880072:DESAC RS13420
gene id: 880072:DESAC_RS13420
uniprot id: F2NIN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

880072:DESAC RS06775
gene id: 880072:DESAC_RS06775
uniprot id: F2NHM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

880072:DESAC RS02415
gene id: 880072:DESAC_RS02415
uniprot id: F2NF31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

880072:DESAC RS06845
gene id: 880072:DESAC_RS06845
uniprot id: F2NHP2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

880072:DESAC RS01255
gene id: 880072:DESAC_RS01255
uniprot id: F2NEF8
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

880072:DESAC RS08935
gene id: 880072:DESAC_RS08935
uniprot id: F2NI04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

880072:DESAC RS01970
gene id: 880072:DESAC_RS01970
uniprot id: F2NEU7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

880072:DESAC RS11150
gene id: 880072:DESAC_RS11150
uniprot id: F2NFE9
names: Similarity
messages: Belongs to the CobH/CbiC family.

880072:DESAC RS06170
gene id: 880072:DESAC_RS06170
uniprot id: F2NCG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

880072:DESAC RS05135
gene id: 880072:DESAC_RS05135
uniprot id: F2NH61
names: Similarity
messages: Belongs to the glutamate synthase family.

880072:DESAC RS07275
gene id: 880072:DESAC_RS07275
uniprot id: F2NJE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

880072:DESAC RS04705
gene id: 880072:DESAC_RS04705
uniprot id: F2NC24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

880072:DESAC RS13500
gene id: 880072:DESAC_RS13500
uniprot id: F2NIQ2
names: Similarity
messages: Belongs to the universal stress protein A family.

880072:DESAC RS04240
gene id: 880072:DESAC_RS04240
uniprot id: F2NGV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

880072:DESAC RS08695
gene id: 880072:DESAC_RS08695
uniprot id: F2ND12
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

880072:DESAC RS07180
gene id: 880072:DESAC_RS07180
uniprot id: F2NJC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

880072:DESAC RS09125
gene id: 880072:DESAC_RS09125
uniprot id: F2NI42
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880072:DESAC RS04875
gene id: 880072:DESAC_RS04875
uniprot id: F2NC57
names: Similarity
messages: Belongs to the FeoA family.

880072:DESAC RS04775
gene id: 880072:DESAC_RS04775
uniprot id: F2NC36
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

880072:DESAC RS03585
gene id: 880072:DESAC_RS03585
uniprot id: F2NGJ0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

880072:DESAC RS12940
gene id: 880072:DESAC_RS12940
uniprot id: F2NDR9
names: Similarity
messages: Belongs to the UPF0047 family.

880072:DESAC RS00185
gene id: 880072:DESAC_RS00185
uniprot id: F2NGM9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

880072:DESAC RS12855
gene id: 880072:DESAC_RS12855
uniprot id: F2NDQ2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

880072:DESAC RS00725
gene id: 880072:DESAC_RS00725
uniprot id: F2NBW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS14280
gene id: 880072:DESAC_RS14280
uniprot id: F2NIW8
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS04865
gene id: 880072:DESAC_RS04865
uniprot id: F2NC55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

880072:DESAC RS00080
gene id: 880072:DESAC_RS00080
uniprot id: F2NGK8
names: Similarity
messages: Belongs to the fabD family.

880072:DESAC RS07075
gene id: 880072:DESAC_RS07075
uniprot id: F2NJA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

880072:DESAC RS07120
gene id: 880072:DESAC_RS07120
uniprot id: F2NJB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

880072:DESAC RS05500
gene id: 880072:DESAC_RS05500
uniprot id: F2NCA7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

880072:DESAC RS10475
gene id: 880072:DESAC_RS10475
uniprot id: F2NJZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

880072:DESAC RS01855
gene id: 880072:DESAC_RS01855
uniprot id: F2NES9
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

880072:DESAC RS11745
gene id: 880072:DESAC_RS11745
uniprot id: F2NFR2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS09465
gene id: 880072:DESAC_RS09465
uniprot id: F2NJT0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

880072:DESAC RS13145
gene id: 880072:DESAC_RS13145
uniprot id: F2NDW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

880072:DESAC RS10025
gene id: 880072:DESAC_RS10025
uniprot id: F2NI74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

880072:DESAC RS13400
gene id: 880072:DESAC_RS13400
uniprot id: F2NIN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

880072:DESAC RS07500
gene id: 880072:DESAC_RS07500
uniprot id: F2NCS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS03160
gene id: 880072:DESAC_RS03160
uniprot id: F2NGA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

880072:DESAC RS07175
gene id: 880072:DESAC_RS07175
uniprot id: F2NJC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

880072:DESAC RS04945
gene id: 880072:DESAC_RS04945
uniprot id: F2NC71
names: Similarity
messages: Belongs to the GreA/GreB family.

880072:DESAC RS09395
gene id: 880072:DESAC_RS09395
uniprot id: F2NJR6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

880072:DESAC RS04655
gene id: 880072:DESAC_RS04655
uniprot id: F2NH37
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

880072:DESAC RS07685
gene id: 880072:DESAC_RS07685
uniprot id: F2NHR2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

880072:DESAC RS12220
gene id: 880072:DESAC_RS12220
uniprot id: F2NDJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

880072:DESAC RS03720
gene id: 880072:DESAC_RS03720
uniprot id: F2NF75
names: Subcellular Location Annotation
messages: Cytoplasm

880072:DESAC RS12230
gene id: 880072:DESAC_RS12230
uniprot id: F2NDK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

880072:DESAC RS05115
gene id: 880072:DESAC_RS05115
uniprot id: F2NH57
names: Similarity
messages: Belongs to the peptidase M16 family.

880072:DESAC RS13740
gene id: 880072:DESAC_RS13740
uniprot id: F2NE06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

880072:DESAC RS05280
gene id: 880072:DESAC_RS05280
uniprot id: F2NH88
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Belongs to the complex I 51 kDa subunit family.

880072:DESAC RS05815
gene id: 880072:DESAC_RS05815
uniprot id: F2NHB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

880072:DESAC RS13980
gene id: 880072:DESAC_RS13980
uniprot id: F2NIR4
names: Similarity
messages: Belongs to the RecJ family.

880072:DESAC RS12825
gene id: 880072:DESAC_RS12825
uniprot id: F2NIJ1
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

880072:DESAC RS12845
gene id: 880072:DESAC_RS12845
uniprot id: F2NDQ0
names: Similarity
messages: Belongs to the HepT RNase toxin family.

880072:DESAC RS13760
gene id: 880072:DESAC_RS13760
uniprot id: F2NE10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS12770
gene id: 880072:DESAC_RS12770
uniprot id: F2NII0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

880072:DESAC RS10860
gene id: 880072:DESAC_RS10860
uniprot id: F2NDE6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

880072:DESAC RS07570
gene id: 880072:DESAC_RS07570
uniprot id: F2NCU3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

880072:DESAC RS08840
gene id: 880072:DESAC_RS08840
uniprot id: F2NHY7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

880072:DESAC RS15265
gene id: 880072:DESAC_RS15265
uniprot id: F2ND16
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS03605
gene id: 880072:DESAC_RS03605
uniprot id: F2NF52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

880072:DESAC RS13985
gene id: 880072:DESAC_RS13985
uniprot id: F2NIR5
names: Similarity
messages: Belongs to the UPF0173 family.

880072:DESAC RS10770
gene id: 880072:DESAC_RS10770
uniprot id: F2NDC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
messages: Homodimer.

880072:DESAC RS01815
gene id: 880072:DESAC_RS01815
uniprot id: F2NES2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

880072:DESAC RS01470
gene id: 880072:DESAC_RS01470
uniprot id: F2NEK0
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

880072:DESAC RS06690
gene id: 880072:DESAC_RS06690
uniprot id: F2NHL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

880072:DESAC RS10015
gene id: 880072:DESAC_RS10015
uniprot id: F2NI72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

880072:DESAC RS14320
gene id: 880072:DESAC_RS14320
uniprot id: F2NE39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

880072:DESAC RS11735
gene id: 880072:DESAC_RS11735
uniprot id: F2NFR0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

880072:DESAC RS01710
gene id: 880072:DESAC_RS01710
uniprot id: F2NEQ1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

880072:DESAC RS02855
gene id: 880072:DESAC_RS02855
uniprot id: F2NG50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

880072:DESAC RS03490
gene id: 880072:DESAC_RS03490
uniprot id: F2NGH1
names: Similarity
messages: Belongs to the YkuD family.

880072:DESAC RS03355
gene id: 880072:DESAC_RS03355
uniprot id: F2NGE7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS04230
gene id: 880072:DESAC_RS04230
uniprot id: F2NGV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

880072:DESAC RS02170
gene id: 880072:DESAC_RS02170
uniprot id: F2NEY3
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

880072:DESAC RS01555
gene id: 880072:DESAC_RS01555
uniprot id: F2NEL9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

880072:DESAC RS03410
gene id: 880072:DESAC_RS03410
uniprot id: F2NGF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

880072:DESAC RS01840
gene id: 880072:DESAC_RS01840
uniprot id: F2NES6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

880072:DESAC RS03955
gene id: 880072:DESAC_RS03955
uniprot id: F2NGQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS03695
gene id: 880072:DESAC_RS03695
uniprot id: F2NF70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

880072:DESAC RS08035
gene id: 880072:DESAC_RS08035
uniprot id: F2NJF5
names: Similarity
messages: Belongs to the MEMO1 family.

880072:DESAC RS02720
gene id: 880072:DESAC_RS02720
uniprot id: F2NG22
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

880072:DESAC RS00655
gene id: 880072:DESAC_RS00655
uniprot id: F2NJ69
names: Similarity
messages: Belongs to the peptidase M18 family.

880072:DESAC RS13510
gene id: 880072:DESAC_RS13510
uniprot id: F2NIQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

880072:DESAC RS04920
gene id: 880072:DESAC_RS04920
uniprot id: F2NC66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

880072:DESAC RS05680
gene id: 880072:DESAC_RS05680
uniprot id: F2NCE3
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

880072:DESAC RS01700
gene id: 880072:DESAC_RS01700
uniprot id: F2NEP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

880072:DESAC RS07655
gene id: 880072:DESAC_RS07655
uniprot id: F2NHQ6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

880072:DESAC RS09145
gene id: 880072:DESAC_RS09145
uniprot id: F2NI46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

880072:DESAC RS06630
gene id: 880072:DESAC_RS06630
uniprot id: F2NHK2
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS05300
gene id: 880072:DESAC_RS05300
uniprot id: F2NH92
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Belongs to the complex I 51 kDa subunit family.

880072:DESAC RS02850
gene id: 880072:DESAC_RS02850
uniprot id: F2NG49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

880072:DESAC RS13820
gene id: 880072:DESAC_RS13820
uniprot id: F2NE21
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

880072:DESAC RS05645
gene id: 880072:DESAC_RS05645
uniprot id: F2NCD6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

880072:DESAC RS13180
gene id: 880072:DESAC_RS13180
uniprot id: F2NDW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

880072:DESAC RS02000
gene id: 880072:DESAC_RS02000
uniprot id: F2NEV3
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

880072:DESAC RS12915
gene id: 880072:DESAC_RS12915
uniprot id: F2NDR4
names: Similarity
messages: Belongs to the Ahb/Nir family.

880072:DESAC RS05330
gene id: 880072:DESAC_RS05330
uniprot id: F2NH98
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

880072:DESAC RS12415
gene id: 880072:DESAC_RS12415
uniprot id: F2NDN8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS01720
gene id: 880072:DESAC_RS01720
uniprot id: F2NEQ3
names: Similarity
messages: Belongs to the P(II) protein family.

880072:DESAC RS12225
gene id: 880072:DESAC_RS12225
uniprot id: F2NDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

880072:DESAC RS12960
gene id: 880072:DESAC_RS12960
uniprot id: F2NDS4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

880072:DESAC RS02325
gene id: 880072:DESAC_RS02325
uniprot id: F2NF13
names: Similarity
messages: Belongs to the peptidase S41A family.

