871968:DESME RS04540
gene id: 871968:DESME_RS04540
uniprot id: W0EA90
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

871968:DESME RS00070
gene id: 871968:DESME_RS00070
uniprot id: W0E4M5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

871968:DESME RS06500
gene id: 871968:DESME_RS06500
uniprot id: W0EC74
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS04745
gene id: 871968:DESME_RS04745
uniprot id: W0E6T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

871968:DESME RS14285
gene id: 871968:DESME_RS14285
uniprot id: W0EGK2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

871968:DESME RS02550
gene id: 871968:DESME_RS02550
uniprot id: W0E5D9
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

871968:DESME RS10075
gene id: 871968:DESME_RS10075
uniprot id: W0EDZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

871968:DESME RS03460
gene id: 871968:DESME_RS03460
uniprot id: W0E5X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

871968:DESME RS11515
gene id: 871968:DESME_RS11515
uniprot id: W0EDT3
names: Similarity
messages: Belongs to the RemA family.

871968:DESME RS04550
gene id: 871968:DESME_RS04550
uniprot id: W0EB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

871968:DESME RS05070
gene id: 871968:DESME_RS05070
uniprot id: W0E6Z4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

871968:DESME RS10845
gene id: 871968:DESME_RS10845
uniprot id: W0E9H6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS12850
gene id: 871968:DESME_RS12850
uniprot id: W0EEG5
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

871968:DESME RS06615
gene id: 871968:DESME_RS06615
uniprot id: W0ECN0
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS09060
gene id: 871968:DESME_RS09060
uniprot id: W0E8S2
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

871968:DESME RS01850
gene id: 871968:DESME_RS01850
uniprot id: W0E5E2
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS05695
gene id: 871968:DESME_RS05695
uniprot id: W0E796
names: Similarity
messages: Belongs to the DEAD box helicase family.

871968:DESME RS03420
gene id: 871968:DESME_RS03420
uniprot id: W0E679
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

871968:DESME RS09680
gene id: 871968:DESME_RS09680
uniprot id: W0E9B5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS11345
gene id: 871968:DESME_RS11345
uniprot id: W0EEI6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

871968:DESME RS00800
gene id: 871968:DESME_RS00800
uniprot id: W0E4M3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

871968:DESME RS10780
gene id: 871968:DESME_RS10780
uniprot id: W0E9S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

871968:DESME RS06160
gene id: 871968:DESME_RS06160
uniprot id: W0ECF2
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

871968:DESME RS01670
gene id: 871968:DESME_RS01670
uniprot id: W0E5A4
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

871968:DESME RS10360
gene id: 871968:DESME_RS10360
uniprot id: W0E9M8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

871968:DESME RS11310
gene id: 871968:DESME_RS11310
uniprot id: W0EA27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

871968:DESME RS10735
gene id: 871968:DESME_RS10735
uniprot id: W0ED95
names: Similarity
messages: Belongs to the peptidase M16 family.

871968:DESME RS09505
gene id: 871968:DESME_RS09505
uniprot id: W0E8X4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

871968:DESME RS10730
gene id: 871968:DESME_RS10730
uniprot id: W0E9R5
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

871968:DESME RS13325
gene id: 871968:DESME_RS13325
uniprot id: W0EEP4
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS07340
gene id: 871968:DESME_RS07340
uniprot id: W0ED13
names: Similarity
messages: Belongs to the peptidase S11 family.

871968:DESME RS07465
gene id: 871968:DESME_RS07465
uniprot id: W0EBS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

871968:DESME RS01740
gene id: 871968:DESME_RS01740
uniprot id: W0EA69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

871968:DESME RS02335
gene id: 871968:DESME_RS02335
uniprot id: W0EAF8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

871968:DESME RS00195
gene id: 871968:DESME_RS00195
uniprot id: W0E4E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

871968:DESME RS08840
gene id: 871968:DESME_RS08840
uniprot id: W0EDS0
names: Similarity
messages: Belongs to the Ahb/Nir family.

871968:DESME RS04280
gene id: 871968:DESME_RS04280
uniprot id: W0EAZ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS01215
gene id: 871968:DESME_RS01215
uniprot id: W0E8L6
names: Similarity
messages: Belongs to the CtsR family.

871968:DESME RS11000
gene id: 871968:DESME_RS11000
uniprot id: W0E9X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

871968:DESME RS10680
gene id: 871968:DESME_RS10680
uniprot id: W0E9Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

871968:DESME RS05080
gene id: 871968:DESME_RS05080
uniprot id: W0EBF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS11030
gene id: 871968:DESME_RS11030
uniprot id: W0EDF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

871968:DESME RS00015
gene id: 871968:DESME_RS00015
uniprot id: W0E8Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

871968:DESME RS01600
gene id: 871968:DESME_RS01600
uniprot id: W0E8T2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS06475
gene id: 871968:DESME_RS06475
uniprot id: W0E7G3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

871968:DESME RS01750
gene id: 871968:DESME_RS01750
uniprot id: W0E8U9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

871968:DESME RS00765
gene id: 871968:DESME_RS00765
uniprot id: W0E8F8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

871968:DESME RS07130
gene id: 871968:DESME_RS07130
uniprot id: W0ECW7
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

871968:DESME RS10795
gene id: 871968:DESME_RS10795
uniprot id: W0E9G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

871968:DESME RS12040
gene id: 871968:DESME_RS12040
uniprot id: W0EA83
names: Similarity
messages: Belongs to the transglycosylase Slt family.

871968:DESME RS00310
gene id: 871968:DESME_RS00310
uniprot id: W0E944
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

871968:DESME RS04905
gene id: 871968:DESME_RS04905
uniprot id: W0EAF0
names: Similarity
messages: Belongs to the pirin family.

871968:DESME RS13710
gene id: 871968:DESME_RS13710
uniprot id: W0EG66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

871968:DESME RS06395
gene id: 871968:DESME_RS06395
uniprot id: W0ECJ5
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

871968:DESME RS13390
gene id: 871968:DESME_RS13390
uniprot id: W0EB68
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

871968:DESME RS06205
gene id: 871968:DESME_RS06205
uniprot id: W0EB54
names: Similarity
messages: Belongs to the glutamine synthetase family.

871968:DESME RS06780
gene id: 871968:DESME_RS06780
uniprot id: W0EBE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

871968:DESME RS09765
gene id: 871968:DESME_RS09765
uniprot id: W0EDT6
names: Similarity
messages: Belongs to the peptidase M24B family.

871968:DESME RS05760
gene id: 871968:DESME_RS05760
uniprot id: W0E737
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

871968:DESME RS01395
gene id: 871968:DESME_RS01395
uniprot id: W0E8Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

871968:DESME RS12330
gene id: 871968:DESME_RS12330
uniprot id: W0EAC3
names: Similarity
messages: Belongs to the MotB family.

871968:DESME RS12700
gene id: 871968:DESME_RS12700
uniprot id: W0EEE2
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS14865
gene id: 871968:DESME_RS14865
uniprot id: W0EGF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

871968:DESME RS07955
gene id: 871968:DESME_RS07955
uniprot id: W0EDB9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

871968:DESME RS11630
gene id: 871968:DESME_RS11630
uniprot id: W0EA18
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

871968:DESME RS05215
gene id: 871968:DESME_RS05215
uniprot id: W0E6P2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

871968:DESME RS05835
gene id: 871968:DESME_RS05835
uniprot id: W0EAZ3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

871968:DESME RS13360
gene id: 871968:DESME_RS13360
uniprot id: W0EG01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

871968:DESME RS11040
gene id: 871968:DESME_RS11040
uniprot id: W0E9M2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

871968:DESME RS03860
gene id: 871968:DESME_RS03860
uniprot id: W0E6F6
names: Similarity
messages: Belongs to the manganese catalase family.

871968:DESME RS11580
gene id: 871968:DESME_RS11580
uniprot id: W0EA08
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS01460
gene id: 871968:DESME_RS01460
uniprot id: W0EA24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

871968:DESME RS03500
gene id: 871968:DESME_RS03500
uniprot id: W0E9S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

871968:DESME RS10740
gene id: 871968:DESME_RS10740
uniprot id: W0EE72
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

871968:DESME RS13665
gene id: 871968:DESME_RS13665
uniprot id: W0EFS4
names: Similarity
messages: Belongs to the EamA transporter family.

871968:DESME RS14790
gene id: 871968:DESME_RS14790
uniprot id: W0EBN0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

871968:DESME RS05505
gene id: 871968:DESME_RS05505
uniprot id: W0EC21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

871968:DESME RS10120
gene id: 871968:DESME_RS10120
uniprot id: W0ED22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

871968:DESME RS01260
gene id: 871968:DESME_RS01260
uniprot id: W0E536
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

871968:DESME RS03990
gene id: 871968:DESME_RS03990
uniprot id: W0EA02
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

871968:DESME RS04765
gene id: 871968:DESME_RS04765
uniprot id: W0EBN5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

871968:DESME RS03150
gene id: 871968:DESME_RS03150
uniprot id: W0E5S5
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

871968:DESME RS01375
gene id: 871968:DESME_RS01375
uniprot id: W0E9I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

871968:DESME RS01390
gene id: 871968:DESME_RS01390
uniprot id: W0E558
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

871968:DESME RS10355
gene id: 871968:DESME_RS10355
uniprot id: W0EEG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

871968:DESME RS14820
gene id: 871968:DESME_RS14820
uniprot id: W0EGT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS10690
gene id: 871968:DESME_RS10690
uniprot id: W0EE63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

871968:DESME RS05085
gene id: 871968:DESME_RS05085
uniprot id: W0E6M3
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS09435
gene id: 871968:DESME_RS09435
uniprot id: W0EE10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

871968:DESME RS02925
gene id: 871968:DESME_RS02925
uniprot id: W0E5W6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

871968:DESME RS10755
gene id: 871968:DESME_RS10755
uniprot id: W0E9S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

871968:DESME RS14300
gene id: 871968:DESME_RS14300
uniprot id: W0EFA7
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS14915
gene id: 871968:DESME_RS14915
uniprot id: W0EGG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

871968:DESME RS11700
gene id: 871968:DESME_RS11700
uniprot id: W0EET1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

871968:DESME RS01540
gene id: 871968:DESME_RS01540
uniprot id: W0E586
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS10280
gene id: 871968:DESME_RS10280
uniprot id: W0ED43
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

871968:DESME RS01865
gene id: 871968:DESME_RS01865
uniprot id: W0E533
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS02030
gene id: 871968:DESME_RS02030
uniprot id: W0E8Z0
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

871968:DESME RS15065
gene id: 871968:DESME_RS15065
uniprot id: W0EFN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

871968:DESME RS01090
gene id: 871968:DESME_RS01090
uniprot id: W0E4Q5
names: Similarity
messages: Belongs to the AOR/FOR family.

871968:DESME RS11065
gene id: 871968:DESME_RS11065
uniprot id: W0E9M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

871968:DESME RS02765
gene id: 871968:DESME_RS02765
uniprot id: W0E9C5
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS09020
gene id: 871968:DESME_RS09020
uniprot id: W0EDH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

871968:DESME RS00565
gene id: 871968:DESME_RS00565
uniprot id: W0E975
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

871968:DESME RS12455
gene id: 871968:DESME_RS12455
uniprot id: W0EE94
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS11090
gene id: 871968:DESME_RS11090
uniprot id: W0E9N4
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

871968:DESME RS04255
gene id: 871968:DESME_RS04255
uniprot id: W0EAZ2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

871968:DESME RS05670
gene id: 871968:DESME_RS05670
uniprot id: W0E791
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

871968:DESME RS10395
gene id: 871968:DESME_RS10395
uniprot id: W0EE44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

871968:DESME RS01240
gene id: 871968:DESME_RS01240
uniprot id: W0E8M1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS10410
gene id: 871968:DESME_RS10410
uniprot id: W0E9P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

871968:DESME RS15030
gene id: 871968:DESME_RS15030
uniprot id: W0EGX5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

871968:DESME RS11295
gene id: 871968:DESME_RS11295
uniprot id: W0EEH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

871968:DESME RS00020
gene id: 871968:DESME_RS00020
uniprot id: W0E4B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

871968:DESME RS14715
gene id: 871968:DESME_RS14715
uniprot id: W0EGR6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

871968:DESME RS15070
gene id: 871968:DESME_RS15070
uniprot id: W0EGJ4
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS13240
gene id: 871968:DESME_RS13240
uniprot id: W0EB38
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

871968:DESME RS10040
gene id: 871968:DESME_RS10040
uniprot id: W0EDY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

871968:DESME RS08045
gene id: 871968:DESME_RS08045
uniprot id: W0EC33
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

871968:DESME RS08880
gene id: 871968:DESME_RS08880
uniprot id: W0EDF6
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS12665
gene id: 871968:DESME_RS12665
uniprot id: W0EFM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

871968:DESME RS09990
gene id: 871968:DESME_RS09990
uniprot id: W0EDX4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS04275
gene id: 871968:DESME_RS04275
uniprot id: W0EA46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

871968:DESME RS13485
gene id: 871968:DESME_RS13485
uniprot id: W0EFP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

871968:DESME RS03910
gene id: 871968:DESME_RS03910
uniprot id: W0E6G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

871968:DESME RS01775
gene id: 871968:DESME_RS01775
uniprot id: W0E8V4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

871968:DESME RS07460
gene id: 871968:DESME_RS07460
uniprot id: W0E890
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

871968:DESME RS14975
gene id: 871968:DESME_RS14975
uniprot id: W0EGW5
names: Similarity
messages: Belongs to the FemABX family.

871968:DESME RS09810
gene id: 871968:DESME_RS09810
uniprot id: W0EE74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS07575
gene id: 871968:DESME_RS07575
uniprot id: W0E8A6
names: Similarity
messages: Belongs to the EamA transporter family.

871968:DESME RS00430
gene id: 871968:DESME_RS00430
uniprot id: W0E8B8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

871968:DESME RS01330
gene id: 871968:DESME_RS01330
uniprot id: W0E4U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

871968:DESME RS12495
gene id: 871968:DESME_RS12495
uniprot id: W0EFJ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

871968:DESME RS09210
gene id: 871968:DESME_RS09210
uniprot id: W0EDK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

871968:DESME RS11455
gene id: 871968:DESME_RS11455
uniprot id: W0EF01
names: Similarity
messages: Belongs to the UPF0145 family.

871968:DESME RS11635
gene id: 871968:DESME_RS11635
uniprot id: W0EF58
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

871968:DESME RS12840
gene id: 871968:DESME_RS12840
uniprot id: W0EFQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

871968:DESME RS06340
gene id: 871968:DESME_RS06340
uniprot id: W0ECI5
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

871968:DESME RS11610
gene id: 871968:DESME_RS11610
uniprot id: W0EF53
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS00605
gene id: 871968:DESME_RS00605
uniprot id: W0E4U7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

871968:DESME RS15235
gene id: 871968:DESME_RS15235
uniprot id: W0EBU8
names: Similarity
messages: Belongs to the ParB family.

