882083:SACMADRAFT RS24640
gene id: 882083:SACMADRAFT_RS24640
uniprot id: H5X302
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS19745
gene id: 882083:SACMADRAFT_RS19745
uniprot id: H5X4V1
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS04070
gene id: 882083:SACMADRAFT_RS04070
uniprot id: H5X898
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS30975
gene id: 882083:SACMADRAFT_RS30975
uniprot id: H5WWR0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS05725
gene id: 882083:SACMADRAFT_RS05725
uniprot id: H5WXC3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

882083:SACMADRAFT RS27295
gene id: 882083:SACMADRAFT_RS27295
uniprot id: H5XA32
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

882083:SACMADRAFT RS09950
gene id: 882083:SACMADRAFT_RS09950
uniprot id: H5X8J9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS22760
gene id: 882083:SACMADRAFT_RS22760
uniprot id: H5WWZ9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882083:SACMADRAFT RS03615
gene id: 882083:SACMADRAFT_RS03615
uniprot id: H5X775
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

882083:SACMADRAFT RS10970
gene id: 882083:SACMADRAFT_RS10970
uniprot id: H5XBI9
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS23660
gene id: 882083:SACMADRAFT_RS23660
uniprot id: H5X013
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

882083:SACMADRAFT RS08025
gene id: 882083:SACMADRAFT_RS08025
uniprot id: H5X3H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

882083:SACMADRAFT RS23820
gene id: 882083:SACMADRAFT_RS23820
uniprot id: H5X046
names: Similarity
messages: Belongs to the IucA/IucC family.

882083:SACMADRAFT RS21530
gene id: 882083:SACMADRAFT_RS21530
uniprot id: H5X9U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

882083:SACMADRAFT RS23455
gene id: 882083:SACMADRAFT_RS23455
uniprot id: H5WZ34
names: Similarity
messages: Belongs to the TPP enzyme family.

882083:SACMADRAFT RS07865
gene id: 882083:SACMADRAFT_RS07865
uniprot id: H5X3E9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS13860
gene id: 882083:SACMADRAFT_RS13860
uniprot id: H5X3Q4
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

882083:SACMADRAFT RS08705
gene id: 882083:SACMADRAFT_RS08705
uniprot id: H5X5H8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS10705
gene id: 882083:SACMADRAFT_RS10705
uniprot id: H5XBD8
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

882083:SACMADRAFT RS08455
gene id: 882083:SACMADRAFT_RS08455
uniprot id: H5X4J7
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS06905
gene id: 882083:SACMADRAFT_RS06905
uniprot id: H5X0G3
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

882083:SACMADRAFT RS17735
gene id: 882083:SACMADRAFT_RS17735
uniprot id: H5WYV6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882083:SACMADRAFT RS01850
gene id: 882083:SACMADRAFT_RS01850
uniprot id: H5X290
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

882083:SACMADRAFT RS16650
gene id: 882083:SACMADRAFT_RS16650
uniprot id: H5XBP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

882083:SACMADRAFT RS28305
gene id: 882083:SACMADRAFT_RS28305
uniprot id: H5WX41
names: Similarity
messages: Belongs to the ParB family.

882083:SACMADRAFT RS16345
gene id: 882083:SACMADRAFT_RS16345
uniprot id: H5XAQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS07275
gene id: 882083:SACMADRAFT_RS07275
uniprot id: H5X1H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

882083:SACMADRAFT RS22320
gene id: 882083:SACMADRAFT_RS22320
uniprot id: H5XBV6
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS28180
gene id: 882083:SACMADRAFT_RS28180
uniprot id: H5WX18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

882083:SACMADRAFT RS06575
gene id: 882083:SACMADRAFT_RS06575
uniprot id: H5WZG0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

882083:SACMADRAFT RS27035
gene id: 882083:SACMADRAFT_RS27035
uniprot id: H5X938
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

882083:SACMADRAFT RS08955
gene id: 882083:SACMADRAFT_RS08955
uniprot id: H5X6F2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

882083:SACMADRAFT RS15560
gene id: 882083:SACMADRAFT_RS15560
uniprot id: H5X8N5
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

882083:SACMADRAFT RS20970
gene id: 882083:SACMADRAFT_RS20970
uniprot id: H5X7X3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS09995
gene id: 882083:SACMADRAFT_RS09995
uniprot id: H5X9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS23960
gene id: 882083:SACMADRAFT_RS23960
uniprot id: H5X112
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

882083:SACMADRAFT RS10820
gene id: 882083:SACMADRAFT_RS10820
uniprot id: H5XBG2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

882083:SACMADRAFT RS23380
gene id: 882083:SACMADRAFT_RS23380
uniprot id: H5WZ19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

882083:SACMADRAFT RS10050
gene id: 882083:SACMADRAFT_RS10050
uniprot id: H5X9F0
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS08365
gene id: 882083:SACMADRAFT_RS08365
uniprot id: H5X4I0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

882083:SACMADRAFT RS02775
gene id: 882083:SACMADRAFT_RS02775
uniprot id: H5X4C5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

882083:SACMADRAFT RS13100
gene id: 882083:SACMADRAFT_RS13100
uniprot id: H5X1Q5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

882083:SACMADRAFT RS10105
gene id: 882083:SACMADRAFT_RS10105
uniprot id: H5X9G0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS03720
gene id: 882083:SACMADRAFT_RS03720
uniprot id: H5X796
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

882083:SACMADRAFT RS06345
gene id: 882083:SACMADRAFT_RS06345
uniprot id: H5WYI4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

882083:SACMADRAFT RS08095
gene id: 882083:SACMADRAFT_RS08095
uniprot id: H5X3J3
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS07970
gene id: 882083:SACMADRAFT_RS07970
uniprot id: H5X3H1
names: Similarity
messages: Belongs to the FPG family.

882083:SACMADRAFT RS04965
gene id: 882083:SACMADRAFT_RS04965
uniprot id: H5XB71
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

882083:SACMADRAFT RS13395
gene id: 882083:SACMADRAFT_RS13395
uniprot id: H5X2N6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

882083:SACMADRAFT RS26465
gene id: 882083:SACMADRAFT_RS26465
uniprot id: H5X804
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
messages: Homodimer.

882083:SACMADRAFT RS28115
gene id: 882083:SACMADRAFT_RS28115
uniprot id: H5XC54
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS02500
gene id: 882083:SACMADRAFT_RS02500
uniprot id: H5X470
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

882083:SACMADRAFT RS02550
gene id: 882083:SACMADRAFT_RS02550
uniprot id: H5X479
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

882083:SACMADRAFT RS26180
gene id: 882083:SACMADRAFT_RS26180
uniprot id: H5X719
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882083:SACMADRAFT RS05110
gene id: 882083:SACMADRAFT_RS05110
uniprot id: H5XBA0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS09445
gene id: 882083:SACMADRAFT_RS09445
uniprot id: H5X7H5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

882083:SACMADRAFT RS12075
gene id: 882083:SACMADRAFT_RS12075
uniprot id: H5WYQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

882083:SACMADRAFT RS19855
gene id: 882083:SACMADRAFT_RS19855
uniprot id: H5X4X4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

882083:SACMADRAFT RS10375
gene id: 882083:SACMADRAFT_RS10375
uniprot id: H5XAE9
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS13660
gene id: 882083:SACMADRAFT_RS13660
uniprot id: H5X3L5
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

882083:SACMADRAFT RS27135
gene id: 882083:SACMADRAFT_RS27135
uniprot id: H5XA01
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

882083:SACMADRAFT RS20770
gene id: 882083:SACMADRAFT_RS20770
uniprot id: H5X7T6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

882083:SACMADRAFT RS18055
gene id: 882083:SACMADRAFT_RS18055
uniprot id: H5WZV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

882083:SACMADRAFT RS09360
gene id: 882083:SACMADRAFT_RS09360
uniprot id: H5X7F9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

882083:SACMADRAFT RS22240
gene id: 882083:SACMADRAFT_RS22240
uniprot id: H5XBT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

882083:SACMADRAFT RS16240
gene id: 882083:SACMADRAFT_RS16240
uniprot id: H5XAN5
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

882083:SACMADRAFT RS21955
gene id: 882083:SACMADRAFT_RS21955
uniprot id: H5XAW0
names: Similarity
messages: Belongs to the asp23 family.

882083:SACMADRAFT RS17915
gene id: 882083:SACMADRAFT_RS17915
uniprot id: H5WZS6
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS02130
gene id: 882083:SACMADRAFT_RS02130
uniprot id: H5X371
names: Similarity
messages: Belongs to the AHA1 family.

882083:SACMADRAFT RS27590
gene id: 882083:SACMADRAFT_RS27590
uniprot id: H5XB23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

882083:SACMADRAFT RS05540
gene id: 882083:SACMADRAFT_RS05540
uniprot id: H5WWD3
names: Similarity
messages: Belongs to the HypE family.

882083:SACMADRAFT RS27635
gene id: 882083:SACMADRAFT_RS27635
uniprot id: H5XB32
names: Similarity
messages: Belongs to the UPF0098 family.

882083:SACMADRAFT RS01215
gene id: 882083:SACMADRAFT_RS01215
uniprot id: H5X097
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

882083:SACMADRAFT RS02715
gene id: 882083:SACMADRAFT_RS02715
uniprot id: H5X4B3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

882083:SACMADRAFT RS05800
gene id: 882083:SACMADRAFT_RS05800
uniprot id: H5WXE1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

882083:SACMADRAFT RS06445
gene id: 882083:SACMADRAFT_RS06445
uniprot id: H5WZD4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

882083:SACMADRAFT RS18580
gene id: 882083:SACMADRAFT_RS18580
uniprot id: H5X0Z6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

882083:SACMADRAFT RS20185
gene id: 882083:SACMADRAFT_RS20185
uniprot id: H5X5W5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

882083:SACMADRAFT RS04735
gene id: 882083:SACMADRAFT_RS04735
uniprot id: H5XA94
names: Similarity
messages: Belongs to the Nudix hydrolase family.

882083:SACMADRAFT RS14195
gene id: 882083:SACMADRAFT_RS14195
uniprot id: H5X4Q7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS27385
gene id: 882083:SACMADRAFT_RS27385
uniprot id: H5XA50
names: Similarity
messages: Belongs to the EspG family.

882083:SACMADRAFT RS03335
gene id: 882083:SACMADRAFT_RS03335
uniprot id: H5X691
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

882083:SACMADRAFT RS11565
gene id: 882083:SACMADRAFT_RS11565
uniprot id: H5WXL2
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

882083:SACMADRAFT RS03370
gene id: 882083:SACMADRAFT_RS03370
uniprot id: H5X698
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

882083:SACMADRAFT RS24105
gene id: 882083:SACMADRAFT_RS24105
uniprot id: H5X137
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

882083:SACMADRAFT RS11095
gene id: 882083:SACMADRAFT_RS11095
uniprot id: H5WWG5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

882083:SACMADRAFT RS06630
gene id: 882083:SACMADRAFT_RS06630
uniprot id: H5WZH1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

882083:SACMADRAFT RS16165
gene id: 882083:SACMADRAFT_RS16165
uniprot id: H5XAM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

882083:SACMADRAFT RS19630
gene id: 882083:SACMADRAFT_RS19630
uniprot id: H5X3Z0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882083:SACMADRAFT RS19810
gene id: 882083:SACMADRAFT_RS19810
uniprot id: H5X4W5
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS12975
gene id: 882083:SACMADRAFT_RS12975
uniprot id: H5X1N0
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

882083:SACMADRAFT RS24030
gene id: 882083:SACMADRAFT_RS24030
uniprot id: H5X124
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

882083:SACMADRAFT RS16185
gene id: 882083:SACMADRAFT_RS16185
uniprot id: H5XAM4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

882083:SACMADRAFT RS21145
gene id: 882083:SACMADRAFT_RS21145
uniprot id: H5X8T2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

882083:SACMADRAFT RS19685
gene id: 882083:SACMADRAFT_RS19685
uniprot id: H5X4U0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS01335
gene id: 882083:SACMADRAFT_RS01335
uniprot id: H5X0C3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

882083:SACMADRAFT RS08205
gene id: 882083:SACMADRAFT_RS08205
uniprot id: H5X4E8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

882083:SACMADRAFT RS11485
gene id: 882083:SACMADRAFT_RS11485
uniprot id: H5WXJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS16320
gene id: 882083:SACMADRAFT_RS16320
uniprot id: H5XAQ1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

882083:SACMADRAFT RS23245
gene id: 882083:SACMADRAFT_RS23245
uniprot id: H5WYZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

882083:SACMADRAFT RS00010
gene id: 882083:SACMADRAFT_RS00010
uniprot id: H5WX50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

882083:SACMADRAFT RS03390
gene id: 882083:SACMADRAFT_RS03390
uniprot id: H5X6A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

882083:SACMADRAFT RS11025
gene id: 882083:SACMADRAFT_RS11025
uniprot id: H5XBK0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

882083:SACMADRAFT RS15030
gene id: 882083:SACMADRAFT_RS15030
uniprot id: H5X7L1
names: Similarity
messages: Belongs to the CapA family.

882083:SACMADRAFT RS23595
gene id: 882083:SACMADRAFT_RS23595
uniprot id: H5X000
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS11120
gene id: 882083:SACMADRAFT_RS11120
uniprot id: H5WWH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

882083:SACMADRAFT RS08055
gene id: 882083:SACMADRAFT_RS08055
uniprot id: H5X3I5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

882083:SACMADRAFT RS09195
gene id: 882083:SACMADRAFT_RS09195
uniprot id: H5X6K1
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS15450
gene id: 882083:SACMADRAFT_RS15450
uniprot id: H5X8L4
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS06720
gene id: 882083:SACMADRAFT_RS06720
uniprot id: H5WZI9
names: Similarity
messages: Belongs to the DprA/Smf family.

882083:SACMADRAFT RS00970
gene id: 882083:SACMADRAFT_RS00970
uniprot id: H5WZA5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

882083:SACMADRAFT RS18095
gene id: 882083:SACMADRAFT_RS18095
uniprot id: H5WZW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

882083:SACMADRAFT RS20165
gene id: 882083:SACMADRAFT_RS20165
uniprot id: H5X5W1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

882083:SACMADRAFT RS22925
gene id: 882083:SACMADRAFT_RS22925
uniprot id: H5WXZ2
names: Similarity
messages: Belongs to the CsoR family.

882083:SACMADRAFT RS02800
gene id: 882083:SACMADRAFT_RS02800
uniprot id: H5X4D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882083:SACMADRAFT RS01450
gene id: 882083:SACMADRAFT_RS01450
uniprot id: H5X181
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

882083:SACMADRAFT RS02840
gene id: 882083:SACMADRAFT_RS02840
uniprot id: H5X570
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

882083:SACMADRAFT RS12530
gene id: 882083:SACMADRAFT_RS12530
uniprot id: H5X0K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

882083:SACMADRAFT RS08865
gene id: 882083:SACMADRAFT_RS08865
uniprot id: H5X5L0
names: Similarity
messages: Belongs to the peptidase S8 family.

882083:SACMADRAFT RS24020
gene id: 882083:SACMADRAFT_RS24020
uniprot id: H5X123
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

882083:SACMADRAFT RS11925
gene id: 882083:SACMADRAFT_RS11925
uniprot id: H5WYM3
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

882083:SACMADRAFT RS28280
gene id: 882083:SACMADRAFT_RS28280
uniprot id: H5WX36
names: Similarity
messages: Belongs to the thioredoxin family.

882083:SACMADRAFT RS14260
gene id: 882083:SACMADRAFT_RS14260
uniprot id: H5X4S0
names: Similarity
messages: Belongs to the AHA1 family.

882083:SACMADRAFT RS18180
gene id: 882083:SACMADRAFT_RS18180
uniprot id: H5WZX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

882083:SACMADRAFT RS13670
gene id: 882083:SACMADRAFT_RS13670
uniprot id: H5X3L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

882083:SACMADRAFT RS07335
gene id: 882083:SACMADRAFT_RS07335
uniprot id: H5X1I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

882083:SACMADRAFT RS17640
gene id: 882083:SACMADRAFT_RS17640
uniprot id: H5WYT7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS24885
gene id: 882083:SACMADRAFT_RS24885
uniprot id: H5X351
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS20590
gene id: 882083:SACMADRAFT_RS20590
uniprot id: H5X6W9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

882083:SACMADRAFT RS17225
gene id: 882083:SACMADRAFT_RS17225
uniprot id: H5WXR9
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS09510
gene id: 882083:SACMADRAFT_RS09510
uniprot id: H5X7J0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS07195
gene id: 882083:SACMADRAFT_RS07195
uniprot id: H5X1F4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS02890
gene id: 882083:SACMADRAFT_RS02890
uniprot id: H5X580
names: Cofactor
messages: Binds 1 zinc ion per subunit.

882083:SACMADRAFT RS24350
gene id: 882083:SACMADRAFT_RS24350
uniprot id: H5X216
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

882083:SACMADRAFT RS17330
gene id: 882083:SACMADRAFT_RS17330
uniprot id: H5WXU0
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

882083:SACMADRAFT RS14295
gene id: 882083:SACMADRAFT_RS14295
uniprot id: H5X4S4
names: Similarity
messages: Belongs to the YciI family.

882083:SACMADRAFT RS15020
gene id: 882083:SACMADRAFT_RS15020
uniprot id: H5X7K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS06590
gene id: 882083:SACMADRAFT_RS06590
uniprot id: H5WZG3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

882083:SACMADRAFT RS28315
gene id: 882083:SACMADRAFT_RS28315
uniprot id: H5WX43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

882083:SACMADRAFT RS14120
gene id: 882083:SACMADRAFT_RS14120
uniprot id: H5X4P2
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

882083:SACMADRAFT RS04390
gene id: 882083:SACMADRAFT_RS04390
uniprot id: H5X987
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS22605
gene id: 882083:SACMADRAFT_RS22605
uniprot id: H5WWW9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

882083:SACMADRAFT RS18620
gene id: 882083:SACMADRAFT_RS18620
uniprot id: H5X1T6
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

882083:SACMADRAFT RS11745
gene id: 882083:SACMADRAFT_RS11745
uniprot id: H5WXP9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882083:SACMADRAFT RS14680
gene id: 882083:SACMADRAFT_RS14680
uniprot id: H5X6L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

882083:SACMADRAFT RS23465
gene id: 882083:SACMADRAFT_RS23465
uniprot id: H5WZ36
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

882083:SACMADRAFT RS27825
gene id: 882083:SACMADRAFT_RS27825
uniprot id: H5XB68
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

882083:SACMADRAFT RS07580
gene id: 882083:SACMADRAFT_RS07580
uniprot id: H5X2G1
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

882083:SACMADRAFT RS06330
gene id: 882083:SACMADRAFT_RS06330
uniprot id: H5WYI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

882083:SACMADRAFT RS06960
gene id: 882083:SACMADRAFT_RS06960
uniprot id: H5X0H4
names: Similarity
messages: Belongs to the CdaR family.

882083:SACMADRAFT RS20090
gene id: 882083:SACMADRAFT_RS20090
uniprot id: H5X5U6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

882083:SACMADRAFT RS23060
gene id: 882083:SACMADRAFT_RS23060
uniprot id: H5WY19
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882083:SACMADRAFT RS26725
gene id: 882083:SACMADRAFT_RS26725
uniprot id: H5X847
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

882083:SACMADRAFT RS20640
gene id: 882083:SACMADRAFT_RS20640
uniprot id: H5X6X9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

882083:SACMADRAFT RS03460
gene id: 882083:SACMADRAFT_RS03460
uniprot id: H5X6B7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

882083:SACMADRAFT RS10635
gene id: 882083:SACMADRAFT_RS10635
uniprot id: H5XAK1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

882083:SACMADRAFT RS05905
gene id: 882083:SACMADRAFT_RS05905
uniprot id: H5WXG2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS09665
gene id: 882083:SACMADRAFT_RS09665
uniprot id: H5X8E3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS26925
gene id: 882083:SACMADRAFT_RS26925
uniprot id: H5X916
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

882083:SACMADRAFT RS18820
gene id: 882083:SACMADRAFT_RS18820
uniprot id: H5X1X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

882083:SACMADRAFT RS02765
gene id: 882083:SACMADRAFT_RS02765
uniprot id: H5X4C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882083:SACMADRAFT RS18835
gene id: 882083:SACMADRAFT_RS18835
uniprot id: H5X1Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

882083:SACMADRAFT RS20750
gene id: 882083:SACMADRAFT_RS20750
uniprot id: H5X7T2
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

882083:SACMADRAFT RS27500
gene id: 882083:SACMADRAFT_RS27500
uniprot id: H5XB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS23160
gene id: 882083:SACMADRAFT_RS23160
uniprot id: H5WY42
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS18170
gene id: 882083:SACMADRAFT_RS18170
uniprot id: H5WZX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

882083:SACMADRAFT RS24890
gene id: 882083:SACMADRAFT_RS24890
uniprot id: H5X352
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS27790
gene id: 882083:SACMADRAFT_RS27790
uniprot id: H5XB61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

882083:SACMADRAFT RS09025
gene id: 882083:SACMADRAFT_RS09025
uniprot id: H5X6G6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

882083:SACMADRAFT RS11030
gene id: 882083:SACMADRAFT_RS11030
uniprot id: H5XBK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS17910
gene id: 882083:SACMADRAFT_RS17910
uniprot id: H5WZS5
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

882083:SACMADRAFT RS04025
gene id: 882083:SACMADRAFT_RS04025
uniprot id: H5X888
names: Similarity
messages: Belongs to the peptidase S11 family.

882083:SACMADRAFT RS02980
gene id: 882083:SACMADRAFT_RS02980
uniprot id: H5X598
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

882083:SACMADRAFT RS26285
gene id: 882083:SACMADRAFT_RS26285
uniprot id: H5X737
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS09035
gene id: 882083:SACMADRAFT_RS09035
uniprot id: H5X6G8
names: Similarity
messages: Belongs to the serpin family.

882083:SACMADRAFT RS00015
gene id: 882083:SACMADRAFT_RS00015
uniprot id: H5WX51
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

882083:SACMADRAFT RS13185
gene id: 882083:SACMADRAFT_RS13185
uniprot id: H5X1S2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882083:SACMADRAFT RS04995
gene id: 882083:SACMADRAFT_RS04995
uniprot id: H5XB77
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS26920
gene id: 882083:SACMADRAFT_RS26920
uniprot id: H5X915
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

882083:SACMADRAFT RS13565
gene id: 882083:SACMADRAFT_RS13565
uniprot id: H5X2S0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS19040
gene id: 882083:SACMADRAFT_RS19040
uniprot id: H5X2U8
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

882083:SACMADRAFT RS18205
gene id: 882083:SACMADRAFT_RS18205
uniprot id: H5WZY3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS04510
gene id: 882083:SACMADRAFT_RS04510
uniprot id: H5X9B1
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

882083:SACMADRAFT RS21045
gene id: 882083:SACMADRAFT_RS21045
uniprot id: H5X7Y7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

882083:SACMADRAFT RS10065
gene id: 882083:SACMADRAFT_RS10065
uniprot id: H5X9F3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS01360
gene id: 882083:SACMADRAFT_RS01360
uniprot id: H5X0C7
names: Similarity
messages: Belongs to the FPG family.

