876142:Eint 111780
gene id: 876142:Eint_111780
uniprot id: E0SA55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

876142:Eint 101230
gene id: 876142:Eint_101230
uniprot id: E0S9R3
names: Similarity
messages: Belongs to the PPP phosphatase family.

876142:Eint 040840
gene id: 876142:Eint_040840
uniprot id: E0S6N9
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

876142:Eint 100190
gene id: 876142:Eint_100190
uniprot id: E0S9G2
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

876142:Eint 061010
gene id: 876142:Eint_061010
uniprot id: E0S7M9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

876142:Eint 080270
gene id: 876142:Eint_080270
uniprot id: E0S8G9
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

876142:Eint 100670
gene id: 876142:Eint_100670
uniprot id: E0S9K8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

876142:Eint 021170
gene id: 876142:Eint_021170
uniprot id: E0S5X9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.

876142:Eint 030140
gene id: 876142:Eint_030140
uniprot id: E0S625
names: Similarity
messages: Belongs to the CHS7 family.

876142:Eint 100270
gene id: 876142:Eint_100270
uniprot id: E0S9G9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

876142:Eint 030820
gene id: 876142:Eint_030820
uniprot id: E0S691
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

876142:Eint 110740
gene id: 876142:Eint_110740
uniprot id: E0SAE9
names: Similarity
messages: Belongs to the cytidylyltransferase family.

876142:Eint 110110
gene id: 876142:Eint_110110
uniprot id: E0SA88
names: Similarity
messages: Belongs to the exportin family.

876142:Eint 101190
gene id: 876142:Eint_101190
uniprot id: E0S9Q9
names: Subcellular Location Annotation
messages: Cytoplasm

876142:Eint 030200
gene id: 876142:Eint_030200
uniprot id: E0S631
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

876142:Eint 090650
gene id: 876142:Eint_090650
uniprot id: E0S9D0
names: Similarity
messages: Belongs to the DeSI family.

876142:Eint 080850
gene id: 876142:Eint_080850
uniprot id: E0S8M5
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

876142:Eint 090530
gene id: 876142:Eint_090530
uniprot id: E0S9B8
names: Similarity
messages: Belongs to the NOC2 family.

876142:Eint 081190
gene id: 876142:Eint_081190
uniprot id: E0S8T4
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

876142:Eint 090810
gene id: 876142:Eint_090810
uniprot id: E0S9E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

876142:Eint 070400
gene id: 876142:Eint_070400
uniprot id: E0S7W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

876142:Eint 061380
gene id: 876142:Eint_061380
uniprot id: E0S7R4
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 111850
gene id: 876142:Eint_111850
uniprot id: E0SA62
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

876142:Eint 111400
gene id: 876142:Eint_111400
uniprot id: E0SA17
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 070310
gene id: 876142:Eint_070310
uniprot id: E0S7W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Membrane

876142:Eint 040740
gene id: 876142:Eint_040740
uniprot id: E0S6M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

876142:Eint 051400
gene id: 876142:Eint_051400
uniprot id: E0S701
names: Similarity
messages: Belongs to the peptidase T1A family.

876142:Eint 021260
gene id: 876142:Eint_021260
uniprot id: E0S5Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

876142:Eint 021330
gene id: 876142:Eint_021330
uniprot id: E0S5Z5
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

876142:Eint 011310
gene id: 876142:Eint_011310
uniprot id: E0S5K8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

876142:Eint 080020
gene id: 876142:Eint_080020
uniprot id: E0S8E5
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 071280
gene id: 876142:Eint_071280
uniprot id: E0S856
names: Similarity
messages: Belongs to the RMD1/sif2 family.

876142:Eint 111120
gene id: 876142:Eint_111120
uniprot id: E0S9Z0
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 081870
gene id: 876142:Eint_081870
uniprot id: E0S8B2
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

876142:Eint 090390
gene id: 876142:Eint_090390
uniprot id: E0S9A5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

876142:Eint 020830
gene id: 876142:Eint_020830
uniprot id: E0S5U6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

876142:Eint 050750
gene id: 876142:Eint_050750
uniprot id: E0S795
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

876142:Eint 011390
gene id: 876142:Eint_011390
uniprot id: E0S5L6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

876142:Eint 050670
gene id: 876142:Eint_050670
uniprot id: E0S787
names: Function
names: Similarity
messages: Belongs to the GPI family.
messages: In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.

876142:Eint 110920
gene id: 876142:Eint_110920
uniprot id: E0S9X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

876142:Eint 110060
gene id: 876142:Eint_110060
uniprot id: E0SA83
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 051110
gene id: 876142:Eint_051110
uniprot id: E0S6X2
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

876142:Eint 050030
gene id: 876142:Eint_050030
uniprot id: E0S724
names: Similarity
messages: Belongs to the UPF0329 family.

876142:Eint 081340
gene id: 876142:Eint_081340
uniprot id: E0S8C8
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 090940
gene id: 876142:Eint_090940
uniprot id: E0S8V7
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 021200
gene id: 876142:Eint_021200
uniprot id: E0S5Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus

876142:Eint 060075
gene id: 876142:Eint_060075
uniprot id: W8PKG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

876142:Eint 092020
gene id: 876142:Eint_092020
uniprot id: E0S993
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

876142:Eint 041190
gene id: 876142:Eint_041190
uniprot id: E0S6S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

876142:Eint 110770
gene id: 876142:Eint_110770
uniprot id: E0SAF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

876142:Eint 021460
gene id: 876142:Eint_021460
uniprot id: E0S607
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

876142:Eint 111500
gene id: 876142:Eint_111500
uniprot id: E0SA27
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

876142:Eint 010220
gene id: 876142:Eint_010220
uniprot id: E0S5A1
names: Similarity
messages: Belongs to the BRX1 family.

876142:Eint 090450
gene id: 876142:Eint_090450
uniprot id: E0S9B0
names: Similarity
messages: Belongs to the histone H4 family.

876142:Eint 051290
gene id: 876142:Eint_051290
uniprot id: E0S6Z0
names: Function
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

876142:Eint 050890
gene id: 876142:Eint_050890
uniprot id: E0S7A9
names: Similarity
messages: Belongs to the HAM1 NTPase family.

876142:Eint 061340
gene id: 876142:Eint_061340
uniprot id: E0S7R0
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

876142:Eint 060570
gene id: 876142:Eint_060570
uniprot id: E0S7I6
names: Similarity
messages: Belongs to the adenylate kinase family.

876142:Eint 071390
gene id: 876142:Eint_071390
uniprot id: E0S867
names: Similarity
messages: Belongs to the dopey family.

876142:Eint 030890
gene id: 876142:Eint_030890
uniprot id: E0S698
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

876142:Eint 101730
gene id: 876142:Eint_101730
uniprot id: E0S9W3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

876142:Eint 090130
gene id: 876142:Eint_090130
uniprot id: E0S950
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus

876142:Eint 110720
gene id: 876142:Eint_110720
uniprot id: E0SAE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

876142:Eint 091150
gene id: 876142:Eint_091150
uniprot id: E0S8X8
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 070295
gene id: 876142:Eint_070295
uniprot id: W8P910
names: Similarity
messages: Belongs to the UPF0235 family.

876142:Eint 091650
gene id: 876142:Eint_091650
uniprot id: E0S937
names: Similarity
messages: Belongs to the DEAD box helicase family.

876142:Eint 091310
gene id: 876142:Eint_091310
uniprot id: E0S8Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

876142:Eint 050880
gene id: 876142:Eint_050880
uniprot id: E0S7A8
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

876142:Eint 080950
gene id: 876142:Eint_080950
uniprot id: E0S8P4
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 080970
gene id: 876142:Eint_080970
uniprot id: E0S8P6
names: Similarity
messages: Belongs to the PHF5 family.

876142:Eint 030440
gene id: 876142:Eint_030440
uniprot id: E0S653
names: Similarity
messages: Belongs to the synaptobrevin family.

876142:Eint 080330
gene id: 876142:Eint_080330
uniprot id: E0S8H5
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 020655
gene id: 876142:Eint_020655
uniprot id: W8P8W5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

876142:Eint 021390
gene id: 876142:Eint_021390
uniprot id: E0S601
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

876142:Eint 050050
gene id: 876142:Eint_050050
uniprot id: E0S726
names: Similarity
messages: Belongs to the NTE family.

876142:Eint 010910
gene id: 876142:Eint_010910
uniprot id: E0S5G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

876142:Eint 030790
gene id: 876142:Eint_030790
uniprot id: E0S688
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

876142:Eint 030250
gene id: 876142:Eint_030250
uniprot id: E0S635
names: Similarity
messages: Belongs to the phosphohexose mutase family.

876142:Eint 051460
gene id: 876142:Eint_051460
uniprot id: E0S707
names: Similarity
messages: Belongs to the peptidase T1A family.

876142:Eint 091830
gene id: 876142:Eint_091830
uniprot id: E0S967
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Chromosome
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Nucleus

876142:Eint 101380
gene id: 876142:Eint_101380
uniprot id: E0S9S8
names: Similarity
messages: Belongs to the acetyltransferase family. GCN5 subfamily.

876142:Eint 081540
gene id: 876142:Eint_081540
uniprot id: E0S8N0
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

876142:Eint 050470
gene id: 876142:Eint_050470
uniprot id: E0S768
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

876142:Eint 031230
gene id: 876142:Eint_031230
uniprot id: E0S6D0
names: Similarity
messages: Belongs to the AAA ATPase family.

876142:Eint 040640
gene id: 876142:Eint_040640
uniprot id: E0S6L9
names: Similarity
messages: Belongs to the PPP phosphatase family.

876142:Eint 070500
gene id: 876142:Eint_070500
uniprot id: E0S7X9
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 100330
gene id: 876142:Eint_100330
uniprot id: E0S9H5
names: Similarity
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.

876142:Eint 020850
gene id: 876142:Eint_020850
uniprot id: E0S5U8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

876142:Eint 070120
gene id: 876142:Eint_070120
uniprot id: E0S7U2
names: Similarity
messages: Belongs to the AAA ATPase family.

876142:Eint 041570
gene id: 876142:Eint_041570
uniprot id: E0S6V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: Nucleus

876142:Eint 071090
gene id: 876142:Eint_071090
uniprot id: E0S837
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

876142:Eint 080820
gene id: 876142:Eint_080820
uniprot id: E0S8M2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

876142:Eint 051520
gene id: 876142:Eint_051520
uniprot id: E0S713
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 101070
gene id: 876142:Eint_101070
uniprot id: E0S9P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

876142:Eint 100750
gene id: 876142:Eint_100750
uniprot id: E0S9L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.
messages: nucleolus

876142:Eint 101080
gene id: 876142:Eint_101080
uniprot id: E0S9P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

876142:Eint 051430
gene id: 876142:Eint_051430
uniprot id: E0S704
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

876142:Eint 090050
gene id: 876142:Eint_090050
uniprot id: E0S918
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Membrane

876142:Eint 110700
gene id: 876142:Eint_110700
uniprot id: E0SAE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus

876142:Eint 071750
gene id: 876142:Eint_071750
uniprot id: E0S899
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

876142:Eint 010060
gene id: 876142:Eint_010060
uniprot id: E0S585
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

876142:Eint 070730
gene id: 876142:Eint_070730
uniprot id: E0S802
names: Similarity
messages: Belongs to the SEC3 family.

876142:Eint 090120
gene id: 876142:Eint_090120
uniprot id: E0S949
names: Similarity
messages: Belongs to the SecY/SEC61-alpha family.

876142:Eint 061450
gene id: 876142:Eint_061450
uniprot id: E0S7S1
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 101690
gene id: 876142:Eint_101690
uniprot id: E0S9V9
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

876142:Eint 030520
gene id: 876142:Eint_030520
uniprot id: E0S661
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 020210
gene id: 876142:Eint_020210
uniprot id: E0S5N7
names: Similarity
messages: Belongs to the activator 1 small subunits family.

876142:Eint 101250
gene id: 876142:Eint_101250
uniprot id: E0S9R5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

876142:Eint 070020
gene id: 876142:Eint_070020
uniprot id: E0S7T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

876142:Eint 071340
gene id: 876142:Eint_071340
uniprot id: E0S862
names: Function
names: Similarity
messages: Component of the 60S subunit of the ribosome.
messages: In the N-terminal section; belongs to the ubiquitin family.

876142:Eint 110180
gene id: 876142:Eint_110180
uniprot id: E0SA95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

876142:Eint 070060
gene id: 876142:Eint_070060
uniprot id: E0S7T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

876142:Eint 060920
gene id: 876142:Eint_060920
uniprot id: E0S7M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Cytoplasm
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

876142:Eint 021320
gene id: 876142:Eint_021320
uniprot id: E0S5Z4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

876142:Eint 021050
gene id: 876142:Eint_021050
uniprot id: E0S5W7
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 060820
gene id: 876142:Eint_060820
uniprot id: E0S7L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

876142:Eint 041270
gene id: 876142:Eint_041270
uniprot id: E0S6T1
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

876142:Eint 101430
gene id: 876142:Eint_101430
uniprot id: E0S9T3
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 070760
gene id: 876142:Eint_070760
uniprot id: E0S805
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

876142:Eint 101540
gene id: 876142:Eint_101540
uniprot id: E0S9U4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

876142:Eint 090240
gene id: 876142:Eint_090240
uniprot id: E0S972
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

876142:Eint 090090
gene id: 876142:Eint_090090
uniprot id: E0S922
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

876142:Eint 010370
gene id: 876142:Eint_010370
uniprot id: E0S5B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

876142:Eint 030610
gene id: 876142:Eint_030610
uniprot id: E0S670
names: Similarity
messages: Belongs to the RNR ribonuclease family.

876142:Eint 111150
gene id: 876142:Eint_111150
uniprot id: E0S9Z2
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

876142:Eint 010300
gene id: 876142:Eint_010300
uniprot id: E0S5A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

876142:Eint 070880
gene id: 876142:Eint_070880
uniprot id: E0S816
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

876142:Eint 111630
gene id: 876142:Eint_111630
uniprot id: E0SA40
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

876142:Eint 040510
gene id: 876142:Eint_040510
uniprot id: E0S6K6
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 071310
gene id: 876142:Eint_071310
uniprot id: E0S859
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.

876142:Eint 070740
gene id: 876142:Eint_070740
uniprot id: E0S803
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

876142:Eint 070040
gene id: 876142:Eint_070040
uniprot id: E0S7T4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

876142:Eint 010380
gene id: 876142:Eint_010380
uniprot id: E0S5B6
names: Similarity
messages: Belongs to the NifU family.

876142:Eint 080620
gene id: 876142:Eint_080620
uniprot id: E0S8K2
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

876142:Eint 101760
gene id: 876142:Eint_101760
uniprot id: E0S9W6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

876142:Eint 061350
gene id: 876142:Eint_061350
uniprot id: E0S7R1
names: Similarity
messages: Belongs to the NEMF family.

876142:Eint 030110
gene id: 876142:Eint_030110
uniprot id: E0S622
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

876142:Eint 070710
gene id: 876142:Eint_070710
uniprot id: E0S800
names: Subcellular Location Annotation
messages: Nucleus membrane
messages: perinuclear region

876142:Eint 090930
gene id: 876142:Eint_090930
uniprot id: E0S8V6
names: Similarity
messages: Belongs to the SPCS3 family.

876142:Eint 060180
gene id: 876142:Eint_060180
uniprot id: E0S7E8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

876142:Eint 011300
gene id: 876142:Eint_011300
uniprot id: E0S5K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

876142:Eint 071730
gene id: 876142:Eint_071730
uniprot id: E0S897
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

876142:Eint 031350
gene id: 876142:Eint_031350
uniprot id: E0S6E2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

876142:Eint 091350
gene id: 876142:Eint_091350
uniprot id: E0S8Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Nucleus

876142:Eint 010550
gene id: 876142:Eint_010550
uniprot id: E0S5D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

876142:Eint 110830
gene id: 876142:Eint_110830
uniprot id: E0SAF8
names: Similarity
messages: Belongs to the protein kinase superfamily.

876142:Eint 020180
gene id: 876142:Eint_020180
uniprot id: E0S5N4
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 070690
gene id: 876142:Eint_070690
uniprot id: E0S7Z8
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 020380
gene id: 876142:Eint_020380
uniprot id: E0S5Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

876142:Eint 091400
gene id: 876142:Eint_091400
uniprot id: E0S903
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

876142:Eint 041110
gene id: 876142:Eint_041110
uniprot id: E0S6R5
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

876142:Eint 051560
gene id: 876142:Eint_051560
uniprot id: E0S717
names: Subcellular Location Annotation
messages: nucleolus

876142:Eint 091420
gene id: 876142:Eint_091420
uniprot id: E0S905
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP11 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

876142:Eint 060110
gene id: 876142:Eint_060110
uniprot id: E0S7E1
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

876142:Eint 101480
gene id: 876142:Eint_101480
uniprot id: E0S9T8
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 051100
gene id: 876142:Eint_051100
uniprot id: E0S6X1
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 091250
gene id: 876142:Eint_091250
uniprot id: E0S8Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

876142:Eint 050620
gene id: 876142:Eint_050620
uniprot id: E0S782
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

876142:Eint 070930
gene id: 876142:Eint_070930
uniprot id: E0S821
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.

876142:Eint 101370
gene id: 876142:Eint_101370
uniprot id: E0S9S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

876142:Eint 041370
gene id: 876142:Eint_041370
uniprot id: E0S6U1
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

876142:Eint 021060
gene id: 876142:Eint_021060
uniprot id: E0S5W8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

876142:Eint 081380
gene id: 876142:Eint_081380
uniprot id: E0S8D3
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 030620
gene id: 876142:Eint_030620
uniprot id: E0S671
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

876142:Eint 021100
gene id: 876142:Eint_021100
uniprot id: E0S5X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

876142:Eint 100060
gene id: 876142:Eint_100060
uniprot id: E0S9F1
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

876142:Eint 101290
gene id: 876142:Eint_101290
uniprot id: E0S9R9
names: Subcellular Location Annotation
messages: Cytoplasm

876142:Eint 071360
gene id: 876142:Eint_071360
uniprot id: E0S864
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

876142:Eint 050960
gene id: 876142:Eint_050960
uniprot id: E0S7B5
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

876142:Eint 060020
gene id: 876142:Eint_060020
uniprot id: E0S7D2
names: Similarity
messages: Belongs to the transketolase family.

876142:Eint 030400
gene id: 876142:Eint_030400
uniprot id: E0S649
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

876142:Eint 101160
gene id: 876142:Eint_101160
uniprot id: E0S9Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

876142:Eint 100960
gene id: 876142:Eint_100960
uniprot id: E0S9N7
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 080570
gene id: 876142:Eint_080570
uniprot id: E0S8J8
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

876142:Eint 011170
gene id: 876142:Eint_011170
uniprot id: E0S5J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

876142:Eint 040470
gene id: 876142:Eint_040470
uniprot id: E0S6K2
names: Similarity
messages: Belongs to the HSF family.

876142:Eint 011060
gene id: 876142:Eint_011060
uniprot id: E0S5I3
names: Similarity
messages: Belongs to the peptidase S8 family.

876142:Eint 071615
gene id: 876142:Eint_071615
uniprot id: W8P9B6
names: Similarity
messages: Belongs to the FYV7 family.

876142:Eint 080210
gene id: 876142:Eint_080210
uniprot id: E0S8G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

876142:Eint 041450
gene id: 876142:Eint_041450
uniprot id: E0S6U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

876142:Eint 081300
gene id: 876142:Eint_081300
uniprot id: E0S8U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Membrane

876142:Eint 040530
gene id: 876142:Eint_040530
uniprot id: E0S6K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

876142:Eint 080180
gene id: 876142:Eint_080180
uniprot id: E0S8G0
names: Similarity
messages: Belongs to the cyclin family.

876142:Eint 081040
gene id: 876142:Eint_081040
uniprot id: E0S8Q3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

876142:Eint 111440
gene id: 876142:Eint_111440
uniprot id: E0SA21
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

876142:Eint 021290
gene id: 876142:Eint_021290
uniprot id: E0S5Z1
names: Similarity
messages: Belongs to the V-ATPase G subunit family.

876142:Eint 030040
gene id: 876142:Eint_030040
uniprot id: E0S615
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
messages: Membrane

876142:Eint 050060
gene id: 876142:Eint_050060
uniprot id: E0S727
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

876142:Eint 071240
gene id: 876142:Eint_071240
uniprot id: E0S852
names: Function
messages: Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).

876142:Eint 101400
gene id: 876142:Eint_101400
uniprot id: E0S9T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

876142:Eint 041220
gene id: 876142:Eint_041220
uniprot id: E0S6S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

876142:Eint 080810
gene id: 876142:Eint_080810
uniprot id: E0S8M1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

876142:Eint 020450
gene id: 876142:Eint_020450
uniprot id: E0S5R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

876142:Eint 061370
gene id: 876142:Eint_061370
uniprot id: E0S7R3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Component of the GINS complex.
messages: Nucleus

876142:Eint 111240
gene id: 876142:Eint_111240
uniprot id: E0SA01
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

876142:Eint 051340
gene id: 876142:Eint_051340
uniprot id: E0S6Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

876142:Eint 060400
gene id: 876142:Eint_060400
uniprot id: E0S7G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

876142:Eint 101530
gene id: 876142:Eint_101530
uniprot id: E0S9U3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

876142:Eint 051280
gene id: 876142:Eint_051280
uniprot id: E0S6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

876142:Eint 071290
gene id: 876142:Eint_071290
uniprot id: E0S857
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

876142:Eint 051380
gene id: 876142:Eint_051380
uniprot id: E0S6Z9
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

876142:Eint 111760
gene id: 876142:Eint_111760
uniprot id: E0SA53
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 040200
gene id: 876142:Eint_040200
uniprot id: E0S6H6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

876142:Eint 011140
gene id: 876142:Eint_011140
uniprot id: E0S5J1
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

876142:Eint 071600
gene id: 876142:Eint_071600
uniprot id: E0S884
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

876142:Eint 111930
gene id: 876142:Eint_111930
uniprot id: E0SA70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STE12 transcription factor family.
messages: Nucleus

876142:Eint 031400
gene id: 876142:Eint_031400
uniprot id: E0S6E7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

876142:Eint 111280
gene id: 876142:Eint_111280
uniprot id: E0SA05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

876142:Eint 100450
gene id: 876142:Eint_100450
uniprot id: E0S9I6
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

876142:Eint 021180
gene id: 876142:Eint_021180
uniprot id: E0S5Y0
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

876142:Eint 010820
gene id: 876142:Eint_010820
uniprot id: E0S5F9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

876142:Eint 051170
gene id: 876142:Eint_051170
uniprot id: E0S6X8
names: Similarity
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.

876142:Eint 110380
gene id: 876142:Eint_110380
uniprot id: E0SAB3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

876142:Eint 111660
gene id: 876142:Eint_111660
uniprot id: E0SA43
names: Similarity
messages: Belongs to the importin alpha family.

876142:Eint 051590
gene id: 876142:Eint_051590
uniprot id: E0S720
names: Similarity
messages: Belongs to the activator 1 large subunit family.

876142:Eint 081890
gene id: 876142:Eint_081890
uniprot id: E0S8B3
names: Similarity
messages: Belongs to the protein kinase superfamily.

876142:Eint 011220
gene id: 876142:Eint_011220
uniprot id: E0S5J9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

876142:Eint 031140
gene id: 876142:Eint_031140
uniprot id: E0S6C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

876142:Eint 040540
gene id: 876142:Eint_040540
uniprot id: E0S6K9
names: Similarity
messages: Belongs to the peptidase M24B family.

876142:Eint 041590
gene id: 876142:Eint_041590
uniprot id: E0S6W1
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 071270
gene id: 876142:Eint_071270
uniprot id: E0S855
names: Similarity
messages: Belongs to the FAM72 family.

876142:Eint 050250
gene id: 876142:Eint_050250
uniprot id: E0S746
names: Similarity
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

876142:Eint 050320
gene id: 876142:Eint_050320
uniprot id: E0S753
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

876142:Eint 030840
gene id: 876142:Eint_030840
uniprot id: E0S693
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

876142:Eint 030560
gene id: 876142:Eint_030560
uniprot id: E0S665
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

876142:Eint 030940
gene id: 876142:Eint_030940
uniprot id: E0S6A3
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 091550
gene id: 876142:Eint_091550
uniprot id: E0S927
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Membrane

876142:Eint 110680
gene id: 876142:Eint_110680
uniprot id: E0SAE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

876142:Eint 091750
gene id: 876142:Eint_091750
uniprot id: E0S947
names: Similarity
messages: Belongs to the CDC73 family.

876142:Eint 020750
gene id: 876142:Eint_020750
uniprot id: E0S5T9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

876142:Eint 020530
gene id: 876142:Eint_020530
uniprot id: E0S5R7
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

876142:Eint 020700
gene id: 876142:Eint_020700
uniprot id: E0S5T4
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

876142:Eint 020010
gene id: 876142:Eint_020010
uniprot id: E0S5L7
names: Similarity
messages: Belongs to the UPF0328 family.

876142:Eint 070680
gene id: 876142:Eint_070680
uniprot id: E0S7Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane
messages: Water channel required to facilitate the transport of water across membranes. Involved in osmotolerance.

876142:Eint 021140
gene id: 876142:Eint_021140
uniprot id: E0S5X6
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 041050
gene id: 876142:Eint_041050
uniprot id: E0S6Q9
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

876142:Eint 051010
gene id: 876142:Eint_051010
uniprot id: E0S7C0
names: Similarity
messages: Belongs to the NARF family.

876142:Eint 091600
gene id: 876142:Eint_091600
uniprot id: E0S932
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

876142:Eint 041000
gene id: 876142:Eint_041000
uniprot id: E0S6Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

876142:Eint 020370
gene id: 876142:Eint_020370
uniprot id: E0S5Q3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

876142:Eint 020020
gene id: 876142:Eint_020020
uniprot id: E0S5L8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

876142:Eint 040780
gene id: 876142:Eint_040780
uniprot id: E0S6N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

876142:Eint 030360
gene id: 876142:Eint_030360
uniprot id: E0S645
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

876142:Eint 021120
gene id: 876142:Eint_021120
uniprot id: E0S5X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

876142:Eint 050690
gene id: 876142:Eint_050690
uniprot id: E0S789
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

876142:Eint 061240
gene id: 876142:Eint_061240
uniprot id: E0S7Q1
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 050270
gene id: 876142:Eint_050270
uniprot id: E0S748
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

876142:Eint 040940
gene id: 876142:Eint_040940
uniprot id: E0S6P8
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 111270
gene id: 876142:Eint_111270
uniprot id: E0SA04
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

876142:Eint 101150
gene id: 876142:Eint_101150
uniprot id: E0S9Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

876142:Eint 110960
gene id: 876142:Eint_110960
uniprot id: E0S9X4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

876142:Eint 071150
gene id: 876142:Eint_071150
uniprot id: E0S843
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

876142:Eint 011360
gene id: 876142:Eint_011360
uniprot id: E0S585
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

876142:Eint 040450
gene id: 876142:Eint_040450
uniprot id: E0S6K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.
messages: nucleolus

876142:Eint 081100
gene id: 876142:Eint_081100
uniprot id: E0S8S5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

876142:Eint 011040
gene id: 876142:Eint_011040
uniprot id: E0S5I1
names: Similarity
messages: Belongs to the cytochrome b5 family.

876142:Eint 111030
gene id: 876142:Eint_111030
uniprot id: E0S9Y1
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 090220
gene id: 876142:Eint_090220
uniprot id: E0S959
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

876142:Eint 081960
gene id: 876142:Eint_081960
uniprot id: E0S8C0
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

876142:Eint 030120
gene id: 876142:Eint_030120
uniprot id: E0S623
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

876142:Eint 020560
gene id: 876142:Eint_020560
uniprot id: E0S5S0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

876142:Eint 091440
gene id: 876142:Eint_091440
uniprot id: E0S907
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

876142:Eint 111220
gene id: 876142:Eint_111220
uniprot id: E0S9Z9
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 101260
gene id: 876142:Eint_101260
uniprot id: E0S9R6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

876142:Eint 100210
gene id: 876142:Eint_100210
uniprot id: E0S9G4
names: Similarity
messages: Belongs to the RNase PH family.

876142:Eint 081930
gene id: 876142:Eint_081930
uniprot id: E0S8B7
names: Similarity
messages: Belongs to the AAA ATPase family.

876142:Eint 090380
gene id: 876142:Eint_090380
uniprot id: E0S9A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

876142:Eint 050240
gene id: 876142:Eint_050240
uniprot id: E0S745
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

876142:Eint 091140
gene id: 876142:Eint_091140
uniprot id: E0S8X7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

876142:Eint 071410
gene id: 876142:Eint_071410
uniprot id: E0S869
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.

876142:Eint 050780
gene id: 876142:Eint_050780
uniprot id: E0S798
names: Similarity
messages: Belongs to the peptidase C48 family.

876142:Eint 101300
gene id: 876142:Eint_101300
uniprot id: E0S9S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Nucleus

876142:Eint 070660
gene id: 876142:Eint_070660
uniprot id: E0S7Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

876142:Eint 111050
gene id: 876142:Eint_111050
uniprot id: E0S9Y3
names: Subcellular Location Annotation
messages: nucleolus

876142:Eint 010110
gene id: 876142:Eint_010110
uniprot id: E0S590
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

876142:Eint 021020
gene id: 876142:Eint_021020
uniprot id: E0S5W4
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.

876142:Eint 061520
gene id: 876142:Eint_061520
uniprot id: E0S7S8
names: Similarity
messages: Belongs to the WD repeat rae1 family.

876142:Eint 020730
gene id: 876142:Eint_020730
uniprot id: E0S5T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus

876142:Eint 040270
gene id: 876142:Eint_040270
uniprot id: E0S6I3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

876142:Eint 101570
gene id: 876142:Eint_101570
uniprot id: E0S9U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

876142:Eint 060230
gene id: 876142:Eint_060230
uniprot id: E0S7F3
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

876142:Eint 100610
gene id: 876142:Eint_100610
uniprot id: E0S9K2
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

876142:Eint 031250
gene id: 876142:Eint_031250
uniprot id: E0S6D2
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

876142:Eint 051370
gene id: 876142:Eint_051370
uniprot id: E0S6Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
messages: Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.
messages: Cytoplasm
messages: P-body

876142:Eint 061600
gene id: 876142:Eint_061600
uniprot id: E0S7C9
names: Similarity
messages: Belongs to the UPF0329 family.

876142:Eint 110300
gene id: 876142:Eint_110300
uniprot id: E0SAA5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

876142:Eint 060410
gene id: 876142:Eint_060410
uniprot id: E0S7H0
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

876142:Eint 090300
gene id: 876142:Eint_090300
uniprot id: E0S978
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

876142:Eint 100550
gene id: 876142:Eint_100550
uniprot id: E0S9J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

876142:Eint 080650
gene id: 876142:Eint_080650
uniprot id: E0S8K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

876142:Eint 071130
gene id: 876142:Eint_071130
uniprot id: E0S841
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

876142:Eint 060350
gene id: 876142:Eint_060350
uniprot id: E0S7G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

876142:Eint 060420
gene id: 876142:Eint_060420
uniprot id: E0S7H1
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 090730
gene id: 876142:Eint_090730
uniprot id: E0S9D8
names: Similarity
messages: Belongs to the DNA polymerase delta/II small subunit family.

876142:Eint 060360
gene id: 876142:Eint_060360
uniprot id: E0S7G5
names: Similarity
messages: Belongs to the RNase Z family.

876142:Eint 050940
gene id: 876142:Eint_050940
uniprot id: E0S7B3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

876142:Eint 040290
gene id: 876142:Eint_040290
uniprot id: E0S6I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

876142:Eint 030310
gene id: 876142:Eint_030310
uniprot id: E0S640
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 081290
gene id: 876142:Eint_081290
uniprot id: E0S8U4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

876142:Eint 071720
gene id: 876142:Eint_071720
uniprot id: E0S896
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

876142:Eint 100890
gene id: 876142:Eint_100890
uniprot id: E0S9N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

876142:Eint 110355
gene id: 876142:Eint_110355
uniprot id: W8PKL4
names: Similarity
messages: Belongs to the BolA/IbaG family.

876142:Eint 101680
gene id: 876142:Eint_101680
uniprot id: E0S9V8
names: Similarity
messages: Belongs to the HIT family.

876142:Eint 091530
gene id: 876142:Eint_091530
uniprot id: E0S925
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

876142:Eint 040610
gene id: 876142:Eint_040610
uniprot id: E0S6L6
names: Similarity
messages: Belongs to the polyprenol kinase family.

876142:Eint 090670
gene id: 876142:Eint_090670
uniprot id: E0S9D2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

876142:Eint 020360
gene id: 876142:Eint_020360
uniprot id: E0S5Q2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

876142:Eint 070460
gene id: 876142:Eint_070460
uniprot id: E0S7X5
names: Similarity
messages: Belongs to the protein kinase superfamily.

876142:Eint 040110
gene id: 876142:Eint_040110
uniprot id: E0S6G8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane
messages: May function both as a monomer and a homodimer.

876142:Eint 041380
gene id: 876142:Eint_041380
uniprot id: E0S6U2
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 050530
gene id: 876142:Eint_050530
uniprot id: E0S774
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

876142:Eint 110980
gene id: 876142:Eint_110980
uniprot id: E0S9X6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

876142:Eint 010480
gene id: 876142:Eint_010480
uniprot id: E0S5C6
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

876142:Eint 031320
gene id: 876142:Eint_031320
uniprot id: E0S6D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

876142:Eint 110640
gene id: 876142:Eint_110640
uniprot id: E0SAD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

876142:Eint 080590
gene id: 876142:Eint_080590
uniprot id: E0S8K0
names: Similarity
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.

876142:Eint 091700
gene id: 876142:Eint_091700
uniprot id: E0S942
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUF2 family.
messages: kinetochore

876142:Eint 111830
gene id: 876142:Eint_111830
uniprot id: E0SA60
names: Function
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.

876142:Eint 091320
gene id: 876142:Eint_091320
uniprot id: E0S8Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

876142:Eint 090900
gene id: 876142:Eint_090900
uniprot id: E0S8V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.

876142:Eint 010770
gene id: 876142:Eint_010770
uniprot id: E0S5F4
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

876142:Eint 010320
gene id: 876142:Eint_010320
uniprot id: E0S5B0
names: Similarity
messages: Belongs to the XPC family.

876142:Eint 030710
gene id: 876142:Eint_030710
uniprot id: E0S680
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

876142:Eint 081770
gene id: 876142:Eint_081770
uniprot id: E0S8A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus

876142:Eint 111110
gene id: 876142:Eint_111110
uniprot id: E0S9Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

876142:Eint 110660
gene id: 876142:Eint_110660
uniprot id: E0SAE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

876142:Eint 070970
gene id: 876142:Eint_070970
uniprot id: E0S825
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

876142:Eint 101650
gene id: 876142:Eint_101650
uniprot id: E0S9V5
names: Similarity
messages: Belongs to the enolase family.

876142:Eint 030500
gene id: 876142:Eint_030500
uniprot id: E0S659
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

876142:Eint 081800
gene id: 876142:Eint_081800
uniprot id: E0S8A6
names: Function
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.

876142:Eint 051330
gene id: 876142:Eint_051330
uniprot id: E0S6Z4
names: Similarity
messages: Belongs to the DEAD box helicase family.

876142:Eint 010630
gene id: 876142:Eint_010630
uniprot id: E0S5E1
names: Similarity
messages: Belongs to the thymidine kinase family.

876142:Eint 060270
gene id: 876142:Eint_060270
uniprot id: E0S7F7
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 090010
gene id: 876142:Eint_090010
uniprot id: E0S8Z7
names: Similarity
messages: Belongs to the UPF0329 family.

876142:Eint 100640
gene id: 876142:Eint_100640
uniprot id: E0S9K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: nucleolus

876142:Eint 110435
gene id: 876142:Eint_110435
uniprot id: W8P961
names: Similarity
messages: Belongs to the EAF6 family.

876142:Eint 080800
gene id: 876142:Eint_080800
uniprot id: E0S8M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

876142:Eint 100770
gene id: 876142:Eint_100770
uniprot id: E0S9L8
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

876142:Eint 040990
gene id: 876142:Eint_040990
uniprot id: E0S6Q3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

876142:Eint 100980
gene id: 876142:Eint_100980
uniprot id: E0S9N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

876142:Eint 080260
gene id: 876142:Eint_080260
uniprot id: E0S8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

876142:Eint 100930
gene id: 876142:Eint_100930
uniprot id: E0S9N4
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

876142:Eint 041350
gene id: 876142:Eint_041350
uniprot id: E0S6T9
names: Similarity
messages: Belongs to the CutA family.

876142:Eint 100040
gene id: 876142:Eint_100040
uniprot id: E0S9E9
names: Similarity
messages: Belongs to the protein kinase superfamily.

876142:Eint 020930
gene id: 876142:Eint_020930
uniprot id: E0S5V6
names: Similarity
messages: Belongs to the archease family.

876142:Eint 040690
gene id: 876142:Eint_040690
uniprot id: E0S6M4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

876142:Eint 060380
gene id: 876142:Eint_060380
uniprot id: E0S7G7
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

876142:Eint 060450
gene id: 876142:Eint_060450
uniprot id: E0S7H4
names: Similarity
messages: Belongs to the TUB family.

876142:Eint 070780
gene id: 876142:Eint_070780
uniprot id: E0S807
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.

876142:Eint 100540
gene id: 876142:Eint_100540
uniprot id: E0S9J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: Nucleus

876142:Eint 020620
gene id: 876142:Eint_020620
uniprot id: E0S5S6
names: Similarity
messages: Belongs to the DEAD box helicase family.

876142:Eint 110840
gene id: 876142:Eint_110840
uniprot id: E0SAF9
names: Similarity
messages: Belongs to the DCP1 family.

876142:Eint 080540
gene id: 876142:Eint_080540
uniprot id: E0S8J5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

876142:Eint 020680
gene id: 876142:Eint_020680
uniprot id: E0S5T2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

876142:Eint 071670
gene id: 876142:Eint_071670
uniprot id: E0S891
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

876142:Eint 030380
gene id: 876142:Eint_030380
uniprot id: E0S647
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

876142:Eint 010530
gene id: 876142:Eint_010530
uniprot id: E0S5D1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.

876142:Eint 110410
gene id: 876142:Eint_110410
uniprot id: E0SAB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

876142:Eint 110970
gene id: 876142:Eint_110970
uniprot id: E0S9X5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERF4 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with ERF2.

876142:Eint 101240
gene id: 876142:Eint_101240
uniprot id: E0S9R4
names: Similarity
messages: Belongs to the MIP18 family.

876142:Eint 070260
gene id: 876142:Eint_070260
uniprot id: E0S7V5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

876142:Eint 061490
gene id: 876142:Eint_061490
uniprot id: E0S7S5
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

876142:Eint 010260
gene id: 876142:Eint_010260
uniprot id: E0S5A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Membrane
messages: Probably involved in transport through the plasma membrane.

876142:Eint 060640
gene id: 876142:Eint_060640
uniprot id: E0S7J3
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

876142:Eint 092060
gene id: 876142:Eint_092060
uniprot id: E0S997
names: Similarity
messages: Belongs to the UPF0328 family.

876142:Eint 090720
gene id: 876142:Eint_090720
uniprot id: E0S9D7
names: Function
messages: Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote termination of transcription by RNA polymerase II.

876142:Eint 110020
gene id: 876142:Eint_110020
uniprot id: E0SA77
names: Similarity
messages: Belongs to the UPF0328 family.

876142:Eint 050155
gene id: 876142:Eint_050155
uniprot id: W8PKG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPI1 family.
messages: Nucleus
messages: Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.

876142:Eint 081260
gene id: 876142:Eint_081260
uniprot id: E0S8U1
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 041200
gene id: 876142:Eint_041200
uniprot id: E0S6S4
names: Similarity
messages: Belongs to the thymidylate kinase family.

876142:Eint 101280
gene id: 876142:Eint_101280
uniprot id: E0S9R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

876142:Eint 020120
gene id: 876142:Eint_020120
uniprot id: E0S5M8
names: Similarity
messages: Belongs to the lipin family.

876142:Eint 050990
gene id: 876142:Eint_050990
uniprot id: E0S7B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

876142:Eint 100250
gene id: 876142:Eint_100250
uniprot id: E0S9G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

876142:Eint 091820
gene id: 876142:Eint_091820
uniprot id: E0S966
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

876142:Eint 010970
gene id: 876142:Eint_010970
uniprot id: E0S5H4
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

876142:Eint 041120
gene id: 876142:Eint_041120
uniprot id: E0S6R6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

876142:Eint 100090
gene id: 876142:Eint_100090
uniprot id: E0S9F3
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

876142:Eint 040850
gene id: 876142:Eint_040850
uniprot id: E0S6P0
names: Similarity
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Tetramer of two alpha and two beta subunits.

876142:Eint 080245
gene id: 876142:Eint_080245
uniprot id: W8P9C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

876142:Eint 080780
gene id: 876142:Eint_080780
uniprot id: E0S8L8
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

876142:Eint 100370
gene id: 876142:Eint_100370
uniprot id: E0S9H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Membrane

876142:Eint 101670
gene id: 876142:Eint_101670
uniprot id: E0S9V7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

876142:Eint 081630
gene id: 876142:Eint_081630
uniprot id: E0S8Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
messages: centromere

876142:Eint 031290
gene id: 876142:Eint_031290
uniprot id: E0S6D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Cytoplasm

876142:Eint 110780
gene id: 876142:Eint_110780
uniprot id: E0SAF3
names: Subcellular Location Annotation
messages: nucleolus

876142:Eint 091460
gene id: 876142:Eint_091460
uniprot id: E0S909
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

876142:Eint 111890
gene id: 876142:Eint_111890
uniprot id: E0SA66
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

876142:Eint 090590
gene id: 876142:Eint_090590
uniprot id: E0S9C4
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

876142:Eint 040570
gene id: 876142:Eint_040570
uniprot id: E0S6L2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

876142:Eint 070900
gene id: 876142:Eint_070900
uniprot id: E0S818
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

876142:Eint 041230
gene id: 876142:Eint_041230
uniprot id: E0S6S7
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

876142:Eint 100390
gene id: 876142:Eint_100390
uniprot id: E0S9I1
names: Similarity
messages: Belongs to the DEAD box helicase family.

876142:Eint 100620
gene id: 876142:Eint_100620
uniprot id: E0S9K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.

876142:Eint 030300
gene id: 876142:Eint_030300
uniprot id: E0S639
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

876142:Eint 041390
gene id: 876142:Eint_041390
uniprot id: E0S6U3
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

876142:Eint 100570
gene id: 876142:Eint_100570
uniprot id: E0S9J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

876142:Eint 050260
gene id: 876142:Eint_050260
uniprot id: E0S747
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

876142:Eint 091660
gene id: 876142:Eint_091660
uniprot id: E0S938
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

876142:Eint 100180
gene id: 876142:Eint_100180
uniprot id: E0S9G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Cytoplasm
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

876142:Eint 101560
gene id: 876142:Eint_101560
uniprot id: E0S9U6
names: Similarity
messages: Belongs to the cytidylyltransferase family.

876142:Eint 070430
gene id: 876142:Eint_070430
uniprot id: E0S7X2
names: Similarity
messages: Belongs to the MCM family.

876142:Eint 080720
gene id: 876142:Eint_080720
uniprot id: E0S8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

876142:Eint 100760
gene id: 876142:Eint_100760
uniprot id: E0S9L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

876142:Eint 021350
gene id: 876142:Eint_021350
uniprot id: E0S5Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

876142:Eint 031300
gene id: 876142:Eint_031300
uniprot id: E0S6D7
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 060250
gene id: 876142:Eint_060250
uniprot id: E0S7F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

876142:Eint 071610
gene id: 876142:Eint_071610
uniprot id: E0S885
names: Similarity
messages: Belongs to the AAA ATPase family.

876142:Eint 011100
gene id: 876142:Eint_011100
uniprot id: E0S5I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

876142:Eint 061500
gene id: 876142:Eint_061500
uniprot id: E0S7S6
names: Similarity
messages: Belongs to the NDK family.

876142:Eint 101610
gene id: 876142:Eint_101610
uniprot id: E0S9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

876142:Eint 070320
gene id: 876142:Eint_070320
uniprot id: E0S7W1
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

876142:Eint 100860
gene id: 876142:Eint_100860
uniprot id: E0S9M7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

876142:Eint 101360
gene id: 876142:Eint_101360
uniprot id: E0S9S6
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 030960
gene id: 876142:Eint_030960
uniprot id: E0S6A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

876142:Eint 050040
gene id: 876142:Eint_050040
uniprot id: E0S725
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

876142:Eint 020740
gene id: 876142:Eint_020740
uniprot id: E0S5T8
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

876142:Eint 070390
gene id: 876142:Eint_070390
uniprot id: E0S7W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

876142:Eint 060160
gene id: 876142:Eint_060160
uniprot id: E0S7E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

876142:Eint 111320
gene id: 876142:Eint_111320
uniprot id: E0SA09
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

876142:Eint 010860
gene id: 876142:Eint_010860
uniprot id: E0S5G3
names: Similarity
messages: Belongs to the MBF1 family.

876142:Eint 021250
gene id: 876142:Eint_021250
uniprot id: E0S5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm

876142:Eint 080170
gene id: 876142:Eint_080170
uniprot id: E0S8F9
names: Similarity
messages: Belongs to the V-ATPase H subunit family.

876142:Eint 100260
gene id: 876142:Eint_100260
uniprot id: E0S9G8
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

876142:Eint 031260
gene id: 876142:Eint_031260
uniprot id: E0S6D3
names: Similarity
messages: Belongs to the MYG1 family.

876142:Eint 011330
gene id: 876142:Eint_011330
uniprot id: E0S5L0
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 080200
gene id: 876142:Eint_080200
uniprot id: E0S8G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

876142:Eint 110670
gene id: 876142:Eint_110670
uniprot id: E0SAE2
names: Similarity
messages: Belongs to the MCM family.

876142:Eint 040050
gene id: 876142:Eint_040050
uniprot id: E0S6G3
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

876142:Eint 080360
gene id: 876142:Eint_080360
uniprot id: E0S8H8
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 111430
gene id: 876142:Eint_111430
uniprot id: E0SA20
names: Similarity
messages: Belongs to the hexokinase family.

876142:Eint 040070
gene id: 876142:Eint_040070
uniprot id: E0S6G5
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

876142:Eint 060100
gene id: 876142:Eint_060100
uniprot id: E0S7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

876142:Eint 031280
gene id: 876142:Eint_031280
uniprot id: E0S6D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm

876142:Eint 081080
gene id: 876142:Eint_081080
uniprot id: E0S8S3
names: Similarity
messages: Belongs to the DEAD box helicase family.

876142:Eint 100470
gene id: 876142:Eint_100470
uniprot id: E0S9I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

876142:Eint 051490
gene id: 876142:Eint_051490
uniprot id: E0S710
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

876142:Eint 070480
gene id: 876142:Eint_070480
uniprot id: E0S7X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

876142:Eint 041290
gene id: 876142:Eint_041290
uniprot id: E0S6T3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

876142:Eint 110170
gene id: 876142:Eint_110170
uniprot id: E0SA94
names: Similarity
messages: Belongs to the Rab GDI family.

876142:Eint 110440
gene id: 876142:Eint_110440
uniprot id: E0SAB9
names: Similarity
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

876142:Eint 030010
gene id: 876142:Eint_030010
uniprot id: E0S612
names: Similarity
messages: Belongs to the UPF0329 family.

876142:Eint 071370
gene id: 876142:Eint_071370
uniprot id: E0S865
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 100700
gene id: 876142:Eint_100700
uniprot id: Q6XMH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

876142:Eint 031520
gene id: 876142:Eint_031520
uniprot id: E0S6F9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YAF9 family.
messages: Component of the SWR1 chromatin-remodeling complex and of the NuA4 histone acetyltransferase complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for an H2A variant leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised.
messages: Cytoplasm
messages: Nucleus
messages: The coiled-coil domain is required for assembly into the NuA4 complex.

876142:Eint 010190
gene id: 876142:Eint_010190
uniprot id: E0S598
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: nucleolus

876142:Eint 070530
gene id: 876142:Eint_070530
uniprot id: E0S7Y2
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

876142:Eint 110760
gene id: 876142:Eint_110760
uniprot id: E0SAF1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

876142:Eint 050820
gene id: 876142:Eint_050820
uniprot id: E0S7A2
names: Subcellular Location Annotation
messages: nucleolus

876142:Eint 021430
gene id: 876142:Eint_021430
uniprot id: E0S605
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

876142:Eint 100780
gene id: 876142:Eint_100780
uniprot id: E0S9L9
names: Similarity
messages: Belongs to the MAK16 family.

876142:Eint 041040
gene id: 876142:Eint_041040
uniprot id: E0S6Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

876142:Eint 040770
gene id: 876142:Eint_040770
uniprot id: E0S6N2
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

876142:Eint 080150
gene id: 876142:Eint_080150
uniprot id: E0S8F7
names: Similarity
messages: Belongs to the protein kinase superfamily.

876142:Eint 050080
gene id: 876142:Eint_050080
uniprot id: E0S729
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

876142:Eint 060290
gene id: 876142:Eint_060290
uniprot id: E0S7F9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

876142:Eint 081430
gene id: 876142:Eint_081430
uniprot id: E0S8D8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

876142:Eint 030180
gene id: 876142:Eint_030180
uniprot id: E0S629
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

876142:Eint 081200
gene id: 876142:Eint_081200
uniprot id: E0S8T5
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

876142:Eint 070590
gene id: 876142:Eint_070590
uniprot id: E0S7Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

876142:Eint 060760
gene id: 876142:Eint_060760
uniprot id: E0S7K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSU72 phosphatase family.
messages: Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.
messages: Component of the cleavage and polyadenylation factor (CPF) complex.
messages: Nucleus
messages: Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).

876142:Eint 010330
gene id: 876142:Eint_010330
uniprot id: E0S5B1
names: Function
names: Similarity
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.

876142:Eint 101390
gene id: 876142:Eint_101390
uniprot id: E0S9S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

876142:Eint 111510
gene id: 876142:Eint_111510
uniprot id: E0SA28
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

876142:Eint 040970
gene id: 876142:Eint_040970
uniprot id: E0S6Q1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

876142:Eint 050710
gene id: 876142:Eint_050710
uniprot id: E0S791
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Membrane

876142:Eint 060860
gene id: 876142:Eint_060860
uniprot id: E0S7L4
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 070840
gene id: 876142:Eint_070840
uniprot id: E0S812
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

876142:Eint 100050
gene id: 876142:Eint_100050
uniprot id: E0S9F0
names: Similarity
messages: Belongs to the AAA ATPase family.

876142:Eint 081525
gene id: 876142:Eint_081525
uniprot id: W8Q202
names: Similarity
messages: Belongs to the NOP10 family.

876142:Eint 061040
gene id: 876142:Eint_061040
uniprot id: E0S7N2
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

876142:Eint 110620
gene id: 876142:Eint_110620
uniprot id: E0SAD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNO1 family.
messages: Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).
messages: Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.

876142:Eint 111060
gene id: 876142:Eint_111060
uniprot id: E0S9Y4
names: Similarity
messages: Belongs to the phospholipase D family.

876142:Eint 061540
gene id: 876142:Eint_061540
uniprot id: E0S7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

876142:Eint 041560
gene id: 876142:Eint_041560
uniprot id: E0S6V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fungal TPase family.
messages: First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus

876142:Eint 111160
gene id: 876142:Eint_111160
uniprot id: E0S9Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

876142:Eint 031000
gene id: 876142:Eint_031000
uniprot id: E0S6A8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

876142:Eint 011250
gene id: 876142:Eint_011250
uniprot id: E0S5K2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

876142:Eint 111410
gene id: 876142:Eint_111410
uniprot id: E0SA18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with TRM82.
messages: Nucleus

876142:Eint 100220
gene id: 876142:Eint_100220
uniprot id: E0S9G5
names: Subcellular Location Annotation
messages: nucleolus

876142:Eint 030810
gene id: 876142:Eint_030810
uniprot id: E0S690
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.

876142:Eint 110100
gene id: 876142:Eint_110100
uniprot id: E0SA87
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

876142:Eint 090080
gene id: 876142:Eint_090080
uniprot id: E0S921
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

876142:Eint 110480
gene id: 876142:Eint_110480
uniprot id: E0SAC3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

876142:Eint 030020
gene id: 876142:Eint_030020
uniprot id: E0S613
names: Similarity
messages: Belongs to the UPF0329 family.

876142:Eint 100840
gene id: 876142:Eint_100840
uniprot id: E0S9M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

876142:Eint 040250
gene id: 876142:Eint_040250
uniprot id: E0S6I1
names: Similarity
messages: Belongs to the proteasome subunit S2 family.

876142:Eint 070030
gene id: 876142:Eint_070030
uniprot id: E0S7T3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

876142:Eint 111170
gene id: 876142:Eint_111170
uniprot id: E0S9Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Endomembrane system
messages: Vacuole membrane

876142:Eint 030900
gene id: 876142:Eint_030900
uniprot id: E0S699
names: Similarity
messages: Belongs to the 14-3-3 family.

876142:Eint 020150
gene id: 876142:Eint_020150
uniprot id: E0S5N1
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

876142:Eint 111290
gene id: 876142:Eint_111290
uniprot id: E0SA06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

876142:Eint 091625
gene id: 876142:Eint_091625
uniprot id: W8P945
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

876142:Eint 080500
gene id: 876142:Eint_080500
uniprot id: E0S8J2
names: Similarity
messages: Belongs to the CWC16 family.

876142:Eint 040920
gene id: 876142:Eint_040920
uniprot id: E0S6P6
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 030340
gene id: 876142:Eint_030340
uniprot id: E0S643
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

876142:Eint 090950
gene id: 876142:Eint_090950
uniprot id: E0S8V8
names: Similarity
messages: Belongs to the PPP phosphatase family.

876142:Eint 030190
gene id: 876142:Eint_030190
uniprot id: E0S630
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.

876142:Eint 050370
gene id: 876142:Eint_050370
uniprot id: E0S758
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

876142:Eint 060790
gene id: 876142:Eint_060790
uniprot id: E0S7K8
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 100400
gene id: 876142:Eint_100400
uniprot id: E0S9I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

876142:Eint 030730
gene id: 876142:Eint_030730
uniprot id: E0S682
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

876142:Eint 010170
gene id: 876142:Eint_010170
uniprot id: E0S596
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

876142:Eint 030650
gene id: 876142:Eint_030650
uniprot id: E0S674
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NCBP2 family.
messages: Nucleus

876142:Eint 080830
gene id: 876142:Eint_080830
uniprot id: E0S8M3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.
messages: Mitochondrion
messages: Nucleus

876142:Eint 080130
gene id: 876142:Eint_080130
uniprot id: E0S8F6
names: Function
names: Similarity
messages: Belongs to the WD repeat SEC31 family.
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.

876142:Eint 061260
gene id: 876142:Eint_061260
uniprot id: E0S7Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

876142:Eint 111210
gene id: 876142:Eint_111210
uniprot id: E0S9Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum

876142:Eint 041130
gene id: 876142:Eint_041130
uniprot id: E0S6R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

876142:Eint 110090
gene id: 876142:Eint_110090
uniprot id: E0SA86
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 100900
gene id: 876142:Eint_100900
uniprot id: E0S9N1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

876142:Eint 090600
gene id: 876142:Eint_090600
uniprot id: E0S9C5
names: Similarity
messages: Belongs to the pyruvate kinase family.

876142:Eint 050300
gene id: 876142:Eint_050300
uniprot id: E0S751
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

876142:Eint 101550
gene id: 876142:Eint_101550
uniprot id: E0S9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

876142:Eint 040030
gene id: 876142:Eint_040030
uniprot id: E0S6G1
names: Similarity
messages: Belongs to the UPF0329 family.

876142:Eint 110030
gene id: 876142:Eint_110030
uniprot id: E0SA78
names: Function
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

876142:Eint 040800
gene id: 876142:Eint_040800
uniprot id: E0S6N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

876142:Eint 111360
gene id: 876142:Eint_111360
uniprot id: E0SA13
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 091610
gene id: 876142:Eint_091610
uniprot id: E0S933
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

876142:Eint 110790
gene id: 876142:Eint_110790
uniprot id: E0SAF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

876142:Eint 100790
gene id: 876142:Eint_100790
uniprot id: E0S9M0
names: Similarity
messages: Belongs to the Luc7 family.

876142:Eint 070800
gene id: 876142:Eint_070800
uniprot id: E0S809
names: Similarity
messages: Belongs to the cullin family.

876142:Eint 030950
gene id: 876142:Eint_030950
uniprot id: E0S6A4
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 030970
gene id: 876142:Eint_030970
uniprot id: E0S6A6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

876142:Eint 091110
gene id: 876142:Eint_091110
uniprot id: E0S8X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

876142:Eint 070110
gene id: 876142:Eint_070110
uniprot id: E0S7U1
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

876142:Eint 031460
gene id: 876142:Eint_031460
uniprot id: E0S6F3
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 110230
gene id: 876142:Eint_110230
uniprot id: E0SA99
names: Similarity
messages: Belongs to the SEC6 family.

876142:Eint 080840
gene id: 876142:Eint_080840
uniprot id: E0S8M4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

876142:Eint 110800
gene id: 876142:Eint_110800
uniprot id: E0SAF5
names: Similarity
messages: Belongs to the eIF-2-alpha family.

876142:Eint 100460
gene id: 876142:Eint_100460
uniprot id: E0S9I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Membrane

876142:Eint 080480
gene id: 876142:Eint_080480
uniprot id: E0S8J0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

876142:Eint 111920
gene id: 876142:Eint_111920
uniprot id: E0SA69
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

876142:Eint 081450
gene id: 876142:Eint_081450
uniprot id: E0S8E0
names: Similarity
messages: Belongs to the protein kinase superfamily.

876142:Eint 051310
gene id: 876142:Eint_051310
uniprot id: E0S6Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

876142:Eint 041432
gene id: 876142:Eint_041432
uniprot id: W8Q1U6
names: Similarity
messages: Belongs to the SKP1 family.

876142:Eint 101020
gene id: 876142:Eint_101020
uniprot id: E0S9P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

876142:Eint 110330
gene id: 876142:Eint_110330
uniprot id: E0SAA8
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

876142:Eint 040320
gene id: 876142:Eint_040320
uniprot id: E0S6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

876142:Eint 020720
gene id: 876142:Eint_020720
uniprot id: E0S5T6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

876142:Eint 030690
gene id: 876142:Eint_030690
uniprot id: E0S678
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.
messages: Cytoplasm

876142:Eint 081050
gene id: 876142:Eint_081050
uniprot id: E0S8Q4
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

876142:Eint 030280
gene id: 876142:Eint_030280
uniprot id: E0S637
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

876142:Eint 050570
gene id: 876142:Eint_050570
uniprot id: E0S778
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

876142:Eint 010030
gene id: 876142:Eint_010030
uniprot id: E0S582
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

876142:Eint 020420
gene id: 876142:Eint_020420
uniprot id: E0S5Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anamorsin family.
messages: Cytoplasm

876142:Eint 040730
gene id: 876142:Eint_040730
uniprot id: E0S6M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

876142:Eint 050380
gene id: 876142:Eint_050380
uniprot id: E0S759
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus

876142:Eint 070910
gene id: 876142:Eint_070910
uniprot id: E0S819
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Nucleus

876142:Eint 111900
gene id: 876142:Eint_111900
uniprot id: E0SA67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

876142:Eint 101030
gene id: 876142:Eint_101030
uniprot id: E0S9P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ING family.
messages: Nucleus

876142:Eint 110900
gene id: 876142:Eint_110900
uniprot id: E0S9W8
names: Similarity
messages: Belongs to the AAA ATPase family.

876142:Eint 051020
gene id: 876142:Eint_051020
uniprot id: E0S7C1
names: Similarity
messages: Belongs to the APC10 family.

876142:Eint 080320
gene id: 876142:Eint_080320
uniprot id: E0S8H4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

876142:Eint 071700
gene id: 876142:Eint_071700
uniprot id: E0S894
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 061410
gene id: 876142:Eint_061410
uniprot id: E0S7R7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

876142:Eint 050280
gene id: 876142:Eint_050280
uniprot id: E0S749
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

876142:Eint 101000
gene id: 876142:Eint_101000
uniprot id: E0S9P1
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

876142:Eint 031110
gene id: 876142:Eint_031110
uniprot id: E0S6B9
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

876142:Eint 111670
gene id: 876142:Eint_111670
uniprot id: E0SA44
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

876142:Eint 051070
gene id: 876142:Eint_051070
uniprot id: E0S6W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

876142:Eint 061190
gene id: 876142:Eint_061190
uniprot id: E0S7P7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

876142:Eint 111350
gene id: 876142:Eint_111350
uniprot id: E0SA12
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

876142:Eint 050220
gene id: 876142:Eint_050220
uniprot id: E0S743
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

876142:Eint 040950
gene id: 876142:Eint_040950
uniprot id: E0S6P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cytoplasm

876142:Eint 100480
gene id: 876142:Eint_100480
uniprot id: E0S9I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Membrane

876142:Eint 051620
gene id: 876142:Eint_051620
uniprot id: E0S723
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

876142:Eint 110070
gene id: 876142:Eint_110070
uniprot id: E0SA84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus

876142:Eint 061480
gene id: 876142:Eint_061480
uniprot id: E0S7S4
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

876142:Eint 050290
gene id: 876142:Eint_050290
uniprot id: E0S750
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

876142:Eint 110190
gene id: 876142:Eint_110190
uniprot id: E0SA96
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

876142:Eint 061460
gene id: 876142:Eint_061460
uniprot id: E0S7S2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
messages: Cytoplasm
messages: Nucleus

876142:Eint 021160
gene id: 876142:Eint_021160
uniprot id: E0S5X8
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 060310
gene id: 876142:Eint_060310
uniprot id: E0S7G1
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

876142:Eint 060090
gene id: 876142:Eint_060090
uniprot id: E0S7D9
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 100200
gene id: 876142:Eint_100200
uniprot id: E0S9G3
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

876142:Eint 071710
gene id: 876142:Eint_071710
uniprot id: E0S895
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 060540
gene id: 876142:Eint_060540
uniprot id: E0S7I3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

876142:Eint 081900
gene id: 876142:Eint_081900
uniprot id: E0S8B4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

876142:Eint 071300
gene id: 876142:Eint_071300
uniprot id: E0S858
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

876142:Eint 080220
gene id: 876142:Eint_080220
uniprot id: E0S8G4
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

876142:Eint 110530
gene id: 876142:Eint_110530
uniprot id: E0SAC8
names: Similarity
messages: Belongs to the PPP phosphatase family.