871968:DESME RS12155
gene id: 871968:DESME_RS12155
uniprot id: W0EAK4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

871968:DESME RS00595
gene id: 871968:DESME_RS00595
uniprot id: W0E4J8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

871968:DESME RS05515
gene id: 871968:DESME_RS05515
uniprot id: W0EAR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

871968:DESME RS05705
gene id: 871968:DESME_RS05705
uniprot id: W0EBS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

871968:DESME RS07560
gene id: 871968:DESME_RS07560
uniprot id: W0ECR8
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS13745
gene id: 871968:DESME_RS13745
uniprot id: W0EEX3
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

871968:DESME RS01425
gene id: 871968:DESME_RS01425
uniprot id: W0E9K0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

871968:DESME RS12950
gene id: 871968:DESME_RS12950
uniprot id: W0EEI1
names: Similarity
messages: Belongs to the UPF0758 family.

871968:DESME RS05555
gene id: 871968:DESME_RS05555
uniprot id: W0EC32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

871968:DESME RS13100
gene id: 871968:DESME_RS13100
uniprot id: W0EEL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

871968:DESME RS05425
gene id: 871968:DESME_RS05425
uniprot id: W0E6T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

871968:DESME RS10985
gene id: 871968:DESME_RS10985
uniprot id: W0EEC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

871968:DESME RS14515
gene id: 871968:DESME_RS14515
uniprot id: W0EGN0
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS03725
gene id: 871968:DESME_RS03725
uniprot id: W0EB73
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

871968:DESME RS11755
gene id: 871968:DESME_RS11755
uniprot id: W0EA40
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS04480
gene id: 871968:DESME_RS04480
uniprot id: W0EA81
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

871968:DESME RS02565
gene id: 871968:DESME_RS02565
uniprot id: W0E983
names: Similarity
messages: Belongs to the manganese catalase family.

871968:DESME RS02725
gene id: 871968:DESME_RS02725
uniprot id: W0EA66
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS12675
gene id: 871968:DESME_RS12675
uniprot id: W0EED7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

871968:DESME RS02410
gene id: 871968:DESME_RS02410
uniprot id: W0EAG8
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS04600
gene id: 871968:DESME_RS04600
uniprot id: W0E6R2
names: Subcellular Location Annotation
messages: Cytoplasm

871968:DESME RS08140
gene id: 871968:DESME_RS08140
uniprot id: W0EDF9
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

871968:DESME RS00165
gene id: 871968:DESME_RS00165
uniprot id: W0E914
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS13420
gene id: 871968:DESME_RS13420
uniprot id: W0EER1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

871968:DESME RS04680
gene id: 871968:DESME_RS04680
uniprot id: W0E6S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

871968:DESME RS05745
gene id: 871968:DESME_RS05745
uniprot id: W0E7C8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

871968:DESME RS09595
gene id: 871968:DESME_RS09595
uniprot id: W0EE40
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS09695
gene id: 871968:DESME_RS09695
uniprot id: W0E904
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

871968:DESME RS02955
gene id: 871968:DESME_RS02955
uniprot id: W0E9G4
names: Similarity
messages: Belongs to the HypE family.

871968:DESME RS04855
gene id: 871968:DESME_RS04855
uniprot id: W0EBB3
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

871968:DESME RS05995
gene id: 871968:DESME_RS05995
uniprot id: W0EB20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

871968:DESME RS11855
gene id: 871968:DESME_RS11855
uniprot id: W0EEW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

871968:DESME RS11575
gene id: 871968:DESME_RS11575
uniprot id: W0EEQ8
names: Similarity
messages: Belongs to the CpsD/CapB family.

871968:DESME RS12565
gene id: 871968:DESME_RS12565
uniprot id: W0EFK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

871968:DESME RS04285
gene id: 871968:DESME_RS04285
uniprot id: W0E6A0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

871968:DESME RS04025
gene id: 871968:DESME_RS04025
uniprot id: W0E662
names: Similarity
messages: Belongs to the EamA transporter family.

871968:DESME RS01605
gene id: 871968:DESME_RS01605
uniprot id: W0E9N1
names: Similarity
messages: Belongs to the UPF0251 family.

871968:DESME RS04445
gene id: 871968:DESME_RS04445
uniprot id: W0EBI6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

871968:DESME RS11695
gene id: 871968:DESME_RS11695
uniprot id: W0EDW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

871968:DESME RS13105
gene id: 871968:DESME_RS13105
uniprot id: W0EFI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

871968:DESME RS11985
gene id: 871968:DESME_RS11985
uniprot id: W0EA75
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

871968:DESME RS13005
gene id: 871968:DESME_RS13005
uniprot id: W0EFG2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

871968:DESME RS12595
gene id: 871968:DESME_RS12595
uniprot id: W0EAS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

871968:DESME RS01310
gene id: 871968:DESME_RS01310
uniprot id: W0E9Z6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

871968:DESME RS12185
gene id: 871968:DESME_RS12185
uniprot id: W0EE57
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

871968:DESME RS11685
gene id: 871968:DESME_RS11685
uniprot id: W0EF65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

871968:DESME RS11235
gene id: 871968:DESME_RS11235
uniprot id: W0EA12
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

871968:DESME RS12480
gene id: 871968:DESME_RS12480
uniprot id: W0EE98
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

871968:DESME RS01120
gene id: 871968:DESME_RS01120
uniprot id: W0E9W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

871968:DESME RS10260
gene id: 871968:DESME_RS10260
uniprot id: W0EE19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS14355
gene id: 871968:DESME_RS14355
uniprot id: W0EFB6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS03480
gene id: 871968:DESME_RS03480
uniprot id: W0EAM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

871968:DESME RS05430
gene id: 871968:DESME_RS05430
uniprot id: W0EC03
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS12855
gene id: 871968:DESME_RS12855
uniprot id: W0EFD1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

871968:DESME RS13000
gene id: 871968:DESME_RS13000
uniprot id: W0EEI8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

871968:DESME RS12290
gene id: 871968:DESME_RS12290
uniprot id: W0EAM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

871968:DESME RS13030
gene id: 871968:DESME_RS13030
uniprot id: W0EFG6
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS08775
gene id: 871968:DESME_RS08775
uniprot id: W0E8M7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS13160
gene id: 871968:DESME_RS13160
uniprot id: W0EFJ2
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

871968:DESME RS11710
gene id: 871968:DESME_RS11710
uniprot id: W0EF69
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

871968:DESME RS00580
gene id: 871968:DESME_RS00580
uniprot id: W0E4U4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS05465
gene id: 871968:DESME_RS05465
uniprot id: W0EAQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

871968:DESME RS05585
gene id: 871968:DESME_RS05585
uniprot id: W0EBP7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

871968:DESME RS12520
gene id: 871968:DESME_RS12520
uniprot id: W0EFK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

871968:DESME RS00155
gene id: 871968:DESME_RS00155
uniprot id: W0E4N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

871968:DESME RS07415
gene id: 871968:DESME_RS07415
uniprot id: W0EBR0
names: Similarity
messages: Belongs to the Tlp family.

871968:DESME RS14990
gene id: 871968:DESME_RS14990
uniprot id: W0EGH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

871968:DESME RS00435
gene id: 871968:DESME_RS00435
uniprot id: W0E966
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

871968:DESME RS13550
gene id: 871968:DESME_RS13550
uniprot id: W0EAZ0
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

871968:DESME RS03015
gene id: 871968:DESME_RS03015
uniprot id: W0EAD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

871968:DESME RS03385
gene id: 871968:DESME_RS03385
uniprot id: W0EB12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

871968:DESME RS07915
gene id: 871968:DESME_RS07915
uniprot id: W0EC04
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

871968:DESME RS09660
gene id: 871968:DESME_RS09660
uniprot id: W0EDR9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

871968:DESME RS03695
gene id: 871968:DESME_RS03695
uniprot id: W0E608
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

871968:DESME RS02665
gene id: 871968:DESME_RS02665
uniprot id: W0EA55
names: Similarity
messages: Belongs to the P(II) protein family.

871968:DESME RS03130
gene id: 871968:DESME_RS03130
uniprot id: W0E635
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

871968:DESME RS11660
gene id: 871968:DESME_RS11660
uniprot id: W0EF61
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

871968:DESME RS12130
gene id: 871968:DESME_RS12130
uniprot id: W0EAJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

871968:DESME RS14525
gene id: 871968:DESME_RS14525
uniprot id: W0EFD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

871968:DESME RS01265
gene id: 871968:DESME_RS01265
uniprot id: W0E8M6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS11270
gene id: 871968:DESME_RS11270
uniprot id: W0EEH3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

871968:DESME RS04140
gene id: 871968:DESME_RS04140
uniprot id: W0E6J5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

871968:DESME RS07320
gene id: 871968:DESME_RS07320
uniprot id: W0E865
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

871968:DESME RS03615
gene id: 871968:DESME_RS03615
uniprot id: W0E9T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

871968:DESME RS04395
gene id: 871968:DESME_RS04395
uniprot id: W0E6N0
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

871968:DESME RS11830
gene id: 871968:DESME_RS11830
uniprot id: W0EEV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

871968:DESME RS01650
gene id: 871968:DESME_RS01650
uniprot id: W0E9N6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

871968:DESME RS06895
gene id: 871968:DESME_RS06895
uniprot id: W0ECS6
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS01515
gene id: 871968:DESME_RS01515
uniprot id: W0E581
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

871968:DESME RS12615
gene id: 871968:DESME_RS12615
uniprot id: W0EAT3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

871968:DESME RS04845
gene id: 871968:DESME_RS04845
uniprot id: W0E6V6
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS07930
gene id: 871968:DESME_RS07930
uniprot id: W0EDB2
names: Similarity
messages: Belongs to the EamA transporter family.

871968:DESME RS13975
gene id: 871968:DESME_RS13975
uniprot id: W0EB67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

871968:DESME RS05500
gene id: 871968:DESME_RS05500
uniprot id: W0E6U5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

871968:DESME RS01755
gene id: 871968:DESME_RS01755
uniprot id: W0E9Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

871968:DESME RS05475
gene id: 871968:DESME_RS05475
uniprot id: W0E6U1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS01340
gene id: 871968:DESME_RS01340
uniprot id: W0E548
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

871968:DESME RS07170
gene id: 871968:DESME_RS07170
uniprot id: W0ECJ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

871968:DESME RS06560
gene id: 871968:DESME_RS06560
uniprot id: W0ECM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

871968:DESME RS05455
gene id: 871968:DESME_RS05455
uniprot id: W0EC09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

871968:DESME RS10815
gene id: 871968:DESME_RS10815
uniprot id: W0EE84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

871968:DESME RS03870
gene id: 871968:DESME_RS03870
uniprot id: W0EAT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

871968:DESME RS02710
gene id: 871968:DESME_RS02710
uniprot id: W0EH90
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

871968:DESME RS12710
gene id: 871968:DESME_RS12710
uniprot id: W0EAI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

871968:DESME RS05595
gene id: 871968:DESME_RS05595
uniprot id: W0EC38
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

871968:DESME RS03030
gene id: 871968:DESME_RS03030
uniprot id: W0E620
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS14900
gene id: 871968:DESME_RS14900
uniprot id: W0EGV0
names: Similarity
messages: Belongs to the UPF0340 family.

871968:DESME RS09685
gene id: 871968:DESME_RS09685
uniprot id: W0ECV0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

871968:DESME RS14410
gene id: 871968:DESME_RS14410
uniprot id: W0EGL9
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

871968:DESME RS00675
gene id: 871968:DESME_RS00675
uniprot id: W0E8E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

871968:DESME RS13110
gene id: 871968:DESME_RS13110
uniprot id: W0EFV9
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

871968:DESME RS06710
gene id: 871968:DESME_RS06710
uniprot id: W0EBD5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

871968:DESME RS10300
gene id: 871968:DESME_RS10300
uniprot id: W0E9L3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

871968:DESME RS12970
gene id: 871968:DESME_RS12970
uniprot id: W0EAY5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

871968:DESME RS09700
gene id: 871968:DESME_RS09700
uniprot id: W0EE58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

871968:DESME RS04470
gene id: 871968:DESME_RS04470
uniprot id: W0EBJ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS14265
gene id: 871968:DESME_RS14265
uniprot id: W0EBQ4
names: Similarity
messages: Belongs to the CdaR family.

871968:DESME RS09045
gene id: 871968:DESME_RS09045
uniprot id: W0EDI4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

871968:DESME RS00240
gene id: 871968:DESME_RS00240
uniprot id: W0E930
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

871968:DESME RS10850
gene id: 871968:DESME_RS10850
uniprot id: W0EEM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

871968:DESME RS00250
gene id: 871968:DESME_RS00250
uniprot id: W0E9J1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

871968:DESME RS09975
gene id: 871968:DESME_RS09975
uniprot id: W0EEA2
names: Similarity
messages: Belongs to the asp23 family.

871968:DESME RS12985
gene id: 871968:DESME_RS12985
uniprot id: W0EAN9
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS00010
gene id: 871968:DESME_RS00010
uniprot id: W0E843
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

871968:DESME RS01410
gene id: 871968:DESME_RS01410
uniprot id: W0EA15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

871968:DESME RS05690
gene id: 871968:DESME_RS05690
uniprot id: W0EC55
names: Function
names: Similarity
messages: Belongs to the CinA family.
messages: May be involved in the biosynthesis of molybdopterin.

871968:DESME RS00360
gene id: 871968:DESME_RS00360
uniprot id: W0E952
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

871968:DESME RS13295
gene id: 871968:DESME_RS13295
uniprot id: W0EB48
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS12515
gene id: 871968:DESME_RS12515
uniprot id: W0EAE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

871968:DESME RS05825
gene id: 871968:DESME_RS05825
uniprot id: W0ECA0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

871968:DESME RS08685
gene id: 871968:DESME_RS08685
uniprot id: W0EDQ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

871968:DESME RS09355
gene id: 871968:DESME_RS09355
uniprot id: W0E8V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

871968:DESME RS00105
gene id: 871968:DESME_RS00105
uniprot id: W0E4N0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

871968:DESME RS11595
gene id: 871968:DESME_RS11595
uniprot id: W0EDU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

871968:DESME RS07985
gene id: 871968:DESME_RS07985
uniprot id: W0EG94
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS10455
gene id: 871968:DESME_RS10455
uniprot id: W0EEI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

871968:DESME RS07230
gene id: 871968:DESME_RS07230
uniprot id: W0ECY8
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

871968:DESME RS09615
gene id: 871968:DESME_RS09615
uniprot id: W0E8Y9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS12815
gene id: 871968:DESME_RS12815
uniprot id: W0EFP9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

871968:DESME RS08810
gene id: 871968:DESME_RS08810
uniprot id: W0EDR6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

871968:DESME RS06515
gene id: 871968:DESME_RS06515
uniprot id: W0E7R0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

871968:DESME RS14150
gene id: 871968:DESME_RS14150
uniprot id: W0EG10
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

871968:DESME RS13895
gene id: 871968:DESME_RS13895
uniprot id: W0ED72
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS15950
gene id: 871968:DESME_RS15950
uniprot id: W0EBP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

871968:DESME RS11440
gene id: 871968:DESME_RS11440
uniprot id: W0EDN7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

871968:DESME RS14415
gene id: 871968:DESME_RS14415
uniprot id: W0EBS4
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

871968:DESME RS01480
gene id: 871968:DESME_RS01480
uniprot id: W0E4X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

871968:DESME RS14145
gene id: 871968:DESME_RS14145
uniprot id: W0EF41
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS00270
gene id: 871968:DESME_RS00270
uniprot id: W0E4F8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

871968:DESME RS11480
gene id: 871968:DESME_RS11480
uniprot id: W0EF18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

871968:DESME RS11085
gene id: 871968:DESME_RS11085
uniprot id: W0EEE3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

871968:DESME RS04375
gene id: 871968:DESME_RS04375
uniprot id: W0EA63
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

871968:DESME RS04380
gene id: 871968:DESME_RS04380
uniprot id: W0EB17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

871968:DESME RS10750
gene id: 871968:DESME_RS10750
uniprot id: W0EEK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

871968:DESME RS09585
gene id: 871968:DESME_RS09585
uniprot id: W0EDQ6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

871968:DESME RS06520
gene id: 871968:DESME_RS06520
uniprot id: W0EBA4
names: Similarity
messages: Belongs to the peptidase C40 family.

