDJEFE_RS00315
uniprot id: A0A7T8ZQM2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

89152:KGNDJEFE RS08040
gene id: 89152:KGNDJEFE_RS08040
uniprot id: A0A856PZM4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89152:KGNDJEFE RS10430
gene id: 89152:KGNDJEFE_RS10430
uniprot id: A0A856Q0R6
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS00125
gene id: 89152:KGNDJEFE_RS00125
uniprot id: A0A7T8V396
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

89152:KGNDJEFE RS03680
gene id: 89152:KGNDJEFE_RS03680
uniprot id: A0A856PXJ8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

89152:KGNDJEFE RS11340
gene id: 89152:KGNDJEFE_RS11340
uniprot id: A0A7T8ZRC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

89152:KGNDJEFE RS00805
gene id: 89152:KGNDJEFE_RS00805
uniprot id: A0A856PW63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

89152:KGNDJEFE RS02670
gene id: 89152:KGNDJEFE_RS02670
uniprot id: A0A856PY68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

89152:KGNDJEFE RS05055
gene id: 89152:KGNDJEFE_RS05055
uniprot id: A0A856PYD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

89152:KGNDJEFE RS01145
gene id: 89152:KGNDJEFE_RS01145
uniprot id: A0A856PVX1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS02930
gene id: 89152:KGNDJEFE_RS02930
uniprot id: A0A856PWJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS08265
gene id: 89152:KGNDJEFE_RS08265
uniprot id: A0A856Q0C0
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS00280
gene id: 89152:KGNDJEFE_RS00280
uniprot id: A0A7T8ZS02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

89152:KGNDJEFE RS10785
gene id: 89152:KGNDJEFE_RS10785
uniprot id: A0A856Q2E5
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

89152:KGNDJEFE RS00360
gene id: 89152:KGNDJEFE_RS00360
uniprot id: A0A856PVH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

89152:KGNDJEFE RS02020
gene id: 89152:KGNDJEFE_RS02020
uniprot id: A0A856PW53
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

89152:KGNDJEFE RS10725
gene id: 89152:KGNDJEFE_RS10725
uniprot id: A0A856Q0X3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

89152:KGNDJEFE RS00130
gene id: 89152:KGNDJEFE_RS00130
uniprot id: A0A7T8V362
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

89152:KGNDJEFE RS08660
gene id: 89152:KGNDJEFE_RS08660
uniprot id: A0A856Q0K3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

89152:KGNDJEFE RS08385
gene id: 89152:KGNDJEFE_RS08385
uniprot id: A0A856PZW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

89152:KGNDJEFE RS02815
gene id: 89152:KGNDJEFE_RS02815
uniprot id: A0A856PWM3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS06500
gene id: 89152:KGNDJEFE_RS06500
uniprot id: A0A856PYS9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

89152:KGNDJEFE RS06635
gene id: 89152:KGNDJEFE_RS06635
uniprot id: A0A856PYG3
names: Subcellular Location Annotation
messages: Periplasm

89152:KGNDJEFE RS00725
gene id: 89152:KGNDJEFE_RS00725
uniprot id: A0A856PVI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

89152:KGNDJEFE RS11390
gene id: 89152:KGNDJEFE_RS11390
uniprot id: A0A7T8V3F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

89152:KGNDJEFE RS10180
gene id: 89152:KGNDJEFE_RS10180
uniprot id: A0A856Q0M0
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

89152:KGNDJEFE RS07205
gene id: 89152:KGNDJEFE_RS07205
uniprot id: A0A7T8V1M0
names: Subcellular Location Annotation
messages: Cytoplasm

89152:KGNDJEFE RS03140
gene id: 89152:KGNDJEFE_RS03140
uniprot id: A0A856PWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

89152:KGNDJEFE RS02520
gene id: 89152:KGNDJEFE_RS02520
uniprot id: A0A7T8V2T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

89152:KGNDJEFE RS06840
gene id: 89152:KGNDJEFE_RS06840
uniprot id: A0A856PYU4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS04785
gene id: 89152:KGNDJEFE_RS04785
uniprot id: A0A7T8V4R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS01730
gene id: 89152:KGNDJEFE_RS01730
uniprot id: A0A7T8V2V6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

89152:KGNDJEFE RS02790
gene id: 89152:KGNDJEFE_RS02790
uniprot id: A0A856PWG7
names: Similarity
messages: Belongs to the HepT RNase toxin family.

89152:KGNDJEFE RS09385
gene id: 89152:KGNDJEFE_RS09385
uniprot id: A0A856Q0G0
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

89152:KGNDJEFE RS05585
gene id: 89152:KGNDJEFE_RS05585
uniprot id: A0A856PY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

89152:KGNDJEFE RS02960
gene id: 89152:KGNDJEFE_RS02960
uniprot id: A0A856PXB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

89152:KGNDJEFE RS02685
gene id: 89152:KGNDJEFE_RS02685
uniprot id: A0A7T8V2J3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

89152:KGNDJEFE RS08580
gene id: 89152:KGNDJEFE_RS08580
uniprot id: A0A856PZW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

89152:KGNDJEFE RS08245
gene id: 89152:KGNDJEFE_RS08245
uniprot id: A0A856PZY2
names: Similarity
messages: Belongs to the peptidase S8 family.

89152:KGNDJEFE RS05855
gene id: 89152:KGNDJEFE_RS05855
uniprot id: A0A856Q014
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS06190
gene id: 89152:KGNDJEFE_RS06190
uniprot id: A0A856PYQ4
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

89152:KGNDJEFE RS11265
gene id: 89152:KGNDJEFE_RS11265
uniprot id: A0A856Q2I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

89152:KGNDJEFE RS05735
gene id: 89152:KGNDJEFE_RS05735
uniprot id: A0A856PYF9
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

89152:KGNDJEFE RS11205
gene id: 89152:KGNDJEFE_RS11205
uniprot id: A0A7T8V1B7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

89152:KGNDJEFE RS04835
gene id: 89152:KGNDJEFE_RS04835
uniprot id: A0A856PXL4
names: Subcellular Location Annotation
messages: Membrane

89152:KGNDJEFE RS09650
gene id: 89152:KGNDJEFE_RS09650
uniprot id: A0A856Q0C7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

89152:KGNDJEFE RS08300
gene id: 89152:KGNDJEFE_RS08300
uniprot id: A0A856Q0I5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

89152:KGNDJEFE RS03040
gene id: 89152:KGNDJEFE_RS03040
uniprot id: A0A856PWK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

89152:KGNDJEFE RS02585
gene id: 89152:KGNDJEFE_RS02585
uniprot id: A0A856PWD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

89152:KGNDJEFE RS04025
gene id: 89152:KGNDJEFE_RS04025
uniprot id: A0A856PXR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

89152:KGNDJEFE RS03885
gene id: 89152:KGNDJEFE_RS03885
uniprot id: A0A856PWZ6
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

89152:KGNDJEFE RS00175
gene id: 89152:KGNDJEFE_RS00175
uniprot id: A0A7T8V341
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

89152:KGNDJEFE RS02715
gene id: 89152:KGNDJEFE_RS02715
uniprot id: A0A856PX75
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

89152:KGNDJEFE RS02910
gene id: 89152:KGNDJEFE_RS02910
uniprot id: A0A7T8V2B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

89152:KGNDJEFE RS07275
gene id: 89152:KGNDJEFE_RS07275
uniprot id: A0A856PZ67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm