880074:BARVI RS11095
gene id: 880074:BARVI_RS11095
uniprot id: W0EUP0
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS09705
gene id: 880074:BARVI_RS09705
uniprot id: W0EQH8
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS01200
gene id: 880074:BARVI_RS01200
uniprot id: W0ELQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

880074:BARVI RS08910
gene id: 880074:BARVI_RS08910
uniprot id: W0ETL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

880074:BARVI RS09545
gene id: 880074:BARVI_RS09545
uniprot id: W0EUV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

880074:BARVI RS00585
gene id: 880074:BARVI_RS00585
uniprot id: W0EL68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

880074:BARVI RS02885
gene id: 880074:BARVI_RS02885
uniprot id: W0EME6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

880074:BARVI RS00990
gene id: 880074:BARVI_RS00990
uniprot id: W0EQ74
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

880074:BARVI RS03360
gene id: 880074:BARVI_RS03360
uniprot id: W0ES53
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS08095
gene id: 880074:BARVI_RS08095
uniprot id: W0EUA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

880074:BARVI RS01515
gene id: 880074:BARVI_RS01515
uniprot id: W0ELV0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

880074:BARVI RS08585
gene id: 880074:BARVI_RS08585
uniprot id: W0ETH9
names: Similarity
messages: Belongs to the HSP15 family.

880074:BARVI RS12305
gene id: 880074:BARVI_RS12305
uniprot id: W0ERN1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS05595
gene id: 880074:BARVI_RS05595
uniprot id: W0ES54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

880074:BARVI RS12610
gene id: 880074:BARVI_RS12610
uniprot id: W0EV96
names: Similarity
messages: Belongs to the SusD family.

880074:BARVI RS04935
gene id: 880074:BARVI_RS04935
uniprot id: W0ENC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

880074:BARVI RS03885
gene id: 880074:BARVI_RS03885
uniprot id: W0ERB5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

880074:BARVI RS00055
gene id: 880074:BARVI_RS00055
uniprot id: W0EL42
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

880074:BARVI RS11205
gene id: 880074:BARVI_RS11205
uniprot id: W0ER40
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

880074:BARVI RS06510
gene id: 880074:BARVI_RS06510
uniprot id: W0EP13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

880074:BARVI RS05250
gene id: 880074:BARVI_RS05250
uniprot id: W0ET76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

880074:BARVI RS04145
gene id: 880074:BARVI_RS04145
uniprot id: W0ESF9
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS11015
gene id: 880074:BARVI_RS11015
uniprot id: W0EW00
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS03295
gene id: 880074:BARVI_RS03295
uniprot id: W0ES42
names: Similarity
messages: Belongs to the peptidase M13 family.

880074:BARVI RS10690
gene id: 880074:BARVI_RS10690
uniprot id: W0EVH3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

880074:BARVI RS06995
gene id: 880074:BARVI_RS06995
uniprot id: W0ETQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

880074:BARVI RS05425
gene id: 880074:BARVI_RS05425
uniprot id: W0END1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

880074:BARVI RS07735
gene id: 880074:BARVI_RS07735
uniprot id: W0EUE9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

880074:BARVI RS02410
gene id: 880074:BARVI_RS02410
uniprot id: W0EM84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

880074:BARVI RS05580
gene id: 880074:BARVI_RS05580
uniprot id: W0ETC6
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

880074:BARVI RS07755
gene id: 880074:BARVI_RS07755
uniprot id: W0EU59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

880074:BARVI RS05825
gene id: 880074:BARVI_RS05825
uniprot id: W0ET89
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

880074:BARVI RS10435
gene id: 880074:BARVI_RS10435
uniprot id: W0EQV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

880074:BARVI RS00555
gene id: 880074:BARVI_RS00555
uniprot id: W0EL63
names: Similarity
messages: Belongs to the RutC family.

880074:BARVI RS07840
gene id: 880074:BARVI_RS07840
uniprot id: W0EPP7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

880074:BARVI RS08940
gene id: 880074:BARVI_RS08940
uniprot id: W0ETM1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

880074:BARVI RS11010
gene id: 880074:BARVI_RS11010
uniprot id: W0ER16
names: Similarity
messages: Belongs to the UPF0111 family.

880074:BARVI RS11110
gene id: 880074:BARVI_RS11110
uniprot id: W0EW12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

880074:BARVI RS08020
gene id: 880074:BARVI_RS08020
uniprot id: W0EU90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

880074:BARVI RS04745
gene id: 880074:BARVI_RS04745
uniprot id: W0ERT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

880074:BARVI RS09560
gene id: 880074:BARVI_RS09560
uniprot id: W0EV67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

880074:BARVI RS04095
gene id: 880074:BARVI_RS04095
uniprot id: W0EMW9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880074:BARVI RS06705
gene id: 880074:BARVI_RS06705
uniprot id: W0ETT9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880074:BARVI RS04090
gene id: 880074:BARVI_RS04090
uniprot id: W0ESN1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880074:BARVI RS08115
gene id: 880074:BARVI_RS08115
uniprot id: W0ETB6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

880074:BARVI RS10740
gene id: 880074:BARVI_RS10740
uniprot id: W0EUI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

880074:BARVI RS10670
gene id: 880074:BARVI_RS10670
uniprot id: W0EVU8
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

880074:BARVI RS03250
gene id: 880074:BARVI_RS03250
uniprot id: W0ER27
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

880074:BARVI RS12690
gene id: 880074:BARVI_RS12690
uniprot id: W0EWN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

880074:BARVI RS08730
gene id: 880074:BARVI_RS08730
uniprot id: W0EPX2
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS10510
gene id: 880074:BARVI_RS10510
uniprot id: W0EQU2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

880074:BARVI RS09660
gene id: 880074:BARVI_RS09660
uniprot id: W0ETX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

880074:BARVI RS11035
gene id: 880074:BARVI_RS11035
uniprot id: W0ER20
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS01370
gene id: 880074:BARVI_RS01370
uniprot id: W0ERB4
names: Similarity
messages: Belongs to the CvfB family.

880074:BARVI RS05050
gene id: 880074:BARVI_RS05050
uniprot id: W0ESG2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

880074:BARVI RS08000
gene id: 880074:BARVI_RS08000
uniprot id: W0ESQ8
names: Similarity
messages: Belongs to the asparagine synthetase family.

880074:BARVI RS10790
gene id: 880074:BARVI_RS10790
uniprot id: W0EVJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

880074:BARVI RS01005
gene id: 880074:BARVI_RS01005
uniprot id: W0ER58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

880074:BARVI RS09475
gene id: 880074:BARVI_RS09475
uniprot id: W0ETU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

880074:BARVI RS06715
gene id: 880074:BARVI_RS06715
uniprot id: W0ESK6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880074:BARVI RS08090
gene id: 880074:BARVI_RS08090
uniprot id: W0ETB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

880074:BARVI RS00520
gene id: 880074:BARVI_RS00520
uniprot id: W0EQU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

880074:BARVI RS10445
gene id: 880074:BARVI_RS10445
uniprot id: W0EVA6
names: Similarity
messages: Belongs to the UPF0758 family.

880074:BARVI RS04510
gene id: 880074:BARVI_RS04510
uniprot id: W0ESP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

880074:BARVI RS04885
gene id: 880074:BARVI_RS04885
uniprot id: W0ENB0
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS01395
gene id: 880074:BARVI_RS01395
uniprot id: W0ELT2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880074:BARVI RS09450
gene id: 880074:BARVI_RS09450
uniprot id: W0EUU0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

880074:BARVI RS00215
gene id: 880074:BARVI_RS00215
uniprot id: W0EKZ4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

880074:BARVI RS03325
gene id: 880074:BARVI_RS03325
uniprot id: W0ER36
names: Similarity
messages: Belongs to the peptidase S49 family.

880074:BARVI RS09655
gene id: 880074:BARVI_RS09655
uniprot id: W0EQG7
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

880074:BARVI RS01095
gene id: 880074:BARVI_RS01095
uniprot id: W0ER74
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

880074:BARVI RS10730
gene id: 880074:BARVI_RS10730
uniprot id: W0EVV7
names: Similarity
messages: Belongs to the peptidase M24B family.

880074:BARVI RS05965
gene id: 880074:BARVI_RS05965
uniprot id: W0ENM5
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

880074:BARVI RS00730
gene id: 880074:BARVI_RS00730
uniprot id: W0EL95
names: Similarity
messages: Belongs to the universal stress protein A family.

880074:BARVI RS09645
gene id: 880074:BARVI_RS09645
uniprot id: W0EQB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

880074:BARVI RS08975
gene id: 880074:BARVI_RS08975
uniprot id: W0EQ05
names: Similarity
messages: Belongs to the alkaline phosphatase family.

880074:BARVI RS04990
gene id: 880074:BARVI_RS04990
uniprot id: W0END0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

880074:BARVI RS06755
gene id: 880074:BARVI_RS06755
uniprot id: W0ETV1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

880074:BARVI RS10765
gene id: 880074:BARVI_RS10765
uniprot id: W0EQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

880074:BARVI RS00960
gene id: 880074:BARVI_RS00960
uniprot id: W0ELL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

880074:BARVI RS05645
gene id: 880074:BARVI_RS05645
uniprot id: W0ETD5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

880074:BARVI RS01555
gene id: 880074:BARVI_RS01555
uniprot id: W0ELP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

880074:BARVI RS04925
gene id: 880074:BARVI_RS04925
uniprot id: W0EN59
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

880074:BARVI RS10365
gene id: 880074:BARVI_RS10365
uniprot id: W0EV88
names: Similarity
messages: Belongs to the aldose epimerase family.

880074:BARVI RS02415
gene id: 880074:BARVI_RS02415
uniprot id: W0EVM2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

880074:BARVI RS08045
gene id: 880074:BARVI_RS08045
uniprot id: W0EU93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

880074:BARVI RS07700
gene id: 880074:BARVI_RS07700
uniprot id: W0EUE5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

880074:BARVI RS08100
gene id: 880074:BARVI_RS08100
uniprot id: W0EPN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

880074:BARVI RS05390
gene id: 880074:BARVI_RS05390
uniprot id: W0ENC6
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

880074:BARVI RS12745
gene id: 880074:BARVI_RS12745
uniprot id: W0EWQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

880074:BARVI RS06070
gene id: 880074:BARVI_RS06070
uniprot id: W0ESC0
names: Similarity
messages: Belongs to the IMPACT family.

880074:BARVI RS07855
gene id: 880074:BARVI_RS07855
uniprot id: W0EU72
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS01635
gene id: 880074:BARVI_RS01635
uniprot id: W0ERN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

880074:BARVI RS07635
gene id: 880074:BARVI_RS07635
uniprot id: W0EPM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

880074:BARVI RS06505
gene id: 880074:BARVI_RS06505
uniprot id: W0ETQ9
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS08070
gene id: 880074:BARVI_RS08070
uniprot id: W0EU97
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

880074:BARVI RS01785
gene id: 880074:BARVI_RS01785
uniprot id: W0ERH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

880074:BARVI RS05235
gene id: 880074:BARVI_RS05235
uniprot id: W0ES02
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

880074:BARVI RS12665
gene id: 880074:BARVI_RS12665
uniprot id: W0ERU6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880074:BARVI RS00490
gene id: 880074:BARVI_RS00490
uniprot id: W0EPV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

880074:BARVI RS07085
gene id: 880074:BARVI_RS07085
uniprot id: W0EPB5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880074:BARVI RS10800
gene id: 880074:BARVI_RS10800
uniprot id: W0EVW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

880074:BARVI RS09605
gene id: 880074:BARVI_RS09605
uniprot id: W0EQA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

880074:BARVI RS07080
gene id: 880074:BARVI_RS07080
uniprot id: W0EU12
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

880074:BARVI RS00455
gene id: 880074:BARVI_RS00455
uniprot id: W0ER31
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880074:BARVI RS00220
gene id: 880074:BARVI_RS00220
uniprot id: W0EQY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

880074:BARVI RS09920
gene id: 880074:BARVI_RS09920
uniprot id: W0EVD0
names: Similarity
messages: Belongs to the XseB family.