871968:DESME RS09040
gene id: 871968:DESME_RS09040
uniprot id: W0ECK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

871968:DESME RS14275
gene id: 871968:DESME_RS14275
uniprot id: W0EG58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

871968:DESME RS04490
gene id: 871968:DESME_RS04490
uniprot id: W0E6D8
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

871968:DESME RS07840
gene id: 871968:DESME_RS07840
uniprot id: W0EBY9
names: Similarity
messages: Belongs to the disproportionating enzyme family.

871968:DESME RS10870
gene id: 871968:DESME_RS10870
uniprot id: W0E9I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

871968:DESME RS00210
gene id: 871968:DESME_RS00210
uniprot id: W0E877
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

871968:DESME RS09455
gene id: 871968:DESME_RS09455
uniprot id: W0E8W8
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS05480
gene id: 871968:DESME_RS05480
uniprot id: W0EC15
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

871968:DESME RS04035
gene id: 871968:DESME_RS04035
uniprot id: W0E6I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

871968:DESME RS01505
gene id: 871968:DESME_RS01505
uniprot id: W0E4Y2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

871968:DESME RS10365
gene id: 871968:DESME_RS10365
uniprot id: W0ED63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

871968:DESME RS10800
gene id: 871968:DESME_RS10800
uniprot id: W0EEL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

871968:DESME RS07435
gene id: 871968:DESME_RS07435
uniprot id: W0E885
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

871968:DESME RS01715
gene id: 871968:DESME_RS01715
uniprot id: W0E8U5
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS00805
gene id: 871968:DESME_RS00805
uniprot id: W0E9S6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

871968:DESME RS09520
gene id: 871968:DESME_RS09520
uniprot id: W0ECS4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

871968:DESME RS04950
gene id: 871968:DESME_RS04950
uniprot id: W0EBS1
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS00045
gene id: 871968:DESME_RS00045
uniprot id: W0E4C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

871968:DESME RS11825
gene id: 871968:DESME_RS11825
uniprot id: W0EDY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

871968:DESME RS10335
gene id: 871968:DESME_RS10335
uniprot id: W0E9B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

871968:DESME RS06790
gene id: 871968:DESME_RS06790
uniprot id: W0E7M0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS13775
gene id: 871968:DESME_RS13775
uniprot id: W0EEY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

871968:DESME RS14130
gene id: 871968:DESME_RS14130
uniprot id: W0EGF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

871968:DESME RS11570
gene id: 871968:DESME_RS11570
uniprot id: W0EDU5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

871968:DESME RS03945
gene id: 871968:DESME_RS03945
uniprot id: W0EAU6
names: Similarity
messages: Belongs to the glutamine synthetase family.

871968:DESME RS01520
gene id: 871968:DESME_RS01520
uniprot id: W0E8S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

871968:DESME RS06825
gene id: 871968:DESME_RS06825
uniprot id: W0E7W8
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS11495
gene id: 871968:DESME_RS11495
uniprot id: W0EEM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

871968:DESME RS12995
gene id: 871968:DESME_RS12995
uniprot id: W0EAY9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

871968:DESME RS09800
gene id: 871968:DESME_RS09800
uniprot id: W0EDU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

871968:DESME RS03165
gene id: 871968:DESME_RS03165
uniprot id: W0E9L1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

871968:DESME RS14890
gene id: 871968:DESME_RS14890
uniprot id: W0EGG3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

871968:DESME RS09840
gene id: 871968:DESME_RS09840
uniprot id: W0E9D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

871968:DESME RS05290
gene id: 871968:DESME_RS05290
uniprot id: W0E6Q2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

871968:DESME RS03225
gene id: 871968:DESME_RS03225
uniprot id: W0EAH8
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

871968:DESME RS09035
gene id: 871968:DESME_RS09035
uniprot id: W0E917
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

871968:DESME RS02340
gene id: 871968:DESME_RS02340
uniprot id: W0E5L8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

871968:DESME RS00840
gene id: 871968:DESME_RS00840
uniprot id: W0E8G8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

871968:DESME RS01230
gene id: 871968:DESME_RS01230
uniprot id: W0E9Y4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

871968:DESME RS14215
gene id: 871968:DESME_RS14215
uniprot id: W0EBP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

871968:DESME RS02620
gene id: 871968:DESME_RS02620
uniprot id: W0E5F5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

871968:DESME RS06090
gene id: 871968:DESME_RS06090
uniprot id: W0E7I5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

871968:DESME RS12120
gene id: 871968:DESME_RS12120
uniprot id: W0EA92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

871968:DESME RS06540
gene id: 871968:DESME_RS06540
uniprot id: W0E7R5
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

871968:DESME RS00610
gene id: 871968:DESME_RS00610
uniprot id: W0E8D6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

871968:DESME RS00050
gene id: 871968:DESME_RS00050
uniprot id: W0E9G3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS12650
gene id: 871968:DESME_RS12650
uniprot id: W0EED2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

871968:DESME RS14555
gene id: 871968:DESME_RS14555
uniprot id: W0EGA5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

871968:DESME RS08015
gene id: 871968:DESME_RS08015
uniprot id: W0E8J8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS07120
gene id: 871968:DESME_RS07120
uniprot id: W0ECI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

871968:DESME RS12325
gene id: 871968:DESME_RS12325
uniprot id: W0EF48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

871968:DESME RS14695
gene id: 871968:DESME_RS14695
uniprot id: W0EBW1
names: Subcellular Location Annotation
messages: Cytoplasm

871968:DESME RS11390
gene id: 871968:DESME_RS11390
uniprot id: W0EDM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

871968:DESME RS05675
gene id: 871968:DESME_RS05675
uniprot id: W0EAT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

871968:DESME RS14540
gene id: 871968:DESME_RS14540
uniprot id: W0EGN3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

871968:DESME RS08210
gene id: 871968:DESME_RS08210
uniprot id: W0ED52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

871968:DESME RS04370
gene id: 871968:DESME_RS04370
uniprot id: W0E6M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

871968:DESME RS07100
gene id: 871968:DESME_RS07100
uniprot id: W0E7S6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

871968:DESME RS05095
gene id: 871968:DESME_RS05095
uniprot id: W0E700
names: Similarity
messages: Belongs to the UPF0173 family.

871968:DESME RS06935
gene id: 871968:DESME_RS06935
uniprot id: W0ECE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

871968:DESME RS11965
gene id: 871968:DESME_RS11965
uniprot id: W0EFA8
names: Similarity
messages: Belongs to the peptidase U62 family.

871968:DESME RS11080
gene id: 871968:DESME_RS11080
uniprot id: W0EDG8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

871968:DESME RS02380
gene id: 871968:DESME_RS02380
uniprot id: W0E5M2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

871968:DESME RS07880
gene id: 871968:DESME_RS07880
uniprot id: W0EDA2
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

871968:DESME RS14885
gene id: 871968:DESME_RS14885
uniprot id: W0EFK4
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

871968:DESME RS06495
gene id: 871968:DESME_RS06495
uniprot id: W0EBA1
names: Similarity
messages: Belongs to the UxaA family.

871968:DESME RS04355
gene id: 871968:DESME_RS04355
uniprot id: W0EB13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS02655
gene id: 871968:DESME_RS02655
uniprot id: W0E5S2
names: Similarity
messages: Belongs to the P(II) protein family.

871968:DESME RS12810
gene id: 871968:DESME_RS12810
uniprot id: W0EAK5
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS01685
gene id: 871968:DESME_RS01685
uniprot id: W0E507
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

871968:DESME RS07325
gene id: 871968:DESME_RS07325
uniprot id: W0EBP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

871968:DESME RS06285
gene id: 871968:DESME_RS06285
uniprot id: W0EB65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

871968:DESME RS11405
gene id: 871968:DESME_RS11405
uniprot id: W0EEY9
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS01690
gene id: 871968:DESME_RS01690
uniprot id: W0EA59
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

871968:DESME RS13900
gene id: 871968:DESME_RS13900
uniprot id: W0EGR8
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS03490
gene id: 871968:DESME_RS03490
uniprot id: W0EB31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

871968:DESME RS07105
gene id: 871968:DESME_RS07105
uniprot id: W0ECW3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

871968:DESME RS04150
gene id: 871968:DESME_RS04150
uniprot id: W0EAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

871968:DESME RS05685
gene id: 871968:DESME_RS05685
uniprot id: W0E6X9
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

871968:DESME RS09515
gene id: 871968:DESME_RS09515
uniprot id: W0E988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

871968:DESME RS12630
gene id: 871968:DESME_RS12630
uniprot id: W0EAH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

871968:DESME RS10990
gene id: 871968:DESME_RS10990
uniprot id: W0E9L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

871968:DESME RS12915
gene id: 871968:DESME_RS12915
uniprot id: W0EFS0
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

871968:DESME RS12110
gene id: 871968:DESME_RS12110
uniprot id: W0EE43
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

871968:DESME RS01695
gene id: 871968:DESME_RS01695
uniprot id: W0E5A9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

871968:DESME RS06645
gene id: 871968:DESME_RS06645
uniprot id: W0ECN5
names: Subcellular Location Annotation
messages: Cell membrane

871968:DESME RS06815
gene id: 871968:DESME_RS06815
uniprot id: W0E7M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

871968:DESME RS06140
gene id: 871968:DESME_RS06140
uniprot id: W0E7J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

871968:DESME RS14030
gene id: 871968:DESME_RS14030
uniprot id: W0EGD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

871968:DESME RS04895
gene id: 871968:DESME_RS04895
uniprot id: W0EBQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Membrane

871968:DESME RS14850
gene id: 871968:DESME_RS14850
uniprot id: W0EGU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

871968:DESME RS13410
gene id: 871968:DESME_RS13410
uniprot id: W0EG12
names: Similarity
messages: Belongs to the UPF0237 family.

871968:DESME RS02530
gene id: 871968:DESME_RS02530
uniprot id: W0EAJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

871968:DESME RS15150
gene id: 871968:DESME_RS15150
uniprot id: W0EFP3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

871968:DESME RS03450
gene id: 871968:DESME_RS03450
uniprot id: W0E9R1
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS12820
gene id: 871968:DESME_RS12820
uniprot id: W0EAV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

871968:DESME RS03800
gene id: 871968:DESME_RS03800
uniprot id: W0EB88
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

871968:DESME RS01055
gene id: 871968:DESME_RS01055
uniprot id: W0E8J0
names: Similarity
messages: Belongs to the YggT family.

871968:DESME RS13075
gene id: 871968:DESME_RS13075
uniprot id: W0EEK6
names: Similarity
messages: Belongs to the TrpF family.

871968:DESME RS04810
gene id: 871968:DESME_RS04810
uniprot id: W0E6I4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

871968:DESME RS13645
gene id: 871968:DESME_RS13645
uniprot id: W0EB09
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS13535
gene id: 871968:DESME_RS13535
uniprot id: W0EET4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

871968:DESME RS12645
gene id: 871968:DESME_RS12645
uniprot id: W0EAT6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

871968:DESME RS00040
gene id: 871968:DESME_RS00040
uniprot id: W0E8Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

871968:DESME RS10245
gene id: 871968:DESME_RS10245
uniprot id: W0E999
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

871968:DESME RS08860
gene id: 871968:DESME_RS08860
uniprot id: W0E8P3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

871968:DESME RS14930
gene id: 871968:DESME_RS14930
uniprot id: W0EC06
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

871968:DESME RS00370
gene id: 871968:DESME_RS00370
uniprot id: W0E9L4
names: Similarity
messages: Belongs to the UPF0749 family.

871968:DESME RS03110
gene id: 871968:DESME_RS03110
uniprot id: W0E9K2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

871968:DESME RS09850
gene id: 871968:DESME_RS09850
uniprot id: W0EDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

871968:DESME RS11925
gene id: 871968:DESME_RS11925
uniprot id: W0EE07
names: Similarity
messages: Belongs to the Fur family.

871968:DESME RS07250
gene id: 871968:DESME_RS07250
uniprot id: W0E852
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

871968:DESME RS15195
gene id: 871968:DESME_RS15195
uniprot id: W0EC56
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS14345
gene id: 871968:DESME_RS14345
uniprot id: W0EBR6
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS13770
gene id: 871968:DESME_RS13770
uniprot id: W0EBD4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

871968:DESME RS13505
gene id: 871968:DESME_RS13505
uniprot id: W0EES9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

871968:DESME RS01415
gene id: 871968:DESME_RS01415
uniprot id: W0E563
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

871968:DESME RS03425
gene id: 871968:DESME_RS03425
uniprot id: W0E9Q6
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

871968:DESME RS07775
gene id: 871968:DESME_RS07775
uniprot id: W0E844
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

871968:DESME RS01475
gene id: 871968:DESME_RS01475
uniprot id: W0E9L2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

871968:DESME RS00885
gene id: 871968:DESME_RS00885
uniprot id: W0E8H2
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

871968:DESME RS00835
gene id: 871968:DESME_RS00835
uniprot id: W0E4Y3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

871968:DESME RS03005
gene id: 871968:DESME_RS03005
uniprot id: W0E618
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS12385
gene id: 871968:DESME_RS12385
uniprot id: W0EFI3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

871968:DESME RS02495
gene id: 871968:DESME_RS02495
uniprot id: W0EAI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

871968:DESME RS14550
gene id: 871968:DESME_RS14550
uniprot id: W0EFE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

871968:DESME RS10980
gene id: 871968:DESME_RS10980
uniprot id: W0EDE5
names: Similarity
messages: Belongs to the UPF0102 family.