882083:SACMADRAFT RS07740
gene id: 882083:SACMADRAFT_RS07740
uniprot id: H5X2J3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

882083:SACMADRAFT RS12745
gene id: 882083:SACMADRAFT_RS12745
uniprot id: H5X0Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS13630
gene id: 882083:SACMADRAFT_RS13630
uniprot id: H5X3K9
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS06670
gene id: 882083:SACMADRAFT_RS06670
uniprot id: H5WZH9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

882083:SACMADRAFT RS13635
gene id: 882083:SACMADRAFT_RS13635
uniprot id: H5X3L0
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS00175
gene id: 882083:SACMADRAFT_RS00175
uniprot id: H5WX78
names: Similarity
messages: Belongs to the peptidase C40 family.

882083:SACMADRAFT RS02365
gene id: 882083:SACMADRAFT_RS02365
uniprot id: H5X3B7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

882083:SACMADRAFT RS11735
gene id: 882083:SACMADRAFT_RS11735
uniprot id: H5WXP7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS12380
gene id: 882083:SACMADRAFT_RS12380
uniprot id: H5WZP4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS18000
gene id: 882083:SACMADRAFT_RS18000
uniprot id: H5WZU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

882083:SACMADRAFT RS19210
gene id: 882083:SACMADRAFT_RS19210
uniprot id: H5X2Y0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

882083:SACMADRAFT RS05980
gene id: 882083:SACMADRAFT_RS05980
uniprot id: H5WXH7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

882083:SACMADRAFT RS04075
gene id: 882083:SACMADRAFT_RS04075
uniprot id: H5X899
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS06385
gene id: 882083:SACMADRAFT_RS06385
uniprot id: H5WYJ2
names: Similarity
messages: Belongs to the arginase family.

882083:SACMADRAFT RS03420
gene id: 882083:SACMADRAFT_RS03420
uniprot id: H5X6A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

882083:SACMADRAFT RS15145
gene id: 882083:SACMADRAFT_RS15145
uniprot id: H5X7N5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

882083:SACMADRAFT RS02605
gene id: 882083:SACMADRAFT_RS02605
uniprot id: H5X491
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

882083:SACMADRAFT RS02785
gene id: 882083:SACMADRAFT_RS02785
uniprot id: H5X4C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

882083:SACMADRAFT RS17820
gene id: 882083:SACMADRAFT_RS17820
uniprot id: H5WYX2
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS02210
gene id: 882083:SACMADRAFT_RS02210
uniprot id: H5X386
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS23665
gene id: 882083:SACMADRAFT_RS23665
uniprot id: H5X014
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

882083:SACMADRAFT RS15685
gene id: 882083:SACMADRAFT_RS15685
uniprot id: H5X8Q8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

882083:SACMADRAFT RS04715
gene id: 882083:SACMADRAFT_RS04715
uniprot id: H5XA90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

882083:SACMADRAFT RS01725
gene id: 882083:SACMADRAFT_RS01725
uniprot id: H5X1D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS10730
gene id: 882083:SACMADRAFT_RS10730
uniprot id: H5XBE3
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

882083:SACMADRAFT RS14875
gene id: 882083:SACMADRAFT_RS14875
uniprot id: H5X6Q0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS02035
gene id: 882083:SACMADRAFT_RS02035
uniprot id: H5X2C5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

882083:SACMADRAFT RS18800
gene id: 882083:SACMADRAFT_RS18800
uniprot id: H5X1X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

882083:SACMADRAFT RS19915
gene id: 882083:SACMADRAFT_RS19915
uniprot id: H5X4Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

882083:SACMADRAFT RS19415
gene id: 882083:SACMADRAFT_RS19415
uniprot id: H5X3U8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

882083:SACMADRAFT RS10265
gene id: 882083:SACMADRAFT_RS10265
uniprot id: H5X9J2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS12690
gene id: 882083:SACMADRAFT_RS12690
uniprot id: H5X0P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

882083:SACMADRAFT RS27025
gene id: 882083:SACMADRAFT_RS27025
uniprot id: H5X936
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

882083:SACMADRAFT RS21585
gene id: 882083:SACMADRAFT_RS21585
uniprot id: H5X9W0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

882083:SACMADRAFT RS19255
gene id: 882083:SACMADRAFT_RS19255
uniprot id: H5X2Y9
names: Similarity
messages: Belongs to the DEAD box helicase family.

882083:SACMADRAFT RS01490
gene id: 882083:SACMADRAFT_RS01490
uniprot id: H5X190
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

882083:SACMADRAFT RS11670
gene id: 882083:SACMADRAFT_RS11670
uniprot id: H5WXN4
names: Similarity
messages: Belongs to the Fur family.

882083:SACMADRAFT RS16905
gene id: 882083:SACMADRAFT_RS16905
uniprot id: H5WWQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS31055
gene id: 882083:SACMADRAFT_RS31055
uniprot id: H5WXY4
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

882083:SACMADRAFT RS10720
gene id: 882083:SACMADRAFT_RS10720
uniprot id: H5XBE1
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS07665
gene id: 882083:SACMADRAFT_RS07665
uniprot id: H5X2H8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS16735
gene id: 882083:SACMADRAFT_RS16735
uniprot id: H5XBR4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS01970
gene id: 882083:SACMADRAFT_RS01970
uniprot id: H5X2B3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS07540
gene id: 882083:SACMADRAFT_RS07540
uniprot id: H5X2F3
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

882083:SACMADRAFT RS15900
gene id: 882083:SACMADRAFT_RS15900
uniprot id: H5X9N3
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS11110
gene id: 882083:SACMADRAFT_RS11110
uniprot id: H5WWG8
names: Similarity
messages: Belongs to the glutamine synthetase family.

882083:SACMADRAFT RS00550
gene id: 882083:SACMADRAFT_RS00550
uniprot id: H5WY96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

882083:SACMADRAFT RS03570
gene id: 882083:SACMADRAFT_RS03570
uniprot id: H5X766
names: Similarity
messages: Belongs to the peptidase S8 family.

882083:SACMADRAFT RS17215
gene id: 882083:SACMADRAFT_RS17215
uniprot id: H5WXR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

882083:SACMADRAFT RS21815
gene id: 882083:SACMADRAFT_RS21815
uniprot id: H5XAT2
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

882083:SACMADRAFT RS23850
gene id: 882083:SACMADRAFT_RS23850
uniprot id: H5X052
names: Similarity
messages: Belongs to the peptidase S8 family.

882083:SACMADRAFT RS19205
gene id: 882083:SACMADRAFT_RS19205
uniprot id: H5X2X9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

882083:SACMADRAFT RS10490
gene id: 882083:SACMADRAFT_RS10490
uniprot id: H5XAH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

882083:SACMADRAFT RS27850
gene id: 882083:SACMADRAFT_RS27850
uniprot id: H5XBZ9
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS00920
gene id: 882083:SACMADRAFT_RS00920
uniprot id: H5WZ98
names: Similarity
messages: Belongs to the AHA1 family.

882083:SACMADRAFT RS27070
gene id: 882083:SACMADRAFT_RS27070
uniprot id: H5X945
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

882083:SACMADRAFT RS16205
gene id: 882083:SACMADRAFT_RS16205
uniprot id: H5XAM8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS21825
gene id: 882083:SACMADRAFT_RS21825
uniprot id: H5XAT4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

882083:SACMADRAFT RS12030
gene id: 882083:SACMADRAFT_RS12030
uniprot id: H5WYP4
names: Similarity
messages: Belongs to the peptidase M1 family.

882083:SACMADRAFT RS03610
gene id: 882083:SACMADRAFT_RS03610
uniprot id: H5X774
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

882083:SACMADRAFT RS22220
gene id: 882083:SACMADRAFT_RS22220
uniprot id: H5XBT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

882083:SACMADRAFT RS28300
gene id: 882083:SACMADRAFT_RS28300
uniprot id: H5WX40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

882083:SACMADRAFT RS09630
gene id: 882083:SACMADRAFT_RS09630
uniprot id: H5X8D6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS11675
gene id: 882083:SACMADRAFT_RS11675
uniprot id: H5WXN5
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS10255
gene id: 882083:SACMADRAFT_RS10255
uniprot id: H5X9J0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

882083:SACMADRAFT RS23530
gene id: 882083:SACMADRAFT_RS23530
uniprot id: H5WZ54
names: Similarity
messages: Belongs to the AAA ATPase family.

882083:SACMADRAFT RS03400
gene id: 882083:SACMADRAFT_RS03400
uniprot id: H5X6A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

882083:SACMADRAFT RS19890
gene id: 882083:SACMADRAFT_RS19890
uniprot id: H5X4Y1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

882083:SACMADRAFT RS00870
gene id: 882083:SACMADRAFT_RS00870
uniprot id: H5WZ88
names: Similarity
messages: Belongs to the AHA1 family.

882083:SACMADRAFT RS13960
gene id: 882083:SACMADRAFT_RS13960
uniprot id: H5X3S3
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

882083:SACMADRAFT RS06965
gene id: 882083:SACMADRAFT_RS06965
uniprot id: H5X0H5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

882083:SACMADRAFT RS01040
gene id: 882083:SACMADRAFT_RS01040
uniprot id: H5WZB9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

882083:SACMADRAFT RS03415
gene id: 882083:SACMADRAFT_RS03415
uniprot id: H5X6A7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

882083:SACMADRAFT RS10385
gene id: 882083:SACMADRAFT_RS10385
uniprot id: H5XAF1
names: Similarity
messages: Belongs to the ribF family.

882083:SACMADRAFT RS06940
gene id: 882083:SACMADRAFT_RS06940
uniprot id: H5X0H0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

882083:SACMADRAFT RS05930
gene id: 882083:SACMADRAFT_RS05930
uniprot id: H5WXG7
names: Similarity
messages: Belongs to the CobH/CbiC family.

882083:SACMADRAFT RS02810
gene id: 882083:SACMADRAFT_RS02810
uniprot id: H5X4D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

882083:SACMADRAFT RS14755
gene id: 882083:SACMADRAFT_RS14755
uniprot id: H5X6M6
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

882083:SACMADRAFT RS06945
gene id: 882083:SACMADRAFT_RS06945
uniprot id: H5X0H1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

882083:SACMADRAFT RS03235
gene id: 882083:SACMADRAFT_RS03235
uniprot id: H5X672
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

882083:SACMADRAFT RS18125
gene id: 882083:SACMADRAFT_RS18125
uniprot id: H5WZW7
names: Similarity
messages: Belongs to the YggT family.

882083:SACMADRAFT RS11450
gene id: 882083:SACMADRAFT_RS11450
uniprot id: H5WXJ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS14890
gene id: 882083:SACMADRAFT_RS14890
uniprot id: H5X6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS18315
gene id: 882083:SACMADRAFT_RS18315
uniprot id: H5X0U2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

882083:SACMADRAFT RS12400
gene id: 882083:SACMADRAFT_RS12400
uniprot id: H5WZP8
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS01495
gene id: 882083:SACMADRAFT_RS01495
uniprot id: H5X191
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

882083:SACMADRAFT RS21425
gene id: 882083:SACMADRAFT_RS21425
uniprot id: H5X8Z1
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS06025
gene id: 882083:SACMADRAFT_RS06025
uniprot id: H5WYC4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS18910
gene id: 882083:SACMADRAFT_RS18910
uniprot id: H5X1Z4
names: Similarity
messages: Belongs to the creatininase superfamily.

882083:SACMADRAFT RS19405
gene id: 882083:SACMADRAFT_RS19405
uniprot id: H5X3U6
names: Similarity
messages: Belongs to the archease family.

882083:SACMADRAFT RS00290
gene id: 882083:SACMADRAFT_RS00290
uniprot id: H5WXA1
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS03515
gene id: 882083:SACMADRAFT_RS03515
uniprot id: H5X6C8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

882083:SACMADRAFT RS06200
gene id: 882083:SACMADRAFT_RS06200
uniprot id: H5WYF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

882083:SACMADRAFT RS26945
gene id: 882083:SACMADRAFT_RS26945
uniprot id: H5X920
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

882083:SACMADRAFT RS19905
gene id: 882083:SACMADRAFT_RS19905
uniprot id: H5X4Y4
names: Similarity
messages: Belongs to the peptidase S58 family.

882083:SACMADRAFT RS23340
gene id: 882083:SACMADRAFT_RS23340
uniprot id: H5WZ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

882083:SACMADRAFT RS24160
gene id: 882083:SACMADRAFT_RS24160
uniprot id: H5X148
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

882083:SACMADRAFT RS19570
gene id: 882083:SACMADRAFT_RS19570
uniprot id: H5X3X8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

882083:SACMADRAFT RS13340
gene id: 882083:SACMADRAFT_RS13340
uniprot id: H5X2M7
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS23650
gene id: 882083:SACMADRAFT_RS23650
uniprot id: H5X011
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

882083:SACMADRAFT RS06640
gene id: 882083:SACMADRAFT_RS06640
uniprot id: H5WZH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

882083:SACMADRAFT RS18335
gene id: 882083:SACMADRAFT_RS18335
uniprot id: H5X0U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

882083:SACMADRAFT RS07205
gene id: 882083:SACMADRAFT_RS07205
uniprot id: H5X1F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS18120
gene id: 882083:SACMADRAFT_RS18120
uniprot id: H5WZW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

882083:SACMADRAFT RS08150
gene id: 882083:SACMADRAFT_RS08150
uniprot id: H5X4D7
names: Similarity
messages: Belongs to the DapA family.

882083:SACMADRAFT RS27485
gene id: 882083:SACMADRAFT_RS27485
uniprot id: H5XB01
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS02670
gene id: 882083:SACMADRAFT_RS02670
uniprot id: H5X4A4
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS11005
gene id: 882083:SACMADRAFT_RS11005
uniprot id: H5XBJ6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS18805
gene id: 882083:SACMADRAFT_RS18805
uniprot id: H5X1X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

882083:SACMADRAFT RS13020
gene id: 882083:SACMADRAFT_RS13020
uniprot id: H5X1N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS02755
gene id: 882083:SACMADRAFT_RS02755
uniprot id: H5X4C1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882083:SACMADRAFT RS16350
gene id: 882083:SACMADRAFT_RS16350
uniprot id: H5XAQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

882083:SACMADRAFT RS14125
gene id: 882083:SACMADRAFT_RS14125
uniprot id: H5X4P3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS15045
gene id: 882083:SACMADRAFT_RS15045
uniprot id: H5X7L4
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

882083:SACMADRAFT RS21505
gene id: 882083:SACMADRAFT_RS21505
uniprot id: H5X9U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS05115
gene id: 882083:SACMADRAFT_RS05115
uniprot id: H5XBA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

882083:SACMADRAFT RS14965
gene id: 882083:SACMADRAFT_RS14965
uniprot id: H5X6R7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

882083:SACMADRAFT RS06185
gene id: 882083:SACMADRAFT_RS06185
uniprot id: H5WYF4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS06150
gene id: 882083:SACMADRAFT_RS06150
uniprot id: H5WYE7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

882083:SACMADRAFT RS03155
gene id: 882083:SACMADRAFT_RS03155
uniprot id: H5X5C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

882083:SACMADRAFT RS16075
gene id: 882083:SACMADRAFT_RS16075
uniprot id: H5X9R6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

882083:SACMADRAFT RS04685
gene id: 882083:SACMADRAFT_RS04685
uniprot id: H5XA84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS18370
gene id: 882083:SACMADRAFT_RS18370
uniprot id: H5X0V3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS14785
gene id: 882083:SACMADRAFT_RS14785
uniprot id: H5X6N2
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS27990
gene id: 882083:SACMADRAFT_RS27990
uniprot id: H5XC28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

882083:SACMADRAFT RS15190
gene id: 882083:SACMADRAFT_RS15190
uniprot id: H5X7P4
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

882083:SACMADRAFT RS09500
gene id: 882083:SACMADRAFT_RS09500
uniprot id: H5X7I8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

882083:SACMADRAFT RS11590
gene id: 882083:SACMADRAFT_RS11590
uniprot id: H5WXL7
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

882083:SACMADRAFT RS26255
gene id: 882083:SACMADRAFT_RS26255
uniprot id: H5X733
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS15650
gene id: 882083:SACMADRAFT_RS15650
uniprot id: H5X8Q2
names: Similarity
messages: Belongs to the thioredoxin family.

882083:SACMADRAFT RS13380
gene id: 882083:SACMADRAFT_RS13380
uniprot id: H5X2N3
names: Similarity
messages: Belongs to the universal stress protein A family.

882083:SACMADRAFT RS03185
gene id: 882083:SACMADRAFT_RS03185
uniprot id: H5X5D5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

882083:SACMADRAFT RS15690
gene id: 882083:SACMADRAFT_RS15690
uniprot id: H5X8Q9
names: Similarity
messages: Belongs to the UPF0098 family.

882083:SACMADRAFT RS01595
gene id: 882083:SACMADRAFT_RS01595
uniprot id: H5X1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

882083:SACMADRAFT RS04540
gene id: 882083:SACMADRAFT_RS04540
uniprot id: H5X9B8
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

882083:SACMADRAFT RS06280
gene id: 882083:SACMADRAFT_RS06280
uniprot id: H5WYH1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

882083:SACMADRAFT RS10355
gene id: 882083:SACMADRAFT_RS10355
uniprot id: H5XAE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

882083:SACMADRAFT RS04170
gene id: 882083:SACMADRAFT_RS04170
uniprot id: H5X8B4
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

882083:SACMADRAFT RS01145
gene id: 882083:SACMADRAFT_RS01145
uniprot id: H5X083
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS08480
gene id: 882083:SACMADRAFT_RS08480
uniprot id: H5X4K2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882083:SACMADRAFT RS01935
gene id: 882083:SACMADRAFT_RS01935
uniprot id: H5X2A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

882083:SACMADRAFT RS11655
gene id: 882083:SACMADRAFT_RS11655
uniprot id: H5WXN1
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

882083:SACMADRAFT RS05320
gene id: 882083:SACMADRAFT_RS05320
uniprot id: H5WW91
names: Similarity
messages: Belongs to the TPP enzyme family.

882083:SACMADRAFT RS25035
gene id: 882083:SACMADRAFT_RS25035
uniprot id: H5X408
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS11550
gene id: 882083:SACMADRAFT_RS11550
uniprot id: H5WXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

882083:SACMADRAFT RS00130
gene id: 882083:SACMADRAFT_RS00130
uniprot id: H5WX69
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

882083:SACMADRAFT RS17130
gene id: 882083:SACMADRAFT_RS17130
uniprot id: H5WWU6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

882083:SACMADRAFT RS00905
gene id: 882083:SACMADRAFT_RS00905
uniprot id: H5WZ95
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS07080
gene id: 882083:SACMADRAFT_RS07080
uniprot id: H5X0J7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

882083:SACMADRAFT RS03690
gene id: 882083:SACMADRAFT_RS03690
uniprot id: H5X790
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

882083:SACMADRAFT RS13290
gene id: 882083:SACMADRAFT_RS13290
uniprot id: H5X2L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS08660
gene id: 882083:SACMADRAFT_RS08660
uniprot id: H5X5G9
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclic amide hydrolase (CyAH) family.
messages: Homotetramer.
messages: Inhibited by cyanuric acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for the hydrolysis of barbituric acid (2,4,6-trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid.
messages: The monomer structure is formed from three repeating units (RUs) that share the same structure as one another. The monomer and the active site possess nearly threefold rotational symmetry, to the extent that the active site possesses three potential Ser-Lys catalytic dyads, but one of the 3 active site surfaces varies in composition suggesting it is involved in confering substrate specificity.

882083:SACMADRAFT RS12965
gene id: 882083:SACMADRAFT_RS12965
uniprot id: H5X1M8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS13755
gene id: 882083:SACMADRAFT_RS13755
uniprot id: H5X3N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS16180
gene id: 882083:SACMADRAFT_RS16180
uniprot id: H5XAM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

882083:SACMADRAFT RS19885
gene id: 882083:SACMADRAFT_RS19885
uniprot id: H5X4Y0
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

882083:SACMADRAFT RS01865
gene id: 882083:SACMADRAFT_RS01865
uniprot id: H5X293
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

882083:SACMADRAFT RS06685
gene id: 882083:SACMADRAFT_RS06685
uniprot id: H5WZI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

882083:SACMADRAFT RS10570
gene id: 882083:SACMADRAFT_RS10570
uniprot id: H5XAI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

882083:SACMADRAFT RS24345
gene id: 882083:SACMADRAFT_RS24345
uniprot id: H5X215
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

882083:SACMADRAFT RS17920
gene id: 882083:SACMADRAFT_RS17920
uniprot id: H5WZS7
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS03540
gene id: 882083:SACMADRAFT_RS03540
uniprot id: H5X6D3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

882083:SACMADRAFT RS22825
gene id: 882083:SACMADRAFT_RS22825
uniprot id: H5WX11
names: Caution
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

882083:SACMADRAFT RS22960
gene id: 882083:SACMADRAFT_RS22960
uniprot id: H5WXZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS10515
gene id: 882083:SACMADRAFT_RS10515
uniprot id: H5XAH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

882083:SACMADRAFT RS08325
gene id: 882083:SACMADRAFT_RS08325
uniprot id: H5X4H2
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

882083:SACMADRAFT RS17495
gene id: 882083:SACMADRAFT_RS17495
uniprot id: H5WXW9
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

882083:SACMADRAFT RS20255
gene id: 882083:SACMADRAFT_RS20255
uniprot id: H5X5X5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

882083:SACMADRAFT RS08935
gene id: 882083:SACMADRAFT_RS08935
uniprot id: H5X6E8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS07950
gene id: 882083:SACMADRAFT_RS07950
uniprot id: H5X3G7
names: Similarity
messages: Belongs to the peptidase M1 family.

882083:SACMADRAFT RS06430
gene id: 882083:SACMADRAFT_RS06430
uniprot id: H5WZD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

882083:SACMADRAFT RS09480
gene id: 882083:SACMADRAFT_RS09480
uniprot id: H5X7I4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882083:SACMADRAFT RS04115
gene id: 882083:SACMADRAFT_RS04115
uniprot id: H5X8A7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882083:SACMADRAFT RS27670
gene id: 882083:SACMADRAFT_RS27670
uniprot id: H5XB39
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS19150
gene id: 882083:SACMADRAFT_RS19150
uniprot id: H5X2X0
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

882083:SACMADRAFT RS18950
gene id: 882083:SACMADRAFT_RS18950
uniprot id: H5X2T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

882083:SACMADRAFT RS16610
gene id: 882083:SACMADRAFT_RS16610
uniprot id: H5XBN9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS08980
gene id: 882083:SACMADRAFT_RS08980
uniprot id: H5X6F7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

882083:SACMADRAFT RS06275
gene id: 882083:SACMADRAFT_RS06275
uniprot id: H5WYH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

882083:SACMADRAFT RS15785
gene id: 882083:SACMADRAFT_RS15785
uniprot id: H5X9K9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS07595
gene id: 882083:SACMADRAFT_RS07595
uniprot id: H5X2G4
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

882083:SACMADRAFT RS06080
gene id: 882083:SACMADRAFT_RS06080
uniprot id: H5WYD4
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

882083:SACMADRAFT RS08415
gene id: 882083:SACMADRAFT_RS08415
uniprot id: H5X4I8
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

882083:SACMADRAFT RS14635
gene id: 882083:SACMADRAFT_RS14635
uniprot id: H5X5S5
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS18140
gene id: 882083:SACMADRAFT_RS18140
uniprot id: H5WZX0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

882083:SACMADRAFT RS11200
gene id: 882083:SACMADRAFT_RS11200
uniprot id: H5WWI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

882083:SACMADRAFT RS01825
gene id: 882083:SACMADRAFT_RS01825
uniprot id: H5X285
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

882083:SACMADRAFT RS03440
gene id: 882083:SACMADRAFT_RS03440
uniprot id: H5X6B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

882083:SACMADRAFT RS27725
gene id: 882083:SACMADRAFT_RS27725
uniprot id: H5XB48
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

882083:SACMADRAFT RS15970
gene id: 882083:SACMADRAFT_RS15970
uniprot id: H5X9P7
names: Similarity
messages: Belongs to the lycopene cyclase family.