880072:DESAC RS00685
gene id: 880072:DESAC_RS00685
uniprot id: F2NBV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

880072:DESAC RS00120
gene id: 880072:DESAC_RS00120
uniprot id: F2NGL6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

880072:DESAC RS06205
gene id: 880072:DESAC_RS06205
uniprot id: F2NCH4
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS01165
gene id: 880072:DESAC_RS01165
uniprot id: F2NEE0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

880072:DESAC RS07560
gene id: 880072:DESAC_RS07560
uniprot id: F2NCU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

880072:DESAC RS14480
gene id: 880072:DESAC_RS14480
uniprot id: F2NE69
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS00840
gene id: 880072:DESAC_RS00840
uniprot id: F2NBY9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

880072:DESAC RS11395
gene id: 880072:DESAC_RS11395
uniprot id: F2NFJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

880072:DESAC RS12395
gene id: 880072:DESAC_RS12395
uniprot id: F2NDN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

880072:DESAC RS01345
gene id: 880072:DESAC_RS01345
uniprot id: F2NEH5
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

880072:DESAC RS03735
gene id: 880072:DESAC_RS03735
uniprot id: F2NF78
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880072:DESAC RS03015
gene id: 880072:DESAC_RS03015
uniprot id: F2NG81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

880072:DESAC RS01500
gene id: 880072:DESAC_RS01500
uniprot id: F2NEK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

880072:DESAC RS10705
gene id: 880072:DESAC_RS10705
uniprot id: F2NDB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

880072:DESAC RS04940
gene id: 880072:DESAC_RS04940
uniprot id: F2NC70
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS09485
gene id: 880072:DESAC_RS09485
uniprot id: F2NJT4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS03515
gene id: 880072:DESAC_RS03515
uniprot id: F2NGH6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS11880
gene id: 880072:DESAC_RS11880
uniprot id: F2NFT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

880072:DESAC RS05955
gene id: 880072:DESAC_RS05955
uniprot id: F2NHE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

880072:DESAC RS11930
gene id: 880072:DESAC_RS11930
uniprot id: F2NFU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

880072:DESAC RS15095
gene id: 880072:DESAC_RS15095
uniprot id: F2NHA6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

880072:DESAC RS03590
gene id: 880072:DESAC_RS03590
uniprot id: F2NGJ1
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

880072:DESAC RS10465
gene id: 880072:DESAC_RS10465
uniprot id: F2NJY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880072:DESAC RS12210
gene id: 880072:DESAC_RS12210
uniprot id: F2NDJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

880072:DESAC RS14555
gene id: 880072:DESAC_RS14555
uniprot id: F2NE84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

880072:DESAC RS01705
gene id: 880072:DESAC_RS01705
uniprot id: F2NEQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

880072:DESAC RS02755
gene id: 880072:DESAC_RS02755
uniprot id: F2NG29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

880072:DESAC RS01620
gene id: 880072:DESAC_RS01620
uniprot id: F2NEN2
names: Similarity
messages: Belongs to the threonine synthase family.

880072:DESAC RS07775
gene id: 880072:DESAC_RS07775
uniprot id: F2NHT1
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS01760
gene id: 880072:DESAC_RS01760
uniprot id: F2NER1
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS07285
gene id: 880072:DESAC_RS07285
uniprot id: F2NJE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

880072:DESAC RS13745
gene id: 880072:DESAC_RS13745
uniprot id: F2NE07
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

880072:DESAC RS14535
gene id: 880072:DESAC_RS14535
uniprot id: F2NE80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

880072:DESAC RS10280
gene id: 880072:DESAC_RS10280
uniprot id: F2NJV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

880072:DESAC RS02075
gene id: 880072:DESAC_RS02075
uniprot id: F2NEW6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

880072:DESAC RS11535
gene id: 880072:DESAC_RS11535
uniprot id: F2NFM1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS03680
gene id: 880072:DESAC_RS03680
uniprot id: F2NF67
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

880072:DESAC RS06060
gene id: 880072:DESAC_RS06060
uniprot id: F2NHG5
names: Similarity
messages: Belongs to the universal stress protein A family.

880072:DESAC RS09320
gene id: 880072:DESAC_RS09320
uniprot id: F2NJQ2
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

880072:DESAC RS05305
gene id: 880072:DESAC_RS05305
uniprot id: F2NH93
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

880072:DESAC RS02150
gene id: 880072:DESAC_RS02150
uniprot id: F2NEX9
names: Similarity
messages: Belongs to the universal stress protein A family.

880072:DESAC RS08670
gene id: 880072:DESAC_RS08670
uniprot id: F2ND07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

880072:DESAC RS15060
gene id: 880072:DESAC_RS15060
uniprot id: F2NC47
names: Similarity
messages: Belongs to the FeoA family.

880072:DESAC RS01745
gene id: 880072:DESAC_RS01745
uniprot id: F2NEQ8
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

880072:DESAC RS11975
gene id: 880072:DESAC_RS11975
uniprot id: F2NFV7
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

880072:DESAC RS01640
gene id: 880072:DESAC_RS01640
uniprot id: F2NEN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

880072:DESAC RS14515
gene id: 880072:DESAC_RS14515
uniprot id: F2NE76
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

880072:DESAC RS11380
gene id: 880072:DESAC_RS11380
uniprot id: F2NFJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

880072:DESAC RS13695
gene id: 880072:DESAC_RS13695
uniprot id: F2NDZ7
names: Similarity
messages: Belongs to the universal stress protein A family.

880072:DESAC RS05760
gene id: 880072:DESAC_RS05760
uniprot id: F2NCF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

880072:DESAC RS09425
gene id: 880072:DESAC_RS09425
uniprot id: F2NJS2
names: Similarity
messages: Belongs to the NodU/CmcH family.

880072:DESAC RS01370
gene id: 880072:DESAC_RS01370
uniprot id: F2NEH9
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS07000
gene id: 880072:DESAC_RS07000
uniprot id: F2NJ90
names: Similarity
messages: Belongs to the UbiD family.

880072:DESAC RS01325
gene id: 880072:DESAC_RS01325
uniprot id: F2NEH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

880072:DESAC RS14485
gene id: 880072:DESAC_RS14485
uniprot id: F2NE70
names: Similarity
messages: Belongs to the peptidase S11 family.

880072:DESAC RS06530
gene id: 880072:DESAC_RS06530
uniprot id: F2NCN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

880072:DESAC RS01670
gene id: 880072:DESAC_RS01670
uniprot id: F2NEP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

880072:DESAC RS07780
gene id: 880072:DESAC_RS07780
uniprot id: F2NHT2
names: Similarity
messages: Belongs to the DNA photolyase class-2 family.

880072:DESAC RS15270
gene id: 880072:DESAC_RS15270
uniprot id: F2NHZ1
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS05590
gene id: 880072:DESAC_RS05590
uniprot id: F2NCC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

880072:DESAC RS05845
gene id: 880072:DESAC_RS05845
uniprot id: F2NHC4
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

880072:DESAC RS09510
gene id: 880072:DESAC_RS09510
uniprot id: F2NJT9
names: Caution
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

880072:DESAC RS14055
gene id: 880072:DESAC_RS14055
uniprot id: F2NIS9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880072:DESAC RS11690
gene id: 880072:DESAC_RS11690
uniprot id: F2NFQ1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

880072:DESAC RS00695
gene id: 880072:DESAC_RS00695
uniprot id: F2NBV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

880072:DESAC RS02145
gene id: 880072:DESAC_RS02145
uniprot id: F2NEX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

880072:DESAC RS05735
gene id: 880072:DESAC_RS05735
uniprot id: F2NCF3
names: Similarity
messages: Belongs to the KptA/TPT1 family.

880072:DESAC RS04275
gene id: 880072:DESAC_RS04275
uniprot id: F2NGW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS15450
gene id: 880072:DESAC_RS15450
uniprot id: F2NDT8
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS02395
gene id: 880072:DESAC_RS02395
uniprot id: F2NF27
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

880072:DESAC RS06430
gene id: 880072:DESAC_RS06430
uniprot id: F2NCL6
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

880072:DESAC RS00265
gene id: 880072:DESAC_RS00265
uniprot id: F2NGP5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

880072:DESAC RS12005
gene id: 880072:DESAC_RS12005
uniprot id: F2NFW4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

880072:DESAC RS10110
gene id: 880072:DESAC_RS10110
uniprot id: F2NI91
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

880072:DESAC RS07880
gene id: 880072:DESAC_RS07880
uniprot id: F2NHV3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

880072:DESAC RS04280
gene id: 880072:DESAC_RS04280
uniprot id: F2NGW8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

880072:DESAC RS10565
gene id: 880072:DESAC_RS10565
uniprot id: F2NK10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

880072:DESAC RS04220
gene id: 880072:DESAC_RS04220
uniprot id: F2NGV5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS02385
gene id: 880072:DESAC_RS02385
uniprot id: F2NF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS04185
gene id: 880072:DESAC_RS04185
uniprot id: F2NGU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

880072:DESAC RS02860
gene id: 880072:DESAC_RS02860
uniprot id: F2NG51
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

880072:DESAC RS12870
gene id: 880072:DESAC_RS12870
uniprot id: F2NDQ5
names: Similarity
messages: Belongs to the peptidase S49 family.

880072:DESAC RS10470
gene id: 880072:DESAC_RS10470
uniprot id: F2NJZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

880072:DESAC RS02725
gene id: 880072:DESAC_RS02725
uniprot id: F2NG23
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

880072:DESAC RS07375
gene id: 880072:DESAC_RS07375
uniprot id: F2NCQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

880072:DESAC RS07495
gene id: 880072:DESAC_RS07495
uniprot id: F2NCS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

880072:DESAC RS05130
gene id: 880072:DESAC_RS05130
uniprot id: F2NH60
names: Similarity
messages: Belongs to the glutamate synthase family.

880072:DESAC RS01695
gene id: 880072:DESAC_RS01695
uniprot id: F2NEP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

880072:DESAC RS06900
gene id: 880072:DESAC_RS06900
uniprot id: F2NHQ3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880072:DESAC RS00030
gene id: 880072:DESAC_RS00030
uniprot id: F2NGJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS10640
gene id: 880072:DESAC_RS10640
uniprot id: F2NDA3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

880072:DESAC RS13815
gene id: 880072:DESAC_RS13815
uniprot id: F2NE20
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

880072:DESAC RS10270
gene id: 880072:DESAC_RS10270
uniprot id: F2NJU8
names: Similarity
messages: Belongs to the histone deacetylase family.

880072:DESAC RS06825
gene id: 880072:DESAC_RS06825
uniprot id: F2NHN8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

880072:DESAC RS05520
gene id: 880072:DESAC_RS05520
uniprot id: F2NCB1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

880072:DESAC RS09570
gene id: 880072:DESAC_RS09570
uniprot id: F2ND31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

880072:DESAC RS12840
gene id: 880072:DESAC_RS12840
uniprot id: F2NDP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880072:DESAC RS02260
gene id: 880072:DESAC_RS02260
uniprot id: F2NF00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

880072:DESAC RS05620
gene id: 880072:DESAC_RS05620
uniprot id: F2NCD1
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS02580
gene id: 880072:DESAC_RS02580
uniprot id: F2NFZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS07025
gene id: 880072:DESAC_RS07025
uniprot id: F2NJ95
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

880072:DESAC RS02980
gene id: 880072:DESAC_RS02980
uniprot id: F2NG74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

880072:DESAC RS07295
gene id: 880072:DESAC_RS07295
uniprot id: F2NCN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

880072:DESAC RS05820
gene id: 880072:DESAC_RS05820
uniprot id: F2NHB9
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

880072:DESAC RS12760
gene id: 880072:DESAC_RS12760
uniprot id: F2NIH8
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

880072:DESAC RS14315
gene id: 880072:DESAC_RS14315
uniprot id: F2NIX4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

880072:DESAC RS12830
gene id: 880072:DESAC_RS12830
uniprot id: F2NDP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

880072:DESAC RS03285
gene id: 880072:DESAC_RS03285
uniprot id: F2NGD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

880072:DESAC RS14645
gene id: 880072:DESAC_RS14645
uniprot id: F2NEA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

880072:DESAC RS06505
gene id: 880072:DESAC_RS06505
uniprot id: F2NCN0
names: Subcellular Location Annotation
messages: Cytoplasm

880072:DESAC RS06390
gene id: 880072:DESAC_RS06390
uniprot id: F2NCK8
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS01575
gene id: 880072:DESAC_RS01575
uniprot id: F2NEM3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

880072:DESAC RS04805
gene id: 880072:DESAC_RS04805
uniprot id: F2NC41
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

880072:DESAC RS06200
gene id: 880072:DESAC_RS06200
uniprot id: F2NCH3
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS09740
gene id: 880072:DESAC_RS09740
uniprot id: F2ND60
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

880072:DESAC RS10060
gene id: 880072:DESAC_RS10060
uniprot id: F2NI81
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS07865
gene id: 880072:DESAC_RS07865
uniprot id: F2NHV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