880074:BARVI RS10640
gene id: 880074:BARVI_RS10640
uniprot id: W0EQW5
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

880074:BARVI RS07685
gene id: 880074:BARVI_RS07685
uniprot id: W0EU51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

880074:BARVI RS04290
gene id: 880074:BARVI_RS04290
uniprot id: W0EN30
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

880074:BARVI RS04675
gene id: 880074:BARVI_RS04675
uniprot id: W0ERS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

880074:BARVI RS07210
gene id: 880074:BARVI_RS07210
uniprot id: W0EPD7
names: Similarity
messages: Belongs to the SusD family.

880074:BARVI RS09245
gene id: 880074:BARVI_RS09245
uniprot id: W0EQ97
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

880074:BARVI RS05315
gene id: 880074:BARVI_RS05315
uniprot id: W0ET86
names: Similarity
messages: Belongs to the transketolase family.

880074:BARVI RS00670
gene id: 880074:BARVI_RS00670
uniprot id: W0EQX3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

880074:BARVI RS01245
gene id: 880074:BARVI_RS01245
uniprot id: W0EQB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

880074:BARVI RS11255
gene id: 880074:BARVI_RS11255
uniprot id: W0EVQ5
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS06090
gene id: 880074:BARVI_RS06090
uniprot id: W0ENV2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

880074:BARVI RS08170
gene id: 880074:BARVI_RS08170
uniprot id: W0EUB2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

880074:BARVI RS08510
gene id: 880074:BARVI_RS08510
uniprot id: W0EUF0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

880074:BARVI RS09540
gene id: 880074:BARVI_RS09540
uniprot id: W0ETV6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

880074:BARVI RS05665
gene id: 880074:BARVI_RS05665
uniprot id: W0ENH1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

880074:BARVI RS07265
gene id: 880074:BARVI_RS07265
uniprot id: W0EPE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

880074:BARVI RS03080
gene id: 880074:BARVI_RS03080
uniprot id: W0ES09
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880074:BARVI RS03190
gene id: 880074:BARVI_RS03190
uniprot id: W0EMJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

880074:BARVI RS09445
gene id: 880074:BARVI_RS09445
uniprot id: W0ETU1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

880074:BARVI RS00295
gene id: 880074:BARVI_RS00295
uniprot id: W0ER06
names: Similarity
messages: Belongs to the glutamate synthase family.

880074:BARVI RS03980
gene id: 880074:BARVI_RS03980
uniprot id: W0ESD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

880074:BARVI RS09125
gene id: 880074:BARVI_RS09125
uniprot id: W0EV07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

880074:BARVI RS09415
gene id: 880074:BARVI_RS09415
uniprot id: W0ETT6
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS03230
gene id: 880074:BARVI_RS03230
uniprot id: W0EMC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

880074:BARVI RS10705
gene id: 880074:BARVI_RS10705
uniprot id: W0ER15
names: Similarity
messages: Belongs to the Skp family.

880074:BARVI RS00855
gene id: 880074:BARVI_RS00855
uniprot id: W0ELH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

880074:BARVI RS11300
gene id: 880074:BARVI_RS11300
uniprot id: W0ER96
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

880074:BARVI RS01790
gene id: 880074:BARVI_RS01790
uniprot id: W0ELS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

880074:BARVI RS11495
gene id: 880074:BARVI_RS11495
uniprot id: W0EVS8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

880074:BARVI RS06125
gene id: 880074:BARVI_RS06125
uniprot id: W0ESC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

880074:BARVI RS01405
gene id: 880074:BARVI_RS01405
uniprot id: W0EQD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

880074:BARVI RS00315
gene id: 880074:BARVI_RS00315
uniprot id: W0EL18
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS02980
gene id: 880074:BARVI_RS02980
uniprot id: W0ERZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

880074:BARVI RS06150
gene id: 880074:BARVI_RS06150
uniprot id: W0ENQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

880074:BARVI RS05845
gene id: 880074:BARVI_RS05845
uniprot id: W0ES88
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

880074:BARVI RS09380
gene id: 880074:BARVI_RS09380
uniprot id: W0EV42
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

880074:BARVI RS09580
gene id: 880074:BARVI_RS09580
uniprot id: W0EQA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

880074:BARVI RS08410
gene id: 880074:BARVI_RS08410
uniprot id: W0EUP8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880074:BARVI RS01775
gene id: 880074:BARVI_RS01775
uniprot id: W0ELZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

880074:BARVI RS05890
gene id: 880074:BARVI_RS05890
uniprot id: W0ENL1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880074:BARVI RS01240
gene id: 880074:BARVI_RS01240
uniprot id: W0ELQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

880074:BARVI RS04670
gene id: 880074:BARVI_RS04670
uniprot id: W0EN81
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

880074:BARVI RS04380
gene id: 880074:BARVI_RS04380
uniprot id: W0ESV5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

880074:BARVI RS09815
gene id: 880074:BARVI_RS09815
uniprot id: W0EV00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

880074:BARVI RS10270
gene id: 880074:BARVI_RS10270
uniprot id: W0EU83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

880074:BARVI RS11115
gene id: 880074:BARVI_RS11115
uniprot id: W0ER68
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

880074:BARVI RS02070
gene id: 880074:BARVI_RS02070
uniprot id: W0ERL0
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS01625
gene id: 880074:BARVI_RS01625
uniprot id: W0ERF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

880074:BARVI RS01530
gene id: 880074:BARVI_RS01530
uniprot id: W0ELN7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

880074:BARVI RS05625
gene id: 880074:BARVI_RS05625
uniprot id: W0ES58
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

880074:BARVI RS12490
gene id: 880074:BARVI_RS12490
uniprot id: W0ERR4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880074:BARVI RS00560
gene id: 880074:BARVI_RS00560
uniprot id: W0ER50
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

880074:BARVI RS05570
gene id: 880074:BARVI_RS05570
uniprot id: W0ET44
names: Similarity
messages: Belongs to the SAICAR synthetase family.

880074:BARVI RS07860
gene id: 880074:BARVI_RS07860
uniprot id: W0EPK8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

880074:BARVI RS09500
gene id: 880074:BARVI_RS09500
uniprot id: W0EV57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS12115
gene id: 880074:BARVI_RS12115
uniprot id: W0EWE9
names: Similarity
messages: Belongs to the type IA topoisomerase family.

880074:BARVI RS08120
gene id: 880074:BARVI_RS08120
uniprot id: W0EUA5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

880074:BARVI RS01355
gene id: 880074:BARVI_RS01355
uniprot id: W0ELS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

880074:BARVI RS00790
gene id: 880074:BARVI_RS00790
uniprot id: W0EQZ2
names: Similarity
messages: Belongs to the glutamine synthetase family.

880074:BARVI RS07335
gene id: 880074:BARVI_RS07335
uniprot id: W0ETW8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

880074:BARVI RS10470
gene id: 880074:BARVI_RS10470
uniprot id: W0EUC0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

880074:BARVI RS11190
gene id: 880074:BARVI_RS11190
uniprot id: W0ER76
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS10700
gene id: 880074:BARVI_RS10700
uniprot id: W0EVV2
names: Similarity
messages: Belongs to the Skp family.

880074:BARVI RS08060
gene id: 880074:BARVI_RS08060
uniprot id: W0EPT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

880074:BARVI RS08400
gene id: 880074:BARVI_RS08400
uniprot id: W0EUD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

880074:BARVI RS07525
gene id: 880074:BARVI_RS07525
uniprot id: W0ET30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

880074:BARVI RS09110
gene id: 880074:BARVI_RS09110
uniprot id: W0ETP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

880074:BARVI RS01490
gene id: 880074:BARVI_RS01490
uniprot id: W0EQE6
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS03345
gene id: 880074:BARVI_RS03345
uniprot id: W0EML7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

880074:BARVI RS02715
gene id: 880074:BARVI_RS02715
uniprot id: W0EMB8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

880074:BARVI RS01080
gene id: 880074:BARVI_RS01080
uniprot id: W0ERG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

880074:BARVI RS00525
gene id: 880074:BARVI_RS00525
uniprot id: W0EL57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

880074:BARVI RS08015
gene id: 880074:BARVI_RS08015
uniprot id: W0ET99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

880074:BARVI RS08635
gene id: 880074:BARVI_RS08635
uniprot id: W0ETI8
names: Cofactor
messages: Binds 2 iron ions per subunit.

880074:BARVI RS00155
gene id: 880074:BARVI_RS00155
uniprot id: W0EKY3
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

880074:BARVI RS08830
gene id: 880074:BARVI_RS08830
uniprot id: W0EPY1
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

880074:BARVI RS05550
gene id: 880074:BARVI_RS05550
uniprot id: W0ENE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

880074:BARVI RS11925
gene id: 880074:BARVI_RS11925
uniprot id: W0EVX2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

880074:BARVI RS02775
gene id: 880074:BARVI_RS02775
uniprot id: W0EQX0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

880074:BARVI RS00565
gene id: 880074:BARVI_RS00565
uniprot id: W0ELD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

880074:BARVI RS09100
gene id: 880074:BARVI_RS09100
uniprot id: W0EV02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

880074:BARVI RS08135
gene id: 880074:BARVI_RS08135
uniprot id: W0EPU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

880074:BARVI RS10735
gene id: 880074:BARVI_RS10735
uniprot id: W0ER19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

880074:BARVI RS11265
gene id: 880074:BARVI_RS11265
uniprot id: W0ER47
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

880074:BARVI RS00305
gene id: 880074:BARVI_RS00305
uniprot id: W0EPR7
names: Similarity
messages: Belongs to the asparagine synthetase family.

880074:BARVI RS03340
gene id: 880074:BARVI_RS03340
uniprot id: W0ESC6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

880074:BARVI RS12590
gene id: 880074:BARVI_RS12590
uniprot id: W0EWM4
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

880074:BARVI RS10990
gene id: 880074:BARVI_RS10990
uniprot id: W0EXX3
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

880074:BARVI RS10960
gene id: 880074:BARVI_RS10960
uniprot id: W0ER48
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

880074:BARVI RS09590
gene id: 880074:BARVI_RS09590
uniprot id: W0EQF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

880074:BARVI RS12645
gene id: 880074:BARVI_RS12645
uniprot id: W0EWA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

880074:BARVI RS05175
gene id: 880074:BARVI_RS05175
uniprot id: W0ESY6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

880074:BARVI RS00240
gene id: 880074:BARVI_RS00240
uniprot id: W0EL00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS08855
gene id: 880074:BARVI_RS08855
uniprot id: W0EPY6
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS06410
gene id: 880074:BARVI_RS06410
uniprot id: W0ETH7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

880074:BARVI RS06985
gene id: 880074:BARVI_RS06985
uniprot id: W0EP93
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

880074:BARVI RS08775
gene id: 880074:BARVI_RS08775
uniprot id: W0ETK1
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

880074:BARVI RS00610
gene id: 880074:BARVI_RS00610
uniprot id: W0EL74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

880074:BARVI RS04835
gene id: 880074:BARVI_RS04835
uniprot id: W0ESF2
names: Similarity
messages: Belongs to the SusD family.