871968:DESME RS12975
gene id: 871968:DESME_RS12975
uniprot id: W0EEI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

871968:DESME RS07480
gene id: 871968:DESME_RS07480
uniprot id: W0E7Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

871968:DESME RS14290
gene id: 871968:DESME_RS14290
uniprot id: W0EBQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS04485
gene id: 871968:DESME_RS04485
uniprot id: W0EB41
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

871968:DESME RS09390
gene id: 871968:DESME_RS09390
uniprot id: W0E964
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

871968:DESME RS04975
gene id: 871968:DESME_RS04975
uniprot id: W0EBS7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

871968:DESME RS04000
gene id: 871968:DESME_RS04000
uniprot id: W0E656
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

871968:DESME RS12585
gene id: 871968:DESME_RS12585
uniprot id: W0EAG4
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS01370
gene id: 871968:DESME_RS01370
uniprot id: W0E8P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

871968:DESME RS01280
gene id: 871968:DESME_RS01280
uniprot id: W0E9Z2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

871968:DESME RS13235
gene id: 871968:DESME_RS13235
uniprot id: W0EFX8
names: Similarity
messages: Belongs to the class-I fumarase family.

871968:DESME RS01560
gene id: 871968:DESME_RS01560
uniprot id: W0E9M6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS04535
gene id: 871968:DESME_RS04535
uniprot id: W0E6Q3
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

871968:DESME RS08315
gene id: 871968:DESME_RS08315
uniprot id: W0ED76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

871968:DESME RS15255
gene id: 871968:DESME_RS15255
uniprot id: W0EGM4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS10225
gene id: 871968:DESME_RS10225
uniprot id: W0EEE1
names: Similarity
messages: Belongs to the UPF0473 family.

871968:DESME RS04665
gene id: 871968:DESME_RS04665
uniprot id: W0EB75
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

871968:DESME RS04500
gene id: 871968:DESME_RS04500
uniprot id: W0E6P8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

871968:DESME RS05980
gene id: 871968:DESME_RS05980
uniprot id: W0E777
names: Similarity
messages: Belongs to the threonine synthase family.

871968:DESME RS00630
gene id: 871968:DESME_RS00630
uniprot id: W0E4V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

871968:DESME RS10285
gene id: 871968:DESME_RS10285
uniprot id: W0EE25
names: Similarity
messages: Belongs to the thioredoxin family.

871968:DESME RS07225
gene id: 871968:DESME_RS07225
uniprot id: W0E7V1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

871968:DESME RS08055
gene id: 871968:DESME_RS08055
uniprot id: W0E8A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

871968:DESME RS09305
gene id: 871968:DESME_RS09305
uniprot id: W0E8U7
names: Similarity
messages: Belongs to the UPF0735 family.

871968:DESME RS14570
gene id: 871968:DESME_RS14570
uniprot id: W0EBU3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

871968:DESME RS08120
gene id: 871968:DESME_RS08120
uniprot id: W0E8L8
names: Similarity
messages: Belongs to the EamA transporter family.

871968:DESME RS07940
gene id: 871968:DESME_RS07940
uniprot id: W0EC10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

871968:DESME RS09820
gene id: 871968:DESME_RS09820
uniprot id: W0ECX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

871968:DESME RS05125
gene id: 871968:DESME_RS05125
uniprot id: W0E705
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

871968:DESME RS03925
gene id: 871968:DESME_RS03925
uniprot id: W0E644
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS11505
gene id: 871968:DESME_RS11505
uniprot id: W0EF35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

871968:DESME RS04460
gene id: 871968:DESME_RS04460
uniprot id: W0EB34
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

871968:DESME RS09860
gene id: 871968:DESME_RS09860
uniprot id: W0EE83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

871968:DESME RS13530
gene id: 871968:DESME_RS13530
uniprot id: W0EB97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

871968:DESME RS01455
gene id: 871968:DESME_RS01455
uniprot id: W0E4X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

871968:DESME RS00030
gene id: 871968:DESME_RS00030
uniprot id: W0E4M1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

871968:DESME RS02935
gene id: 871968:DESME_RS02935
uniprot id: W0EA95
names: Similarity
messages: Belongs to the ThiD family.

871968:DESME RS01770
gene id: 871968:DESME_RS01770
uniprot id: W0E5C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

871968:DESME RS02930
gene id: 871968:DESME_RS02930
uniprot id: W0E9E5
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

871968:DESME RS01345
gene id: 871968:DESME_RS01345
uniprot id: W0E8P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

871968:DESME RS02745
gene id: 871968:DESME_RS02745
uniprot id: W0E9C1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS14660
gene id: 871968:DESME_RS14660
uniprot id: W0EBL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

871968:DESME RS10460
gene id: 871968:DESME_RS10460
uniprot id: W0E9P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

871968:DESME RS02625
gene id: 871968:DESME_RS02625
uniprot id: W0EAL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

871968:DESME RS00115
gene id: 871968:DESME_RS00115
uniprot id: W0E906
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

871968:DESME RS11835
gene id: 871968:DESME_RS11835
uniprot id: W0EA52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

871968:DESME RS04965
gene id: 871968:DESME_RS04965
uniprot id: W0EBD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

871968:DESME RS12310
gene id: 871968:DESME_RS12310
uniprot id: W0EFG9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

871968:DESME RS11740
gene id: 871968:DESME_RS11740
uniprot id: W0EAD2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

871968:DESME RS04510
gene id: 871968:DESME_RS04510
uniprot id: W0EB47
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

871968:DESME RS13275
gene id: 871968:DESME_RS13275
uniprot id: W0EEN7
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS12640
gene id: 871968:DESME_RS12640
uniprot id: W0EFM0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

871968:DESME RS13185
gene id: 871968:DESME_RS13185
uniprot id: W0EFW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

871968:DESME RS08890
gene id: 871968:DESME_RS08890
uniprot id: W0EDS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

871968:DESME RS12580
gene id: 871968:DESME_RS12580
uniprot id: W0EF81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

871968:DESME RS04125
gene id: 871968:DESME_RS04125
uniprot id: W0E681
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

871968:DESME RS01680
gene id: 871968:DESME_RS01680
uniprot id: W0E9P1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

871968:DESME RS01430
gene id: 871968:DESME_RS01430
uniprot id: W0E4W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

871968:DESME RS00640
gene id: 871968:DESME_RS00640
uniprot id: W0E987
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

871968:DESME RS03965
gene id: 871968:DESME_RS03965
uniprot id: W0E9Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

871968:DESME RS04475
gene id: 871968:DESME_RS04475
uniprot id: W0E6P3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

871968:DESME RS09500
gene id: 871968:DESME_RS09500
uniprot id: W0EDP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

871968:DESME RS08675
gene id: 871968:DESME_RS08675
uniprot id: W0EDD1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

871968:DESME RS10190
gene id: 871968:DESME_RS10190
uniprot id: W0EE03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

871968:DESME RS12060
gene id: 871968:DESME_RS12060
uniprot id: W0EF04
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

871968:DESME RS06250
gene id: 871968:DESME_RS06250
uniprot id: W0ECB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm

871968:DESME RS14185
gene id: 871968:DESME_RS14185
uniprot id: W0EGH4
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS12115
gene id: 871968:DESME_RS12115
uniprot id: W0EF13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

871968:DESME RS01485
gene id: 871968:DESME_RS01485
uniprot id: W0EA28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

871968:DESME RS02560
gene id: 871968:DESME_RS02560
uniprot id: W0E5Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

871968:DESME RS13620
gene id: 871968:DESME_RS13620
uniprot id: W0EB02
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

871968:DESME RS09320
gene id: 871968:DESME_RS09320
uniprot id: W0ECP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

871968:DESME RS09010
gene id: 871968:DESME_RS09010
uniprot id: W0E912
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

871968:DESME RS07430
gene id: 871968:DESME_RS07430
uniprot id: W0ED24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

871968:DESME RS09395
gene id: 871968:DESME_RS09395
uniprot id: W0ECQ4
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

871968:DESME RS01530
gene id: 871968:DESME_RS01530
uniprot id: W0E4Y8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

871968:DESME RS01700
gene id: 871968:DESME_RS01700
uniprot id: W0E8U2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS14115
gene id: 871968:DESME_RS14115
uniprot id: W0EF36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

871968:DESME RS10145
gene id: 871968:DESME_RS10145
uniprot id: W0ED26
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

871968:DESME RS13315
gene id: 871968:DESME_RS13315
uniprot id: W0EFZ1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS06350
gene id: 871968:DESME_RS06350
uniprot id: W0EB78
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS12655
gene id: 871968:DESME_RS12655
uniprot id: W0EF95
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

871968:DESME RS08900
gene id: 871968:DESME_RS08900
uniprot id: W0ECI4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

871968:DESME RS07280
gene id: 871968:DESME_RS07280
uniprot id: W0ECM3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

871968:DESME RS14495
gene id: 871968:DESME_RS14495
uniprot id: W0EBT2
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS14945
gene id: 871968:DESME_RS14945
uniprot id: W0EBQ2
names: Similarity
messages: Belongs to the FBPase class 2 family.

871968:DESME RS05510
gene id: 871968:DESME_RS05510
uniprot id: W0E763
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

871968:DESME RS15040
gene id: 871968:DESME_RS15040
uniprot id: W0EFM6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

871968:DESME RS11900
gene id: 871968:DESME_RS11900
uniprot id: W0EE05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

871968:DESME RS06690
gene id: 871968:DESME_RS06690
uniprot id: W0ECA3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

871968:DESME RS02660
gene id: 871968:DESME_RS02660
uniprot id: W0E9A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

871968:DESME RS13230
gene id: 871968:DESME_RS13230
uniprot id: W0EAT1
names: Similarity
messages: Belongs to the class-I fumarase family.

871968:DESME RS12830
gene id: 871968:DESME_RS12830
uniprot id: W0EFC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

871968:DESME RS12920
gene id: 871968:DESME_RS12920
uniprot id: W0EAX5
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

871968:DESME RS05150
gene id: 871968:DESME_RS05150
uniprot id: W0EBV4
names: Similarity
messages: Belongs to the EamA transporter family.

871968:DESME RS07680
gene id: 871968:DESME_RS07680
uniprot id: W0ED61
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

871968:DESME RS00375
gene id: 871968:DESME_RS00375
uniprot id: W0E4S2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

871968:DESME RS02680
gene id: 871968:DESME_RS02680
uniprot id: W0E5S8
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS04870
gene id: 871968:DESME_RS04870
uniprot id: W0E6W0
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS07860
gene id: 871968:DESME_RS07860
uniprot id: W0E8H1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

871968:DESME RS06005
gene id: 871968:DESME_RS06005
uniprot id: W0E782
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

871968:DESME RS14240
gene id: 871968:DESME_RS14240
uniprot id: W0EBQ1
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

871968:DESME RS00440
gene id: 871968:DESME_RS00440
uniprot id: W0E4I7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

871968:DESME RS15270
gene id: 871968:DESME_RS15270
uniprot id: W0EC68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

871968:DESME RS12870
gene id: 871968:DESME_RS12870
uniprot id: W0EAW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

871968:DESME RS09960
gene id: 871968:DESME_RS09960
uniprot id: W0ECZ6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

871968:DESME RS06685
gene id: 871968:DESME_RS06685
uniprot id: W0EBD0
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

871968:DESME RS03445
gene id: 871968:DESME_RS03445
uniprot id: W0E686
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

871968:DESME RS11690
gene id: 871968:DESME_RS11690
uniprot id: W0EAC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

871968:DESME RS10415
gene id: 871968:DESME_RS10415
uniprot id: W0ED73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

871968:DESME RS11370
gene id: 871968:DESME_RS11370
uniprot id: W0EEJ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

871968:DESME RS01440
gene id: 871968:DESME_RS01440
uniprot id: W0E567
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

871968:DESME RS03305
gene id: 871968:DESME_RS03305
uniprot id: W0EAJ3
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

871968:DESME RS03950
gene id: 871968:DESME_RS03950
uniprot id: W0E648
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS11865
gene id: 871968:DESME_RS11865
uniprot id: W0EF92
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS03035
gene id: 871968:DESME_RS03035
uniprot id: W0E9I6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS04985
gene id: 871968:DESME_RS04985
uniprot id: W0EAG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

871968:DESME RS09175
gene id: 871968:DESME_RS09175
uniprot id: G6GH15
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

871968:DESME RS04670
gene id: 871968:DESME_RS04670
uniprot id: W0E6G4
names: Similarity
messages: Belongs to the GerABKA family.

871968:DESME RS03465
gene id: 871968:DESME_RS03465
uniprot id: W0EB26
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

871968:DESME RS12535
gene id: 871968:DESME_RS12535
uniprot id: W0EF74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

871968:DESME RS15120
gene id: 871968:DESME_RS15120
uniprot id: W0EC42
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

871968:DESME RS11500
gene id: 871968:DESME_RS11500
uniprot id: W0E9Y0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS10695
gene id: 871968:DESME_RS10695
uniprot id: W0E9E9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

871968:DESME RS07960
gene id: 871968:DESME_RS07960
uniprot id: W0E8I9
names: Similarity
messages: Belongs to the citrate synthase family.

871968:DESME RS14580
gene id: 871968:DESME_RS14580
uniprot id: W0EGB0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

871968:DESME RS10930
gene id: 871968:DESME_RS10930
uniprot id: W0EDD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

871968:DESME RS10035
gene id: 871968:DESME_RS10035
uniprot id: W0ED10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

871968:DESME RS14860
gene id: 871968:DESME_RS14860
uniprot id: W0EFJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

871968:DESME RS03760
gene id: 871968:DESME_RS03760
uniprot id: W0E9W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

871968:DESME RS11625
gene id: 871968:DESME_RS11625
uniprot id: W0EER9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

871968:DESME RS11535
gene id: 871968:DESME_RS11535
uniprot id: W0EAA3
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

871968:DESME RS00080
gene id: 871968:DESME_RS00080
uniprot id: W0E851
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS15275
gene id: 871968:DESME_RS15275
uniprot id: W0EFR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

871968:DESME RS00590
gene id: 871968:DESME_RS00590
uniprot id: W0E979
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

871968:DESME RS11785
gene id: 871968:DESME_RS11785
uniprot id: W0EF80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

871968:DESME RS08360
gene id: 871968:DESME_RS08360
uniprot id: W0ECB1
names: Similarity
messages: Belongs to the PspA/IM30 family.

871968:DESME RS06705
gene id: 871968:DESME_RS06705
uniprot id: W0E7U6
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS00870
gene id: 871968:DESME_RS00870
uniprot id: W0E4N1
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

871968:DESME RS15245
gene id: 871968:DESME_RS15245
uniprot id: W0EC64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

871968:DESME RS10830
gene id: 871968:DESME_RS10830
uniprot id: W0E9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

871968:DESME RS08665
gene id: 871968:DESME_RS08665
uniprot id: W0E8W6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

871968:DESME RS09845
gene id: 871968:DESME_RS09845
uniprot id: W0ECX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

871968:DESME RS04955
gene id: 871968:DESME_RS04955
uniprot id: W0E6X7
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS02485
gene id: 871968:DESME_RS02485
uniprot id: W0EA14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

871968:DESME RS09710
gene id: 871968:DESME_RS09710
uniprot id: W0ECV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

871968:DESME RS05200
gene id: 871968:DESME_RS05200
uniprot id: W0EAK3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

871968:DESME RS00260
gene id: 871968:DESME_RS00260
uniprot id: W0E884
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

871968:DESME RS03535
gene id: 871968:DESME_RS03535
uniprot id: W0E5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

871968:DESME RS04130
gene id: 871968:DESME_RS04130
uniprot id: W0EBE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

871968:DESME RS11465
gene id: 871968:DESME_RS11465
uniprot id: W0EDP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

871968:DESME RS12660
gene id: 871968:DESME_RS12660
uniprot id: W0EAH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

871968:DESME RS02585
gene id: 871968:DESME_RS02585
uniprot id: W0E990
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

871968:DESME RS06360
gene id: 871968:DESME_RS06360
uniprot id: W0E7E5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

871968:DESME RS14135
gene id: 871968:DESME_RS14135
uniprot id: W0EBK4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

871968:DESME RS10385
gene id: 871968:DESME_RS10385
uniprot id: W0E9N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

871968:DESME RS09815
gene id: 871968:DESME_RS09815
uniprot id: W0E9D6
names: Similarity
messages: Belongs to the TlyA family.