880072:DESAC RS07250
gene id: 880072:DESAC_RS07250
uniprot id: F2NJD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

880072:DESAC RS14120
gene id: 880072:DESAC_RS14120
uniprot id: F2NIU2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS04890
gene id: 880072:DESAC_RS04890
uniprot id: F2NC60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

880072:DESAC RS11875
gene id: 880072:DESAC_RS11875
uniprot id: F2NFT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880072:DESAC RS08795
gene id: 880072:DESAC_RS08795
uniprot id: F2NHX8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

880072:DESAC RS08025
gene id: 880072:DESAC_RS08025
uniprot id: F2NJF3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

880072:DESAC RS06355
gene id: 880072:DESAC_RS06355
uniprot id: F2NCK1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

880072:DESAC RS14565
gene id: 880072:DESAC_RS14565
uniprot id: F2NE86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

880072:DESAC RS11255
gene id: 880072:DESAC_RS11255
uniprot id: F2NFG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

880072:DESAC RS02975
gene id: 880072:DESAC_RS02975
uniprot id: F2NG73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS12080
gene id: 880072:DESAC_RS12080
uniprot id: F2NDH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS08215
gene id: 880072:DESAC_RS08215
uniprot id: F2NJI7
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

880072:DESAC RS04545
gene id: 880072:DESAC_RS04545
uniprot id: F2NH15
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

880072:DESAC RS06915
gene id: 880072:DESAC_RS06915
uniprot id: F2NJ71
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

880072:DESAC RS03775
gene id: 880072:DESAC_RS03775
uniprot id: F2NF86
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS09515
gene id: 880072:DESAC_RS09515
uniprot id: F2NJU0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS05540
gene id: 880072:DESAC_RS05540
uniprot id: F2NCB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

880072:DESAC RS09965
gene id: 880072:DESAC_RS09965
uniprot id: F2NI62
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

880072:DESAC RS11145
gene id: 880072:DESAC_RS11145
uniprot id: F2NFE8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

880072:DESAC RS00690
gene id: 880072:DESAC_RS00690
uniprot id: F2NBV7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

880072:DESAC RS03035
gene id: 880072:DESAC_RS03035
uniprot id: F2NG85
names: Similarity
messages: Belongs to the HepT RNase toxin family.

880072:DESAC RS03260
gene id: 880072:DESAC_RS03260
uniprot id: F2NGC6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

880072:DESAC RS03450
gene id: 880072:DESAC_RS03450
uniprot id: F2NGG2
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS12615
gene id: 880072:DESAC_RS12615
uniprot id: F2NIF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

880072:DESAC RS04820
gene id: 880072:DESAC_RS04820
uniprot id: F2NC44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

880072:DESAC RS01080
gene id: 880072:DESAC_RS01080
uniprot id: F2NEC4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

880072:DESAC RS06955
gene id: 880072:DESAC_RS06955
uniprot id: F2NJ81
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

880072:DESAC RS14400
gene id: 880072:DESAC_RS14400
uniprot id: F2NE55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

880072:DESAC RS07255
gene id: 880072:DESAC_RS07255
uniprot id: F2NJE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

880072:DESAC RS00935
gene id: 880072:DESAC_RS00935
uniprot id: F2NC09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

880072:DESAC RS12140
gene id: 880072:DESAC_RS12140
uniprot id: F2NDI3
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

880072:DESAC RS04610
gene id: 880072:DESAC_RS04610
uniprot id: F2NH27
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS14420
gene id: 880072:DESAC_RS14420
uniprot id: F2NE59
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

880072:DESAC RS11450
gene id: 880072:DESAC_RS11450
uniprot id: F2NFK6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS12995
gene id: 880072:DESAC_RS12995
uniprot id: F2NDT1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

880072:DESAC RS07160
gene id: 880072:DESAC_RS07160
uniprot id: F2NJC1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

880072:DESAC RS14255
gene id: 880072:DESAC_RS14255
uniprot id: F2NIW3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

880072:DESAC RS02390
gene id: 880072:DESAC_RS02390
uniprot id: F2NF26
names: Similarity
messages: Belongs to the P(II) protein family.

880072:DESAC RS06820
gene id: 880072:DESAC_RS06820
uniprot id: F2NHN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

880072:DESAC RS09305
gene id: 880072:DESAC_RS09305
uniprot id: F2NJP9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880072:DESAC RS04670
gene id: 880072:DESAC_RS04670
uniprot id: F2NH40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

880072:DESAC RS08585
gene id: 880072:DESAC_RS08585
uniprot id: F2NCZ1
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

880072:DESAC RS05890
gene id: 880072:DESAC_RS05890
uniprot id: F2NHD2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

880072:DESAC RS12780
gene id: 880072:DESAC_RS12780
uniprot id: F2NII2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880072:DESAC RS05220
gene id: 880072:DESAC_RS05220
uniprot id: F2NH77
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Belongs to the complex I 51 kDa subunit family.

880072:DESAC RS12795
gene id: 880072:DESAC_RS12795
uniprot id: F2NII5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

880072:DESAC RS04175
gene id: 880072:DESAC_RS04175
uniprot id: F2NGU6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS07105
gene id: 880072:DESAC_RS07105
uniprot id: F2NJB0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

880072:DESAC RS02335
gene id: 880072:DESAC_RS02335
uniprot id: F2NF15
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

880072:DESAC RS08530
gene id: 880072:DESAC_RS08530
uniprot id: F2NCY0
names: Similarity
messages: Belongs to the YkuD family.

880072:DESAC RS10585
gene id: 880072:DESAC_RS10585
uniprot id: F2NK14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

880072:DESAC RS15390
gene id: 880072:DESAC_RS15390
uniprot id: F2NFM6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

880072:DESAC RS11375
gene id: 880072:DESAC_RS11375
uniprot id: F2NFJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

880072:DESAC RS09165
gene id: 880072:DESAC_RS09165
uniprot id: F2NJM1
names: Similarity
messages: Belongs to the peptidase S66 family.

880072:DESAC RS00450
gene id: 880072:DESAC_RS00450
uniprot id: F2NJ29
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

880072:DESAC RS10800
gene id: 880072:DESAC_RS10800
uniprot id: F2NDD4
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

880072:DESAC RS09725
gene id: 880072:DESAC_RS09725
uniprot id: F2ND57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS06000
gene id: 880072:DESAC_RS06000
uniprot id: F2NHF3
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS12585
gene id: 880072:DESAC_RS12585
uniprot id: F2NIE5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS14495
gene id: 880072:DESAC_RS14495
uniprot id: F2NE72
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

880072:DESAC RS06585
gene id: 880072:DESAC_RS06585
uniprot id: F2NHJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS03135
gene id: 880072:DESAC_RS03135
uniprot id: F2NGA1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS13190
gene id: 880072:DESAC_RS13190
uniprot id: F2NDW9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

880072:DESAC RS08565
gene id: 880072:DESAC_RS08565
uniprot id: F2NCY7
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

880072:DESAC RS11675
gene id: 880072:DESAC_RS11675
uniprot id: F2NFP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS10100
gene id: 880072:DESAC_RS10100
uniprot id: F2NI89
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

880072:DESAC RS05550
gene id: 880072:DESAC_RS05550
uniprot id: F2NCB7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

880072:DESAC RS11165
gene id: 880072:DESAC_RS11165
uniprot id: F2NFF2
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS15220
gene id: 880072:DESAC_RS15220
uniprot id: F2NCU7
names: Similarity
messages: Belongs to the peptidase C40 family.

880072:DESAC RS14050
gene id: 880072:DESAC_RS14050
uniprot id: F2NIS8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

880072:DESAC RS16450
gene id: 880072:DESAC_RS16450
uniprot id: F2NGQ2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

880072:DESAC RS08515
gene id: 880072:DESAC_RS08515
uniprot id: F2NCX7
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

880072:DESAC RS09170
gene id: 880072:DESAC_RS09170
uniprot id: F2NJM2
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS03730
gene id: 880072:DESAC_RS03730
uniprot id: F2NF77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

880072:DESAC RS12735
gene id: 880072:DESAC_RS12735
uniprot id: F2NIH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS05200
gene id: 880072:DESAC_RS05200
uniprot id: F2NH73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

880072:DESAC RS11695
gene id: 880072:DESAC_RS11695
uniprot id: F2NFQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

880072:DESAC RS16640
gene id: 880072:DESAC_RS16640
uniprot id: F2ND83
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880072:DESAC RS01830
gene id: 880072:DESAC_RS01830
uniprot id: F2NES4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

880072:DESAC RS10005
gene id: 880072:DESAC_RS10005
uniprot id: F2NI70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

880072:DESAC RS00125
gene id: 880072:DESAC_RS00125
uniprot id: F2NGL7
names: Similarity
messages: Belongs to the peptidase S49 family.

880072:DESAC RS05630
gene id: 880072:DESAC_RS05630
uniprot id: F2NCD3
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

880072:DESAC RS03900
gene id: 880072:DESAC_RS03900
uniprot id: F2NFB0
names: Similarity
messages: Belongs to the GSP E family.

880072:DESAC RS11420
gene id: 880072:DESAC_RS11420
uniprot id: F2NFK0
names: Similarity
messages: Belongs to the PhoH family.

880072:DESAC RS03005
gene id: 880072:DESAC_RS03005
uniprot id: F2NG79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

880072:DESAC RS10340
gene id: 880072:DESAC_RS10340
uniprot id: F2NJW4
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS07190
gene id: 880072:DESAC_RS07190
uniprot id: F2NJC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

880072:DESAC RS11160
gene id: 880072:DESAC_RS11160
uniprot id: F2NFF1
names: Function
names: Similarity
messages: Belongs to the CbiK family.
messages: Catalyzes the insertion of Co(2+) into sirohydrochlorin.

880072:DESAC RS13810
gene id: 880072:DESAC_RS13810
uniprot id: F2NE19
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

880072:DESAC RS04455
gene id: 880072:DESAC_RS04455
uniprot id: F2NH01
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880072:DESAC RS10140
gene id: 880072:DESAC_RS10140
uniprot id: F2NI95
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS02605
gene id: 880072:DESAC_RS02605
uniprot id: F2NFZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS10265
gene id: 880072:DESAC_RS10265
uniprot id: F2NJU7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS04970
gene id: 880072:DESAC_RS04970
uniprot id: F2NC76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

880072:DESAC RS04780
gene id: 880072:DESAC_RS04780
uniprot id: F2NC37
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

880072:DESAC RS05095
gene id: 880072:DESAC_RS05095
uniprot id: F2NH53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

880072:DESAC RS12465
gene id: 880072:DESAC_RS12465
uniprot id: F2NIC2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

880072:DESAC RS01590
gene id: 880072:DESAC_RS01590
uniprot id: F2NEM6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

880072:DESAC RS13100
gene id: 880072:DESAC_RS13100
uniprot id: F2NDV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

880072:DESAC RS13125
gene id: 880072:DESAC_RS13125
uniprot id: F2NDV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

880072:DESAC RS05100
gene id: 880072:DESAC_RS05100
uniprot id: F2NH54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

880072:DESAC RS08960
gene id: 880072:DESAC_RS08960
uniprot id: F2NI11
names: Similarity
messages: Belongs to the AAA ATPase family.

880072:DESAC RS05430
gene id: 880072:DESAC_RS05430
uniprot id: F2NHB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

880072:DESAC RS02360
gene id: 880072:DESAC_RS02360
uniprot id: F2NF20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

880072:DESAC RS11130
gene id: 880072:DESAC_RS11130
uniprot id: F2NFE5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

880072:DESAC RS09970
gene id: 880072:DESAC_RS09970
uniprot id: F2NI63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS06580
gene id: 880072:DESAC_RS06580
uniprot id: F2NHJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS01035
gene id: 880072:DESAC_RS01035
uniprot id: F2NEB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

880072:DESAC RS12170
gene id: 880072:DESAC_RS12170
uniprot id: F2NDI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

880072:DESAC RS12575
gene id: 880072:DESAC_RS12575
uniprot id: F2NIE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

880072:DESAC RS05250
gene id: 880072:DESAC_RS05250
uniprot id: F2NH82
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

880072:DESAC RS10710
gene id: 880072:DESAC_RS10710
uniprot id: F2NDB6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS06940
gene id: 880072:DESAC_RS06940
uniprot id: F2NJ77
names: Similarity
messages: Belongs to the phosphohexose mutase family.