880074:BARVI RS03055
gene id: 880074:BARVI_RS03055
uniprot id: W0ES04
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

880074:BARVI RS03365
gene id: 880074:BARVI_RS03365
uniprot id: W0EMF0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

880074:BARVI RS08065
gene id: 880074:BARVI_RS08065
uniprot id: W0ETA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

880074:BARVI RS00465
gene id: 880074:BARVI_RS00465
uniprot id: W0EPU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

880074:BARVI RS01620
gene id: 880074:BARVI_RS01620
uniprot id: W0EQG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

880074:BARVI RS00005
gene id: 880074:BARVI_RS00005
uniprot id: W0EPL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

880074:BARVI RS08980
gene id: 880074:BARVI_RS08980
uniprot id: W0EUY2
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

880074:BARVI RS07850
gene id: 880074:BARVI_RS07850
uniprot id: W0ET77
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS01630
gene id: 880074:BARVI_RS01630
uniprot id: W0ELQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

880074:BARVI RS05840
gene id: 880074:BARVI_RS05840
uniprot id: W0ENQ4
names: Similarity
messages: Belongs to the threonine synthase family.

880074:BARVI RS05340
gene id: 880074:BARVI_RS05340
uniprot id: W0ET91
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

880074:BARVI RS10845
gene id: 880074:BARVI_RS10845
uniprot id: W0EQZ1
names: Similarity
messages: Belongs to the DprA/Smf family.

880074:BARVI RS06430
gene id: 880074:BARVI_RS06430
uniprot id: W0ESG6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880074:BARVI RS00785
gene id: 880074:BARVI_RS00785
uniprot id: W0EQ04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

880074:BARVI RS08595
gene id: 880074:BARVI_RS08595
uniprot id: W0EPV5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880074:BARVI RS01550
gene id: 880074:BARVI_RS01550
uniprot id: W0ERD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

880074:BARVI RS09080
gene id: 880074:BARVI_RS09080
uniprot id: W0ETP2
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS05150
gene id: 880074:BARVI_RS05150
uniprot id: W0ET61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

880074:BARVI RS03490
gene id: 880074:BARVI_RS03490
uniprot id: W0ESE4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

880074:BARVI RS12485
gene id: 880074:BARVI_RS12485
uniprot id: W0EWK5
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS02065
gene id: 880074:BARVI_RS02065
uniprot id: W0EQN0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

880074:BARVI RS05870
gene id: 880074:BARVI_RS05870
uniprot id: W0ENR0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

880074:BARVI RS04375
gene id: 880074:BARVI_RS04375
uniprot id: W0EMY9
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

880074:BARVI RS07690
gene id: 880074:BARVI_RS07690
uniprot id: W0EPI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Membrane

880074:BARVI RS08835
gene id: 880074:BARVI_RS08835
uniprot id: W0EUV9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

880074:BARVI RS03265
gene id: 880074:BARVI_RS03265
uniprot id: W0ESB7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS00600
gene id: 880074:BARVI_RS00600
uniprot id: W0EPX3
names: Similarity
messages: Belongs to the aldose epimerase family.

880074:BARVI RS08780
gene id: 880074:BARVI_RS08780
uniprot id: W0EUI5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

880074:BARVI RS00800
gene id: 880074:BARVI_RS00800
uniprot id: W0ER94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

880074:BARVI RS06875
gene id: 880074:BARVI_RS06875
uniprot id: W0ETN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

880074:BARVI RS01125
gene id: 880074:BARVI_RS01125
uniprot id: W0ER80
names: Similarity
messages: Belongs to the RecJ family.

880074:BARVI RS11170
gene id: 880074:BARVI_RS11170
uniprot id: W0EVP4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880074:BARVI RS07105
gene id: 880074:BARVI_RS07105
uniprot id: W0EU17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

880074:BARVI RS08580
gene id: 880074:BARVI_RS08580
uniprot id: W0EPZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

880074:BARVI RS12345
gene id: 880074:BARVI_RS12345
uniprot id: W0ERJ8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

880074:BARVI RS08845
gene id: 880074:BARVI_RS08845
uniprot id: W0ETL0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

880074:BARVI RS08230
gene id: 880074:BARVI_RS08230
uniprot id: W0EXC6
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS00175
gene id: 880074:BARVI_RS00175
uniprot id: W0EPN9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

880074:BARVI RS00935
gene id: 880074:BARVI_RS00935
uniprot id: W0EQ43
names: Similarity
messages: Belongs to the UPF0047 family.

880074:BARVI RS00840
gene id: 880074:BARVI_RS00840
uniprot id: W0ELB2
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

880074:BARVI RS08140
gene id: 880074:BARVI_RS08140
uniprot id: W0ETC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

880074:BARVI RS08200
gene id: 880074:BARVI_RS08200
uniprot id: W0EPQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

880074:BARVI RS08005
gene id: 880074:BARVI_RS08005
uniprot id: W0EPS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

880074:BARVI RS00410
gene id: 880074:BARVI_RS00410
uniprot id: W0EL35
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

880074:BARVI RS10645
gene id: 880074:BARVI_RS10645
uniprot id: W0EVU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

880074:BARVI RS07095
gene id: 880074:BARVI_RS07095
uniprot id: W0ETS6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

880074:BARVI RS03255
gene id: 880074:BARVI_RS03255
uniprot id: W0ES36
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

880074:BARVI RS00270
gene id: 880074:BARVI_RS00270
uniprot id: W0ER01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

880074:BARVI RS05815
gene id: 880074:BARVI_RS05815
uniprot id: W0ENP9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

880074:BARVI RS06425
gene id: 880074:BARVI_RS06425
uniprot id: W0EP01
names: Similarity
messages: Belongs to the AlaDH/PNT family.

880074:BARVI RS11440
gene id: 880074:BARVI_RS11440
uniprot id: W0ERB3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880074:BARVI RS09840
gene id: 880074:BARVI_RS09840
uniprot id: W0EU06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

880074:BARVI RS06565
gene id: 880074:BARVI_RS06565
uniprot id: W0ETJ6
names: Similarity
messages: Belongs to the peptidase M16 family.

880074:BARVI RS01110
gene id: 880074:BARVI_RS01110
uniprot id: W0ERG9
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS08215
gene id: 880074:BARVI_RS08215
uniprot id: W0ETC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

880074:BARVI RS02830
gene id: 880074:BARVI_RS02830
uniprot id: W0ERX2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

880074:BARVI RS02945
gene id: 880074:BARVI_RS02945
uniprot id: W0EQY5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

880074:BARVI RS09795
gene id: 880074:BARVI_RS09795
uniprot id: W0EQJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

880074:BARVI RS04300
gene id: 880074:BARVI_RS04300
uniprot id: W0ESL4
names: Similarity
messages: Belongs to the peptidase C69 family.

880074:BARVI RS07055
gene id: 880074:BARVI_RS07055
uniprot id: W0EU05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

880074:BARVI RS08375
gene id: 880074:BARVI_RS08375
uniprot id: W0EUD4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880074:BARVI RS09165
gene id: 880074:BARVI_RS09165
uniprot id: W0EUP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

880074:BARVI RS10340
gene id: 880074:BARVI_RS10340
uniprot id: W0EQP5
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

880074:BARVI RS08110
gene id: 880074:BARVI_RS08110
uniprot id: W0EPT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

880074:BARVI RS01235
gene id: 880074:BARVI_RS01235
uniprot id: W0ERI3
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS01255
gene id: 880074:BARVI_RS01255
uniprot id: W0ELK3
names: Similarity
messages: Belongs to the Fur family.

880074:BARVI RS09025
gene id: 880074:BARVI_RS09025
uniprot id: W0ETN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

880074:BARVI RS05025
gene id: 880074:BARVI_RS05025
uniprot id: W0END2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

880074:BARVI RS02890
gene id: 880074:BARVI_RS02890
uniprot id: W0EQY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

880074:BARVI RS01280
gene id: 880074:BARVI_RS01280
uniprot id: W0ELK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

880074:BARVI RS00435
gene id: 880074:BARVI_RS00435
uniprot id: W0EQT4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS02930
gene id: 880074:BARVI_RS02930
uniprot id: W0EM85
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

880074:BARVI RS08890
gene id: 880074:BARVI_RS08890
uniprot id: W0EPZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS09335
gene id: 880074:BARVI_RS09335
uniprot id: W0EV38
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

880074:BARVI RS12430
gene id: 880074:BARVI_RS12430
uniprot id: W0EWJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

880074:BARVI RS04545
gene id: 880074:BARVI_RS04545
uniprot id: W0EN08
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

880074:BARVI RS05995
gene id: 880074:BARVI_RS05995
uniprot id: W0ENN0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

880074:BARVI RS00605
gene id: 880074:BARVI_RS00605
uniprot id: W0EQW4
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

880074:BARVI RS09140
gene id: 880074:BARVI_RS09140
uniprot id: W0EUP3
names: Similarity
messages: Belongs to the ParB family.

880074:BARVI RS05075
gene id: 880074:BARVI_RS05075
uniprot id: W0ESX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

880074:BARVI RS09600
gene id: 880074:BARVI_RS09600
uniprot id: W0EUW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

880074:BARVI RS02835
gene id: 880074:BARVI_RS02835
uniprot id: W0EM79
names: Similarity
messages: Belongs to the aldose epimerase family.

880074:BARVI RS03970
gene id: 880074:BARVI_RS03970
uniprot id: W0ERC6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS12540
gene id: 880074:BARVI_RS12540
uniprot id: W0EWL5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

880074:BARVI RS05285
gene id: 880074:BARVI_RS05285
uniprot id: W0ET82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

880074:BARVI RS00265
gene id: 880074:BARVI_RS00265
uniprot id: W0EL07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

880074:BARVI RS06360
gene id: 880074:BARVI_RS06360
uniprot id: W0ENZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

880074:BARVI RS09425
gene id: 880074:BARVI_RS09425
uniprot id: W0EQ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

880074:BARVI RS05360
gene id: 880074:BARVI_RS05360
uniprot id: W0EW38
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

880074:BARVI RS12550
gene id: 880074:BARVI_RS12550
uniprot id: W0EV85
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

880074:BARVI RS02040
gene id: 880074:BARVI_RS02040
uniprot id: W0ERK5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

880074:BARVI RS06710
gene id: 880074:BARVI_RS06710
uniprot id: W0EP45
names: Function
names: Similarity
messages: A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3'.
messages: Belongs to the DpnII type II restriction endonuclease family.

880074:BARVI RS05820
gene id: 880074:BARVI_RS05820
uniprot id: W0EM79
names: Similarity
messages: Belongs to the aldose epimerase family.