871968:DESME RS01315
gene id: 871968:DESME_RS01315
uniprot id: W0E545
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

871968:DESME RS00095
gene id: 871968:DESME_RS00095
uniprot id: W0E4C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

871968:DESME RS01290
gene id: 871968:DESME_RS01290
uniprot id: W0E8M9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

871968:DESME RS08595
gene id: 871968:DESME_RS08595
uniprot id: W0ECG9
names: Similarity
messages: Belongs to the RuvC family.

871968:DESME RS11820
gene id: 871968:DESME_RS11820
uniprot id: W0EAE4
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS05210
gene id: 871968:DESME_RS05210
uniprot id: W0EBH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

871968:DESME RS10855
gene id: 871968:DESME_RS10855
uniprot id: W0E9U2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

871968:DESME RS11335
gene id: 871968:DESME_RS11335
uniprot id: W0EA33
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

871968:DESME RS13930
gene id: 871968:DESME_RS13930
uniprot id: W0EGA8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

871968:DESME RS07125
gene id: 871968:DESME_RS07125
uniprot id: W0E7T0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

871968:DESME RS06470
gene id: 871968:DESME_RS06470
uniprot id: W0EC69
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

871968:DESME RS06145
gene id: 871968:DESME_RS06145
uniprot id: W0EB44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

871968:DESME RS03100
gene id: 871968:DESME_RS03100
uniprot id: W0EAW7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

871968:DESME RS08115
gene id: 871968:DESME_RS08115
uniprot id: W0EDF3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

871968:DESME RS03970
gene id: 871968:DESME_RS03970
uniprot id: W0EAV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

871968:DESME RS07330
gene id: 871968:DESME_RS07330
uniprot id: W0ECN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

871968:DESME RS05375
gene id: 871968:DESME_RS05375
uniprot id: W0E6R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

871968:DESME RS03920
gene id: 871968:DESME_RS03920
uniprot id: W0EAU4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

871968:DESME RS10325
gene id: 871968:DESME_RS10325
uniprot id: W0ED53
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

871968:DESME RS00385
gene id: 871968:DESME_RS00385
uniprot id: W0E957
names: Similarity
messages: Belongs to the DHPS family.

871968:DESME RS06980
gene id: 871968:DESME_RS06980
uniprot id: W0EBI2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

871968:DESME RS10825
gene id: 871968:DESME_RS10825
uniprot id: W0EEL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

871968:DESME RS04830
gene id: 871968:DESME_RS04830
uniprot id: W0EBA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

871968:DESME RS06970
gene id: 871968:DESME_RS06970
uniprot id: W0ECT9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

871968:DESME RS10215
gene id: 871968:DESME_RS10215
uniprot id: W0EE08
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

871968:DESME RS09495
gene id: 871968:DESME_RS09495
uniprot id: W0ECS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

871968:DESME RS14585
gene id: 871968:DESME_RS14585
uniprot id: W0EBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

871968:DESME RS15955
gene id: 871968:DESME_RS15955
uniprot id: W0EGV4
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

871968:DESME RS04365
gene id: 871968:DESME_RS04365
uniprot id: W0EBH2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

871968:DESME RS04155
gene id: 871968:DESME_RS04155
uniprot id: W0E684
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

871968:DESME RS11735
gene id: 871968:DESME_RS11735
uniprot id: W0EF73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

871968:DESME RS01320
gene id: 871968:DESME_RS01320
uniprot id: W0E8N5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

871968:DESME RS10820
gene id: 871968:DESME_RS10820
uniprot id: W0E9H1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS02590
gene id: 871968:DESME_RS02590
uniprot id: W0EA35
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

871968:DESME RS12865
gene id: 871968:DESME_RS12865
uniprot id: W0EFR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

871968:DESME RS01255
gene id: 871968:DESME_RS01255
uniprot id: W0E9Y8
names: Similarity
messages: Belongs to the ycf81 family.

871968:DESME RS15205
gene id: 871968:DESME_RS15205
uniprot id: W0EGL5
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

871968:DESME RS09025
gene id: 871968:DESME_RS09025
uniprot id: W0E8R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

871968:DESME RS01525
gene id: 871968:DESME_RS01525
uniprot id: W0E9M1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

871968:DESME RS07295
gene id: 871968:DESME_RS07295
uniprot id: W0E861
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

871968:DESME RS02225
gene id: 871968:DESME_RS02225
uniprot id: W0E9X3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

871968:DESME RS06800
gene id: 871968:DESME_RS06800
uniprot id: W0E7W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

871968:DESME RS06865
gene id: 871968:DESME_RS06865
uniprot id: W0E7N4
names: Similarity
messages: Belongs to the peptidase A24 family.

871968:DESME RS06020
gene id: 871968:DESME_RS06020
uniprot id: W0EB24
names: Similarity
messages: Belongs to the peptidase C40 family.

871968:DESME RS14475
gene id: 871968:DESME_RS14475
uniprot id: W0EG93
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS03160
gene id: 871968:DESME_RS03160
uniprot id: W0E639
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

871968:DESME RS14710
gene id: 871968:DESME_RS14710
uniprot id: W0EBL8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

871968:DESME RS13205
gene id: 871968:DESME_RS13205
uniprot id: W0EAS6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS14395
gene id: 871968:DESME_RS14395
uniprot id: W0EFC0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS08920
gene id: 871968:DESME_RS08920
uniprot id: W0EDT0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

871968:DESME RS09120
gene id: 871968:DESME_RS09120
uniprot id: W0E8T1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS00905
gene id: 871968:DESME_RS00905
uniprot id: W0E4Z2
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

871968:DESME RS12200
gene id: 871968:DESME_RS12200
uniprot id: W0EFF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

871968:DESME RS14365
gene id: 871968:DESME_RS14365
uniprot id: W0EG81
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

871968:DESME RS08785
gene id: 871968:DESME_RS08785
uniprot id: W0EDR2
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

871968:DESME RS06725
gene id: 871968:DESME_RS06725
uniprot id: G6GH15
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

871968:DESME RS07615
gene id: 871968:DESME_RS07615
uniprot id: W0E817
names: Similarity
messages: Belongs to the universal stress protein A family.

871968:DESME RS01955
gene id: 871968:DESME_RS01955
uniprot id: W0E9U1
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

871968:DESME RS11615
gene id: 871968:DESME_RS11615
uniprot id: W0EAB6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

871968:DESME RS12860
gene id: 871968:DESME_RS12860
uniprot id: W0EAL6
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS05915
gene id: 871968:DESME_RS05915
uniprot id: W0EB06
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

871968:DESME RS09950
gene id: 871968:DESME_RS09950
uniprot id: W0EE97
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

871968:DESME RS13260
gene id: 871968:DESME_RS13260
uniprot id: W0EAT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

871968:DESME RS09590
gene id: 871968:DESME_RS09590
uniprot id: W0E8Y5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS11115
gene id: 871968:DESME_RS11115
uniprot id: W0EEE7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS15320
gene id: 871968:DESME_RS15320
uniprot id: W0EBC7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

871968:DESME RS01625
gene id: 871968:DESME_RS01625
uniprot id: W0EA49
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

871968:DESME RS13785
gene id: 871968:DESME_RS13785
uniprot id: W0EB35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

871968:DESME RS11075
gene id: 871968:DESME_RS11075
uniprot id: W0E9Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

871968:DESME RS10950
gene id: 871968:DESME_RS10950
uniprot id: W0E9W1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

871968:DESME RS00425
gene id: 871968:DESME_RS00425
uniprot id: W0E4T0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

871968:DESME RS00420
gene id: 871968:DESME_RS00420
uniprot id: W0E9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

871968:DESME RS10700
gene id: 871968:DESME_RS10700
uniprot id: W0EEJ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS12175
gene id: 871968:DESME_RS12175
uniprot id: W0EFE7
names: Subcellular Location Annotation
messages: Cytoplasm

871968:DESME RS12470
gene id: 871968:DESME_RS12470
uniprot id: W0EFJ1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

871968:DESME RS07850
gene id: 871968:DESME_RS07850
uniprot id: W0E859
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

871968:DESME RS13060
gene id: 871968:DESME_RS13060
uniprot id: W0EAQ4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

871968:DESME RS14905
gene id: 871968:DESME_RS14905
uniprot id: W0EC01
names: Similarity
messages: Belongs to the LacAB/RpiB family.

871968:DESME RS11050
gene id: 871968:DESME_RS11050
uniprot id: W0E9Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

871968:DESME RS00100
gene id: 871968:DESME_RS00100
uniprot id: W0E9G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

871968:DESME RS11100
gene id: 871968:DESME_RS11100
uniprot id: W0EHU2
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS01500
gene id: 871968:DESME_RS01500
uniprot id: W0E9L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

871968:DESME RS13825
gene id: 871968:DESME_RS13825
uniprot id: W0EBE3
names: Similarity
messages: Belongs to the peptidase S8 family.

871968:DESME RS12525
gene id: 871968:DESME_RS12525
uniprot id: W0EAR6
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

871968:DESME RS09490
gene id: 871968:DESME_RS09490
uniprot id: W0E982
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

871968:DESME RS11355
gene id: 871968:DESME_RS11355
uniprot id: W0EEX6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

871968:DESME RS04200
gene id: 871968:DESME_RS04200
uniprot id: W0EBE8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

871968:DESME RS04390
gene id: 871968:DESME_RS04390
uniprot id: W0EBH7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

871968:DESME RS01760
gene id: 871968:DESME_RS01760
uniprot id: W0E517
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

871968:DESME RS14070
gene id: 871968:DESME_RS14070
uniprot id: W0EFZ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

871968:DESME RS01710
gene id: 871968:DESME_RS01710
uniprot id: W0E5B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

871968:DESME RS11445
gene id: 871968:DESME_RS11445
uniprot id: W0EEK8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

871968:DESME RS14985
gene id: 871968:DESME_RS14985
uniprot id: W0EFL8
names: Similarity
messages: Belongs to the RpoE family.

871968:DESME RS04730
gene id: 871968:DESME_RS04730
uniprot id: W0E6H4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

871968:DESME RS08335
gene id: 871968:DESME_RS08335
uniprot id: W0EC92
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

871968:DESME RS15020
gene id: 871968:DESME_RS15020
uniprot id: W0EGI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

871968:DESME RS10880
gene id: 871968:DESME_RS10880
uniprot id: W0E9U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

871968:DESME RS14075
gene id: 871968:DESME_RS14075
uniprot id: W0EGE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

871968:DESME RS08820
gene id: 871968:DESME_RS08820
uniprot id: W0E8X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

871968:DESME RS00275
gene id: 871968:DESME_RS00275
uniprot id: W0E9J6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

871968:DESME RS07565
gene id: 871968:DESME_RS07565
uniprot id: W0E803
names: Similarity
messages: Belongs to the leucine-binding protein family.

871968:DESME RS10805
gene id: 871968:DESME_RS10805
uniprot id: W0E9T2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

871968:DESME RS08285
gene id: 871968:DESME_RS08285
uniprot id: W0E8E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

871968:DESME RS10955
gene id: 871968:DESME_RS10955
uniprot id: W0EDD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

871968:DESME RS11275
gene id: 871968:DESME_RS11275
uniprot id: W0E9R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

871968:DESME RS00405
gene id: 871968:DESME_RS00405
uniprot id: W0E8B3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

871968:DESME RS03045
gene id: 871968:DESME_RS03045
uniprot id: W0E5Q7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

871968:DESME RS01595
gene id: 871968:DESME_RS01595
uniprot id: W0E591
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS07805
gene id: 871968:DESME_RS07805
uniprot id: W0ED87
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

871968:DESME RS14685
gene id: 871968:DESME_RS14685
uniprot id: W0EBL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

871968:DESME RS03475
gene id: 871968:DESME_RS03475
uniprot id: W0E9R6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS00645
gene id: 871968:DESME_RS00645
uniprot id: W0E4K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

871968:DESME RS14950
gene id: 871968:DESME_RS14950
uniprot id: W0EGV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

871968:DESME RS04110
gene id: 871968:DESME_RS04110
uniprot id: W0E6J2
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

871968:DESME RS14840
gene id: 871968:DESME_RS14840
uniprot id: W0EGF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

871968:DESME RS01225
gene id: 871968:DESME_RS01225
uniprot id: W0E4S8
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

871968:DESME RS00005
gene id: 871968:DESME_RS00005
uniprot id: W0E4L7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

871968:DESME RS15170
gene id: 871968:DESME_RS15170
uniprot id: W0EC52
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS13010
gene id: 871968:DESME_RS13010
uniprot id: W0EAP5
names: Similarity
messages: Belongs to the glutamate synthase family.

871968:DESME RS00845
gene id: 871968:DESME_RS00845
uniprot id: W0E9C0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS05625
gene id: 871968:DESME_RS05625
uniprot id: W0EAS7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS14955
gene id: 871968:DESME_RS14955
uniprot id: W0EC12
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

871968:DESME RS01495
gene id: 871968:DESME_RS01495
uniprot id: W0E8S0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

871968:DESME RS03850
gene id: 871968:DESME_RS03850
uniprot id: W0E634
names: Similarity
messages: Belongs to the glutamine synthetase family.

871968:DESME RS07300
gene id: 871968:DESME_RS07300
uniprot id: W0EBP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

871968:DESME RS00620
gene id: 871968:DESME_RS00620
uniprot id: W0E4K2
names: Similarity
messages: Belongs to the phosphopentomutase family.

871968:DESME RS07525
gene id: 871968:DESME_RS07525
uniprot id: W0ECP6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

871968:DESME RS08980
gene id: 871968:DESME_RS08980
uniprot id: W0EDT8
names: Similarity
messages: Belongs to the peptidase S11 family.

871968:DESME RS14775
gene id: 871968:DESME_RS14775
uniprot id: W0EBX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

871968:DESME RS11375
gene id: 871968:DESME_RS11375
uniprot id: W0E9T9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

871968:DESME RS04060
gene id: 871968:DESME_RS04060
uniprot id: W0E6I6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

871968:DESME RS10995
gene id: 871968:DESME_RS10995
uniprot id: W0EEQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

871968:DESME RS13495
gene id: 871968:DESME_RS13495
uniprot id: W0EG26
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS09980
gene id: 871968:DESME_RS09980
uniprot id: W0E9G0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

871968:DESME RS06130
gene id: 871968:DESME_RS06130
uniprot id: W0EG68
names: Similarity
messages: Belongs to the peptidase M29 family.