882083:SACMADRAFT RS08060
gene id: 882083:SACMADRAFT_RS08060
uniprot id: H5X3I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

882083:SACMADRAFT RS12150
gene id: 882083:SACMADRAFT_RS12150
uniprot id: H5WZJ9
names: Subcellular Location Annotation
messages: Cytoplasm

882083:SACMADRAFT RS19960
gene id: 882083:SACMADRAFT_RS19960
uniprot id: H5X4Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

882083:SACMADRAFT RS17105
gene id: 882083:SACMADRAFT_RS17105
uniprot id: H5WWU1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

882083:SACMADRAFT RS20120
gene id: 882083:SACMADRAFT_RS20120
uniprot id: H5X5V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

882083:SACMADRAFT RS00735
gene id: 882083:SACMADRAFT_RS00735
uniprot id: H5WZ63
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

882083:SACMADRAFT RS13120
gene id: 882083:SACMADRAFT_RS13120
uniprot id: H5X1Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

882083:SACMADRAFT RS03575
gene id: 882083:SACMADRAFT_RS03575
uniprot id: H5X767
names: Similarity
messages: Belongs to the EccD/Snm4 family.

882083:SACMADRAFT RS10300
gene id: 882083:SACMADRAFT_RS10300
uniprot id: H5X9J9
names: Similarity
messages: Belongs to the CapA family.

882083:SACMADRAFT RS06000
gene id: 882083:SACMADRAFT_RS06000
uniprot id: H5WXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

882083:SACMADRAFT RS03680
gene id: 882083:SACMADRAFT_RS03680
uniprot id: H5X788
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

882083:SACMADRAFT RS27820
gene id: 882083:SACMADRAFT_RS27820
uniprot id: H5XB67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS25545
gene id: 882083:SACMADRAFT_RS25545
uniprot id: H5X548
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

882083:SACMADRAFT RS05400
gene id: 882083:SACMADRAFT_RS05400
uniprot id: H5WWA7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

882083:SACMADRAFT RS17075
gene id: 882083:SACMADRAFT_RS17075
uniprot id: H5WWT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

882083:SACMADRAFT RS07795
gene id: 882083:SACMADRAFT_RS07795
uniprot id: H5X2K4
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS09955
gene id: 882083:SACMADRAFT_RS09955
uniprot id: H5X9D1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS07320
gene id: 882083:SACMADRAFT_RS07320
uniprot id: H5X1I0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

882083:SACMADRAFT RS17490
gene id: 882083:SACMADRAFT_RS17490
uniprot id: H5WXW8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS19765
gene id: 882083:SACMADRAFT_RS19765
uniprot id: H5X4V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

882083:SACMADRAFT RS14835
gene id: 882083:SACMADRAFT_RS14835
uniprot id: H5X6P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

882083:SACMADRAFT RS04985
gene id: 882083:SACMADRAFT_RS04985
uniprot id: H5XB75
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

882083:SACMADRAFT RS02915
gene id: 882083:SACMADRAFT_RS02915
uniprot id: H5X585
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

882083:SACMADRAFT RS11330
gene id: 882083:SACMADRAFT_RS11330
uniprot id: H5WWL2
names: Similarity
messages: Belongs to the UPF0166 family.

882083:SACMADRAFT RS22200
gene id: 882083:SACMADRAFT_RS22200
uniprot id: H5XBT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

882083:SACMADRAFT RS05170
gene id: 882083:SACMADRAFT_RS05170
uniprot id: H5XBA9
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

882083:SACMADRAFT RS17680
gene id: 882083:SACMADRAFT_RS17680
uniprot id: H5WYU5
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS09600
gene id: 882083:SACMADRAFT_RS09600
uniprot id: H5X8D0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

882083:SACMADRAFT RS22290
gene id: 882083:SACMADRAFT_RS22290
uniprot id: H5XBV0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

882083:SACMADRAFT RS08015
gene id: 882083:SACMADRAFT_RS08015
uniprot id: H5X3H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

882083:SACMADRAFT RS08795
gene id: 882083:SACMADRAFT_RS08795
uniprot id: H5X5J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS09705
gene id: 882083:SACMADRAFT_RS09705
uniprot id: H5X8F1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

882083:SACMADRAFT RS00640
gene id: 882083:SACMADRAFT_RS00640
uniprot id: H5WYB3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

882083:SACMADRAFT RS27310
gene id: 882083:SACMADRAFT_RS27310
uniprot id: H5XA35
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882083:SACMADRAFT RS03275
gene id: 882083:SACMADRAFT_RS03275
uniprot id: H5X679
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

882083:SACMADRAFT RS11895
gene id: 882083:SACMADRAFT_RS11895
uniprot id: H5WYL7
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS04135
gene id: 882083:SACMADRAFT_RS04135
uniprot id: H5X8B0
names: Similarity
messages: Belongs to the UPRTase family.

882083:SACMADRAFT RS13680
gene id: 882083:SACMADRAFT_RS13680
uniprot id: H5X3L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS15675
gene id: 882083:SACMADRAFT_RS15675
uniprot id: H5X8Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

882083:SACMADRAFT RS25540
gene id: 882083:SACMADRAFT_RS25540
uniprot id: H5X547
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

882083:SACMADRAFT RS22910
gene id: 882083:SACMADRAFT_RS22910
uniprot id: H5WXY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

882083:SACMADRAFT RS10615
gene id: 882083:SACMADRAFT_RS10615
uniprot id: H5XAJ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

882083:SACMADRAFT RS15995
gene id: 882083:SACMADRAFT_RS15995
uniprot id: H5X9Q2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

882083:SACMADRAFT RS12200
gene id: 882083:SACMADRAFT_RS12200
uniprot id: H5WZK9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS27600
gene id: 882083:SACMADRAFT_RS27600
uniprot id: H5XB25
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS01255
gene id: 882083:SACMADRAFT_RS01255
uniprot id: H5X0A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

882083:SACMADRAFT RS22105
gene id: 882083:SACMADRAFT_RS22105
uniprot id: H5XAZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

882083:SACMADRAFT RS07120
gene id: 882083:SACMADRAFT_RS07120
uniprot id: H5X0K5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

882083:SACMADRAFT RS28120
gene id: 882083:SACMADRAFT_RS28120
uniprot id: H5XC55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

882083:SACMADRAFT RS14040
gene id: 882083:SACMADRAFT_RS14040
uniprot id: H5X4M6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS25565
gene id: 882083:SACMADRAFT_RS25565
uniprot id: H5X552
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS09855
gene id: 882083:SACMADRAFT_RS09855
uniprot id: H5X8H9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

882083:SACMADRAFT RS09300
gene id: 882083:SACMADRAFT_RS09300
uniprot id: H5X7E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS14405
gene id: 882083:SACMADRAFT_RS14405
uniprot id: H5X5M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Vgb family.
messages: Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.
messages: Monomer.

882083:SACMADRAFT RS12630
gene id: 882083:SACMADRAFT_RS12630
uniprot id: H5X0M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

882083:SACMADRAFT RS02600
gene id: 882083:SACMADRAFT_RS02600
uniprot id: H5X490
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

882083:SACMADRAFT RS00330
gene id: 882083:SACMADRAFT_RS00330
uniprot id: H5WXA9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

882083:SACMADRAFT RS28265
gene id: 882083:SACMADRAFT_RS28265
uniprot id: H5WX33
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS19770
gene id: 882083:SACMADRAFT_RS19770
uniprot id: H5X4V6
names: Similarity
messages: Belongs to the peptidase S33 family.

882083:SACMADRAFT RS19110
gene id: 882083:SACMADRAFT_RS19110
uniprot id: H5X2W2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

882083:SACMADRAFT RS08845
gene id: 882083:SACMADRAFT_RS08845
uniprot id: H5X5K6
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

882083:SACMADRAFT RS12085
gene id: 882083:SACMADRAFT_RS12085
uniprot id: H5WYQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS22665
gene id: 882083:SACMADRAFT_RS22665
uniprot id: H5WWY2
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

882083:SACMADRAFT RS25255
gene id: 882083:SACMADRAFT_RS25255
uniprot id: H5X450
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

882083:SACMADRAFT RS16740
gene id: 882083:SACMADRAFT_RS16740
uniprot id: H5XBR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

882083:SACMADRAFT RS04010
gene id: 882083:SACMADRAFT_RS04010
uniprot id: H5X885
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

882083:SACMADRAFT RS27030
gene id: 882083:SACMADRAFT_RS27030
uniprot id: H5X937
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

882083:SACMADRAFT RS22565
gene id: 882083:SACMADRAFT_RS22565
uniprot id: H5WWW4
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

882083:SACMADRAFT RS23545
gene id: 882083:SACMADRAFT_RS23545
uniprot id: H5WZ50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

882083:SACMADRAFT RS20160
gene id: 882083:SACMADRAFT_RS20160
uniprot id: H5X5W0
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

882083:SACMADRAFT RS23965
gene id: 882083:SACMADRAFT_RS23965
uniprot id: H5X113
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

882083:SACMADRAFT RS22730
gene id: 882083:SACMADRAFT_RS22730
uniprot id: H5WWZ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS25520
gene id: 882083:SACMADRAFT_RS25520
uniprot id: H5X542
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS25265
gene id: 882083:SACMADRAFT_RS25265
uniprot id: H5X452
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

882083:SACMADRAFT RS01010
gene id: 882083:SACMADRAFT_RS01010
uniprot id: H5WZB4
names: Similarity
messages: Belongs to the asparaginase 1 family.

882083:SACMADRAFT RS15245
gene id: 882083:SACMADRAFT_RS15245
uniprot id: H5X7Q3
names: Similarity
messages: Belongs to the peptidase S9C family.

882083:SACMADRAFT RS09255
gene id: 882083:SACMADRAFT_RS09255
uniprot id: H5X7D9
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS01180
gene id: 882083:SACMADRAFT_RS01180
uniprot id: H5X090
names: Similarity
messages: Belongs to the EccE family.

882083:SACMADRAFT RS03255
gene id: 882083:SACMADRAFT_RS03255
uniprot id: H5X675
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

882083:SACMADRAFT RS10110
gene id: 882083:SACMADRAFT_RS10110
uniprot id: H5X9G1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS19420
gene id: 882083:SACMADRAFT_RS19420
uniprot id: H5X3U9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

882083:SACMADRAFT RS24975
gene id: 882083:SACMADRAFT_RS24975
uniprot id: H5X3Z7
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS03910
gene id: 882083:SACMADRAFT_RS03910
uniprot id: H5X865
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

882083:SACMADRAFT RS09530
gene id: 882083:SACMADRAFT_RS09530
uniprot id: H5X7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882083:SACMADRAFT RS22260
gene id: 882083:SACMADRAFT_RS22260
uniprot id: H5XBU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS11890
gene id: 882083:SACMADRAFT_RS11890
uniprot id: H5WYL6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS13795
gene id: 882083:SACMADRAFT_RS13795
uniprot id: H5X3P2
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS25290
gene id: 882083:SACMADRAFT_RS25290
uniprot id: H5X457
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

882083:SACMADRAFT RS00005
gene id: 882083:SACMADRAFT_RS00005
uniprot id: H5WX49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

882083:SACMADRAFT RS21050
gene id: 882083:SACMADRAFT_RS21050
uniprot id: H5X7Y8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882083:SACMADRAFT RS03590
gene id: 882083:SACMADRAFT_RS03590
uniprot id: H5X770
names: Similarity
messages: Belongs to the WXG100 family.

882083:SACMADRAFT RS06865
gene id: 882083:SACMADRAFT_RS06865
uniprot id: H5X0F4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

882083:SACMADRAFT RS25555
gene id: 882083:SACMADRAFT_RS25555
uniprot id: H5X550
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS23580
gene id: 882083:SACMADRAFT_RS23580
uniprot id: H5WZZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

882083:SACMADRAFT RS27880
gene id: 882083:SACMADRAFT_RS27880
uniprot id: H5XC05
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

882083:SACMADRAFT RS05855
gene id: 882083:SACMADRAFT_RS05855
uniprot id: H5WXF2
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

882083:SACMADRAFT RS05545
gene id: 882083:SACMADRAFT_RS05545
uniprot id: H5WWD4
names: Similarity
messages: Belongs to the HypD family.

882083:SACMADRAFT RS14975
gene id: 882083:SACMADRAFT_RS14975
uniprot id: H5X6R9
names: Similarity
messages: Belongs to the archease family.

882083:SACMADRAFT RS16800
gene id: 882083:SACMADRAFT_RS16800
uniprot id: H5WWN6
names: Similarity
messages: Belongs to the HsdR family.

882083:SACMADRAFT RS10470
gene id: 882083:SACMADRAFT_RS10470
uniprot id: H5XAG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

882083:SACMADRAFT RS21455
gene id: 882083:SACMADRAFT_RS21455
uniprot id: H5X9T4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

882083:SACMADRAFT RS07930
gene id: 882083:SACMADRAFT_RS07930
uniprot id: H5X3G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

882083:SACMADRAFT RS04180
gene id: 882083:SACMADRAFT_RS04180
uniprot id: H5X8B6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

882083:SACMADRAFT RS26980
gene id: 882083:SACMADRAFT_RS26980
uniprot id: H5X927
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.

882083:SACMADRAFT RS22120
gene id: 882083:SACMADRAFT_RS22120
uniprot id: H5XAZ3
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS19030
gene id: 882083:SACMADRAFT_RS19030
uniprot id: H5X2U7
names: Similarity
messages: Belongs to the peptidase C40 family.

882083:SACMADRAFT RS17210
gene id: 882083:SACMADRAFT_RS17210
uniprot id: H5WXR6
names: Similarity
messages: Belongs to the peptidase S9C family.

882083:SACMADRAFT RS27140
gene id: 882083:SACMADRAFT_RS27140
uniprot id: H5XA02
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS08395
gene id: 882083:SACMADRAFT_RS08395
uniprot id: H5X4I6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

882083:SACMADRAFT RS19710
gene id: 882083:SACMADRAFT_RS19710
uniprot id: H5X4U5
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

882083:SACMADRAFT RS16750
gene id: 882083:SACMADRAFT_RS16750
uniprot id: H5XBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

882083:SACMADRAFT RS03395
gene id: 882083:SACMADRAFT_RS03395
uniprot id: H5X6A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

882083:SACMADRAFT RS04990
gene id: 882083:SACMADRAFT_RS04990
uniprot id: H5XB76
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS05860
gene id: 882083:SACMADRAFT_RS05860
uniprot id: H5WXF3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

882083:SACMADRAFT RS03740
gene id: 882083:SACMADRAFT_RS03740
uniprot id: H5X7D1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS05985
gene id: 882083:SACMADRAFT_RS05985
uniprot id: H5WXH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

882083:SACMADRAFT RS03445
gene id: 882083:SACMADRAFT_RS03445
uniprot id: H5X6B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

882083:SACMADRAFT RS25345
gene id: 882083:SACMADRAFT_RS25345
uniprot id: H5X509
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS17995
gene id: 882083:SACMADRAFT_RS17995
uniprot id: H5WZU1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

882083:SACMADRAFT RS15505
gene id: 882083:SACMADRAFT_RS15505
uniprot id: H5X8M5
names: Similarity
messages: Belongs to the AHA1 family.

882083:SACMADRAFT RS22380
gene id: 882083:SACMADRAFT_RS22380
uniprot id: H5XBW8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS19740
gene id: 882083:SACMADRAFT_RS19740
uniprot id: H5X4V0
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

882083:SACMADRAFT RS08930
gene id: 882083:SACMADRAFT_RS08930
uniprot id: H5X6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

882083:SACMADRAFT RS21645
gene id: 882083:SACMADRAFT_RS21645
uniprot id: H5X9X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

882083:SACMADRAFT RS23515
gene id: 882083:SACMADRAFT_RS23515
uniprot id: H5WZ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

882083:SACMADRAFT RS11325
gene id: 882083:SACMADRAFT_RS11325
uniprot id: H5WWL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

882083:SACMADRAFT RS24445
gene id: 882083:SACMADRAFT_RS24445
uniprot id: H5X235
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

882083:SACMADRAFT RS17085
gene id: 882083:SACMADRAFT_RS17085
uniprot id: H5WWT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

882083:SACMADRAFT RS13665
gene id: 882083:SACMADRAFT_RS13665
uniprot id: H5X3L6
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

882083:SACMADRAFT RS24245
gene id: 882083:SACMADRAFT_RS24245
uniprot id: H5X165
names: Subcellular Location Annotation
messages: Periplasm

882083:SACMADRAFT RS22510
gene id: 882083:SACMADRAFT_RS22510
uniprot id: H5XBZ4
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

882083:SACMADRAFT RS22235
gene id: 882083:SACMADRAFT_RS22235
uniprot id: H5XBT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

882083:SACMADRAFT RS03645
gene id: 882083:SACMADRAFT_RS03645
uniprot id: H5X781
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

882083:SACMADRAFT RS07100
gene id: 882083:SACMADRAFT_RS07100
uniprot id: H5X0K1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

882083:SACMADRAFT RS17855
gene id: 882083:SACMADRAFT_RS17855
uniprot id: H5WYX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

882083:SACMADRAFT RS04040
gene id: 882083:SACMADRAFT_RS04040
uniprot id: H5X891
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

882083:SACMADRAFT RS02910
gene id: 882083:SACMADRAFT_RS02910
uniprot id: H5X584
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

882083:SACMADRAFT RS03435
gene id: 882083:SACMADRAFT_RS03435
uniprot id: H5X6B1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

882083:SACMADRAFT RS19875
gene id: 882083:SACMADRAFT_RS19875
uniprot id: H5X4X8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

882083:SACMADRAFT RS08800
gene id: 882083:SACMADRAFT_RS08800
uniprot id: H5X5J7
names: Similarity
messages: Belongs to the CdaR family.

882083:SACMADRAFT RS09865
gene id: 882083:SACMADRAFT_RS09865
uniprot id: H5X8I1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS16030
gene id: 882083:SACMADRAFT_RS16030
uniprot id: H5X9Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS04665
gene id: 882083:SACMADRAFT_RS04665
uniprot id: H5X852
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS27360
gene id: 882083:SACMADRAFT_RS27360
uniprot id: H5XA45
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS19665
gene id: 882083:SACMADRAFT_RS19665
uniprot id: H5X4T6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS18190
gene id: 882083:SACMADRAFT_RS18190
uniprot id: H5WZY0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS16135
gene id: 882083:SACMADRAFT_RS16135
uniprot id: H5XAL4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

882083:SACMADRAFT RS16880
gene id: 882083:SACMADRAFT_RS16880
uniprot id: H5WWQ1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

882083:SACMADRAFT RS13415
gene id: 882083:SACMADRAFT_RS13415
uniprot id: H5X2P0
names: Similarity
messages: Belongs to the universal stress protein A family.

882083:SACMADRAFT RS04565
gene id: 882083:SACMADRAFT_RS04565
uniprot id: H5X9C3
names: Similarity
messages: Belongs to the LOG family.

882083:SACMADRAFT RS19615
gene id: 882083:SACMADRAFT_RS19615
uniprot id: H5X3Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS05600
gene id: 882083:SACMADRAFT_RS05600
uniprot id: H5WWE3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

882083:SACMADRAFT RS03565
gene id: 882083:SACMADRAFT_RS03565
uniprot id: H5X765
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

882083:SACMADRAFT RS03450
gene id: 882083:SACMADRAFT_RS03450
uniprot id: H5X6B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

882083:SACMADRAFT RS20050
gene id: 882083:SACMADRAFT_RS20050
uniprot id: H5X5T8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS15835
gene id: 882083:SACMADRAFT_RS15835
uniprot id: H5X9L9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS16290
gene id: 882083:SACMADRAFT_RS16290
uniprot id: H5XAP5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

882083:SACMADRAFT RS08720
gene id: 882083:SACMADRAFT_RS08720
uniprot id: H5X5I1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882083:SACMADRAFT RS13425
gene id: 882083:SACMADRAFT_RS13425
uniprot id: H5X2P2
names: Similarity
messages: Belongs to the universal stress protein A family.

882083:SACMADRAFT RS06195
gene id: 882083:SACMADRAFT_RS06195
uniprot id: H5WYF6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

882083:SACMADRAFT RS06790
gene id: 882083:SACMADRAFT_RS06790
uniprot id: H5X0E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

882083:SACMADRAFT RS13825
gene id: 882083:SACMADRAFT_RS13825
uniprot id: H5X3P7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

882083:SACMADRAFT RS23215
gene id: 882083:SACMADRAFT_RS23215
uniprot id: H5WY53
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

882083:SACMADRAFT RS21785
gene id: 882083:SACMADRAFT_RS21785
uniprot id: H5X9Z8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

882083:SACMADRAFT RS11090
gene id: 882083:SACMADRAFT_RS11090
uniprot id: H5WWG4
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS06740
gene id: 882083:SACMADRAFT_RS06740
uniprot id: H5WZJ3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

882083:SACMADRAFT RS06245
gene id: 882083:SACMADRAFT_RS06245
uniprot id: H5WYG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

882083:SACMADRAFT RS10400
gene id: 882083:SACMADRAFT_RS10400
uniprot id: H5XAF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

882083:SACMADRAFT RS09310
gene id: 882083:SACMADRAFT_RS09310
uniprot id: H5X7E8
names: Similarity
messages: Belongs to the TPP enzyme family.

882083:SACMADRAFT RS24340
gene id: 882083:SACMADRAFT_RS24340
uniprot id: H5X214
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS04235
gene id: 882083:SACMADRAFT_RS04235
uniprot id: H5X8C8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

882083:SACMADRAFT RS20435
gene id: 882083:SACMADRAFT_RS20435
uniprot id: H5X6T8
names: Similarity
messages: Belongs to the GSP E family.

882083:SACMADRAFT RS16575
gene id: 882083:SACMADRAFT_RS16575
uniprot id: H5XBN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS09680
gene id: 882083:SACMADRAFT_RS09680
uniprot id: H5X8E6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS09515
gene id: 882083:SACMADRAFT_RS09515
uniprot id: H5X7J1
names: Similarity
messages: Belongs to the transketolase family.

882083:SACMADRAFT RS10770
gene id: 882083:SACMADRAFT_RS10770
uniprot id: H5XBF2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882083:SACMADRAFT RS04680
gene id: 882083:SACMADRAFT_RS04680
uniprot id: H5XA83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS13520
gene id: 882083:SACMADRAFT_RS13520
uniprot id: H5X2R1
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS13060
gene id: 882083:SACMADRAFT_RS13060
uniprot id: H5X1P7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882083:SACMADRAFT RS06715
gene id: 882083:SACMADRAFT_RS06715
uniprot id: H5WZI8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

882083:SACMADRAFT RS26455
gene id: 882083:SACMADRAFT_RS26455
uniprot id: H5X802
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

882083:SACMADRAFT RS06155
gene id: 882083:SACMADRAFT_RS06155
uniprot id: H5WYE8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

882083:SACMADRAFT RS29735
gene id: 882083:SACMADRAFT_RS29735
uniprot id: H5X647
names: Similarity
messages: Belongs to the GSP E family.

