882378:RBRH RS07705
gene id: 882378:RBRH_RS07705
uniprot id: E5ARX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

882378:RBRH RS13660
gene id: 882378:RBRH_RS13660
uniprot id: E5AUN4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

882378:RBRH RS10115
gene id: 882378:RBRH_RS10115
uniprot id: E5AKW2
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS12880
gene id: 882378:RBRH_RS12880
uniprot id: E5AU36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

882378:RBRH RS04415
gene id: 882378:RBRH_RS04415
uniprot id: E5APM4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

882378:RBRH RS07045
gene id: 882378:RBRH_RS07045
uniprot id: E5ARF3
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

882378:RBRH RS08420
gene id: 882378:RBRH_RS08420
uniprot id: E5ASD9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

882378:RBRH RS05985
gene id: 882378:RBRH_RS05985
uniprot id: E5AQM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

882378:RBRH RS15145
gene id: 882378:RBRH_RS15145
uniprot id: E5AVP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

882378:RBRH RS09990
gene id: 882378:RBRH_RS09990
uniprot id: E5AKS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

882378:RBRH RS05800
gene id: 882378:RBRH_RS05800
uniprot id: E5AQJ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

882378:RBRH RS11535
gene id: 882378:RBRH_RS11535
uniprot id: E5AML0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

882378:RBRH RS02355
gene id: 882378:RBRH_RS02355
uniprot id: E5AN15
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

882378:RBRH RS02640
gene id: 882378:RBRH_RS02640
uniprot id: E5ANH4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS06250
gene id: 882378:RBRH_RS06250
uniprot id: E5AQU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

882378:RBRH RS02545
gene id: 882378:RBRH_RS02545
uniprot id: E5AN55
names: Subcellular Location Annotation
messages: Cell outer membrane

882378:RBRH RS12350
gene id: 882378:RBRH_RS12350
uniprot id: E5ATN0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882378:RBRH RS00545
gene id: 882378:RBRH_RS00545
uniprot id: E5AKK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

882378:RBRH RS05835
gene id: 882378:RBRH_RS05835
uniprot id: E5AQJ7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

882378:RBRH RS09510
gene id: 882378:RBRH_RS09510
uniprot id: E5ATA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

882378:RBRH RS03265
gene id: 882378:RBRH_RS03265
uniprot id: E5ANW4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

882378:RBRH RS07695
gene id: 882378:RBRH_RS07695
uniprot id: E5ARX2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

882378:RBRH RS11565
gene id: 882378:RBRH_RS11565
uniprot id: E5AML9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

882378:RBRH RS02315
gene id: 882378:RBRH_RS02315
uniprot id: E5AN07
names: Similarity
messages: Belongs to the UPF0758 family.

882378:RBRH RS06975
gene id: 882378:RBRH_RS06975
uniprot id: E5ARC9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

882378:RBRH RS01340
gene id: 882378:RBRH_RS01340
uniprot id: E5ALH6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

882378:RBRH RS02700
gene id: 882378:RBRH_RS02700
uniprot id: E5ANI8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

882378:RBRH RS12025
gene id: 882378:RBRH_RS12025
uniprot id: E5ANA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

882378:RBRH RS01355
gene id: 882378:RBRH_RS01355
uniprot id: E5ALH9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

882378:RBRH RS11085
gene id: 882378:RBRH_RS11085
uniprot id: E5ALW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

882378:RBRH RS11705
gene id: 882378:RBRH_RS11705
uniprot id: E5AMQ2
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS09210
gene id: 882378:RBRH_RS09210
uniprot id: E5ASX3
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS11885
gene id: 882378:RBRH_RS11885
uniprot id: E5AN73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

882378:RBRH RS09315
gene id: 882378:RBRH_RS09315
uniprot id: E5AT56
names: Subcellular Location Annotation
messages: Cytoplasm

882378:RBRH RS07205
gene id: 882378:RBRH_RS07205
uniprot id: E5ARI7
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

882378:RBRH RS11835
gene id: 882378:RBRH_RS11835
uniprot id: E5AN61
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS10700
gene id: 882378:RBRH_RS10700
uniprot id: E5ALN2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

882378:RBRH RS13075
gene id: 882378:RBRH_RS13075
uniprot id: E5AU77
names: Similarity
messages: Belongs to the thioesterase family.

882378:RBRH RS09200
gene id: 882378:RBRH_RS09200
uniprot id: E5ASX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

882378:RBRH RS03330
gene id: 882378:RBRH_RS03330
uniprot id: E5ANX8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

882378:RBRH RS10650
gene id: 882378:RBRH_RS10650
uniprot id: E5ALM0
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

882378:RBRH RS08760
gene id: 882378:RBRH_RS08760
uniprot id: E5ASL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

882378:RBRH RS08560
gene id: 882378:RBRH_RS08560
uniprot id: E5ASH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

882378:RBRH RS03635
gene id: 882378:RBRH_RS03635
uniprot id: E5AP49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

882378:RBRH RS08470
gene id: 882378:RBRH_RS08470
uniprot id: E5ASE9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

882378:RBRH RS03695
gene id: 882378:RBRH_RS03695
uniprot id: E5AP61
names: Similarity
messages: Belongs to the CFA/CMAS family.

882378:RBRH RS01135
gene id: 882378:RBRH_RS01135
uniprot id: E5ALE0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS01700
gene id: 882378:RBRH_RS01700
uniprot id: E5AM53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS04385
gene id: 882378:RBRH_RS04385
uniprot id: E5APK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

882378:RBRH RS08790
gene id: 882378:RBRH_RS08790
uniprot id: E5ASM6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS07075
gene id: 882378:RBRH_RS07075
uniprot id: E5ARF9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Belongs to the peptidase S8 family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS08955
gene id: 882378:RBRH_RS08955
uniprot id: E5ASR8
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS09995
gene id: 882378:RBRH_RS09995
uniprot id: E5AKS9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

882378:RBRH RS02760
gene id: 882378:RBRH_RS02760
uniprot id: E5ANK2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

882378:RBRH RS10110
gene id: 882378:RBRH_RS10110
uniprot id: E5AKW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

882378:RBRH RS15045
gene id: 882378:RBRH_RS15045
uniprot id: E5AVL5
names: Similarity
messages: Belongs to the ParB family.

882378:RBRH RS11370
gene id: 882378:RBRH_RS11370
uniprot id: E5AMH3
names: Similarity
messages: Belongs to the peptidase S11 family.

882378:RBRH RS04475
gene id: 882378:RBRH_RS04475
uniprot id: E5APN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

882378:RBRH RS11995
gene id: 882378:RBRH_RS11995
uniprot id: E5ANA2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

882378:RBRH RS04715
gene id: 882378:RBRH_RS04715
uniprot id: E5APU0
names: Similarity
messages: Belongs to the MlaA family.

882378:RBRH RS01385
gene id: 882378:RBRH_RS01385
uniprot id: E5ALI5
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS08545
gene id: 882378:RBRH_RS08545
uniprot id: E5ASG9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

882378:RBRH RS05845
gene id: 882378:RBRH_RS05845
uniprot id: E5AQJ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

882378:RBRH RS03075
gene id: 882378:RBRH_RS03075
uniprot id: E5ANS2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

882378:RBRH RS04605
gene id: 882378:RBRH_RS04605
uniprot id: E5APR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Homododecamer. Tetramer of trimer.
messages: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA.

882378:RBRH RS09015
gene id: 882378:RBRH_RS09015
uniprot id: E5AST4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882378:RBRH RS02205
gene id: 882378:RBRH_RS02205
uniprot id: E5AMY2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

882378:RBRH RS00580
gene id: 882378:RBRH_RS00580
uniprot id: E5AKL0
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

882378:RBRH RS03080
gene id: 882378:RBRH_RS03080
uniprot id: E5ANS4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

882378:RBRH RS11845
gene id: 882378:RBRH_RS11845
uniprot id: E5AN64
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882378:RBRH RS09805
gene id: 882378:RBRH_RS09805
uniprot id: E5ATG8
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

882378:RBRH RS14875
gene id: 882378:RBRH_RS14875
uniprot id: E5AVH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

882378:RBRH RS02340
gene id: 882378:RBRH_RS02340
uniprot id: E5AN12
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS08685
gene id: 882378:RBRH_RS08685
uniprot id: E5ASK3
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

882378:RBRH RS02230
gene id: 882378:RBRH_RS02230
uniprot id: E5AMY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

882378:RBRH RS06465
gene id: 882378:RBRH_RS06465
uniprot id: E5AQZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

882378:RBRH RS12300
gene id: 882378:RBRH_RS12300
uniprot id: E5ATL5
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

882378:RBRH RS03775
gene id: 882378:RBRH_RS03775
uniprot id: E5AP84
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

882378:RBRH RS09870
gene id: 882378:RBRH_RS09870
uniprot id: E5ATI5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

882378:RBRH RS03790
gene id: 882378:RBRH_RS03790
uniprot id: E5AP88
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

882378:RBRH RS06055
gene id: 882378:RBRH_RS06055
uniprot id: E5AQP3
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS07155
gene id: 882378:RBRH_RS07155
uniprot id: E5ARH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

882378:RBRH RS05715
gene id: 882378:RBRH_RS05715
uniprot id: E5AQG8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS06340
gene id: 882378:RBRH_RS06340
uniprot id: E5AQX0
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

882378:RBRH RS05315
gene id: 882378:RBRH_RS05315
uniprot id: E5AQ71
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

882378:RBRH RS06090
gene id: 882378:RBRH_RS06090
uniprot id: E5AQQ0
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

882378:RBRH RS05960
gene id: 882378:RBRH_RS05960
uniprot id: E5AQM4
names: Similarity
messages: Belongs to the asparaginase 1 family.

882378:RBRH RS04705
gene id: 882378:RBRH_RS04705
uniprot id: E5APT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

882378:RBRH RS07055
gene id: 882378:RBRH_RS07055
uniprot id: E5ARF5
names: Similarity
messages: Belongs to the BolA/IbaG family.

882378:RBRH RS04825
gene id: 882378:RBRH_RS04825
uniprot id: E5APW3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

882378:RBRH RS04430
gene id: 882378:RBRH_RS04430
uniprot id: E5APM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

882378:RBRH RS02530
gene id: 882378:RBRH_RS02530
uniprot id: E5AN52
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

882378:RBRH RS13560
gene id: 882378:RBRH_RS13560
uniprot id: E5AUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

882378:RBRH RS02835
gene id: 882378:RBRH_RS02835
uniprot id: E5ANL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

882378:RBRH RS14920
gene id: 882378:RBRH_RS14920
uniprot id: E5AVI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

882378:RBRH RS08190
gene id: 882378:RBRH_RS08190
uniprot id: E5AS88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

882378:RBRH RS02465
gene id: 882378:RBRH_RS02465
uniprot id: E5AN39
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882378:RBRH RS09045
gene id: 882378:RBRH_RS09045
uniprot id: E5ASU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

882378:RBRH RS13105
gene id: 882378:RBRH_RS13105
uniprot id: E5AU87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

882378:RBRH RS08585
gene id: 882378:RBRH_RS08585
uniprot id: E5ASH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

882378:RBRH RS04740
gene id: 882378:RBRH_RS04740
uniprot id: E5APU5
names: Similarity
messages: Belongs to the BolA/IbaG family.

882378:RBRH RS10800
gene id: 882378:RBRH_RS10800
uniprot id: E5ALQ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882378:RBRH RS03315
gene id: 882378:RBRH_RS03315
uniprot id: E5ANX5
names: Similarity
messages: Belongs to the fabD family.

882378:RBRH RS12660
gene id: 882378:RBRH_RS12660
uniprot id: E5ATX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

882378:RBRH RS10995
gene id: 882378:RBRH_RS10995
uniprot id: E5ALU7
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

882378:RBRH RS11605
gene id: 882378:RBRH_RS11605
uniprot id: E5AMN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882378:RBRH RS13575
gene id: 882378:RBRH_RS13575
uniprot id: E5AUL7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

882378:RBRH RS07905
gene id: 882378:RBRH_RS07905
uniprot id: E5AS22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

882378:RBRH RS13680
gene id: 882378:RBRH_RS13680
uniprot id: E5AUN9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

882378:RBRH RS08340
gene id: 882378:RBRH_RS08340
uniprot id: E5ASB9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

882378:RBRH RS14190
gene id: 882378:RBRH_RS14190
uniprot id: E5AV07
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS01495
gene id: 882378:RBRH_RS01495
uniprot id: E5AM05
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

882378:RBRH RS10765
gene id: 882378:RBRH_RS10765
uniprot id: E5ALP5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

882378:RBRH RS05990
gene id: 882378:RBRH_RS05990
uniprot id: E5AQN0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

882378:RBRH RS09850
gene id: 882378:RBRH_RS09850
uniprot id: E5ATI1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

882378:RBRH RS08290
gene id: 882378:RBRH_RS08290
uniprot id: E5ASA9
names: Similarity
messages: Belongs to the HesB/IscA family.

882378:RBRH RS10840
gene id: 882378:RBRH_RS10840
uniprot id: E5ALR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS05470
gene id: 882378:RBRH_RS05470
uniprot id: E5AQB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

882378:RBRH RS08565
gene id: 882378:RBRH_RS08565
uniprot id: E5ASH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

882378:RBRH RS04785
gene id: 882378:RBRH_RS04785
uniprot id: E5APV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

882378:RBRH RS05720
gene id: 882378:RBRH_RS05720
uniprot id: E5AQH0
names: Similarity
messages: Belongs to the thioredoxin family.

882378:RBRH RS02975
gene id: 882378:RBRH_RS02975
uniprot id: E5ANQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

882378:RBRH RS13180
gene id: 882378:RBRH_RS13180
uniprot id: E5AUA8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

882378:RBRH RS02985
gene id: 882378:RBRH_RS02985
uniprot id: E5ANQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

882378:RBRH RS08815
gene id: 882378:RBRH_RS08815
uniprot id: E5ASN2
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

882378:RBRH RS03145
gene id: 882378:RBRH_RS03145
uniprot id: E5ANT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

882378:RBRH RS15010
gene id: 882378:RBRH_RS15010
uniprot id: E5AVK6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882378:RBRH RS07700
gene id: 882378:RBRH_RS07700
uniprot id: E5ARX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

882378:RBRH RS03565
gene id: 882378:RBRH_RS03565
uniprot id: E5AP33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

882378:RBRH RS06615
gene id: 882378:RBRH_RS06615
uniprot id: E5AR29
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882378:RBRH RS04935
gene id: 882378:RBRH_RS04935
uniprot id: E5APZ0
names: Subcellular Location Annotation
messages: Cytoplasm

882378:RBRH RS02990
gene id: 882378:RBRH_RS02990
uniprot id: E5ANQ5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

882378:RBRH RS12015
gene id: 882378:RBRH_RS12015
uniprot id: E5ANA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

882378:RBRH RS10940
gene id: 882378:RBRH_RS10940
uniprot id: E5ALT5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

882378:RBRH RS12000
gene id: 882378:RBRH_RS12000
uniprot id: E5ANA3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

882378:RBRH RS01930
gene id: 882378:RBRH_RS01930
uniprot id: E5AMA2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

882378:RBRH RS05905
gene id: 882378:RBRH_RS05905
uniprot id: E5AQL1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

882378:RBRH RS04340
gene id: 882378:RBRH_RS04340
uniprot id: E5APK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

882378:RBRH RS07135
gene id: 882378:RBRH_RS07135
uniprot id: E5ARH3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

882378:RBRH RS11945
gene id: 882378:RBRH_RS11945
uniprot id: E5AN89
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS04755
gene id: 882378:RBRH_RS04755
uniprot id: E5APU8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

882378:RBRH RS01925
gene id: 882378:RBRH_RS01925
uniprot id: E5AMA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

882378:RBRH RS05005
gene id: 882378:RBRH_RS05005
uniprot id: E5AQ05
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS08350
gene id: 882378:RBRH_RS08350
uniprot id: E5ASC1
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

882378:RBRH RS09855
gene id: 882378:RBRH_RS09855
uniprot id: E5ATI2
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS09150
gene id: 882378:RBRH_RS09150
uniprot id: E5ASW2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

882378:RBRH RS05445
gene id: 882378:RBRH_RS05445
uniprot id: E5AQA1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