880074:BARVI RS10780
gene id: 880074:BARVI_RS10780
uniprot id: W0ER23
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

880074:BARVI RS06170
gene id: 880074:BARVI_RS06170
uniprot id: W0ETE7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

880074:BARVI RS02940
gene id: 880074:BARVI_RS02940
uniprot id: W0EMF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

880074:BARVI RS08130
gene id: 880074:BARVI_RS08130
uniprot id: W0EUL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

880074:BARVI RS04430
gene id: 880074:BARVI_RS04430
uniprot id: W0EN50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

880074:BARVI RS02770
gene id: 880074:BARVI_RS02770
uniprot id: W0EMD0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

880074:BARVI RS02355
gene id: 880074:BARVI_RS02355
uniprot id: W0ERZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

880074:BARVI RS01185
gene id: 880074:BARVI_RS01185
uniprot id: W0ER88
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

880074:BARVI RS12100
gene id: 880074:BARVI_RS12100
uniprot id: W0EV24
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

880074:BARVI RS05135
gene id: 880074:BARVI_RS05135
uniprot id: W0ERY8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

880074:BARVI RS05805
gene id: 880074:BARVI_RS05805
uniprot id: W0ENJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

880074:BARVI RS05850
gene id: 880074:BARVI_RS05850
uniprot id: W0ET92
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

880074:BARVI RS00510
gene id: 880074:BARVI_RS00510
uniprot id: W0ELC2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS05565
gene id: 880074:BARVI_RS05565
uniprot id: W0ES49
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

880074:BARVI RS02820
gene id: 880074:BARVI_RS02820
uniprot id: W0EX34
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

880074:BARVI RS04000
gene id: 880074:BARVI_RS04000
uniprot id: W0EMV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS00145
gene id: 880074:BARVI_RS00145
uniprot id: W0EQN5
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

880074:BARVI RS10375
gene id: 880074:BARVI_RS10375
uniprot id: W0EQQ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

880074:BARVI RS07450
gene id: 880074:BARVI_RS07450
uniprot id: W0EPF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

880074:BARVI RS08050
gene id: 880074:BARVI_RS08050
uniprot id: W0EPN1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

880074:BARVI RS01020
gene id: 880074:BARVI_RS01020
uniprot id: W0ELM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

880074:BARVI RS12325
gene id: 880074:BARVI_RS12325
uniprot id: W0EWI4
names: Similarity
messages: Belongs to the CapA family.

880074:BARVI RS09315
gene id: 880074:BARVI_RS09315
uniprot id: W0EQA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

880074:BARVI RS12460
gene id: 880074:BARVI_RS12460
uniprot id: W0ERQ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

880074:BARVI RS09085
gene id: 880074:BARVI_RS09085
uniprot id: W0EUN4
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

880074:BARVI RS05505
gene id: 880074:BARVI_RS05505
uniprot id: W0ENE6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

880074:BARVI RS02850
gene id: 880074:BARVI_RS02850
uniprot id: W0EME0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

880074:BARVI RS02085
gene id: 880074:BARVI_RS02085
uniprot id: W0EM38
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

880074:BARVI RS06920
gene id: 880074:BARVI_RS06920
uniprot id: W0ETY0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS05895
gene id: 880074:BARVI_RS05895
uniprot id: W0ETH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

880074:BARVI RS01380
gene id: 880074:BARVI_RS01380
uniprot id: W0ELL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

880074:BARVI RS08695
gene id: 880074:BARVI_RS08695
uniprot id: W0EPW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

880074:BARVI RS05145
gene id: 880074:BARVI_RS05145
uniprot id: W0EN89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

880074:BARVI RS10605
gene id: 880074:BARVI_RS10605
uniprot id: W0EVU0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

880074:BARVI RS12415
gene id: 880074:BARVI_RS12415
uniprot id: W0ERP6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

880074:BARVI RS12535
gene id: 880074:BARVI_RS12535
uniprot id: W0ERM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

880074:BARVI RS03890
gene id: 880074:BARVI_RS03890
uniprot id: W0ESC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

880074:BARVI RS09005
gene id: 880074:BARVI_RS09005
uniprot id: W0EUY7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

880074:BARVI RS06405
gene id: 880074:BARVI_RS06405
uniprot id: W0ESG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

880074:BARVI RS03700
gene id: 880074:BARVI_RS03700
uniprot id: W0ER95
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

880074:BARVI RS09325
gene id: 880074:BARVI_RS09325
uniprot id: W0EUS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880074:BARVI RS07625
gene id: 880074:BARVI_RS07625
uniprot id: W0EPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

880074:BARVI RS05015
gene id: 880074:BARVI_RS05015
uniprot id: W0ET41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

880074:BARVI RS11030
gene id: 880074:BARVI_RS11030
uniprot id: W0EVM6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

880074:BARVI RS05220
gene id: 880074:BARVI_RS05220
uniprot id: W0ET71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

880074:BARVI RS07100
gene id: 880074:BARVI_RS07100
uniprot id: W0EP68
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

880074:BARVI RS00740
gene id: 880074:BARVI_RS00740
uniprot id: W0ELF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

880074:BARVI RS00780
gene id: 880074:BARVI_RS00780
uniprot id: W0ELG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS05345
gene id: 880074:BARVI_RS05345
uniprot id: W0ENH8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

880074:BARVI RS03115
gene id: 880074:BARVI_RS03115
uniprot id: W0ES96
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS05720
gene id: 880074:BARVI_RS05720
uniprot id: W0ETE9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

880074:BARVI RS09330
gene id: 880074:BARVI_RS09330
uniprot id: W0EQ61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

880074:BARVI RS07985
gene id: 880074:BARVI_RS07985
uniprot id: W0EPM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

880074:BARVI RS01220
gene id: 880074:BARVI_RS01220
uniprot id: W0ER93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

880074:BARVI RS10955
gene id: 880074:BARVI_RS10955
uniprot id: W0EVZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

880074:BARVI RS09170
gene id: 880074:BARVI_RS09170
uniprot id: W0EQ39
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS10865
gene id: 880074:BARVI_RS10865
uniprot id: W0EVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

880074:BARVI RS04260
gene id: 880074:BARVI_RS04260
uniprot id: W0ESS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

880074:BARVI RS08575
gene id: 880074:BARVI_RS08575
uniprot id: W0EUS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

880074:BARVI RS08325
gene id: 880074:BARVI_RS08325
uniprot id: W0EPR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS05200
gene id: 880074:BARVI_RS05200
uniprot id: W0ENF7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

880074:BARVI RS10320
gene id: 880074:BARVI_RS10320
uniprot id: W0EQT7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880074:BARVI RS09775
gene id: 880074:BARVI_RS09775
uniprot id: W0EUZ5
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS01440
gene id: 880074:BARVI_RS01440
uniprot id: W0ERC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

880074:BARVI RS04800
gene id: 880074:BARVI_RS04800
uniprot id: W0EST2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

880074:BARVI RS11250
gene id: 880074:BARVI_RS11250
uniprot id: W0EUR5
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS08210
gene id: 880074:BARVI_RS08210
uniprot id: W0EPV4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

880074:BARVI RS07370
gene id: 880074:BARVI_RS07370
uniprot id: W0ETX3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

880074:BARVI RS08125
gene id: 880074:BARVI_RS08125
uniprot id: W0EPP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

880074:BARVI RS10655
gene id: 880074:BARVI_RS10655
uniprot id: W0EUH3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS13510
gene id: 880074:BARVI_RS13510
uniprot id: W0EN12
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

880074:BARVI RS01780
gene id: 880074:BARVI_RS01780
uniprot id: W0EQI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

880074:BARVI RS00080
gene id: 880074:BARVI_RS00080
uniprot id: W0EPM3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880074:BARVI RS07290
gene id: 880074:BARVI_RS07290
uniprot id: W0EPF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

880074:BARVI RS01475
gene id: 880074:BARVI_RS01475
uniprot id: W0ERL3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

880074:BARVI RS06175
gene id: 880074:BARVI_RS06175
uniprot id: W0ENR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

880074:BARVI RS03785
gene id: 880074:BARVI_RS03785
uniprot id: W0ESI9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

880074:BARVI RS02655
gene id: 880074:BARVI_RS02655
uniprot id: W0ES34
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880074:BARVI RS07270
gene id: 880074:BARVI_RS07270
uniprot id: W0ESV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

880074:BARVI RS08880
gene id: 880074:BARVI_RS08880
uniprot id: W0EUJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS08155
gene id: 880074:BARVI_RS08155
uniprot id: W0EUL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

880074:BARVI RS01855
gene id: 880074:BARVI_RS01855
uniprot id: W0ERS3
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

880074:BARVI RS10965
gene id: 880074:BARVI_RS10965
uniprot id: W0EUM2
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

880074:BARVI RS01845
gene id: 880074:BARVI_RS01845
uniprot id: W0ERI2
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

880074:BARVI RS06095
gene id: 880074:BARVI_RS06095
uniprot id: W0ESC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

880074:BARVI RS10795
gene id: 880074:BARVI_RS10795
uniprot id: W0EQY6
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

880074:BARVI RS07320
gene id: 880074:BARVI_RS07320
uniprot id: W0EPF5
names: Similarity
messages: Belongs to the peptidase S26 family.

880074:BARVI RS05770
gene id: 880074:BARVI_RS05770
uniprot id: W0ES77
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS02600
gene id: 880074:BARVI_RS02600
uniprot id: W0EMA0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

880074:BARVI RS12710
gene id: 880074:BARVI_RS12710
uniprot id: W0ERQ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

880074:BARVI RS06075
gene id: 880074:BARVI_RS06075
uniprot id: W0ETD3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

880074:BARVI RS07325
gene id: 880074:BARVI_RS07325
uniprot id: W0ESM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

880074:BARVI RS10475
gene id: 880074:BARVI_RS10475
uniprot id: W0EVB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

880074:BARVI RS05465
gene id: 880074:BARVI_RS05465
uniprot id: W0ENJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

880074:BARVI RS09105
gene id: 880074:BARVI_RS09105
uniprot id: W0EQ68
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

880074:BARVI RS12330
gene id: 880074:BARVI_RS12330
uniprot id: W0ERN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

880074:BARVI RS02360
gene id: 880074:BARVI_RS02360
uniprot id: W0EM77
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

880074:BARVI RS09570
gene id: 880074:BARVI_RS09570
uniprot id: W0ETW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

880074:BARVI RS08930
gene id: 880074:BARVI_RS08930
uniprot id: W0EUX3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

880074:BARVI RS08525
gene id: 880074:BARVI_RS08525
uniprot id: W0EPY9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

880074:BARVI RS04055
gene id: 880074:BARVI_RS04055
uniprot id: W0EMQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

880074:BARVI RS07225
gene id: 880074:BARVI_RS07225
uniprot id: W0EP92
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880074:BARVI RS00825
gene id: 880074:BARVI_RS00825
uniprot id: W0ELG7
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

880074:BARVI RS02740
gene id: 880074:BARVI_RS02740
uniprot id: W0EMC4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

880074:BARVI RS01290
gene id: 880074:BARVI_RS01290
uniprot id: W0ELS0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

880074:BARVI RS08205
gene id: 880074:BARVI_RS08205
uniprot id: W0EUM0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

880074:BARVI RS08035
gene id: 880074:BARVI_RS08035
uniprot id: W0EPS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

880074:BARVI RS04205
gene id: 880074:BARVI_RS04205
uniprot id: W0ERG2
names: Similarity
messages: Belongs to the fabD family.