882083:SACMADRAFT RS10335
gene id: 882083:SACMADRAFT_RS10335
uniprot id: H5XAE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

882083:SACMADRAFT RS06750
gene id: 882083:SACMADRAFT_RS06750
uniprot id: H5WZJ5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS08160
gene id: 882083:SACMADRAFT_RS08160
uniprot id: H5X4D9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

882083:SACMADRAFT RS02065
gene id: 882083:SACMADRAFT_RS02065
uniprot id: H5X2D1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

882083:SACMADRAFT RS16635
gene id: 882083:SACMADRAFT_RS16635
uniprot id: H5XBP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

882083:SACMADRAFT RS01405
gene id: 882083:SACMADRAFT_RS01405
uniprot id: H5X172
names: Similarity
messages: Belongs to the EspG family.

882083:SACMADRAFT RS20085
gene id: 882083:SACMADRAFT_RS20085
uniprot id: H5X5U5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS07210
gene id: 882083:SACMADRAFT_RS07210
uniprot id: H5X1F7
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

882083:SACMADRAFT RS22285
gene id: 882083:SACMADRAFT_RS22285
uniprot id: H5XBU9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

882083:SACMADRAFT RS14420
gene id: 882083:SACMADRAFT_RS14420
uniprot id: H5X5N0
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS01870
gene id: 882083:SACMADRAFT_RS01870
uniprot id: H5X294
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS06625
gene id: 882083:SACMADRAFT_RS06625
uniprot id: H5WZH0
names: Similarity
messages: Belongs to the P(II) protein family.

882083:SACMADRAFT RS20065
gene id: 882083:SACMADRAFT_RS20065
uniprot id: H5X5U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS16395
gene id: 882083:SACMADRAFT_RS16395
uniprot id: H5XAR6
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

882083:SACMADRAFT RS11185
gene id: 882083:SACMADRAFT_RS11185
uniprot id: H5WWI3
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS03245
gene id: 882083:SACMADRAFT_RS03245
uniprot id: H5X673
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

882083:SACMADRAFT RS16915
gene id: 882083:SACMADRAFT_RS16915
uniprot id: H5WWQ8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS18530
gene id: 882083:SACMADRAFT_RS18530
uniprot id: H5X0Y6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

882083:SACMADRAFT RS04610
gene id: 882083:SACMADRAFT_RS04610
uniprot id: H5XA69
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882083:SACMADRAFT RS07065
gene id: 882083:SACMADRAFT_RS07065
uniprot id: H5X0J4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS15300
gene id: 882083:SACMADRAFT_RS15300
uniprot id: H5X7R2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

882083:SACMADRAFT RS08190
gene id: 882083:SACMADRAFT_RS08190
uniprot id: H5X4E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

882083:SACMADRAFT RS22425
gene id: 882083:SACMADRAFT_RS22425
uniprot id: H5XBX7
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

882083:SACMADRAFT RS22145
gene id: 882083:SACMADRAFT_RS22145
uniprot id: H5XAZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

882083:SACMADRAFT RS24565
gene id: 882083:SACMADRAFT_RS24565
uniprot id: H5X257
names: Similarity
messages: Belongs to the GSP E family.

882083:SACMADRAFT RS00985
gene id: 882083:SACMADRAFT_RS00985
uniprot id: H5WZA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

882083:SACMADRAFT RS08745
gene id: 882083:SACMADRAFT_RS08745
uniprot id: H5X5I6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS13270
gene id: 882083:SACMADRAFT_RS13270
uniprot id: H5X2L3
names: Similarity
messages: Belongs to the ArsC family.

882083:SACMADRAFT RS16965
gene id: 882083:SACMADRAFT_RS16965
uniprot id: H5WWR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

882083:SACMADRAFT RS02235
gene id: 882083:SACMADRAFT_RS02235
uniprot id: H5X391
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS01075
gene id: 882083:SACMADRAFT_RS01075
uniprot id: H5X069
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

882083:SACMADRAFT RS24910
gene id: 882083:SACMADRAFT_RS24910
uniprot id: H5X355
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

882083:SACMADRAFT RS24410
gene id: 882083:SACMADRAFT_RS24410
uniprot id: H5X228
names: Similarity
messages: Belongs to the EspG family.

882083:SACMADRAFT RS07085
gene id: 882083:SACMADRAFT_RS07085
uniprot id: H5X0J8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

882083:SACMADRAFT RS16365
gene id: 882083:SACMADRAFT_RS16365
uniprot id: H5XAR0
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

882083:SACMADRAFT RS23810
gene id: 882083:SACMADRAFT_RS23810
uniprot id: H5X044
names: Similarity
names: Subunit
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. SbnA subfamily.
messages: Homodimer.

882083:SACMADRAFT RS08815
gene id: 882083:SACMADRAFT_RS08815
uniprot id: H5X5K0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

882083:SACMADRAFT RS07270
gene id: 882083:SACMADRAFT_RS07270
uniprot id: H5X1G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS10340
gene id: 882083:SACMADRAFT_RS10340
uniprot id: H5XAE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

882083:SACMADRAFT RS03470
gene id: 882083:SACMADRAFT_RS03470
uniprot id: H5X6B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

882083:SACMADRAFT RS18470
gene id: 882083:SACMADRAFT_RS18470
uniprot id: H5X0X3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

882083:SACMADRAFT RS28465
gene id: 882083:SACMADRAFT_RS28465
uniprot id: H5X7F0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882083:SACMADRAFT RS31030
gene id: 882083:SACMADRAFT_RS31030
uniprot id: H5X5X3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

882083:SACMADRAFT RS16355
gene id: 882083:SACMADRAFT_RS16355
uniprot id: H5XAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

882083:SACMADRAFT RS18325
gene id: 882083:SACMADRAFT_RS18325
uniprot id: H5X0U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

882083:SACMADRAFT RS07920
gene id: 882083:SACMADRAFT_RS07920
uniprot id: H5X3G0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

882083:SACMADRAFT RS19795
gene id: 882083:SACMADRAFT_RS19795
uniprot id: H5X4W2
names: Subcellular Location Annotation
messages: Cytoplasm

882083:SACMADRAFT RS14760
gene id: 882083:SACMADRAFT_RS14760
uniprot id: H5X6M7
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

882083:SACMADRAFT RS00020
gene id: 882083:SACMADRAFT_RS00020
uniprot id: H5WX52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

882083:SACMADRAFT RS13585
gene id: 882083:SACMADRAFT_RS13585
uniprot id: H5X2S4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

882083:SACMADRAFT RS18265
gene id: 882083:SACMADRAFT_RS18265
uniprot id: H5X0T2
names: Similarity
messages: Belongs to the peptidase S15 family.

882083:SACMADRAFT RS17465
gene id: 882083:SACMADRAFT_RS17465
uniprot id: H5WXW3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS19220
gene id: 882083:SACMADRAFT_RS19220
uniprot id: H5X2Y2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

882083:SACMADRAFT RS22725
gene id: 882083:SACMADRAFT_RS22725
uniprot id: H5WWZ2
names: Similarity
messages: Belongs to the YciI family.

882083:SACMADRAFT RS08330
gene id: 882083:SACMADRAFT_RS08330
uniprot id: H5X4H3
names: Similarity
messages: Belongs to the barstar family.

882083:SACMADRAFT RS11395
gene id: 882083:SACMADRAFT_RS11395
uniprot id: H5WWM5
names: Similarity
messages: Belongs to the HsdR family.

882083:SACMADRAFT RS08290
gene id: 882083:SACMADRAFT_RS08290
uniprot id: H5X4G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

882083:SACMADRAFT RS04095
gene id: 882083:SACMADRAFT_RS04095
uniprot id: H5X8A3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS18445
gene id: 882083:SACMADRAFT_RS18445
uniprot id: H5X0W8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

882083:SACMADRAFT RS15260
gene id: 882083:SACMADRAFT_RS15260
uniprot id: H5X7Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS22855
gene id: 882083:SACMADRAFT_RS22855
uniprot id: H5WX16
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS27120
gene id: 882083:SACMADRAFT_RS27120
uniprot id: H5X955
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS11390
gene id: 882083:SACMADRAFT_RS11390
uniprot id: H5WWM3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

882083:SACMADRAFT RS15305
gene id: 882083:SACMADRAFT_RS15305
uniprot id: H5X7R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

882083:SACMADRAFT RS16535
gene id: 882083:SACMADRAFT_RS16535
uniprot id: H5XBM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

882083:SACMADRAFT RS26050
gene id: 882083:SACMADRAFT_RS26050
uniprot id: H5X6Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

882083:SACMADRAFT RS22955
gene id: 882083:SACMADRAFT_RS22955
uniprot id: H5WXZ8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

882083:SACMADRAFT RS12005
gene id: 882083:SACMADRAFT_RS12005
uniprot id: H5WYN9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

882083:SACMADRAFT RS05000
gene id: 882083:SACMADRAFT_RS05000
uniprot id: H5XB78
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

882083:SACMADRAFT RS09275
gene id: 882083:SACMADRAFT_RS09275
uniprot id: H5X7E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

882083:SACMADRAFT RS11625
gene id: 882083:SACMADRAFT_RS11625
uniprot id: H5WXM4
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

882083:SACMADRAFT RS03495
gene id: 882083:SACMADRAFT_RS03495
uniprot id: H5X6C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

882083:SACMADRAFT RS03545
gene id: 882083:SACMADRAFT_RS03545
uniprot id: H5X6D4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

882083:SACMADRAFT RS21450
gene id: 882083:SACMADRAFT_RS21450
uniprot id: H5X9T3
names: Similarity
messages: Belongs to the UPF0434 family.

882083:SACMADRAFT RS01800
gene id: 882083:SACMADRAFT_RS01800
uniprot id: H5X280
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS08925
gene id: 882083:SACMADRAFT_RS08925
uniprot id: H5X6E6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

882083:SACMADRAFT RS22450
gene id: 882083:SACMADRAFT_RS22450
uniprot id: H5XBY2
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

882083:SACMADRAFT RS20990
gene id: 882083:SACMADRAFT_RS20990
uniprot id: H5X7X7
names: Similarity
messages: Belongs to the TPP enzyme family.

882083:SACMADRAFT RS02445
gene id: 882083:SACMADRAFT_RS02445
uniprot id: H5X3D5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

882083:SACMADRAFT RS27575
gene id: 882083:SACMADRAFT_RS27575
uniprot id: H5XB20
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS19120
gene id: 882083:SACMADRAFT_RS19120
uniprot id: H5X2W4
names: Similarity
messages: Belongs to the thioredoxin family.

882083:SACMADRAFT RS12685
gene id: 882083:SACMADRAFT_RS12685
uniprot id: H5X0N9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882083:SACMADRAFT RS17605
gene id: 882083:SACMADRAFT_RS17605
uniprot id: H5WYS9
names: Similarity
messages: Belongs to the asparagine synthetase family.

882083:SACMADRAFT RS05315
gene id: 882083:SACMADRAFT_RS05315
uniprot id: H5WW90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS20135
gene id: 882083:SACMADRAFT_RS20135
uniprot id: H5X5V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

882083:SACMADRAFT RS12345
gene id: 882083:SACMADRAFT_RS12345
uniprot id: H5WZN6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS03555
gene id: 882083:SACMADRAFT_RS03555
uniprot id: H5X763
names: Similarity
messages: Belongs to the EccE family.

882083:SACMADRAFT RS01960
gene id: 882083:SACMADRAFT_RS01960
uniprot id: H5X2B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS25605
gene id: 882083:SACMADRAFT_RS25605
uniprot id: H5X560
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS22255
gene id: 882083:SACMADRAFT_RS22255
uniprot id: H5XBU2
names: Similarity
messages: Belongs to the group II decarboxylase family.

882083:SACMADRAFT RS06795
gene id: 882083:SACMADRAFT_RS06795
uniprot id: H5X0E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

882083:SACMADRAFT RS18810
gene id: 882083:SACMADRAFT_RS18810
uniprot id: H5X1X6
names: Similarity
messages: Belongs to the TrpC family.

882083:SACMADRAFT RS09145
gene id: 882083:SACMADRAFT_RS09145
uniprot id: H5X6J1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

882083:SACMADRAFT RS08830
gene id: 882083:SACMADRAFT_RS08830
uniprot id: H5X5K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

882083:SACMADRAFT RS30420
gene id: 882083:SACMADRAFT_RS30420
uniprot id: H5X9N6
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

882083:SACMADRAFT RS24905
gene id: 882083:SACMADRAFT_RS24905
uniprot id: H5X354
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

882083:SACMADRAFT RS13930
gene id: 882083:SACMADRAFT_RS13930
uniprot id: H5X3R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

882083:SACMADRAFT RS22070
gene id: 882083:SACMADRAFT_RS22070
uniprot id: H5XAY3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

882083:SACMADRAFT RS03215
gene id: 882083:SACMADRAFT_RS03215
uniprot id: H5X668
names: Similarity
messages: Belongs to the peptidase S1 family.

882083:SACMADRAFT RS14255
gene id: 882083:SACMADRAFT_RS14255
uniprot id: H5X4R9
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

882083:SACMADRAFT RS21995
gene id: 882083:SACMADRAFT_RS21995
uniprot id: H5XAW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS23995
gene id: 882083:SACMADRAFT_RS23995
uniprot id: H5X118
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882083:SACMADRAFT RS20105
gene id: 882083:SACMADRAFT_RS20105
uniprot id: H5X5U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

882083:SACMADRAFT RS04045
gene id: 882083:SACMADRAFT_RS04045
uniprot id: H5X892
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

882083:SACMADRAFT RS07035
gene id: 882083:SACMADRAFT_RS07035
uniprot id: H5X0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS21380
gene id: 882083:SACMADRAFT_RS21380
uniprot id: H5X8Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

882083:SACMADRAFT RS28255
gene id: 882083:SACMADRAFT_RS28255
uniprot id: H5WX31
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS06510
gene id: 882083:SACMADRAFT_RS06510
uniprot id: H5WZE7
names: Similarity
messages: Belongs to the HIBADH-related family.

882083:SACMADRAFT RS12805
gene id: 882083:SACMADRAFT_RS12805
uniprot id: H5X0R3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

882083:SACMADRAFT RS24615
gene id: 882083:SACMADRAFT_RS24615
uniprot id: H5X267
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS11320
gene id: 882083:SACMADRAFT_RS11320
uniprot id: H5WWL0
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

882083:SACMADRAFT RS17980
gene id: 882083:SACMADRAFT_RS17980
uniprot id: H5WZT8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

882083:SACMADRAFT RS03385
gene id: 882083:SACMADRAFT_RS03385
uniprot id: H5X6A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

882083:SACMADRAFT RS06220
gene id: 882083:SACMADRAFT_RS06220
uniprot id: H5WYG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS21020
gene id: 882083:SACMADRAFT_RS21020
uniprot id: H5X7Y2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

882083:SACMADRAFT RS25665
gene id: 882083:SACMADRAFT_RS25665
uniprot id: H5X605
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

882083:SACMADRAFT RS27370
gene id: 882083:SACMADRAFT_RS27370
uniprot id: H5XA47
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

882083:SACMADRAFT RS20030
gene id: 882083:SACMADRAFT_RS20030
uniprot id: H5X5T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS25920
gene id: 882083:SACMADRAFT_RS25920
uniprot id: H5X645
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS17290
gene id: 882083:SACMADRAFT_RS17290
uniprot id: H5WXT2
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS10710
gene id: 882083:SACMADRAFT_RS10710
uniprot id: H5XBD9
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

882083:SACMADRAFT RS28040
gene id: 882083:SACMADRAFT_RS28040
uniprot id: H5XC38
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS13325
gene id: 882083:SACMADRAFT_RS13325
uniprot id: H5X2M4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

882083:SACMADRAFT RS26825
gene id: 882083:SACMADRAFT_RS26825
uniprot id: H5X8Z6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

882083:SACMADRAFT RS19485
gene id: 882083:SACMADRAFT_RS19485
uniprot id: H5X3W1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882083:SACMADRAFT RS05385
gene id: 882083:SACMADRAFT_RS05385
uniprot id: H5WWA4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882083:SACMADRAFT RS06595
gene id: 882083:SACMADRAFT_RS06595
uniprot id: H5WZG4
names: Similarity
messages: Belongs to the FGGY kinase family.

882083:SACMADRAFT RS18830
gene id: 882083:SACMADRAFT_RS18830
uniprot id: H5X1Y0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS16450
gene id: 882083:SACMADRAFT_RS16450
uniprot id: H5XAS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

882083:SACMADRAFT RS00460
gene id: 882083:SACMADRAFT_RS00460
uniprot id: H5WY76
names: Similarity
messages: Belongs to the universal stress protein A family.

882083:SACMADRAFT RS11400
gene id: 882083:SACMADRAFT_RS11400
uniprot id: H5WWM6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

882083:SACMADRAFT RS09595
gene id: 882083:SACMADRAFT_RS09595
uniprot id: H5X8C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

882083:SACMADRAFT RS08185
gene id: 882083:SACMADRAFT_RS08185
uniprot id: H5X4E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

882083:SACMADRAFT RS27425
gene id: 882083:SACMADRAFT_RS27425
uniprot id: H5XA59
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882083:SACMADRAFT RS16910
gene id: 882083:SACMADRAFT_RS16910
uniprot id: H5WWQ7
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS16430
gene id: 882083:SACMADRAFT_RS16430
uniprot id: H5XAS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

882083:SACMADRAFT RS20130
gene id: 882083:SACMADRAFT_RS20130
uniprot id: H5X5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

882083:SACMADRAFT RS03885
gene id: 882083:SACMADRAFT_RS03885
uniprot id: H5X7C9
names: Similarity
messages: Belongs to the peptidase S33 family.

882083:SACMADRAFT RS08370
gene id: 882083:SACMADRAFT_RS08370
uniprot id: H5X4I1
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

882083:SACMADRAFT RS17985
gene id: 882083:SACMADRAFT_RS17985
uniprot id: H5WZT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

882083:SACMADRAFT RS22715
gene id: 882083:SACMADRAFT_RS22715
uniprot id: H5WWZ0
names: Similarity
messages: Belongs to the peptidase S33 family.

882083:SACMADRAFT RS00035
gene id: 882083:SACMADRAFT_RS00035
uniprot id: H5WX55
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

882083:SACMADRAFT RS15040
gene id: 882083:SACMADRAFT_RS15040
uniprot id: H5X7L3
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

882083:SACMADRAFT RS26905
gene id: 882083:SACMADRAFT_RS26905
uniprot id: H5X912
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

882083:SACMADRAFT RS10815
gene id: 882083:SACMADRAFT_RS10815
uniprot id: H5XBG1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS23695
gene id: 882083:SACMADRAFT_RS23695
uniprot id: H5X020
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

882083:SACMADRAFT RS18970
gene id: 882083:SACMADRAFT_RS18970
uniprot id: H5X2T5
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

882083:SACMADRAFT RS17655
gene id: 882083:SACMADRAFT_RS17655
uniprot id: H5WYU0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

882083:SACMADRAFT RS03490
gene id: 882083:SACMADRAFT_RS03490
uniprot id: H5X6C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

882083:SACMADRAFT RS00570
gene id: 882083:SACMADRAFT_RS00570
uniprot id: H5WYA0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

882083:SACMADRAFT RS07075
gene id: 882083:SACMADRAFT_RS07075
uniprot id: H5X0J6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

882083:SACMADRAFT RS21150
gene id: 882083:SACMADRAFT_RS21150
uniprot id: H5X8T3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS03405
gene id: 882083:SACMADRAFT_RS03405
uniprot id: H5X6A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

882083:SACMADRAFT RS17180
gene id: 882083:SACMADRAFT_RS17180
uniprot id: H5WXR0
names: Similarity
messages: Belongs to the AHA1 family.

882083:SACMADRAFT RS05340
gene id: 882083:SACMADRAFT_RS05340
uniprot id: H5WW95
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS07190
gene id: 882083:SACMADRAFT_RS07190
uniprot id: H5X1F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

882083:SACMADRAFT RS03250
gene id: 882083:SACMADRAFT_RS03250
uniprot id: H5X674
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

882083:SACMADRAFT RS06375
gene id: 882083:SACMADRAFT_RS06375
uniprot id: H5WYJ0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

882083:SACMADRAFT RS22545
gene id: 882083:SACMADRAFT_RS22545
uniprot id: H5WWW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

882083:SACMADRAFT RS16990
gene id: 882083:SACMADRAFT_RS16990
uniprot id: H5WWS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

882083:SACMADRAFT RS05355
gene id: 882083:SACMADRAFT_RS05355
uniprot id: H5WW98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

882083:SACMADRAFT RS17565
gene id: 882083:SACMADRAFT_RS17565
uniprot id: H5WYS1
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS13870
gene id: 882083:SACMADRAFT_RS13870
uniprot id: H5X3Q6
names: Similarity
messages: Belongs to the peptidase S33 family.

882083:SACMADRAFT RS12860
gene id: 882083:SACMADRAFT_RS12860
uniprot id: H5X0S5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

882083:SACMADRAFT RS28325
gene id: 882083:SACMADRAFT_RS28325
uniprot id: H5WX45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

882083:SACMADRAFT RS21335
gene id: 882083:SACMADRAFT_RS21335
uniprot id: H5X8X0
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

882083:SACMADRAFT RS07215
gene id: 882083:SACMADRAFT_RS07215
uniprot id: H5X1F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

882083:SACMADRAFT RS20115
gene id: 882083:SACMADRAFT_RS20115
uniprot id: H5X5V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

882083:SACMADRAFT RS19995
gene id: 882083:SACMADRAFT_RS19995
uniprot id: H5X502
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

882083:SACMADRAFT RS22280
gene id: 882083:SACMADRAFT_RS22280
uniprot id: H5XBU8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS04375
gene id: 882083:SACMADRAFT_RS04375
uniprot id: H5X984
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

882083:SACMADRAFT RS14350
gene id: 882083:SACMADRAFT_RS14350
uniprot id: H5X5L6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

882083:SACMADRAFT RS20775
gene id: 882083:SACMADRAFT_RS20775
uniprot id: H5X7T7
names: Similarity
messages: Belongs to the thioesterase family.

882083:SACMADRAFT RS19005
gene id: 882083:SACMADRAFT_RS19005
uniprot id: H5X2U2
names: Similarity
messages: Belongs to the malate synthase family.

882083:SACMADRAFT RS01765
gene id: 882083:SACMADRAFT_RS01765
uniprot id: H5X272
names: Similarity
messages: Belongs to the EspG family.

882083:SACMADRAFT RS16245
gene id: 882083:SACMADRAFT_RS16245
uniprot id: H5XAN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

882083:SACMADRAFT RS02060
gene id: 882083:SACMADRAFT_RS02060
uniprot id: H5X2D0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

882083:SACMADRAFT RS27255
gene id: 882083:SACMADRAFT_RS27255
uniprot id: H5XA24
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882083:SACMADRAFT RS28155
gene id: 882083:SACMADRAFT_RS28155
uniprot id: H5XC61
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

882083:SACMADRAFT RS17250
gene id: 882083:SACMADRAFT_RS17250
uniprot id: H5WXS4
names: Similarity
messages: Belongs to the CdaR family.