882378:RBRH RS02935
gene id: 882378:RBRH_RS02935
uniprot id: E5ANP4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

882378:RBRH RS01440
gene id: 882378:RBRH_RS01440
uniprot id: E5ALJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

882378:RBRH RS08120
gene id: 882378:RBRH_RS08120
uniprot id: E5AS74
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882378:RBRH RS01125
gene id: 882378:RBRH_RS01125
uniprot id: E5ALD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

882378:RBRH RS06545
gene id: 882378:RBRH_RS06545
uniprot id: E5AR13
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

882378:RBRH RS07270
gene id: 882378:RBRH_RS07270
uniprot id: E5ARK4
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

882378:RBRH RS09945
gene id: 882378:RBRH_RS09945
uniprot id: E5AKR9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

882378:RBRH RS07875
gene id: 882378:RBRH_RS07875
uniprot id: E5AS16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

882378:RBRH RS04840
gene id: 882378:RBRH_RS04840
uniprot id: E5APW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

882378:RBRH RS08705
gene id: 882378:RBRH_RS08705
uniprot id: E5ASK7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882378:RBRH RS06920
gene id: 882378:RBRH_RS06920
uniprot id: E5ARA9
names: Similarity
messages: Belongs to the UPF0229 family.

882378:RBRH RS04380
gene id: 882378:RBRH_RS04380
uniprot id: E5APL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

882378:RBRH RS10005
gene id: 882378:RBRH_RS10005
uniprot id: E5AKT2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

882378:RBRH RS10790
gene id: 882378:RBRH_RS10790
uniprot id: E5ALQ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

882378:RBRH RS04530
gene id: 882378:RBRH_RS04530
uniprot id: E5APQ1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

882378:RBRH RS00385
gene id: 882378:RBRH_RS00385
uniprot id: E5AKF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

882378:RBRH RS02395
gene id: 882378:RBRH_RS02395
uniprot id: E5AN25
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882378:RBRH RS01290
gene id: 882378:RBRH_RS01290
uniprot id: E5ALG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS12970
gene id: 882378:RBRH_RS12970
uniprot id: E5AU55
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

882378:RBRH RS02695
gene id: 882378:RBRH_RS02695
uniprot id: E5ANI7
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

882378:RBRH RS03370
gene id: 882378:RBRH_RS03370
uniprot id: E5ANY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

882378:RBRH RS13255
gene id: 882378:RBRH_RS13255
uniprot id: E5AUC7
names: Similarity
messages: Belongs to the YoeB family.

882378:RBRH RS14410
gene id: 882378:RBRH_RS14410
uniprot id: E5AV65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

882378:RBRH RS05560
gene id: 882378:RBRH_RS05560
uniprot id: E5AQD1
names: Similarity
messages: Belongs to the peptidase C40 family.

882378:RBRH RS01280
gene id: 882378:RBRH_RS01280
uniprot id: E5ALG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

882378:RBRH RS00340
gene id: 882378:RBRH_RS00340
uniprot id: E5AKE8
names: Similarity
messages: Belongs to the GSP N family.

882378:RBRH RS09535
gene id: 882378:RBRH_RS09535
uniprot id: E5ATA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

882378:RBRH RS09935
gene id: 882378:RBRH_RS09935
uniprot id: E5AKR7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

882378:RBRH RS10405
gene id: 882378:RBRH_RS10405
uniprot id: E5AL24
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS11290
gene id: 882378:RBRH_RS11290
uniprot id: E5AMF2
names: Subcellular Location Annotation
messages: Cytoplasm

882378:RBRH RS15190
gene id: 882378:RBRH_RS15190
uniprot id: E5AVQ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882378:RBRH RS03810
gene id: 882378:RBRH_RS03810
uniprot id: E5AP93
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

882378:RBRH RS15225
gene id: 882378:RBRH_RS15225
uniprot id: E5AVR1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

882378:RBRH RS02785
gene id: 882378:RBRH_RS02785
uniprot id: E5ANK8
names: Subcellular Location Annotation
messages: Cytoplasm

882378:RBRH RS03780
gene id: 882378:RBRH_RS03780
uniprot id: E5AP85
names: Similarity
messages: Belongs to the UDPGP type 2 family.

882378:RBRH RS01720
gene id: 882378:RBRH_RS01720
uniprot id: E5AM58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

882378:RBRH RS05025
gene id: 882378:RBRH_RS05025
uniprot id: E5AQ09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

882378:RBRH RS04820
gene id: 882378:RBRH_RS04820
uniprot id: E5APW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

882378:RBRH RS08825
gene id: 882378:RBRH_RS08825
uniprot id: E5ASN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

882378:RBRH RS09050
gene id: 882378:RBRH_RS09050
uniprot id: E5ASU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882378:RBRH RS14365
gene id: 882378:RBRH_RS14365
uniprot id: E5AV54
names: Similarity
messages: Belongs to the band 7/mec-2 family.

882378:RBRH RS05980
gene id: 882378:RBRH_RS05980
uniprot id: E5AQM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

882378:RBRH RS06005
gene id: 882378:RBRH_RS06005
uniprot id: E5AQN3
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS09820
gene id: 882378:RBRH_RS09820
uniprot id: E5ATH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

882378:RBRH RS12740
gene id: 882378:RBRH_RS12740
uniprot id: E5ATZ9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

882378:RBRH RS12095
gene id: 882378:RBRH_RS12095
uniprot id: E5ANC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

882378:RBRH RS03250
gene id: 882378:RBRH_RS03250
uniprot id: E5ANW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

882378:RBRH RS05545
gene id: 882378:RBRH_RS05545
uniprot id: E5AQC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882378:RBRH RS13705
gene id: 882378:RBRH_RS13705
uniprot id: E5AUP3
names: Cofactor
messages: Can also use Mn(2+) ion.

882378:RBRH RS12745
gene id: 882378:RBRH_RS12745
uniprot id: E5AU00
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS06380
gene id: 882378:RBRH_RS06380
uniprot id: E5AQX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

882378:RBRH RS05895
gene id: 882378:RBRH_RS05895
uniprot id: E5AQK9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

882378:RBRH RS11905
gene id: 882378:RBRH_RS11905
uniprot id: E5AN78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

882378:RBRH RS04410
gene id: 882378:RBRH_RS04410
uniprot id: E5APM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

882378:RBRH RS05035
gene id: 882378:RBRH_RS05035
uniprot id: E5AQ11
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

882378:RBRH RS04435
gene id: 882378:RBRH_RS04435
uniprot id: E5APM8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

882378:RBRH RS06520
gene id: 882378:RBRH_RS06520
uniprot id: E5AR07
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

882378:RBRH RS10015
gene id: 882378:RBRH_RS10015
uniprot id: E5AKT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

882378:RBRH RS09940
gene id: 882378:RBRH_RS09940
uniprot id: E5AKR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

882378:RBRH RS09285
gene id: 882378:RBRH_RS09285
uniprot id: E5AT48
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

882378:RBRH RS06175
gene id: 882378:RBRH_RS06175
uniprot id: E5AQS6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882378:RBRH RS08830
gene id: 882378:RBRH_RS08830
uniprot id: E5ASN6
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

882378:RBRH RS08295
gene id: 882378:RBRH_RS08295
uniprot id: E5ASB0
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

882378:RBRH RS05535
gene id: 882378:RBRH_RS05535
uniprot id: E5AQC5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

882378:RBRH RS05205
gene id: 882378:RBRH_RS05205
uniprot id: E5AQ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

882378:RBRH RS04770
gene id: 882378:RBRH_RS04770
uniprot id: E5APV2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

882378:RBRH RS05010
gene id: 882378:RBRH_RS05010
uniprot id: E5AQ06
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

882378:RBRH RS02885
gene id: 882378:RBRH_RS02885
uniprot id: E5ANM8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

882378:RBRH RS01795
gene id: 882378:RBRH_RS01795
uniprot id: E5AM74
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

882378:RBRH RS07235
gene id: 882378:RBRH_RS07235
uniprot id: E5ARJ5
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

882378:RBRH RS04180
gene id: 882378:RBRH_RS04180
uniprot id: E5APH6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

882378:RBRH RS07200
gene id: 882378:RBRH_RS07200
uniprot id: E5ARI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS02445
gene id: 882378:RBRH_RS02445
uniprot id: E5AN34
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

882378:RBRH RS10190
gene id: 882378:RBRH_RS10190
uniprot id: E5AKX8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

882378:RBRH RS08260
gene id: 882378:RBRH_RS08260
uniprot id: E5ASA3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

882378:RBRH RS01265
gene id: 882378:RBRH_RS01265
uniprot id: E5ALF9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS10125
gene id: 882378:RBRH_RS10125
uniprot id: E5AKW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

882378:RBRH RS04780
gene id: 882378:RBRH_RS04780
uniprot id: E5APV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

882378:RBRH RS02450
gene id: 882378:RBRH_RS02450
uniprot id: E5AN35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

882378:RBRH RS04320
gene id: 882378:RBRH_RS04320
uniprot id: E5APK2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

882378:RBRH RS04545
gene id: 882378:RBRH_RS04545
uniprot id: E5APQ5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

882378:RBRH RS15165
gene id: 882378:RBRH_RS15165
uniprot id: E5AVP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

882378:RBRH RS05225
gene id: 882378:RBRH_RS05225
uniprot id: E5AQ49
names: Similarity
messages: Belongs to the WrbA family.