880072:DESAC RS03545
gene id: 880072:DESAC_RS03545
uniprot id: F2NGI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

880072:DESAC RS10680
gene id: 880072:DESAC_RS10680
uniprot id: F2NDB1
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

880072:DESAC RS12675
gene id: 880072:DESAC_RS12675
uniprot id: F2NIG3
names: Similarity
messages: Belongs to the universal stress protein A family.

880072:DESAC RS13705
gene id: 880072:DESAC_RS13705
uniprot id: F2NDZ9
names: Similarity
messages: Belongs to the UPF0166 family.

880072:DESAC RS02940
gene id: 880072:DESAC_RS02940
uniprot id: F2NG66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

880072:DESAC RS06895
gene id: 880072:DESAC_RS06895
uniprot id: F2NHQ2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

880072:DESAC RS12670
gene id: 880072:DESAC_RS12670
uniprot id: F2NIG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

880072:DESAC RS10520
gene id: 880072:DESAC_RS10520
uniprot id: F2NK00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880072:DESAC RS15490
gene id: 880072:DESAC_RS15490
uniprot id: F2NE25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

880072:DESAC RS01955
gene id: 880072:DESAC_RS01955
uniprot id: F2NEU4
names: Similarity
messages: Belongs to the universal stress protein A family.

880072:DESAC RS10795
gene id: 880072:DESAC_RS10795
uniprot id: F2NDD3
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

880072:DESAC RS00050
gene id: 880072:DESAC_RS00050
uniprot id: F2NGK2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS05070
gene id: 880072:DESAC_RS05070
uniprot id: F2NH48
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS11990
gene id: 880072:DESAC_RS11990
uniprot id: F2NFW0
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS02070
gene id: 880072:DESAC_RS02070
uniprot id: F2NEW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

880072:DESAC RS05390
gene id: 880072:DESAC_RS05390
uniprot id: F2NHA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

880072:DESAC RS02250
gene id: 880072:DESAC_RS02250
uniprot id: F2NEZ8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

880072:DESAC RS13570
gene id: 880072:DESAC_RS13570
uniprot id: F2NDX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

880072:DESAC RS12905
gene id: 880072:DESAC_RS12905
uniprot id: F2NDR1
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS12385
gene id: 880072:DESAC_RS12385
uniprot id: F2NDN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

880072:DESAC RS12495
gene id: 880072:DESAC_RS12495
uniprot id: F2NIC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

880072:DESAC RS03255
gene id: 880072:DESAC_RS03255
uniprot id: F2NGC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

880072:DESAC RS01310
gene id: 880072:DESAC_RS01310
uniprot id: F2NEG8
names: Subcellular Location Annotation
messages: Cytoplasm

880072:DESAC RS11860
gene id: 880072:DESAC_RS11860
uniprot id: F2NFT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880072:DESAC RS07005
gene id: 880072:DESAC_RS07005
uniprot id: F2NJ91
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

880072:DESAC RS12235
gene id: 880072:DESAC_RS12235
uniprot id: F2NDK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

880072:DESAC RS15985
gene id: 880072:DESAC_RS15985
uniprot id: F2NG54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

880072:DESAC RS13765
gene id: 880072:DESAC_RS13765
uniprot id: F2NE11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880072:DESAC RS04555
gene id: 880072:DESAC_RS04555
uniprot id: F2NH17
names: Similarity
messages: Belongs to the HdrA family.

880072:DESAC RS11485
gene id: 880072:DESAC_RS11485
uniprot id: F2NFL2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

880072:DESAC RS08890
gene id: 880072:DESAC_RS08890
uniprot id: F2NHZ7
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

880072:DESAC RS09325
gene id: 880072:DESAC_RS09325
uniprot id: F2NJQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

880072:DESAC RS03010
gene id: 880072:DESAC_RS03010
uniprot id: F2NG80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

880072:DESAC RS06375
gene id: 880072:DESAC_RS06375
uniprot id: F2NCK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

880072:DESAC RS02540
gene id: 880072:DESAC_RS02540
uniprot id: F2NFY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

880072:DESAC RS02745
gene id: 880072:DESAC_RS02745
uniprot id: F2NG27
names: Similarity
messages: Belongs to the LacAB/RpiB family.

880072:DESAC RS04715
gene id: 880072:DESAC_RS04715
uniprot id: F2NC26
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

880072:DESAC RS14410
gene id: 880072:DESAC_RS14410
uniprot id: F2NE57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

880072:DESAC RS10250
gene id: 880072:DESAC_RS10250
uniprot id: F2NIB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

880072:DESAC RS01585
gene id: 880072:DESAC_RS01585
uniprot id: F2NEM5
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.

880072:DESAC RS00835
gene id: 880072:DESAC_RS00835
uniprot id: F2NBY8
names: Similarity
messages: Belongs to the thioredoxin family.

880072:DESAC RS13750
gene id: 880072:DESAC_RS13750
uniprot id: F2NE08
names: Similarity
messages: Belongs to the CinA family.

880072:DESAC RS00745
gene id: 880072:DESAC_RS00745
uniprot id: F2NBX0
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

880072:DESAC RS04235
gene id: 880072:DESAC_RS04235
uniprot id: F2NGV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

880072:DESAC RS05865
gene id: 880072:DESAC_RS05865
uniprot id: F2NHC8
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

880072:DESAC RS05805
gene id: 880072:DESAC_RS05805
uniprot id: F2NHB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

880072:DESAC RS06740
gene id: 880072:DESAC_RS06740
uniprot id: F2NHM1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

880072:DESAC RS06785
gene id: 880072:DESAC_RS06785
uniprot id: F2NHN0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

880072:DESAC RS10550
gene id: 880072:DESAC_RS10550
uniprot id: F2NK06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

880072:DESAC RS03205
gene id: 880072:DESAC_RS03205
uniprot id: F2NGB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

880072:DESAC RS14660
gene id: 880072:DESAC_RS14660
uniprot id: F2NEA3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

880072:DESAC RS09920
gene id: 880072:DESAC_RS09920
uniprot id: F2NI52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

880072:DESAC RS03950
gene id: 880072:DESAC_RS03950
uniprot id: F2NGQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

880072:DESAC RS15380
gene id: 880072:DESAC_RS15380
uniprot id: F2NFH7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

880072:DESAC RS03665
gene id: 880072:DESAC_RS03665
uniprot id: F2NF64
names: Similarity
messages: Belongs to the archease family.

880072:DESAC RS07020
gene id: 880072:DESAC_RS07020
uniprot id: F2NJ94
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

880072:DESAC RS06800
gene id: 880072:DESAC_RS06800
uniprot id: F2NHN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

880072:DESAC RS12165
gene id: 880072:DESAC_RS12165
uniprot id: F2NDI8
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS04720
gene id: 880072:DESAC_RS04720
uniprot id: F2NC27
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS08750
gene id: 880072:DESAC_RS08750
uniprot id: F2ND22
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS12660
gene id: 880072:DESAC_RS12660
uniprot id: F2NIG0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

880072:DESAC RS01230
gene id: 880072:DESAC_RS01230
uniprot id: F2NEF3
names: Similarity
messages: Belongs to the peptidase C56 family.

880072:DESAC RS08080
gene id: 880072:DESAC_RS08080
uniprot id: F2NJG3
names: Similarity
messages: Belongs to the peptidase M16 family.

880072:DESAC RS04625
gene id: 880072:DESAC_RS04625
uniprot id: F2NH31
names: Similarity
messages: Belongs to the asparagine synthetase family.

880072:DESAC RS11920
gene id: 880072:DESAC_RS11920
uniprot id: F2NFU6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

880072:DESAC RS13135
gene id: 880072:DESAC_RS13135
uniprot id: F2NDV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS06810
gene id: 880072:DESAC_RS06810
uniprot id: F2NHN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

880072:DESAC RS14130
gene id: 880072:DESAC_RS14130
uniprot id: F2NIU4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

880072:DESAC RS03175
gene id: 880072:DESAC_RS03175
uniprot id: F2NGA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

880072:DESAC RS15135
gene id: 880072:DESAC_RS15135
uniprot id: F2NHE7
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

880072:DESAC RS11305
gene id: 880072:DESAC_RS11305
uniprot id: F2NFH8
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS14500
gene id: 880072:DESAC_RS14500
uniprot id: F2NE73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

880072:DESAC RS08725
gene id: 880072:DESAC_RS08725
uniprot id: F2ND17
names: Similarity
messages: Belongs to the LarC family.

880072:DESAC RS05285
gene id: 880072:DESAC_RS05285
uniprot id: F2NH89
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

880072:DESAC RS08865
gene id: 880072:DESAC_RS08865
uniprot id: F2NHZ2
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

880072:DESAC RS01740
gene id: 880072:DESAC_RS01740
uniprot id: F2NEQ7
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

880072:DESAC RS04150
gene id: 880072:DESAC_RS04150
uniprot id: F2NGU1
names: Similarity
messages: Belongs to the HdrA family.

880072:DESAC RS11415
gene id: 880072:DESAC_RS11415
uniprot id: F2NFJ9
names: Similarity
messages: Belongs to the peptidase M16 family.

880072:DESAC RS11715
gene id: 880072:DESAC_RS11715
uniprot id: F2NFQ6
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS14915
gene id: 880072:DESAC_RS14915
uniprot id: F2NEU2
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS12390
gene id: 880072:DESAC_RS12390
uniprot id: F2NDN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS05385
gene id: 880072:DESAC_RS05385
uniprot id: F2NHA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

880072:DESAC RS12570
gene id: 880072:DESAC_RS12570
uniprot id: F2NIE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

880072:DESAC RS07080
gene id: 880072:DESAC_RS07080
uniprot id: F2NJA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

880072:DESAC RS01055
gene id: 880072:DESAC_RS01055
uniprot id: F2NEB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

880072:DESAC RS07615
gene id: 880072:DESAC_RS07615
uniprot id: F2NCV2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880072:DESAC RS09760
gene id: 880072:DESAC_RS09760
uniprot id: F2ND65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

880072:DESAC RS07325
gene id: 880072:DESAC_RS07325
uniprot id: F2NCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

880072:DESAC RS11760
gene id: 880072:DESAC_RS11760
uniprot id: F2NFR5
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS07045
gene id: 880072:DESAC_RS07045
uniprot id: F2NJ99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

880072:DESAC RS13360
gene id: 880072:DESAC_RS13360
uniprot id: F2NIM5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880072:DESAC RS02055
gene id: 880072:DESAC_RS02055
uniprot id: F2NEW3
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS06180
gene id: 880072:DESAC_RS06180
uniprot id: F2NCH0
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

880072:DESAC RS13480
gene id: 880072:DESAC_RS13480
uniprot id: F2NIP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

880072:DESAC RS07130
gene id: 880072:DESAC_RS07130
uniprot id: F2NJB5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

880072:DESAC RS15005
gene id: 880072:DESAC_RS15005
uniprot id: F2NF91
names: Similarity
messages: Belongs to the transglycosylase Slt family.

880072:DESAC RS11315
gene id: 880072:DESAC_RS11315
uniprot id: F2NFI0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

880072:DESAC RS03280
gene id: 880072:DESAC_RS03280
uniprot id: F2NGD0
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS10360
gene id: 880072:DESAC_RS10360
uniprot id: F2NJW8
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS08730
gene id: 880072:DESAC_RS08730
uniprot id: F2ND18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

880072:DESAC RS14060
gene id: 880072:DESAC_RS14060
uniprot id: F2NIT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

880072:DESAC RS11615
gene id: 880072:DESAC_RS11615
uniprot id: F2NFN7
names: Similarity
messages: Belongs to the aspartokinase family.

880072:DESAC RS02795
gene id: 880072:DESAC_RS02795
uniprot id: F2NG37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS02770
gene id: 880072:DESAC_RS02770
uniprot id: F2NG32
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

880072:DESAC RS03655
gene id: 880072:DESAC_RS03655
uniprot id: F2NF62
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

880072:DESAC RS04165
gene id: 880072:DESAC_RS04165
uniprot id: F2NGU4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

880072:DESAC RS12330
gene id: 880072:DESAC_RS12330
uniprot id: F2NDM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

880072:DESAC RS05400
gene id: 880072:DESAC_RS05400
uniprot id: F2NHB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

880072:DESAC RS14795
gene id: 880072:DESAC_RS14795
uniprot id: F2NIZ5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

880072:DESAC RS00860
gene id: 880072:DESAC_RS00860
uniprot id: F2NBZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

880072:DESAC RS07585
gene id: 880072:DESAC_RS07585
uniprot id: F2NCU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS08090
gene id: 880072:DESAC_RS08090
uniprot id: F2NJG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

880072:DESAC RS06600
gene id: 880072:DESAC_RS06600
uniprot id: F2NHJ6
names: Similarity
messages: Belongs to the Skp family.