882083:SACMADRAFT RS16690
gene id: 882083:SACMADRAFT_RS16690
uniprot id: H5XBQ5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

882083:SACMADRAFT RS22765
gene id: 882083:SACMADRAFT_RS22765
uniprot id: H5WX00
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

882083:SACMADRAFT RS03920
gene id: 882083:SACMADRAFT_RS03920
uniprot id: H5X867
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS03835
gene id: 882083:SACMADRAFT_RS03835
uniprot id: H5X7B9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

882083:SACMADRAFT RS01670
gene id: 882083:SACMADRAFT_RS01670
uniprot id: H5X1C5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

882083:SACMADRAFT RS15945
gene id: 882083:SACMADRAFT_RS15945
uniprot id: H5X9P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

882083:SACMADRAFT RS23330
gene id: 882083:SACMADRAFT_RS23330
uniprot id: H5WZ09
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

882083:SACMADRAFT RS07360
gene id: 882083:SACMADRAFT_RS07360
uniprot id: H5X1J0
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

882083:SACMADRAFT RS03380
gene id: 882083:SACMADRAFT_RS03380
uniprot id: H5X6A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

882083:SACMADRAFT RS13580
gene id: 882083:SACMADRAFT_RS13580
uniprot id: H5X2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

882083:SACMADRAFT RS19955
gene id: 882083:SACMADRAFT_RS19955
uniprot id: H5X4Z4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

882083:SACMADRAFT RS26450
gene id: 882083:SACMADRAFT_RS26450
uniprot id: H5X801
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS16405
gene id: 882083:SACMADRAFT_RS16405
uniprot id: H5XAR8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

882083:SACMADRAFT RS23115
gene id: 882083:SACMADRAFT_RS23115
uniprot id: H5WY33
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS21100
gene id: 882083:SACMADRAFT_RS21100
uniprot id: H5X8S4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS26460
gene id: 882083:SACMADRAFT_RS26460
uniprot id: H5X803
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS20020
gene id: 882083:SACMADRAFT_RS20020
uniprot id: H5X5T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

882083:SACMADRAFT RS25865
gene id: 882083:SACMADRAFT_RS25865
uniprot id: H5X634
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

882083:SACMADRAFT RS24405
gene id: 882083:SACMADRAFT_RS24405
uniprot id: H5X227
names: Similarity
messages: Belongs to the EspG family.

882083:SACMADRAFT RS15510
gene id: 882083:SACMADRAFT_RS15510
uniprot id: H5X8M6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

882083:SACMADRAFT RS27910
gene id: 882083:SACMADRAFT_RS27910
uniprot id: H5XC11
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

882083:SACMADRAFT RS05710
gene id: 882083:SACMADRAFT_RS05710
uniprot id: H5WXC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

882083:SACMADRAFT RS14630
gene id: 882083:SACMADRAFT_RS14630
uniprot id: H5X5S4
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS01485
gene id: 882083:SACMADRAFT_RS01485
uniprot id: H5X189
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

882083:SACMADRAFT RS07510
gene id: 882083:SACMADRAFT_RS07510
uniprot id: H5X2E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

882083:SACMADRAFT RS16975
gene id: 882083:SACMADRAFT_RS16975
uniprot id: H5WWS0
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS17650
gene id: 882083:SACMADRAFT_RS17650
uniprot id: H5WYT9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

882083:SACMADRAFT RS16660
gene id: 882083:SACMADRAFT_RS16660
uniprot id: H5XBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

882083:SACMADRAFT RS11690
gene id: 882083:SACMADRAFT_RS11690
uniprot id: H5WXN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

882083:SACMADRAFT RS04250
gene id: 882083:SACMADRAFT_RS04250
uniprot id: H5X960
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

882083:SACMADRAFT RS09535
gene id: 882083:SACMADRAFT_RS09535
uniprot id: H5X7J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882083:SACMADRAFT RS10405
gene id: 882083:SACMADRAFT_RS10405
uniprot id: H5XAF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

882083:SACMADRAFT RS06830
gene id: 882083:SACMADRAFT_RS06830
uniprot id: H5X0E7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

882083:SACMADRAFT RS17135
gene id: 882083:SACMADRAFT_RS17135
uniprot id: H5WWU7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

882083:SACMADRAFT RS17090
gene id: 882083:SACMADRAFT_RS17090
uniprot id: H5WWT8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS15230
gene id: 882083:SACMADRAFT_RS15230
uniprot id: H5X7Q0
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

882083:SACMADRAFT RS06475
gene id: 882083:SACMADRAFT_RS06475
uniprot id: H5WZE0
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

882083:SACMADRAFT RS12915
gene id: 882083:SACMADRAFT_RS12915
uniprot id: H5X1L8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS03270
gene id: 882083:SACMADRAFT_RS03270
uniprot id: H5X678
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

882083:SACMADRAFT RS04380
gene id: 882083:SACMADRAFT_RS04380
uniprot id: H5X985
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS08735
gene id: 882083:SACMADRAFT_RS08735
uniprot id: H5X5I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

882083:SACMADRAFT RS06675
gene id: 882083:SACMADRAFT_RS06675
uniprot id: H5WZI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

882083:SACMADRAFT RS04550
gene id: 882083:SACMADRAFT_RS04550
uniprot id: H5X9C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

882083:SACMADRAFT RS16285
gene id: 882083:SACMADRAFT_RS16285
uniprot id: H5XAP4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

882083:SACMADRAFT RS06645
gene id: 882083:SACMADRAFT_RS06645
uniprot id: H5WZH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

882083:SACMADRAFT RS03340
gene id: 882083:SACMADRAFT_RS03340
uniprot id: H5X692
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

882083:SACMADRAFT RS13525
gene id: 882083:SACMADRAFT_RS13525
uniprot id: H5X2R2
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

882083:SACMADRAFT RS05975
gene id: 882083:SACMADRAFT_RS05975
uniprot id: H5WXH6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

882083:SACMADRAFT RS17960
gene id: 882083:SACMADRAFT_RS17960
uniprot id: H5WZT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

882083:SACMADRAFT RS00605
gene id: 882083:SACMADRAFT_RS00605
uniprot id: H5WYA7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

882083:SACMADRAFT RS18110
gene id: 882083:SACMADRAFT_RS18110
uniprot id: H5WZW4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

882083:SACMADRAFT RS27480
gene id: 882083:SACMADRAFT_RS27480
uniprot id: H5XB00
names: Similarity
messages: Belongs to the YciI family.

882083:SACMADRAFT RS20145
gene id: 882083:SACMADRAFT_RS20145
uniprot id: H5X5V7
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS21230
gene id: 882083:SACMADRAFT_RS21230
uniprot id: H5X8U9
names: Similarity
messages: Belongs to the peptidase S8 family.

882083:SACMADRAFT RS10345
gene id: 882083:SACMADRAFT_RS10345
uniprot id: H5XAE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

882083:SACMADRAFT RS23025
gene id: 882083:SACMADRAFT_RS23025
uniprot id: H5WY12
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS17955
gene id: 882083:SACMADRAFT_RS17955
uniprot id: H5WZT3
names: Similarity
messages: Belongs to the carbamate kinase family.

882083:SACMADRAFT RS07430
gene id: 882083:SACMADRAFT_RS07430
uniprot id: H5X1L3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

882083:SACMADRAFT RS14370
gene id: 882083:SACMADRAFT_RS14370
uniprot id: H5X5M0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS21245
gene id: 882083:SACMADRAFT_RS21245
uniprot id: H5X8V2
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

882083:SACMADRAFT RS12235
gene id: 882083:SACMADRAFT_RS12235
uniprot id: H5WZL5
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS04900
gene id: 882083:SACMADRAFT_RS04900
uniprot id: H5XAC8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

882083:SACMADRAFT RS21280
gene id: 882083:SACMADRAFT_RS21280
uniprot id: H5X8V9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

882083:SACMADRAFT RS09850
gene id: 882083:SACMADRAFT_RS09850
uniprot id: H5X8H8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

882083:SACMADRAFT RS16035
gene id: 882083:SACMADRAFT_RS16035
uniprot id: H5X9Q8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS07835
gene id: 882083:SACMADRAFT_RS07835
uniprot id: H5X3E4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS13115
gene id: 882083:SACMADRAFT_RS13115
uniprot id: H5X1Q8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS01635
gene id: 882083:SACMADRAFT_RS01635
uniprot id: H5X1B8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS05605
gene id: 882083:SACMADRAFT_RS05605
uniprot id: H5WWE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

882083:SACMADRAFT RS10115
gene id: 882083:SACMADRAFT_RS10115
uniprot id: H5X9G2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS08835
gene id: 882083:SACMADRAFT_RS08835
uniprot id: H5X5K4
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

882083:SACMADRAFT RS20110
gene id: 882083:SACMADRAFT_RS20110
uniprot id: H5X5V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

882083:SACMADRAFT RS05350
gene id: 882083:SACMADRAFT_RS05350
uniprot id: H5WW97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

882083:SACMADRAFT RS05935
gene id: 882083:SACMADRAFT_RS05935
uniprot id: H5WXG8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

882083:SACMADRAFT RS18850
gene id: 882083:SACMADRAFT_RS18850
uniprot id: H5X1Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

882083:SACMADRAFT RS08070
gene id: 882083:SACMADRAFT_RS08070
uniprot id: H5X3I8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

882083:SACMADRAFT RS17015
gene id: 882083:SACMADRAFT_RS17015
uniprot id: H5WWS8
names: Similarity
messages: Belongs to the TlyA family.

882083:SACMADRAFT RS25000
gene id: 882083:SACMADRAFT_RS25000
uniprot id: H5X402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS26895
gene id: 882083:SACMADRAFT_RS26895
uniprot id: H5X910
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

882083:SACMADRAFT RS04205
gene id: 882083:SACMADRAFT_RS04205
uniprot id: H5X8C1
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

882083:SACMADRAFT RS02795
gene id: 882083:SACMADRAFT_RS02795
uniprot id: H5X4C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882083:SACMADRAFT RS22170
gene id: 882083:SACMADRAFT_RS22170
uniprot id: H5XBS5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

882083:SACMADRAFT RS18200
gene id: 882083:SACMADRAFT_RS18200
uniprot id: H5WZY2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS04435
gene id: 882083:SACMADRAFT_RS04435
uniprot id: H5X996
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

882083:SACMADRAFT RS22270
gene id: 882083:SACMADRAFT_RS22270
uniprot id: H5XBU5
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS03465
gene id: 882083:SACMADRAFT_RS03465
uniprot id: H5X6B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

882083:SACMADRAFT RS18585
gene id: 882083:SACMADRAFT_RS18585
uniprot id: H5X0Z7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

882083:SACMADRAFT RS06490
gene id: 882083:SACMADRAFT_RS06490
uniprot id: H5WZE3
names: Similarity
messages: Belongs to the malate synthase family.

882083:SACMADRAFT RS04295
gene id: 882083:SACMADRAFT_RS04295
uniprot id: H5X969
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

882083:SACMADRAFT RS01270
gene id: 882083:SACMADRAFT_RS01270
uniprot id: H5X0A8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS04020
gene id: 882083:SACMADRAFT_RS04020
uniprot id: H5X887
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS12875
gene id: 882083:SACMADRAFT_RS12875
uniprot id: H5X0S8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

882083:SACMADRAFT RS30405
gene id: 882083:SACMADRAFT_RS30405
uniprot id: H5X4R7
names: Similarity
messages: Belongs to the AHA1 family.

882083:SACMADRAFT RS21680
gene id: 882083:SACMADRAFT_RS21680
uniprot id: H5X9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

882083:SACMADRAFT RS03410
gene id: 882083:SACMADRAFT_RS03410
uniprot id: H5X6A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

882083:SACMADRAFT RS04925
gene id: 882083:SACMADRAFT_RS04925
uniprot id: H5XAD3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS16630
gene id: 882083:SACMADRAFT_RS16630
uniprot id: H5XBP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

882083:SACMADRAFT RS04595
gene id: 882083:SACMADRAFT_RS04595
uniprot id: H5X9C9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS23560
gene id: 882083:SACMADRAFT_RS23560
uniprot id: H5WZ53
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

882083:SACMADRAFT RS02480
gene id: 882083:SACMADRAFT_RS02480
uniprot id: H5X466
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

882083:SACMADRAFT RS27855
gene id: 882083:SACMADRAFT_RS27855
uniprot id: H5XC00
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS27330
gene id: 882083:SACMADRAFT_RS27330
uniprot id: H5XA39
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

882083:SACMADRAFT RS16270
gene id: 882083:SACMADRAFT_RS16270
uniprot id: H5XAP1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882083:SACMADRAFT RS28240
gene id: 882083:SACMADRAFT_RS28240
uniprot id: H5WX29
names: Similarity
messages: Belongs to the Nudix hydrolase family.

882083:SACMADRAFT RS05180
gene id: 882083:SACMADRAFT_RS05180
uniprot id: H5XBB1
names: Similarity
messages: Belongs to the type IB topoisomerase family.

882083:SACMADRAFT RS07340
gene id: 882083:SACMADRAFT_RS07340
uniprot id: H5X1I5
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS03260
gene id: 882083:SACMADRAFT_RS03260
uniprot id: H5X676
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

882083:SACMADRAFT RS20680
gene id: 882083:SACMADRAFT_RS20680
uniprot id: H5X6Y8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

882083:SACMADRAFT RS13215
gene id: 882083:SACMADRAFT_RS13215
uniprot id: H5X1S8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

882083:SACMADRAFT RS13315
gene id: 882083:SACMADRAFT_RS13315
uniprot id: H5X2M2
names: Similarity
messages: Belongs to the universal stress protein A family.

882083:SACMADRAFT RS24450
gene id: 882083:SACMADRAFT_RS24450
uniprot id: H5X236
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS01905
gene id: 882083:SACMADRAFT_RS01905
uniprot id: H5X2A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

882083:SACMADRAFT RS13090
gene id: 882083:SACMADRAFT_RS13090
uniprot id: H5X1Q3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

882083:SACMADRAFT RS13780
gene id: 882083:SACMADRAFT_RS13780
uniprot id: H5X3N9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

882083:SACMADRAFT RS17970
gene id: 882083:SACMADRAFT_RS17970
uniprot id: H5WZT6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS27955
gene id: 882083:SACMADRAFT_RS27955
uniprot id: H5XC20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

882083:SACMADRAFT RS11875
gene id: 882083:SACMADRAFT_RS11875
uniprot id: H5WYL3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882083:SACMADRAFT RS27780
gene id: 882083:SACMADRAFT_RS27780
uniprot id: H5XB59
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS12490
gene id: 882083:SACMADRAFT_RS12490
uniprot id: H5WZR6
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

882083:SACMADRAFT RS24385
gene id: 882083:SACMADRAFT_RS24385
uniprot id: H5X223
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

882083:SACMADRAFT RS01295
gene id: 882083:SACMADRAFT_RS01295
uniprot id: H5X0B3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS11715
gene id: 882083:SACMADRAFT_RS11715
uniprot id: H5WXP3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

882083:SACMADRAFT RS26780
gene id: 882083:SACMADRAFT_RS26780
uniprot id: H5X858
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882083:SACMADRAFT RS23895
gene id: 882083:SACMADRAFT_RS23895
uniprot id: H5X062
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

882083:SACMADRAFT RS23300
gene id: 882083:SACMADRAFT_RS23300
uniprot id: H5WZ03
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
messages: Homodimer.

882083:SACMADRAFT RS26935
gene id: 882083:SACMADRAFT_RS26935
uniprot id: H5X918
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

882083:SACMADRAFT RS24840
gene id: 882083:SACMADRAFT_RS24840
uniprot id: H5X342
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

882083:SACMADRAFT RS06775
gene id: 882083:SACMADRAFT_RS06775
uniprot id: H5X0D7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

882083:SACMADRAFT RS16940
gene id: 882083:SACMADRAFT_RS16940
uniprot id: H5WWR3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

882083:SACMADRAFT RS17120
gene id: 882083:SACMADRAFT_RS17120
uniprot id: H5WWU4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

882083:SACMADRAFT RS08730
gene id: 882083:SACMADRAFT_RS08730
uniprot id: H5X5I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

882083:SACMADRAFT RS14190
gene id: 882083:SACMADRAFT_RS14190
uniprot id: H5X4Q6
names: Similarity
messages: Belongs to the YciI family.

882083:SACMADRAFT RS24205
gene id: 882083:SACMADRAFT_RS24205
uniprot id: H5X157
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS18145
gene id: 882083:SACMADRAFT_RS18145
uniprot id: H5WZX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

882083:SACMADRAFT RS21430
gene id: 882083:SACMADRAFT_RS21430
uniprot id: H5X9S9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

882083:SACMADRAFT RS22190
gene id: 882083:SACMADRAFT_RS22190
uniprot id: H5XBS9
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

882083:SACMADRAFT RS22985
gene id: 882083:SACMADRAFT_RS22985
uniprot id: H5WY04
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882083:SACMADRAFT RS18430
gene id: 882083:SACMADRAFT_RS18430
uniprot id: H5X0W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

882083:SACMADRAFT RS05365
gene id: 882083:SACMADRAFT_RS05365
uniprot id: H5WWA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

882083:SACMADRAFT RS05695
gene id: 882083:SACMADRAFT_RS05695
uniprot id: H5WXB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

882083:SACMADRAFT RS25595
gene id: 882083:SACMADRAFT_RS25595
uniprot id: H5X558
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

882083:SACMADRAFT RS02580
gene id: 882083:SACMADRAFT_RS02580
uniprot id: H5X486
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS19385
gene id: 882083:SACMADRAFT_RS19385
uniprot id: H5X3T8
names: Similarity
messages: Belongs to the CutA family.

882083:SACMADRAFT RS17375
gene id: 882083:SACMADRAFT_RS17375
uniprot id: H5WXU6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS25925
gene id: 882083:SACMADRAFT_RS25925
uniprot id: H5X646
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS24005
gene id: 882083:SACMADRAFT_RS24005
uniprot id: H5X120
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

882083:SACMADRAFT RS24250
gene id: 882083:SACMADRAFT_RS24250
uniprot id: H5X166
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS15850
gene id: 882083:SACMADRAFT_RS15850
uniprot id: H5X9M2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS08515
gene id: 882083:SACMADRAFT_RS08515
uniprot id: H5X4K8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

882083:SACMADRAFT RS23775
gene id: 882083:SACMADRAFT_RS23775
uniprot id: H5X037
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

882083:SACMADRAFT RS18375
gene id: 882083:SACMADRAFT_RS18375
uniprot id: H5X0V4
names: Similarity
messages: Belongs to the ketopantoate reductase family.

882083:SACMADRAFT RS16770
gene id: 882083:SACMADRAFT_RS16770
uniprot id: H5XBR7
names: Similarity
messages: Belongs to the peptidase S33 family.

882083:SACMADRAFT RS18245
gene id: 882083:SACMADRAFT_RS18245
uniprot id: H5WZZ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS27615
gene id: 882083:SACMADRAFT_RS27615
uniprot id: H5XB28
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

882083:SACMADRAFT RS14490
gene id: 882083:SACMADRAFT_RS14490
uniprot id: H5X5P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

882083:SACMADRAFT RS06325
gene id: 882083:SACMADRAFT_RS06325
uniprot id: H5WYI0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

882083:SACMADRAFT RS03220
gene id: 882083:SACMADRAFT_RS03220
uniprot id: H5X669
names: Similarity
messages: Belongs to the UPF0336 family.

882083:SACMADRAFT RS20060
gene id: 882083:SACMADRAFT_RS20060
uniprot id: H5X5U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS07520
gene id: 882083:SACMADRAFT_RS07520
uniprot id: H5X2E9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

882083:SACMADRAFT RS10520
gene id: 882083:SACMADRAFT_RS10520
uniprot id: H5XAH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

882083:SACMADRAFT RS09890
gene id: 882083:SACMADRAFT_RS09890
uniprot id: H5X8I6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS19070
gene id: 882083:SACMADRAFT_RS19070
uniprot id: H5X2V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS00075
gene id: 882083:SACMADRAFT_RS00075
uniprot id: H5WX62
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

882083:SACMADRAFT RS08470
gene id: 882083:SACMADRAFT_RS08470
uniprot id: H5X4K0
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

882083:SACMADRAFT RS16010
gene id: 882083:SACMADRAFT_RS16010
uniprot id: H5X9Q5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

882083:SACMADRAFT RS07330
gene id: 882083:SACMADRAFT_RS07330
uniprot id: H5X1I2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

882083:SACMADRAFT RS26325
gene id: 882083:SACMADRAFT_RS26325
uniprot id: H5X744
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS06270
gene id: 882083:SACMADRAFT_RS06270
uniprot id: H5WYG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

882083:SACMADRAFT RS03935
gene id: 882083:SACMADRAFT_RS03935
uniprot id: H5X870
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

882083:SACMADRAFT RS12620
gene id: 882083:SACMADRAFT_RS12620
uniprot id: H5X0M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

882083:SACMADRAFT RS30730
gene id: 882083:SACMADRAFT_RS30730
uniprot id: H5X382
names: Similarity
messages: Belongs to the Vsr family.

882083:SACMADRAFT RS20100
gene id: 882083:SACMADRAFT_RS20100
uniprot id: H5X5U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

882083:SACMADRAFT RS14730
gene id: 882083:SACMADRAFT_RS14730
uniprot id: H5X6M1
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS06410
gene id: 882083:SACMADRAFT_RS06410
uniprot id: H5WZC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

882083:SACMADRAFT RS14130
gene id: 882083:SACMADRAFT_RS14130
uniprot id: H5X4P4
names: Similarity
messages: Belongs to the YciI family.

882083:SACMADRAFT RS10555
gene id: 882083:SACMADRAFT_RS10555
uniprot id: H5XAI5
names: Similarity
messages: Belongs to the FPG family.

882083:SACMADRAFT RS18510
gene id: 882083:SACMADRAFT_RS18510
uniprot id: H5X0Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

882083:SACMADRAFT RS11150
gene id: 882083:SACMADRAFT_RS11150
uniprot id: H5WWH6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

882083:SACMADRAFT RS09885
gene id: 882083:SACMADRAFT_RS09885
uniprot id: H5X8I5
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

882083:SACMADRAFT RS07600
gene id: 882083:SACMADRAFT_RS07600
uniprot id: H5X2G5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

882083:SACMADRAFT RS11595
gene id: 882083:SACMADRAFT_RS11595
uniprot id: H5WXL8
names: Similarity
messages: Belongs to the FBPase class 2 family.

882083:SACMADRAFT RS10610
gene id: 882083:SACMADRAFT_RS10610
uniprot id: H5XAJ6
names: Similarity
messages: Belongs to the EspG family.

882083:SACMADRAFT RS04625
gene id: 882083:SACMADRAFT_RS04625
uniprot id: H5XA72
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS16435
gene id: 882083:SACMADRAFT_RS16435
uniprot id: H5XAS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

882083:SACMADRAFT RS22445
gene id: 882083:SACMADRAFT_RS22445
uniprot id: H5XBY1
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

882083:SACMADRAFT RS15780
gene id: 882083:SACMADRAFT_RS15780
uniprot id: H5X9K8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS16900
gene id: 882083:SACMADRAFT_RS16900
uniprot id: H5WWQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS03675
gene id: 882083:SACMADRAFT_RS03675
uniprot id: H5X787
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

882083:SACMADRAFT RS06130
gene id: 882083:SACMADRAFT_RS06130
uniprot id: H5WYE3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

882083:SACMADRAFT RS23920
gene id: 882083:SACMADRAFT_RS23920
uniprot id: H5X104
names: Similarity
messages: Belongs to the IlvD/Edd family.