882378:RBRH RS08965
gene id: 882378:RBRH_RS08965
uniprot id: E5ASS1
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

882378:RBRH RS02440
gene id: 882378:RBRH_RS02440
uniprot id: E5AN33
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS01500
gene id: 882378:RBRH_RS01500
uniprot id: E5AM06
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

882378:RBRH RS06450
gene id: 882378:RBRH_RS06450
uniprot id: E5AQZ1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS00540
gene id: 882378:RBRH_RS00540
uniprot id: E5AKK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

882378:RBRH RS01995
gene id: 882378:RBRH_RS01995
uniprot id: E5AMC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

882378:RBRH RS10665
gene id: 882378:RBRH_RS10665
uniprot id: E5ALM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

882378:RBRH RS02280
gene id: 882378:RBRH_RS02280
uniprot id: E5AMZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

882378:RBRH RS00240
gene id: 882378:RBRH_RS00240
uniprot id: E5AKC5
names: Similarity
messages: Belongs to the FGGY kinase family.

882378:RBRH RS15965
gene id: 882378:RBRH_RS15965
uniprot id: E5AWA2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

882378:RBRH RS09055
gene id: 882378:RBRH_RS09055
uniprot id: E5ASU2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

882378:RBRH RS02270
gene id: 882378:RBRH_RS02270
uniprot id: E5AMZ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS11215
gene id: 882378:RBRH_RS11215
uniprot id: E5AMD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

882378:RBRH RS04035
gene id: 882378:RBRH_RS04035
uniprot id: E5APE2
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

882378:RBRH RS10955
gene id: 882378:RBRH_RS10955
uniprot id: E5ALT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

882378:RBRH RS10590
gene id: 882378:RBRH_RS10590
uniprot id: E5ALK7
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

882378:RBRH RS03390
gene id: 882378:RBRH_RS03390
uniprot id: E5ANZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

882378:RBRH RS04965
gene id: 882378:RBRH_RS04965
uniprot id: E5APZ8
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

882378:RBRH RS10430
gene id: 882378:RBRH_RS10430
uniprot id: E5AL31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

882378:RBRH RS04425
gene id: 882378:RBRH_RS04425
uniprot id: E5APM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

882378:RBRH RS09980
gene id: 882378:RBRH_RS09980
uniprot id: E5AKS5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

882378:RBRH RS01690
gene id: 882378:RBRH_RS01690
uniprot id: E5AM52
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

882378:RBRH RS03385
gene id: 882378:RBRH_RS03385
uniprot id: E5ANZ0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

882378:RBRH RS05280
gene id: 882378:RBRH_RS05280
uniprot id: E5AQ64
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

882378:RBRH RS05525
gene id: 882378:RBRH_RS05525
uniprot id: E5AQC3
names: Similarity
messages: Belongs to the pirin family.

882378:RBRH RS03785
gene id: 882378:RBRH_RS03785
uniprot id: E5AP86
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

882378:RBRH RS01325
gene id: 882378:RBRH_RS01325
uniprot id: E5ALH3
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

882378:RBRH RS13010
gene id: 882378:RBRH_RS13010
uniprot id: E5AU64
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

882378:RBRH RS10435
gene id: 882378:RBRH_RS10435
uniprot id: E5AL32
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

882378:RBRH RS11735
gene id: 882378:RBRH_RS11735
uniprot id: E5AMR0
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

882378:RBRH RS03320
gene id: 882378:RBRH_RS03320
uniprot id: E5ANX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

882378:RBRH RS01515
gene id: 882378:RBRH_RS01515
uniprot id: E5AM10
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

882378:RBRH RS08200
gene id: 882378:RBRH_RS08200
uniprot id: E5AS91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

882378:RBRH RS08205
gene id: 882378:RBRH_RS08205
uniprot id: E5AS92
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS03305
gene id: 882378:RBRH_RS03305
uniprot id: E5ANX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

882378:RBRH RS02410
gene id: 882378:RBRH_RS02410
uniprot id: E5AN28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

882378:RBRH RS01415
gene id: 882378:RBRH_RS01415
uniprot id: E5ALJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

882378:RBRH RS10065
gene id: 882378:RBRH_RS10065
uniprot id: E5AKU9
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS04390
gene id: 882378:RBRH_RS04390
uniprot id: E5APL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

882378:RBRH RS09520
gene id: 882378:RBRH_RS09520
uniprot id: E5ATA4
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS00490
gene id: 882378:RBRH_RS00490
uniprot id: E5AKJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

882378:RBRH RS06385
gene id: 882378:RBRH_RS06385
uniprot id: E5AQX9
names: Similarity
messages: Belongs to the ArsC family.

882378:RBRH RS04455
gene id: 882378:RBRH_RS04455
uniprot id: E5APN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

882378:RBRH RS06445
gene id: 882378:RBRH_RS06445
uniprot id: E5AQZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

882378:RBRH RS08930
gene id: 882378:RBRH_RS08930
uniprot id: E5ASR0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882378:RBRH RS12040
gene id: 882378:RBRH_RS12040
uniprot id: E5ANB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

882378:RBRH RS03415
gene id: 882378:RBRH_RS03415
uniprot id: E5ANZ6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

882378:RBRH RS14555
gene id: 882378:RBRH_RS14555
uniprot id: E5AV95
names: Similarity
messages: Belongs to the ABC transporter superfamily.

882378:RBRH RS06405
gene id: 882378:RBRH_RS06405
uniprot id: E5AQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

882378:RBRH RS01965
gene id: 882378:RBRH_RS01965
uniprot id: E5AMA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

882378:RBRH RS15070
gene id: 882378:RBRH_RS15070
uniprot id: E5AVM0
names: Similarity
messages: Belongs to the Fur family.

882378:RBRH RS11315
gene id: 882378:RBRH_RS11315
uniprot id: E5AMF7
names: Similarity
messages: Belongs to the P(II) protein family.

882378:RBRH RS01410
gene id: 882378:RBRH_RS01410
uniprot id: E5ALJ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

882378:RBRH RS04515
gene id: 882378:RBRH_RS04515
uniprot id: E5APP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

882378:RBRH RS01725
gene id: 882378:RBRH_RS01725
uniprot id: E5AM59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

882378:RBRH RS03045
gene id: 882378:RBRH_RS03045
uniprot id: E5ANR6
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

882378:RBRH RS00975
gene id: 882378:RBRH_RS00975
uniprot id: E5ALA2
names: Subcellular Location Annotation
messages: Mitochondrion

882378:RBRH RS01260
gene id: 882378:RBRH_RS01260
uniprot id: E5ALG2
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

882378:RBRH RS04480
gene id: 882378:RBRH_RS04480
uniprot id: E5APN9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

882378:RBRH RS06560
gene id: 882378:RBRH_RS06560
uniprot id: E5AR17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

882378:RBRH RS14085
gene id: 882378:RBRH_RS14085
uniprot id: E5AUY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

882378:RBRH RS08860
gene id: 882378:RBRH_RS08860
uniprot id: E5ASP4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

882378:RBRH RS13810
gene id: 882378:RBRH_RS13810
uniprot id: E5AUR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

882378:RBRH RS02165
gene id: 882378:RBRH_RS02165
uniprot id: E5AMW9
names: Similarity
messages: Belongs to the UPF0434 family.