880072:DESAC RS07215
gene id: 880072:DESAC_RS07215
uniprot id: F2NJD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

880072:DESAC RS01730
gene id: 880072:DESAC_RS01730
uniprot id: F2NEQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

880072:DESAC RS03325
gene id: 880072:DESAC_RS03325
uniprot id: F2NGE0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

880072:DESAC RS10885
gene id: 880072:DESAC_RS10885
uniprot id: F2NDF1
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

880072:DESAC RS10575
gene id: 880072:DESAC_RS10575
uniprot id: F2NK12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

880072:DESAC RS01680
gene id: 880072:DESAC_RS01680
uniprot id: F2NEP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

880072:DESAC RS02255
gene id: 880072:DESAC_RS02255
uniprot id: F2NEZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

880072:DESAC RS02500
gene id: 880072:DESAC_RS02500
uniprot id: F2NF48
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

880072:DESAC RS01200
gene id: 880072:DESAC_RS01200
uniprot id: F2NEE7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

880072:DESAC RS06450
gene id: 880072:DESAC_RS06450
uniprot id: F2NCM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

880072:DESAC RS13215
gene id: 880072:DESAC_RS13215
uniprot id: F2NIJ7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

880072:DESAC RS11195
gene id: 880072:DESAC_RS11195
uniprot id: F2NFF7
names: Similarity
messages: Belongs to the histone deacetylase family.

880072:DESAC RS12215
gene id: 880072:DESAC_RS12215
uniprot id: F2NDJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

880072:DESAC RS09840
gene id: 880072:DESAC_RS09840
uniprot id: F2ND82
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

880072:DESAC RS11705
gene id: 880072:DESAC_RS11705
uniprot id: F2NFQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

880072:DESAC RS11435
gene id: 880072:DESAC_RS11435
uniprot id: F2NFK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

880072:DESAC RS10670
gene id: 880072:DESAC_RS10670
uniprot id: F2NDA9
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS04135
gene id: 880072:DESAC_RS04135
uniprot id: F2NGT8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

880072:DESAC RS00190
gene id: 880072:DESAC_RS00190
uniprot id: F2NGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS13195
gene id: 880072:DESAC_RS13195
uniprot id: F2NIJ3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

880072:DESAC RS00375
gene id: 880072:DESAC_RS00375
uniprot id: F2NJ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HsdR family.
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS05770
gene id: 880072:DESAC_RS05770
uniprot id: F2NCG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

880072:DESAC RS08350
gene id: 880072:DESAC_RS08350
uniprot id: F2NJL2
names: Similarity
messages: Belongs to the class-I fumarase family.

880072:DESAC RS10590
gene id: 880072:DESAC_RS10590
uniprot id: F2NK15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

880072:DESAC RS04950
gene id: 880072:DESAC_RS04950
uniprot id: F2NC72
names: Similarity
messages: Belongs to the peptidase S16 family.

880072:DESAC RS07050
gene id: 880072:DESAC_RS07050
uniprot id: F2NJA0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS10730
gene id: 880072:DESAC_RS10730
uniprot id: F2NDC0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

880072:DESAC RS05120
gene id: 880072:DESAC_RS05120
uniprot id: F2NH58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

880072:DESAC RS09835
gene id: 880072:DESAC_RS09835
uniprot id: F2ND81
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

880072:DESAC RS03385
gene id: 880072:DESAC_RS03385
uniprot id: F2NGF2
names: Similarity
messages: Belongs to the ycf81 family.

880072:DESAC RS08955
gene id: 880072:DESAC_RS08955
uniprot id: F2NI10
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

880072:DESAC RS12665
gene id: 880072:DESAC_RS12665
uniprot id: F2NIG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

880072:DESAC RS10400
gene id: 880072:DESAC_RS10400
uniprot id: F2NJX6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

880072:DESAC RS12240
gene id: 880072:DESAC_RS12240
uniprot id: F2NDK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

880072:DESAC RS12055
gene id: 880072:DESAC_RS12055
uniprot id: F2NFX5
names: Similarity
messages: Belongs to the HypE family.

880072:DESAC RS05090
gene id: 880072:DESAC_RS05090
uniprot id: F2NH52
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

880072:DESAC RS10105
gene id: 880072:DESAC_RS10105
uniprot id: F2NI90
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

880072:DESAC RS08360
gene id: 880072:DESAC_RS08360
uniprot id: F2NJL4
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

880072:DESAC RS11755
gene id: 880072:DESAC_RS11755
uniprot id: F2NFR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS14910
gene id: 880072:DESAC_RS14910
uniprot id: F2NEK2
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS04870
gene id: 880072:DESAC_RS04870
uniprot id: F2NC56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

880072:DESAC RS10725
gene id: 880072:DESAC_RS10725
uniprot id: F2NDB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

880072:DESAC RS09210
gene id: 880072:DESAC_RS09210
uniprot id: F2NJN0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

880072:DESAC RS07205
gene id: 880072:DESAC_RS07205
uniprot id: F2NJD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

880072:DESAC RS01885
gene id: 880072:DESAC_RS01885
uniprot id: F2NET2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

880072:DESAC RS14625
gene id: 880072:DESAC_RS14625
uniprot id: F2NE95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

880072:DESAC RS13430
gene id: 880072:DESAC_RS13430
uniprot id: F2NIP0
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

880072:DESAC RS04885
gene id: 880072:DESAC_RS04885
uniprot id: F2NC59
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880072:DESAC RS01305
gene id: 880072:DESAC_RS01305
uniprot id: F2NEG7
names: Similarity
messages: Belongs to the YggT family.

880072:DESAC RS11580
gene id: 880072:DESAC_RS11580
uniprot id: F2NFN0
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

880072:DESAC RS00490
gene id: 880072:DESAC_RS00490
uniprot id: F2NJ37
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

880072:DESAC RS09645
gene id: 880072:DESAC_RS09645
uniprot id: F2ND44
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

880072:DESAC RS05530
gene id: 880072:DESAC_RS05530
uniprot id: F2NCB3
names: Similarity
messages: Belongs to the peptidase S58 family.

880072:DESAC RS07240
gene id: 880072:DESAC_RS07240
uniprot id: F2NJD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

880072:DESAC RS00760
gene id: 880072:DESAC_RS00760
uniprot id: F2NBX3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

880072:DESAC RS03615
gene id: 880072:DESAC_RS03615
uniprot id: F2NF54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

880072:DESAC RS05670
gene id: 880072:DESAC_RS05670
uniprot id: F2NCE1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

880072:DESAC RS07145
gene id: 880072:DESAC_RS07145
uniprot id: F2NJB8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880072:DESAC RS07990
gene id: 880072:DESAC_RS07990
uniprot id: F2NHX3
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

880072:DESAC RS01650
gene id: 880072:DESAC_RS01650
uniprot id: F2NEN9
names: Similarity
messages: Belongs to the UPF0751 family.

880072:DESAC RS14610
gene id: 880072:DESAC_RS14610
uniprot id: F2NE92
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS09455
gene id: 880072:DESAC_RS09455
uniprot id: F2NJS8
names: Similarity
messages: Belongs to the FeoA family.

880072:DESAC RS11405
gene id: 880072:DESAC_RS11405
uniprot id: F2NFJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

880072:DESAC RS08365
gene id: 880072:DESAC_RS08365
uniprot id: F2NJL5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

880072:DESAC RS07820
gene id: 880072:DESAC_RS07820
uniprot id: F2NHU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

880072:DESAC RS06350
gene id: 880072:DESAC_RS06350
uniprot id: F2NCK0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

880072:DESAC RS12595
gene id: 880072:DESAC_RS12595
uniprot id: F2NIE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

880072:DESAC RS02410
gene id: 880072:DESAC_RS02410
uniprot id: F2NF30
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS08130
gene id: 880072:DESAC_RS08130
uniprot id: F2NJH2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

880072:DESAC RS11655
gene id: 880072:DESAC_RS11655
uniprot id: F2NFP4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

880072:DESAC RS10490
gene id: 880072:DESAC_RS10490
uniprot id: F2NJZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880072:DESAC RS03190
gene id: 880072:DESAC_RS03190
uniprot id: F2NGB2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880072:DESAC RS05800
gene id: 880072:DESAC_RS05800
uniprot id: F2NCG7
names: Similarity
messages: Belongs to the catalase family.

880072:DESAC RS12565
gene id: 880072:DESAC_RS12565
uniprot id: F2NIE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

880072:DESAC RS07150
gene id: 880072:DESAC_RS07150
uniprot id: F2NJB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

880072:DESAC RS12180
gene id: 880072:DESAC_RS12180
uniprot id: F2NDJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

880072:DESAC RS13235
gene id: 880072:DESAC_RS13235
uniprot id: F2NIK1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

880072:DESAC RS06285
gene id: 880072:DESAC_RS06285
uniprot id: F2NCJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS11600
gene id: 880072:DESAC_RS11600
uniprot id: F2NFN5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

880072:DESAC RS12580
gene id: 880072:DESAC_RS12580
uniprot id: F2NIE4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

880072:DESAC RS05245
gene id: 880072:DESAC_RS05245
uniprot id: F2NH81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

880072:DESAC RS12750
gene id: 880072:DESAC_RS12750
uniprot id: F2NIH6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

880072:DESAC RS05110
gene id: 880072:DESAC_RS05110
uniprot id: F2NH56
names: Similarity
messages: Belongs to the peptidase M16 family.

880072:DESAC RS07575
gene id: 880072:DESAC_RS07575
uniprot id: F2NCU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

880072:DESAC RS03200
gene id: 880072:DESAC_RS03200
uniprot id: F2NGB4
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS02845
gene id: 880072:DESAC_RS02845
uniprot id: F2NG48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

880072:DESAC RS05720
gene id: 880072:DESAC_RS05720
uniprot id: F2NCF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

880072:DESAC RS04160
gene id: 880072:DESAC_RS04160
uniprot id: F2NGU3
names: Similarity
messages: Belongs to the HdrA family.

880072:DESAC RS14895
gene id: 880072:DESAC_RS14895
uniprot id: F2NEI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880072:DESAC RS10135
gene id: 880072:DESAC_RS10135
uniprot id: F2NI94
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

880072:DESAC RS12275
gene id: 880072:DESAC_RS12275
uniprot id: F2NDL0
names: Similarity
messages: Belongs to the YkuD family.

880072:DESAC RS06140
gene id: 880072:DESAC_RS06140
uniprot id: F2NHH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

880072:DESAC RS04190
gene id: 880072:DESAC_RS04190
uniprot id: F2NGU9
names: Similarity
messages: Belongs to the RemA family.

880072:DESAC RS00015
gene id: 880072:DESAC_RS00015
uniprot id: F2NGJ5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

880072:DESAC RS12510
gene id: 880072:DESAC_RS12510
uniprot id: F2NIC9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

880072:DESAC RS07610
gene id: 880072:DESAC_RS07610
uniprot id: F2NCV1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880072:DESAC RS10435
gene id: 880072:DESAC_RS10435
uniprot id: F2NJY3
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

880072:DESAC RS01750
gene id: 880072:DESAC_RS01750
uniprot id: F2NEQ9
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

880072:DESAC RS10055
gene id: 880072:DESAC_RS10055
uniprot id: F2NI80
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS06575
gene id: 880072:DESAC_RS06575
uniprot id: F2NHJ1
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS05420
gene id: 880072:DESAC_RS05420
uniprot id: F2NHB3
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS06830
gene id: 880072:DESAC_RS06830
uniprot id: F2NHN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880072:DESAC RS04210
gene id: 880072:DESAC_RS04210
uniprot id: F2NGV3
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

880072:DESAC RS08965
gene id: 880072:DESAC_RS08965
uniprot id: F2NI12
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

880072:DESAC RS10525
gene id: 880072:DESAC_RS10525
uniprot id: F2NK01
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Belongs to the complex I 51 kDa subunit family.