880074:BARVI RS05385
gene id: 880074:BARVI_RS05385
uniprot id: W0ET13
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

880074:BARVI RS08710
gene id: 880074:BARVI_RS08710
uniprot id: W0EQ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

880074:BARVI RS01180
gene id: 880074:BARVI_RS01180
uniprot id: W0EQA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

880074:BARVI RS09880
gene id: 880074:BARVI_RS09880
uniprot id: W0EV09
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880074:BARVI RS05300
gene id: 880074:BARVI_RS05300
uniprot id: W0ET01
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

880074:BARVI RS08105
gene id: 880074:BARVI_RS08105
uniprot id: W0EUK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

880074:BARVI RS01975
gene id: 880074:BARVI_RS01975
uniprot id: W0EQL6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880074:BARVI RS12315
gene id: 880074:BARVI_RS12315
uniprot id: W0EW46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

880074:BARVI RS05705
gene id: 880074:BARVI_RS05705
uniprot id: W0ES71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

880074:BARVI RS03395
gene id: 880074:BARVI_RS03395
uniprot id: W0EMF5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS07480
gene id: 880074:BARVI_RS07480
uniprot id: W0EPG4
names: Similarity
messages: Belongs to the LOG family.

880074:BARVI RS12755
gene id: 880074:BARVI_RS12755
uniprot id: W0EWR7
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS09710
gene id: 880074:BARVI_RS09710
uniprot id: W0ETY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

880074:BARVI RS01535
gene id: 880074:BARVI_RS01535
uniprot id: W0ERM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

880074:BARVI RS09040
gene id: 880074:BARVI_RS09040
uniprot id: W0EUZ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

880074:BARVI RS04440
gene id: 880074:BARVI_RS04440
uniprot id: W0ESN4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

880074:BARVI RS01505
gene id: 880074:BARVI_RS01505
uniprot id: W0ELN2
names: Similarity
messages: Belongs to the type IA topoisomerase family.

880074:BARVI RS03330
gene id: 880074:BARVI_RS03330
uniprot id: W0ES47
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

880074:BARVI RS00530
gene id: 880074:BARVI_RS00530
uniprot id: W0ER46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

880074:BARVI RS00335
gene id: 880074:BARVI_RS00335
uniprot id: W0EQS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

880074:BARVI RS09780
gene id: 880074:BARVI_RS09780
uniprot id: W0EQE3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

880074:BARVI RS09300
gene id: 880074:BARVI_RS09300
uniprot id: W0EUR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

880074:BARVI RS10985
gene id: 880074:BARVI_RS10985
uniprot id: W0ER51
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

880074:BARVI RS01465
gene id: 880074:BARVI_RS01465
uniprot id: W0ERC7
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

880074:BARVI RS04940
gene id: 880074:BARVI_RS04940
uniprot id: W0ERW1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS10810
gene id: 880074:BARVI_RS10810
uniprot id: W0EUJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

880074:BARVI RS03170
gene id: 880074:BARVI_RS03170
uniprot id: W0ER18
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

880074:BARVI RS01795
gene id: 880074:BARVI_RS01795
uniprot id: W0ERR3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

880074:BARVI RS08080
gene id: 880074:BARVI_RS08080
uniprot id: W0EUK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

880074:BARVI RS06500
gene id: 880074:BARVI_RS06500
uniprot id: W0ENV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS00615
gene id: 880074:BARVI_RS00615
uniprot id: W0ER62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

880074:BARVI RS11500
gene id: 880074:BARVI_RS11500
uniprot id: W0ER79
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

880074:BARVI RS11160
gene id: 880074:BARVI_RS11160
uniprot id: W0EUQ0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

880074:BARVI RS10785
gene id: 880074:BARVI_RS10785
uniprot id: W0EUJ1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

880074:BARVI RS04655
gene id: 880074:BARVI_RS04655
uniprot id: W0ESR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

880074:BARVI RS07175
gene id: 880074:BARVI_RS07175
uniprot id: W0EPD1
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

880074:BARVI RS02075
gene id: 880074:BARVI_RS02075
uniprot id: W0ELW6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

880074:BARVI RS10805
gene id: 880074:BARVI_RS10805
uniprot id: W0ER26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

880074:BARVI RS02915
gene id: 880074:BARVI_RS02915
uniprot id: W0ERY2
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

880074:BARVI RS01900
gene id: 880074:BARVI_RS01900
uniprot id: W0EQK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

880074:BARVI RS01265
gene id: 880074:BARVI_RS01265
uniprot id: W0ELR4
names: Similarity
messages: Belongs to the aspartokinase family.

880074:BARVI RS11025
gene id: 880074:BARVI_RS11025
uniprot id: W0EUN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

880074:BARVI RS07555
gene id: 880074:BARVI_RS07555
uniprot id: W0EU31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

880074:BARVI RS04905
gene id: 880074:BARVI_RS04905
uniprot id: W0ET23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

880074:BARVI RS08570
gene id: 880074:BARVI_RS08570
uniprot id: W0EPV1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

880074:BARVI RS09595
gene id: 880074:BARVI_RS09595
uniprot id: W0ETW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

880074:BARVI RS12320
gene id: 880074:BARVI_RS12320
uniprot id: W0ERJ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880074:BARVI RS03015
gene id: 880074:BARVI_RS03015
uniprot id: W0EMG4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

880074:BARVI RS07550
gene id: 880074:BARVI_RS07550
uniprot id: W0ET37
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

880074:BARVI RS00165
gene id: 880074:BARVI_RS00165
uniprot id: W0EL56
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

880074:BARVI RS08990
gene id: 880074:BARVI_RS08990
uniprot id: W0ETM9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

880074:BARVI RS09960
gene id: 880074:BARVI_RS09960
uniprot id: W0EU27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

880074:BARVI RS06165
gene id: 880074:BARVI_RS06165
uniprot id: W0ESD2
names: Similarity
messages: Belongs to the peptidase S66 family.

880074:BARVI RS04870
gene id: 880074:BARVI_RS04870
uniprot id: W0EXD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

880074:BARVI RS00955
gene id: 880074:BARVI_RS00955
uniprot id: W0ERE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

880074:BARVI RS04700
gene id: 880074:BARVI_RS04700
uniprot id: W0EN85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

880074:BARVI RS09290
gene id: 880074:BARVI_RS09290
uniprot id: W0EQA1
names: Similarity
messages: Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.

880074:BARVI RS12350
gene id: 880074:BARVI_RS12350
uniprot id: W0EWI9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

880074:BARVI RS09130
gene id: 880074:BARVI_RS09130
uniprot id: W0EQ73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

880074:BARVI RS02370
gene id: 880074:BARVI_RS02370
uniprot id: W0ERQ6
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

880074:BARVI RS12310
gene id: 880074:BARVI_RS12310
uniprot id: W0EV51
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

880074:BARVI RS02625
gene id: 880074:BARVI_RS02625
uniprot id: W0ES31
names: Similarity
messages: Belongs to the ArsC family.

880074:BARVI RS08055
gene id: 880074:BARVI_RS08055
uniprot id: W0EUJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

880074:BARVI RS12405
gene id: 880074:BARVI_RS12405
uniprot id: W0ERK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

880074:BARVI RS08165
gene id: 880074:BARVI_RS08165
uniprot id: W0ETC7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

880074:BARVI RS07015
gene id: 880074:BARVI_RS07015
uniprot id: W0ESQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

880074:BARVI RS09695
gene id: 880074:BARVI_RS09695
uniprot id: W0EQC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880074:BARVI RS12760
gene id: 880074:BARVI_RS12760
uniprot id: W0EVC2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

880074:BARVI RS10880
gene id: 880074:BARVI_RS10880
uniprot id: W0ER38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

880074:BARVI RS06580
gene id: 880074:BARVI_RS06580
uniprot id: W0ENW8
names: Similarity
messages: Belongs to the LOG family.

880074:BARVI RS04865
gene id: 880074:BARVI_RS04865
uniprot id: W0EST9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

880074:BARVI RS00105
gene id: 880074:BARVI_RS00105
uniprot id: W0EPM9
names: Similarity
messages: Belongs to the SusD family.

880074:BARVI RS12730
gene id: 880074:BARVI_RS12730
uniprot id: W0EWB5
names: Similarity
messages: Belongs to the NusB family.

880074:BARVI RS06865
gene id: 880074:BARVI_RS06865
uniprot id: W0EP71
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

880074:BARVI RS01470
gene id: 880074:BARVI_RS01470
uniprot id: W0ELN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

880074:BARVI RS08680
gene id: 880074:BARVI_RS08680
uniprot id: W0ETJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

880074:BARVI RS04845
gene id: 880074:BARVI_RS04845
uniprot id: W0EN44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

880074:BARVI RS06725
gene id: 880074:BARVI_RS06725
uniprot id: W0ENZ6
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS06155
gene id: 880074:BARVI_RS06155
uniprot id: W0ETM0
names: Similarity
messages: Belongs to the SufE family.

880074:BARVI RS06485
gene id: 880074:BARVI_RS06485
uniprot id: W0EW77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Interacts with FtsZ.

880074:BARVI RS07890
gene id: 880074:BARVI_RS07890
uniprot id: W0EUG9
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

880074:BARVI RS00190
gene id: 880074:BARVI_RS00190
uniprot id: W0EQY4
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS07765
gene id: 880074:BARVI_RS07765
uniprot id: W0EPJ6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

880074:BARVI RS05520
gene id: 880074:BARVI_RS05520
uniprot id: W0ENK9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

880074:BARVI RS05650
gene id: 880074:BARVI_RS05650
uniprot id: W0ENM0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS07870
gene id: 880074:BARVI_RS07870
uniprot id: W0EPQ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS00665
gene id: 880074:BARVI_RS00665
uniprot id: W0EPY3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

880074:BARVI RS05860
gene id: 880074:BARVI_RS05860
uniprot id: W0ENK6
names: Similarity
messages: Belongs to the asparaginase 1 family.

880074:BARVI RS04165
gene id: 880074:BARVI_RS04165
uniprot id: W0ERF5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880074:BARVI RS02720
gene id: 880074:BARVI_RS02720
uniprot id: W0EQW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

880074:BARVI RS01160
gene id: 880074:BARVI_RS01160
uniprot id: W0ER85
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

880074:BARVI RS00985
gene id: 880074:BARVI_RS00985
uniprot id: W0ELL3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

880074:BARVI RS03000
gene id: 880074:BARVI_RS03000
uniprot id: W0ES79
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

880074:BARVI RS10665
gene id: 880074:BARVI_RS10665
uniprot id: W0EQX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

880074:BARVI RS08350
gene id: 880074:BARVI_RS08350
uniprot id: W0EUD0
names: Similarity
messages: Belongs to the UPF0145 family.

880074:BARVI RS04730
gene id: 880074:BARVI_RS04730
uniprot id: W0EN88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880074:BARVI RS04470
gene id: 880074:BARVI_RS04470
uniprot id: W0EN00
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

880074:BARVI RS07640
gene id: 880074:BARVI_RS07640
uniprot id: W0ET50
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

880074:BARVI RS05940
gene id: 880074:BARVI_RS05940
uniprot id: W0ENM1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

880074:BARVI RS07605
gene id: 880074:BARVI_RS07605
uniprot id: W0EUD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

880074:BARVI RS01090
gene id: 880074:BARVI_RS01090
uniprot id: W0EQ89
names: Similarity
messages: Belongs to the ClpA/ClpB family.