882378:RBRH RS02470
gene id: 882378:RBRH_RS02470
uniprot id: E5AN40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

882378:RBRH RS06590
gene id: 882378:RBRH_RS06590
uniprot id: E5AR23
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

882378:RBRH RS03555
gene id: 882378:RBRH_RS03555
uniprot id: E5AP31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

882378:RBRH RS02585
gene id: 882378:RBRH_RS02585
uniprot id: E5ANG2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS10965
gene id: 882378:RBRH_RS10965
uniprot id: E5ALU0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

882378:RBRH RS03420
gene id: 882378:RBRH_RS03420
uniprot id: E5ANZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

882378:RBRH RS04440
gene id: 882378:RBRH_RS04440
uniprot id: E5APM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

882378:RBRH RS09240
gene id: 882378:RBRH_RS09240
uniprot id: E5ASY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

882378:RBRH RS06580
gene id: 882378:RBRH_RS06580
uniprot id: E5AR21
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

882378:RBRH RS09655
gene id: 882378:RBRH_RS09655
uniprot id: E5ATD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

882378:RBRH RS02325
gene id: 882378:RBRH_RS02325
uniprot id: E5AN09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

882378:RBRH RS10455
gene id: 882378:RBRH_RS10455
uniprot id: E5AL36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

882378:RBRH RS05105
gene id: 882378:RBRH_RS05105
uniprot id: E5AQ26
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

882378:RBRH RS00155
gene id: 882378:RBRH_RS00155
uniprot id: E5AT21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

882378:RBRH RS12395
gene id: 882378:RBRH_RS12395
uniprot id: E5ATP9
names: Similarity
messages: Belongs to the citrate synthase family.

882378:RBRH RS04900
gene id: 882378:RBRH_RS04900
uniprot id: E5APY2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882378:RBRH RS08020
gene id: 882378:RBRH_RS08020
uniprot id: E5AS51
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

882378:RBRH RS04655
gene id: 882378:RBRH_RS04655
uniprot id: E5APS8
names: Similarity
messages: Belongs to the glutamate synthase family.

882378:RBRH RS00720
gene id: 882378:RBRH_RS00720
uniprot id: E5AKP1
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

882378:RBRH RS01855
gene id: 882378:RBRH_RS01855
uniprot id: E5AM87
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

882378:RBRH RS14940
gene id: 882378:RBRH_RS14940
uniprot id: E5AVJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

882378:RBRH RS09835
gene id: 882378:RBRH_RS09835
uniprot id: E5ATH8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

882378:RBRH RS01000
gene id: 882378:RBRH_RS01000
uniprot id: E5ALA7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

882378:RBRH RS14885
gene id: 882378:RBRH_RS14885
uniprot id: E5AVH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

882378:RBRH RS01885
gene id: 882378:RBRH_RS01885
uniprot id: E5AM93
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

882378:RBRH RS07975
gene id: 882378:RBRH_RS07975
uniprot id: E5AS41
names: Similarity
messages: Belongs to the aspartokinase family.

882378:RBRH RS04585
gene id: 882378:RBRH_RS04585
uniprot id: E5APR3
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

882378:RBRH RS16310
gene id: 882378:RBRH_RS16310
uniprot id: E5ATI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS17160
gene id: 882378:RBRH_RS17160
uniprot id: E5AR97
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

882378:RBRH RS03030
gene id: 882378:RBRH_RS03030
uniprot id: E5ANR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882378:RBRH RS00585
gene id: 882378:RBRH_RS00585
uniprot id: E5AKK9
names: Similarity
messages: Belongs to the leucine-binding protein family.

882378:RBRH RS07800
gene id: 882378:RBRH_RS07800
uniprot id: E5ARZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

882378:RBRH RS06955
gene id: 882378:RBRH_RS06955
uniprot id: E5ARC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

882378:RBRH RS07600
gene id: 882378:RBRH_RS07600
uniprot id: E5ARU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

882378:RBRH RS08580
gene id: 882378:RBRH_RS08580
uniprot id: E5ASH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

882378:RBRH RS11360
gene id: 882378:RBRH_RS11360
uniprot id: E5AMG7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882378:RBRH RS05810
gene id: 882378:RBRH_RS05810
uniprot id: E5AQJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

882378:RBRH RS08575
gene id: 882378:RBRH_RS08575
uniprot id: E5ASH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

882378:RBRH RS01255
gene id: 882378:RBRH_RS01255
uniprot id: E5ALG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

882378:RBRH RS04350
gene id: 882378:RBRH_RS04350
uniprot id: E5APL1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

882378:RBRH RS01305
gene id: 882378:RBRH_RS01305
uniprot id: E5ALG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

882378:RBRH RS04315
gene id: 882378:RBRH_RS04315
uniprot id: E5APK1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS06640
gene id: 882378:RBRH_RS06640
uniprot id: E5AR37
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882378:RBRH RS05050
gene id: 882378:RBRH_RS05050
uniprot id: E5AQ14
names: Similarity
messages: Belongs to the TrpC family.

882378:RBRH RS14915
gene id: 882378:RBRH_RS14915
uniprot id: E5AVI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane

882378:RBRH RS07980
gene id: 882378:RBRH_RS07980
uniprot id: E5AS42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

882378:RBRH RS02260
gene id: 882378:RBRH_RS02260
uniprot id: E5AMZ4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

882378:RBRH RS03570
gene id: 882378:RBRH_RS03570
uniprot id: E5AP34
names: Similarity
messages: Belongs to the transglycosylase Slt family.

882378:RBRH RS05115
gene id: 882378:RBRH_RS05115
uniprot id: E5AQ28
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882378:RBRH RS03000
gene id: 882378:RBRH_RS03000
uniprot id: E5ANQ7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

882378:RBRH RS00515
gene id: 882378:RBRH_RS00515
uniprot id: E5AKJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

882378:RBRH RS02615
gene id: 882378:RBRH_RS02615
uniprot id: E5ANG8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

882378:RBRH RS05770
gene id: 882378:RBRH_RS05770
uniprot id: E5AQI2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

882378:RBRH RS11925
gene id: 882378:RBRH_RS11925
uniprot id: E5AN84
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

882378:RBRH RS03365
gene id: 882378:RBRH_RS03365
uniprot id: E5ANY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

882378:RBRH RS06200
gene id: 882378:RBRH_RS06200
uniprot id: E5AQT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

882378:RBRH RS01270
gene id: 882378:RBRH_RS01270
uniprot id: E5ALG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

882378:RBRH RS05190
gene id: 882378:RBRH_RS05190
uniprot id: E5AQ42
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

882378:RBRH RS00530
gene id: 882378:RBRH_RS00530
uniprot id: E5AKJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

882378:RBRH RS03665
gene id: 882378:RBRH_RS03665
uniprot id: E5AP55
names: Similarity
messages: Belongs to the GppA/Ppx family.

882378:RBRH RS00525
gene id: 882378:RBRH_RS00525
uniprot id: E5AKJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

882378:RBRH RS03685
gene id: 882378:RBRH_RS03685
uniprot id: E5AP59
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

882378:RBRH RS06410
gene id: 882378:RBRH_RS06410
uniprot id: E5AQY4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS02025
gene id: 882378:RBRH_RS02025
uniprot id: E5AMC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

882378:RBRH RS10945
gene id: 882378:RBRH_RS10945
uniprot id: E5ALT6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

882378:RBRH RS15870
gene id: 882378:RBRH_RS15870
uniprot id: E5AW77
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

882378:RBRH RS14550
gene id: 882378:RBRH_RS14550
uniprot id: E5AV94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882378:RBRH RS01600
gene id: 882378:RBRH_RS01600
uniprot id: E5AM32
names: Similarity
messages: Belongs to the transketolase family.

882378:RBRH RS15055
gene id: 882378:RBRH_RS15055
uniprot id: E5AVL7
names: Similarity
messages: Belongs to the ArsC family.