882083:SACMADRAFT RS07515
gene id: 882083:SACMADRAFT_RS07515
uniprot id: H5X2E8
names: Similarity
messages: Belongs to the NodU/CmcH family.

882083:SACMADRAFT RS08180
gene id: 882083:SACMADRAFT_RS08180
uniprot id: H5X4E3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

882083:SACMADRAFT RS18955
gene id: 882083:SACMADRAFT_RS18955
uniprot id: H5X2T2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

882083:SACMADRAFT RS17815
gene id: 882083:SACMADRAFT_RS17815
uniprot id: H5WYX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882083:SACMADRAFT RS24150
gene id: 882083:SACMADRAFT_RS24150
uniprot id: H5X146
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

882083:SACMADRAFT RS27625
gene id: 882083:SACMADRAFT_RS27625
uniprot id: H5XB30
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

882083:SACMADRAFT RS07325
gene id: 882083:SACMADRAFT_RS07325
uniprot id: H5X1I1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

882083:SACMADRAFT RS13180
gene id: 882083:SACMADRAFT_RS13180
uniprot id: H5X1S1
names: Subunit
messages: Monomer.

882083:SACMADRAFT RS08905
gene id: 882083:SACMADRAFT_RS08905
uniprot id: H5X6E2
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

882083:SACMADRAFT RS08400
gene id: 882083:SACMADRAFT_RS08400
uniprot id: H5X4I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

882083:SACMADRAFT RS17115
gene id: 882083:SACMADRAFT_RS17115
uniprot id: H5WWU3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

882083:SACMADRAFT RS27935
gene id: 882083:SACMADRAFT_RS27935
uniprot id: H5XC16
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS03665
gene id: 882083:SACMADRAFT_RS03665
uniprot id: H5X785
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS19860
gene id: 882083:SACMADRAFT_RS19860
uniprot id: H5X4X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

882083:SACMADRAFT RS05280
gene id: 882083:SACMADRAFT_RS05280
uniprot id: H5XBD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

882083:SACMADRAFT RS28160
gene id: 882083:SACMADRAFT_RS28160
uniprot id: H5XC62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

882083:SACMADRAFT RS18465
gene id: 882083:SACMADRAFT_RS18465
uniprot id: H5X0X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS13675
gene id: 882083:SACMADRAFT_RS13675
uniprot id: H5X3L8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

882083:SACMADRAFT RS21840
gene id: 882083:SACMADRAFT_RS21840
uniprot id: H5XAT7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

882083:SACMADRAFT RS06180
gene id: 882083:SACMADRAFT_RS06180
uniprot id: H5WYF3
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS16840
gene id: 882083:SACMADRAFT_RS16840
uniprot id: H5WWP4
names: Similarity
messages: Belongs to the AHA1 family.

882083:SACMADRAFT RS23655
gene id: 882083:SACMADRAFT_RS23655
uniprot id: H5X012
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

882083:SACMADRAFT RS15555
gene id: 882083:SACMADRAFT_RS15555
uniprot id: H5X8N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

882083:SACMADRAFT RS12205
gene id: 882083:SACMADRAFT_RS12205
uniprot id: H5WZL0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882083:SACMADRAFT RS02710
gene id: 882083:SACMADRAFT_RS02710
uniprot id: H5X4B2
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS03855
gene id: 882083:SACMADRAFT_RS03855
uniprot id: H5X7C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

882083:SACMADRAFT RS22025
gene id: 882083:SACMADRAFT_RS22025
uniprot id: H5XAX3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

882083:SACMADRAFT RS08975
gene id: 882083:SACMADRAFT_RS08975
uniprot id: H5X6F6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

882083:SACMADRAFT RS21185
gene id: 882083:SACMADRAFT_RS21185
uniprot id: H5X8U0
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

882083:SACMADRAFT RS08090
gene id: 882083:SACMADRAFT_RS08090
uniprot id: H5X3J2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

882083:SACMADRAFT RS27300
gene id: 882083:SACMADRAFT_RS27300
uniprot id: H5XA33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

882083:SACMADRAFT RS12870
gene id: 882083:SACMADRAFT_RS12870
uniprot id: H5X0S7
names: Similarity
messages: Belongs to the XFP family.

882083:SACMADRAFT RS19155
gene id: 882083:SACMADRAFT_RS19155
uniprot id: H5X2X1
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS00300
gene id: 882083:SACMADRAFT_RS00300
uniprot id: H5WXA3
names: Similarity
messages: Belongs to the GSP E family.

882083:SACMADRAFT RS03425
gene id: 882083:SACMADRAFT_RS03425
uniprot id: H5X6A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

882083:SACMADRAFT RS12105
gene id: 882083:SACMADRAFT_RS12105
uniprot id: H5WYQ8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

882083:SACMADRAFT RS17470
gene id: 882083:SACMADRAFT_RS17470
uniprot id: H5WXW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

882083:SACMADRAFT RS04845
gene id: 882083:SACMADRAFT_RS04845
uniprot id: H5XAB7
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

882083:SACMADRAFT RS01400
gene id: 882083:SACMADRAFT_RS01400
uniprot id: H5X0D5
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS02960
gene id: 882083:SACMADRAFT_RS02960
uniprot id: H5X594
names: Similarity
messages: Belongs to the asparagine synthetase family.

882083:SACMADRAFT RS24660
gene id: 882083:SACMADRAFT_RS24660
uniprot id: H5X306
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS17795
gene id: 882083:SACMADRAFT_RS17795
uniprot id: H5WYW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

882083:SACMADRAFT RS03900
gene id: 882083:SACMADRAFT_RS03900
uniprot id: H5X863
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

882083:SACMADRAFT RS27165
gene id: 882083:SACMADRAFT_RS27165
uniprot id: H5XA07
names: Similarity
messages: Belongs to the HIBADH-related family.

882083:SACMADRAFT RS24110
gene id: 882083:SACMADRAFT_RS24110
uniprot id: H5X138
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

882083:SACMADRAFT RS11785
gene id: 882083:SACMADRAFT_RS11785
uniprot id: H5WXQ6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

882083:SACMADRAFT RS15645
gene id: 882083:SACMADRAFT_RS15645
uniprot id: H5X8Q1
names: Similarity
messages: Belongs to the CsoR family.

882083:SACMADRAFT RS12730
gene id: 882083:SACMADRAFT_RS12730
uniprot id: H5X0P8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS19285
gene id: 882083:SACMADRAFT_RS19285
uniprot id: H5X2Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

882083:SACMADRAFT RS26385
gene id: 882083:SACMADRAFT_RS26385
uniprot id: H5X757
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

882083:SACMADRAFT RS03520
gene id: 882083:SACMADRAFT_RS03520
uniprot id: H5X6C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

882083:SACMADRAFT RS07030
gene id: 882083:SACMADRAFT_RS07030
uniprot id: H5X0I7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS06205
gene id: 882083:SACMADRAFT_RS06205
uniprot id: H5WYF8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS05275
gene id: 882083:SACMADRAFT_RS05275
uniprot id: H5XBD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

882083:SACMADRAFT RS24935
gene id: 882083:SACMADRAFT_RS24935
uniprot id: H5X360
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

882083:SACMADRAFT RS17150
gene id: 882083:SACMADRAFT_RS17150
uniprot id: H5WWV0
names: Similarity
messages: Belongs to the RutC family.

882083:SACMADRAFT RS24520
gene id: 882083:SACMADRAFT_RS24520
uniprot id: H5X249
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

882083:SACMADRAFT RS23080
gene id: 882083:SACMADRAFT_RS23080
uniprot id: H5WY23
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

882083:SACMADRAFT RS09250
gene id: 882083:SACMADRAFT_RS09250
uniprot id: H5X7D8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS03655
gene id: 882083:SACMADRAFT_RS03655
uniprot id: H5X783
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

882083:SACMADRAFT RS12145
gene id: 882083:SACMADRAFT_RS12145
uniprot id: H5WYR5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882083:SACMADRAFT RS10395
gene id: 882083:SACMADRAFT_RS10395
uniprot id: H5XAF3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

882083:SACMADRAFT RS19050
gene id: 882083:SACMADRAFT_RS19050
uniprot id: H5X2V0
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS28215
gene id: 882083:SACMADRAFT_RS28215
uniprot id: H5WX25
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

882083:SACMADRAFT RS23005
gene id: 882083:SACMADRAFT_RS23005
uniprot id: H5WY08
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS23435
gene id: 882083:SACMADRAFT_RS23435
uniprot id: H5WZ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS06505
gene id: 882083:SACMADRAFT_RS06505
uniprot id: H5WZE6
names: Similarity
messages: Belongs to the hyi family.

882083:SACMADRAFT RS07615
gene id: 882083:SACMADRAFT_RS07615
uniprot id: H5X2G8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

882083:SACMADRAFT RS22750
gene id: 882083:SACMADRAFT_RS22750
uniprot id: H5WWZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS02265
gene id: 882083:SACMADRAFT_RS02265
uniprot id: H5X397
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

882083:SACMADRAFT RS11020
gene id: 882083:SACMADRAFT_RS11020
uniprot id: H5XBJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

882083:SACMADRAFT RS02285
gene id: 882083:SACMADRAFT_RS02285
uniprot id: H5X3A1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

882083:SACMADRAFT RS13685
gene id: 882083:SACMADRAFT_RS13685
uniprot id: H5X3M0
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

882083:SACMADRAFT RS22840
gene id: 882083:SACMADRAFT_RS22840
uniprot id: H5WX14
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

882083:SACMADRAFT RS21250
gene id: 882083:SACMADRAFT_RS21250
uniprot id: H5X8V3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

882083:SACMADRAFT RS16620
gene id: 882083:SACMADRAFT_RS16620
uniprot id: H5XBP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS10950
gene id: 882083:SACMADRAFT_RS10950
uniprot id: H5XBI5
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

882083:SACMADRAFT RS09045
gene id: 882083:SACMADRAFT_RS09045
uniprot id: H5X6H0
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

882083:SACMADRAFT RS08510
gene id: 882083:SACMADRAFT_RS08510
uniprot id: H5X4K7
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

882083:SACMADRAFT RS03530
gene id: 882083:SACMADRAFT_RS03530
uniprot id: H5X6D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

882083:SACMADRAFT RS22135
gene id: 882083:SACMADRAFT_RS22135
uniprot id: H5XAZ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS08505
gene id: 882083:SACMADRAFT_RS08505
uniprot id: H5X4K6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

882083:SACMADRAFT RS27130
gene id: 882083:SACMADRAFT_RS27130
uniprot id: H5X957
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS15545
gene id: 882083:SACMADRAFT_RS15545
uniprot id: H5X8N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

882083:SACMADRAFT RS23710
gene id: 882083:SACMADRAFT_RS23710
uniprot id: H5X023
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS05255
gene id: 882083:SACMADRAFT_RS05255
uniprot id: H5XBC7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS16855
gene id: 882083:SACMADRAFT_RS16855
uniprot id: H5WWP7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

882083:SACMADRAFT RS01660
gene id: 882083:SACMADRAFT_RS01660
uniprot id: H5X1C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

882083:SACMADRAFT RS09010
gene id: 882083:SACMADRAFT_RS09010
uniprot id: H5X6G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS24735
gene id: 882083:SACMADRAFT_RS24735
uniprot id: H5X322
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

882083:SACMADRAFT RS14765
gene id: 882083:SACMADRAFT_RS14765
uniprot id: H5X6M8
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

882083:SACMADRAFT RS04165
gene id: 882083:SACMADRAFT_RS04165
uniprot id: H5X8B3
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS28070
gene id: 882083:SACMADRAFT_RS28070
uniprot id: H5XC44
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

882083:SACMADRAFT RS06680
gene id: 882083:SACMADRAFT_RS06680
uniprot id: H5WZI1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

882083:SACMADRAFT RS27285
gene id: 882083:SACMADRAFT_RS27285
uniprot id: H5XA30
names: Similarity
messages: Belongs to the AHA1 family.

882083:SACMADRAFT RS21660
gene id: 882083:SACMADRAFT_RS21660
uniprot id: H5X9X4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

882083:SACMADRAFT RS13750
gene id: 882083:SACMADRAFT_RS13750
uniprot id: H5X3N3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

882083:SACMADRAFT RS26590
gene id: 882083:SACMADRAFT_RS26590
uniprot id: H5X824
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS07470
gene id: 882083:SACMADRAFT_RS07470
uniprot id: H5X1L1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

882083:SACMADRAFT RS23385
gene id: 882083:SACMADRAFT_RS23385
uniprot id: H5WZ20
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

882083:SACMADRAFT RS27325
gene id: 882083:SACMADRAFT_RS27325
uniprot id: H5XA38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS19500
gene id: 882083:SACMADRAFT_RS19500
uniprot id: H5X3W4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS06380
gene id: 882083:SACMADRAFT_RS06380
uniprot id: H5WYJ1
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

882083:SACMADRAFT RS08430
gene id: 882083:SACMADRAFT_RS08430
uniprot id: H5X4J1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

882083:SACMADRAFT RS24580
gene id: 882083:SACMADRAFT_RS24580
uniprot id: H5X260
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

882083:SACMADRAFT RS22540
gene id: 882083:SACMADRAFT_RS22540
uniprot id: H5WWV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

882083:SACMADRAFT RS14700
gene id: 882083:SACMADRAFT_RS14700
uniprot id: H5X6L5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS16120
gene id: 882083:SACMADRAFT_RS16120
uniprot id: H5X9S7
names: Similarity
messages: Belongs to the GPI family.

882083:SACMADRAFT RS06970
gene id: 882083:SACMADRAFT_RS06970
uniprot id: H5X0H6
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

882083:SACMADRAFT RS21885
gene id: 882083:SACMADRAFT_RS21885
uniprot id: H5XAU6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

882083:SACMADRAFT RS27595
gene id: 882083:SACMADRAFT_RS27595
uniprot id: H5XB24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS16370
gene id: 882083:SACMADRAFT_RS16370
uniprot id: H5XAR1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS16115
gene id: 882083:SACMADRAFT_RS16115
uniprot id: H5X9S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

882083:SACMADRAFT RS06095
gene id: 882083:SACMADRAFT_RS06095
uniprot id: H5WYD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS21925
gene id: 882083:SACMADRAFT_RS21925
uniprot id: H5XAV4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

882083:SACMADRAFT RS15180
gene id: 882083:SACMADRAFT_RS15180
uniprot id: H5X7P2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

882083:SACMADRAFT RS11265
gene id: 882083:SACMADRAFT_RS11265
uniprot id: H5WWJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

882083:SACMADRAFT RS14450
gene id: 882083:SACMADRAFT_RS14450
uniprot id: H5X5N6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS08245
gene id: 882083:SACMADRAFT_RS08245
uniprot id: H5X4F6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

882083:SACMADRAFT RS22845
gene id: 882083:SACMADRAFT_RS22845
uniprot id: H5WX15
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

882083:SACMADRAFT RS28110
gene id: 882083:SACMADRAFT_RS28110
uniprot id: H5XC53
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

882083:SACMADRAFT RS02790
gene id: 882083:SACMADRAFT_RS02790
uniprot id: H5X4C8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882083:SACMADRAFT RS08920
gene id: 882083:SACMADRAFT_RS08920
uniprot id: H5X6E5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

882083:SACMADRAFT RS08490
gene id: 882083:SACMADRAFT_RS08490
uniprot id: H5X4K3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

882083:SACMADRAFT RS26835
gene id: 882083:SACMADRAFT_RS26835
uniprot id: H5X8Z8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS27455
gene id: 882083:SACMADRAFT_RS27455
uniprot id: H5XA65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

882083:SACMADRAFT RS01975
gene id: 882083:SACMADRAFT_RS01975
uniprot id: H5X2B4
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

882083:SACMADRAFT RS01155
gene id: 882083:SACMADRAFT_RS01155
uniprot id: H5X085
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS02920
gene id: 882083:SACMADRAFT_RS02920
uniprot id: H5X586
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

882083:SACMADRAFT RS29705
gene id: 882083:SACMADRAFT_RS29705
uniprot id: H5X7T4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS23100
gene id: 882083:SACMADRAFT_RS23100
uniprot id: H5WY30
names: Similarity
messages: Belongs to the citrate synthase family.

882083:SACMADRAFT RS09020
gene id: 882083:SACMADRAFT_RS09020
uniprot id: H5X6G5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

882083:SACMADRAFT RS04440
gene id: 882083:SACMADRAFT_RS04440
uniprot id: H5X997
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

882083:SACMADRAFT RS06605
gene id: 882083:SACMADRAFT_RS06605
uniprot id: H5WZG6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

882083:SACMADRAFT RS12595
gene id: 882083:SACMADRAFT_RS12595
uniprot id: H5X0M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane

882083:SACMADRAFT RS27155
gene id: 882083:SACMADRAFT_RS27155
uniprot id: H5XA05
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882083:SACMADRAFT RS08990
gene id: 882083:SACMADRAFT_RS08990
uniprot id: H5X6F9
names: Similarity
messages: Belongs to the Fur family.

882083:SACMADRAFT RS24035
gene id: 882083:SACMADRAFT_RS24035
uniprot id: H5X125
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

882083:SACMADRAFT RS06690
gene id: 882083:SACMADRAFT_RS06690
uniprot id: H5WZI3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

882083:SACMADRAFT RS21795
gene id: 882083:SACMADRAFT_RS21795
uniprot id: H5XA00
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

882083:SACMADRAFT RS22375
gene id: 882083:SACMADRAFT_RS22375
uniprot id: H5XBW7
names: Similarity
messages: Belongs to the peptidase S33 family.

882083:SACMADRAFT RS06755
gene id: 882083:SACMADRAFT_RS06755
uniprot id: H5WZJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

882083:SACMADRAFT RS06415
gene id: 882083:SACMADRAFT_RS06415
uniprot id: H5WZC7
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

882083:SACMADRAFT RS20890
gene id: 882083:SACMADRAFT_RS20890
uniprot id: H5X7V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS07480
gene id: 882083:SACMADRAFT_RS07480
uniprot id: H5X2E1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

882083:SACMADRAFT RS07635
gene id: 882083:SACMADRAFT_RS07635
uniprot id: H5X2H2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

882083:SACMADRAFT RS15085
gene id: 882083:SACMADRAFT_RS15085
uniprot id: H5X7M2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS25025
gene id: 882083:SACMADRAFT_RS25025
uniprot id: H5X406
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS27475
gene id: 882083:SACMADRAFT_RS27475
uniprot id: H5XAZ9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882083:SACMADRAFT RS07175
gene id: 882083:SACMADRAFT_RS07175
uniprot id: H5X1F0
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

882083:SACMADRAFT RS02990
gene id: 882083:SACMADRAFT_RS02990
uniprot id: H5X5A0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

882083:SACMADRAFT RS03500
gene id: 882083:SACMADRAFT_RS03500
uniprot id: H5X6C5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

882083:SACMADRAFT RS02615
gene id: 882083:SACMADRAFT_RS02615
uniprot id: H5X493
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

882083:SACMADRAFT RS24295
gene id: 882083:SACMADRAFT_RS24295
uniprot id: H5X205
names: Similarity
messages: Belongs to the peptidase M1 family.

882083:SACMADRAFT RS05530
gene id: 882083:SACMADRAFT_RS05530
uniprot id: H5WWD1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

882083:SACMADRAFT RS07415
gene id: 882083:SACMADRAFT_RS07415
uniprot id: H5X1K2
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

882083:SACMADRAFT RS27785
gene id: 882083:SACMADRAFT_RS27785
uniprot id: H5XB60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

882083:SACMADRAFT RS17095
gene id: 882083:SACMADRAFT_RS17095
uniprot id: H5WWT9
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

882083:SACMADRAFT RS14580
gene id: 882083:SACMADRAFT_RS14580
uniprot id: H5X5R3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS19140
gene id: 882083:SACMADRAFT_RS19140
uniprot id: H5X2W8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS04645
gene id: 882083:SACMADRAFT_RS04645
uniprot id: H5XA76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

882083:SACMADRAFT RS10415
gene id: 882083:SACMADRAFT_RS10415
uniprot id: H5XAF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

882083:SACMADRAFT RS16715
gene id: 882083:SACMADRAFT_RS16715
uniprot id: H5XBR0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

882083:SACMADRAFT RS17990
gene id: 882083:SACMADRAFT_RS17990
uniprot id: H5WZU0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

882083:SACMADRAFT RS26775
gene id: 882083:SACMADRAFT_RS26775
uniprot id: H5X857
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882083:SACMADRAFT RS07380
gene id: 882083:SACMADRAFT_RS07380
uniprot id: H5X1J4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

882083:SACMADRAFT RS06305
gene id: 882083:SACMADRAFT_RS06305
uniprot id: H5WYH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

882083:SACMADRAFT RS16200
gene id: 882083:SACMADRAFT_RS16200
uniprot id: H5XAM7
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS08240
gene id: 882083:SACMADRAFT_RS08240
uniprot id: H5X4F5
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS05535
gene id: 882083:SACMADRAFT_RS05535
uniprot id: H5WWD2
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

882083:SACMADRAFT RS06745
gene id: 882083:SACMADRAFT_RS06745
uniprot id: H5WZJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

882083:SACMADRAFT RS16540
gene id: 882083:SACMADRAFT_RS16540
uniprot id: H5XBM5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

882083:SACMADRAFT RS24180
gene id: 882083:SACMADRAFT_RS24180
uniprot id: H5X152
names: Similarity
messages: Belongs to the TPP enzyme family.