880072:DESAC RS13755
gene id: 880072:DESAC_RS13755
uniprot id: F2NE09
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

880072:DESAC RS01490
gene id: 880072:DESAC_RS01490
uniprot id: F2NEK5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

880072:DESAC RS13375
gene id: 880072:DESAC_RS13375
uniprot id: F2NIM8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS11105
gene id: 880072:DESAC_RS11105
uniprot id: F2NFE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

880072:DESAC RS07305
gene id: 880072:DESAC_RS07305
uniprot id: F2NCP1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

880072:DESAC RS01835
gene id: 880072:DESAC_RS01835
uniprot id: F2NES5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

880072:DESAC RS09370
gene id: 880072:DESAC_RS09370
uniprot id: F2NJR1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

880072:DESAC RS06085
gene id: 880072:DESAC_RS06085
uniprot id: F2NHH0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

880072:DESAC RS13515
gene id: 880072:DESAC_RS13515
uniprot id: F2NIQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

880072:DESAC RS02900
gene id: 880072:DESAC_RS02900
uniprot id: F2NG58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

880072:DESAC RS08575
gene id: 880072:DESAC_RS08575
uniprot id: F2NCY9
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

880072:DESAC RS01095
gene id: 880072:DESAC_RS01095
uniprot id: F2NEC7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

880072:DESAC RS12300
gene id: 880072:DESAC_RS12300
uniprot id: F2NDL5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

880072:DESAC RS08425
gene id: 880072:DESAC_RS08425
uniprot id: F2NCW4
names: Subcellular Location Annotation
messages: Periplasm

880072:DESAC RS12710
gene id: 880072:DESAC_RS12710
uniprot id: F2NIG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

880072:DESAC RS03525
gene id: 880072:DESAC_RS03525
uniprot id: F2NGH8
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

880072:DESAC RS10695
gene id: 880072:DESAC_RS10695
uniprot id: F2NDB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS08105
gene id: 880072:DESAC_RS08105
uniprot id: F2NJG8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

880072:DESAC RS03725
gene id: 880072:DESAC_RS03725
uniprot id: F2NF76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

880072:DESAC RS00780
gene id: 880072:DESAC_RS00780
uniprot id: F2NBX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

880072:DESAC RS04030
gene id: 880072:DESAC_RS04030
uniprot id: F2NGR9
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

880072:DESAC RS07840
gene id: 880072:DESAC_RS07840
uniprot id: F2NHU5
names: Similarity
messages: Belongs to the histone deacetylase family.

880072:DESAC RS07235
gene id: 880072:DESAC_RS07235
uniprot id: F2NJD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

880072:DESAC RS10410
gene id: 880072:DESAC_RS10410
uniprot id: F2NJX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

880072:DESAC RS11500
gene id: 880072:DESAC_RS11500
uniprot id: F2NFL5
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

880072:DESAC RS09785
gene id: 880072:DESAC_RS09785
uniprot id: F2ND71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

880072:DESAC RS03890
gene id: 880072:DESAC_RS03890
uniprot id: F2NFA8
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS07260
gene id: 880072:DESAC_RS07260
uniprot id: F2NCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

880072:DESAC RS06590
gene id: 880072:DESAC_RS06590
uniprot id: F2NHJ4
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS05555
gene id: 880072:DESAC_RS05555
uniprot id: F2NCB8
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS02370
gene id: 880072:DESAC_RS02370
uniprot id: F2NF22
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

880072:DESAC RS06055
gene id: 880072:DESAC_RS06055
uniprot id: F2NHG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS12835
gene id: 880072:DESAC_RS12835
uniprot id: F2NDP8
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

880072:DESAC RS08430
gene id: 880072:DESAC_RS08430
uniprot id: F2NCW5
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

880072:DESAC RS03925
gene id: 880072:DESAC_RS03925
uniprot id: F2NFB5
names: Similarity
messages: Belongs to the peptidase A24 family.

880072:DESAC RS12550
gene id: 880072:DESAC_RS12550
uniprot id: F2NID7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

880072:DESAC RS06010
gene id: 880072:DESAC_RS06010
uniprot id: F2NHF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880072:DESAC RS02885
gene id: 880072:DESAC_RS02885
uniprot id: F2NG55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

880072:DESAC RS04325
gene id: 880072:DESAC_RS04325
uniprot id: F2NGX5
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS08570
gene id: 880072:DESAC_RS08570
uniprot id: F2NCY8
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

880072:DESAC RS10355
gene id: 880072:DESAC_RS10355
uniprot id: F2NJW7
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS11295
gene id: 880072:DESAC_RS11295
uniprot id: F2NFH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

880072:DESAC RS14815
gene id: 880072:DESAC_RS14815
uniprot id: F2NIZ7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

880072:DESAC RS14365
gene id: 880072:DESAC_RS14365
uniprot id: F2NE48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS01435
gene id: 880072:DESAC_RS01435
uniprot id: F2NEJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

880072:DESAC RS07605
gene id: 880072:DESAC_RS07605
uniprot id: F2NCV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

880072:DESAC RS06045
gene id: 880072:DESAC_RS06045
uniprot id: F2NHG2
names: Similarity
messages: Belongs to the peptidase S16 family.

880072:DESAC RS15085
gene id: 880072:DESAC_RS15085
uniprot id: F2NC91
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880072:DESAC RS03895
gene id: 880072:DESAC_RS03895
uniprot id: F2NFA9
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS02530
gene id: 880072:DESAC_RS02530
uniprot id: F2NFY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

880072:DESAC RS13175
gene id: 880072:DESAC_RS13175
uniprot id: F2NDW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

880072:DESAC RS02285
gene id: 880072:DESAC_RS02285
uniprot id: F2NF05
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

880072:DESAC RS01960
gene id: 880072:DESAC_RS01960
uniprot id: F2NEU5
names: Similarity
messages: Belongs to the Ahb/Nir family.

880072:DESAC RS01520
gene id: 880072:DESAC_RS01520
uniprot id: F2NEL2
names: Similarity
messages: Belongs to the HdrA family.

880072:DESAC RS08120
gene id: 880072:DESAC_RS08120
uniprot id: F2NJH1
names: Similarity
messages: Belongs to the universal stress protein A family.

880072:DESAC RS12745
gene id: 880072:DESAC_RS12745
uniprot id: F2NIH5
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS13200
gene id: 880072:DESAC_RS13200
uniprot id: F2NIJ4
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS11625
gene id: 880072:DESAC_RS11625
uniprot id: F2NFN8
names: Similarity
messages: Belongs to the UPF0758 family.

880072:DESAC RS13615
gene id: 880072:DESAC_RS13615
uniprot id: F2NDY1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

880072:DESAC RS05075
gene id: 880072:DESAC_RS05075
uniprot id: F2NH49
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

880072:DESAC RS05910
gene id: 880072:DESAC_RS05910
uniprot id: F2NHD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

880072:DESAC RS12315
gene id: 880072:DESAC_RS12315
uniprot id: F2NDL8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

880072:DESAC RS03690
gene id: 880072:DESAC_RS03690
uniprot id: F2NF69
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

880072:DESAC RS03025
gene id: 880072:DESAC_RS03025
uniprot id: F2NG83
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

880072:DESAC RS00390
gene id: 880072:DESAC_RS00390
uniprot id: F2NJ18
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880072:DESAC RS02920
gene id: 880072:DESAC_RS02920
uniprot id: F2NG62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

880072:DESAC RS02045
gene id: 880072:DESAC_RS02045
uniprot id: F2NEW1
names: Subcellular Location Annotation
messages: Cell outer membrane

880072:DESAC RS10040
gene id: 880072:DESAC_RS10040
uniprot id: F2NI77
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

880072:DESAC RS14350
gene id: 880072:DESAC_RS14350
uniprot id: F2NE45
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

880072:DESAC RS08925
gene id: 880072:DESAC_RS08925
uniprot id: F2NI04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

880072:DESAC RS07965
gene id: 880072:DESAC_RS07965
uniprot id: F2NHX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

880072:DESAC RS06625
gene id: 880072:DESAC_RS06625
uniprot id: F2NHK1
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS13590
gene id: 880072:DESAC_RS13590
uniprot id: F2NDX6
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS12360
gene id: 880072:DESAC_RS12360
uniprot id: F2NDM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

880072:DESAC RS03685
gene id: 880072:DESAC_RS03685
uniprot id: F2NF68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

880072:DESAC RS07300
gene id: 880072:DESAC_RS07300
uniprot id: F2NCP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

880072:DESAC RS02340
gene id: 880072:DESAC_RS02340
uniprot id: F2NF16
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS06265
gene id: 880072:DESAC_RS06265
uniprot id: F2NCI6
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

880072:DESAC RS11225
gene id: 880072:DESAC_RS11225
uniprot id: F2NFG2
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

880072:DESAC RS06555
gene id: 880072:DESAC_RS06555
uniprot id: F2NHI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

880072:DESAC RS10190
gene id: 880072:DESAC_RS10190
uniprot id: F2NIA6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

880072:DESAC RS14695
gene id: 880072:DESAC_RS14695
uniprot id: F2NIX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

880072:DESAC RS11665
gene id: 880072:DESAC_RS11665
uniprot id: F2NFP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

880072:DESAC RS07135
gene id: 880072:DESAC_RS07135
uniprot id: F2NJB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

880072:DESAC RS00215
gene id: 880072:DESAC_RS00215
uniprot id: F2NGN5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

880072:DESAC RS06135
gene id: 880072:DESAC_RS06135
uniprot id: F2NHH8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880072:DESAC RS09215
gene id: 880072:DESAC_RS09215
uniprot id: F2NJN1
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS13735
gene id: 880072:DESAC_RS13735
uniprot id: F2NE05
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

880072:DESAC RS08490
gene id: 880072:DESAC_RS08490
uniprot id: F2NCX4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

880072:DESAC RS03945
gene id: 880072:DESAC_RS03945
uniprot id: F2NGQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

880072:DESAC RS10220
gene id: 880072:DESAC_RS10220
uniprot id: F2NIB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS12175
gene id: 880072:DESAC_RS12175
uniprot id: F2NDJ0
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS13490
gene id: 880072:DESAC_RS13490
uniprot id: F2NIQ0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

880072:DESAC RS15120
gene id: 880072:DESAC_RS15120
uniprot id: F2NHC9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

880072:DESAC RS13130
gene id: 880072:DESAC_RS13130
uniprot id: F2NDV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

880072:DESAC RS11740
gene id: 880072:DESAC_RS11740
uniprot id: F2NFR1
names: Similarity
messages: Belongs to the UPF0045 family.

880072:DESAC RS09100
gene id: 880072:DESAC_RS09100
uniprot id: F2NI37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

880072:DESAC RS04570
gene id: 880072:DESAC_RS04570
uniprot id: F2NH20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

880072:DESAC RS00850
gene id: 880072:DESAC_RS00850
uniprot id: F2NBZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

880072:DESAC RS04215
gene id: 880072:DESAC_RS04215
uniprot id: F2NGV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

880072:DESAC RS08710
gene id: 880072:DESAC_RS08710
uniprot id: F2ND15
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS00930
gene id: 880072:DESAC_RS00930
uniprot id: F2NC08
names: Subunit
messages: Heterodimer of a large and a small subunit.

880072:DESAC RS14005
gene id: 880072:DESAC_RS14005
uniprot id: F2NIR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

880072:DESAC RS03220
gene id: 880072:DESAC_RS03220
uniprot id: F2NGB8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS01335
gene id: 880072:DESAC_RS01335
uniprot id: F2NEH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

880072:DESAC RS12690
gene id: 880072:DESAC_RS12690
uniprot id: F2NIG6
names: Similarity
messages: Belongs to the universal stress protein A family.

880072:DESAC RS01850
gene id: 880072:DESAC_RS01850
uniprot id: F2NES8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

880072:DESAC RS13520
gene id: 880072:DESAC_RS13520
uniprot id: F2NIQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

880072:DESAC RS03330
gene id: 880072:DESAC_RS03330
uniprot id: F2NGE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

880072:DESAC RS02700
gene id: 880072:DESAC_RS02700
uniprot id: F2NG17
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

880072:DESAC RS00570
gene id: 880072:DESAC_RS00570
uniprot id: F2NJ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

880072:DESAC RS08050
gene id: 880072:DESAC_RS08050
uniprot id: F2NJF6
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

880072:DESAC RS01155
gene id: 880072:DESAC_RS01155
uniprot id: F2NED8
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS05515
gene id: 880072:DESAC_RS05515
uniprot id: F2NCB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

880072:DESAC RS05195
gene id: 880072:DESAC_RS05195
uniprot id: F2NH72
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS06780
gene id: 880072:DESAC_RS06780
uniprot id: F2NHM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS05785
gene id: 880072:DESAC_RS05785
uniprot id: F2NCG4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

880072:DESAC RS02600
gene id: 880072:DESAC_RS02600
uniprot id: F2NFZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

880072:DESAC RS01990
gene id: 880072:DESAC_RS01990
uniprot id: F2NEV1
names: Similarity
messages: Belongs to the disproportionating enzyme family.