882378:RBRH RS10050
gene id: 882378:RBRH_RS10050
uniprot id: E5AKU3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882378:RBRH RS00345
gene id: 882378:RBRH_RS00345
uniprot id: E5AKE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

882378:RBRH RS10980
gene id: 882378:RBRH_RS10980
uniprot id: E5ALU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

882378:RBRH RS09320
gene id: 882378:RBRH_RS09320
uniprot id: E5AT58
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

882378:RBRH RS02645
gene id: 882378:RBRH_RS02645
uniprot id: E5ANH6
names: Similarity
messages: Belongs to the P(II) protein family.

882378:RBRH RS16065
gene id: 882378:RBRH_RS16065
uniprot id: E5AWC6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS04960
gene id: 882378:RBRH_RS04960
uniprot id: E5APZ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS00245
gene id: 882378:RBRH_RS00245
uniprot id: E5AKC6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

882378:RBRH RS10845
gene id: 882378:RBRH_RS10845
uniprot id: E5ALR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

882378:RBRH RS00460
gene id: 882378:RBRH_RS00460
uniprot id: E5AKH7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

882378:RBRH RS09410
gene id: 882378:RBRH_RS09410
uniprot id: E5AT79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

882378:RBRH RS09335
gene id: 882378:RBRH_RS09335
uniprot id: E5AT62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

882378:RBRH RS11810
gene id: 882378:RBRH_RS11810
uniprot id: E5AMS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882378:RBRH RS02815
gene id: 882378:RBRH_RS02815
uniprot id: E5ANL4
names: Similarity
messages: Belongs to the peptidase M1 family.

882378:RBRH RS04405
gene id: 882378:RBRH_RS04405
uniprot id: E5APM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

882378:RBRH RS12400
gene id: 882378:RBRH_RS12400
uniprot id: E5ATQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

882378:RBRH RS03625
gene id: 882378:RBRH_RS03625
uniprot id: E5AP47
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

882378:RBRH RS00235
gene id: 882378:RBRH_RS00235
uniprot id: E5AKC4
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS01630
gene id: 882378:RBRH_RS01630
uniprot id: E5AM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

882378:RBRH RS01095
gene id: 882378:RBRH_RS01095
uniprot id: E5ALD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

882378:RBRH RS08735
gene id: 882378:RBRH_RS08735
uniprot id: E5ASL4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS13950
gene id: 882378:RBRH_RS13950
uniprot id: E5AUV6
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS05910
gene id: 882378:RBRH_RS05910
uniprot id: E5AQL2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882378:RBRH RS08275
gene id: 882378:RBRH_RS08275
uniprot id: E5ASA6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

882378:RBRH RS01895
gene id: 882378:RBRH_RS01895
uniprot id: E5AM95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

882378:RBRH RS09950
gene id: 882378:RBRH_RS09950
uniprot id: E5AKS0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

882378:RBRH RS09065
gene id: 882378:RBRH_RS09065
uniprot id: E5ASU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882378:RBRH RS07605
gene id: 882378:RBRH_RS07605
uniprot id: E5ARU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

882378:RBRH RS09785
gene id: 882378:RBRH_RS09785
uniprot id: E5ATG4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

882378:RBRH RS12645
gene id: 882378:RBRH_RS12645
uniprot id: E5ATX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

882378:RBRH RS11015
gene id: 882378:RBRH_RS11015
uniprot id: E5ALV1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

882378:RBRH RS10320
gene id: 882378:RBRH_RS10320
uniprot id: E5AL08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

882378:RBRH RS09255
gene id: 882378:RBRH_RS09255
uniprot id: E5ASY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

882378:RBRH RS10170
gene id: 882378:RBRH_RS10170
uniprot id: E5AKX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

882378:RBRH RS03300
gene id: 882378:RBRH_RS03300
uniprot id: E5ANX2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

882378:RBRH RS11300
gene id: 882378:RBRH_RS11300
uniprot id: E5AMF4
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

882378:RBRH RS02810
gene id: 882378:RBRH_RS02810
uniprot id: E5ANL3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS03035
gene id: 882378:RBRH_RS03035
uniprot id: E5ANR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

882378:RBRH RS04520
gene id: 882378:RBRH_RS04520
uniprot id: E5APP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

882378:RBRH RS08285
gene id: 882378:RBRH_RS08285
uniprot id: E5ASA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

882378:RBRH RS08775
gene id: 882378:RBRH_RS08775
uniprot id: E5ASM2
names: Similarity
messages: Belongs to the TrpF family.

882378:RBRH RS05500
gene id: 882378:RBRH_RS05500
uniprot id: E5AQB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

882378:RBRH RS01880
gene id: 882378:RBRH_RS01880
uniprot id: E5AM92
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

882378:RBRH RS05850
gene id: 882378:RBRH_RS05850
uniprot id: E5AQK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

882378:RBRH RS09070
gene id: 882378:RBRH_RS09070
uniprot id: E5ASU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882378:RBRH RS01650
gene id: 882378:RBRH_RS01650
uniprot id: E5AM43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

882378:RBRH RS08755
gene id: 882378:RBRH_RS08755
uniprot id: E5ASL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

882378:RBRH RS00275
gene id: 882378:RBRH_RS00275
uniprot id: E5AKD2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

882378:RBRH RS05385
gene id: 882378:RBRH_RS05385
uniprot id: E5AQ88
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

882378:RBRH RS00485
gene id: 882378:RBRH_RS00485
uniprot id: E5AKI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

882378:RBRH RS04420
gene id: 882378:RBRH_RS04420
uniprot id: E5APM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

882378:RBRH RS13170
gene id: 882378:RBRH_RS13170
uniprot id: E5AUA6
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

882378:RBRH RS06495
gene id: 882378:RBRH_RS06495
uniprot id: E5AR00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

882378:RBRH RS16750
gene id: 882378:RBRH_RS16750
uniprot id: E5AT63
names: Function
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.

882378:RBRH RS06210
gene id: 882378:RBRH_RS06210
uniprot id: E5AQT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

882378:RBRH RS15020
gene id: 882378:RBRH_RS15020
uniprot id: E5AVK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

882378:RBRH RS12145
gene id: 882378:RBRH_RS12145
uniprot id: E5AND4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

882378:RBRH RS02305
gene id: 882378:RBRH_RS02305
uniprot id: E5AN05
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

882378:RBRH RS05725
gene id: 882378:RBRH_RS05725
uniprot id: E5AQH1
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

882378:RBRH RS03550
gene id: 882378:RBRH_RS03550
uniprot id: E5AP30
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

882378:RBRH RS03115
gene id: 882378:RBRH_RS03115
uniprot id: E5ANT1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

882378:RBRH RS14585
gene id: 882378:RBRH_RS14585
uniprot id: E5AVA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

882378:RBRH RS10425
gene id: 882378:RBRH_RS10425
uniprot id: E5AL30
names: Similarity
messages: Belongs to the PhoH family.

882378:RBRH RS04810
gene id: 882378:RBRH_RS04810
uniprot id: E5APW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

882378:RBRH RS01610
gene id: 882378:RBRH_RS01610
uniprot id: E5AM35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

882378:RBRH RS05325
gene id: 882378:RBRH_RS05325
uniprot id: E5AQ73
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

882378:RBRH RS20340
gene id: 882378:RBRH_RS20340
uniprot id: E5ALK6
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

882378:RBRH RS02285
gene id: 882378:RBRH_RS02285
uniprot id: E5AN01
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS04525
gene id: 882378:RBRH_RS04525
uniprot id: E5APQ0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

882378:RBRH RS12855
gene id: 882378:RBRH_RS12855
uniprot id: E5AU30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

882378:RBRH RS08365
gene id: 882378:RBRH_RS08365
uniprot id: E5ASC5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS14380
gene id: 882378:RBRH_RS14380
uniprot id: E5AV59
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

882378:RBRH RS00270
gene id: 882378:RBRH_RS00270
uniprot id: E5AKD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

882378:RBRH RS07210
gene id: 882378:RBRH_RS07210
uniprot id: E5ARI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

882378:RBRH RS04460
gene id: 882378:RBRH_RS04460
uniprot id: E5APN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

882378:RBRH RS12930
gene id: 882378:RBRH_RS12930
uniprot id: E5AU46
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882378:RBRH RS08395
gene id: 882378:RBRH_RS08395
uniprot id: E5ASD2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