871968:DESME RS05590
gene id: 871968:DESME_RS05590
uniprot id: W0E6W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

871968:DESME RS15200
gene id: 871968:DESME_RS15200
uniprot id: W0EFQ2
names: Similarity
messages: Belongs to the leucine-binding protein family.

871968:DESME RS13965
gene id: 871968:DESME_RS13965
uniprot id: W0EF10
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS09835
gene id: 871968:DESME_RS09835
uniprot id: W0EE78
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

871968:DESME RS08230
gene id: 871968:DESME_RS08230
uniprot id: W0EC70
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

871968:DESME RS05190
gene id: 871968:DESME_RS05190
uniprot id: W0EBV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

871968:DESME RS09570
gene id: 871968:DESME_RS09570
uniprot id: W0EE34
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

871968:DESME RS13735
gene id: 871968:DESME_RS13735
uniprot id: W0EG72
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

871968:DESME RS01285
gene id: 871968:DESME_RS01285
uniprot id: W0E539
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

871968:DESME RS00570
gene id: 871968:DESME_RS00570
uniprot id: W0E4J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

871968:DESME RS12090
gene id: 871968:DESME_RS12090
uniprot id: W0EF09
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

871968:DESME RS08670
gene id: 871968:DESME_RS08670
uniprot id: W0ECF5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

871968:DESME RS02595
gene id: 871968:DESME_RS02595
uniprot id: W0E5F0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

871968:DESME RS10865
gene id: 871968:DESME_RS10865
uniprot id: W0EE93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

871968:DESME RS07140
gene id: 871968:DESME_RS07140
uniprot id: W0EBL1
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

871968:DESME RS03915
gene id: 871968:DESME_RS03915
uniprot id: W0E9Y9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS12145
gene id: 871968:DESME_RS12145
uniprot id: W0EA96
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS02630
gene id: 871968:DESME_RS02630
uniprot id: W0E5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

871968:DESME RS15160
gene id: 871968:DESME_RS15160
uniprot id: W0EBT7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

871968:DESME RS11780
gene id: 871968:DESME_RS11780
uniprot id: W0EA44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

871968:DESME RS03560
gene id: 871968:DESME_RS03560
uniprot id: W0EHB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

871968:DESME RS10715
gene id: 871968:DESME_RS10715
uniprot id: W0EE67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

871968:DESME RS11350
gene id: 871968:DESME_RS11350
uniprot id: W0E9T4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

871968:DESME RS03050
gene id: 871968:DESME_RS03050
uniprot id: W0EAW1
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS10775
gene id: 871968:DESME_RS10775
uniprot id: W0EEK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

871968:DESME RS09345
gene id: 871968:DESME_RS09345
uniprot id: W0ECP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

871968:DESME RS06425
gene id: 871968:DESME_RS06425
uniprot id: W0E7P7
names: Similarity
messages: Belongs to the helicase family. RAD3/XPD subfamily.

871968:DESME RS10890
gene id: 871968:DESME_RS10890
uniprot id: W0EE99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

871968:DESME RS11045
gene id: 871968:DESME_RS11045
uniprot id: W0EER2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

871968:DESME RS13055
gene id: 871968:DESME_RS13055
uniprot id: W0EFH1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

871968:DESME RS11905
gene id: 871968:DESME_RS11905
uniprot id: W0EEX2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

871968:DESME RS00245
gene id: 871968:DESME_RS00245
uniprot id: W0E4F4
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

871968:DESME RS14535
gene id: 871968:DESME_RS14535
uniprot id: W0EBJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

871968:DESME RS01855
gene id: 871968:DESME_RS01855
uniprot id: W0E8W7
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS01925
gene id: 871968:DESME_RS01925
uniprot id: W0E8X3
names: Subcellular Location Annotation
messages: Cytoplasm

871968:DESME RS06885
gene id: 871968:DESME_RS06885
uniprot id: W0ECD8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS07135
gene id: 871968:DESME_RS07135
uniprot id: W0E816
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

871968:DESME RS11680
gene id: 871968:DESME_RS11680
uniprot id: W0EA29
names: Similarity
messages: Belongs to the ComB family.

871968:DESME RS13405
gene id: 871968:DESME_RS13405
uniprot id: W0EAW5
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

871968:DESME RS12320
gene id: 871968:DESME_RS12320
uniprot id: W0EE77
names: Similarity
messages: Belongs to the FlgM family.

871968:DESME RS09315
gene id: 871968:DESME_RS09315
uniprot id: W0E950
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

871968:DESME RS04385
gene id: 871968:DESME_RS04385
uniprot id: W0E6B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

871968:DESME RS07710
gene id: 871968:DESME_RS07710
uniprot id: W0E8D3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

871968:DESME RS12285
gene id: 871968:DESME_RS12285
uniprot id: W0EFG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

871968:DESME RS14895
gene id: 871968:DESME_RS14895
uniprot id: W0EBP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

871968:DESME RS03765
gene id: 871968:DESME_RS03765
uniprot id: W0EAS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

871968:DESME RS13845
gene id: 871968:DESME_RS13845
uniprot id: W0EB46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

871968:DESME RS09785
gene id: 871968:DESME_RS09785
uniprot id: W0EE70
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS07590
gene id: 871968:DESME_RS07590
uniprot id: W0E812
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

871968:DESME RS15145
gene id: 871968:DESME_RS15145
uniprot id: W0EC47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

871968:DESME RS11845
gene id: 871968:DESME_RS11845
uniprot id: W0EAE8
names: Similarity
messages: Belongs to the transpeptidase family.

871968:DESME RS13365
gene id: 871968:DESME_RS13365
uniprot id: W0EB63
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

871968:DESME RS03365
gene id: 871968:DESME_RS03365
uniprot id: W0E670
names: Similarity
messages: Belongs to the UPF0166 family.

871968:DESME RS00285
gene id: 871968:DESME_RS00285
uniprot id: W0E889
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

871968:DESME RS05030
gene id: 871968:DESME_RS05030
uniprot id: W0E6L5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

871968:DESME RS10295
gene id: 871968:DESME_RS10295
uniprot id: W0EEF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

871968:DESME RS09375
gene id: 871968:DESME_RS09375
uniprot id: W0EDM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

871968:DESME RS04495
gene id: 871968:DESME_RS04495
uniprot id: W0EBJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

871968:DESME RS02945
gene id: 871968:DESME_RS02945
uniprot id: W0EAS9
names: Similarity
messages: Belongs to the LuxC family.

871968:DESME RS03090
gene id: 871968:DESME_RS03090
uniprot id: W0EAF6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

871968:DESME RS01105
gene id: 871968:DESME_RS01105
uniprot id: W0E8J6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

871968:DESME RS01660
gene id: 871968:DESME_RS01660
uniprot id: W0E501
names: Similarity
messages: Belongs to the peptidase M20A family.

871968:DESME RS12305
gene id: 871968:DESME_RS12305
uniprot id: W0EAB9
names: Similarity
messages: Belongs to the bacterial flagellin family.

871968:DESME RS03935
gene id: 871968:DESME_RS03935
uniprot id: W0E6G9
names: Similarity
messages: Belongs to the glutamate synthase family.

871968:DESME RS11430
gene id: 871968:DESME_RS11430
uniprot id: W0EEZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

871968:DESME RS01490
gene id: 871968:DESME_RS01490
uniprot id: W0E576
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

871968:DESME RS13190
gene id: 871968:DESME_RS13190
uniprot id: W0EB27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

871968:DESME RS06715
gene id: 871968:DESME_RS06715
uniprot id: W0ECA7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

871968:DESME RS05135
gene id: 871968:DESME_RS05135
uniprot id: W0EBG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

871968:DESME RS04300
gene id: 871968:DESME_RS04300
uniprot id: W0EA50
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

871968:DESME RS00875
gene id: 871968:DESME_RS00875
uniprot id: W0E9T5
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

871968:DESME RS14315
gene id: 871968:DESME_RS14315
uniprot id: W0EGK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

871968:DESME RS01190
gene id: 871968:DESME_RS01190
uniprot id: W0E9F7
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

871968:DESME RS05435
gene id: 871968:DESME_RS05435
uniprot id: W0E749
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

871968:DESME RS05520
gene id: 871968:DESME_RS05520
uniprot id: W0EBN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

871968:DESME RS07310
gene id: 871968:DESME_RS07310
uniprot id: W0E7W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

871968:DESME RS11975
gene id: 871968:DESME_RS11975
uniprot id: W0EE17
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS03575
gene id: 871968:DESME_RS03575
uniprot id: W0EB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

871968:DESME RS10240
gene id: 871968:DESME_RS10240
uniprot id: W0EE13
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

871968:DESME RS14330
gene id: 871968:DESME_RS14330
uniprot id: W0EG76
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS06965
gene id: 871968:DESME_RS06965
uniprot id: W0E7Q3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

871968:DESME RS05140
gene id: 871968:DESME_RS05140
uniprot id: W0E6N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

871968:DESME RS14785
gene id: 871968:DESME_RS14785
uniprot id: W0EGE5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS14155
gene id: 871968:DESME_RS14155
uniprot id: W0EBA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

871968:DESME RS12690
gene id: 871968:DESME_RS12690
uniprot id: W0EFM9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

871968:DESME RS12910
gene id: 871968:DESME_RS12910
uniprot id: W0EAM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

871968:DESME RS06565
gene id: 871968:DESME_RS06565
uniprot id: W0E7S0
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

871968:DESME RS01915
gene id: 871968:DESME_RS01915
uniprot id: W0EA94
names: Subcellular Location Annotation
messages: Cytoplasm

871968:DESME RS07810
gene id: 871968:DESME_RS07810
uniprot id: W0E8F2
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

871968:DESME RS02750
gene id: 871968:DESME_RS02750
uniprot id: W0EA70
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS10420
gene id: 871968:DESME_RS10420
uniprot id: W0EE50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

871968:DESME RS11290
gene id: 871968:DESME_RS11290
uniprot id: W0EDK9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

871968:DESME RS13025
gene id: 871968:DESME_RS13025
uniprot id: W0EEJ7
names: Similarity
messages: Belongs to the EamA transporter family.

871968:DESME RS07450
gene id: 871968:DESME_RS07450
uniprot id: W0E7Y9
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS13625
gene id: 871968:DESME_RS13625
uniprot id: W0EG48
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

871968:DESME RS09655
gene id: 871968:DESME_RS09655
uniprot id: W0ECU5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

871968:DESME RS11450
gene id: 871968:DESME_RS11450
uniprot id: W0E9V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

871968:DESME RS08010
gene id: 871968:DESME_RS08010
uniprot id: W0EDC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

871968:DESME RS10115
gene id: 871968:DESME_RS10115
uniprot id: W0E9I4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

871968:DESME RS14845
gene id: 871968:DESME_RS14845
uniprot id: W0EBN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

871968:DESME RS01470
gene id: 871968:DESME_RS01470
uniprot id: W0E8R6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

871968:DESME RS14795
gene id: 871968:DESME_RS14795
uniprot id: W0EGT1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

871968:DESME RS04270
gene id: 871968:DESME_RS04270
uniprot id: W0E6K8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

871968:DESME RS04100
gene id: 871968:DESME_RS04100
uniprot id: W0E675
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

871968:DESME RS14800
gene id: 871968:DESME_RS14800
uniprot id: W0EBY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS00900
gene id: 871968:DESME_RS00900
uniprot id: W0E9U0
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

871968:DESME RS11015
gene id: 871968:DESME_RS11015
uniprot id: W0E9L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

871968:DESME RS10330
gene id: 871968:DESME_RS10330
uniprot id: W0EE33
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

871968:DESME RS13805
gene id: 871968:DESME_RS13805
uniprot id: W0EFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

871968:DESME RS12240
gene id: 871968:DESME_RS12240
uniprot id: W0EF34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

871968:DESME RS12015
gene id: 871968:DESME_RS12015
uniprot id: W0EFB8
names: Similarity
messages: Belongs to the MecA family.

871968:DESME RS01365
gene id: 871968:DESME_RS01365
uniprot id: W0E553
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

871968:DESME RS09325
gene id: 871968:DESME_RS09325
uniprot id: W0EDL6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

871968:DESME RS13490
gene id: 871968:DESME_RS13490
uniprot id: W0EAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

871968:DESME RS10945
gene id: 871968:DESME_RS10945
uniprot id: W0EEP0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

871968:DESME RS10875
gene id: 871968:DESME_RS10875
uniprot id: W0EEM6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

871968:DESME RS03855
gene id: 871968:DESME_RS03855
uniprot id: W0EB95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

871968:DESME RS00890
gene id: 871968:DESME_RS00890
uniprot id: W0E9C4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

871968:DESME RS03155
gene id: 871968:DESME_RS03155
uniprot id: W0EAX4
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

871968:DESME RS06630
gene id: 871968:DESME_RS06630
uniprot id: W0EBC3
names: Similarity
messages: Belongs to the CvfB family.

871968:DESME RS06320
gene id: 871968:DESME_RS06320
uniprot id: W0ECI1
names: Similarity
messages: Belongs to the Fur family.

871968:DESME RS05155
gene id: 871968:DESME_RS05155
uniprot id: W0E710
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

871968:DESME RS08300
gene id: 871968:DESME_RS08300
uniprot id: W0E8Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

871968:DESME RS11790
gene id: 871968:DESME_RS11790
uniprot id: W0EAE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

871968:DESME RS11225
gene id: 871968:DESME_RS11225
uniprot id: W0E9Q7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS06700
gene id: 871968:DESME_RS06700
uniprot id: W0ECP3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

871968:DESME RS10835
gene id: 871968:DESME_RS10835
uniprot id: W0EDB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

871968:DESME RS09575
gene id: 871968:DESME_RS09575
uniprot id: W0E997
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

871968:DESME RS01175
gene id: 871968:DESME_RS01175
uniprot id: W0E9X6
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS05230
gene id: 871968:DESME_RS05230
uniprot id: W0EAK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

871968:DESME RS06440
gene id: 871968:DESME_RS06440
uniprot id: W0E7F9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

871968:DESME RS04290
gene id: 871968:DESME_RS04290
uniprot id: W0EBF8
names: Similarity
messages: Belongs to the GARS family.

871968:DESME RS03040
gene id: 871968:DESME_RS03040
uniprot id: W0EAE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

871968:DESME RS07420
gene id: 871968:DESME_RS07420
uniprot id: W0ECP9
names: Similarity
messages: Belongs to the RNase H family.

871968:DESME RS08130
gene id: 871968:DESME_RS08130
uniprot id: W0ED36
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS00265
gene id: 871968:DESME_RS00265
uniprot id: W0E935
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

871968:DESME RS12150
gene id: 871968:DESME_RS12150
uniprot id: W0EFE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

871968:DESME RS12050
gene id: 871968:DESME_RS12050
uniprot id: W0EAI5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

871968:DESME RS05495
gene id: 871968:DESME_RS05495
uniprot id: W0EBN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

871968:DESME RS05015
gene id: 871968:DESME_RS05015
uniprot id: W0E6Y7
names: Similarity
messages: Belongs to the peptidase M29 family.