880074:BARVI RS09665
gene id: 880074:BARVI_RS09665
uniprot id: W0EUX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880074:BARVI RS03465
gene id: 880074:BARVI_RS03465
uniprot id: W0EWV0
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS07060
gene id: 880074:BARVI_RS07060
uniprot id: W0EPA9
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS03740
gene id: 880074:BARVI_RS03740
uniprot id: W0EMS5
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

880074:BARVI RS12705
gene id: 880074:BARVI_RS12705
uniprot id: W0EWB0
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

880074:BARVI RS03920
gene id: 880074:BARVI_RS03920
uniprot id: W0EMU5
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

880074:BARVI RS07505
gene id: 880074:BARVI_RS07505
uniprot id: W0EPG6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS06300
gene id: 880074:BARVI_RS06300
uniprot id: W0ETG6
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS08605
gene id: 880074:BARVI_RS08605
uniprot id: W0EQ01
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

880074:BARVI RS06370
gene id: 880074:BARVI_RS06370
uniprot id: W0ETH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880074:BARVI RS09940
gene id: 880074:BARVI_RS09940
uniprot id: W0EQG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS00040
gene id: 880074:BARVI_RS00040
uniprot id: W0EQL9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

880074:BARVI RS04450
gene id: 880074:BARVI_RS04450
uniprot id: W0ESW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

880074:BARVI RS12990
gene id: 880074:BARVI_RS12990
uniprot id: W0EUM5
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

880074:BARVI RS07250
gene id: 880074:BARVI_RS07250
uniprot id: W0ETV0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

880074:BARVI RS04660
gene id: 880074:BARVI_RS04660
uniprot id: W0EN20
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

880074:BARVI RS09515
gene id: 880074:BARVI_RS09515
uniprot id: W0ETV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

880074:BARVI RS06955
gene id: 880074:BARVI_RS06955
uniprot id: W0ETY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

880074:BARVI RS05000
gene id: 880074:BARVI_RS05000
uniprot id: W0ERW9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

880074:BARVI RS02630
gene id: 880074:BARVI_RS02630
uniprot id: W0EMA4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

880074:BARVI RS08600
gene id: 880074:BARVI_RS08600
uniprot id: W0EUS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

880074:BARVI RS05365
gene id: 880074:BARVI_RS05365
uniprot id: W0ENC1
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS11070
gene id: 880074:BARVI_RS11070
uniprot id: W0ER24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

880074:BARVI RS11450
gene id: 880074:BARVI_RS11450
uniprot id: W0EVS6
names: Similarity
messages: Belongs to the SusD family.

880074:BARVI RS08150
gene id: 880074:BARVI_RS08150
uniprot id: W0EPP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

880074:BARVI RS09630
gene id: 880074:BARVI_RS09630
uniprot id: W0EQG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880074:BARVI RS09585
gene id: 880074:BARVI_RS09585
uniprot id: W0EV72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

880074:BARVI RS05450
gene id: 880074:BARVI_RS05450
uniprot id: W0ET24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

880074:BARVI RS00495
gene id: 880074:BARVI_RS00495
uniprot id: W0EQU3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS06520
gene id: 880074:BARVI_RS06520
uniprot id: W0ETJ1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS08315
gene id: 880074:BARVI_RS08315
uniprot id: W0ETE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

880074:BARVI RS05710
gene id: 880074:BARVI_RS05710
uniprot id: W0ET68
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

880074:BARVI RS02030
gene id: 880074:BARVI_RS02030
uniprot id: W0EM28
names: Similarity
messages: Belongs to the DEAD box helicase family.

880074:BARVI RS11315
gene id: 880074:BARVI_RS11315
uniprot id: W0ER57
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

880074:BARVI RS00550
gene id: 880074:BARVI_RS00550
uniprot id: W0EQV3
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS01415
gene id: 880074:BARVI_RS01415
uniprot id: W0ELM3
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS12545
gene id: 880074:BARVI_RS12545
uniprot id: W0ERS4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

880074:BARVI RS07140
gene id: 880074:BARVI_RS07140
uniprot id: W0EU23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

880074:BARVI RS04050
gene id: 880074:BARVI_RS04050
uniprot id: W0ESE2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

880074:BARVI RS06970
gene id: 880074:BARVI_RS06970
uniprot id: W0ETQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

880074:BARVI RS12335
gene id: 880074:BARVI_RS12335
uniprot id: W0EV54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

880074:BARVI RS09000
gene id: 880074:BARVI_RS09000
uniprot id: W0EQ09
names: Similarity
messages: Belongs to the LacAB/RpiB family.

880074:BARVI RS09355
gene id: 880074:BARVI_RS09355
uniprot id: W0EUS7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

880074:BARVI RS04965
gene id: 880074:BARVI_RS04965
uniprot id: W0ESV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

880074:BARVI RS09210
gene id: 880074:BARVI_RS09210
uniprot id: W0EQ90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

880074:BARVI RS11920
gene id: 880074:BARVI_RS11920
uniprot id: W0EUZ3
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

880074:BARVI RS11020
gene id: 880074:BARVI_RS11020
uniprot id: W0ER54
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

880074:BARVI RS06760
gene id: 880074:BARVI_RS06760
uniprot id: W0EP55
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

880074:BARVI RS10970
gene id: 880074:BARVI_RS10970
uniprot id: W0EVL8
names: Similarity
messages: Belongs to the HypE family.

880074:BARVI RS13010
gene id: 880074:BARVI_RS13010
uniprot id: W0EUW8
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS01750
gene id: 880074:BARVI_RS01750
uniprot id: W0EQI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

880074:BARVI RS03075
gene id: 880074:BARVI_RS03075
uniprot id: W0ER03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

880074:BARVI RS07315
gene id: 880074:BARVI_RS07315
uniprot id: W0EU61
names: Similarity
messages: Belongs to the DapB family.

880074:BARVI RS06730
gene id: 880074:BARVI_RS06730
uniprot id: W0ETU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

880074:BARVI RS11420
gene id: 880074:BARVI_RS11420
uniprot id: W0EVS3
names: Similarity
messages: Belongs to the aldose epimerase family.

880074:BARVI RS05640
gene id: 880074:BARVI_RS05640
uniprot id: W0ENG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

880074:BARVI RS01805
gene id: 880074:BARVI_RS01805
uniprot id: W0ELZ8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

880074:BARVI RS07545
gene id: 880074:BARVI_RS07545
uniprot id: W0EPL3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

880074:BARVI RS07120
gene id: 880074:BARVI_RS07120
uniprot id: W0ETT0
names: Similarity
messages: Belongs to the peptidase S41A family.

880074:BARVI RS03995
gene id: 880074:BARVI_RS03995
uniprot id: W0ESL3
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

880074:BARVI RS04760
gene id: 880074:BARVI_RS04760
uniprot id: W0ET03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

880074:BARVI RS06560
gene id: 880074:BARVI_RS06560
uniprot id: W0ESI2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

880074:BARVI RS04695
gene id: 880074:BARVI_RS04695
uniprot id: W0ESZ7
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS03500
gene id: 880074:BARVI_RS03500
uniprot id: W0EMN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

880074:BARVI RS07835
gene id: 880074:BARVI_RS07835
uniprot id: W0EUG0
names: Similarity
messages: Belongs to the peptidase S41A family.

880074:BARVI RS12425
gene id: 880074:BARVI_RS12425
uniprot id: W0ERK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

880074:BARVI RS07020
gene id: 880074:BARVI_RS07020
uniprot id: W0ETR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

880074:BARVI RS00160
gene id: 880074:BARVI_RS00160
uniprot id: W0EQY0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

880074:BARVI RS03875
gene id: 880074:BARVI_RS03875
uniprot id: W0ESJ9
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS08355
gene id: 880074:BARVI_RS08355
uniprot id: W0EPR9
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

880074:BARVI RS10240
gene id: 880074:BARVI_RS10240
uniprot id: W0EU78
names: Similarity
messages: Belongs to the type IA topoisomerase family.

880074:BARVI RS12725
gene id: 880074:BARVI_RS12725
uniprot id: W0EVB8
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

880074:BARVI RS06220
gene id: 880074:BARVI_RS06220
uniprot id: W0ENX7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

880074:BARVI RS09765
gene id: 880074:BARVI_RS09765
uniprot id: W0EQI8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

880074:BARVI RS09915
gene id: 880074:BARVI_RS09915
uniprot id: W0EQG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880074:BARVI RS03475
gene id: 880074:BARVI_RS03475
uniprot id: W0EX79
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS09760
gene id: 880074:BARVI_RS09760
uniprot id: W0EVA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

880074:BARVI RS04295
gene id: 880074:BARVI_RS04295
uniprot id: W0ERK8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

880074:BARVI RS12635
gene id: 880074:BARVI_RS12635
uniprot id: W0ERU1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880074:BARVI RS02015
gene id: 880074:BARVI_RS02015
uniprot id: W0ERK1
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS00845
gene id: 880074:BARVI_RS00845
uniprot id: W0ER99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

880074:BARVI RS11610
gene id: 880074:BARVI_RS11610
uniprot id: W0ERD2
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

880074:BARVI RS08030
gene id: 880074:BARVI_RS08030
uniprot id: W0EUI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

880074:BARVI RS03110
gene id: 880074:BARVI_RS03110
uniprot id: W0EMB1
names: Similarity
messages: Belongs to the glycosyl hydrolase.

880074:BARVI RS00470
gene id: 880074:BARVI_RS00470
uniprot id: W0EQT8
names: Similarity
messages: Belongs to the Fur family.

880074:BARVI RS02470
gene id: 880074:BARVI_RS02470
uniprot id: W0EQT5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

880074:BARVI RS03370
gene id: 880074:BARVI_RS03370
uniprot id: W0ESD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

880074:BARVI RS04235
gene id: 880074:BARVI_RS04235
uniprot id: W0EMY8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

880074:BARVI RS07070
gene id: 880074:BARVI_RS07070
uniprot id: W0ETS2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

880074:BARVI RS04135
gene id: 880074:BARVI_RS04135
uniprot id: W0EMX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

880074:BARVI RS12410
gene id: 880074:BARVI_RS12410
uniprot id: W0EWJ2
names: Similarity
messages: Belongs to the CinA family.

880074:BARVI RS06495
gene id: 880074:BARVI_RS06495
uniprot id: W0ETI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

880074:BARVI RS08040
gene id: 880074:BARVI_RS08040
uniprot id: W0ETA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

880074:BARVI RS06585
gene id: 880074:BARVI_RS06585
uniprot id: W0ETR8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

880074:BARVI RS11515
gene id: 880074:BARVI_RS11515
uniprot id: W0EXY9
names: Similarity
messages: Belongs to the RtcB family.