882378:RBRH RS07585
gene id: 882378:RBRH_RS07585
uniprot id: E5ART7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882378:RBRH RS06265
gene id: 882378:RBRH_RS06265
uniprot id: E5AQU8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

882378:RBRH RS02965
gene id: 882378:RBRH_RS02965
uniprot id: E5ANQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

882378:RBRH RS05495
gene id: 882378:RBRH_RS05495
uniprot id: E5AQB7
names: Subcellular Location Annotation
messages: Periplasm

882378:RBRH RS02735
gene id: 882378:RBRH_RS02735
uniprot id: E5ANJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

882378:RBRH RS14930
gene id: 882378:RBRH_RS14930
uniprot id: E5AVI7
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

882378:RBRH RS12030
gene id: 882378:RBRH_RS12030
uniprot id: E5ANB2
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

882378:RBRH RS08300
gene id: 882378:RBRH_RS08300
uniprot id: E5ASB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

882378:RBRH RS02845
gene id: 882378:RBRH_RS02845
uniprot id: E5ANM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

882378:RBRH RS02740
gene id: 882378:RBRH_RS02740
uniprot id: E5ANJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

882378:RBRH RS03120
gene id: 882378:RBRH_RS03120
uniprot id: E5ANT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

882378:RBRH RS04570
gene id: 882378:RBRH_RS04570
uniprot id: E5APQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

882378:RBRH RS06780
gene id: 882378:RBRH_RS06780
uniprot id: E5AR72
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS01030
gene id: 882378:RBRH_RS01030
uniprot id: E5ALB6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882378:RBRH RS03240
gene id: 882378:RBRH_RS03240
uniprot id: E5ANV9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

882378:RBRH RS15060
gene id: 882378:RBRH_RS15060
uniprot id: E5AVL8
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

882378:RBRH RS04375
gene id: 882378:RBRH_RS04375
uniprot id: E5APL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

882378:RBRH RS03425
gene id: 882378:RBRH_RS03425
uniprot id: E5ANZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

882378:RBRH RS09080
gene id: 882378:RBRH_RS09080
uniprot id: E5ASU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882378:RBRH RS00415
gene id: 882378:RBRH_RS00415
uniprot id: E5AKG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

882378:RBRH RS13715
gene id: 882378:RBRH_RS13715
uniprot id: E5AUP4
names: Similarity
messages: Belongs to the malate synthase family.

882378:RBRH RS10025
gene id: 882378:RBRH_RS10025
uniprot id: E5AKT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

882378:RBRH RS02275
gene id: 882378:RBRH_RS02275
uniprot id: E5AMZ8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS03225
gene id: 882378:RBRH_RS03225
uniprot id: E5ANV6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

882378:RBRH RS14295
gene id: 882378:RBRH_RS14295
uniprot id: E5AV36
names: Biotechnology
names: Domain
names: Function
names: Similarity
messages: After addition of nuclear localization signals (NLS) and a transcription activation domain, can be expressed in both human and plant cells and will recognize and transcribe a target sequence; more than 17 core repeats are necessary for this function. The N-terminal cryptic repeats effect activation, while the C-terminal cryptic repeat is absolutely required. When fused to the FokI restriction endonuclease domain functions as a sequence-specific DNA nuclease in vitro (called TALE-nuclease, TALEN, PubMed:24792163 or BuDN, PubMed:25004980) and with an NLS, in human and yeast cells. The latter construct also allows targeted gene insertion. Modification of the core repeat BSR allows recognition of a user-defined DNA sequence, allowing these constructs to target and modify a DNA sequence of interest, and thus be used for genome engineering. Other potential uses as transcriptional repressors, for transposon targeting, DNA methylation or histone tail modifictions are also possible.
messages: Belongs to the transcription activator-like effector (TALE) family. Bat subfamily.
messages: Binds to dsDNA in a sequence-specific manner. Also binds a DNA/RNA duplex when the recognized sequence is in the DNA strand. Each tandem core repeat recognizes a single nucleotide in the target DNA via its base-specifying residue (BSR, residue 13 of each repeat); altering this amino acid changes sequence specificity.
messages: The protein is composed of 20 tandem core repeats (the BuD domain) with 1 base-specifying residue (BSR, residue 13), which recognizes 1 base pair in the target DNA.

882378:RBRH RS04450
gene id: 882378:RBRH_RS04450
uniprot id: E5APN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

882378:RBRH RS02670
gene id: 882378:RBRH_RS02670
uniprot id: E5ANI2
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

882378:RBRH RS09145
gene id: 882378:RBRH_RS09145
uniprot id: E5ASW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

882378:RBRH RS04735
gene id: 882378:RBRH_RS04735
uniprot id: E5APU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

882378:RBRH RS18985
gene id: 882378:RBRH_RS18985
uniprot id: E5AST9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882378:RBRH RS06500
gene id: 882378:RBRH_RS06500
uniprot id: E5AR02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

882378:RBRH RS03615
gene id: 882378:RBRH_RS03615
uniprot id: E5AP45
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS01405
gene id: 882378:RBRH_RS01405
uniprot id: E5ALI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

882378:RBRH RS01550
gene id: 882378:RBRH_RS01550
uniprot id: E5AM18
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS09915
gene id: 882378:RBRH_RS09915
uniprot id: E5ATJ5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

882378:RBRH RS10655
gene id: 882378:RBRH_RS10655
uniprot id: E5ALM1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

882378:RBRH RS06230
gene id: 882378:RBRH_RS06230
uniprot id: E5AQT9
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS05775
gene id: 882378:RBRH_RS05775
uniprot id: E5AQI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

882378:RBRH RS03800
gene id: 882378:RBRH_RS03800
uniprot id: E5AP90
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

882378:RBRH RS10675
gene id: 882378:RBRH_RS10675
uniprot id: E5ALM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

882378:RBRH RS01730
gene id: 882378:RBRH_RS01730
uniprot id: E5AM60
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS11410
gene id: 882378:RBRH_RS11410
uniprot id: E5AMI1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS08370
gene id: 882378:RBRH_RS08370
uniprot id: E5ASC6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

882378:RBRH RS04885
gene id: 882378:RBRH_RS04885
uniprot id: E5APX8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

882378:RBRH RS08655
gene id: 882378:RBRH_RS08655
uniprot id: E5ASJ5
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

882378:RBRH RS09020
gene id: 882378:RBRH_RS09020
uniprot id: E5AST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

882378:RBRH RS07720
gene id: 882378:RBRH_RS07720
uniprot id: E5ARX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

882378:RBRH RS13840
gene id: 882378:RBRH_RS13840
uniprot id: E5AUS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

882378:RBRH RS04760
gene id: 882378:RBRH_RS04760
uniprot id: E5APU9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

882378:RBRH RS03640
gene id: 882378:RBRH_RS03640
uniprot id: E5AP50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

882378:RBRH RS06075
gene id: 882378:RBRH_RS06075
uniprot id: E5AQP7
names: Similarity
messages: Belongs to the threonine synthase family.

882378:RBRH RS04510
gene id: 882378:RBRH_RS04510
uniprot id: E5APP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

882378:RBRH RS07900
gene id: 882378:RBRH_RS07900
uniprot id: E5AS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

882378:RBRH RS03630
gene id: 882378:RBRH_RS03630
uniprot id: E5AP48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

882378:RBRH RS14635
gene id: 882378:RBRH_RS14635
uniprot id: E5AVC0
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

882378:RBRH RS04540
gene id: 882378:RBRH_RS04540
uniprot id: E5APQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

882378:RBRH RS07710
gene id: 882378:RBRH_RS07710
uniprot id: E5ARX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

882378:RBRH RS09025
gene id: 882378:RBRH_RS09025
uniprot id: E5AST6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

882378:RBRH RS01285
gene id: 882378:RBRH_RS01285
uniprot id: E5ALG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

882378:RBRH RS10610
gene id: 882378:RBRH_RS10610
uniprot id: E5ALL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

882378:RBRH RS10755
gene id: 882378:RBRH_RS10755
uniprot id: E5ALP3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882378:RBRH RS12215
gene id: 882378:RBRH_RS12215
uniprot id: E5ANF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

882378:RBRH RS06475
gene id: 882378:RBRH_RS06475
uniprot id: E5AQZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

882378:RBRH RS09225
gene id: 882378:RBRH_RS09225
uniprot id: E5ASX6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

882378:RBRH RS01035
gene id: 882378:RBRH_RS01035
uniprot id: E5ALB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

882378:RBRH RS10740
gene id: 882378:RBRH_RS10740
uniprot id: E5ALP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

882378:RBRH RS00940
gene id: 882378:RBRH_RS00940
uniprot id: E5AL95
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

882378:RBRH RS02010
gene id: 882378:RBRH_RS02010
uniprot id: E5AMC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

882378:RBRH RS02020
gene id: 882378:RBRH_RS02020
uniprot id: E5AMC6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

882378:RBRH RS05825
gene id: 882378:RBRH_RS05825
uniprot id: E5AQJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

882378:RBRH RS10910
gene id: 882378:RBRH_RS10910
uniprot id: E5ALS8
names: Similarity
messages: Belongs to the DSD1 family.