882083:SACMADRAFT RS21575
gene id: 882083:SACMADRAFT_RS21575
uniprot id: H5X9V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS20430
gene id: 882083:SACMADRAFT_RS20430
uniprot id: H5X6T7
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS15000
gene id: 882083:SACMADRAFT_RS15000
uniprot id: H5X6S6
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS20965
gene id: 882083:SACMADRAFT_RS20965
uniprot id: H5X7X2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

882083:SACMADRAFT RS06215
gene id: 882083:SACMADRAFT_RS06215
uniprot id: H5WYG0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

882083:SACMADRAFT RS15470
gene id: 882083:SACMADRAFT_RS15470
uniprot id: H5X8L8
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

882083:SACMADRAFT RS11755
gene id: 882083:SACMADRAFT_RS11755
uniprot id: H5WXQ1
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

882083:SACMADRAFT RS00030
gene id: 882083:SACMADRAFT_RS00030
uniprot id: H5WX54
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

882083:SACMADRAFT RS25460
gene id: 882083:SACMADRAFT_RS25460
uniprot id: H5X530
names: Subcellular Location Annotation
messages: Cytoplasm

882083:SACMADRAFT RS23525
gene id: 882083:SACMADRAFT_RS23525
uniprot id: H5WZ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

882083:SACMADRAFT RS18460
gene id: 882083:SACMADRAFT_RS18460
uniprot id: H5X0X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS03430
gene id: 882083:SACMADRAFT_RS03430
uniprot id: H5X6B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

882083:SACMADRAFT RS03850
gene id: 882083:SACMADRAFT_RS03850
uniprot id: H5X0W4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

882083:SACMADRAFT RS21670
gene id: 882083:SACMADRAFT_RS21670
uniprot id: H5X9X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

882083:SACMADRAFT RS20735
gene id: 882083:SACMADRAFT_RS20735
uniprot id: H5X7S9
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS08145
gene id: 882083:SACMADRAFT_RS08145
uniprot id: H5X3K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

882083:SACMADRAFT RS26215
gene id: 882083:SACMADRAFT_RS26215
uniprot id: H5X726
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS16125
gene id: 882083:SACMADRAFT_RS16125
uniprot id: H5X9S8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS03710
gene id: 882083:SACMADRAFT_RS03710
uniprot id: H5X794
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

882083:SACMADRAFT RS16175
gene id: 882083:SACMADRAFT_RS16175
uniprot id: H5XAM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

882083:SACMADRAFT RS17825
gene id: 882083:SACMADRAFT_RS17825
uniprot id: H5WYX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

882083:SACMADRAFT RS24850
gene id: 882083:SACMADRAFT_RS24850
uniprot id: H5X344
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882083:SACMADRAFT RS19575
gene id: 882083:SACMADRAFT_RS19575
uniprot id: H5X3X9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

882083:SACMADRAFT RS06160
gene id: 882083:SACMADRAFT_RS06160
uniprot id: H5WYE9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

882083:SACMADRAFT RS27345
gene id: 882083:SACMADRAFT_RS27345
uniprot id: H5XA42
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS05085
gene id: 882083:SACMADRAFT_RS05085
uniprot id: H5XB95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

882083:SACMADRAFT RS13900
gene id: 882083:SACMADRAFT_RS13900
uniprot id: H5X3R2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

882083:SACMADRAFT RS21105
gene id: 882083:SACMADRAFT_RS21105
uniprot id: H5X8S5
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

882083:SACMADRAFT RS06845
gene id: 882083:SACMADRAFT_RS06845
uniprot id: H5X0F0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

882083:SACMADRAFT RS18065
gene id: 882083:SACMADRAFT_RS18065
uniprot id: H5WZV5
names: Similarity
messages: Belongs to the FPG family.

882083:SACMADRAFT RS17080
gene id: 882083:SACMADRAFT_RS17080
uniprot id: H5WWT6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS26470
gene id: 882083:SACMADRAFT_RS26470
uniprot id: H5X805
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882083:SACMADRAFT RS05625
gene id: 882083:SACMADRAFT_RS05625
uniprot id: H5WWE8
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

882083:SACMADRAFT RS18905
gene id: 882083:SACMADRAFT_RS18905
uniprot id: H5X1Z3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS14795
gene id: 882083:SACMADRAFT_RS14795
uniprot id: H5X6N4
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS09585
gene id: 882083:SACMADRAFT_RS09585
uniprot id: H5X7K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882083:SACMADRAFT RS12670
gene id: 882083:SACMADRAFT_RS12670
uniprot id: H5X0N6
names: Similarity
messages: Belongs to the TmoD/XamoD family.

882083:SACMADRAFT RS17480
gene id: 882083:SACMADRAFT_RS17480
uniprot id: H5WXW6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882083:SACMADRAFT RS26655
gene id: 882083:SACMADRAFT_RS26655
uniprot id: H5X835
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

882083:SACMADRAFT RS22460
gene id: 882083:SACMADRAFT_RS22460
uniprot id: H5XBY4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

882083:SACMADRAFT RS13990
gene id: 882083:SACMADRAFT_RS13990
uniprot id: H5X4L5
names: Similarity
messages: Belongs to the peptidase M24B family.

882083:SACMADRAFT RS10860
gene id: 882083:SACMADRAFT_RS10860
uniprot id: H5XBG9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Heterodimer of an alpha and a beta chain.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS19010
gene id: 882083:SACMADRAFT_RS19010
uniprot id: H5X2U3
names: Cofactor
messages: Can also use Mn(2+) ion.

882083:SACMADRAFT RS12090
gene id: 882083:SACMADRAFT_RS12090
uniprot id: H5WYQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS16315
gene id: 882083:SACMADRAFT_RS16315
uniprot id: H5XAQ0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

882083:SACMADRAFT RS12305
gene id: 882083:SACMADRAFT_RS12305
uniprot id: H5WZM9
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS21410
gene id: 882083:SACMADRAFT_RS21410
uniprot id: H5X8Y8
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

882083:SACMADRAFT RS03725
gene id: 882083:SACMADRAFT_RS03725
uniprot id: H5X797
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

882083:SACMADRAFT RS04660
gene id: 882083:SACMADRAFT_RS04660
uniprot id: H5XA79
names: Similarity
messages: Belongs to the band 7/mec-2 family.

882083:SACMADRAFT RS15775
gene id: 882083:SACMADRAFT_RS15775
uniprot id: H5X9K7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS05685
gene id: 882083:SACMADRAFT_RS05685
uniprot id: H5WXB5
names: Similarity
messages: Belongs to the universal stress protein A family.

882083:SACMADRAFT RS27430
gene id: 882083:SACMADRAFT_RS27430
uniprot id: H5XA60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

882083:SACMADRAFT RS06700
gene id: 882083:SACMADRAFT_RS06700
uniprot id: H5WZI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

882083:SACMADRAFT RS11580
gene id: 882083:SACMADRAFT_RS11580
uniprot id: H5WXL5
names: Similarity
messages: Belongs to the peptidase M1 family.

882083:SACMADRAFT RS01830
gene id: 882083:SACMADRAFT_RS01830
uniprot id: H5X286
names: Similarity
messages: Belongs to the polysaccharide synthase family.

882083:SACMADRAFT RS08615
gene id: 882083:SACMADRAFT_RS08615
uniprot id: H5X5G0
names: Similarity
messages: Belongs to the CdaR family.

882083:SACMADRAFT RS19640
gene id: 882083:SACMADRAFT_RS19640
uniprot id: H5X3Z2
names: Subcellular Location Annotation
messages: Cell membrane

882083:SACMADRAFT RS20945
gene id: 882083:SACMADRAFT_RS20945
uniprot id: H5X7W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS06910
gene id: 882083:SACMADRAFT_RS06910
uniprot id: H5X0G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

882083:SACMADRAFT RS20035
gene id: 882083:SACMADRAFT_RS20035
uniprot id: H5X5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS16985
gene id: 882083:SACMADRAFT_RS16985
uniprot id: H5WWS2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS23440
gene id: 882083:SACMADRAFT_RS23440
uniprot id: H5WZ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS16385
gene id: 882083:SACMADRAFT_RS16385
uniprot id: H5XAR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

882083:SACMADRAFT RS03480
gene id: 882083:SACMADRAFT_RS03480
uniprot id: H5X6C1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

882083:SACMADRAFT RS05830
gene id: 882083:SACMADRAFT_RS05830
uniprot id: H5WXE7
names: Similarity
messages: Belongs to the creatininase superfamily.

882083:SACMADRAFT RS16110
gene id: 882083:SACMADRAFT_RS16110
uniprot id: H5X9S3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

882083:SACMADRAFT RS28090
gene id: 882083:SACMADRAFT_RS28090
uniprot id: H5XC48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

882083:SACMADRAFT RS09985
gene id: 882083:SACMADRAFT_RS09985
uniprot id: H5X9D7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

882083:SACMADRAFT RS22995
gene id: 882083:SACMADRAFT_RS22995
uniprot id: H5WY06
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS28750
gene id: 882083:SACMADRAFT_RS28750
uniprot id: H5X715
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

882083:SACMADRAFT RS26885
gene id: 882083:SACMADRAFT_RS26885
uniprot id: H5X908
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS19165
gene id: 882083:SACMADRAFT_RS19165
uniprot id: H5X2X3
names: Similarity
messages: Belongs to the UPF0045 family.

882083:SACMADRAFT RS13510
gene id: 882083:SACMADRAFT_RS13510
uniprot id: H5X2Q9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS07315
gene id: 882083:SACMADRAFT_RS07315
uniprot id: H5X1H9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

882083:SACMADRAFT RS01455
gene id: 882083:SACMADRAFT_RS01455
uniprot id: H5X182
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

882083:SACMADRAFT RS09425
gene id: 882083:SACMADRAFT_RS09425
uniprot id: H5X7H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

882083:SACMADRAFT RS09565
gene id: 882083:SACMADRAFT_RS09565
uniprot id: H5X7J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882083:SACMADRAFT RS23410
gene id: 882083:SACMADRAFT_RS23410
uniprot id: H5WZ25
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

882083:SACMADRAFT RS17675
gene id: 882083:SACMADRAFT_RS17675
uniprot id: H5WYU4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

882083:SACMADRAFT RS09860
gene id: 882083:SACMADRAFT_RS09860
uniprot id: H5X8I0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

882083:SACMADRAFT RS09420
gene id: 882083:SACMADRAFT_RS09420
uniprot id: H5X7K4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

882083:SACMADRAFT RS06020
gene id: 882083:SACMADRAFT_RS06020
uniprot id: H5WXI5
names: Similarity
messages: Belongs to the glutamate synthase family.

882083:SACMADRAFT RS05990
gene id: 882083:SACMADRAFT_RS05990
uniprot id: H5WXH9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

882083:SACMADRAFT RS02750
gene id: 882083:SACMADRAFT_RS02750
uniprot id: H5X4C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882083:SACMADRAFT RS13260
gene id: 882083:SACMADRAFT_RS13260
uniprot id: H5X2L1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882083:SACMADRAFT RS08960
gene id: 882083:SACMADRAFT_RS08960
uniprot id: H5X6F3
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS08255
gene id: 882083:SACMADRAFT_RS08255
uniprot id: H5X4F8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

882083:SACMADRAFT RS28135
gene id: 882083:SACMADRAFT_RS28135
uniprot id: H5XC57
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

882083:SACMADRAFT RS19920
gene id: 882083:SACMADRAFT_RS19920
uniprot id: H5X4Y7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

882083:SACMADRAFT RS20195
gene id: 882083:SACMADRAFT_RS20195
uniprot id: H5X5W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

882083:SACMADRAFT RS19580
gene id: 882083:SACMADRAFT_RS19580
uniprot id: H5X3Y0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS06890
gene id: 882083:SACMADRAFT_RS06890
uniprot id: H5X0F9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS06460
gene id: 882083:SACMADRAFT_RS06460
uniprot id: H5WZD7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

882083:SACMADRAFT RS25205
gene id: 882083:SACMADRAFT_RS25205
uniprot id: H5X442
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS21070
gene id: 882083:SACMADRAFT_RS21070
uniprot id: H5X7Z3
names: Similarity
messages: Belongs to the TPP enzyme family.

882083:SACMADRAFT RS26220
gene id: 882083:SACMADRAFT_RS26220
uniprot id: H5X727
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS04185
gene id: 882083:SACMADRAFT_RS04185
uniprot id: H5X8B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

882083:SACMADRAFT RS18175
gene id: 882083:SACMADRAFT_RS18175
uniprot id: H5WZX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS14620
gene id: 882083:SACMADRAFT_RS14620
uniprot id: H5X5S2
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS09840
gene id: 882083:SACMADRAFT_RS09840
uniprot id: H5X8H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

882083:SACMADRAFT RS17870
gene id: 882083:SACMADRAFT_RS17870
uniprot id: H5WYY2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

882083:SACMADRAFT RS18520
gene id: 882083:SACMADRAFT_RS18520
uniprot id: H5X0Y4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

882083:SACMADRAFT RS21375
gene id: 882083:SACMADRAFT_RS21375
uniprot id: H5X8Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

882083:SACMADRAFT RS15605
gene id: 882083:SACMADRAFT_RS15605
uniprot id: H5X8P5
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

882083:SACMADRAFT RS05130
gene id: 882083:SACMADRAFT_RS05130
uniprot id: H5XBA4
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

882083:SACMADRAFT RS07185
gene id: 882083:SACMADRAFT_RS07185
uniprot id: H5X1F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

882083:SACMADRAFT RS06435
gene id: 882083:SACMADRAFT_RS06435
uniprot id: H5WZD2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

882083:SACMADRAFT RS06665
gene id: 882083:SACMADRAFT_RS06665
uniprot id: H5WZH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS01470
gene id: 882083:SACMADRAFT_RS01470
uniprot id: H5X185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

882083:SACMADRAFT RS24825
gene id: 882083:SACMADRAFT_RS24825
uniprot id: H5X339
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

882083:SACMADRAFT RS03510
gene id: 882083:SACMADRAFT_RS03510
uniprot id: H5X6C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

882083:SACMADRAFT RS08065
gene id: 882083:SACMADRAFT_RS08065
uniprot id: H5X3I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

882083:SACMADRAFT RS14315
gene id: 882083:SACMADRAFT_RS14315
uniprot id: H5X4S8
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS16490
gene id: 882083:SACMADRAFT_RS16490
uniprot id: H5XBL5
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS15550
gene id: 882083:SACMADRAFT_RS15550
uniprot id: H5X8N3
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

882083:SACMADRAFT RS03535
gene id: 882083:SACMADRAFT_RS03535
uniprot id: H5X6D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

882083:SACMADRAFT RS06470
gene id: 882083:SACMADRAFT_RS06470
uniprot id: H5WZD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

882083:SACMADRAFT RS20930
gene id: 882083:SACMADRAFT_RS20930
uniprot id: H5X7W5
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS05705
gene id: 882083:SACMADRAFT_RS05705
uniprot id: H5WXB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

882083:SACMADRAFT RS23485
gene id: 882083:SACMADRAFT_RS23485
uniprot id: H5WZ40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

882083:SACMADRAFT RS22440
gene id: 882083:SACMADRAFT_RS22440
uniprot id: H5XBY0
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS05285
gene id: 882083:SACMADRAFT_RS05285
uniprot id: H5XBD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

882083:SACMADRAFT RS23220
gene id: 882083:SACMADRAFT_RS23220
uniprot id: H5WYY7
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS07245
gene id: 882083:SACMADRAFT_RS07245
uniprot id: H5X1G4
names: Similarity
messages: Belongs to the peptidase C40 family.

882083:SACMADRAFT RS24645
gene id: 882083:SACMADRAFT_RS24645
uniprot id: H5X303
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

882083:SACMADRAFT RS04840
gene id: 882083:SACMADRAFT_RS04840
uniprot id: H5XAB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

882083:SACMADRAFT RS16375
gene id: 882083:SACMADRAFT_RS16375
uniprot id: H5XAR2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

882083:SACMADRAFT RS03620
gene id: 882083:SACMADRAFT_RS03620
uniprot id: H5X776
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

882083:SACMADRAFT RS01120
gene id: 882083:SACMADRAFT_RS01120
uniprot id: H5X078
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS27930
gene id: 882083:SACMADRAFT_RS27930
uniprot id: H5XC15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS12160
gene id: 882083:SACMADRAFT_RS12160
uniprot id: H5WZK1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

882083:SACMADRAFT RS02995
gene id: 882083:SACMADRAFT_RS02995
uniprot id: H5X5A1
names: Similarity
messages: Belongs to the UPF0234 family.

882083:SACMADRAFT RS11640
gene id: 882083:SACMADRAFT_RS11640
uniprot id: H5WXM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

882083:SACMADRAFT RS10075
gene id: 882083:SACMADRAFT_RS10075
uniprot id: H5X9F5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS02390
gene id: 882083:SACMADRAFT_RS02390
uniprot id: H5X3C2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882083:SACMADRAFT RS12405
gene id: 882083:SACMADRAFT_RS12405
uniprot id: H5WZP9
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS11660
gene id: 882083:SACMADRAFT_RS11660
uniprot id: H5WXN2
names: Similarity
messages: Belongs to the FBPase class 2 family.

882083:SACMADRAFT RS18855
gene id: 882083:SACMADRAFT_RS18855
uniprot id: H5X1Y5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

882083:SACMADRAFT RS03945
gene id: 882083:SACMADRAFT_RS03945
uniprot id: H5X872
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882083:SACMADRAFT RS25125
gene id: 882083:SACMADRAFT_RS25125
uniprot id: H5X426
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

882083:SACMADRAFT RS03455
gene id: 882083:SACMADRAFT_RS03455
uniprot id: H5X6B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

882083:SACMADRAFT RS05145
gene id: 882083:SACMADRAFT_RS05145
uniprot id: H5XBA7
names: Similarity
messages: Belongs to the glutamine synthetase family.

882083:SACMADRAFT RS16410
gene id: 882083:SACMADRAFT_RS16410
uniprot id: H5XAR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

882083:SACMADRAFT RS01605
gene id: 882083:SACMADRAFT_RS01605
uniprot id: H5X1B2
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS09580
gene id: 882083:SACMADRAFT_RS09580
uniprot id: H5X7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

882083:SACMADRAFT RS11980
gene id: 882083:SACMADRAFT_RS11980
uniprot id: H5WYN4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882083:SACMADRAFT RS12340
gene id: 882083:SACMADRAFT_RS12340
uniprot id: H5WZN5
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS02780
gene id: 882083:SACMADRAFT_RS02780
uniprot id: H5X4C6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882083:SACMADRAFT RS06565
gene id: 882083:SACMADRAFT_RS06565
uniprot id: H5WZF8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

882083:SACMADRAFT RS20170
gene id: 882083:SACMADRAFT_RS20170
uniprot id: H5X5W2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

882083:SACMADRAFT RS02820
gene id: 882083:SACMADRAFT_RS02820
uniprot id: H5X4D4
names: Similarity
messages: Belongs to the EspG family.

882083:SACMADRAFT RS06285
gene id: 882083:SACMADRAFT_RS06285
uniprot id: H5WYH2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

882083:SACMADRAFT RS02740
gene id: 882083:SACMADRAFT_RS02740
uniprot id: H5X4B8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

882083:SACMADRAFT RS18235
gene id: 882083:SACMADRAFT_RS18235
uniprot id: H5WZY9
names: Similarity
messages: Belongs to the histone deacetylase family.

882083:SACMADRAFT RS01530
gene id: 882083:SACMADRAFT_RS01530
uniprot id: H5X198
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

882083:SACMADRAFT RS21055
gene id: 882083:SACMADRAFT_RS21055
uniprot id: H5X7Y9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

882083:SACMADRAFT RS19625
gene id: 882083:SACMADRAFT_RS19625
uniprot id: H5X3Y9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

882083:SACMADRAFT RS15295
gene id: 882083:SACMADRAFT_RS15295
uniprot id: H5X7R1
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS22140
gene id: 882083:SACMADRAFT_RS22140
uniprot id: H5XAZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

882083:SACMADRAFT RS21110
gene id: 882083:SACMADRAFT_RS21110
uniprot id: H5X8S6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS20980
gene id: 882083:SACMADRAFT_RS20980
uniprot id: H5X7X5
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS07965
gene id: 882083:SACMADRAFT_RS07965
uniprot id: H5X3H0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

882083:SACMADRAFT RS24400
gene id: 882083:SACMADRAFT_RS24400
uniprot id: H5X226
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

882083:SACMADRAFT RS05740
gene id: 882083:SACMADRAFT_RS05740
uniprot id: H5WXC6
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS09550
gene id: 882083:SACMADRAFT_RS09550
uniprot id: H5X7J6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882083:SACMADRAFT RS19295
gene id: 882083:SACMADRAFT_RS19295
uniprot id: H5X2Z5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

882083:SACMADRAFT RS24065
gene id: 882083:SACMADRAFT_RS24065
uniprot id: H5X130
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

882083:SACMADRAFT RS07750
gene id: 882083:SACMADRAFT_RS07750
uniprot id: H5X2J5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

882083:SACMADRAFT RS17110
gene id: 882083:SACMADRAFT_RS17110
uniprot id: H5WWU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

882083:SACMADRAFT RS18310
gene id: 882083:SACMADRAFT_RS18310
uniprot id: H5X0U1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

882083:SACMADRAFT RS16645
gene id: 882083:SACMADRAFT_RS16645
uniprot id: H5XBP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

882083:SACMADRAFT RS08915
gene id: 882083:SACMADRAFT_RS08915
uniprot id: H5X6E4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

882083:SACMADRAFT RS07490
gene id: 882083:SACMADRAFT_RS07490
uniprot id: H5X2E3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS12755
gene id: 882083:SACMADRAFT_RS12755
uniprot id: H5X0Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS12910
gene id: 882083:SACMADRAFT_RS12910
uniprot id: H5X1L7
names: Similarity
messages: Belongs to the YciI family.

882083:SACMADRAFT RS21315
gene id: 882083:SACMADRAFT_RS21315
uniprot id: H5X8W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

882083:SACMADRAFT RS22790
gene id: 882083:SACMADRAFT_RS22790
uniprot id: H5WX05
names: Similarity
messages: Belongs to the EspG family.

882083:SACMADRAFT RS05955
gene id: 882083:SACMADRAFT_RS05955
uniprot id: H5WXH2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

882083:SACMADRAFT RS16390
gene id: 882083:SACMADRAFT_RS16390
uniprot id: H5XAR5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

882083:SACMADRAFT RS21610
gene id: 882083:SACMADRAFT_RS21610
uniprot id: H5X9W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.
messages: Membrane

882083:SACMADRAFT RS17010
gene id: 882083:SACMADRAFT_RS17010
uniprot id: H5WWS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS02965
gene id: 882083:SACMADRAFT_RS02965
uniprot id: H5X595
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS11240
gene id: 882083:SACMADRAFT_RS11240
uniprot id: H5WWJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

882083:SACMADRAFT RS15890
gene id: 882083:SACMADRAFT_RS15890
uniprot id: H5X9N1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

882083:SACMADRAFT RS13730
gene id: 882083:SACMADRAFT_RS13730
uniprot id: H5X3M9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

882083:SACMADRAFT RS21740
gene id: 882083:SACMADRAFT_RS21740
uniprot id: H5X9Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

882083:SACMADRAFT RS16455
gene id: 882083:SACMADRAFT_RS16455
uniprot id: H5XAS5
names: Similarity
messages: Belongs to the peptidase A24 family.

882083:SACMADRAFT RS01385
gene id: 882083:SACMADRAFT_RS01385
uniprot id: H5X0D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

882083:SACMADRAFT RS16170
gene id: 882083:SACMADRAFT_RS16170
uniprot id: H5XAM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

882083:SACMADRAFT RS06760
gene id: 882083:SACMADRAFT_RS06760
uniprot id: H5WZJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

882083:SACMADRAFT RS09930
gene id: 882083:SACMADRAFT_RS09930
uniprot id: H5X8J5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

882083:SACMADRAFT RS13895
gene id: 882083:SACMADRAFT_RS13895
uniprot id: H5X3R1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

882083:SACMADRAFT RS27860
gene id: 882083:SACMADRAFT_RS27860
uniprot id: H5XC01
names: Similarity
messages: Belongs to the leucine-binding protein family.

882083:SACMADRAFT RS22185
gene id: 882083:SACMADRAFT_RS22185
uniprot id: H5XBS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

882083:SACMADRAFT RS19400
gene id: 882083:SACMADRAFT_RS19400
uniprot id: H5X3U4
names: Similarity
messages: Belongs to the universal stress protein A family.

882083:SACMADRAFT RS00585
gene id: 882083:SACMADRAFT_RS00585
uniprot id: H5WYA3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

882083:SACMADRAFT RS13935
gene id: 882083:SACMADRAFT_RS13935
uniprot id: H5X3R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

882083:SACMADRAFT RS05965
gene id: 882083:SACMADRAFT_RS05965
uniprot id: H5WXH4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

882083:SACMADRAFT RS03765
gene id: 882083:SACMADRAFT_RS03765
uniprot id: H5X7A5
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

882083:SACMADRAFT RS04385
gene id: 882083:SACMADRAFT_RS04385
uniprot id: H5X986
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

882083:SACMADRAFT RS10225
gene id: 882083:SACMADRAFT_RS10225
uniprot id: H5X9I4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

882083:SACMADRAFT RS07375
gene id: 882083:SACMADRAFT_RS07375
uniprot id: H5X1J3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

882083:SACMADRAFT RS17745
gene id: 882083:SACMADRAFT_RS17745
uniprot id: H5WYV8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

882083:SACMADRAFT RS26210
gene id: 882083:SACMADRAFT_RS26210
uniprot id: H5X725
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS13850
gene id: 882083:SACMADRAFT_RS13850
uniprot id: H5X3Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

882083:SACMADRAFT RS24775
gene id: 882083:SACMADRAFT_RS24775
uniprot id: H5X329
names: Similarity
messages: Belongs to the Dps family.

882083:SACMADRAFT RS05520
gene id: 882083:SACMADRAFT_RS05520
uniprot id: H5WWC9
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

882083:SACMADRAFT RS16255
gene id: 882083:SACMADRAFT_RS16255
uniprot id: H5XAN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

882083:SACMADRAFT RS24425
gene id: 882083:SACMADRAFT_RS24425
uniprot id: H5X231
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

882083:SACMADRAFT RS10715
gene id: 882083:SACMADRAFT_RS10715
uniprot id: H5XBE0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

882083:SACMADRAFT RS07280
gene id: 882083:SACMADRAFT_RS07280
uniprot id: H5X1H1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS10505
gene id: 882083:SACMADRAFT_RS10505
uniprot id: H5XAH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

882083:SACMADRAFT RS21945
gene id: 882083:SACMADRAFT_RS21945
uniprot id: H5XAV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

882083:SACMADRAFT RS18890
gene id: 882083:SACMADRAFT_RS18890
uniprot id: H5X200
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

882083:SACMADRAFT RS15255
gene id: 882083:SACMADRAFT_RS15255
uniprot id: H5X7Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS04085
gene id: 882083:SACMADRAFT_RS04085
uniprot id: H5X8A1
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

882083:SACMADRAFT RS08450
gene id: 882083:SACMADRAFT_RS08450
uniprot id: H5X4J6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS01795
gene id: 882083:SACMADRAFT_RS01795
uniprot id: H5X279
names: Similarity
messages: Belongs to the ABC transporter superfamily.

882083:SACMADRAFT RS16085
gene id: 882083:SACMADRAFT_RS16085
uniprot id: H5X9R8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

882083:SACMADRAFT RS09155
gene id: 882083:SACMADRAFT_RS09155
uniprot id: H5X6J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

882083:SACMADRAFT RS07385
gene id: 882083:SACMADRAFT_RS07385
uniprot id: H5X1J6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS23355
gene id: 882083:SACMADRAFT_RS23355
uniprot id: H5WZ14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

882083:SACMADRAFT RS19245
gene id: 882083:SACMADRAFT_RS19245
uniprot id: H5X2Y7
names: Similarity
messages: Belongs to the universal stress protein A family.

882083:SACMADRAFT RS23450
gene id: 882083:SACMADRAFT_RS23450
uniprot id: H5WZ33
names: Similarity
messages: Belongs to the YciI family.

882083:SACMADRAFT RS08105
gene id: 882083:SACMADRAFT_RS08105
uniprot id: H5X3J6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS10180
gene id: 882083:SACMADRAFT_RS10180
uniprot id: H5X9H5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS17940
gene id: 882083:SACMADRAFT_RS17940
uniprot id: H5WZT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

882083:SACMADRAFT RS10045
gene id: 882083:SACMADRAFT_RS10045
uniprot id: H5X9E9
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS00730
gene id: 882083:SACMADRAFT_RS00730
uniprot id: H5WZ62
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS28195
gene id: 882083:SACMADRAFT_RS28195
uniprot id: H5WX21
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS19215
gene id: 882083:SACMADRAFT_RS19215
uniprot id: H5X2Y1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

882083:SACMADRAFT RS12955
gene id: 882083:SACMADRAFT_RS12955
uniprot id: H5X1M6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

882083:SACMADRAFT RS02645
gene id: 882083:SACMADRAFT_RS02645
uniprot id: H5X499
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

882083:SACMADRAFT RS21685
gene id: 882083:SACMADRAFT_RS21685
uniprot id: H5X9X9
names: Similarity
messages: Belongs to the FBPase class 2 family.

882083:SACMADRAFT RS18165
gene id: 882083:SACMADRAFT_RS18165
uniprot id: H5WZX5
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS03375
gene id: 882083:SACMADRAFT_RS03375
uniprot id: H5X699
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

882083:SACMADRAFT RS10550
gene id: 882083:SACMADRAFT_RS10550
uniprot id: H5XAI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

882083:SACMADRAFT RS05190
gene id: 882083:SACMADRAFT_RS05190
uniprot id: H5XBB3
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS21620
gene id: 882083:SACMADRAFT_RS21620
uniprot id: H5X9W7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

882083:SACMADRAFT RS02805
gene id: 882083:SACMADRAFT_RS02805
uniprot id: H5X4D1
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS14035
gene id: 882083:SACMADRAFT_RS14035
uniprot id: H5X4M4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS14995
gene id: 882083:SACMADRAFT_RS14995
uniprot id: H5X6S3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

882083:SACMADRAFT RS07980
gene id: 882083:SACMADRAFT_RS07980
uniprot id: H5X3H3
names: Similarity
messages: Belongs to the peptidase C40 family.

882083:SACMADRAFT RS07735
gene id: 882083:SACMADRAFT_RS07735
uniprot id: H5X2J2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

882083:SACMADRAFT RS27675
gene id: 882083:SACMADRAFT_RS27675
uniprot id: H5XB40
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS22215
gene id: 882083:SACMADRAFT_RS22215
uniprot id: H5XBT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS21475
gene id: 882083:SACMADRAFT_RS21475
uniprot id: H5X9T8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

882083:SACMADRAFT RS11190
gene id: 882083:SACMADRAFT_RS11190
uniprot id: H5WWI4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

882083:SACMADRAFT RS19410
gene id: 882083:SACMADRAFT_RS19410
uniprot id: H5X3U7
names: Similarity
messages: Belongs to the CapA family.

882083:SACMADRAFT RS24805
gene id: 882083:SACMADRAFT_RS24805
uniprot id: H5X335
names: Subunit
messages: Homodimer.

882083:SACMADRAFT RS08360
gene id: 882083:SACMADRAFT_RS08360
uniprot id: H5X4H9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

882083:SACMADRAFT RS13055
gene id: 882083:SACMADRAFT_RS13055
uniprot id: H5X1P6
names: Similarity
messages: Belongs to the universal stress protein A family.

882083:SACMADRAFT RS04915
gene id: 882083:SACMADRAFT_RS04915
uniprot id: H5XAD1
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS07285
gene id: 882083:SACMADRAFT_RS07285
uniprot id: H5X1H2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS06950
gene id: 882083:SACMADRAFT_RS06950
uniprot id: H5X0H2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

882083:SACMADRAFT RS16555
gene id: 882083:SACMADRAFT_RS16555
uniprot id: H5XBM8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

882083:SACMADRAFT RS27750
gene id: 882083:SACMADRAFT_RS27750
uniprot id: H5XB53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

882083:SACMADRAFT RS07135
gene id: 882083:SACMADRAFT_RS07135
uniprot id: H5X1E2
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

882083:SACMADRAFT RS25260
gene id: 882083:SACMADRAFT_RS25260
uniprot id: H5X451
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

882083:SACMADRAFT RS08100
gene id: 882083:SACMADRAFT_RS08100
uniprot id: H5X3J5
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS09605
gene id: 882083:SACMADRAFT_RS09605
uniprot id: H5X8D1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

882083:SACMADRAFT RS24455
gene id: 882083:SACMADRAFT_RS24455
uniprot id: H5X237
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

882083:SACMADRAFT RS02700
gene id: 882083:SACMADRAFT_RS02700
uniprot id: H5X4B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

882083:SACMADRAFT RS03585
gene id: 882083:SACMADRAFT_RS03585
uniprot id: H5X769
names: Similarity
messages: Belongs to the heat shock protein 70 family.

882083:SACMADRAFT RS23870
gene id: 882083:SACMADRAFT_RS23870
uniprot id: H5X056
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

882083:SACMADRAFT RS15790
gene id: 882083:SACMADRAFT_RS15790
uniprot id: H5X9L0
names: Similarity
messages: Belongs to the CutA family.

882083:SACMADRAFT RS10190
gene id: 882083:SACMADRAFT_RS10190
uniprot id: H5X9H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

882083:SACMADRAFT RS07805
gene id: 882083:SACMADRAFT_RS07805
uniprot id: H5X2K6
names: Similarity
messages: Belongs to the cytochrome P450 family.

882083:SACMADRAFT RS11335
gene id: 882083:SACMADRAFT_RS11335
uniprot id: H5WWL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

882083:SACMADRAFT RS10670
gene id: 882083:SACMADRAFT_RS10670
uniprot id: H5XAK6
names: Similarity
messages: Belongs to the arsA ATPase family.

882083:SACMADRAFT RS03745
gene id: 882083:SACMADRAFT_RS03745
uniprot id: H5X7A1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

882083:SACMADRAFT RS06995
gene id: 882083:SACMADRAFT_RS06995
uniprot id: H5X0I0
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS30765
gene id: 882083:SACMADRAFT_RS30765
uniprot id: H5WXH1
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

882083:SACMADRAFT RS15865
gene id: 882083:SACMADRAFT_RS15865
uniprot id: H5X9M5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS02985
gene id: 882083:SACMADRAFT_RS02985
uniprot id: H5X599
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS24120
gene id: 882083:SACMADRAFT_RS24120
uniprot id: H5X140
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

882083:SACMADRAFT RS13890
gene id: 882083:SACMADRAFT_RS13890
uniprot id: H5X3R0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

882083:SACMADRAFT RS08740
gene id: 882083:SACMADRAFT_RS08740
uniprot id: H5X5I5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

882083:SACMADRAFT RS04360
gene id: 882083:SACMADRAFT_RS04360
uniprot id: H5X981
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

882083:SACMADRAFT RS13320
gene id: 882083:SACMADRAFT_RS13320
uniprot id: H5X2M3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

882083:SACMADRAFT RS06085
gene id: 882083:SACMADRAFT_RS06085
uniprot id: H5WYD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

882083:SACMADRAFT RS21510
gene id: 882083:SACMADRAFT_RS21510
uniprot id: H5X9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS18650
gene id: 882083:SACMADRAFT_RS18650
uniprot id: H5X1U3
names: Similarity
messages: Belongs to the glutamate synthase family.

882083:SACMADRAFT RS05185
gene id: 882083:SACMADRAFT_RS05185
uniprot id: H5XBB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

882083:SACMADRAFT RS21040
gene id: 882083:SACMADRAFT_RS21040
uniprot id: H5X7Y6
names: Subcellular Location Annotation
messages: Cell membrane

882083:SACMADRAFT RS25350
gene id: 882083:SACMADRAFT_RS25350
uniprot id: H5X510
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS21690
gene id: 882083:SACMADRAFT_RS21690
uniprot id: H5X9Y0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS15635
gene id: 882083:SACMADRAFT_RS15635
uniprot id: H5X8P9
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS09990
gene id: 882083:SACMADRAFT_RS09990
uniprot id: H5X9D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS00260
gene id: 882083:SACMADRAFT_RS00260
uniprot id: H5WX95
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

882083:SACMADRAFT RS21310
gene id: 882083:SACMADRAFT_RS21310
uniprot id: H5X8W5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

882083:SACMADRAFT RS10485
gene id: 882083:SACMADRAFT_RS10485
uniprot id: H5XAH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

882083:SACMADRAFT RS22550
gene id: 882083:SACMADRAFT_RS22550
uniprot id: H5WWW1
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS00325
gene id: 882083:SACMADRAFT_RS00325
uniprot id: H5WXA8
names: Similarity
messages: Belongs to the peptidase A24 family.

882083:SACMADRAFT RS07180
gene id: 882083:SACMADRAFT_RS07180
uniprot id: H5X1F1
names: Similarity
messages: Belongs to the asparagine synthetase family.

882083:SACMADRAFT RS20175
gene id: 882083:SACMADRAFT_RS20175
uniprot id: H5X5W3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS05555
gene id: 882083:SACMADRAFT_RS05555
uniprot id: H5WWD6
names: Similarity
messages: Belongs to the peptidase A31 family.

882083:SACMADRAFT RS18130
gene id: 882083:SACMADRAFT_RS18130
uniprot id: H5WZW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

882083:SACMADRAFT RS14605
gene id: 882083:SACMADRAFT_RS14605
uniprot id: H5X5R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

882083:SACMADRAFT RS21345
gene id: 882083:SACMADRAFT_RS21345
uniprot id: H5X8X2
names: Similarity
messages: Belongs to the EspG family.

882083:SACMADRAFT RS15720
gene id: 882083:SACMADRAFT_RS15720
uniprot id: H5X8R5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

882083:SACMADRAFT RS04320
gene id: 882083:SACMADRAFT_RS04320
uniprot id: H5X974
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

882083:SACMADRAFT RS19180
gene id: 882083:SACMADRAFT_RS19180
uniprot id: H5X2X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

882083:SACMADRAFT RS16000
gene id: 882083:SACMADRAFT_RS16000
uniprot id: H5X9Q3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

882083:SACMADRAFT RS06480
gene id: 882083:SACMADRAFT_RS06480
uniprot id: H5WZE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

882083:SACMADRAFT RS04245
gene id: 882083:SACMADRAFT_RS04245
uniprot id: H5X959
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS23705
gene id: 882083:SACMADRAFT_RS23705
uniprot id: H5X022
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

882083:SACMADRAFT RS17160
gene id: 882083:SACMADRAFT_RS17160
uniprot id: H5WWV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

882083:SACMADRAFT RS11575
gene id: 882083:SACMADRAFT_RS11575
uniprot id: H5WXL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

882083:SACMADRAFT RS04605
gene id: 882083:SACMADRAFT_RS04605
uniprot id: H5XA68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

882083:SACMADRAFT RS15475
gene id: 882083:SACMADRAFT_RS15475
uniprot id: H5X8L9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

882083:SACMADRAFT RS22830
gene id: 882083:SACMADRAFT_RS22830
uniprot id: H5WX12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

882083:SACMADRAFT RS13285
gene id: 882083:SACMADRAFT_RS13285
uniprot id: H5X2L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS10145
gene id: 882083:SACMADRAFT_RS10145
uniprot id: H5X9G8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

882083:SACMADRAFT RS19175
gene id: 882083:SACMADRAFT_RS19175
uniprot id: H5X2X5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS20215
gene id: 882083:SACMADRAFT_RS20215
uniprot id: H5X5X1
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS12995
gene id: 882083:SACMADRAFT_RS12995
uniprot id: H5X1N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

882083:SACMADRAFT RS18425
gene id: 882083:SACMADRAFT_RS18425
uniprot id: H5X0W4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

882083:SACMADRAFT RS05200
gene id: 882083:SACMADRAFT_RS05200
uniprot id: H5XBB5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

882083:SACMADRAFT RS23345
gene id: 882083:SACMADRAFT_RS23345
uniprot id: H5WZ12
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

882083:SACMADRAFT RS24810
gene id: 882083:SACMADRAFT_RS24810
uniprot id: H5X336
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

882083:SACMADRAFT RS24440
gene id: 882083:SACMADRAFT_RS24440
uniprot id: H5X234
names: Similarity
messages: Belongs to the peptidase S13 family.

882083:SACMADRAFT RS30970
gene id: 882083:SACMADRAFT_RS30970
uniprot id: H5WWQ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS04640
gene id: 882083:SACMADRAFT_RS04640
uniprot id: H5XA75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

882083:SACMADRAFT RS26055
gene id: 882083:SACMADRAFT_RS26055
uniprot id: H5X6Z9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

882083:SACMADRAFT RS28125
gene id: 882083:SACMADRAFT_RS28125
uniprot id: H5XC56
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

882083:SACMADRAFT RS28275
gene id: 882083:SACMADRAFT_RS28275
uniprot id: H5WX35
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

882083:SACMADRAFT RS21695
gene id: 882083:SACMADRAFT_RS21695
uniprot id: H5X9Y1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

882083:SACMADRAFT RS13645
gene id: 882083:SACMADRAFT_RS13645
uniprot id: H5X3L2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

882083:SACMADRAFT RS10960
gene id: 882083:SACMADRAFT_RS10960
uniprot id: H5XBI7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS14625
gene id: 882083:SACMADRAFT_RS14625
uniprot id: H5X5S3
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS12795
gene id: 882083:SACMADRAFT_RS12795
uniprot id: H5X0R1
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

882083:SACMADRAFT RS27265
gene id: 882083:SACMADRAFT_RS27265
uniprot id: H5XA26
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

882083:SACMADRAFT RS26750
gene id: 882083:SACMADRAFT_RS26750
uniprot id: H5X852
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

882083:SACMADRAFT RS00975
gene id: 882083:SACMADRAFT_RS00975
uniprot id: H5WZA6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS13650
gene id: 882083:SACMADRAFT_RS13650
uniprot id: H5X3L3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

882083:SACMADRAFT RS00295
gene id: 882083:SACMADRAFT_RS00295
uniprot id: H5WXA2
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS02225
gene id: 882083:SACMADRAFT_RS02225
uniprot id: H5X389
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS22600
gene id: 882083:SACMADRAFT_RS22600
uniprot id: H5WWW8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

882083:SACMADRAFT RS03595
gene id: 882083:SACMADRAFT_RS03595
uniprot id: H5X771
names: Similarity
messages: Belongs to the WXG100 family.

882083:SACMADRAFT RS06230
gene id: 882083:SACMADRAFT_RS06230
uniprot id: H5WYG3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

882083:SACMADRAFT RS22000
gene id: 882083:SACMADRAFT_RS22000
uniprot id: H5XAW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

882083:SACMADRAFT RS25275
gene id: 882083:SACMADRAFT_RS25275
uniprot id: H5X454
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

882083:SACMADRAFT RS17975
gene id: 882083:SACMADRAFT_RS17975
uniprot id: H5WZT7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

882083:SACMADRAFT RS09560
gene id: 882083:SACMADRAFT_RS09560
uniprot id: H5X7J8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

882083:SACMADRAFT RS24085
gene id: 882083:SACMADRAFT_RS24085
uniprot id: H5X134
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS27685
gene id: 882083:SACMADRAFT_RS27685
uniprot id: H5XB42
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS16515
gene id: 882083:SACMADRAFT_RS16515
uniprot id: H5XBM0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

882083:SACMADRAFT RS04615
gene id: 882083:SACMADRAFT_RS04615
uniprot id: H5XA70
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS05090
gene id: 882083:SACMADRAFT_RS05090
uniprot id: H5XB96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

882083:SACMADRAFT RS11530
gene id: 882083:SACMADRAFT_RS11530
uniprot id: H5WXK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS10810
gene id: 882083:SACMADRAFT_RS10810
uniprot id: H5XBG0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

882083:SACMADRAFT RS16640
gene id: 882083:SACMADRAFT_RS16640
uniprot id: H5XBP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

882083:SACMADRAFT RS13910
gene id: 882083:SACMADRAFT_RS13910
uniprot id: H5X3R4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

882083:SACMADRAFT RS28435
gene id: 882083:SACMADRAFT_RS28435
uniprot id: H5WXF0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

882083:SACMADRAFT RS26855
gene id: 882083:SACMADRAFT_RS26855
uniprot id: H5X902
names: Similarity
messages: Belongs to the MmpS family.

882083:SACMADRAFT RS23520
gene id: 882083:SACMADRAFT_RS23520
uniprot id: H5WZ47
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

882083:SACMADRAFT RS02665
gene id: 882083:SACMADRAFT_RS02665
uniprot id: H5X4A3
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS01210
gene id: 882083:SACMADRAFT_RS01210
uniprot id: H5X096
names: Similarity
messages: Belongs to the EccD/Snm4 family.

882083:SACMADRAFT RS13725
gene id: 882083:SACMADRAFT_RS13725
uniprot id: H5X3M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS12035
gene id: 882083:SACMADRAFT_RS12035
uniprot id: H5WYP5
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

882083:SACMADRAFT RS08195
gene id: 882083:SACMADRAFT_RS08195
uniprot id: H5X4E6
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS08335
gene id: 882083:SACMADRAFT_RS08335
uniprot id: H5X4H4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

882083:SACMADRAFT RS04210
gene id: 882083:SACMADRAFT_RS04210
uniprot id: H5X8C2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

882083:SACMADRAFT RS25575
gene id: 882083:SACMADRAFT_RS25575
uniprot id: H5X554
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

882083:SACMADRAFT RS15185
gene id: 882083:SACMADRAFT_RS15185
uniprot id: H5X7P3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

882083:SACMADRAFT RS05550
gene id: 882083:SACMADRAFT_RS05550
uniprot id: H5WWD5
names: Similarity
messages: Belongs to the HupF/HypC family.

882083:SACMADRAFT RS13110
gene id: 882083:SACMADRAFT_RS13110
uniprot id: H5X1Q7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

882083:SACMADRAFT RS03730
gene id: 882083:SACMADRAFT_RS03730
uniprot id: H5X798
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

882083:SACMADRAFT RS08210
gene id: 882083:SACMADRAFT_RS08210
uniprot id: H5X4E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

882083:SACMADRAFT RS13555
gene id: 882083:SACMADRAFT_RS13555
uniprot id: H5X2R8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

882083:SACMADRAFT RS24270
gene id: 882083:SACMADRAFT_RS24270
uniprot id: H5X170
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

882083:SACMADRAFT RS17100
gene id: 882083:SACMADRAFT_RS17100
uniprot id: H5WWU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

882083:SACMADRAFT RS06365
gene id: 882083:SACMADRAFT_RS06365
uniprot id: H5WYI8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

882083:SACMADRAFT RS21650
gene id: 882083:SACMADRAFT_RS21650
uniprot id: H5X9X2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

882083:SACMADRAFT RS11780
gene id: 882083:SACMADRAFT_RS11780
uniprot id: H5WXQ5
names: Subcellular Location Annotation
messages: Membrane

882083:SACMADRAFT RS24140
gene id: 882083:SACMADRAFT_RS24140
uniprot id: H5X144
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

882083:SACMADRAFT RS12550
gene id: 882083:SACMADRAFT_RS12550
uniprot id: H5X0L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

882083:SACMADRAFT RS05055
gene id: 882083:SACMADRAFT_RS05055
uniprot id: H5XB89
names: Similarity
messages: Belongs to the peptidase C40 family.

882083:SACMADRAFT RS03485
gene id: 882083:SACMADRAFT_RS03485
uniprot id: H5X6C2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

882083:SACMADRAFT RS16265
gene id: 882083:SACMADRAFT_RS16265
uniprot id: H5XAP0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

882083:SACMADRAFT RS23830
gene id: 882083:SACMADRAFT_RS23830
uniprot id: H5X048
names: Similarity
messages: Belongs to the IucA/IucC family.

882083:SACMADRAFT RS02405
gene id: 882083:SACMADRAFT_RS02405
uniprot id: H5X3C5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.