876142:Eint 091050
gene id: 876142:Eint_091050
uniprot id: E0S8W8
names: Function
names: Similarity
messages: Belongs to the peptidase C13 family.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

876142:Eint 080730
gene id: 876142:Eint_080730
uniprot id: E0S8L3
names: Similarity
messages: Belongs to the type-1 OGG1 family.

876142:Eint 110710
gene id: 876142:Eint_110710
uniprot id: E0SAE6
names: Similarity
messages: Belongs to the AAA ATPase family.

876142:Eint 110690
gene id: 876142:Eint_110690
uniprot id: E0SAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Required both for recombination and for the repair of DNA damage caused by X-rays.

876142:Eint 051140
gene id: 876142:Eint_051140
uniprot id: E0S6X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.

876142:Eint 070300
gene id: 876142:Eint_070300
uniprot id: E0S7V9
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

876142:Eint 091520
gene id: 876142:Eint_091520
uniprot id: E0S924
names: Similarity
messages: Belongs to the DEAD box helicase family.

876142:Eint 080390
gene id: 876142:Eint_080390
uniprot id: E0S8I1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

876142:Eint 090820
gene id: 876142:Eint_090820
uniprot id: E0S9E7
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

876142:Eint 100150
gene id: 876142:Eint_100150
uniprot id: E0S9F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

876142:Eint 081830
gene id: 876142:Eint_081830
uniprot id: E0S8A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

876142:Eint 051580
gene id: 876142:Eint_051580
uniprot id: E0S719
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

876142:Eint 041070
gene id: 876142:Eint_041070
uniprot id: E0S6R1
names: Similarity
messages: Belongs to the actin family.

876142:Eint 090500
gene id: 876142:Eint_090500
uniprot id: E0S9B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: nuclear pore complex

876142:Eint 111770
gene id: 876142:Eint_111770
uniprot id: E0SA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

876142:Eint 021110
gene id: 876142:Eint_021110
uniprot id: E0S5X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

876142:Eint 031130
gene id: 876142:Eint_031130
uniprot id: E0S6C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

876142:Eint 111980
gene id: 876142:Eint_111980
uniprot id: E0SA75
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

876142:Eint 101410
gene id: 876142:Eint_101410
uniprot id: E0S9T1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

876142:Eint 011270
gene id: 876142:Eint_011270
uniprot id: E0S5K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

876142:Eint 091170
gene id: 876142:Eint_091170
uniprot id: E0S8Y0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

876142:Eint 091360
gene id: 876142:Eint_091360
uniprot id: E0S8Z9
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

876142:Eint 061590
gene id: 876142:Eint_061590
uniprot id: E0S7C8
names: Similarity
messages: Belongs to the UPF0329 family.

876142:Eint 110750
gene id: 876142:Eint_110750
uniprot id: E0SAF0
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

876142:Eint 061430
gene id: 876142:Eint_061430
uniprot id: E0S7R9
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

876142:Eint 070640
gene id: 876142:Eint_070640
uniprot id: E0S7Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

876142:Eint 070550
gene id: 876142:Eint_070550
uniprot id: E0S7Y4
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

876142:Eint 110420
gene id: 876142:Eint_110420
uniprot id: E0SAB7
names: Similarity
messages: Belongs to the peptidase M67A family.

876142:Eint 100940
gene id: 876142:Eint_100940
uniprot id: E0S9N5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

876142:Eint 111710
gene id: 876142:Eint_111710
uniprot id: E0SA48
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

876142:Eint 010340
gene id: 876142:Eint_010340
uniprot id: E0S5B2
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 031070
gene id: 876142:Eint_031070
uniprot id: E0S6B5
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 011290
gene id: 876142:Eint_011290
uniprot id: E0S5K6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

876142:Eint 100820
gene id: 876142:Eint_100820
uniprot id: E0S9M3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

876142:Eint 041010
gene id: 876142:Eint_041010
uniprot id: E0S6Q5
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 110630
gene id: 876142:Eint_110630
uniprot id: E0SAD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

876142:Eint 081250
gene id: 876142:Eint_081250
uniprot id: E0S8U0
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

876142:Eint 100580
gene id: 876142:Eint_100580
uniprot id: E0S9J9
names: Similarity
messages: Belongs to the dynein heavy chain family.

876142:Eint 091380
gene id: 876142:Eint_091380
uniprot id: E0S901
names: Similarity
messages: Belongs to the activator 1 small subunits family.

876142:Eint 030060
gene id: 876142:Eint_030060
uniprot id: E0S617
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 031270
gene id: 876142:Eint_031270
uniprot id: E0S6D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

876142:Eint 051230
gene id: 876142:Eint_051230
uniprot id: E0S6Y4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

876142:Eint 060430
gene id: 876142:Eint_060430
uniprot id: E0S7H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

876142:Eint 101130
gene id: 876142:Eint_101130
uniprot id: E0S9Q3
names: Similarity
messages: Belongs to the UFD1 family.

876142:Eint 020880
gene id: 876142:Eint_020880
uniprot id: E0S5V1
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 071540
gene id: 876142:Eint_071540
uniprot id: E0S878
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

876142:Eint 100350
gene id: 876142:Eint_100350
uniprot id: E0S9H7
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

876142:Eint 110320
gene id: 876142:Eint_110320
uniprot id: E0SAA7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

876142:Eint 010350
gene id: 876142:Eint_010350
uniprot id: E0S5B3
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

876142:Eint 030580
gene id: 876142:Eint_030580
uniprot id: E0S667
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

876142:Eint 100110
gene id: 876142:Eint_100110
uniprot id: E0S9F5
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

876142:Eint 020890
gene id: 876142:Eint_020890
uniprot id: E0S5V2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

876142:Eint 030410
gene id: 876142:Eint_030410
uniprot id: E0S650
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

876142:Eint 110050
gene id: 876142:Eint_110050
uniprot id: E0SA80
names: Similarity
messages: Belongs to the protein kinase superfamily.

876142:Eint 101420
gene id: 876142:Eint_101420
uniprot id: E0S9T2
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 071760
gene id: 876142:Eint_071760
uniprot id: E0S8A0
names: Similarity
messages: Belongs to the MYG1 family.

876142:Eint 101740
gene id: 876142:Eint_101740
uniprot id: E0S9W4
names: Similarity
messages: Belongs to the peptidase M17 family.

876142:Eint 111560
gene id: 876142:Eint_111560
uniprot id: E0SA33
names: Similarity
messages: Belongs to the peptidase T1A family.

876142:Eint 040975
gene id: 876142:Eint_040975
uniprot id: W8PGN4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

876142:Eint 021340
gene id: 876142:Eint_021340
uniprot id: E0S5Z6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

876142:Eint 080760
gene id: 876142:Eint_080760
uniprot id: E0S8L6
names: Subcellular Location Annotation
messages: Cytoplasm

876142:Eint 090630
gene id: 876142:Eint_090630
uniprot id: E0S9C8
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 1 subfamily.

876142:Eint 020870
gene id: 876142:Eint_020870
uniprot id: E0S5V0
names: Similarity
messages: Belongs to the MAD1 family.

876142:Eint 081750
gene id: 876142:Eint_081750
uniprot id: E0S8R9
names: Similarity
messages: Belongs to the protein kinase superfamily.

876142:Eint 050230
gene id: 876142:Eint_050230
uniprot id: E0S744
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

876142:Eint 061320
gene id: 876142:Eint_061320
uniprot id: E0S7Q8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

876142:Eint 051060
gene id: 876142:Eint_051060
uniprot id: E0S6W7
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

876142:Eint 110240
gene id: 876142:Eint_110240
uniprot id: E0SAA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

876142:Eint 100710
gene id: 876142:Eint_100710
uniprot id: E0S9L2
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 071230
gene id: 876142:Eint_071230
uniprot id: E0S851
names: Similarity
messages: Belongs to the protein kinase superfamily.

876142:Eint 091880
gene id: 876142:Eint_091880
uniprot id: E0S980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

876142:Eint 091690
gene id: 876142:Eint_091690
uniprot id: E0S941
names: Subcellular Location Annotation
messages: Cytoplasm

876142:Eint 090885
gene id: 876142:Eint_090885
uniprot id: W8PKK1
names: Similarity
messages: Belongs to the YOS1 family.

876142:Eint 091940
gene id: 876142:Eint_091940
uniprot id: E0S985
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

876142:Eint 050590
gene id: 876142:Eint_050590
uniprot id: E0S780
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

876142:Eint 090320
gene id: 876142:Eint_090320
uniprot id: E0S998
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus

876142:Eint 101640
gene id: 876142:Eint_101640
uniprot id: E0S9V4
names: Similarity
messages: Belongs to the DEAD box helicase family.

876142:Eint 050390
gene id: 876142:Eint_050390
uniprot id: E0S760
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

876142:Eint 061170
gene id: 876142:Eint_061170
uniprot id: E0S7P5
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

876142:Eint 060690
gene id: 876142:Eint_060690
uniprot id: E0S7J8
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

876142:Eint 030170
gene id: 876142:Eint_030170
uniprot id: E0S628
names: Function
names: Similarity
messages: Belongs to the UDPGP type 1 family.
messages: Plays a central role as a glucosyl donor in cellular metabolic pathways.

876142:Eint 011240
gene id: 876142:Eint_011240
uniprot id: E0S5K1
names: Similarity
messages: Belongs to the frataxin family.

876142:Eint 041160
gene id: 876142:Eint_041160
uniprot id: E0S6S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

876142:Eint 081420
gene id: 876142:Eint_081420
uniprot id: E0S8D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

876142:Eint 070850
gene id: 876142:Eint_070850
uniprot id: E0S813
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

876142:Eint 111820
gene id: 876142:Eint_111820
uniprot id: E0SA59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

876142:Eint 040560
gene id: 876142:Eint_040560
uniprot id: E0S6L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

876142:Eint 091470
gene id: 876142:Eint_091470
uniprot id: E0S910
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

876142:Eint 020260
gene id: 876142:Eint_020260
uniprot id: E0S5P2
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 041090
gene id: 876142:Eint_041090
uniprot id: E0S6R3
names: Similarity
messages: Belongs to the TOP6A family.

876142:Eint 040580
gene id: 876142:Eint_040580
uniprot id: E0S6L3
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

876142:Eint 050140
gene id: 876142:Eint_050140
uniprot id: E0S735
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

876142:Eint 060630
gene id: 876142:Eint_060630
uniprot id: E0S7J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

876142:Eint 071630
gene id: 876142:Eint_071630
uniprot id: E0S887
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

876142:Eint 060170
gene id: 876142:Eint_060170
uniprot id: E0S7E7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

876142:Eint 040900
gene id: 876142:Eint_040900
uniprot id: E0S6P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Nucleus

876142:Eint 081920
gene id: 876142:Eint_081920
uniprot id: E0S8B6
names: Similarity
messages: Belongs to the protein kinase superfamily.

876142:Eint 100500
gene id: 876142:Eint_100500
uniprot id: E0S9J1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

876142:Eint 091910
gene id: 876142:Eint_091910
uniprot id: E0S982
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Cytoplasm

876142:Eint 040590
gene id: 876142:Eint_040590
uniprot id: E0S6L4
names: Similarity
messages: Belongs to the SWI5/SAE3 family.

876142:Eint 082000
gene id: 876142:Eint_082000
uniprot id: E0S8C4
names: Similarity
messages: Belongs to the UPF0328 family.

876142:Eint 060870
gene id: 876142:Eint_060870
uniprot id: E0S7L5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

876142:Eint 091010
gene id: 876142:Eint_091010
uniprot id: E0S8W4
names: Similarity
messages: Belongs to the cyclin family.

876142:Eint 030430
gene id: 876142:Eint_030430
uniprot id: E0S652
names: Similarity
messages: Belongs to the heat shock protein 70 family.

876142:Eint 041140
gene id: 876142:Eint_041140
uniprot id: E0S6R8
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

876142:Eint 070630
gene id: 876142:Eint_070630
uniprot id: E0S7Z2
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

876142:Eint 071580
gene id: 876142:Eint_071580
uniprot id: E0S882
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

876142:Eint 060990
gene id: 876142:Eint_060990
uniprot id: E0S7M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC24 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

876142:Eint 061030
gene id: 876142:Eint_061030
uniprot id: E0S7N1
names: Similarity
messages: Belongs to the TFIIB family.

876142:Eint 071220
gene id: 876142:Eint_071220
uniprot id: E0S850
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

876142:Eint 111300
gene id: 876142:Eint_111300
uniprot id: E0SA07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EST3 family.
messages: Component of the telomerase complex involved in telomere replication. Stimulates RNA/DNA heteroduplex unwinding which favors the telomere replication by the telomerase.
messages: Nucleus
messages: telomere

876142:Eint 081470
gene id: 876142:Eint_081470
uniprot id: E0S8E2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

876142:Eint 081480
gene id: 876142:Eint_081480
uniprot id: E0S8E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

876142:Eint 030490
gene id: 876142:Eint_030490
uniprot id: E0S658
names: Similarity
messages: Belongs to the peptidase C19 family.

876142:Eint 031370
gene id: 876142:Eint_031370
uniprot id: E0S6E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Nucleus

876142:Eint 020160
gene id: 876142:Eint_020160
uniprot id: E0S5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

876142:Eint 030510
gene id: 876142:Eint_030510
uniprot id: E0S660
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 081410
gene id: 876142:Eint_081410
uniprot id: E0S8D6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

876142:Eint 061420
gene id: 876142:Eint_061420
uniprot id: E0S7R8
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

876142:Eint 090680
gene id: 876142:Eint_090680
uniprot id: E0S9D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

876142:Eint 090490
gene id: 876142:Eint_090490
uniprot id: E0S9B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Cytoplasm
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

876142:Eint 081740
gene id: 876142:Eint_081740
uniprot id: E0S8R8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

876142:Eint 021230
gene id: 876142:Eint_021230
uniprot id: E0S5Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.
messages: Nucleus

876142:Eint 051030
gene id: 876142:Eint_051030
uniprot id: E0S7C2
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

876142:Eint 081160
gene id: 876142:Eint_081160
uniprot id: E0S8T1
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

876142:Eint 090870
gene id: 876142:Eint_090870
uniprot id: E0S8V0
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

876142:Eint 030160
gene id: 876142:Eint_030160
uniprot id: E0S627
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

876142:Eint 060960
gene id: 876142:Eint_060960
uniprot id: E0S7M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

876142:Eint 051180
gene id: 876142:Eint_051180
uniprot id: E0S6X9
names: Similarity
messages: Belongs to the AAA ATPase family.

876142:Eint 090700
gene id: 876142:Eint_090700
uniprot id: E0S9D5
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 090970
gene id: 876142:Eint_090970
uniprot id: E0S8W0
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

876142:Eint 050800
gene id: 876142:Eint_050800
uniprot id: E0S7A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

876142:Eint 070820
gene id: 876142:Eint_070820
uniprot id: E0S811
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

876142:Eint 110095
gene id: 876142:Eint_110095
uniprot id: W8Q225
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS21 family.

876142:Eint 010990
gene id: 876142:Eint_010990
uniprot id: E0S5H6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

876142:Eint 050340
gene id: 876142:Eint_050340
uniprot id: E0S755
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

876142:Eint 081070
gene id: 876142:Eint_081070
uniprot id: E0S8Q3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

876142:Eint 100290
gene id: 876142:Eint_100290
uniprot id: E0S9H1
names: Similarity
messages: Belongs to the PPase family.

876142:Eint 111340
gene id: 876142:Eint_111340
uniprot id: E0SA11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: nuclear pore complex

876142:Eint 071010
gene id: 876142:Eint_071010
uniprot id: E0S829
names: Similarity
messages: Belongs to the NAD kinase family.

876142:Eint 010870
gene id: 876142:Eint_010870
uniprot id: E0S5G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

876142:Eint 081780
gene id: 876142:Eint_081780
uniprot id: E0S8A4
names: Similarity
messages: Belongs to the TBCC family.

876142:Eint 090440
gene id: 876142:Eint_090440
uniprot id: E0S9A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

876142:Eint 061470
gene id: 876142:Eint_061470
uniprot id: E0S7S3
names: Subcellular Location Annotation
messages: Membrane

876142:Eint 081120
gene id: 876142:Eint_081120
uniprot id: E0S8S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
messages: Nucleus

876142:Eint 040860
gene id: 876142:Eint_040860
uniprot id: E0S6P1
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

876142:Eint 040380
gene id: 876142:Eint_040380
uniprot id: E0S6J4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

876142:Eint 021310
gene id: 876142:Eint_021310
uniprot id: E0S5Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

876142:Eint 051450
gene id: 876142:Eint_051450
uniprot id: E0S706
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

876142:Eint 100985
gene id: 876142:Eint_100985
uniprot id: W8PKL1
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

876142:Eint 031430
gene id: 876142:Eint_031430
uniprot id: E0S6F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

876142:Eint 110390
gene id: 876142:Eint_110390
uniprot id: E0SAB4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

876142:Eint 031160
gene id: 876142:Eint_031160
uniprot id: E0S6C4
names: Similarity
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.

876142:Eint 040330
gene id: 876142:Eint_040330
uniprot id: E0S6I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

876142:Eint 060710
gene id: 876142:Eint_060710
uniprot id: E0S7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm

876142:Eint 060520
gene id: 876142:Eint_060520
uniprot id: E0S7I1
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

876142:Eint 090460
gene id: 876142:Eint_090460
uniprot id: E0S9B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Nucleus

876142:Eint 010490
gene id: 876142:Eint_010490
uniprot id: E0S5C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

876142:Eint 051160
gene id: 876142:Eint_051160
uniprot id: E0S6X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

876142:Eint 061050
gene id: 876142:Eint_061050
uniprot id: E0S7N3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

876142:Eint 091620
gene id: 876142:Eint_091620
uniprot id: E0S934
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

876142:Eint 021440
gene id: 876142:Eint_021440
uniprot id: E0S606
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

876142:Eint 040400
gene id: 876142:Eint_040400
uniprot id: E0S6J5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

876142:Eint 050920
gene id: 876142:Eint_050920
uniprot id: E0S7B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

876142:Eint 010510
gene id: 876142:Eint_010510
uniprot id: E0S5C9
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

876142:Eint 040515
gene id: 876142:Eint_040515
uniprot id: W8Q1U2
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

876142:Eint 090890
gene id: 876142:Eint_090890
uniprot id: E0S8V2
names: Similarity
messages: Belongs to the RAD52 family.

876142:Eint 021210
gene id: 876142:Eint_021210
uniprot id: E0S5Y3
names: Similarity
messages: Belongs to the TAF11 family.

876142:Eint 011050
gene id: 876142:Eint_011050
uniprot id: E0S5I2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

876142:Eint 020410
gene id: 876142:Eint_020410
uniprot id: E0S5Q7
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S1 family.

876142:Eint 100360
gene id: 876142:Eint_100360
uniprot id: E0S9H8
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

876142:Eint 101720
gene id: 876142:Eint_101720
uniprot id: E0S9W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

876142:Eint 070960
gene id: 876142:Eint_070960
uniprot id: E0S824
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

876142:Eint 101120
gene id: 876142:Eint_101120
uniprot id: E0S9Q2
names: Subcellular Location Annotation
messages: Nucleus

876142:Eint 040650
gene id: 876142:Eint_040650
uniprot id: E0S6M0
names: Similarity
messages: Belongs to the MPI phosphatase family.

876142:Eint 021360
gene id: 876142:Eint_021360
uniprot id: E0S5Z8
names: Function
messages: Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle.

876142:Eint 081090
gene id: 876142:Eint_081090
uniprot id: E0S8S4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

876142:Eint 090790
gene id: 876142:Eint_090790
uniprot id: E0S9E4
names: Similarity
messages: Belongs to the RNase PH family.

876142:Eint 020710
gene id: 876142:Eint_020710
uniprot id: E0S5T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids.
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex.
messages: Endoplasmic reticulum membrane

876142:Eint 071480
gene id: 876142:Eint_071480
uniprot id: E0S873
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

876142:Eint 041170
gene id: 876142:Eint_041170
uniprot id: E0S6S1
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

876142:Eint 021370
gene id: 876142:Eint_021370
uniprot id: E0S5Z9
names: Similarity
messages: Belongs to the Rab GDI family.

876142:Eint 090620
gene id: 876142:Eint_090620
uniprot id: E0S9C7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: Regulates also the sphingolipid metabolism.