882378:RBRH RS04465
gene id: 882378:RBRH_RS04465
uniprot id: E5APN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

882378:RBRH RS09900
gene id: 882378:RBRH_RS09900
uniprot id: E5ATJ2
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

882378:RBRH RS06670
gene id: 882378:RBRH_RS06670
uniprot id: E5AR42
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS07040
gene id: 882378:RBRH_RS07040
uniprot id: E5ARF1
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

882378:RBRH RS00605
gene id: 882378:RBRH_RS00605
uniprot id: E5AKL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

882378:RBRH RS11185
gene id: 882378:RBRH_RS11185
uniprot id: E5ALZ0
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS08135
gene id: 882378:RBRH_RS08135
uniprot id: E5AS77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

882378:RBRH RS14900
gene id: 882378:RBRH_RS14900
uniprot id: E5AVI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

882378:RBRH RS10920
gene id: 882378:RBRH_RS10920
uniprot id: E5ALT0
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS01785
gene id: 882378:RBRH_RS01785
uniprot id: E5AM72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

882378:RBRH RS08550
gene id: 882378:RBRH_RS08550
uniprot id: E5ASH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS11435
gene id: 882378:RBRH_RS11435
uniprot id: E5AMI6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882378:RBRH RS15325
gene id: 882378:RBRH_RS15325
uniprot id: E5AVU1
names: Similarity
messages: Belongs to the ParB family.

882378:RBRH RS13375
gene id: 882378:RBRH_RS13375
uniprot id: E5AUF7
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

882378:RBRH RS06205
gene id: 882378:RBRH_RS06205
uniprot id: E5AQT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

882378:RBRH RS09700
gene id: 882378:RBRH_RS09700
uniprot id: E5ATE4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

882378:RBRH RS04330
gene id: 882378:RBRH_RS04330
uniprot id: E5APK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

882378:RBRH RS05090
gene id: 882378:RBRH_RS05090
uniprot id: E5AQ23
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

882378:RBRH RS10020
gene id: 882378:RBRH_RS10020
uniprot id: E5AKT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

882378:RBRH RS13655
gene id: 882378:RBRH_RS13655
uniprot id: E5AUN3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

882378:RBRH RS06045
gene id: 882378:RBRH_RS06045
uniprot id: E5AQP1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

882378:RBRH RS01790
gene id: 882378:RBRH_RS01790
uniprot id: E5AM73
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

882378:RBRH RS10705
gene id: 882378:RBRH_RS10705
uniprot id: E5ALN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

882378:RBRH RS09140
gene id: 882378:RBRH_RS09140
uniprot id: E5ASW0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS00620
gene id: 882378:RBRH_RS00620
uniprot id: E5AKL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

882378:RBRH RS00990
gene id: 882378:RBRH_RS00990
uniprot id: E5ALA5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

882378:RBRH RS06455
gene id: 882378:RBRH_RS06455
uniprot id: E5AQZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

882378:RBRH RS08635
gene id: 882378:RBRH_RS08635
uniprot id: E5ASJ0
names: Similarity
messages: Belongs to the NodU/CmcH family.

882378:RBRH RS11805
gene id: 882378:RBRH_RS11805
uniprot id: E5AMS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882378:RBRH RS11080
gene id: 882378:RBRH_RS11080
uniprot id: E5ALW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

882378:RBRH RS02155
gene id: 882378:RBRH_RS02155
uniprot id: E5AMW7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

882378:RBRH RS07985
gene id: 882378:RBRH_RS07985
uniprot id: E5AS43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

882378:RBRH RS02755
gene id: 882378:RBRH_RS02755
uniprot id: E5ANK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

882378:RBRH RS09110
gene id: 882378:RBRH_RS09110
uniprot id: E5ASV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

882378:RBRH RS01240
gene id: 882378:RBRH_RS01240
uniprot id: E5ALF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

882378:RBRH RS10485
gene id: 882378:RBRH_RS10485
uniprot id: E5AL43
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

882378:RBRH RS06415
gene id: 882378:RBRH_RS06415
uniprot id: E5AQY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

882378:RBRH RS02030
gene id: 882378:RBRH_RS02030
uniprot id: E5AMC8
names: Similarity
messages: Belongs to the UPF0162 family.

882378:RBRH RS08195
gene id: 882378:RBRH_RS08195
uniprot id: E5AS89
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

882378:RBRH RS05890
gene id: 882378:RBRH_RS05890
uniprot id: E5AQK8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

882378:RBRH RS01360
gene id: 882378:RBRH_RS01360
uniprot id: E5ALI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

882378:RBRH RS00410
gene id: 882378:RBRH_RS00410
uniprot id: E5AKG3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

882378:RBRH RS08810
gene id: 882378:RBRH_RS08810
uniprot id: E5ASN1
names: Similarity
messages: Belongs to the citrate synthase family.

882378:RBRH RS13645
gene id: 882378:RBRH_RS13645
uniprot id: E5AUN1
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

882378:RBRH RS01775
gene id: 882378:RBRH_RS01775
uniprot id: E5AM70
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882378:RBRH RS02675
gene id: 882378:RBRH_RS02675
uniprot id: E5ANI3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882378:RBRH RS01310
gene id: 882378:RBRH_RS01310
uniprot id: E5ALH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

882378:RBRH RS13895
gene id: 882378:RBRH_RS13895
uniprot id: E5AUT8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

882378:RBRH RS01505
gene id: 882378:RBRH_RS01505
uniprot id: E5AM08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

882378:RBRH RS13455
gene id: 882378:RBRH_RS13455
uniprot id: E5AUI2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882378:RBRH RS11065
gene id: 882378:RBRH_RS11065
uniprot id: E5ALV8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

882378:RBRH RS12335
gene id: 882378:RBRH_RS12335
uniprot id: E5ATM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

882378:RBRH RS05650
gene id: 882378:RBRH_RS05650
uniprot id: E5AQF5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

882378:RBRH RS05815
gene id: 882378:RBRH_RS05815
uniprot id: E5AQJ3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

882378:RBRH RS04445
gene id: 882378:RBRH_RS04445
uniprot id: E5APN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

882378:RBRH RS05260
gene id: 882378:RBRH_RS05260
uniprot id: E5AQ59
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

882378:RBRH RS02175
gene id: 882378:RBRH_RS02175
uniprot id: E5AMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

882378:RBRH RS00300
gene id: 882378:RBRH_RS00300
uniprot id: E5AKD8
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

882378:RBRH RS11205
gene id: 882378:RBRH_RS11205
uniprot id: E5ALZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

882378:RBRH RS02750
gene id: 882378:RBRH_RS02750
uniprot id: E5ANK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

882378:RBRH RS02620
gene id: 882378:RBRH_RS02620
uniprot id: E5ANH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

882378:RBRH RS02255
gene id: 882378:RBRH_RS02255
uniprot id: E5AMZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

882378:RBRH RS00610
gene id: 882378:RBRH_RS00610
uniprot id: E5AKL5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

882378:RBRH RS08895
gene id: 882378:RBRH_RS08895
uniprot id: E5ASQ3
names: Subcellular Location Annotation
messages: Membrane

882378:RBRH RS04190
gene id: 882378:RBRH_RS04190
uniprot id: E5APH8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

882378:RBRH RS04305
gene id: 882378:RBRH_RS04305
uniprot id: E5APK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.