871968:DESME RS14965
gene id: 871968:DESME_RS14965
uniprot id: W0EGH5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS08365
gene id: 871968:DESME_RS08365
uniprot id: W0ED98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

871968:DESME RS13790
gene id: 871968:DESME_RS13790
uniprot id: W0EG83
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

871968:DESME RS06530
gene id: 871968:DESME_RS06530
uniprot id: W0E7H1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

871968:DESME RS13080
gene id: 871968:DESME_RS13080
uniprot id: W0EFH6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS10920
gene id: 871968:DESME_RS10920
uniprot id: W0EEN5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

871968:DESME RS12735
gene id: 871968:DESME_RS12735
uniprot id: W0EAJ5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

871968:DESME RS07845
gene id: 871968:DESME_RS07845
uniprot id: W0ECX6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

871968:DESME RS08380
gene id: 871968:DESME_RS08380
uniprot id: W0E8V2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

871968:DESME RS09650
gene id: 871968:DESME_RS09650
uniprot id: W0E9B1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

871968:DESME RS14615
gene id: 871968:DESME_RS14615
uniprot id: W0EGP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

871968:DESME RS06890
gene id: 871968:DESME_RS06890
uniprot id: W0E7N9
names: Similarity
messages: Belongs to the GSP E family.

871968:DESME RS06270
gene id: 871968:DESME_RS06270
uniprot id: W0E7C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

871968:DESME RS12530
gene id: 871968:DESME_RS12530
uniprot id: W0EEA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

871968:DESME RS11510
gene id: 871968:DESME_RS11510
uniprot id: W0EA99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

871968:DESME RS12235
gene id: 871968:DESME_RS12235
uniprot id: W0EE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

871968:DESME RS13985
gene id: 871968:DESME_RS13985
uniprot id: W0EBH1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

871968:DESME RS08125
gene id: 871968:DESME_RS08125
uniprot id: W0EC51
names: Similarity
messages: Belongs to the EamA transporter family.

871968:DESME RS06590
gene id: 871968:DESME_RS06590
uniprot id: W0ECM6
names: Similarity
messages: Belongs to the ArsC family.

871968:DESME RS15155
gene id: 871968:DESME_RS15155
uniprot id: W0EGK9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

871968:DESME RS08220
gene id: 871968:DESME_RS08220
uniprot id: W0EDH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

871968:DESME RS11955
gene id: 871968:DESME_RS11955
uniprot id: W0EEY3
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

871968:DESME RS10235
gene id: 871968:DESME_RS10235
uniprot id: W0ED35
names: Similarity
messages: Belongs to the UPF0297 family.

871968:DESME RS03510
gene id: 871968:DESME_RS03510
uniprot id: W0E5Y6
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS07275
gene id: 871968:DESME_RS07275
uniprot id: W0EBN7
names: Similarity
messages: Belongs to the histone deacetylase family.

871968:DESME RS04295
gene id: 871968:DESME_RS04295
uniprot id: W0E6L2
names: Similarity
messages: Belongs to the manganese catalase family.

871968:DESME RS13070
gene id: 871968:DESME_RS13070
uniprot id: W0EB05
names: Similarity
messages: Belongs to the TrpC family.

871968:DESME RS03540
gene id: 871968:DESME_RS03540
uniprot id: W0EC59
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

871968:DESME RS05485
gene id: 871968:DESME_RS05485
uniprot id: W0E760
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

871968:DESME RS14530
gene id: 871968:DESME_RS14530
uniprot id: W0EG99
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

871968:DESME RS05025
gene id: 871968:DESME_RS05025
uniprot id: W0EBE1
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

871968:DESME RS12380
gene id: 871968:DESME_RS12380
uniprot id: W0EF55
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS11995
gene id: 871968:DESME_RS11995
uniprot id: W0EAH6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

871968:DESME RS12720
gene id: 871968:DESME_RS12720
uniprot id: W0EAU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

871968:DESME RS04440
gene id: 871968:DESME_RS04440
uniprot id: W0E6C8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

871968:DESME RS08910
gene id: 871968:DESME_RS08910
uniprot id: W0EDG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

871968:DESME RS12055
gene id: 871968:DESME_RS12055
uniprot id: W0EE32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

871968:DESME RS00785
gene id: 871968:DESME_RS00785
uniprot id: W0E4X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

871968:DESME RS12500
gene id: 871968:DESME_RS12500
uniprot id: W0EAR0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

871968:DESME RS13640
gene id: 871968:DESME_RS13640
uniprot id: W0EFR8
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS10370
gene id: 871968:DESME_RS10370
uniprot id: W0EE41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

871968:DESME RS09310
gene id: 871968:DESME_RS09310
uniprot id: W0EDY6
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

871968:DESME RS02645
gene id: 871968:DESME_RS02645
uniprot id: W0E5G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

871968:DESME RS13095
gene id: 871968:DESME_RS13095
uniprot id: W0EB11
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

871968:DESME RS12445
gene id: 871968:DESME_RS12445
uniprot id: W0ECT8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

871968:DESME RS14690
gene id: 871968:DESME_RS14690
uniprot id: W0EGR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

871968:DESME RS01235
gene id: 871968:DESME_RS01235
uniprot id: W0E534
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

871968:DESME RS05395
gene id: 871968:DESME_RS05395
uniprot id: W0EAN6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS02140
gene id: 871968:DESME_RS02140
uniprot id: W0E9W5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

871968:DESME RS01325
gene id: 871968:DESME_RS01325
uniprot id: W0E9H9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

871968:DESME RS15250
gene id: 871968:DESME_RS15250
uniprot id: W0EFR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

871968:DESME RS07095
gene id: 871968:DESME_RS07095
uniprot id: W0ECI0
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS10885
gene id: 871968:DESME_RS10885
uniprot id: W0EDC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

871968:DESME RS14625
gene id: 871968:DESME_RS14625
uniprot id: W0EFF4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

871968:DESME RS04335
gene id: 871968:DESME_RS04335
uniprot id: W0E6A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

871968:DESME RS12190
gene id: 871968:DESME_RS12190
uniprot id: W0EF26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

871968:DESME RS06125
gene id: 871968:DESME_RS06125
uniprot id: W0E7A5
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS11485
gene id: 871968:DESME_RS11485
uniprot id: W0EA79
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

871968:DESME RS00635
gene id: 871968:DESME_RS00635
uniprot id: W0E8E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

871968:DESME RS12195
gene id: 871968:DESME_RS12195
uniprot id: W0EAA4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

871968:DESME RS08995
gene id: 871968:DESME_RS08995
uniprot id: W0EDH4
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS06925
gene id: 871968:DESME_RS06925
uniprot id: W0E7Y4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

871968:DESME RS03525
gene id: 871968:DESME_RS03525
uniprot id: W0E9S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
messages: Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
messages: Cytoplasm

871968:DESME RS02610
gene id: 871968:DESME_RS02610
uniprot id: W0E995
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

871968:DESME RS10840
gene id: 871968:DESME_RS10840
uniprot id: W0EE88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

871968:DESME RS09030
gene id: 871968:DESME_RS09030
uniprot id: W0EDU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

871968:DESME RS09580
gene id: 871968:DESME_RS09580
uniprot id: W0ECT1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

871968:DESME RS01675
gene id: 871968:DESME_RS01675
uniprot id: W0E8T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

871968:DESME RS08050
gene id: 871968:DESME_RS08050
uniprot id: W0ED21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS03115
gene id: 871968:DESME_RS03115
uniprot id: W0EAG2
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

871968:DESME RS01100
gene id: 871968:DESME_RS01100
uniprot id: W0E513
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

871968:DESME RS00390
gene id: 871968:DESME_RS00390
uniprot id: W0E4I0
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

871968:DESME RS07855
gene id: 871968:DESME_RS07855
uniprot id: W0ED97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

871968:DESME RS05020
gene id: 871968:DESME_RS05020
uniprot id: W0EAH2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

871968:DESME RS12955
gene id: 871968:DESME_RS12955
uniprot id: W0EFF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

871968:DESME RS14085
gene id: 871968:DESME_RS14085
uniprot id: W0EBJ3
names: Similarity
messages: Belongs to the peptidase C40 family.

871968:DESME RS03825
gene id: 871968:DESME_RS03825
uniprot id: W0E630
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

871968:DESME RS04360
gene id: 871968:DESME_RS04360
uniprot id: W0E6B3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

871968:DESME RS08850
gene id: 871968:DESME_RS08850
uniprot id: W0ECH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

871968:DESME RS04065
gene id: 871968:DESME_RS04065
uniprot id: W0EA16
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

871968:DESME RS09105
gene id: 871968:DESME_RS09105
uniprot id: W0E926
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

871968:DESME RS11070
gene id: 871968:DESME_RS11070
uniprot id: W0EES0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

871968:DESME RS11055
gene id: 871968:DESME_RS11055
uniprot id: W0EDG3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

871968:DESME RS12590
gene id: 871968:DESME_RS12590
uniprot id: W0EFL1
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS01665
gene id: 871968:DESME_RS01665
uniprot id: W0EA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

871968:DESME RS05655
gene id: 871968:DESME_RS05655
uniprot id: W0EBR1
names: Similarity
messages: Belongs to the UPF0234 family.

871968:DESME RS07195
gene id: 871968:DESME_RS07195
uniprot id: W0EBM0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

871968:DESME RS05165
gene id: 871968:DESME_RS05165
uniprot id: W0EBH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

871968:DESME RS05785
gene id: 871968:DESME_RS05785
uniprot id: W0EBW2
names: Similarity
messages: Belongs to the peptidase S58 family.

871968:DESME RS10230
gene id: 871968:DESME_RS10230
uniprot id: W0E9J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

871968:DESME RS08160
gene id: 871968:DESME_RS08160
uniprot id: W0E8C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

871968:DESME RS04260
gene id: 871968:DESME_RS04260
uniprot id: W0E695
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

871968:DESME RS06770
gene id: 871968:DESME_RS06770
uniprot id: W0ECQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

871968:DESME RS06050
gene id: 871968:DESME_RS06050
uniprot id: W0E792
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS08035
gene id: 871968:DESME_RS08035
uniprot id: W0EDD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

871968:DESME RS04350
gene id: 871968:DESME_RS04350
uniprot id: W0EA58
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

871968:DESME RS07265
gene id: 871968:DESME_RS07265
uniprot id: W0ECZ7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

871968:DESME RS06335
gene id: 871968:DESME_RS06335
uniprot id: W0E7E0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

871968:DESME RS01360
gene id: 871968:DESME_RS01360
uniprot id: W0EA05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

871968:DESME RS11025
gene id: 871968:DESME_RS11025
uniprot id: W0E9X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

871968:DESME RS07555
gene id: 871968:DESME_RS07555
uniprot id: W0EBT0
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS10765
gene id: 871968:DESME_RS10765
uniprot id: W0EE76
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

871968:DESME RS03340
gene id: 871968:DESME_RS03340
uniprot id: W0EB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

871968:DESME RS11525
gene id: 871968:DESME_RS11525
uniprot id: W0E9Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS06620
gene id: 871968:DESME_RS06620
uniprot id: W0E7T2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

871968:DESME RS00820
gene id: 871968:DESME_RS00820
uniprot id: W0E9B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

871968:DESME RS11640
gene id: 871968:DESME_RS11640
uniprot id: W0EAB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

871968:DESME RS15265
gene id: 871968:DESME_RS15265
uniprot id: W0EH14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

871968:DESME RS04450
gene id: 871968:DESME_RS04450
uniprot id: W0E6N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

871968:DESME RS06910
gene id: 871968:DESME_RS06910
uniprot id: W0ECE3
names: Similarity
messages: Belongs to the peptidase M18 family.

871968:DESME RS03545
gene id: 871968:DESME_RS03545
uniprot id: W0EB42
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

871968:DESME RS10760
gene id: 871968:DESME_RS10760
uniprot id: W0EDA0
names: Similarity
messages: Belongs to the ribF family.

871968:DESME RS01745
gene id: 871968:DESME_RS01745
uniprot id: W0E5C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

871968:DESME RS11760
gene id: 871968:DESME_RS11760
uniprot id: W0EF77
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

871968:DESME RS08865
gene id: 871968:DESME_RS08865
uniprot id: W0EDS4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

871968:DESME RS10965
gene id: 871968:DESME_RS10965
uniprot id: W0E9K4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS01385
gene id: 871968:DESME_RS01385
uniprot id: W0EA10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

871968:DESME RS03750
gene id: 871968:DESME_RS03750
uniprot id: W0EB77
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

871968:DESME RS07980
gene id: 871968:DESME_RS07980
uniprot id: W0EDC4
names: Similarity
messages: Belongs to the UPF0178 family.

871968:DESME RS00410
gene id: 871968:DESME_RS00410
uniprot id: W0E962
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

871968:DESME RS00365
gene id: 871968:DESME_RS00365
uniprot id: W0E4H8
names: Similarity
messages: Belongs to the UPF0749 family.

871968:DESME RS05470
gene id: 871968:DESME_RS05470
uniprot id: W0EBM8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

871968:DESME RS09795
gene id: 871968:DESME_RS09795
uniprot id: W0ECX0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

871968:DESME RS03105
gene id: 871968:DESME_RS03105
uniprot id: W0E632
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

871968:DESME RS13065
gene id: 871968:DESME_RS13065
uniprot id: W0EFV0
names: Similarity
messages: Belongs to the peptidase S16 family.

871968:DESME RS11315
gene id: 871968:DESME_RS11315
uniprot id: W0EDL3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS11770
gene id: 871968:DESME_RS11770
uniprot id: W0EDY1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

871968:DESME RS03730
gene id: 871968:DESME_RS03730
uniprot id: W0E6D5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

871968:DESME RS15110
gene id: 871968:DESME_RS15110
uniprot id: W0EBS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

871968:DESME RS12265
gene id: 871968:DESME_RS12265
uniprot id: W0EF38
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

871968:DESME RS10080
gene id: 871968:DESME_RS10080
uniprot id: W0E976
names: Similarity
messages: Belongs to the GSP E family.

871968:DESME RS08690
gene id: 871968:DESME_RS08690
uniprot id: W0E8W9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS07050
gene id: 871968:DESME_RS07050
uniprot id: W0E7R7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS02900
gene id: 871968:DESME_RS02900
uniprot id: W0E5W1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

871968:DESME RS14665
gene id: 871968:DESME_RS14665
uniprot id: W0EGQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

871968:DESME RS05775
gene id: 871968:DESME_RS05775
uniprot id: W0EAY3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

871968:DESME RS11800
gene id: 871968:DESME_RS11800
uniprot id: W0EEV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS01510
gene id: 871968:DESME_RS01510
uniprot id: W0EA34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

871968:DESME RS12295
gene id: 871968:DESME_RS12295
uniprot id: W0EE73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

871968:DESME RS08870
gene id: 871968:DESME_RS08870
uniprot id: W0E8Y8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

871968:DESME RS04825
gene id: 871968:DESME_RS04825
uniprot id: W0EAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

871968:DESME RS05490
gene id: 871968:DESME_RS05490
uniprot id: W0EAQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS02695
gene id: 871968:DESME_RS02695
uniprot id: W0E5H4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

871968:DESME RS03720
gene id: 871968:DESME_RS03720
uniprot id: W0E612
names: Similarity
messages: Belongs to the CobH/CbiC family.