880072:DESAC RS14600
gene id: 880072:DESAC_RS14600
uniprot id: F2NE90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

880072:DESAC RS00155
gene id: 880072:DESAC_RS00155
uniprot id: F2NGM3
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS10485
gene id: 880072:DESAC_RS10485
uniprot id: F2NJZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880072:DESAC RS06295
gene id: 880072:DESAC_RS06295
uniprot id: F2NCJ2
names: Similarity
messages: Belongs to the universal stress protein A family.

880072:DESAC RS04245
gene id: 880072:DESAC_RS04245
uniprot id: F2NGW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

880072:DESAC RS03660
gene id: 880072:DESAC_RS03660
uniprot id: F2NF63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

880072:DESAC RS14215
gene id: 880072:DESAC_RS14215
uniprot id: F2NIV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

880072:DESAC RS12470
gene id: 880072:DESAC_RS12470
uniprot id: F2NIC3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

880072:DESAC RS02715
gene id: 880072:DESAC_RS02715
uniprot id: F2NG21
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

880072:DESAC RS11275
gene id: 880072:DESAC_RS11275
uniprot id: F2NFH1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

880072:DESAC RS12440
gene id: 880072:DESAC_RS12440
uniprot id: F2NDP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

880072:DESAC RS02780
gene id: 880072:DESAC_RS02780
uniprot id: F2NG34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

880072:DESAC RS12025
gene id: 880072:DESAC_RS12025
uniprot id: F2NFW9
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS01375
gene id: 880072:DESAC_RS01375
uniprot id: F2NEI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

880072:DESAC RS06985
gene id: 880072:DESAC_RS06985
uniprot id: F2NJ87
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880072:DESAC RS08980
gene id: 880072:DESAC_RS08980
uniprot id: F2NI15
names: Similarity
messages: Belongs to the CFA/CMAS family.

880072:DESAC RS00005
gene id: 880072:DESAC_RS00005
uniprot id: F2NGJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

880072:DESAC RS10415
gene id: 880072:DESAC_RS10415
uniprot id: F2NJX9
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

880072:DESAC RS14220
gene id: 880072:DESAC_RS14220
uniprot id: F2NIV5
names: Similarity
messages: Belongs to the FrmR/RcnR family.

880072:DESAC RS08950
gene id: 880072:DESAC_RS08950
uniprot id: F2NI09
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

880072:DESAC RS06150
gene id: 880072:DESAC_RS06150
uniprot id: F2NHI2
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS11085
gene id: 880072:DESAC_RS11085
uniprot id: F2NFD6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

880072:DESAC RS11480
gene id: 880072:DESAC_RS11480
uniprot id: F2NFL1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

880072:DESAC RS11950
gene id: 880072:DESAC_RS11950
uniprot id: F2NFV2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

880072:DESAC RS03715
gene id: 880072:DESAC_RS03715
uniprot id: F2NF74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

880072:DESAC RS00115
gene id: 880072:DESAC_RS00115
uniprot id: F2NGL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

880072:DESAC RS10080
gene id: 880072:DESAC_RS10080
uniprot id: F2NI85
names: Similarity
messages: Belongs to the leucine-binding protein family.

880072:DESAC RS05990
gene id: 880072:DESAC_RS05990
uniprot id: F2NHF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880072:DESAC RS02290
gene id: 880072:DESAC_RS02290
uniprot id: F2NF06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

880072:DESAC RS06745
gene id: 880072:DESAC_RS06745
uniprot id: F2NHM2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

880072:DESAC RS00845
gene id: 880072:DESAC_RS00845
uniprot id: F2NBZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

880072:DESAC RS07220
gene id: 880072:DESAC_RS07220
uniprot id: F2NJD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

880072:DESAC RS02750
gene id: 880072:DESAC_RS02750
uniprot id: F2NG28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS10405
gene id: 880072:DESAC_RS10405
uniprot id: F2NJX7
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS11045
gene id: 880072:DESAC_RS11045
uniprot id: F2NFC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

880072:DESAC RS03215
gene id: 880072:DESAC_RS03215
uniprot id: F2NGB7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS05150
gene id: 880072:DESAC_RS05150
uniprot id: F2NH64
names: Similarity
messages: Belongs to the glutamine synthetase family.

880072:DESAC RS00035
gene id: 880072:DESAC_RS00035
uniprot id: F2NGJ9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

880072:DESAC RS04980
gene id: 880072:DESAC_RS04980
uniprot id: F2NC78
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

880072:DESAC RS04840
gene id: 880072:DESAC_RS04840
uniprot id: F2NC48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

880072:DESAC RS12190
gene id: 880072:DESAC_RS12190
uniprot id: F2NDJ3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

880072:DESAC RS14545
gene id: 880072:DESAC_RS14545
uniprot id: F2NE82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

880072:DESAC RS01365
gene id: 880072:DESAC_RS01365
uniprot id: F2NEH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

880072:DESAC RS13365
gene id: 880072:DESAC_RS13365
uniprot id: F2NIM6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

880072:DESAC RS01985
gene id: 880072:DESAC_RS01985
uniprot id: F2NEV0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

880072:DESAC RS07270
gene id: 880072:DESAC_RS07270
uniprot id: F2NJE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

880072:DESAC RS01755
gene id: 880072:DESAC_RS01755
uniprot id: F2NER0
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS08910
gene id: 880072:DESAC_RS08910
uniprot id: F2NI01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Vesicle
messages: gas vesicle

880072:DESAC RS07675
gene id: 880072:DESAC_RS07675
uniprot id: F2NHR0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

880072:DESAC RS05310
gene id: 880072:DESAC_RS05310
uniprot id: F2NH94
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Belongs to the complex I 51 kDa subunit family.

880072:DESAC RS05975
gene id: 880072:DESAC_RS05975
uniprot id: F2NHE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880072:DESAC RS09200
gene id: 880072:DESAC_RS09200
uniprot id: F2NJM8
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS03700
gene id: 880072:DESAC_RS03700
uniprot id: F2NF71
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

880072:DESAC RS08705
gene id: 880072:DESAC_RS08705
uniprot id: F2ND14
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

880072:DESAC RS14520
gene id: 880072:DESAC_RS14520
uniprot id: F2NE77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

880072:DESAC RS10675
gene id: 880072:DESAC_RS10675
uniprot id: F2NDB0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS07365
gene id: 880072:DESAC_RS07365
uniprot id: F2NCP9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

880072:DESAC RS07200
gene id: 880072:DESAC_RS07200
uniprot id: F2NJC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

880072:DESAC RS16425
gene id: 880072:DESAC_RS16425
uniprot id: F2NF80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

880072:DESAC RS11710
gene id: 880072:DESAC_RS11710
uniprot id: F2NFQ5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

880072:DESAC RS14655
gene id: 880072:DESAC_RS14655
uniprot id: F2NEA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

880072:DESAC RS05545
gene id: 880072:DESAC_RS05545
uniprot id: F2NCB6
names: Similarity
messages: Belongs to the FeoA family.

880072:DESAC RS11870
gene id: 880072:DESAC_RS11870
uniprot id: F2NFT6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880072:DESAC RS10530
gene id: 880072:DESAC_RS10530
uniprot id: F2NK02
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS09575
gene id: 880072:DESAC_RS09575
uniprot id: F2ND32
names: Similarity
messages: Belongs to the glutamate synthase family.

880072:DESAC RS01600
gene id: 880072:DESAC_RS01600
uniprot id: F2NEM8
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS00800
gene id: 880072:DESAC_RS00800
uniprot id: F2NBY1
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS00325
gene id: 880072:DESAC_RS00325
uniprot id: F2NJ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

880072:DESAC RS08095
gene id: 880072:DESAC_RS08095
uniprot id: F2NJG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

880072:DESAC RS02180
gene id: 880072:DESAC_RS02180
uniprot id: F2NEY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS00500
gene id: 880072:DESAC_RS00500
uniprot id: F2NJ39
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

880072:DESAC RS02820
gene id: 880072:DESAC_RS02820
uniprot id: F2NG43
names: Similarity
messages: Belongs to the pyruvate kinase family.

880072:DESAC RS05995
gene id: 880072:DESAC_RS05995
uniprot id: F2NHF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880072:DESAC RS01405
gene id: 880072:DESAC_RS01405
uniprot id: F2NEI6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

880072:DESAC RS14550
gene id: 880072:DESAC_RS14550
uniprot id: F2NE83
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

880072:DESAC RS12950
gene id: 880072:DESAC_RS12950
uniprot id: F2NDS1
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

880072:DESAC RS14470
gene id: 880072:DESAC_RS14470
uniprot id: F2NE67
names: Similarity
messages: Belongs to the HypD family.

880072:DESAC RS10620
gene id: 880072:DESAC_RS10620
uniprot id: F2ND99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

880072:DESAC RS13160
gene id: 880072:DESAC_RS13160
uniprot id: F2NDW3
names: Similarity
messages: Belongs to the DprA/Smf family.

880072:DESAC RS01440
gene id: 880072:DESAC_RS01440
uniprot id: F2NEJ4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

880072:DESAC RS07110
gene id: 880072:DESAC_RS07110
uniprot id: F2NJB1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

880072:DESAC RS12485
gene id: 880072:DESAC_RS12485
uniprot id: F2NIC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

880072:DESAC RS09300
gene id: 880072:DESAC_RS09300
uniprot id: F2NJP8
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

880072:DESAC RS07210
gene id: 880072:DESAC_RS07210
uniprot id: F2NJD1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

880072:DESAC RS01565
gene id: 880072:DESAC_RS01565
uniprot id: F2NEM1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880072:DESAC RS13110
gene id: 880072:DESAC_RS13110
uniprot id: F2NDV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

880072:DESAC RS05980
gene id: 880072:DESAC_RS05980
uniprot id: F2NHE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

880072:DESAC RS10495
gene id: 880072:DESAC_RS10495
uniprot id: F2NJZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

880072:DESAC RS13525
gene id: 880072:DESAC_RS13525
uniprot id: F2NIQ7
names: Similarity
messages: Belongs to the Skp family.

880072:DESAC RS00420
gene id: 880072:DESAC_RS00420
uniprot id: F2NGN7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

880072:DESAC RS01050
gene id: 880072:DESAC_RS01050
uniprot id: F2NEB8
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

880072:DESAC RS11905
gene id: 880072:DESAC_RS11905
uniprot id: F2NFU3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

880072:DESAC RS10880
gene id: 880072:DESAC_RS10880
uniprot id: F2NDF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

880072:DESAC RS14285
gene id: 880072:DESAC_RS14285
uniprot id: F2NIW9
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS03675
gene id: 880072:DESAC_RS03675
uniprot id: F2NF66
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

880072:DESAC RS02610
gene id: 880072:DESAC_RS02610
uniprot id: F2NFZ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS12530
gene id: 880072:DESAC_RS12530
uniprot id: F2NID3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

880072:DESAC RS03375
gene id: 880072:DESAC_RS03375
uniprot id: F2NGF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

880072:DESAC RS07115
gene id: 880072:DESAC_RS07115
uniprot id: F2NJB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

880072:DESAC RS03400
gene id: 880072:DESAC_RS03400
uniprot id: F2NGF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

880072:DESAC RS08385
gene id: 880072:DESAC_RS08385
uniprot id: F2NJL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

880072:DESAC RS02965
gene id: 880072:DESAC_RS02965
uniprot id: F2NG71
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS02995
gene id: 880072:DESAC_RS02995
uniprot id: F2NG77
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS12400
gene id: 880072:DESAC_RS12400
uniprot id: F2NDN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

880072:DESAC RS03225
gene id: 880072:DESAC_RS03225
uniprot id: F2NGB9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

880072:DESAC RS12375
gene id: 880072:DESAC_RS12375
uniprot id: F2NDN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

880072:DESAC RS04315
gene id: 880072:DESAC_RS04315
uniprot id: F2NGX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS13685
gene id: 880072:DESAC_RS13685
uniprot id: F2NDZ5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

880072:DESAC RS12010
gene id: 880072:DESAC_RS12010
uniprot id: F2NFW5
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS08805
gene id: 880072:DESAC_RS08805
uniprot id: F2NHY0
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS06445
gene id: 880072:DESAC_RS06445
uniprot id: F2NCL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

880072:DESAC RS07810
gene id: 880072:DESAC_RS07810
uniprot id: F2NHT8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

880072:DESAC RS10450
gene id: 880072:DESAC_RS10450
uniprot id: F2NJY6
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

880072:DESAC RS05510
gene id: 880072:DESAC_RS05510
uniprot id: F2NCA9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

880072:DESAC RS11475
gene id: 880072:DESAC_RS11475
uniprot id: F2NFL0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

880072:DESAC RS01880
gene id: 880072:DESAC_RS01880
uniprot id: F2NET1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

880072:DESAC RS07245
gene id: 880072:DESAC_RS07245
uniprot id: F2NJD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

880072:DESAC RS07370
gene id: 880072:DESAC_RS07370
uniprot id: F2NCQ0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

880072:DESAC RS09270
gene id: 880072:DESAC_RS09270
uniprot id: F2NJP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

880072:DESAC RS00625
gene id: 880072:DESAC_RS00625
uniprot id: F2NJ64
names: Similarity
messages: Belongs to the PucC family.

880072:DESAC RS13320
gene id: 880072:DESAC_RS13320
uniprot id: F2NIL7
names: Similarity
messages: Belongs to the TrpC family.

880072:DESAC RS08740
gene id: 880072:DESAC_RS08740
uniprot id: F2ND20
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

880072:DESAC RS10300
gene id: 880072:DESAC_RS10300
uniprot id: F2NJV6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

880072:DESAC RS10650
gene id: 880072:DESAC_RS10650
uniprot id: F2NDA5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

880072:DESAC RS02305
gene id: 880072:DESAC_RS02305
uniprot id: F2NF09
names: Similarity
messages: Belongs to the creatininase superfamily.

880072:DESAC RS08635
gene id: 880072:DESAC_RS08635
uniprot id: F2ND01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

880072:DESAC RS06225
gene id: 880072:DESAC_RS06225
uniprot id: F2NCH8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

880072:DESAC RS09565
gene id: 880072:DESAC_RS09565
uniprot id: F2ND30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

880072:DESAC RS09710
gene id: 880072:DESAC_RS09710
uniprot id: F2ND55
names: Similarity
messages: Belongs to the bacterial secretin family.

880072:DESAC RS07490
gene id: 880072:DESAC_RS07490
uniprot id: F2NCS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

880072:DESAC RS02005
gene id: 880072:DESAC_RS02005
uniprot id: F2NEV4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

880072:DESAC RS11610
gene id: 880072:DESAC_RS11610
uniprot id: F2NFN6
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

880072:DESAC RS07310
gene id: 880072:DESAC_RS07310
uniprot id: F2NCP2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

880072:DESAC RS05930
gene id: 880072:DESAC_RS05930
uniprot id: F2NHE0
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

880072:DESAC RS09365
gene id: 880072:DESAC_RS09365
uniprot id: F2NJR0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

880072:DESAC RS05235
gene id: 880072:DESAC_RS05235
uniprot id: F2NH79
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

880072:DESAC RS04965
gene id: 880072:DESAC_RS04965
uniprot id: F2NC75
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

880072:DESAC RS07230
gene id: 880072:DESAC_RS07230
uniprot id: F2NJD5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

880072:DESAC RS07155
gene id: 880072:DESAC_RS07155
uniprot id: F2NJC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

880072:DESAC RS01535
gene id: 880072:DESAC_RS01535
uniprot id: F2NEL5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

880072:DESAC RS07290
gene id: 880072:DESAC_RS07290
uniprot id: F2NJE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

880072:DESAC RS03500
gene id: 880072:DESAC_RS03500
uniprot id: F2NGH3
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS06835
gene id: 880072:DESAC_RS06835
uniprot id: F2NHP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

880072:DESAC RS01495
gene id: 880072:DESAC_RS01495
uniprot id: F2NEK6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

880072:DESAC RS11650
gene id: 880072:DESAC_RS11650
uniprot id: F2NFP3
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS08375
gene id: 880072:DESAC_RS08375
uniprot id: F2NJL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

880072:DESAC RS10505
gene id: 880072:DESAC_RS10505
uniprot id: F2NJZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880072:DESAC RS10605
gene id: 880072:DESAC_RS10605
uniprot id: F2ND96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

880072:DESAC RS12100
gene id: 880072:DESAC_RS12100
uniprot id: F2NDH6
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS03405
gene id: 880072:DESAC_RS03405
uniprot id: F2NGF6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

880072:DESAC RS00585
gene id: 880072:DESAC_RS00585
uniprot id: F2NJ55
names: Similarity
messages: Belongs to the alkaline phosphatase family.

880072:DESAC RS11550
gene id: 880072:DESAC_RS11550
uniprot id: F2NFM4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

880072:DESAC RS00090
gene id: 880072:DESAC_RS00090
uniprot id: F2NGL0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

880072:DESAC RS10610
gene id: 880072:DESAC_RS10610
uniprot id: F2ND97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

880072:DESAC RS16120
gene id: 880072:DESAC_RS16120
uniprot id: F2NDS7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

880072:DESAC RS06975
gene id: 880072:DESAC_RS06975
uniprot id: F2NJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

880072:DESAC RS15240
gene id: 880072:DESAC_RS15240
uniprot id: F2NHX4
names: Similarity
messages: Belongs to the methyltransferase superfamily. PrmA family.

880072:DESAC RS02200
gene id: 880072:DESAC_RS02200
uniprot id: F2NEY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS13340
gene id: 880072:DESAC_RS13340
uniprot id: F2NIM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

880072:DESAC RS11540
gene id: 880072:DESAC_RS11540
uniprot id: F2NFM2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

880072:DESAC RS05705
gene id: 880072:DESAC_RS05705
uniprot id: F2NCE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved Asp active site.

880072:DESAC RS03485
gene id: 880072:DESAC_RS03485
uniprot id: F2NGH0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

880072:DESAC RS11385
gene id: 880072:DESAC_RS11385
uniprot id: F2NFJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

880072:DESAC RS06005
gene id: 880072:DESAC_RS06005
uniprot id: F2NHF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

880072:DESAC RS03435
gene id: 880072:DESAC_RS03435
uniprot id: F2NGG1
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS07185
gene id: 880072:DESAC_RS07185
uniprot id: F2NJC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

880072:DESAC RS13545
gene id: 880072:DESAC_RS13545
uniprot id: F2NIR1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

880072:DESAC RS02365
gene id: 880072:DESAC_RS02365
uniprot id: F2NF21
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

880072:DESAC RS00815
gene id: 880072:DESAC_RS00815
uniprot id: F2NBY4
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

880072:DESAC RS08475
gene id: 880072:DESAC_RS08475
uniprot id: F2NCX2
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

880072:DESAC RS13780
gene id: 880072:DESAC_RS13780
uniprot id: F2NE14
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

880072:DESAC RS13155
gene id: 880072:DESAC_RS13155
uniprot id: F2NDW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

880072:DESAC RS13540
gene id: 880072:DESAC_RS13540
uniprot id: F2NIR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

880072:DESAC RS06330
gene id: 880072:DESAC_RS06330
uniprot id: F2NCJ8
names: Similarity
messages: Belongs to the transketolase family.

880072:DESAC RS11495
gene id: 880072:DESAC_RS11495
uniprot id: F2NFL4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

880072:DESAC RS03975
gene id: 880072:DESAC_RS03975
uniprot id: F2NGQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS10745
gene id: 880072:DESAC_RS10745
uniprot id: F2NDC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

880072:DESAC RS08465
gene id: 880072:DESAC_RS08465
uniprot id: F2NCX1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

880072:DESAC RS12640
gene id: 880072:DESAC_RS12640
uniprot id: F2NIF6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

880072:DESAC RS10440
gene id: 880072:DESAC_RS10440
uniprot id: F2NJY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

880072:DESAC RS14525
gene id: 880072:DESAC_RS14525
uniprot id: F2NE78
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

880072:DESAC RS14415
gene id: 880072:DESAC_RS14415
uniprot id: F2NE58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

880072:DESAC RS13315
gene id: 880072:DESAC_RS13315
uniprot id: F2NIL6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS01320
gene id: 880072:DESAC_RS01320
uniprot id: F2NEH0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

880072:DESAC RS05885
gene id: 880072:DESAC_RS05885
uniprot id: F2NHD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

880072:DESAC RS08075
gene id: 880072:DESAC_RS08075
uniprot id: F2NJG1
names: Similarity
messages: Belongs to the peptidase M16 family.

880072:DESAC RS03710
gene id: 880072:DESAC_RS03710
uniprot id: F2NF73
names: Similarity
messages: Belongs to the UPF0102 family.

880072:DESAC RS11400
gene id: 880072:DESAC_RS11400
uniprot id: F2NFJ6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

880072:DESAC RS13150
gene id: 880072:DESAC_RS13150
uniprot id: F2NDW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

880072:DESAC RS01015
gene id: 880072:DESAC_RS01015
uniprot id: F2NEB1
names: Similarity
messages: Belongs to the AdoMet synthase family.

880072:DESAC RS05275
gene id: 880072:DESAC_RS05275
uniprot id: F2NH87
names: Subcellular Location Annotation
messages: Cytoplasm

880072:DESAC RS12600
gene id: 880072:DESAC_RS12600
uniprot id: F2NIE8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

880072:DESAC RS01270
gene id: 880072:DESAC_RS01270
uniprot id: F2NEG1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

880072:DESAC RS00230
gene id: 880072:DESAC_RS00230
uniprot id: F2NGN7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

880072:DESAC RS14330
gene id: 880072:DESAC_RS14330
uniprot id: F2NE41
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

880072:DESAC RS00025
gene id: 880072:DESAC_RS00025
uniprot id: F2NGJ7
names: Similarity
messages: Belongs to the P(II) protein family.

880072:DESAC RS07900
gene id: 880072:DESAC_RS07900
uniprot id: F2NHV6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS07125
gene id: 880072:DESAC_RS07125
uniprot id: F2NJB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

880072:DESAC RS10020
gene id: 880072:DESAC_RS10020
uniprot id: F2NI73
names: Caution
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

880072:DESAC RS09985
gene id: 880072:DESAC_RS09985
uniprot id: F2NI66
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

880072:DESAC RS12740
gene id: 880072:DESAC_RS12740
uniprot id: F2NIH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

880072:DESAC RS09905
gene id: 880072:DESAC_RS09905
uniprot id: F2ND94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS04205
gene id: 880072:DESAC_RS04205
uniprot id: F2NGV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880072:DESAC RS12320
gene id: 880072:DESAC_RS12320
uniprot id: F2NDL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

880072:DESAC RS12260
gene id: 880072:DESAC_RS12260
uniprot id: F2NDK7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

880072:DESAC RS02435
gene id: 880072:DESAC_RS02435
uniprot id: F2NF35
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880072:DESAC RS09615
gene id: 880072:DESAC_RS09615
uniprot id: F2ND39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MS5 protein family.
messages: Nucleus

880072:DESAC RS07225
gene id: 880072:DESAC_RS07225
uniprot id: F2NJD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

880072:DESAC RS13000
gene id: 880072:DESAC_RS13000
uniprot id: F2NDT2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880072:DESAC RS10365
gene id: 880072:DESAC_RS10365
uniprot id: F2NJW9
names: Similarity
messages: Belongs to the GSP E family.

880072:DESAC RS15275
gene id: 880072:DESAC_RS15275
uniprot id: F2NI16
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

880072:DESAC RS03765
gene id: 880072:DESAC_RS03765
uniprot id: F2NF84
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

880072:DESAC RS11330
gene id: 880072:DESAC_RS11330
uniprot id: F2NFI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

880072:DESAC RS09195
gene id: 880072:DESAC_RS09195
uniprot id: F2NJM7
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS16115
gene id: 880072:DESAC_RS16115
uniprot id: F2NDS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

880072:DESAC RS04960
gene id: 880072:DESAC_RS04960
uniprot id: F2NC74
names: Similarity
messages: Belongs to the peptidase A31 family.

880072:DESAC RS13095
gene id: 880072:DESAC_RS13095
uniprot id: F2NDV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

880072:DESAC RS12115
gene id: 880072:DESAC_RS12115
uniprot id: F2NDH8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880072:DESAC RS09935
gene id: 880072:DESAC_RS09935
uniprot id: F2NI55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

880072:DESAC RS12435
gene id: 880072:DESAC_RS12435
uniprot id: F2NDP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

880072:DESAC RS00550
gene id: 880072:DESAC_RS00550
uniprot id: F2NJ48
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS14115
gene id: 880072:DESAC_RS14115
uniprot id: F2NIU1
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

880072:DESAC RS01540
gene id: 880072:DESAC_RS01540
uniprot id: F2NEL6
names: Subcellular Location Annotation
messages: Membrane

880072:DESAC RS00040
gene id: 880072:DESAC_RS00040
uniprot id: F2NGK0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.