880074:BARVI RS07460
gene id: 880074:BARVI_RS07460
uniprot id: W0EPJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

880074:BARVI RS02645
gene id: 880074:BARVI_RS02645
uniprot id: W0ERU2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

880074:BARVI RS08085
gene id: 880074:BARVI_RS08085
uniprot id: W0EPT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

880074:BARVI RS05125
gene id: 880074:BARVI_RS05125
uniprot id: W0ET56
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

880074:BARVI RS08825
gene id: 880074:BARVI_RS08825
uniprot id: W0EUJ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS02750
gene id: 880074:BARVI_RS02750
uniprot id: W0ERW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

880074:BARVI RS10900
gene id: 880074:BARVI_RS10900
uniprot id: W0EQZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

880074:BARVI RS02120
gene id: 880074:BARVI_RS02120
uniprot id: W0EM43
names: Similarity
messages: Belongs to the peptidase S41A family.

880074:BARVI RS05080
gene id: 880074:BARVI_RS05080
uniprot id: W0EN80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

880074:BARVI RS03275
gene id: 880074:BARVI_RS03275
uniprot id: W0ER32
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

880074:BARVI RS06065
gene id: 880074:BARVI_RS06065
uniprot id: W0ENU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

880074:BARVI RS01190
gene id: 880074:BARVI_RS01190
uniprot id: W0ELJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

880074:BARVI RS08460
gene id: 880074:BARVI_RS08460
uniprot id: W0EPY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

880074:BARVI RS09265
gene id: 880074:BARVI_RS09265
uniprot id: W0EUR1
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS07360
gene id: 880074:BARVI_RS07360
uniprot id: W0ESX4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

880074:BARVI RS08305
gene id: 880074:BARVI_RS08305
uniprot id: W0EPW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

880074:BARVI RS01010
gene id: 880074:BARVI_RS01010
uniprot id: W0ELG8
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

880074:BARVI RS08785
gene id: 880074:BARVI_RS08785
uniprot id: W0EPX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

880074:BARVI RS06375
gene id: 880074:BARVI_RS06375
uniprot id: W0ENT8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

880074:BARVI RS08485
gene id: 880074:BARVI_RS08485
uniprot id: W0EPT6
names: Similarity
messages: Belongs to the thioredoxin family.

880074:BARVI RS00880
gene id: 880074:BARVI_RS00880
uniprot id: W0ER05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

880074:BARVI RS03915
gene id: 880074:BARVI_RS03915
uniprot id: W0ESK3
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

880074:BARVI RS02745
gene id: 880074:BARVI_RS02745
uniprot id: W0EQW7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

880074:BARVI RS08320
gene id: 880074:BARVI_RS08320
uniprot id: W0EUC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

880074:BARVI RS00035
gene id: 880074:BARVI_RS00035
uniprot id: W0EPL8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

880074:BARVI RS12495
gene id: 880074:BARVI_RS12495
uniprot id: W0EV76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

880074:BARVI RS07010
gene id: 880074:BARVI_RS07010
uniprot id: W0EP98
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

880074:BARVI RS06180
gene id: 880074:BARVI_RS06180
uniprot id: W0ETM3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

880074:BARVI RS08630
gene id: 880074:BARVI_RS08630
uniprot id: W0EQ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

880074:BARVI RS06835
gene id: 880074:BARVI_RS06835
uniprot id: W0ETW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

880074:BARVI RS12910
gene id: 880074:BARVI_RS12910
uniprot id: W0ET51
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

880074:BARVI RS08505
gene id: 880074:BARVI_RS08505
uniprot id: W0ETG7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

880074:BARVI RS08075
gene id: 880074:BARVI_RS08075
uniprot id: W0EPN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

880074:BARVI RS05785
gene id: 880074:BARVI_RS05785
uniprot id: W0ETF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

880074:BARVI RS09675
gene id: 880074:BARVI_RS09675
uniprot id: W0EV86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

880074:BARVI RS07515
gene id: 880074:BARVI_RS07515
uniprot id: W0EPK9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

880074:BARVI RS06020
gene id: 880074:BARVI_RS06020
uniprot id: W0ETC3
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

880074:BARVI RS04945
gene id: 880074:BARVI_RS04945
uniprot id: W0ESV4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

880074:BARVI RS12470
gene id: 880074:BARVI_RS12470
uniprot id: W0EW71
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

880074:BARVI RS02395
gene id: 880074:BARVI_RS02395
uniprot id: W0ERR2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

880074:BARVI RS05240
gene id: 880074:BARVI_RS05240
uniprot id: W0ESZ3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880074:BARVI RS09565
gene id: 880074:BARVI_RS09565
uniprot id: W0EQE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

880074:BARVI RS09810
gene id: 880074:BARVI_RS09810
uniprot id: W0EU01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

880074:BARVI RS04150
gene id: 880074:BARVI_RS04150
uniprot id: W0EMS1
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

880074:BARVI RS00050
gene id: 880074:BARVI_RS00050
uniprot id: W0EQW6
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

880074:BARVI RS10840
gene id: 880074:BARVI_RS10840
uniprot id: W0EVJ7
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS06975
gene id: 880074:BARVI_RS06975
uniprot id: W0EP41
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS06060
gene id: 880074:BARVI_RS06060
uniprot id: W0ETK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

880074:BARVI RS04215
gene id: 880074:BARVI_RS04215
uniprot id: W0EMT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

880074:BARVI RS02675
gene id: 880074:BARVI_RS02675
uniprot id: W0ERU8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

880074:BARVI RS10480
gene id: 880074:BARVI_RS10480
uniprot id: W0EQS5
names: Similarity
messages: Belongs to the AIR synthase family.

880074:BARVI RS03050
gene id: 880074:BARVI_RS03050
uniprot id: W0ER00
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

880074:BARVI RS08925
gene id: 880074:BARVI_RS08925
uniprot id: W0EST8
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS06960
gene id: 880074:BARVI_RS06960
uniprot id: W0EP88
names: Similarity
messages: Belongs to the pyruvate kinase family.

880074:BARVI RS09670
gene id: 880074:BARVI_RS09670
uniprot id: W0EQC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

880074:BARVI RS08235
gene id: 880074:BARVI_RS08235
uniprot id: W0EUB9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

880074:BARVI RS07820
gene id: 880074:BARVI_RS07820
uniprot id: W0ET72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

880074:BARVI RS12735
gene id: 880074:BARVI_RS12735
uniprot id: W0ERR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

880074:BARVI RS04810
gene id: 880074:BARVI_RS04810
uniprot id: W0ET11
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS07260
gene id: 880074:BARVI_RS07260
uniprot id: W0EU48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

880074:BARVI RS00325
gene id: 880074:BARVI_RS00325
uniprot id: W0EL90
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS04115
gene id: 880074:BARVI_RS04115
uniprot id: W0EMR6
names: Subcellular Location Annotation
messages: cytosol

880074:BARVI RS03180
gene id: 880074:BARVI_RS03180
uniprot id: W0EMC1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS09680
gene id: 880074:BARVI_RS09680
uniprot id: W0EQH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

880074:BARVI RS10550
gene id: 880074:BARVI_RS10550
uniprot id: W0EUF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

880074:BARVI RS03070
gene id: 880074:BARVI_RS03070
uniprot id: W0EMH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

880074:BARVI RS11240
gene id: 880074:BARVI_RS11240
uniprot id: W0EW32
names: Similarity
messages: Belongs to the group II decarboxylase family.

880074:BARVI RS08440
gene id: 880074:BARVI_RS08440
uniprot id: W0EPT1
names: Similarity
messages: Belongs to the peptidase C1 family.

880074:BARVI RS10950
gene id: 880074:BARVI_RS10950
uniprot id: W0ER08
names: Similarity
messages: Belongs to the peptidase A31 family.

880074:BARVI RS00185
gene id: 880074:BARVI_RS00185
uniprot id: W0EKY8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

880074:BARVI RS05090
gene id: 880074:BARVI_RS05090
uniprot id: W0ENE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

880074:BARVI RS00645
gene id: 880074:BARVI_RS00645
uniprot id: W0EQW8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

880074:BARVI RS06515
gene id: 880074:BARVI_RS06515
uniprot id: W0ESH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

880074:BARVI RS04570
gene id: 880074:BARVI_RS04570
uniprot id: W0EN69
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

880074:BARVI RS09420
gene id: 880074:BARVI_RS09420
uniprot id: W0EUT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

880074:BARVI RS00095
gene id: 880074:BARVI_RS00095
uniprot id: W0EQW9
names: Similarity
messages: Belongs to the SusD family.

880074:BARVI RS09805
gene id: 880074:BARVI_RS09805
uniprot id: W0EWI3
names: Similarity
messages: Belongs to the peptidase S13 family.

880074:BARVI RS00010
gene id: 880074:BARVI_RS00010
uniprot id: W0EQL4
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

880074:BARVI RS01540
gene id: 880074:BARVI_RS01540
uniprot id: W0ELV4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

880074:BARVI RS02950
gene id: 880074:BARVI_RS02950
uniprot id: W0ERY7
names: Similarity
messages: Belongs to the SusD family.

880074:BARVI RS01615
gene id: 880074:BARVI_RS01615
uniprot id: W0ELW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

880074:BARVI RS05495
gene id: 880074:BARVI_RS05495
uniprot id: W0ES41
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

880074:BARVI RS00675
gene id: 880074:BARVI_RS00675
uniprot id: W0ERZ5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

880074:BARVI RS08025
gene id: 880074:BARVI_RS08025
uniprot id: W0EPM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

880074:BARVI RS10710
gene id: 880074:BARVI_RS10710
uniprot id: W0EUI3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

880074:BARVI RS00310
gene id: 880074:BARVI_RS00310
uniprot id: W0EQR5
names: Similarity
messages: Belongs to the glutamine synthetase family.

880074:BARVI RS07630
gene id: 880074:BARVI_RS07630
uniprot id: W0EUD6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

880074:BARVI RS07830
gene id: 880074:BARVI_RS07830
uniprot id: W0EPK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

880074:BARVI RS00965
gene id: 880074:BARVI_RS00965
uniprot id: W0EQ69
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

880074:BARVI RS05140
gene id: 880074:BARVI_RS05140
uniprot id: W0ESY2
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS06115
gene id: 880074:BARVI_RS06115
uniprot id: W0ETL3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS04065
gene id: 880074:BARVI_RS04065
uniprot id: W0EMW5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

880074:BARVI RS04930
gene id: 880074:BARVI_RS04930
uniprot id: W0ET28
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880074:BARVI RS12445
gene id: 880074:BARVI_RS12445
uniprot id: W0EW67
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS04910
gene id: 880074:BARVI_RS04910
uniprot id: W0ENB5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

880074:BARVI RS02080
gene id: 880074:BARVI_RS02080
uniprot id: W0ERV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

880074:BARVI RS07375
gene id: 880074:BARVI_RS07375
uniprot id: W0EW98
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS03845
gene id: 880074:BARVI_RS03845
uniprot id: W0ESJ4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

880074:BARVI RS12420
gene id: 880074:BARVI_RS12420
uniprot id: W0EV61
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

880074:BARVI RS12575
gene id: 880074:BARVI_RS12575
uniprot id: W0EV92
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

880074:BARVI RS00590
gene id: 880074:BARVI_RS00590
uniprot id: W0ER56
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

880074:BARVI RS01075
gene id: 880074:BARVI_RS01075
uniprot id: W0ELH9
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

880074:BARVI RS00640
gene id: 880074:BARVI_RS00640
uniprot id: W0EPX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS00775
gene id: 880074:BARVI_RS00775
uniprot id: W0ER90
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

880074:BARVI RS04355
gene id: 880074:BARVI_RS04355
uniprot id: W0ESV3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880074:BARVI RS12515
gene id: 880074:BARVI_RS12515
uniprot id: W0ERR9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

880074:BARVI RS09225
gene id: 880074:BARVI_RS09225
uniprot id: W0EQ48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

880074:BARVI RS12395
gene id: 880074:BARVI_RS12395
uniprot id: W0EW57
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS02665
gene id: 880074:BARVI_RS02665
uniprot id: W0EMA9
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS08870
gene id: 880074:BARVI_RS08870
uniprot id: W0EQ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

880074:BARVI RS10995
gene id: 880074:BARVI_RS10995
uniprot id: W0EUM7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

880074:BARVI RS03030
gene id: 880074:BARVI_RS03030
uniprot id: W0EM97
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

880074:BARVI RS04405
gene id: 880074:BARVI_RS04405
uniprot id: W0ERN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

880074:BARVI RS09715
gene id: 880074:BARVI_RS09715
uniprot id: W0EUY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880074:BARVI RS11145
gene id: 880074:BARVI_RS11145
uniprot id: W0ER72
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

880074:BARVI RS10835
gene id: 880074:BARVI_RS10835
uniprot id: W0EUK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

880074:BARVI RS09060
gene id: 880074:BARVI_RS09060
uniprot id: W0EQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

880074:BARVI RS08920
gene id: 880074:BARVI_RS08920
uniprot id: W0EPZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

880074:BARVI RS05925
gene id: 880074:BARVI_RS05925
uniprot id: W0ENR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

880074:BARVI RS09650
gene id: 880074:BARVI_RS09650
uniprot id: W0EV82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

880074:BARVI RS05440
gene id: 880074:BARVI_RS05440
uniprot id: W0ENJ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880074:BARVI RS07395
gene id: 880074:BARVI_RS07395
uniprot id: W0EPH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

880074:BARVI RS07425
gene id: 880074:BARVI_RS07425
uniprot id: W0EUA7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

880074:BARVI RS09925
gene id: 880074:BARVI_RS09925
uniprot id: W0EQL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

880074:BARVI RS06905
gene id: 880074:BARVI_RS06905
uniprot id: W0ETP3
names: Similarity
messages: Belongs to the DEAD box helicase family.

880074:BARVI RS02990
gene id: 880074:BARVI_RS02990
uniprot id: W0EM90
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

880074:BARVI RS05035
gene id: 880074:BARVI_RS05035
uniprot id: W0ESW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

880074:BARVI RS05030
gene id: 880074:BARVI_RS05030
uniprot id: W0ERX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

880074:BARVI RS10495
gene id: 880074:BARVI_RS10495
uniprot id: W0EUD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

880074:BARVI RS07790
gene id: 880074:BARVI_RS07790
uniprot id: W0EU63
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

880074:BARVI RS11275
gene id: 880074:BARVI_RS11275
uniprot id: W0ER91
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

880074:BARVI RS07715
gene id: 880074:BARVI_RS07715
uniprot id: W0ET59
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

880074:BARVI RS07115
gene id: 880074:BARVI_RS07115
uniprot id: W0ESS9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

880074:BARVI RS09160
gene id: 880074:BARVI_RS09160
uniprot id: W0ETQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

880074:BARVI RS01520
gene id: 880074:BARVI_RS01520
uniprot id: W0EQF0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS00595
gene id: 880074:BARVI_RS00595
uniprot id: W0ELD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

880074:BARVI RS03380
gene id: 880074:BARVI_RS03380
uniprot id: W0ER45
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

880074:BARVI RS04160
gene id: 880074:BARVI_RS04160
uniprot id: W0EMX8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

880074:BARVI RS04705
gene id: 880074:BARVI_RS04705
uniprot id: W0ERS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

880074:BARVI RS00245
gene id: 880074:BARVI_RS00245
uniprot id: W0EQZ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

880074:BARVI RS04350
gene id: 880074:BARVI_RS04350
uniprot id: W0EMY3
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS01085
gene id: 880074:BARVI_RS01085
uniprot id: W0ELN8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

880074:BARVI RS11200
gene id: 880074:BARVI_RS11200
uniprot id: W0EVP8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880074:BARVI RS03390
gene id: 880074:BARVI_RS03390
uniprot id: W0ES60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

880074:BARVI RS00380
gene id: 880074:BARVI_RS00380
uniprot id: W0ER21
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS06105
gene id: 880074:BARVI_RS06105
uniprot id: W0ETD8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880074:BARVI RS02150
gene id: 880074:BARVI_RS02150
uniprot id: W0EM47
names: Similarity
messages: Belongs to the peptidase M16 family.

880074:BARVI RS01850
gene id: 880074:BARVI_RS01850
uniprot id: W0ELT6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

880074:BARVI RS08935
gene id: 880074:BARVI_RS08935
uniprot id: W0EQ42
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

880074:BARVI RS08145
gene id: 880074:BARVI_RS08145
uniprot id: W0EUA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

880074:BARVI RS09185
gene id: 880074:BARVI_RS09185
uniprot id: W0EQ85
names: Similarity
messages: Belongs to the UPF0102 family.

880074:BARVI RS04645
gene id: 880074:BARVI_RS04645
uniprot id: W0EN77
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

880074:BARVI RS08875
gene id: 880074:BARVI_RS08875
uniprot id: W0ETL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

880074:BARVI RS08160
gene id: 880074:BARVI_RS08160
uniprot id: W0EPU9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

880074:BARVI RS05445
gene id: 880074:BARVI_RS05445
uniprot id: W0ES32
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS05725
gene id: 880074:BARVI_RS05725
uniprot id: W0ENN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

880074:BARVI RS01640
gene id: 880074:BARVI_RS01640
uniprot id: W0ELX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

880074:BARVI RS00735
gene id: 880074:BARVI_RS00735
uniprot id: W0ER84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

880074:BARVI RS09530
gene id: 880074:BARVI_RS09530
uniprot id: W0EV63
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

880074:BARVI RS09520
gene id: 880074:BARVI_RS09520
uniprot id: W0EUV0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

880074:BARVI RS04900
gene id: 880074:BARVI_RS04900
uniprot id: W0EN54
names: Similarity
messages: Belongs to the MreC family.

880074:BARVI RS10975
gene id: 880074:BARVI_RS10975
uniprot id: W0ER13
names: Similarity
messages: Belongs to the HypD family.

880074:BARVI RS07805
gene id: 880074:BARVI_RS07805
uniprot id: W0EUF7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

880074:BARVI RS04525
gene id: 880074:BARVI_RS04525
uniprot id: W0ESX5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880074:BARVI RS06775
gene id: 880074:BARVI_RS06775
uniprot id: W0EP08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

880074:BARVI RS07385
gene id: 880074:BARVI_RS07385
uniprot id: W0EPC1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880074:BARVI RS07255
gene id: 880074:BARVI_RS07255
uniprot id: W0EP99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

880074:BARVI RS06400
gene id: 880074:BARVI_RS06400
uniprot id: W0ENZ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS07390
gene id: 880074:BARVI_RS07390
uniprot id: W0EU88
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS12440
gene id: 880074:BARVI_RS12440
uniprot id: W0EV66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

880074:BARVI RS00020
gene id: 880074:BARVI_RS00020
uniprot id: W0EKW2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

880074:BARVI RS04665
gene id: 880074:BARVI_RS04665
uniprot id: W0ESZ2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

880074:BARVI RS05245
gene id: 880074:BARVI_RS05245
uniprot id: W0ENA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

880074:BARVI RS02375
gene id: 880074:BARVI_RS02375
uniprot id: W0EM15
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

880074:BARVI RS08250
gene id: 880074:BARVI_RS08250
uniprot id: W0EPQ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

880074:BARVI RS12580
gene id: 880074:BARVI_RS12580
uniprot id: W0EW91
names: Similarity
messages: Belongs to the UPF0246 family.

880074:BARVI RS05395
gene id: 880074:BARVI_RS05395
uniprot id: W0ETA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS06535
gene id: 880074:BARVI_RS06535
uniprot id: W0ENW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

880074:BARVI RS03965
gene id: 880074:BARVI_RS03965
uniprot id: W0EMU9
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS08915
gene id: 880074:BARVI_RS08915
uniprot id: W0EUK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

880074:BARVI RS07620
gene id: 880074:BARVI_RS07620
uniprot id: W0EU43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

880074:BARVI RS02405
gene id: 880074:BARVI_RS02405
uniprot id: W0ES07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

880074:BARVI RS10675
gene id: 880074:BARVI_RS10675
uniprot id: W0ER11
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

880074:BARVI RS03375
gene id: 880074:BARVI_RS03375
uniprot id: W0EMM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

880074:BARVI RS07345
gene id: 880074:BARVI_RS07345
uniprot id: W0EU69
names: Similarity
messages: Belongs to the GARS family.

880074:BARVI RS09575
gene id: 880074:BARVI_RS09575
uniprot id: W0EUW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

880074:BARVI RS00355
gene id: 880074:BARVI_RS00355
uniprot id: W0EL96
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

880074:BARVI RS06110
gene id: 880074:BARVI_RS06110
uniprot id: W0ENP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

880074:BARVI RS01285
gene id: 880074:BARVI_RS01285
uniprot id: W0ERJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

880074:BARVI RS11210
gene id: 880074:BARVI_RS11210
uniprot id: W0EW27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

880074:BARVI RS10360
gene id: 880074:BARVI_RS10360
uniprot id: W0EU99
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

880074:BARVI RS06440
gene id: 880074:BARVI_RS06440
uniprot id: W0ETI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

880074:BARVI RS11245
gene id: 880074:BARVI_RS11245
uniprot id: W0ER86
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

880074:BARVI RS12640
gene id: 880074:BARVI_RS12640
uniprot id: W0EVA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

880074:BARVI RS10980
gene id: 880074:BARVI_RS10980
uniprot id: W0EVZ5
names: Similarity
messages: Belongs to the HupF/HypC family.

880074:BARVI RS00545
gene id: 880074:BARVI_RS00545
uniprot id: W0EPW3
names: Similarity
messages: Belongs to the peptidase S1C family.

880074:BARVI RS10720
gene id: 880074:BARVI_RS10720
uniprot id: W0EVH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

880074:BARVI RS10930
gene id: 880074:BARVI_RS10930
uniprot id: W0EVY6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880074:BARVI RS01455
gene id: 880074:BARVI_RS01455
uniprot id: W0ELU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880074:BARVI RS04005
gene id: 880074:BARVI_RS04005
uniprot id: W0ERD0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

880074:BARVI RS02295
gene id: 880074:BARVI_RS02295
uniprot id: W0EM69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

880074:BARVI RS10925
gene id: 880074:BARVI_RS10925
uniprot id: W0ER04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

880074:BARVI RS04210
gene id: 880074:BARVI_RS04210
uniprot id: W0ESH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

880074:BARVI RS01860
gene id: 880074:BARVI_RS01860
uniprot id: W0EM07
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

880074:BARVI RS11235
gene id: 880074:BARVI_RS11235
uniprot id: W0ER43
names: Subcellular Location Annotation
messages: Membrane

880074:BARVI RS00440
gene id: 880074:BARVI_RS00440
uniprot id: W0EL41
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

880074:BARVI RS00045
gene id: 880074:BARVI_RS00045
uniprot id: W0EKW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.