871968:DESME RS12475
gene id: 871968:DESME_RS12475
uniprot id: W0EAQ5
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

871968:DESME RS07920
gene id: 871968:DESME_RS07920
uniprot id: W0ECZ5
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS11460
gene id: 871968:DESME_RS11460
uniprot id: W0EA62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

871968:DESME RS11620
gene id: 871968:DESME_RS11620
uniprot id: W0EDV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

871968:DESME RS06610
gene id: 871968:DESME_RS06610
uniprot id: W0E7I4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS03370
gene id: 871968:DESME_RS03370
uniprot id: W0E9P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

871968:DESME RS08835
gene id: 871968:DESME_RS08835
uniprot id: W0E8N7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

871968:DESME RS01160
gene id: 871968:DESME_RS01160
uniprot id: W0E8K6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

871968:DESME RS08350
gene id: 871968:DESME_RS08350
uniprot id: W0EDL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

871968:DESME RS13385
gene id: 871968:DESME_RS13385
uniprot id: W0EG06
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

871968:DESME RS04220
gene id: 871968:DESME_RS04220
uniprot id: W0EGY8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

871968:DESME RS05970
gene id: 871968:DESME_RS05970
uniprot id: W0EB15
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

871968:DESME RS05600
gene id: 871968:DESME_RS05600
uniprot id: W0E780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

871968:DESME RS07935
gene id: 871968:DESME_RS07935
uniprot id: W0E8I4
names: Similarity
messages: Belongs to the DEAD box helicase family.

871968:DESME RS10195
gene id: 871968:DESME_RS10195
uniprot id: W0E989
names: Similarity
messages: Belongs to the GSP E family.

871968:DESME RS02540
gene id: 871968:DESME_RS02540
uniprot id: W0E977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

871968:DESME RS12420
gene id: 871968:DESME_RS12420
uniprot id: W0EE89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

871968:DESME RS07865
gene id: 871968:DESME_RS07865
uniprot id: W0EBZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

871968:DESME RS14935
gene id: 871968:DESME_RS14935
uniprot id: W0EFL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

871968:DESME RS03065
gene id: 871968:DESME_RS03065
uniprot id: W0EAF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

871968:DESME RS14855
gene id: 871968:DESME_RS14855
uniprot id: W0EBZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

871968:DESME RS05860
gene id: 871968:DESME_RS05860
uniprot id: W0EAZ8
names: Similarity
messages: Belongs to the RutC family.

871968:DESME RS14640
gene id: 871968:DESME_RS14640
uniprot id: W0EGQ1
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

871968:DESME RS14575
gene id: 871968:DESME_RS14575
uniprot id: W0EFE6
names: Similarity
messages: Belongs to the sigma-54 factor family.

871968:DESME RS04630
gene id: 871968:DESME_RS04630
uniprot id: W0E6R7
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

871968:DESME RS01405
gene id: 871968:DESME_RS01405
uniprot id: W0E4W2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

871968:DESME RS14980
gene id: 871968:DESME_RS14980
uniprot id: W0EC17
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS04455
gene id: 871968:DESME_RS04455
uniprot id: W0EA76
names: Similarity
messages: Belongs to the peptidase C40 family.

871968:DESME RS12990
gene id: 871968:DESME_RS12990
uniprot id: W0EFT3
names: Similarity
messages: Belongs to the UPF0111 family.

871968:DESME RS11250
gene id: 871968:DESME_RS11250
uniprot id: W0E9R3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

871968:DESME RS14040
gene id: 871968:DESME_RS14040
uniprot id: W0EF23
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

871968:DESME RS15025
gene id: 871968:DESME_RS15025
uniprot id: W0EBR7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

871968:DESME RS06245
gene id: 871968:DESME_RS06245
uniprot id: W0ECG6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

871968:DESME RS08295
gene id: 871968:DESME_RS08295
uniprot id: W0EDJ3
names: Similarity
messages: Belongs to the asparagine synthetase family.

871968:DESME RS04330
gene id: 871968:DESME_RS04330
uniprot id: W0EB07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

871968:DESME RS13450
gene id: 871968:DESME_RS13450
uniprot id: W0EFN7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

871968:DESME RS01420
gene id: 871968:DESME_RS01420
uniprot id: W0E8Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

871968:DESME RS15490
gene id: 871968:DESME_RS15490
uniprot id: W0EG05
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS03735
gene id: 871968:DESME_RS03735
uniprot id: W0E9W3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

871968:DESME RS07690
gene id: 871968:DESME_RS07690
uniprot id: W0EBV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

871968:DESME RS04595
gene id: 871968:DESME_RS04595
uniprot id: W0EBL2
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS00470
gene id: 871968:DESME_RS00470
uniprot id: W0E9M7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

871968:DESME RS15005
gene id: 871968:DESME_RS15005
uniprot id: W0EC23
names: Similarity
messages: Belongs to the SleB family.

871968:DESME RS11340
gene id: 871968:DESME_RS11340
uniprot id: W0EDL8
names: Function
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

871968:DESME RS08885
gene id: 871968:DESME_RS08885
uniprot id: W0E8P7
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS13780
gene id: 871968:DESME_RS13780
uniprot id: W0EFU5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

871968:DESME RS10345
gene id: 871968:DESME_RS10345
uniprot id: W0E9M4
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS11385
gene id: 871968:DESME_RS11385
uniprot id: W0EA45
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS13860
gene id: 871968:DESME_RS13860
uniprot id: W0EEZ8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

871968:DESME RS01380
gene id: 871968:DESME_RS01380
uniprot id: W0E4V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

871968:DESME RS10405
gene id: 871968:DESME_RS10405
uniprot id: W0EEH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

871968:DESME RS02990
gene id: 871968:DESME_RS02990
uniprot id: W0E5P1
names: Subunit
messages: Homodimer.

871968:DESME RS12715
gene id: 871968:DESME_RS12715
uniprot id: W0EFN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

871968:DESME RS08925
gene id: 871968:DESME_RS08925
uniprot id: W0E8Z7
names: Similarity
messages: Belongs to the asparaginase 1 family.

871968:DESME RS10910
gene id: 871968:DESME_RS10910
uniprot id: W0EDD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

871968:DESME RS12510
gene id: 871968:DESME_RS12510
uniprot id: W0EF71
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

871968:DESME RS11245
gene id: 871968:DESME_RS11245
uniprot id: W0EEG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

871968:DESME RS08340
gene id: 871968:DESME_RS08340
uniprot id: W0ED81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

871968:DESME RS11815
gene id: 871968:DESME_RS11815
uniprot id: W0EF84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS11280
gene id: 871968:DESME_RS11280
uniprot id: W0EEV8
names: Similarity
messages: Belongs to the fabD family.

871968:DESME RS08065
gene id: 871968:DESME_RS08065
uniprot id: W0EDE1
names: Similarity
messages: Belongs to the type IA topoisomerase family.

871968:DESME RS12930
gene id: 871968:DESME_RS12930
uniprot id: W0EFE8
names: Similarity
messages: Belongs to the transpeptidase family.

871968:DESME RS06535
gene id: 871968:DESME_RS06535
uniprot id: W0ECL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

871968:DESME RS06095
gene id: 871968:DESME_RS06095
uniprot id: W0EB37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

871968:DESME RS13145
gene id: 871968:DESME_RS13145
uniprot id: W0EFW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

871968:DESME RS12070
gene id: 871968:DESME_RS12070
uniprot id: W0EFC8
names: Similarity
messages: Belongs to the FlgD family.

871968:DESME RS04095
gene id: 871968:DESME_RS04095
uniprot id: W0EAX2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

871968:DESME RS11870
gene id: 871968:DESME_RS11870
uniprot id: W0EAF2
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS09630
gene id: 871968:DESME_RS09630
uniprot id: W0ECU0
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

871968:DESME RS01465
gene id: 871968:DESME_RS01465
uniprot id: W0E571
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

871968:DESME RS11670
gene id: 871968:DESME_RS11670
uniprot id: W0EDW3
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

871968:DESME RS10130
gene id: 871968:DESME_RS10130
uniprot id: W0E985
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS01435
gene id: 871968:DESME_RS01435
uniprot id: W0EA19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

871968:DESME RS00415
gene id: 871968:DESME_RS00415
uniprot id: W0E4I3
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

871968:DESME RS15130
gene id: 871968:DESME_RS15130
uniprot id: W0EGK5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

871968:DESME RS09075
gene id: 871968:DESME_RS09075
uniprot id: W0E922
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

871968:DESME RS07240
gene id: 871968:DESME_RS07240
uniprot id: W0ECL2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

871968:DESME RS07305
gene id: 871968:DESME_RS07305
uniprot id: W0ECM8
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

871968:DESME RS05185
gene id: 871968:DESME_RS05185
uniprot id: W0EC93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

871968:DESME RS00125
gene id: 871968:DESME_RS00125
uniprot id: W0E9H2
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

871968:DESME RS06650
gene id: 871968:DESME_RS06650
uniprot id: W0E7T7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

871968:DESME RS11035
gene id: 871968:DESME_RS11035
uniprot id: W0EED3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

871968:DESME RS06115
gene id: 871968:DESME_RS06115
uniprot id: W0EB39
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

871968:DESME RS09865
gene id: 871968:DESME_RS09865
uniprot id: W0E9E2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

871968:DESME RS03980
gene id: 871968:DESME_RS03980
uniprot id: W0EBB8
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

871968:DESME RS05715
gene id: 871968:DESME_RS05715
uniprot id: W0EC71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

871968:DESME RS01205
gene id: 871968:DESME_RS01205
uniprot id: W0E529
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

871968:DESME RS00035
gene id: 871968:DESME_RS00035
uniprot id: W0E847
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

871968:DESME RS07695
gene id: 871968:DESME_RS07695
uniprot id: W0ECU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

871968:DESME RS04860
gene id: 871968:DESME_RS04860
uniprot id: W0E6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

871968:DESME RS00930
gene id: 871968:DESME_RS00930
uniprot id: W0E9C7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

871968:DESME RS01445
gene id: 871968:DESME_RS01445
uniprot id: W0E8R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

871968:DESME RS11365
gene id: 871968:DESME_RS11365
uniprot id: W0EDM3
names: Similarity
messages: Belongs to the asp23 family.

871968:DESME RS09370
gene id: 871968:DESME_RS09370
uniprot id: W0ECQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

871968:DESME RS05925
gene id: 871968:DESME_RS05925
uniprot id: W0E768
names: Similarity
messages: Belongs to the IMPACT family.

871968:DESME RS02605
gene id: 871968:DESME_RS02605
uniprot id: W0E5R2
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS01450
gene id: 871968:DESME_RS01450
uniprot id: W0E9K5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

871968:DESME RS07290
gene id: 871968:DESME_RS07290
uniprot id: W0ED02
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

871968:DESME RS01335
gene id: 871968:DESME_RS01335
uniprot id: W0EA00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

871968:DESME RS01400
gene id: 871968:DESME_RS01400
uniprot id: W0E9J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

871968:DESME RS12160
gene id: 871968:DESME_RS12160
uniprot id: W0EE53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

871968:DESME RS04265
gene id: 871968:DESME_RS04265
uniprot id: W0EBF3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

871968:DESME RS06355
gene id: 871968:DESME_RS06355
uniprot id: W0EC53
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

871968:DESME RS09340
gene id: 871968:DESME_RS09340
uniprot id: W0E955
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS08235
gene id: 871968:DESME_RS08235
uniprot id: W0E5W1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

871968:DESME RS01835
gene id: 871968:DESME_RS01835
uniprot id: W0E9R9
names: Similarity
messages: Belongs to the EamA transporter family.

871968:DESME RS07175
gene id: 871968:DESME_RS07175
uniprot id: W0E7U1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

871968:DESME RS10810
gene id: 871968:DESME_RS10810
uniprot id: W0EDA9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

871968:DESME RS02760
gene id: 871968:DESME_RS02760
uniprot id: W0E5U5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

871968:DESME RS06675
gene id: 871968:DESME_RS06675
uniprot id: W0ECN9
names: Similarity
messages: Belongs to the peptidase M29 family.

871968:DESME RS07165
gene id: 871968:DESME_RS07165
uniprot id: W0EBL6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

871968:DESME RS02320
gene id: 871968:DESME_RS02320
uniprot id: W0E937
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

871968:DESME RS14035
gene id: 871968:DESME_RS14035
uniprot id: W0EBI0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

871968:DESME RS08420
gene id: 871968:DESME_RS08420
uniprot id: W0EDB7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

871968:DESME RS15125
gene id: 871968:DESME_RS15125
uniprot id: W0EFN8
names: Similarity
messages: Belongs to the peptidase S16 family.

871968:DESME RS12125
gene id: 871968:DESME_RS12125
uniprot id: W0EFD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

871968:DESME RS15090
gene id: 871968:DESME_RS15090
uniprot id: W0EFN4
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

871968:DESME RS05345
gene id: 871968:DESME_RS05345
uniprot id: W0E6R3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

871968:DESME RS00200
gene id: 871968:DESME_RS00200
uniprot id: W0E9I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

871968:DESME RS12065
gene id: 871968:DESME_RS12065
uniprot id: W0EA86
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

871968:DESME RS14830
gene id: 871968:DESME_RS14830
uniprot id: W0EBY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

871968:DESME RS06055
gene id: 871968:DESME_RS06055
uniprot id: W0ECD3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

871968:DESME RS08175
gene id: 871968:DESME_RS08175
uniprot id: W0EC61
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

871968:DESME RS10270
gene id: 871968:DESME_RS10270
uniprot id: W0EEE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

871968:DESME RS04705
gene id: 871968:DESME_RS04705
uniprot id: W0E6H1
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS12965
gene id: 871968:DESME_RS12965
uniprot id: W0EFS8
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS03360
gene id: 871968:DESME_RS03360
uniprot id: W0E5W0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

871968:DESME RS06000
gene id: 871968:DESME_RS06000
uniprot id: W0EBZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

871968:DESME RS00830
gene id: 871968:DESME_RS00830
uniprot id: W0E9T1
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

871968:DESME RS06765
gene id: 871968:DESME_RS06765
uniprot id: W0E7L5
names: Subcellular Location Annotation
messages: Membrane

871968:DESME RS14205
gene id: 871968:DESME_RS14205
uniprot id: W0EBD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

871968:DESME RS04645
gene id: 871968:DESME_RS04645
uniprot id: W0E6G2
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

871968:DESME RS12875
gene id: 871968:DESME_RS12875
uniprot id: W0EEG9
names: Similarity
messages: Belongs to the isochorismate synthase family.

871968:DESME RS12170
gene id: 871968:DESME_RS12170
uniprot id: W0EAA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

871968:DESME RS07780
gene id: 871968:DESME_RS07780
uniprot id: W0ED83
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

871968:DESME RS05420
gene id: 871968:DESME_RS05420
uniprot id: W0EBL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

871968:DESME RS12935
gene id: 871968:DESME_RS12935
uniprot id: W0EAN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane