869250:TOT 040000928
gene id: 869250:TOT_040000928
uniprot id: J4C934
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

869250:TOT 020000854
gene id: 869250:TOT_020000854
uniprot id: J4DPF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

869250:TOT 040000722
gene id: 869250:TOT_040000722
uniprot id: J7M4N8
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010000093
gene id: 869250:TOT_010000093
uniprot id: J7M4J1
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

869250:TOT 020000109
gene id: 869250:TOT_020000109
uniprot id: J4C7Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

869250:TOT 020000219
gene id: 869250:TOT_020000219
uniprot id: J4DP21
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

869250:TOT 030000622
gene id: 869250:TOT_030000622
uniprot id: J4D9G0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

869250:TOT 010000323
gene id: 869250:TOT_010000323
uniprot id: J4C2K6
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

869250:TOT 030000885
gene id: 869250:TOT_030000885
uniprot id: J4D8M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: apicoplast

869250:TOT 010000363
gene id: 869250:TOT_010000363
uniprot id: J4C2L4
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 020000706
gene id: 869250:TOT_020000706
uniprot id: J4D7Y6
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

869250:TOT 010001255
gene id: 869250:TOT_010001255
uniprot id: J4CC84
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 030000362
gene id: 869250:TOT_030000362
uniprot id: J4DPQ2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

869250:TOT 030000272
gene id: 869250:TOT_030000272
uniprot id: J4C3T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 31 family.
messages: Nucleus

869250:TOT 010000834
gene id: 869250:TOT_010000834
uniprot id: J4CCH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

869250:TOT 010000153
gene id: 869250:TOT_010000153
uniprot id: J7MGR5
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

869250:TOT 040000196
gene id: 869250:TOT_040000196
uniprot id: J4DA92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

869250:TOT 010000339
gene id: 869250:TOT_010000339
uniprot id: J4CC69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Nucleus

869250:TOT 030000514
gene id: 869250:TOT_030000514
uniprot id: J4C3Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

869250:TOT 020000304
gene id: 869250:TOT_020000304
uniprot id: J4CCV2
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

869250:TOT 040000187
gene id: 869250:TOT_040000187
uniprot id: J4C497
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 040000300
gene id: 869250:TOT_040000300
uniprot id: J4DAE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

869250:TOT 010000904
gene id: 869250:TOT_010000904
uniprot id: J4DNS1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

869250:TOT 010001085
gene id: 869250:TOT_010001085
uniprot id: J4C311
names: Similarity
messages: Belongs to the acylphosphatase family.

869250:TOT 010001272
gene id: 869250:TOT_010001272
uniprot id: J4D5N5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

869250:TOT 010000631
gene id: 869250:TOT_010000631
uniprot id: J4D5T8
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

869250:TOT 030000693
gene id: 869250:TOT_030000693
uniprot id: J4CDN1
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 010001029
gene id: 869250:TOT_010001029
uniprot id: J4DNU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

869250:TOT 020001022
gene id: 869250:TOT_020001022
uniprot id: J4CCQ1
names: Similarity
messages: Belongs to the DXR family.

869250:TOT 030000482
gene id: 869250:TOT_030000482
uniprot id: J4DPS6
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 040000310
gene id: 869250:TOT_040000310
uniprot id: J4DAE8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

869250:TOT 020000686
gene id: 869250:TOT_020000686
uniprot id: J4D7X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

869250:TOT 020001080
gene id: 869250:TOT_020001080
uniprot id: J4DPB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

869250:TOT 010000447
gene id: 869250:TOT_010000447
uniprot id: J4CC91
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

869250:TOT 040000301
gene id: 869250:TOT_040000301
uniprot id: J4C4C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

869250:TOT 010000710
gene id: 869250:TOT_010000710
uniprot id: J4C2T5
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

869250:TOT 020000351
gene id: 869250:TOT_020000351
uniprot id: J4C833
names: Similarity
messages: Belongs to the peptidase S16 family.

869250:TOT 020000314
gene id: 869250:TOT_020000314
uniprot id: J4CCV4
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

869250:TOT 040000373
gene id: 869250:TOT_040000373
uniprot id: J4C964
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

869250:TOT 020000812
gene id: 869250:TOT_020000812
uniprot id: J4CD56
names: Similarity
messages: Belongs to the heat shock protein 70 family.

869250:TOT 040000133
gene id: 869250:TOT_040000133
uniprot id: J4C486
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869250:TOT 040000050
gene id: 869250:TOT_040000050
uniprot id: J4DQ16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

869250:TOT 010000959
gene id: 869250:TOT_010000959
uniprot id: J4DNT2
names: Similarity
messages: Belongs to the actin family.

869250:TOT 010000030
gene id: 869250:TOT_010000030
uniprot id: J7MGK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

869250:TOT 020000431
gene id: 869250:TOT_020000431
uniprot id: J4DP65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

869250:TOT 010001278
gene id: 869250:TOT_010001278
uniprot id: J4D5S8
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

869250:TOT 030000154
gene id: 869250:TOT_030000154
uniprot id: J4C8J4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

869250:TOT 010001336
gene id: 869250:TOT_010001336
uniprot id: J4D6D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

869250:TOT 020000493
gene id: 869250:TOT_020000493
uniprot id: J4CCZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

869250:TOT 020000024
gene id: 869250:TOT_020000024
uniprot id: J4C335
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

869250:TOT 010000675
gene id: 869250:TOT_010000675
uniprot id: J4D5W6
names: Similarity
messages: Belongs to the NOP10 family.

869250:TOT 020000181
gene id: 869250:TOT_020000181
uniprot id: J4D721
names: Similarity
messages: Belongs to the type IB topoisomerase family.

869250:TOT 040000455
gene id: 869250:TOT_040000455
uniprot id: J4DQ98
names: Similarity
messages: Belongs to the lipin family.

869250:TOT 030000771
gene id: 869250:TOT_030000771
uniprot id: J4DPY4
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010000149
gene id: 869250:TOT_010000149
uniprot id: J7MBZ2
names: Subcellular Location Annotation
messages: Cytoplasm

869250:TOT 020000375
gene id: 869250:TOT_020000375
uniprot id: J4CCW7
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

869250:TOT 010001136
gene id: 869250:TOT_010001136
uniprot id: J4CCN1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

869250:TOT 040000461
gene id: 869250:TOT_040000461
uniprot id: J4DAM8
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 040000253
gene id: 869250:TOT_040000253
uniprot id: J4C940
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Belongs to the triosephosphate isomerase family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Homodimer.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

869250:TOT 040000521
gene id: 869250:TOT_040000521
uniprot id: J4C4G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

869250:TOT 030000371
gene id: 869250:TOT_030000371
uniprot id: J4C8N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

869250:TOT 030000616
gene id: 869250:TOT_030000616
uniprot id: J4DPV3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

869250:TOT 040000571
gene id: 869250:TOT_040000571
uniprot id: J4C4H6
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

869250:TOT 010001083
gene id: 869250:TOT_010001083
uniprot id: J4DNV7
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 030000270
gene id: 869250:TOT_030000270
uniprot id: J4DPN4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

869250:TOT 040000115
gene id: 869250:TOT_040000115
uniprot id: J4DQ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

869250:TOT 010000846
gene id: 869250:TOT_010000846
uniprot id: J4D675
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

869250:TOT 040000960
gene id: 869250:TOT_040000960
uniprot id: J4C4G0
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 010001099
gene id: 869250:TOT_010001099
uniprot id: J4D6L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homodimer.

869250:TOT 030000312
gene id: 869250:TOT_030000312
uniprot id: J4C3U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

869250:TOT 020000034
gene id: 869250:TOT_020000034
uniprot id: J4C7W8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

869250:TOT 040000890
gene id: 869250:TOT_040000890
uniprot id: J7MH40
names: Similarity
messages: Belongs to the MCM family.

869250:TOT 010000717
gene id: 869250:TOT_010000717
uniprot id: J4C7L7
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

869250:TOT 010000601
gene id: 869250:TOT_010000601
uniprot id: J4D5R9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

869250:TOT 020000944
gene id: 869250:TOT_020000944
uniprot id: J4D8B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

869250:TOT 020000584
gene id: 869250:TOT_020000584
uniprot id: J4D7S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Nucleus

869250:TOT 020001038
gene id: 869250:TOT_020001038
uniprot id: J4C378
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

869250:TOT 040000698
gene id: 869250:TOT_040000698
uniprot id: J7M4N2
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 030000363
gene id: 869250:TOT_030000363
uniprot id: J4D8Z5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

869250:TOT 030000911
gene id: 869250:TOT_030000911
uniprot id: J4DPP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

869250:TOT 030000582
gene id: 869250:TOT_030000582
uniprot id: J4DPU6
names: Similarity
messages: Belongs to the nuclease type I family.

869250:TOT 010000392
gene id: 869250:TOT_010000392
uniprot id: J4D5F3
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

869250:TOT 010001110
gene id: 869250:TOT_010001110
uniprot id: J4C316
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

869250:TOT 040000400
gene id: 869250:TOT_040000400
uniprot id: J4DQ87
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.

869250:TOT 020000088
gene id: 869250:TOT_020000088
uniprot id: J4CCQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

869250:TOT 010000800
gene id: 869250:TOT_010000800
uniprot id: J4CCG3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

869250:TOT 040000360
gene id: 869250:TOT_040000360
uniprot id: J4C4D2
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

869250:TOT 020000317
gene id: 869250:TOT_020000317
uniprot id: J4D798
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

869250:TOT 040000333
gene id: 869250:TOT_040000333
uniprot id: J4DQ73
names: Similarity
messages: Belongs to the peptidase C1 family.

869250:TOT 010000914
gene id: 869250:TOT_010000914
uniprot id: J4DNS3
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

869250:TOT 010000992
gene id: 869250:TOT_010000992
uniprot id: J4CCK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

869250:TOT 010001250
gene id: 869250:TOT_010001250
uniprot id: J4C7E8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

869250:TOT 020000122
gene id: 869250:TOT_020000122
uniprot id: J4C355
names: Similarity
messages: Belongs to the pyruvate kinase family.

869250:TOT 030000360
gene id: 869250:TOT_030000360
uniprot id: J4CDG4
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

869250:TOT 030000721
gene id: 869250:TOT_030000721
uniprot id: J4D9L4
names: Similarity
messages: Belongs to the universal ribosomal protein uL18 family.

869250:TOT 040000749
gene id: 869250:TOT_040000749
uniprot id: J7MCA1
names: Similarity
messages: Belongs to the AAA ATPase family.

869250:TOT 040000734
gene id: 869250:TOT_040000734
uniprot id: J7MC92
names: Similarity
messages: Belongs to the XPG/RAD2 endonuclease family.

869250:TOT 010001041
gene id: 869250:TOT_010001041
uniprot id: J4CCL2
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

869250:TOT 040000100
gene id: 869250:TOT_040000100
uniprot id: J4DQ26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.
messages: nucleolus

869250:TOT 030000340
gene id: 869250:TOT_030000340
uniprot id: J4DPP8
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

869250:TOT 020000227
gene id: 869250:TOT_020000227
uniprot id: J4D748
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

869250:TOT 030000838
gene id: 869250:TOT_030000838
uniprot id: J4D9S9
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 030000619
gene id: 869250:TOT_030000619
uniprot id: J4CDL6
names: Similarity
messages: Belongs to the SKP1 family.

869250:TOT 040000939
gene id: 869250:TOT_040000939
uniprot id: J4DQ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

869250:TOT 030000190
gene id: 869250:TOT_030000190
uniprot id: J4DPL8
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

869250:TOT 020001023
gene id: 869250:TOT_020001023
uniprot id: J4C354
names: Similarity
messages: Belongs to the DDI1 family.

869250:TOT 010000901
gene id: 869250:TOT_010000901
uniprot id: J4D6A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MET18/MMS19 family.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus

869250:TOT 040000429
gene id: 869250:TOT_040000429
uniprot id: J4C976
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

869250:TOT 040000473
gene id: 869250:TOT_040000473
uniprot id: J4CE14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

869250:TOT 020001008
gene id: 869250:TOT_020001008
uniprot id: J4C858
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

869250:TOT 030000237
gene id: 869250:TOT_030000237
uniprot id: J4C3T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the midasin family.
messages: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.
messages: Nucleus

869250:TOT 040000672
gene id: 869250:TOT_040000672
uniprot id: J4C9C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

869250:TOT 020001096
gene id: 869250:TOT_020001096
uniprot id: J4C3L2
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

869250:TOT 030000054
gene id: 869250:TOT_030000054
uniprot id: J4CDA3
names: Similarity
messages: Belongs to the DEAD box helicase family.

869250:TOT 010000440
gene id: 869250:TOT_010000440
uniprot id: J4D5H8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

869250:TOT 040000248
gene id: 869250:TOT_040000248
uniprot id: J4C939
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 040000500
gene id: 869250:TOT_040000500
uniprot id: J4DAQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

869250:TOT 030000426
gene id: 869250:TOT_030000426
uniprot id: J4C8P8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

869250:TOT 010001134
gene id: 869250:TOT_010001134
uniprot id: J4D6N1
names: Similarity
messages: Belongs to the TBCC family.

869250:TOT 040000254
gene id: 869250:TOT_040000254
uniprot id: J4DQ57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

869250:TOT 020000494
gene id: 869250:TOT_020000494
uniprot id: J4C862
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 040000058
gene id: 869250:TOT_040000058
uniprot id: J4CDT0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.

869250:TOT 030000809
gene id: 869250:TOT_030000809
uniprot id: J4C445
names: Similarity
messages: Belongs to the peptidase A1 family.

869250:TOT 040000061
gene id: 869250:TOT_040000061
uniprot id: J4D9Y9
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

869250:TOT 020000759
gene id: 869250:TOT_020000759
uniprot id: J4DPD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

869250:TOT 040000395
gene id: 869250:TOT_040000395
uniprot id: J4DQ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

869250:TOT 040000794
gene id: 869250:TOT_040000794
uniprot id: J7MCC6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

869250:TOT 010001256
gene id: 869250:TOT_010001256
uniprot id: J4C2M5
names: Similarity
messages: Belongs to the PITHD1 family.

869250:TOT 040000351
gene id: 869250:TOT_040000351
uniprot id: J4CDY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAP2/GCS1 family.
messages: Cell membrane
messages: Membrane

869250:TOT 020000865
gene id: 869250:TOT_020000865
uniprot id: J4D871
names: Similarity
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

869250:TOT 030000038
gene id: 869250:TOT_030000038
uniprot id: J4C3P0
names: Function
names: Similarity
messages: Belongs to the peptidase C13 family.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

869250:TOT 020000601
gene id: 869250:TOT_020000601
uniprot id: J4CD13
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

869250:TOT 040000420
gene id: 869250:TOT_040000420
uniprot id: J4DQ91
names: Similarity
messages: Belongs to the KRI1 family.

869250:TOT 030000579
gene id: 869250:TOT_030000579
uniprot id: J4C3Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

869250:TOT 030000857
gene id: 869250:TOT_030000857
uniprot id: J4DQ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

869250:TOT 010000035
gene id: 869250:TOT_010000035
uniprot id: J7MGK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

869250:TOT 020000547
gene id: 869250:TOT_020000547
uniprot id: J4CD02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

869250:TOT 030000324
gene id: 869250:TOT_030000324
uniprot id: J4C8M8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

869250:TOT 040000492
gene id: 869250:TOT_040000492
uniprot id: J4DQA6
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

869250:TOT 030000379
gene id: 869250:TOT_030000379
uniprot id: J4C3V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

869250:TOT 010001248
gene id: 869250:TOT_010001248
uniprot id: J4D5D6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

869250:TOT 030000182
gene id: 869250:TOT_030000182
uniprot id: J4C3R9
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010000353
gene id: 869250:TOT_010000353
uniprot id: J4C2L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

869250:TOT 030000196
gene id: 869250:TOT_030000196
uniprot id: J4D8Q9
names: Similarity
messages: Belongs to the peptidase A1 family.

869250:TOT 040000771
gene id: 869250:TOT_040000771
uniprot id: J7MF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Chromosome

869250:TOT 030000682
gene id: 869250:TOT_030000682
uniprot id: J4C420
names: Similarity
messages: Belongs to the NARF family.

869250:TOT 040000205
gene id: 869250:TOT_040000205
uniprot id: J4DA96
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

869250:TOT 010000496
gene id: 869250:TOT_010000496
uniprot id: J4C2P1
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

869250:TOT 030000325
gene id: 869250:TOT_030000325
uniprot id: J4DPP5
names: Similarity
messages: Belongs to the peptidase S14 family.

869250:TOT 040000210
gene id: 869250:TOT_040000210
uniprot id: J4DA98
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

869250:TOT 040000532
gene id: 869250:TOT_040000532
uniprot id: J4CE27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: apicoplast

869250:TOT 030000502
gene id: 869250:TOT_030000502
uniprot id: J4DPT0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

869250:TOT 020000066
gene id: 869250:TOT_020000066
uniprot id: J4D6V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

869250:TOT 030000442
gene id: 869250:TOT_030000442
uniprot id: J4DPR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

869250:TOT 010000389
gene id: 869250:TOT_010000389
uniprot id: J4CC79
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

869250:TOT 030000115
gene id: 869250:TOT_030000115
uniprot id: J4C8I6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

869250:TOT 020000286
gene id: 869250:TOT_020000286
uniprot id: J4DP35
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

869250:TOT 030000407
gene id: 869250:TOT_030000407
uniprot id: J4DPR1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

869250:TOT 030000512
gene id: 869250:TOT_030000512
uniprot id: J4DPT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

869250:TOT 020000480
gene id: 869250:TOT_020000480
uniprot id: J4DP75
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 040000244
gene id: 869250:TOT_040000244
uniprot id: J4DQ55
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

869250:TOT 010001344
gene id: 869250:TOT_010001344
uniprot id: J4C2Z3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 040000384
gene id: 869250:TOT_040000384
uniprot id: J4CDZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

869250:TOT 040000106
gene id: 869250:TOT_040000106
uniprot id: J4DA17
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

869250:TOT 020001094
gene id: 869250:TOT_020001094
uniprot id: J4CD66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

869250:TOT 040000916
gene id: 869250:TOT_040000916
uniprot id: J4DA08
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

869250:TOT 020000726
gene id: 869250:TOT_020000726
uniprot id: J4D7Z7
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

869250:TOT 020000084
gene id: 869250:TOT_020000084
uniprot id: J4C7X8
names: Similarity
messages: Belongs to the peptidase C1 family.

869250:TOT 030000569
gene id: 869250:TOT_030000569
uniprot id: J4C3Z7
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.

869250:TOT 020001068
gene id: 869250:TOT_020001068
uniprot id: J4C3E3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

869250:TOT 010000406
gene id: 869250:TOT_010000406
uniprot id: J4C2M3
names: Similarity
messages: Belongs to the acetyltransferase family. GCN5 subfamily.

869250:TOT 020000064
gene id: 869250:TOT_020000064
uniprot id: J4C7X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

869250:TOT 030000708
gene id: 869250:TOT_030000708
uniprot id: J4CDN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869250:TOT 010000691
gene id: 869250:TOT_010000691
uniprot id: J4C2T1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

869250:TOT 030000606
gene id: 869250:TOT_030000606
uniprot id: J4DPV1
names: Similarity
messages: Belongs to the formin-like family. Class-II subfamily.

869250:TOT 010000831
gene id: 869250:TOT_010000831
uniprot id: J4DNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

869250:TOT 040000057
gene id: 869250:TOT_040000057
uniprot id: J4C471
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

869250:TOT 040000290
gene id: 869250:TOT_040000290
uniprot id: J4DAD8
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 010001186
gene id: 869250:TOT_010001186
uniprot id: J4CCA1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

869250:TOT 020000316
gene id: 869250:TOT_020000316
uniprot id: J4DP41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

869250:TOT 010000475
gene id: 869250:TOT_010000475
uniprot id: J4D5J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

869250:TOT 040000305
gene id: 869250:TOT_040000305
uniprot id: J4DAE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

869250:TOT 040000139
gene id: 869250:TOT_040000139
uniprot id: J4CDU6
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010000217
gene id: 869250:TOT_010000217
uniprot id: J7MEV0
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

869250:TOT 040000110
gene id: 869250:TOT_040000110
uniprot id: J4DQ28
names: Similarity
messages: Belongs to the protein kinase superfamily.

869250:TOT 040000625
gene id: 869250:TOT_040000625
uniprot id: J4DAY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS11 family.
messages: chloroplast

869250:TOT 040000554
gene id: 869250:TOT_040000554
uniprot id: J4DQB9
names: Similarity
messages: Belongs to the peptidase S9A family.

869250:TOT 030000339
gene id: 869250:TOT_030000339
uniprot id: J4C8N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

869250:TOT 040000376
gene id: 869250:TOT_040000376
uniprot id: J4CDZ4
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 020000549
gene id: 869250:TOT_020000549
uniprot id: J4DP89
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 020001026
gene id: 869250:TOT_020001026
uniprot id: J4DP05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

869250:TOT 010000041
gene id: 869250:TOT_010000041
uniprot id: J7MBT2
names: Similarity
messages: Belongs to the hexokinase family.

869250:TOT 020000554
gene id: 869250:TOT_020000554
uniprot id: J4D7P6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

869250:TOT 010000750
gene id: 869250:TOT_010000750
uniprot id: J4C2U3
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

869250:TOT 040000558
gene id: 869250:TOT_040000558
uniprot id: J4C9A3
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

869250:TOT 040000146
gene id: 869250:TOT_040000146
uniprot id: J4DQ35
names: Similarity
messages: Belongs to the VPS26 family.

869250:TOT 020000598
gene id: 869250:TOT_020000598
uniprot id: J4DPA0
names: Similarity
messages: Belongs to the 14-3-3 family.

869250:TOT 040000448
gene id: 869250:TOT_040000448
uniprot id: J4CE09
names: Similarity
messages: Belongs to the RRM CWC2 family.

869250:TOT 040000773
gene id: 869250:TOT_040000773
uniprot id: J7MGZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

869250:TOT 030000544
gene id: 869250:TOT_030000544
uniprot id: J4C3Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: Regulates also the sphingolipid metabolism.

869250:TOT 010001193
gene id: 869250:TOT_010001193
uniprot id: J4C2U9
names: Similarity
messages: Belongs to the HTATSF1 family.

869250:TOT 020000566
gene id: 869250:TOT_020000566
uniprot id: J4CD06
names: Similarity
messages: Belongs to the guanylate kinase family.

869250:TOT 030000303
gene id: 869250:TOT_030000303
uniprot id: J4CDF3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

869250:TOT 030000441
gene id: 869250:TOT_030000441
uniprot id: J4C8Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

869250:TOT 010000564
gene id: 869250:TOT_010000564
uniprot id: J4CCB5
names: Similarity
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

869250:TOT 040000172
gene id: 869250:TOT_040000172
uniprot id: J4DA60
names: Similarity
messages: Belongs to the DCP1 family.

869250:TOT 020000450
gene id: 869250:TOT_020000450
uniprot id: J4C853
names: Similarity
messages: Belongs to the CNOT9 family.

869250:TOT 030000817
gene id: 869250:TOT_030000817
uniprot id: J4DPZ3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

869250:TOT 010000178
gene id: 869250:TOT_010000178
uniprot id: J7M4K8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

869250:TOT 030000587
gene id: 869250:TOT_030000587
uniprot id: J4DPU7
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 030000598
gene id: 869250:TOT_030000598
uniprot id: J4C403
names: Similarity
messages: Belongs to the MYBBP1A family.

869250:TOT 010000976
gene id: 869250:TOT_010000976
uniprot id: J4C2Y9
names: Similarity
messages: Belongs to the AAR2 family.

869250:TOT 020000574
gene id: 869250:TOT_020000574
uniprot id: J4D7S1
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Tetramer of two alpha and two beta subunits.

869250:TOT 030000567
gene id: 869250:TOT_030000567
uniprot id: J4DPU3
names: Similarity
messages: Belongs to the peptidase C1 family.

869250:TOT 020000956
gene id: 869250:TOT_020000956
uniprot id: J4CD85
names: Similarity
messages: Belongs to the peptidase T1A family.

869250:TOT 040000575
gene id: 869250:TOT_040000575
uniprot id: J4DAV5
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

869250:TOT 030000737
gene id: 869250:TOT_030000737
uniprot id: J4D9M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

869250:TOT 020001102
gene id: 869250:TOT_020001102
uniprot id: J4C3M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Cytoplasm

869250:TOT 020000248
gene id: 869250:TOT_020000248
uniprot id: J4C381
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

869250:TOT 020000028
gene id: 869250:TOT_020000028
uniprot id: J4CCP6
names: Similarity
messages: Belongs to the PPP phosphatase family.

869250:TOT 040000699
gene id: 869250:TOT_040000699
uniprot id: J7MGW1
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 020000082
gene id: 869250:TOT_020000082
uniprot id: J4C347
names: Similarity
messages: Belongs to the peptidase C1 family.

869250:TOT 020000475
gene id: 869250:TOT_020000475
uniprot id: J4DP74
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

869250:TOT 030000422
gene id: 869250:TOT_030000422
uniprot id: J4DPR4
names: Similarity
messages: Belongs to the activator 1 small subunits family.

869250:TOT 010001228
gene id: 869250:TOT_010001228
uniprot id: J7MGU7
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

869250:TOT 010001352
gene id: 869250:TOT_010001352
uniprot id: J4DNU7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

869250:TOT 020000211
gene id: 869250:TOT_020000211
uniprot id: J4D737
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010001285
gene id: 869250:TOT_010001285
uniprot id: J4C7K8
names: Similarity
messages: Belongs to the CDK5RAP3 family.

869250:TOT 040000980
gene id: 869250:TOT_040000980
uniprot id: J7MCB4
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

869250:TOT 030000634
gene id: 869250:TOT_030000634
uniprot id: J4CDL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Nucleus
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.

869250:TOT 010001289
gene id: 869250:TOT_010001289
uniprot id: J4CCE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

869250:TOT 040000087
gene id: 869250:TOT_040000087
uniprot id: J4C477
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

869250:TOT 040000703
gene id: 869250:TOT_040000703
uniprot id: J7M4N3
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 030000614
gene id: 869250:TOT_030000614
uniprot id: J4CDL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

869250:TOT 030000487
gene id: 869250:TOT_030000487
uniprot id: J4DPS7
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Homotrimer.

869250:TOT 010000685
gene id: 869250:TOT_010000685
uniprot id: J4D5X2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

869250:TOT 040000613
gene id: 869250:TOT_040000613
uniprot id: J4C9B4
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

869250:TOT 030000650
gene id: 869250:TOT_030000650
uniprot id: J4C8U3
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

869250:TOT 020000269
gene id: 869250:TOT_020000269
uniprot id: J4CCU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

869250:TOT 040000520
gene id: 869250:TOT_040000520
uniprot id: J4DAR6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

869250:TOT 020001061
gene id: 869250:TOT_020001061
uniprot id: J4C3C5
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

869250:TOT 030000277
gene id: 869250:TOT_030000277
uniprot id: J4C3T8
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

869250:TOT 030000032
gene id: 869250:TOT_030000032
uniprot id: J4D8G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

869250:TOT 030000778
gene id: 869250:TOT_030000778
uniprot id: J4C439
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

869250:TOT 010000828
gene id: 869250:TOT_010000828
uniprot id: J4C2V9
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

869250:TOT 010001355
gene id: 869250:TOT_010001355
uniprot id: J4DNV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

869250:TOT 030000436
gene id: 869250:TOT_030000436
uniprot id: J4C8Q0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 020000092
gene id: 869250:TOT_020000092
uniprot id: J4C349
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

869250:TOT 020000073
gene id: 869250:TOT_020000073
uniprot id: J4CCQ5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

869250:TOT 010001054
gene id: 869250:TOT_010001054
uniprot id: J4D6I9
names: Similarity
messages: Belongs to the RPAP2 family.

869250:TOT 040000513
gene id: 869250:TOT_040000513
uniprot id: J4C994
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

869250:TOT 020000103
gene id: 869250:TOT_020000103
uniprot id: J4CCR1
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 030000608
gene id: 869250:TOT_030000608
uniprot id: J4C405
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

869250:TOT 010000629
gene id: 869250:TOT_010000629
uniprot id: J4C7J9
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 040000869
gene id: 869250:TOT_040000869
uniprot id: J7MH31
names: Similarity
messages: Belongs to the TIP family.

869250:TOT 040000443
gene id: 869250:TOT_040000443
uniprot id: J4CE08
names: Similarity
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

869250:TOT 010001319
gene id: 869250:TOT_010001319
uniprot id: J4C7Q1
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.

869250:TOT 020000489
gene id: 869250:TOT_020000489
uniprot id: J4C861
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

869250:TOT 010000593
gene id: 869250:TOT_010000593
uniprot id: J4CCC1
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

869250:TOT 010001094
gene id: 869250:TOT_010001094
uniprot id: J4D6K7
names: Similarity
messages: Belongs to the peptidase M18 family.

869250:TOT 020000753
gene id: 869250:TOT_020000753
uniprot id: J4C8B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

869250:TOT 040000120
gene id: 869250:TOT_040000120
uniprot id: J4C913
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.

869250:TOT 020000158
gene id: 869250:TOT_020000158
uniprot id: J4C362
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

869250:TOT 040000937
gene id: 869250:TOT_040000937
uniprot id: J4C946
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

869250:TOT 030000193
gene id: 869250:TOT_030000193
uniprot id: J4CDD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

869250:TOT 040000027
gene id: 869250:TOT_040000027
uniprot id: J4C465
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Membrane

869250:TOT 040000236
gene id: 869250:TOT_040000236
uniprot id: J4C4A7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

869250:TOT 040000924
gene id: 869250:TOT_040000924
uniprot id: J4DQ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

869250:TOT 030000804
gene id: 869250:TOT_030000804
uniprot id: J4C444
names: Subcellular Location Annotation
messages: nucleolus

869250:TOT 010000257
gene id: 869250:TOT_010000257
uniprot id: J7MEX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

869250:TOT 010000988
gene id: 869250:TOT_010000988
uniprot id: J4C7S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

869250:TOT 040000838
gene id: 869250:TOT_040000838
uniprot id: J7MH19
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

869250:TOT 020000798
gene id: 869250:TOT_020000798
uniprot id: J4C8C4
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

869250:TOT 040000555
gene id: 869250:TOT_040000555
uniprot id: J4DAU1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

869250:TOT 030000561
gene id: 869250:TOT_030000561
uniprot id: J4C8S5
names: Similarity
messages: Belongs to the peptidase C1 family.

869250:TOT 020000042
gene id: 869250:TOT_020000042
uniprot id: J4C339
names: Similarity
messages: Belongs to the PPase family.

869250:TOT 010000059
gene id: 869250:TOT_010000059
uniprot id: J7MGL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Enzyme with a broad specificity.
messages: Membrane

869250:TOT 020000699
gene id: 869250:TOT_020000699
uniprot id: J4C8A4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

869250:TOT 040000188
gene id: 869250:TOT_040000188
uniprot id: J4CDV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

869250:TOT 020000044
gene id: 869250:TOT_020000044
uniprot id: J4C7X0
names: Similarity
messages: Belongs to the NUF2 family.

869250:TOT 010001018
gene id: 869250:TOT_010001018
uniprot id: J4C7S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit and an accessory subunit.

869250:TOT 040000239
gene id: 869250:TOT_040000239
uniprot id: J4DQ54
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

869250:TOT 010000283
gene id: 869250:TOT_010000283
uniprot id: J4D5A6
names: Subcellular Location Annotation
messages: Cytoplasm

869250:TOT 010000255
gene id: 869250:TOT_010000255
uniprot id: J7MC43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTP family.
messages: Cytoplasm

869250:TOT 020000630
gene id: 869250:TOT_020000630
uniprot id: J4C890
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

869250:TOT 030000107
gene id: 869250:TOT_030000107
uniprot id: J4D8L6
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 010000079
gene id: 869250:TOT_010000079
uniprot id: J7MGM6
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 030000546
gene id: 869250:TOT_030000546
uniprot id: J4C8S2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

869250:TOT 040000882
gene id: 869250:TOT_040000882
uniprot id: J7MF86
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

869250:TOT 010000619
gene id: 869250:TOT_010000619
uniprot id: J4C7J7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

869250:TOT 020000031
gene id: 869250:TOT_020000031
uniprot id: J4D6T1
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

869250:TOT 040000579
gene id: 869250:TOT_040000579
uniprot id: J4DQC4
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

869250:TOT 040000713
gene id: 869250:TOT_040000713
uniprot id: J7MGW7
names: Similarity
messages: Belongs to the cytidylyltransferase family.

869250:TOT 040000067
gene id: 869250:TOT_040000067
uniprot id: J4C473
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

869250:TOT 040000770
gene id: 869250:TOT_040000770
uniprot id: J7M8L6
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.

869250:TOT 010000632
gene id: 869250:TOT_010000632
uniprot id: J4C2R9
names: Similarity
messages: Belongs to the AAA ATPase family.

869250:TOT 010000947
gene id: 869250:TOT_010000947
uniprot id: J4CCJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

869250:TOT 040000663
gene id: 869250:TOT_040000663
uniprot id: J4DQE1
names: Similarity
messages: Belongs to the peptidase M67A family.

869250:TOT 030000468
gene id: 869250:TOT_030000468
uniprot id: J4D959
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

869250:TOT 040000161
gene id: 869250:TOT_040000161
uniprot id: J4DQ38
names: Similarity
messages: Belongs to the peptidase C19 family.

869250:TOT 020000747
gene id: 869250:TOT_020000747
uniprot id: J4CD43
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

869250:TOT 040000688
gene id: 869250:TOT_040000688
uniprot id: J7M4N0
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

869250:TOT 010001117
gene id: 869250:TOT_010001117
uniprot id: J4C7U8
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

869250:TOT 030000156
gene id: 869250:TOT_030000156
uniprot id: J4D8N9
names: Similarity
messages: Belongs to the Rab GDI family.

869250:TOT 010000284
gene id: 869250:TOT_010000284
uniprot id: J4C2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

869250:TOT 020000350
gene id: 869250:TOT_020000350
uniprot id: J4CCW2
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

869250:TOT 020000524
gene id: 869250:TOT_020000524
uniprot id: J4DP84
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010000096
gene id: 869250:TOT_010000096
uniprot id: J7M854
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

869250:TOT 010001257
gene id: 869250:TOT_010001257
uniprot id: J4CC85
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

869250:TOT 010000782
gene id: 869250:TOT_010000782
uniprot id: J4DNP6
names: Similarity
messages: Belongs to the BRX1 family.

869250:TOT 040000844
gene id: 869250:TOT_040000844
uniprot id: J7MCF4
names: Similarity
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Homodimer.

869250:TOT 020000709
gene id: 869250:TOT_020000709
uniprot id: J4C8A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

869250:TOT 020001009
gene id: 869250:TOT_020001009
uniprot id: J4C3D6
names: Similarity
messages: Belongs to the MCM family.

869250:TOT 010000731
gene id: 869250:TOT_010000731
uniprot id: J4CCE9
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010001313
gene id: 869250:TOT_010001313
uniprot id: J4C7P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

869250:TOT 020000949
gene id: 869250:TOT_020000949
uniprot id: J4D8B7
names: Similarity
messages: Belongs to the synaptobrevin family.

869250:TOT 010000655
gene id: 869250:TOT_010000655
uniprot id: J4D5V3
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.

869250:TOT 030000505
gene id: 869250:TOT_030000505
uniprot id: J4CDJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

869250:TOT 020000175
gene id: 869250:TOT_020000175
uniprot id: J4C7Z6
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

869250:TOT 010001053
gene id: 869250:TOT_010001053
uniprot id: J4DNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

869250:TOT 010000829
gene id: 869250:TOT_010000829
uniprot id: J4CCG9
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Tetramer of two alpha and two beta subunits.

869250:TOT 020000455
gene id: 869250:TOT_020000455
uniprot id: J4C854
names: Similarity
messages: Belongs to the type II topoisomerase family.

869250:TOT 010001079
gene id: 869250:TOT_010001079
uniprot id: J4D6K0
names: Similarity
messages: Belongs to the UFD1 family.

869250:TOT 010000473
gene id: 869250:TOT_010000473
uniprot id: J4C7G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

869250:TOT 020001015
gene id: 869250:TOT_020001015
uniprot id: J4DPF6
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

869250:TOT 020000515
gene id: 869250:TOT_020000515
uniprot id: J4DP82
names: Similarity
messages: Belongs to the UFD1 family.

869250:TOT 020000345
gene id: 869250:TOT_020000345
uniprot id: J4CCW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.
messages: Nucleus

869250:TOT 030000406
gene id: 869250:TOT_030000406
uniprot id: J4C8P4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

869250:TOT 020000786
gene id: 869250:TOT_020000786
uniprot id: J4C3J1
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

869250:TOT 010001241
gene id: 869250:TOT_010001241
uniprot id: J4C7D0
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

869250:TOT 020000974
gene id: 869250:TOT_020000974
uniprot id: J4DPH6
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

869250:TOT 010001152
gene id: 869250:TOT_010001152
uniprot id: J4C7V5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 010000943
gene id: 869250:TOT_010000943
uniprot id: J4C7R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

869250:TOT 020000029
gene id: 869250:TOT_020000029
uniprot id: J4C7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Nucleus

869250:TOT 040000951
gene id: 869250:TOT_040000951
uniprot id: J4DQ83
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

869250:TOT 030000934
gene id: 869250:TOT_030000934
uniprot id: J4D9E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

869250:TOT 020000979
gene id: 869250:TOT_020000979
uniprot id: J4DPH7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

869250:TOT 010000621
gene id: 869250:TOT_010000621
uniprot id: J4D5T1
names: Similarity
messages: Belongs to the MCM family.

869250:TOT 020000083
gene id: 869250:TOT_020000083
uniprot id: J4CCQ7
names: Similarity
messages: Belongs to the peptidase C1 family.

869250:TOT 030000501
gene id: 869250:TOT_030000501
uniprot id: J4C8R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

869250:TOT 020000704
gene id: 869250:TOT_020000704
uniprot id: J4C8A5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

869250:TOT 040000618
gene id: 869250:TOT_040000618
uniprot id: J4C9B5
names: Subcellular Location Annotation
messages: nucleolus

869250:TOT 010000177
gene id: 869250:TOT_010000177
uniprot id: J7MET0
names: Similarity
messages: Belongs to the GroES chaperonin family.

869250:TOT 010000582
gene id: 869250:TOT_010000582
uniprot id: J4D5Q6
names: Similarity
messages: Belongs to the adenylate kinase family.

869250:TOT 010000747
gene id: 869250:TOT_010000747
uniprot id: J4C7M3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869250:TOT 010000824
gene id: 869250:TOT_010000824
uniprot id: J4CCG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

869250:TOT 030000404
gene id: 869250:TOT_030000404
uniprot id: J4C3W4
names: Similarity
messages: Belongs to the TMCO4 family.

869250:TOT 030000727
gene id: 869250:TOT_030000727
uniprot id: J4D9L5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

869250:TOT 040000412
gene id: 869250:TOT_040000412
uniprot id: J4C4E3
names: Function
names: Similarity
messages: Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism.
messages: In the C-terminal section; belongs to the thymidylate synthase family.
messages: In the N-terminal section; belongs to the dihydrofolate reductase family.

869250:TOT 020000172
gene id: 869250:TOT_020000172
uniprot id: J4D717
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

869250:TOT 020000938
gene id: 869250:TOT_020000938
uniprot id: J4DPG9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

869250:TOT 020000387
gene id: 869250:TOT_020000387
uniprot id: J4DP56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

869250:TOT 040000789
gene id: 869250:TOT_040000789
uniprot id: J7MCC3
names: Similarity
messages: Belongs to the SPCS3 family.

869250:TOT 030000779
gene id: 869250:TOT_030000779
uniprot id: J4CDP8
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

869250:TOT 030000630
gene id: 869250:TOT_030000630
uniprot id: J4C8T9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

869250:TOT 030000332
gene id: 869250:TOT_030000332
uniprot id: J4C3U9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

869250:TOT 030000915
gene id: 869250:TOT_030000915
uniprot id: J4DPQ0
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020000495
gene id: 869250:TOT_020000495
uniprot id: J4DP78
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

869250:TOT 040000232
gene id: 869250:TOT_040000232
uniprot id: J4CDW5
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 010000142
gene id: 869250:TOT_010000142
uniprot id: J7M4K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

869250:TOT 010001342
gene id: 869250:TOT_010001342
uniprot id: J4D6E6
names: Similarity
messages: Belongs to the peptidase S14 family.

869250:TOT 010001304
gene id: 869250:TOT_010001304
uniprot id: J4C7P1
names: Similarity
messages: Belongs to the PNO1 family.

869250:TOT 010000342
gene id: 869250:TOT_010000342
uniprot id: J4D5D2
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

869250:TOT 040000522
gene id: 869250:TOT_040000522
uniprot id: J4CE25
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

869250:TOT 010000071
gene id: 869250:TOT_010000071
uniprot id: J7M839
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869250:TOT 040000577
gene id: 869250:TOT_040000577
uniprot id: J4CE36
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 040000619
gene id: 869250:TOT_040000619
uniprot id: J4DQD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

869250:TOT 010000052
gene id: 869250:TOT_010000052
uniprot id: J7MEI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

869250:TOT 010000344
gene id: 869250:TOT_010000344
uniprot id: J4CC70
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

869250:TOT 030000123
gene id: 869250:TOT_030000123
uniprot id: J4CDB7
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

869250:TOT 020000148
gene id: 869250:TOT_020000148
uniprot id: J4C360
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

869250:TOT 010001283
gene id: 869250:TOT_010001283
uniprot id: J4D5U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

869250:TOT 010000466
gene id: 869250:TOT_010000466
uniprot id: J4C2N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Nucleus

869250:TOT 030000310
gene id: 869250:TOT_030000310
uniprot id: J4DPP2
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

869250:TOT 010000682
gene id: 869250:TOT_010000682
uniprot id: J4CCD9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

869250:TOT 040000666
gene id: 869250:TOT_040000666
uniprot id: J4CE54
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010001141
gene id: 869250:TOT_010001141
uniprot id: J4CCN2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

869250:TOT 010000962
gene id: 869250:TOT_010000962
uniprot id: J4CCJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

869250:TOT 040000788
gene id: 869250:TOT_040000788
uniprot id: J7MGZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

869250:TOT 020000413
gene id: 869250:TOT_020000413
uniprot id: J4C3B5
names: Similarity
messages: Belongs to the NDK family.

869250:TOT 010000180
gene id: 869250:TOT_010000180
uniprot id: J7MC04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

869250:TOT 040000822
gene id: 869250:TOT_040000822
uniprot id: J7M4S0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

869250:TOT 030000261
gene id: 869250:TOT_030000261
uniprot id: J4D8T8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

869250:TOT 020000776
gene id: 869250:TOT_020000776
uniprot id: J4C3I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

869250:TOT 040000806
gene id: 869250:TOT_040000806
uniprot id: J7MF52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

869250:TOT 030000028
gene id: 869250:TOT_030000028
uniprot id: J4C3N8
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 040000527
gene id: 869250:TOT_040000527
uniprot id: J4CE26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: apicoplast

869250:TOT 010001234
gene id: 869250:TOT_010001234
uniprot id: J7MC52
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

869250:TOT 010001042
gene id: 869250:TOT_010001042
uniprot id: J4C7T3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

869250:TOT 030000686
gene id: 869250:TOT_030000686
uniprot id: J4D9J7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

869250:TOT 030000235
gene id: 869250:TOT_030000235
uniprot id: J4DPM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

869250:TOT 030000481
gene id: 869250:TOT_030000481
uniprot id: J4C8Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

869250:TOT 030000667
gene id: 869250:TOT_030000667
uniprot id: J4D9I5
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

869250:TOT 030000173
gene id: 869250:TOT_030000173
uniprot id: J4CDC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

869250:TOT 040000156
gene id: 869250:TOT_040000156
uniprot id: J4DQ37
names: Similarity
messages: Belongs to the WD repeat coronin family.

869250:TOT 010000989
gene id: 869250:TOT_010000989
uniprot id: J4DNT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

869250:TOT 010001365
gene id: 869250:TOT_010001365
uniprot id: J4D6N7
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

869250:TOT 010000236
gene id: 869250:TOT_010000236
uniprot id: J7MEW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

869250:TOT 030000393
gene id: 869250:TOT_030000393
uniprot id: J4D912
names: Similarity
messages: Belongs to the CHFR family.

869250:TOT 030000114
gene id: 869250:TOT_030000114
uniprot id: J4CDB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

869250:TOT 040000031
gene id: 869250:TOT_040000031
uniprot id: J4D9X1
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

869250:TOT 010000760
gene id: 869250:TOT_010000760
uniprot id: J4C2U5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

869250:TOT 040000356
gene id: 869250:TOT_040000356
uniprot id: J4CDZ0
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.

869250:TOT 040000194
gene id: 869250:TOT_040000194
uniprot id: J4C928
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

869250:TOT 010000480
gene id: 869250:TOT_010000480
uniprot id: J4D5K0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

869250:TOT 020000957
gene id: 869250:TOT_020000957
uniprot id: J4D8C0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

869250:TOT 020000600
gene id: 869250:TOT_020000600
uniprot id: J4C3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM136 family.
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

869250:TOT 040000348
gene id: 869250:TOT_040000348
uniprot id: J4DQ76
names: Similarity
messages: Belongs to the cyclin family.

869250:TOT 020000861
gene id: 869250:TOT_020000861
uniprot id: J4C3K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

869250:TOT 030000183
gene id: 869250:TOT_030000183
uniprot id: J4CDC9
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

869250:TOT 040000550
gene id: 869250:TOT_040000550
uniprot id: J4DAT8
names: Similarity
messages: Belongs to the TRAPPC13 family.

869250:TOT 040000449
gene id: 869250:TOT_040000449
uniprot id: J4C980
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

869250:TOT 010000326
gene id: 869250:TOT_010000326
uniprot id: J4DNF3
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

869250:TOT 030000578
gene id: 869250:TOT_030000578
uniprot id: J4D9D7
names: Subcellular Location Annotation
messages: Cell surface

869250:TOT 040000308
gene id: 869250:TOT_040000308
uniprot id: J4C951
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: cytoskeleton

869250:TOT 030000049
gene id: 869250:TOT_030000049
uniprot id: J4CDA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

869250:TOT 040000942
gene id: 869250:TOT_040000942
uniprot id: J4CDY1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

869250:TOT 040000720
gene id: 869250:TOT_040000720
uniprot id: J7M8J6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.

869250:TOT 030000392
gene id: 869250:TOT_030000392
uniprot id: J4DPQ8
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869250:TOT 020000291
gene id: 869250:TOT_020000291
uniprot id: J4DP36
names: Similarity
messages: Belongs to the GroES chaperonin family.

869250:TOT 010000191
gene id: 869250:TOT_010000191
uniprot id: J7M8C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

869250:TOT 010001312
gene id: 869250:TOT_010001312
uniprot id: J4D687
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

869250:TOT 030000425
gene id: 869250:TOT_030000425
uniprot id: J4CDH7
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

869250:TOT 040000738
gene id: 869250:TOT_040000738
uniprot id: J7MGX6
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

869250:TOT 010001135
gene id: 869250:TOT_010001135
uniprot id: J4C321
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

869250:TOT 030000060
gene id: 869250:TOT_030000060
uniprot id: J4C8H5
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 040000982
gene id: 869250:TOT_040000982
uniprot id: J7M8Q2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

869250:TOT 010000958
gene id: 869250:TOT_010000958
uniprot id: J4C7R6
names: Similarity
messages: Belongs to the TCF25 family.

869250:TOT 030000409
gene id: 869250:TOT_030000409
uniprot id: J4C3W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

869250:TOT 020000155
gene id: 869250:TOT_020000155
uniprot id: J4C7Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

869250:TOT 010001086
gene id: 869250:TOT_010001086
uniprot id: J4CCM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

869250:TOT 020000386
gene id: 869250:TOT_020000386
uniprot id: J4C840
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

869250:TOT 030000545
gene id: 869250:TOT_030000545
uniprot id: J4CDK1
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

869250:TOT 020001103
gene id: 869250:TOT_020001103
uniprot id: J4DPH2
names: Similarity
messages: Belongs to the peptidase T1A family.

869250:TOT 030000818
gene id: 869250:TOT_030000818
uniprot id: J4D9R7
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

869250:TOT 010000669
gene id: 869250:TOT_010000669
uniprot id: J4DNM3
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

869250:TOT 030000687
gene id: 869250:TOT_030000687
uniprot id: J4C421
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.
messages: Mitochondrion
messages: Nucleus

869250:TOT 030000085
gene id: 869250:TOT_030000085
uniprot id: J4C8I0
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

869250:TOT 040000081
gene id: 869250:TOT_040000081
uniprot id: J4DA01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

869250:TOT 010000297
gene id: 869250:TOT_010000297
uniprot id: J4DNE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

869250:TOT 030000408
gene id: 869250:TOT_030000408
uniprot id: J4D921
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

869250:TOT 040000542
gene id: 869250:TOT_040000542
uniprot id: J4CE29
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

869250:TOT 030000664
gene id: 869250:TOT_030000664
uniprot id: J4CDM5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

869250:TOT 020001028
gene id: 869250:TOT_020001028
uniprot id: J4CCS3
names: Similarity
messages: Belongs to the PHF5 family.

869250:TOT 030000812
gene id: 869250:TOT_030000812
uniprot id: J4DPZ2
names: Similarity
messages: Belongs to the PDCD5 family.

869250:TOT 030000732
gene id: 869250:TOT_030000732
uniprot id: J4D9L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Membrane

869250:TOT 040000552
gene id: 869250:TOT_040000552
uniprot id: J4CE31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Nucleus

869250:TOT 010000300
gene id: 869250:TOT_010000300
uniprot id: J4CC61
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 030000507
gene id: 869250:TOT_030000507
uniprot id: J4DPT1
names: Similarity
messages: Belongs to the GPI family.

869250:TOT 030000331
gene id: 869250:TOT_030000331
uniprot id: J4D8X7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

869250:TOT 030000274
gene id: 869250:TOT_030000274
uniprot id: J4C8L8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

869250:TOT 030000931
gene id: 869250:TOT_030000931
uniprot id: J4C8S8
names: Similarity
messages: Belongs to the frataxin family.

869250:TOT 020000373
gene id: 869250:TOT_020000373
uniprot id: J4D7D1
names: Similarity
messages: Belongs to the protein kinase superfamily.

869250:TOT 030000808
gene id: 869250:TOT_030000808
uniprot id: J4D9R2
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

869250:TOT 010000304
gene id: 869250:TOT_010000304
uniprot id: J4C2K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

869250:TOT 040000369
gene id: 869250:TOT_040000369
uniprot id: J4DAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus

869250:TOT 020000714
gene id: 869250:TOT_020000714
uniprot id: J4C8A7
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 040000865
gene id: 869250:TOT_040000865
uniprot id: J7MCG4
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

869250:TOT 040000425
gene id: 869250:TOT_040000425
uniprot id: J4DQ92
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010000723
gene id: 869250:TOT_010000723
uniprot id: J4DNN4
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010000698
gene id: 869250:TOT_010000698
uniprot id: J4C7L3
names: Similarity
messages: Belongs to the SAS10 family.

869250:TOT 010000541
gene id: 869250:TOT_010000541
uniprot id: J4DNJ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

869250:TOT 030000653
gene id: 869250:TOT_030000653
uniprot id: J4C414
names: Function
names: Similarity
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

869250:TOT 010001019
gene id: 869250:TOT_010001019
uniprot id: J4DNU4
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.

869250:TOT 030000464
gene id: 869250:TOT_030000464
uniprot id: J4C3X6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

869250:TOT 040000636
gene id: 869250:TOT_040000636
uniprot id: J4CE48
names: Similarity
messages: Belongs to the DEAD box helicase family.

869250:TOT 030000660
gene id: 869250:TOT_030000660
uniprot id: J4C8U5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL21 family.

869250:TOT 010001203
gene id: 869250:TOT_010001203
uniprot id: J7MBS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

869250:TOT 040000707
gene id: 869250:TOT_040000707
uniprot id: J7MF03
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

869250:TOT 010001239
gene id: 869250:TOT_010001239
uniprot id: J4D5A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

869250:TOT 020000966
gene id: 869250:TOT_020000966
uniprot id: J4CD87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

869250:TOT 010000432
gene id: 869250:TOT_010000432
uniprot id: J4CC88
names: Similarity
messages: Belongs to the RNR ribonuclease family.

869250:TOT 020000965
gene id: 869250:TOT_020000965
uniprot id: J4C3M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

869250:TOT 040000986
gene id: 869250:TOT_040000986
uniprot id: J7MH27
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Parasitic protozoa lack the de novo purine biosynthesis pathway and rely exclusively on the salvage pathway for their purine nucleotide requirements.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.
messages: Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

869250:TOT 020001092
gene id: 869250:TOT_020001092
uniprot id: J4DPD9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

869250:TOT 040000787
gene id: 869250:TOT_040000787
uniprot id: J7M4Q9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

869250:TOT 010001107
gene id: 869250:TOT_010001107
uniprot id: J4C7U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

869250:TOT 010000954
gene id: 869250:TOT_010000954
uniprot id: J4DNT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

869250:TOT 040000325
gene id: 869250:TOT_040000325
uniprot id: J4DQ71
names: Similarity
messages: Belongs to the pyruvate kinase family.

869250:TOT 010000729
gene id: 869250:TOT_010000729
uniprot id: J4D601
names: Subcellular Location Annotation
messages: nucleolus

869250:TOT 010000303
gene id: 869250:TOT_010000303
uniprot id: J4D5B4
names: Similarity
messages: Belongs to the NOB1 family.

869250:TOT 010000898
gene id: 869250:TOT_010000898
uniprot id: J4CCI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures.
messages: Nucleus

869250:TOT 040000973
gene id: 869250:TOT_040000973
uniprot id: J7MEY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

869250:TOT 020000588
gene id: 869250:TOT_020000588
uniprot id: J4DP98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

869250:TOT 030000492
gene id: 869250:TOT_030000492
uniprot id: J4DPS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

869250:TOT 030000388
gene id: 869250:TOT_030000388
uniprot id: J4D910
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

869250:TOT 010001270
gene id: 869250:TOT_010001270
uniprot id: J4CCA7
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010000618
gene id: 869250:TOT_010000618
uniprot id: J4CCC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS18 family.

869250:TOT 020000356
gene id: 869250:TOT_020000356
uniprot id: J4C834
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.

869250:TOT 030000411
gene id: 869250:TOT_030000411
uniprot id: J4C8P5
names: Similarity
messages: Belongs to the RuvB family.

869250:TOT 010000837
gene id: 869250:TOT_010000837
uniprot id: J4C2W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

869250:TOT 040000600
gene id: 869250:TOT_040000600
uniprot id: J4DAW8
names: Similarity
messages: Belongs to the CCDC124 family.

869250:TOT 020000693
gene id: 869250:TOT_020000693
uniprot id: J4CD32
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

869250:TOT 010001353
gene id: 869250:TOT_010001353
uniprot id: J4D6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

869250:TOT 040000489
gene id: 869250:TOT_040000489
uniprot id: J4C4F9
names: Similarity
messages: Belongs to the proteasome subunit S1 family.

869250:TOT 020001044
gene id: 869250:TOT_020001044
uniprot id: J4CCV6
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 040000655
gene id: 869250:TOT_040000655
uniprot id: J4C4J3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

869250:TOT 020000708
gene id: 869250:TOT_020000708
uniprot id: J4CD35
names: Similarity
messages: Belongs to the CAF1 family.

869250:TOT 040000033
gene id: 869250:TOT_040000033
uniprot id: J4CDS5
names: Similarity
messages: Belongs to the importin alpha family.

869250:TOT 010001065
gene id: 869250:TOT_010001065
uniprot id: J4C307
names: Similarity
messages: Belongs to the VPS16 family.

869250:TOT 020000298
gene id: 869250:TOT_020000298
uniprot id: J4C391
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

869250:TOT 020000098
gene id: 869250:TOT_020000098
uniprot id: J4CCR0
names: Similarity
messages: Belongs to the MCM family.

869250:TOT 010000852
gene id: 869250:TOT_010000852
uniprot id: J4C2W4
names: Subcellular Location Annotation
messages: Cell surface

869250:TOT 030000465
gene id: 869250:TOT_030000465
uniprot id: J4CDI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

869250:TOT 030000562
gene id: 869250:TOT_030000562
uniprot id: J4DPU2
names: Similarity
messages: Belongs to the peptidase C1 family.

869250:TOT 020000533
gene id: 869250:TOT_020000533
uniprot id: J4C870
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

869250:TOT 020000674
gene id: 869250:TOT_020000674
uniprot id: J4CD28
names: Similarity
messages: Belongs to the RRF family.

869250:TOT 010001286
gene id: 869250:TOT_010001286
uniprot id: J4CCE0
names: Similarity
messages: Belongs to the protein kinase superfamily.

869250:TOT 020000453
gene id: 869250:TOT_020000453
uniprot id: J4C3C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

869250:TOT 020000133
gene id: 869250:TOT_020000133
uniprot id: J4C357
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

869250:TOT 040000181
gene id: 869250:TOT_040000181
uniprot id: J4DA68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

869250:TOT 020001089
gene id: 869250:TOT_020001089
uniprot id: J4C8B8
names: Similarity
messages: Belongs to the FUN14 family.

869250:TOT 030000351
gene id: 869250:TOT_030000351
uniprot id: J4C8N3
names: Similarity
messages: Belongs to the GET4 family.

869250:TOT 030000250
gene id: 869250:TOT_030000250
uniprot id: J4DPN0
names: Subcellular Location Annotation
messages: nucleolus

869250:TOT 020000038
gene id: 869250:TOT_020000038
uniprot id: J4CCP8
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

869250:TOT 010000671
gene id: 869250:TOT_010000671
uniprot id: J4C2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF-assemblin family.
messages: cytoskeleton

869250:TOT 040000391
gene id: 869250:TOT_040000391
uniprot id: J4DAI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

869250:TOT 010000190
gene id: 869250:TOT_010000190
uniprot id: J7MC09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

869250:TOT 010000869
gene id: 869250:TOT_010000869
uniprot id: J4C7P8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

869250:TOT 010001227
gene id: 869250:TOT_010001227
uniprot id: J7MC36
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

869250:TOT 010001036
gene id: 869250:TOT_010001036
uniprot id: J4CCL1
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

869250:TOT 010001330
gene id: 869250:TOT_010001330
uniprot id: J4C2Y0
names: Similarity
messages: Belongs to the activator 1 small subunits family.

869250:TOT 040000035
gene id: 869250:TOT_040000035
uniprot id: J4DQ13
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

869250:TOT 040000062
gene id: 869250:TOT_040000062
uniprot id: J4C472
names: Similarity
messages: Belongs to the peptidase C48 family.

869250:TOT 010000404
gene id: 869250:TOT_010000404
uniprot id: J4DNG9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

869250:TOT 020000863
gene id: 869250:TOT_020000863
uniprot id: J4C8D7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.

869250:TOT 030000086
gene id: 869250:TOT_030000086
uniprot id: J4DPJ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

869250:TOT 020000558
gene id: 869250:TOT_020000558
uniprot id: J4DP91
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

869250:TOT 010001207
gene id: 869250:TOT_010001207
uniprot id: J7M4I7
names: Caution
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869250:TOT 020000312
gene id: 869250:TOT_020000312
uniprot id: J4D795
names: Similarity
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.

869250:TOT 030000733
gene id: 869250:TOT_030000733
uniprot id: J4C430
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

869250:TOT 030000328
gene id: 869250:TOT_030000328
uniprot id: J4CDF8
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 040000754
gene id: 869250:TOT_040000754
uniprot id: J7MCA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

869250:TOT 040000603
gene id: 869250:TOT_040000603
uniprot id: J4C9B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

869250:TOT 020000532
gene id: 869250:TOT_020000532
uniprot id: J4CCZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

869250:TOT 010000784
gene id: 869250:TOT_010000784
uniprot id: J4C2V0
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

869250:TOT 010000793
gene id: 869250:TOT_010000793
uniprot id: J4D648
names: Similarity
messages: Belongs to the AAA ATPase family.

869250:TOT 040000386
gene id: 869250:TOT_040000386
uniprot id: J4DQ84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

869250:TOT 020001041
gene id: 869250:TOT_020001041
uniprot id: J4C815
names: Similarity
messages: Belongs to the DEAD box helicase family.

869250:TOT 010000594
gene id: 869250:TOT_010000594
uniprot id: J4C7J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apicomplexan parasites AMA1 family.
messages: Membrane

869250:TOT 010000526
gene id: 869250:TOT_010000526
uniprot id: J4C7H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: nucleolus

869250:TOT 040000697
gene id: 869250:TOT_040000697
uniprot id: J7MEZ8
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 010000431
gene id: 869250:TOT_010000431
uniprot id: J4C2M8
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

869250:TOT 010001322
gene id: 869250:TOT_010001322
uniprot id: J4C7Q4
names: Similarity
messages: Belongs to the Tim44 family.

869250:TOT 020001043
gene id: 869250:TOT_020001043
uniprot id: J4C389
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

869250:TOT 040000163
gene id: 869250:TOT_040000163
uniprot id: J4C492
names: Similarity
messages: Belongs to the RMD1/sif2 family.

869250:TOT 020000687
gene id: 869250:TOT_020000687
uniprot id: J4C3H1
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 030000509
gene id: 869250:TOT_030000509
uniprot id: J4C3Y5
names: Similarity
messages: Belongs to the TSR2 family.

869250:TOT 030000335
gene id: 869250:TOT_030000335
uniprot id: J4DPP7
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 010001016
gene id: 869250:TOT_010001016
uniprot id: J4C2Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Component of the 60S subunit of the ribosome.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

869250:TOT 040000820
gene id: 869250:TOT_040000820
uniprot id: J7M8N8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

869250:TOT 010000333
gene id: 869250:TOT_010000333
uniprot id: J4C2K8
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

869250:TOT 030000247
gene id: 869250:TOT_030000247
uniprot id: J4C3T2
names: Similarity
messages: Belongs to the CMC family.
messages: Belongs to the EAF6 family.

869250:TOT 010000034
gene id: 869250:TOT_010000034
uniprot id: J7M4H9
names: Similarity
messages: Belongs to the EXO5 family.

869250:TOT 020000999
gene id: 869250:TOT_020000999
uniprot id: J4D742
names: Similarity
messages: Belongs to the NKAP family.

869250:TOT 010000106
gene id: 869250:TOT_010000106
uniprot id: J7M860
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

869250:TOT 040000711
gene id: 869250:TOT_040000711
uniprot id: J7M8J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF-assemblin family.
messages: cytoskeleton

869250:TOT 010000314
gene id: 869250:TOT_010000314
uniprot id: J4CC64
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.

869250:TOT 040000702
gene id: 869250:TOT_040000702
uniprot id: J7MF01
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 040000423
gene id: 869250:TOT_040000423
uniprot id: J4CE04
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

869250:TOT 010000338
gene id: 869250:TOT_010000338
uniprot id: J4C2K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

869250:TOT 010000993
gene id: 869250:TOT_010000993
uniprot id: J4C7S3
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

869250:TOT 010000252
gene id: 869250:TOT_010000252
uniprot id: J7MEW8
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

869250:TOT 010001237
gene id: 869250:TOT_010001237
uniprot id: J4D5A4
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

869250:TOT 010001224
gene id: 869250:TOT_010001224
uniprot id: J7MGT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

869250:TOT 010000578
gene id: 869250:TOT_010000578
uniprot id: J4C2Q8
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020001054
gene id: 869250:TOT_020001054
uniprot id: J4C835
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

869250:TOT 030000540
gene id: 869250:TOT_030000540
uniprot id: J4CDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Probable methyltransferase required to silence rDNA.
messages: nucleolus

869250:TOT 030000073
gene id: 869250:TOT_030000073
uniprot id: J4C3P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26B family.
messages: Endoplasmic reticulum membrane
messages: Membrane

869250:TOT 040000134
gene id: 869250:TOT_040000134
uniprot id: J4CDU5
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

869250:TOT 030000477
gene id: 869250:TOT_030000477
uniprot id: J4DPS5
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 040000166
gene id: 869250:TOT_040000166
uniprot id: J4DQ39
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

869250:TOT 020000296
gene id: 869250:TOT_020000296
uniprot id: J4DP37
names: Similarity
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.

869250:TOT 040000363
gene id: 869250:TOT_040000363
uniprot id: J4DQ79
names: Similarity
messages: Belongs to the DEAD box helicase family.

869250:TOT 010000094
gene id: 869250:TOT_010000094
uniprot id: J7MGN3
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

869250:TOT 020000983
gene id: 869250:TOT_020000983
uniprot id: J4C8G1
names: Similarity
messages: Belongs to the CWC26 family.

869250:TOT 020000127
gene id: 869250:TOT_020000127
uniprot id: J4C356
names: Similarity
messages: Belongs to the peptidase C1 family.

869250:TOT 040000048
gene id: 869250:TOT_040000048
uniprot id: J4CDS8
names: Similarity
messages: Belongs to the amidase family.

869250:TOT 030000513
gene id: 869250:TOT_030000513
uniprot id: J4D984
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

869250:TOT 020000458
gene id: 869250:TOT_020000458
uniprot id: J4C3C4
names: Similarity
messages: Belongs to the DNA polymerase delta/II small subunit family.

869250:TOT 040000978
gene id: 869250:TOT_040000978
uniprot id: J7MC91
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

869250:TOT 010001112
gene id: 869250:TOT_010001112
uniprot id: J4C7U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

869250:TOT 040000624
gene id: 869250:TOT_040000624
uniprot id: J4DQD3
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

869250:TOT 020000976
gene id: 869250:TOT_020000976
uniprot id: J4C3M9
names: Similarity
messages: Belongs to the phosducin family.

869250:TOT 020000484
gene id: 869250:TOT_020000484
uniprot id: J4C860
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010000764
gene id: 869250:TOT_010000764
uniprot id: J4D633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

869250:TOT 030000580
gene id: 869250:TOT_030000580
uniprot id: J4CDK8
names: Function
names: Similarity
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

869250:TOT 010000451
gene id: 869250:TOT_010000451
uniprot id: J4C2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

869250:TOT 040000660
gene id: 869250:TOT_040000660
uniprot id: J4C4J4
names: Similarity
messages: Belongs to the bystin family.

869250:TOT 020001101
gene id: 869250:TOT_020001101
uniprot id: J4D8A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

869250:TOT 040000136
gene id: 869250:TOT_040000136
uniprot id: J4DQ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

869250:TOT 020000936
gene id: 869250:TOT_020000936
uniprot id: J4CD81
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

869250:TOT 020000602
gene id: 869250:TOT_020000602
uniprot id: J4C884
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum

869250:TOT 010000940
gene id: 869250:TOT_010000940
uniprot id: J4D6C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

869250:TOT 030000336
gene id: 869250:TOT_030000336
uniprot id: J4D8Y0
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 030000868
gene id: 869250:TOT_030000868
uniprot id: J4DQ03
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

869250:TOT 040000923
gene id: 869250:TOT_040000923
uniprot id: J4C927
names: Similarity
messages: Belongs to the peptidase M24B family.

869250:TOT 020001040
gene id: 869250:TOT_020001040
uniprot id: J4CCU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

869250:TOT 040000913
gene id: 869250:TOT_040000913
uniprot id: J4CDT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

869250:TOT 020000696
gene id: 869250:TOT_020000696
uniprot id: J4D7Y0
names: Similarity
messages: Belongs to the VAC14 family.

869250:TOT 020000080
gene id: 869250:TOT_020000080
uniprot id: J4DNZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 1 family.
messages: Nucleus

869250:TOT 030000604
gene id: 869250:TOT_030000604
uniprot id: J4CDL3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

869250:TOT 010000474
gene id: 869250:TOT_010000474
uniprot id: J4DNI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

869250:TOT 040000285
gene id: 869250:TOT_040000285
uniprot id: J4DAD5
names: Similarity
messages: Belongs to the heat shock protein 90 family.

869250:TOT 020000418
gene id: 869250:TOT_020000418
uniprot id: J4C3B6
names: Similarity
messages: Belongs to the DENR family.

869250:TOT 040000330
gene id: 869250:TOT_040000330
uniprot id: J4C4C6
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020000239
gene id: 869250:TOT_020000239
uniprot id: J4CCT9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

869250:TOT 010000781
gene id: 869250:TOT_010000781
uniprot id: J4C7N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

869250:TOT 030000564
gene id: 869250:TOT_030000564
uniprot id: J4C3Z6
names: Similarity
messages: Belongs to the peptidase C1 family.

869250:TOT 010000061
gene id: 869250:TOT_010000061
uniprot id: J7M835
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

869250:TOT 010000350
gene id: 869250:TOT_010000350
uniprot id: J4C7E2
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020001057
gene id: 869250:TOT_020001057
uniprot id: J4C844
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020000331
gene id: 869250:TOT_020000331
uniprot id: J4CCV8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

869250:TOT 010001073
gene id: 869250:TOT_010001073
uniprot id: J4DNV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

869250:TOT 020000948
gene id: 869250:TOT_020000948
uniprot id: J4DPH1
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

869250:TOT 020000603
gene id: 869250:TOT_020000603
uniprot id: J4DPA1
names: Similarity
messages: Belongs to the DEAD box helicase family.

869250:TOT 010000623
gene id: 869250:TOT_010000623
uniprot id: J4CCC7
names: Similarity
messages: Belongs to the MCM family.

869250:TOT 040000030
gene id: 869250:TOT_040000030
uniprot id: J4DQ12
names: Similarity
messages: Belongs to the NSRP1 family.

869250:TOT 020000943
gene id: 869250:TOT_020000943
uniprot id: J4DPH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

869250:TOT 030000150
gene id: 869250:TOT_030000150
uniprot id: J4DPL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pym family.
messages: Cytoplasm

869250:TOT 010001038
gene id: 869250:TOT_010001038
uniprot id: J4DNU8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

869250:TOT 010000318
gene id: 869250:TOT_010000318
uniprot id: J4C2K5
names: Similarity
messages: Belongs to the SDO1/SBDS family.

869250:TOT 040000241
gene id: 869250:TOT_040000241
uniprot id: J4C4A8
names: Similarity
messages: Belongs to the RuvB family.

869250:TOT 040000763
gene id: 869250:TOT_040000763
uniprot id: J7MGY6
names: Function
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

869250:TOT 040000627
gene id: 869250:TOT_040000627
uniprot id: J4CE46
names: Similarity
messages: Belongs to the BolA/IbaG family.

869250:TOT 020000055
gene id: 869250:TOT_020000055
uniprot id: J4DNY8
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 010000382
gene id: 869250:TOT_010000382
uniprot id: J4D5E9
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

869250:TOT 010001071
gene id: 869250:TOT_010001071
uniprot id: J4CCL8
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

869250:TOT 010000401
gene id: 869250:TOT_010000401
uniprot id: J4C2M2
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020000188
gene id: 869250:TOT_020000188
uniprot id: J4CCS8
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity.

869250:TOT 020000176
gene id: 869250:TOT_020000176
uniprot id: J4DP12
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869250:TOT 010000494
gene id: 869250:TOT_010000494
uniprot id: J4DNI7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 030000851
gene id: 869250:TOT_030000851
uniprot id: J4C8Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Nucleus

869250:TOT 010000511
gene id: 869250:TOT_010000511
uniprot id: J4C7H5
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

869250:TOT 010000316
gene id: 869250:TOT_010000316
uniprot id: J4DNF1
names: Similarity
messages: Belongs to the ZPR1 family.

869250:TOT 010001123
gene id: 869250:TOT_010001123
uniprot id: J4DNW5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869250:TOT 040000129
gene id: 869250:TOT_040000129
uniprot id: J4CDU4
names: Similarity
messages: Belongs to the VPS29 family.

869250:TOT 010000430
gene id: 869250:TOT_010000430
uniprot id: J4D5H3
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 040000633
gene id: 869250:TOT_040000633
uniprot id: J4DQD5
names: Function
names: Subcellular Location Annotation
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane

869250:TOT 010000056
gene id: 869250:TOT_010000056
uniprot id: J7M833
names: Similarity
messages: Belongs to the NifU family.

869250:TOT 020000074
gene id: 869250:TOT_020000074
uniprot id: J4C7X6
names: Similarity
names: Subunit
messages: Belongs to the NAC-beta family.
messages: Part of the nascent polypeptide-associated complex (NAC).

869250:TOT 040000457
gene id: 869250:TOT_040000457
uniprot id: J4C4F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

869250:TOT 010000707
gene id: 869250:TOT_010000707
uniprot id: J4C7L5
names: Similarity
messages: Belongs to the heat shock protein 90 family.

869250:TOT 020000369
gene id: 869250:TOT_020000369
uniprot id: J4C3A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

869250:TOT 010001251
gene id: 869250:TOT_010001251
uniprot id: J4DNG4
names: Similarity
messages: Belongs to the TBP family.

869250:TOT 010001362
gene id: 869250:TOT_010001362
uniprot id: J4D6M1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

869250:TOT 030000504
gene id: 869250:TOT_030000504
uniprot id: J4C3Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

869250:TOT 010000301
gene id: 869250:TOT_010000301
uniprot id: J4C7D2
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

869250:TOT 030000590
gene id: 869250:TOT_030000590
uniprot id: J4CDL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

869250:TOT 020000228
gene id: 869250:TOT_020000228
uniprot id: J4C377
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

869250:TOT 030000357
gene id: 869250:TOT_030000357
uniprot id: J4DPQ1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869250:TOT 030000241
gene id: 869250:TOT_030000241
uniprot id: J4D8S8
names: Subcellular Location Annotation
messages: Cytoplasm

869250:TOT 040000354
gene id: 869250:TOT_040000354
uniprot id: J4DAG7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 030000905
gene id: 869250:TOT_030000905
uniprot id: J4C3S0
names: Similarity
messages: Belongs to the VPS52 family.

869250:TOT 020000057
gene id: 869250:TOT_020000057
uniprot id: J4C342
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus

869250:TOT 030000649
gene id: 869250:TOT_030000649
uniprot id: J4CDM2
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 030000155
gene id: 869250:TOT_030000155
uniprot id: J4DPL1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

869250:TOT 030000938
gene id: 869250:TOT_030000938
uniprot id: J4DPW3
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

869250:TOT 030000117
gene id: 869250:TOT_030000117
uniprot id: J4D8M0
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 030000822
gene id: 869250:TOT_030000822
uniprot id: J4DPZ4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

869250:TOT 030000211
gene id: 869250:TOT_030000211
uniprot id: J4D8R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

869250:TOT 020000303
gene id: 869250:TOT_020000303
uniprot id: J4C392
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 030000943
gene id: 869250:TOT_030000943
uniprot id: J4C8V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.
messages: coated pit

869250:TOT 030000370
gene id: 869250:TOT_030000370
uniprot id: J4CDG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

869250:TOT 020000833
gene id: 869250:TOT_020000833
uniprot id: J4C8D1
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010000896
gene id: 869250:TOT_010000896
uniprot id: J4D699
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

869250:TOT 020000432
gene id: 869250:TOT_020000432
uniprot id: J4D7G2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

869250:TOT 020000727
gene id: 869250:TOT_020000727
uniprot id: J4C3H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

869250:TOT 030000139
gene id: 869250:TOT_030000139
uniprot id: J4C8J1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

869250:TOT 020000208
gene id: 869250:TOT_020000208
uniprot id: J4CCT2
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 040000881
gene id: 869250:TOT_040000881
uniprot id: J7M8S1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2Fe2S plant-type ferredoxin family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

869250:TOT 010001146
gene id: 869250:TOT_010001146
uniprot id: J4CCN3
names: Similarity
messages: Belongs to the DeSI family.

869250:TOT 010001363
gene id: 869250:TOT_010001363
uniprot id: J4C7V1
names: Similarity
messages: Belongs to the LplA family.

869250:TOT 010001125
gene id: 869250:TOT_010001125
uniprot id: J4C319
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020000941
gene id: 869250:TOT_020000941
uniprot id: J4CD82
names: Similarity
messages: Belongs to the AAA ATPase family.

869250:TOT 010000110
gene id: 869250:TOT_010000110
uniprot id: J7MBW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

869250:TOT 010000718
gene id: 869250:TOT_010000718
uniprot id: J4DNN3
names: Similarity
messages: Belongs to the DEAD box helicase family.

869250:TOT 010000116
gene id: 869250:TOT_010000116
uniprot id: J7M867
names: Similarity
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer.

869250:TOT 020000618
gene id: 869250:TOT_020000618
uniprot id: J4D7U3
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

869250:TOT 020001084
gene id: 869250:TOT_020001084
uniprot id: J4D800
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

869250:TOT 030000565
gene id: 869250:TOT_030000565
uniprot id: J4CDK5
names: Similarity
messages: Belongs to the peptidase C1 family.

869250:TOT 030000227
gene id: 869250:TOT_030000227
uniprot id: J4C3S8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

869250:TOT 040000588
gene id: 869250:TOT_040000588
uniprot id: J4C9A9
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

869250:TOT 030000278
gene id: 869250:TOT_030000278
uniprot id: J4CDE8
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

869250:TOT 020000267
gene id: 869250:TOT_020000267
uniprot id: J4D770
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

869250:TOT 010000181
gene id: 869250:TOT_010000181
uniprot id: J7M8C4
names: Similarity
messages: Belongs to the actin family.

869250:TOT 010001121
gene id: 869250:TOT_010001121
uniprot id: J4CCM8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869250:TOT 020000393
gene id: 869250:TOT_020000393
uniprot id: J4D7E2
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.

869250:TOT 020000290
gene id: 869250:TOT_020000290
uniprot id: J4C820
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 010000743
gene id: 869250:TOT_010000743
uniprot id: J4DNN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRM6/GCD10 family.
messages: Nucleus

869250:TOT 010000955
gene id: 869250:TOT_010000955
uniprot id: J4D6C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

869250:TOT 040000164
gene id: 869250:TOT_040000164
uniprot id: J4CDV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

869250:TOT 010001329
gene id: 869250:TOT_010001329
uniprot id: J4C7R0
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

869250:TOT 030000152
gene id: 869250:TOT_030000152
uniprot id: J4C3R3
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

869250:TOT 010000310
gene id: 869250:TOT_010000310
uniprot id: J4C7D4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

869250:TOT 010000636
gene id: 869250:TOT_010000636
uniprot id: J4D5U0
names: Similarity
messages: Belongs to the WD repeat EIF2A family.

869250:TOT 020000567
gene id: 869250:TOT_020000567
uniprot id: J4C877
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha (regulatory) and two beta (catalytic) chains.

869250:TOT 030000025
gene id: 869250:TOT_030000025
uniprot id: J4C8G8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

869250:TOT 030000044
gene id: 869250:TOT_030000044
uniprot id: J4CDA1
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL41 family.
messages: Component of the large ribosomal subunit.

869250:TOT 040000607
gene id: 869250:TOT_040000607
uniprot id: J4CE42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
messages: Component of the EKC/KEOPS complex; the whole complex dimerizes.
messages: Cytoplasm
messages: Nucleus

869250:TOT 010001126
gene id: 869250:TOT_010001126
uniprot id: J4CCM9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

869250:TOT 020000477
gene id: 869250:TOT_020000477
uniprot id: J4C3C8
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 010000394
gene id: 869250:TOT_010000394
uniprot id: J4DNG7
names: Similarity
messages: Belongs to the IPP transferase family.

869250:TOT 040000099
gene id: 869250:TOT_040000099
uniprot id: J4C909
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

869250:TOT 010000692
gene id: 869250:TOT_010000692
uniprot id: J4CCE1
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 030000298
gene id: 869250:TOT_030000298
uniprot id: J4CDF2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

869250:TOT 040000724
gene id: 869250:TOT_040000724
uniprot id: J7MC88
names: Similarity
messages: Belongs to the peptidase C48 family.

869250:TOT 010000037
gene id: 869250:TOT_010000037
uniprot id: J7M825
names: Similarity
messages: Belongs to the hexokinase family.

869250:TOT 020000402
gene id: 869250:TOT_020000402
uniprot id: J4DP59
names: Function
names: Similarity
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.

869250:TOT 030000867
gene id: 869250:TOT_030000867
uniprot id: J4C8Y6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

869250:TOT 040000723
gene id: 869250:TOT_040000723
uniprot id: J7MGX0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

869250:TOT 020000692
gene id: 869250:TOT_020000692
uniprot id: J4C3H2
names: Similarity
messages: Belongs to the adenylate kinase family.

869250:TOT 010001198
gene id: 869250:TOT_010001198
uniprot id: J7MGJ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869250:TOT 020000389
gene id: 869250:TOT_020000389
uniprot id: J4C3B0
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 040000337
gene id: 869250:TOT_040000337
uniprot id: J4C957
names: Similarity
messages: Belongs to the cullin family.

869250:TOT 010000115
gene id: 869250:TOT_010000115
uniprot id: J7MBW5
names: Function
names: Similarity
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

869250:TOT 010000938
gene id: 869250:TOT_010000938
uniprot id: J4C7R2
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 030000542
gene id: 869250:TOT_030000542
uniprot id: J4DPT8
names: Similarity
messages: Belongs to the peptidase A1 family.

869250:TOT 030000053
gene id: 869250:TOT_030000053
uniprot id: J4C3P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

869250:TOT 030000292
gene id: 869250:TOT_030000292
uniprot id: J4C3U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Nucleus

869250:TOT 040000539
gene id: 869250:TOT_040000539
uniprot id: J4DQB6
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

869250:TOT 020001069
gene id: 869250:TOT_020001069
uniprot id: J4C3E5
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

869250:TOT 010000569
gene id: 869250:TOT_010000569
uniprot id: J4CCB6
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

869250:TOT 020001019
gene id: 869250:TOT_020001019
uniprot id: J4C340
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

869250:TOT 030000256
gene id: 869250:TOT_030000256
uniprot id: J4D8T6
names: Similarity
messages: Belongs to the TMEM121 family.

869250:TOT 040000768
gene id: 869250:TOT_040000768
uniprot id: J7MGY8
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.

869250:TOT 040000541
gene id: 869250:TOT_040000541
uniprot id: J4C4H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

869250:TOT 020001016
gene id: 869250:TOT_020001016
uniprot id: J4C7W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

869250:TOT 010001232
gene id: 869250:TOT_010001232
uniprot id: J7MEX4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

869250:TOT 010000247
gene id: 869250:TOT_010000247
uniprot id: J7MEW5
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

869250:TOT 030000658
gene id: 869250:TOT_030000658
uniprot id: J4C415
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: nucleolus

869250:TOT 010000599
gene id: 869250:TOT_010000599
uniprot id: J4C7J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: Nucleus

869250:TOT 010001288
gene id: 869250:TOT_010001288
uniprot id: J4D5Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

869250:TOT 040000930
gene id: 869250:TOT_040000930
uniprot id: J4C937
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

869250:TOT 020000268
gene id: 869250:TOT_020000268
uniprot id: J4C385
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

869250:TOT 010000349
gene id: 869250:TOT_010000349
uniprot id: J4CC71
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

869250:TOT 020000814
gene id: 869250:TOT_020000814
uniprot id: J4DPE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Heterodimer of two subunits, one of which binds GTP.

869250:TOT 010000226
gene id: 869250:TOT_010000226
uniprot id: J7MEV5
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020000903
gene id: 869250:TOT_020000903
uniprot id: J4DPG2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of the MOCS3/UBA4 homolog, then thiocarboxylated (-COSH) via the rhodanese domain of the MOCS3/UBA4 homolog.
messages: Cytoplasm

869250:TOT 020001067
gene id: 869250:TOT_020001067
uniprot id: J4D7P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the profilin family.
messages: Binds actin.
messages: Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton.
messages: cytoskeleton

869250:TOT 010000450
gene id: 869250:TOT_010000450
uniprot id: J4D5I4
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

869250:TOT 020000199
gene id: 869250:TOT_020000199
uniprot id: J4C801
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

869250:TOT 030000021
gene id: 869250:TOT_030000021
uniprot id: J4DPI4
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

869250:TOT 010001080
gene id: 869250:TOT_010001080
uniprot id: J4C310
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 010001358
gene id: 869250:TOT_010001358
uniprot id: J4CCM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

869250:TOT 010000913
gene id: 869250:TOT_010000913
uniprot id: J4C7Q7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

869250:TOT 010000356
gene id: 869250:TOT_010000356
uniprot id: J4DNF9
names: Similarity
messages: Belongs to the peptidase M1 family.

869250:TOT 010001046
gene id: 869250:TOT_010001046
uniprot id: J4CCL3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

869250:TOT 020001014
gene id: 869250:TOT_020001014
uniprot id: J4C8D9
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

869250:TOT 010000762
gene id: 869250:TOT_010000762
uniprot id: J4C7M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

869250:TOT 040000119
gene id: 869250:TOT_040000119
uniprot id: J4CDU2
names: Subcellular Location Annotation
messages: nucleolus

869250:TOT 030000075
gene id: 869250:TOT_030000075
uniprot id: J4C8H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

869250:TOT 020001062
gene id: 869250:TOT_020001062
uniprot id: J4C3C6
names: Similarity
messages: Belongs to the SF3B5 family.

869250:TOT 010000973
gene id: 869250:TOT_010000973
uniprot id: J4C7R9
names: Subcellular Location Annotation
messages: nucleolus

869250:TOT 030000929
gene id: 869250:TOT_030000929
uniprot id: J4D9B1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

869250:TOT 020000349
gene id: 869250:TOT_020000349
uniprot id: J4C3A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

869250:TOT 020000167
gene id: 869250:TOT_020000167
uniprot id: J4D714
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

869250:TOT 010000605
gene id: 869250:TOT_010000605
uniprot id: J4DNL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

869250:TOT 040000762
gene id: 869250:TOT_040000762
uniprot id: J7M4Q1
names: Similarity
messages: Belongs to the SUI1 family.

869250:TOT 010000019
gene id: 869250:TOT_010000019
uniprot id: J7M4H6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

869250:TOT 040000456
gene id: 869250:TOT_040000456
uniprot id: J4DAM5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

869250:TOT 010000187
gene id: 869250:TOT_010000187
uniprot id: J7MET5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

869250:TOT 040000154
gene id: 869250:TOT_040000154
uniprot id: J4CDU9
names: Similarity
messages: Belongs to the DEAD box helicase family.

869250:TOT 030000252
gene id: 869250:TOT_030000252
uniprot id: J4C3T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

869250:TOT 010000092
gene id: 869250:TOT_010000092
uniprot id: J7MEK8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.

869250:TOT 040000692
gene id: 869250:TOT_040000692
uniprot id: J7MEZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

869250:TOT 010000875
gene id: 869250:TOT_010000875
uniprot id: J4DNR5
names: Similarity
messages: Belongs to the TPPP family.

869250:TOT 020000272
gene id: 869250:TOT_020000272
uniprot id: J4D773
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 020000902
gene id: 869250:TOT_020000902
uniprot id: J4C8E5
names: Similarity
messages: Belongs to the PPP phosphatase family.

869250:TOT 010000179
gene id: 869250:TOT_010000179
uniprot id: J7MGS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NifU family.
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Mitochondrion matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

869250:TOT 020000157
gene id: 869250:TOT_020000157
uniprot id: J4D709
names: Similarity
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.

869250:TOT 040000925
gene id: 869250:TOT_040000925
uniprot id: J4DA89
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS21 family.

869250:TOT 010001153
gene id: 869250:TOT_010001153
uniprot id: J4DNX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

869250:TOT 030000879
gene id: 869250:TOT_030000879
uniprot id: J4D9V1
names: Similarity
messages: Belongs to the archease family.

869250:TOT 030000480
gene id: 869250:TOT_030000480
uniprot id: J4CDI8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

869250:TOT 020000100
gene id: 869250:TOT_020000100
uniprot id: J4DNZ7
names: Similarity
messages: Belongs to the PIGX family.

869250:TOT 030000774
gene id: 869250:TOT_030000774
uniprot id: J4CDP7
names: Function
names: Similarity
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

869250:TOT 010000067
gene id: 869250:TOT_010000067
uniprot id: J7MEJ1
names: Subcellular Location Annotation
messages: Cytoplasm

869250:TOT 020000510
gene id: 869250:TOT_020000510
uniprot id: J4DP81
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020000300
gene id: 869250:TOT_020000300
uniprot id: J4C822
names: Similarity
messages: Belongs to the thymidylate kinase family.

869250:TOT 020000625
gene id: 869250:TOT_020000625
uniprot id: J4CD18
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

869250:TOT 030000410
gene id: 869250:TOT_030000410
uniprot id: J4CDH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

869250:TOT 020000191
gene id: 869250:TOT_020000191
uniprot id: J4D726
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

869250:TOT 020000467
gene id: 869250:TOT_020000467
uniprot id: J4D7I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

869250:TOT 030000207
gene id: 869250:TOT_030000207
uniprot id: J4C3S4
names: Similarity
messages: Belongs to the cullin family.

869250:TOT 010001066
gene id: 869250:TOT_010001066
uniprot id: J4CCL7
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

869250:TOT 040000417
gene id: 869250:TOT_040000417
uniprot id: J4C4E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

869250:TOT 040000339
gene id: 869250:TOT_040000339
uniprot id: J4DAG2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 020000160
gene id: 869250:TOT_020000160
uniprot id: J4C7Z3
names: Similarity
messages: Belongs to the exportin family.

869250:TOT 010000583
gene id: 869250:TOT_010000583
uniprot id: J4C2Q9
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

869250:TOT 020000685
gene id: 869250:TOT_020000685
uniprot id: J4DPB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

869250:TOT 030000486
gene id: 869250:TOT_030000486
uniprot id: J4C8R0
names: Similarity
messages: Belongs to the NAD kinase family.

869250:TOT 030000577
gene id: 869250:TOT_030000577
uniprot id: J4DPU5
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

869250:TOT 010001249
gene id: 869250:TOT_010001249
uniprot id: J4D5E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

869250:TOT 010000137
gene id: 869250:TOT_010000137
uniprot id: J7M4K0
names: Similarity
messages: Belongs to the peptidase M16 family.

869250:TOT 030000161
gene id: 869250:TOT_030000161
uniprot id: J4D8P2
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

869250:TOT 020000552
gene id: 869250:TOT_020000552
uniprot id: J4C874
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

869250:TOT 030000258
gene id: 869250:TOT_030000258
uniprot id: J4CDE4
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

869250:TOT 040000085
gene id: 869250:TOT_040000085
uniprot id: J4DQ23
names: Similarity
messages: Belongs to the MYG1 family.

869250:TOT 030000945
gene id: 869250:TOT_030000945
uniprot id: J4CDP0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

869250:TOT 030000923
gene id: 869250:TOT_030000923
uniprot id: J4CDJ1
names: Similarity
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

869250:TOT 040000963
gene id: 869250:TOT_040000963
uniprot id: J4C4G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

869250:TOT 030000124
gene id: 869250:TOT_030000124
uniprot id: J4C8I8
names: Similarity
messages: Belongs to the MAPRE family.

869250:TOT 040000962
gene id: 869250:TOT_040000962
uniprot id: J4DAR0
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

869250:TOT 020000880
gene id: 869250:TOT_020000880
uniprot id: J4CD70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

869250:TOT 030000377
gene id: 869250:TOT_030000377
uniprot id: J4DPQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP14 family.
messages: Cytoplasm

869250:TOT 020000661
gene id: 869250:TOT_020000661
uniprot id: J4DPB3
names: Similarity
messages: Belongs to the FGGY kinase family.

869250:TOT 010000452
gene id: 869250:TOT_010000452
uniprot id: J4CC92
names: Similarity
messages: Belongs to the MCM family.

869250:TOT 010000577
gene id: 869250:TOT_010000577
uniprot id: J4D5Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

869250:TOT 010000832
gene id: 869250:TOT_010000832
uniprot id: J4D667
names: Function
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

869250:TOT 010000405
gene id: 869250:TOT_010000405
uniprot id: J4D5G1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer.
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

869250:TOT 040000640
gene id: 869250:TOT_040000640
uniprot id: J4C4J0
names: Similarity
messages: Belongs to the CAF1 family.

869250:TOT 040000438
gene id: 869250:TOT_040000438
uniprot id: J4CE07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
messages: Endoplasmic reticulum membrane
messages: Probable GTP-binding protein involved in generating and maintaining the structure of the tubular endoplasmic reticulum network.
messages: Probable GTP-binding protein that may be involved in cell development.

869250:TOT 010001204
gene id: 869250:TOT_010001204
uniprot id: J7M4I2
names: Similarity
messages: Belongs to the OPA3 family.

869250:TOT 030000234
gene id: 869250:TOT_030000234
uniprot id: J4C8L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

869250:TOT 040000454
gene id: 869250:TOT_040000454
uniprot id: J4C981
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Nucleus

869250:TOT 040000634
gene id: 869250:TOT_040000634
uniprot id: J4DAZ1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

869250:TOT 020000383
gene id: 869250:TOT_020000383
uniprot id: J4D7D6
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020000645
gene id: 869250:TOT_020000645
uniprot id: J4C893
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020000231
gene id: 869250:TOT_020000231
uniprot id: J4DP24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

869250:TOT 030000321
gene id: 869250:TOT_030000321
uniprot id: J4D8X2
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 030000309
gene id: 869250:TOT_030000309
uniprot id: J4C8M5
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 020000677
gene id: 869250:TOT_020000677
uniprot id: J4C3G9
names: Similarity
messages: Belongs to the actin family.

869250:TOT 030000333
gene id: 869250:TOT_030000333
uniprot id: J4CDF9
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 020000487
gene id: 869250:TOT_020000487
uniprot id: J4C3D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

869250:TOT 030000919
gene id: 869250:TOT_030000919
uniprot id: J4DPR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

869250:TOT 040000743
gene id: 869250:TOT_040000743
uniprot id: J7MGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Nucleus
messages: spindle

869250:TOT 010000100
gene id: 869250:TOT_010000100
uniprot id: J7MBV7
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

869250:TOT 030000712
gene id: 869250:TOT_030000712
uniprot id: J4C426
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 020000485
gene id: 869250:TOT_020000485
uniprot id: J4DP76
names: Similarity
messages: Belongs to the DEAD box helicase family.

869250:TOT 040000682
gene id: 869250:TOT_040000682
uniprot id: J7MEZ0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

869250:TOT 030000043
gene id: 869250:TOT_030000043
uniprot id: J4C3P1
names: Similarity
messages: Belongs to the protein kinase superfamily.

869250:TOT 020001098
gene id: 869250:TOT_020001098
uniprot id: J4CD75
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

869250:TOT 040000338
gene id: 869250:TOT_040000338
uniprot id: J4DQ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

869250:TOT 010000138
gene id: 869250:TOT_010000138
uniprot id: J7MGQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

869250:TOT 010000453
gene id: 869250:TOT_010000453
uniprot id: J4C7G3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

869250:TOT 040000668
gene id: 869250:TOT_040000668
uniprot id: J4DQE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

869250:TOT 030000784
gene id: 869250:TOT_030000784
uniprot id: J4C440
names: Similarity
messages: Belongs to the SF3A3 family.
messages: Belongs to the class-I fumarase family.

869250:TOT 010000063
gene id: 869250:TOT_010000063
uniprot id: J7M4I5
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010000193
gene id: 869250:TOT_010000193
uniprot id: J7M4L1
names: Similarity
messages: Belongs to the SDHAF4 family.

869250:TOT 040000932
gene id: 869250:TOT_040000932
uniprot id: J4C4A9
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 010000408
gene id: 869250:TOT_010000408
uniprot id: J4C7F4
names: Similarity
messages: Belongs to the dopey family.

869250:TOT 020000059
gene id: 869250:TOT_020000059
uniprot id: J4C7X3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

869250:TOT 020000528
gene id: 869250:TOT_020000528
uniprot id: J4C869
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Membrane

869250:TOT 040000049
gene id: 869250:TOT_040000049
uniprot id: J4C8Z9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

869250:TOT 010001314
gene id: 869250:TOT_010001314
uniprot id: J4D689
names: Similarity
messages: Belongs to the ATPase delta chain family.

869250:TOT 040000125
gene id: 869250:TOT_040000125
uniprot id: J4C914
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 040000195
gene id: 869250:TOT_040000195
uniprot id: J4DQ45
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

869250:TOT 010000801
gene id: 869250:TOT_010000801
uniprot id: J4C7N4
names: Similarity
messages: Belongs to the eIF-2-alpha family.

869250:TOT 030000623
gene id: 869250:TOT_030000623
uniprot id: J4C408
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYF2 family.
messages: Nucleus

869250:TOT 010000838
gene id: 869250:TOT_010000838
uniprot id: J4CCH1
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

869250:TOT 040000517
gene id: 869250:TOT_040000517
uniprot id: J4CE24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

869250:TOT 010000919
gene id: 869250:TOT_010000919
uniprot id: J4DNS4
names: Similarity
messages: Belongs to the type-1 OGG1 family.

869250:TOT 010000708
gene id: 869250:TOT_010000708
uniprot id: J4DNN1
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

869250:TOT 020000775
gene id: 869250:TOT_020000775
uniprot id: J4D825
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

869250:TOT 030000839
gene id: 869250:TOT_030000839
uniprot id: J4C451
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

869250:TOT 030000431
gene id: 869250:TOT_030000431
uniprot id: J4C8P9
names: Similarity
messages: Belongs to the UPP synthase family.

869250:TOT 010000740
gene id: 869250:TOT_010000740
uniprot id: J4C2U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

869250:TOT 020000636
gene id: 869250:TOT_020000636
uniprot id: J4DPA8
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

869250:TOT 030000956
gene id: 869250:TOT_030000956
uniprot id: J4CDR5
names: Similarity
messages: Belongs to the AFG1 ATPase family.

869250:TOT 040000887
gene id: 869250:TOT_040000887
uniprot id: J7M8S3
names: Similarity
messages: Belongs to the CBF/MAK21 family.

869250:TOT 040000644
gene id: 869250:TOT_040000644
uniprot id: J4DAZ8
names: Similarity
messages: Belongs to the RRN3 family.

869250:TOT 030000515
gene id: 869250:TOT_030000515
uniprot id: J4CDJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

869250:TOT 010000686
gene id: 869250:TOT_010000686
uniprot id: J4C2T0
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

869250:TOT 030000617
gene id: 869250:TOT_030000617
uniprot id: J4D9F8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

869250:TOT 040000630
gene id: 869250:TOT_040000630
uniprot id: J4DAY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Nucleus

869250:TOT 010000672
gene id: 869250:TOT_010000672
uniprot id: J4CCD7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

869250:TOT 030000168
gene id: 869250:TOT_030000168
uniprot id: J4CDC6
names: Similarity
messages: Belongs to the MAK16 family.

869250:TOT 030000444
gene id: 869250:TOT_030000444
uniprot id: J4C3X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

869250:TOT 010000188
gene id: 869250:TOT_010000188
uniprot id: J7M4L0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

869250:TOT 040000066
gene id: 869250:TOT_040000066
uniprot id: J4D9Z2
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 040000103
gene id: 869250:TOT_040000103
uniprot id: J4CDT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

869250:TOT 010001013
gene id: 869250:TOT_010001013
uniprot id: J4C7S7
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 020000390
gene id: 869250:TOT_020000390
uniprot id: J4CCX0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

869250:TOT 040000152
gene id: 869250:TOT_040000152
uniprot id: J4DA46
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 020001000
gene id: 869250:TOT_020001000
uniprot id: J4C807
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

869250:TOT 040000482
gene id: 869250:TOT_040000482
uniprot id: J4C4F7
names: Similarity
messages: Belongs to the VPS72/YL1 family.

869250:TOT 010000894
gene id: 869250:TOT_010000894
uniprot id: J4C7Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

869250:TOT 040000769
gene id: 869250:TOT_040000769
uniprot id: J7MCB1
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.

869250:TOT 010001331
gene id: 869250:TOT_010001331
uniprot id: J4DNS9
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

869250:TOT 030000061
gene id: 869250:TOT_030000061
uniprot id: J4DPJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

869250:TOT 040000485
gene id: 869250:TOT_040000485
uniprot id: J4CE17
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020000777
gene id: 869250:TOT_020000777
uniprot id: J4CD49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

869250:TOT 010000175
gene id: 869250:TOT_010000175
uniprot id: J7MC02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

869250:TOT 030000338
gene id: 869250:TOT_030000338
uniprot id: J4CDG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

869250:TOT 010001184
gene id: 869250:TOT_010001184
uniprot id: J7M4L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

869250:TOT 040000816
gene id: 869250:TOT_040000816
uniprot id: J7MF57
names: Similarity
messages: Belongs to the Rab GDI family.

869250:TOT 010000127
gene id: 869250:TOT_010000127
uniprot id: J7MEN2
names: Similarity
messages: Belongs to the WD repeat rae1 family.

869250:TOT 040000993
gene id: 869250:TOT_040000993
uniprot id: J7M4U1
names: Similarity
messages: Belongs to the peptidase C1 family.

869250:TOT 030000927
gene id: 869250:TOT_030000927
uniprot id: J4CDJ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

869250:TOT 040000220
gene id: 869250:TOT_040000220
uniprot id: J4DAA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cell membrane
messages: Cell surface
messages: Membrane
messages: Nucleus
messages: Vacuole
messages: cytoskeleton

869250:TOT 040000649
gene id: 869250:TOT_040000649
uniprot id: J4DB02
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

869250:TOT 020000504
gene id: 869250:TOT_020000504
uniprot id: J4C864
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

869250:TOT 020001032
gene id: 869250:TOT_020001032
uniprot id: J4C7Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

869250:TOT 010001093
gene id: 869250:TOT_010001093
uniprot id: J4DNV9
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

869250:TOT 020000422
gene id: 869250:TOT_020000422
uniprot id: J4D7F6
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.

869250:TOT 030000920
gene id: 869250:TOT_030000920
uniprot id: J4C8Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

869250:TOT 030000189
gene id: 869250:TOT_030000189
uniprot id: J4C8K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

869250:TOT 020000755
gene id: 869250:TOT_020000755
uniprot id: J4D814
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

869250:TOT 010000023
gene id: 869250:TOT_010000023
uniprot id: J7MEG8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

869250:TOT 040000669
gene id: 869250:TOT_040000669
uniprot id: J4DB15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA.
messages: Nucleus

869250:TOT 010000348
gene id: 869250:TOT_010000348
uniprot id: J4C2L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

869250:TOT 020000067
gene id: 869250:TOT_020000067
uniprot id: J4C344
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

869250:TOT 010001229
gene id: 869250:TOT_010001229
uniprot id: J7MGU9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

869250:TOT 010000889
gene id: 869250:TOT_010000889
uniprot id: J4C7Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

869250:TOT 010000920
gene id: 869250:TOT_010000920
uniprot id: J4D6B1
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020000275
gene id: 869250:TOT_020000275
uniprot id: J4C817
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

869250:TOT 020000037
gene id: 869250:TOT_020000037
uniprot id: J4C338
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Cytoplasm

869250:TOT 010001368
gene id: 869250:TOT_010001368
uniprot id: J4C324
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

869250:TOT 040000955
gene id: 869250:TOT_040000955
uniprot id: J4C4E5
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

869250:TOT 030000294
gene id: 869250:TOT_030000294
uniprot id: J4C8M2
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

869250:TOT 030000641
gene id: 869250:TOT_030000641
uniprot id: J4DPV8
names: Similarity
messages: Belongs to the CWC16 family.

869250:TOT 020000189
gene id: 869250:TOT_020000189
uniprot id: J4C7Z9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869250:TOT 030000479
gene id: 869250:TOT_030000479
uniprot id: J4C3X9
names: Similarity
messages: Belongs to the PITHD1 family.

869250:TOT 010000224
gene id: 869250:TOT_010000224
uniprot id: J7MC27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

869250:TOT 040000281
gene id: 869250:TOT_040000281
uniprot id: J4C4B6
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

869250:TOT 040000560
gene id: 869250:TOT_040000560
uniprot id: J4DAU5
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 040000883
gene id: 869250:TOT_040000883
uniprot id: J7M4T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

869250:TOT 030000164
gene id: 869250:TOT_030000164
uniprot id: J4C8J6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

869250:TOT 030000646
gene id: 869250:TOT_030000646
uniprot id: J4DPV9
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

869250:TOT 020000911
gene id: 869250:TOT_020000911
uniprot id: J4CD76
names: Similarity
messages: Belongs to the CBF/MAK21 family.

869250:TOT 020000033
gene id: 869250:TOT_020000033
uniprot id: J4CCP7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

869250:TOT 030000535
gene id: 869250:TOT_030000535
uniprot id: J4CDJ9
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

869250:TOT 020000429
gene id: 869250:TOT_020000429
uniprot id: J4CCX8
names: Similarity
messages: Belongs to the replication factor A protein 1 family.

869250:TOT 040000730
gene id: 869250:TOT_040000730
uniprot id: J7M8K0
names: Similarity
messages: Belongs to the peptidase S14 family.

869250:TOT 010000266
gene id: 869250:TOT_010000266
uniprot id: J7M8G4
names: Similarity
messages: Belongs to the UFM1 family.

869250:TOT 010000218
gene id: 869250:TOT_010000218
uniprot id: J7MGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

869250:TOT 020000595
gene id: 869250:TOT_020000595
uniprot id: J4C3F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

869250:TOT 030000133
gene id: 869250:TOT_030000133
uniprot id: J4CDB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

869250:TOT 010000864
gene id: 869250:TOT_010000864
uniprot id: J4C7P7
names: Similarity
messages: Belongs to the WD repeat SEC31 family.

869250:TOT 020000757
gene id: 869250:TOT_020000757
uniprot id: J4CD45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tic20 family.
messages: Membrane

869250:TOT 010000322
gene id: 869250:TOT_010000322
uniprot id: J4D5C2
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

869250:TOT 020000371
gene id: 869250:TOT_020000371
uniprot id: J4C837
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

869250:TOT 040000419
gene id: 869250:TOT_040000419
uniprot id: J4C974
names: Similarity
messages: Belongs to the PET191 family.

869250:TOT 040000144
gene id: 869250:TOT_040000144
uniprot id: J4CDU7
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 040000599
gene id: 869250:TOT_040000599
uniprot id: J4DQC8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

869250:TOT 030000249
gene id: 869250:TOT_030000249
uniprot id: J4C8L3
names: Similarity
messages: Belongs to the CWC15 family.

869250:TOT 030000055
gene id: 869250:TOT_030000055
uniprot id: J4C8H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus

869250:TOT 040000109
gene id: 869250:TOT_040000109
uniprot id: J4C911
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.

869250:TOT 030000639
gene id: 869250:TOT_030000639
uniprot id: J4CDM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

869250:TOT 010001106
gene id: 869250:TOT_010001106
uniprot id: J4CCM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

869250:TOT 010001280
gene id: 869250:TOT_010001280
uniprot id: J4C7K0
names: Similarity
messages: Belongs to the proteasome subunit S2 family.

869250:TOT 010001070
gene id: 869250:TOT_010001070
uniprot id: J4C308
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020000666
gene id: 869250:TOT_020000666
uniprot id: J4DPB4
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

869250:TOT 040000511
gene id: 869250:TOT_040000511
uniprot id: J4C4G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

869250:TOT 020001087
gene id: 869250:TOT_020001087
uniprot id: J4DPD2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

869250:TOT 010000472
gene id: 869250:TOT_010000472
uniprot id: J4CC96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

869250:TOT 010000797
gene id: 869250:TOT_010000797
uniprot id: J4DNP9
names: Similarity
messages: Belongs to the mTERF family.

869250:TOT 020000652
gene id: 869250:TOT_020000652
uniprot id: J4D7V7
names: Similarity
messages: Belongs to the citrate synthase family.

869250:TOT 020000799
gene id: 869250:TOT_020000799
uniprot id: J4DPE1
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

869250:TOT 010000684
gene id: 869250:TOT_010000684
uniprot id: J4DNM6
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

869250:TOT 020000920
gene id: 869250:TOT_020000920
uniprot id: J4C3L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

869250:TOT 030000373
gene id: 869250:TOT_030000373
uniprot id: J4D901
names: Similarity
messages: Belongs to the DEAD box helicase family.

869250:TOT 040000580
gene id: 869250:TOT_040000580
uniprot id: J4DAV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Vacuole membrane

869250:TOT 040000683
gene id: 869250:TOT_040000683
uniprot id: J7M4M9
names: Subcellular Location Annotation
messages: Cytoplasm

869250:TOT 040000476
gene id: 869250:TOT_040000476
uniprot id: J4DAN7
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

869250:TOT 030000263
gene id: 869250:TOT_030000263
uniprot id: J4CDE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

869250:TOT 010000664
gene id: 869250:TOT_010000664
uniprot id: J4DNM2
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 2 family.

869250:TOT 010000952
gene id: 869250:TOT_010000952
uniprot id: J4CCJ4
names: Similarity
messages: Belongs to the WD repeat EIPR1 family.

869250:TOT 030000615
gene id: 869250:TOT_030000615
uniprot id: J4C8T6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

869250:TOT 030000896
gene id: 869250:TOT_030000896
uniprot id: J4C3P8
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

869250:TOT 020000102
gene id: 869250:TOT_020000102
uniprot id: J4C351
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Nucleus

869250:TOT 040000518
gene id: 869250:TOT_040000518
uniprot id: J4C995
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

869250:TOT 020000339
gene id: 869250:TOT_020000339
uniprot id: J4D7B1
names: Similarity
messages: Belongs to the PPP phosphatase family.

869250:TOT 040000064
gene id: 869250:TOT_040000064
uniprot id: J4C902
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.

869250:TOT 010000215
gene id: 869250:TOT_010000215
uniprot id: J7MC21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

869250:TOT 010001037
gene id: 869250:TOT_010001037
uniprot id: J4C7T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Nucleus

869250:TOT 020000497
gene id: 869250:TOT_020000497
uniprot id: J4C3D2
names: Similarity
messages: Belongs to the Deltex family.

869250:TOT 030000307
gene id: 869250:TOT_030000307
uniprot id: J4C3U4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

869250:TOT 020000135
gene id: 869250:TOT_020000135
uniprot id: J4C7Y8
names: Similarity
messages: Belongs to the ELP3 family.

869250:TOT 020000441
gene id: 869250:TOT_020000441
uniprot id: J4DP67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

869250:TOT 020000045
gene id: 869250:TOT_020000045
uniprot id: J4DNY6
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

869250:TOT 030000813
gene id: 869250:TOT_030000813
uniprot id: J4D9R5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

869250:TOT 040000897
gene id: 869250:TOT_040000897
uniprot id: J4DA94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

869250:TOT 010001096
gene id: 869250:TOT_010001096
uniprot id: J4CCM3
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 020000085
gene id: 869250:TOT_020000085
uniprot id: J4DNZ4
names: Similarity
messages: Belongs to the peptidase C1 family.

869250:TOT 040000322
gene id: 869250:TOT_040000322
uniprot id: J4C4C4
names: Similarity
messages: Belongs to the NifU family.

869250:TOT 020000684
gene id: 869250:TOT_020000684
uniprot id: J4C8A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane

869250:TOT 040000929
gene id: 869250:TOT_040000929
uniprot id: J4CDW6
names: Similarity
messages: Belongs to the protein kinase superfamily.

869250:TOT 010000953
gene id: 869250:TOT_010000953
uniprot id: J4C7R5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

869250:TOT 020001081
gene id: 869250:TOT_020001081
uniprot id: J4D7W9
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

869250:TOT 030000795
gene id: 869250:TOT_030000795
uniprot id: J4CDQ1
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

869250:TOT 040000317
gene id: 869250:TOT_040000317
uniprot id: J4CDY2
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

869250:TOT 040000123
gene id: 869250:TOT_040000123
uniprot id: J4C484
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

869250:TOT 040000534
gene id: 869250:TOT_040000534
uniprot id: J4DQB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

869250:TOT 020000284
gene id: 869250:TOT_020000284
uniprot id: J4CCU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

869250:TOT 020000801
gene id: 869250:TOT_020000801
uniprot id: J4C3J4
names: Subcellular Location Annotation
messages: nucleolus

869250:TOT 040000991
gene id: 869250:TOT_040000991
uniprot id: J7MH34
names: Subcellular Location Annotation
messages: Cytoplasm

869250:TOT 040000956
gene id: 869250:TOT_040000956
uniprot id: J4DQ96
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

869250:TOT 040000159
gene id: 869250:TOT_040000159
uniprot id: J4CDV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

869250:TOT 020000078
gene id: 869250:TOT_020000078
uniprot id: J4CCQ6
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

869250:TOT 030000230
gene id: 869250:TOT_030000230
uniprot id: J4DPM6
names: Subcellular Location Annotation
messages: nucleolus

869250:TOT 010000936
gene id: 869250:TOT_010000936
uniprot id: J4C2Y1
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.

869250:TOT 040000737
gene id: 869250:TOT_040000737
uniprot id: J7M4P3
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

869250:TOT 010000742
gene id: 869250:TOT_010000742
uniprot id: J4C7M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

869250:TOT 020000669
gene id: 869250:TOT_020000669
uniprot id: J4CD27
names: Function
names: Similarity
messages: Belongs to the calmodulin family.
messages: May be involved in calcium-mediated signal transduction.

869250:TOT 010001040
gene id: 869250:TOT_010001040
uniprot id: J4C302
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

869250:TOT 020000474
gene id: 869250:TOT_020000474
uniprot id: J4CCY7
names: Similarity
messages: Belongs to the p23/wos2 family.

869250:TOT 020000954
gene id: 869250:TOT_020000954
uniprot id: J4D8C0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

869250:TOT 020000619
gene id: 869250:TOT_020000619
uniprot id: J4C3F7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

869250:TOT 030000510
gene id: 869250:TOT_030000510
uniprot id: J4CDJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

869250:TOT 010001222
gene id: 869250:TOT_010001222
uniprot id: J7MGS8
names: Similarity
messages: Belongs to the ATPase gamma chain family.

869250:TOT 030000383
gene id: 869250:TOT_030000383
uniprot id: J4D906
names: Similarity
messages: Belongs to the NEMF family.

869250:TOT 030000563
gene id: 869250:TOT_030000563
uniprot id: J4D9B8
names: Similarity
messages: Belongs to the peptidase C1 family.

869250:TOT 030000953
gene id: 869250:TOT_030000953
uniprot id: J4D9S0
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

869250:TOT 040000436
gene id: 869250:TOT_040000436
uniprot id: J4DAL4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

869250:TOT 020000535
gene id: 869250:TOT_020000535
uniprot id: J4D7N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

869250:TOT 040000878
gene id: 869250:TOT_040000878
uniprot id: J7M4T6
names: Similarity
messages: Belongs to the SNF8 family.
messages: Belongs to the universal ribosomal protein uL16 family.

869250:TOT 020001047
gene id: 869250:TOT_020001047
uniprot id: J4C397
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

869250:TOT 040000230
gene id: 869250:TOT_040000230
uniprot id: J4DAA7
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

869250:TOT 020000256
gene id: 869250:TOT_020000256
uniprot id: J4DP29
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

869250:TOT 040000547
gene id: 869250:TOT_040000547
uniprot id: J4CE30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

869250:TOT 020000250
gene id: 869250:TOT_020000250
uniprot id: J4C812
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus

869250:TOT 040000293
gene id: 869250:TOT_040000293
uniprot id: J4C948
names: Similarity
messages: Belongs to the CDC123 family.

869250:TOT 040000502
gene id: 869250:TOT_040000502
uniprot id: J4CE21
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

869250:TOT 010000131
gene id: 869250:TOT_010000131
uniprot id: J7M876
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

869250:TOT 020000513
gene id: 869250:TOT_020000513
uniprot id: J4CCZ5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

869250:TOT 030000059
gene id: 869250:TOT_030000059
uniprot id: J4CDA4
names: Similarity
messages: Belongs to the SAP18 family.

869250:TOT 040000331
gene id: 869250:TOT_040000331
uniprot id: J4CDY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCR10/QCR9 family.
messages: Membrane
messages: Mitochondrion inner membrane

869250:TOT 020000942
gene id: 869250:TOT_020000942
uniprot id: J4C8F3
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 040000374
gene id: 869250:TOT_040000374
uniprot id: J4DAH7
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

869250:TOT 010000706
gene id: 869250:TOT_010000706
uniprot id: J4CCE4
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

869250:TOT 010000589
gene id: 869250:TOT_010000589
uniprot id: J4C7J1
names: Similarity
messages: Belongs to the FAM76 family.

869250:TOT 040000733
gene id: 869250:TOT_040000733
uniprot id: J7MGX4
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

869250:TOT 010000912
gene id: 869250:TOT_010000912
uniprot id: J4CCI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NCBP2 family.
messages: Nucleus

869250:TOT 010000372
gene id: 869250:TOT_010000372
uniprot id: J4D5E5
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

869250:TOT 040000291
gene id: 869250:TOT_040000291
uniprot id: J4C4B8
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

869250:TOT 020000062
gene id: 869250:TOT_020000062
uniprot id: J4C343
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

869250:TOT 040000192
gene id: 869250:TOT_040000192
uniprot id: J4C498
names: Subcellular Location Annotation
messages: nuclear pore complex

869250:TOT 020000408
gene id: 869250:TOT_020000408
uniprot id: J4C3B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: coated pit

869250:TOT 040000569
gene id: 869250:TOT_040000569
uniprot id: J4DQC2
names: Similarity
messages: Belongs to the activator 1 small subunits family.

869250:TOT 010001245
gene id: 869250:TOT_010001245
uniprot id: J4D5B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

869250:TOT 020000745
gene id: 869250:TOT_020000745
uniprot id: J4DPD0
names: Similarity
messages: Belongs to the PITHD1 family.

869250:TOT 030000734
gene id: 869250:TOT_030000734
uniprot id: J4CDN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm

869250:TOT 020001024
gene id: 869250:TOT_020001024
uniprot id: J4CCR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

869250:TOT 010000744
gene id: 869250:TOT_010000744
uniprot id: J4D612
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

869250:TOT 030000040
gene id: 869250:TOT_030000040
uniprot id: J4C8H1
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

869250:TOT 020000955
gene id: 869250:TOT_020000955
uniprot id: J4C3M5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

869250:TOT 010000198
gene id: 869250:TOT_010000198
uniprot id: J7M4L2
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

869250:TOT 010000568
gene id: 869250:TOT_010000568
uniprot id: J4C2Q6
names: Similarity
messages: Belongs to the COG4 family.

869250:TOT 010001190
gene id: 869250:TOT_010001190
uniprot id: J4C2S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

869250:TOT 030000205
gene id: 869250:TOT_030000205
uniprot id: J4DPM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

869250:TOT 010000651
gene id: 869250:TOT_010000651
uniprot id: J4C2S3
names: Subcellular Location Annotation
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane

869250:TOT 040000257
gene id: 869250:TOT_040000257
uniprot id: J4CDX0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

869250:TOT 040000490
gene id: 869250:TOT_040000490
uniprot id: J4CE18
names: Similarity
messages: Belongs to the PPP phosphatase family. BSU subfamily.

869250:TOT 040000440
gene id: 869250:TOT_040000440
uniprot id: J4DQ95
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

869250:TOT 010000235
gene id: 869250:TOT_010000235
uniprot id: J7M8E9
names: Similarity
messages: Belongs to the tRNA(His) guanylyltransferase family.

869250:TOT 020000557
gene id: 869250:TOT_020000557
uniprot id: J4C875
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

869250:TOT 040000585
gene id: 869250:TOT_040000585
uniprot id: J4DAW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

869250:TOT 020000137
gene id: 869250:TOT_020000137
uniprot id: J4D700
names: Similarity
messages: Belongs to the heat shock protein 70 family.

869250:TOT 030000780
gene id: 869250:TOT_030000780
uniprot id: J4C8W9
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010000199
gene id: 869250:TOT_010000199
uniprot id: J7MGT2
names: Similarity
messages: Belongs to the BCP1 family.

869250:TOT 020000276
gene id: 869250:TOT_020000276
uniprot id: J4DP33
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

869250:TOT 020000950
gene id: 869250:TOT_020000950
uniprot id: J4C3M4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

869250:TOT 030000125
gene id: 869250:TOT_030000125
uniprot id: J4DPK5
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010000933
gene id: 869250:TOT_010000933
uniprot id: J4C7R1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

869250:TOT 020000365
gene id: 869250:TOT_020000365
uniprot id: J4CCW5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

869250:TOT 040000802
gene id: 869250:TOT_040000802
uniprot id: J7M4R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

869250:TOT 040000435
gene id: 869250:TOT_040000435
uniprot id: J4DQ94
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

869250:TOT 030000906
gene id: 869250:TOT_030000906
uniprot id: J4CDD0
names: Similarity
messages: Belongs to the V-ATPase G subunit family.

869250:TOT 030000690
gene id: 869250:TOT_030000690
uniprot id: J4DPW8
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

869250:TOT 030000375
gene id: 869250:TOT_030000375
uniprot id: J4CDG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

869250:TOT 020000285
gene id: 869250:TOT_020000285
uniprot id: J4C819
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

869250:TOT 040000918
gene id: 869250:TOT_040000918
uniprot id: J4C481
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB4 family.
messages: Nucleus

869250:TOT 040000944
gene id: 869250:TOT_040000944
uniprot id: J4DAF5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

869250:TOT 030000334
gene id: 869250:TOT_030000334
uniprot id: J4C8N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS3/PSF3 family.
messages: Nucleus

869250:TOT 020001033
gene id: 869250:TOT_020001033
uniprot id: J4D734
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRT-like transporter family.
messages: Membrane

869250:TOT 010001277
gene id: 869250:TOT_010001277
uniprot id: J4CCC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus

869250:TOT 010000241
gene id: 869250:TOT_010000241
uniprot id: J7MEW3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

869250:TOT 030000777
gene id: 869250:TOT_030000777
uniprot id: J4D9P5
names: Similarity
messages: Belongs to the CWC16 family.

869250:TOT 010000806
gene id: 869250:TOT_010000806
uniprot id: J4CCG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Belongs to the NAF1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

869250:TOT 020001046
gene id: 869250:TOT_020001046
uniprot id: J4D7A4
names: Similarity
messages: Belongs to the ATG8 family.

869250:TOT 030000064
gene id: 869250:TOT_030000064
uniprot id: J4CDA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

869250:TOT 010000268
gene id: 869250:TOT_010000268
uniprot id: J7M4M6
names: Similarity
messages: Belongs to the AAA ATPase family.

869250:TOT 030000136
gene id: 869250:TOT_030000136
uniprot id: J4D8N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

869250:TOT 030000429
gene id: 869250:TOT_030000429
uniprot id: J4C3W9
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.

869250:TOT 020000129
gene id: 869250:TOT_020000129
uniprot id: J4C7Y7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

869250:TOT 020000111
gene id: 869250:TOT_020000111
uniprot id: J4D6Z0
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

869250:TOT 010000745
gene id: 869250:TOT_010000745
uniprot id: J4C2U2
names: Similarity
messages: Belongs to the actin family.

869250:TOT 020000149
gene id: 869250:TOT_020000149
uniprot id: J4CCS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

869250:TOT 040000648
gene id: 869250:TOT_040000648
uniprot id: J4DQD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

869250:TOT 040000104
gene id: 869250:TOT_040000104
uniprot id: J4C910
names: Similarity
messages: Belongs to the peptidase T1A family.

869250:TOT 020000695
gene id: 869250:TOT_020000695
uniprot id: J4DPC0
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

869250:TOT 030000296
gene id: 869250:TOT_030000296
uniprot id: J4D8V9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

869250:TOT 030000863
gene id: 869250:TOT_030000863
uniprot id: J4DQ02
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

869250:TOT 040000029
gene id: 869250:TOT_040000029
uniprot id: J4C8Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Nucleus

869250:TOT 010000628
gene id: 869250:TOT_010000628
uniprot id: J4CCC8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

869250:TOT 030000122
gene id: 869250:TOT_030000122
uniprot id: J4C3Q7
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

869250:TOT 010000776
gene id: 869250:TOT_010000776
uniprot id: J4CCF8
names: Similarity
messages: Belongs to the DEAD box helicase family.

869250:TOT 020000506
gene id: 869250:TOT_020000506
uniprot id: J4D7K9
names: Similarity
messages: Belongs to the Luc7 family.

869250:TOT 040000685
gene id: 869250:TOT_040000685
uniprot id: J7MC67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0235 family.
messages: Membrane

869250:TOT 010001124
gene id: 869250:TOT_010001124
uniprot id: J4D6M5
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

869250:TOT 030000894
gene id: 869250:TOT_030000894
uniprot id: J4DPI6
names: Similarity
messages: Belongs to the MOG1 family.

869250:TOT 010000293
gene id: 869250:TOT_010000293
uniprot id: J4D5B0
names: Similarity
messages: Belongs to the peptidase S1C family.

869250:TOT 010000847
gene id: 869250:TOT_010000847
uniprot id: J4C2W3
names: Similarity
messages: Belongs to the NOC2 family.

869250:TOT 010000174
gene id: 869250:TOT_010000174
uniprot id: J7MGS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

869250:TOT 040000399
gene id: 869250:TOT_040000399
uniprot id: J4C970
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

869250:TOT 030000665
gene id: 869250:TOT_030000665
uniprot id: J4C8U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

869250:TOT 010000519
gene id: 869250:TOT_010000519
uniprot id: J4C2P6
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

869250:TOT 010001031
gene id: 869250:TOT_010001031
uniprot id: J4CCL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

869250:TOT 020000498
gene id: 869250:TOT_020000498
uniprot id: J4CCZ2
names: Similarity
messages: Belongs to the SNW family.

869250:TOT 010000299
gene id: 869250:TOT_010000299
uniprot id: J4C2K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

869250:TOT 010001294
gene id: 869250:TOT_010001294
uniprot id: J4C2U6
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

869250:TOT 040000077
gene id: 869250:TOT_040000077
uniprot id: J4C475
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Cytoplasm
messages: nucleolus

869250:TOT 040000093
gene id: 869250:TOT_040000093
uniprot id: J4CDT7
names: Similarity
messages: Belongs to the Iojap/RsfS family.

869250:TOT 010000665
gene id: 869250:TOT_010000665
uniprot id: J4D5W0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

869250:TOT 010000039
gene id: 869250:TOT_010000039
uniprot id: J7M4I0
names: Similarity
messages: Belongs to the hexokinase family.

869250:TOT 010000272
gene id: 869250:TOT_010000272
uniprot id: J4DNE2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

869250:TOT 040000480
gene id: 869250:TOT_040000480
uniprot id: J4DQA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

869250:TOT 040000621
gene id: 869250:TOT_040000621
uniprot id: J4C4I6
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

869250:TOT 010000359
gene id: 869250:TOT_010000359
uniprot id: J4CC73
names: Similarity
messages: Belongs to the ANP32 family.

869250:TOT 010001156
gene id: 869250:TOT_010001156
uniprot id: J4CCN5
names: Similarity
messages: Belongs to the cyclin family.

869250:TOT 040000213
gene id: 869250:TOT_040000213
uniprot id: J4C932
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

869250:TOT 030000903
gene id: 869250:TOT_030000903
uniprot id: J4DPL5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

869250:TOT 020000223
gene id: 869250:TOT_020000223
uniprot id: J4DP22
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

869250:TOT 010000772
gene id: 869250:TOT_010000772
uniprot id: J4C7M8
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 040000968
gene id: 869250:TOT_040000968
uniprot id: J4C4I8
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 040000530
gene id: 869250:TOT_040000530
uniprot id: J4DAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

869250:TOT 040000632
gene id: 869250:TOT_040000632
uniprot id: J4C9B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

869250:TOT 040000147
gene id: 869250:TOT_040000147
uniprot id: J4DA42
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 020000496
gene id: 869250:TOT_020000496
uniprot id: J4D7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

869250:TOT 030000697
gene id: 869250:TOT_030000697
uniprot id: J4C423
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

869250:TOT 040000946
gene id: 869250:TOT_040000946
uniprot id: J4CDY4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

869250:TOT 020000896
gene id: 869250:TOT_020000896
uniprot id: J4CD73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Enzyme with a broad specificity.
messages: Membrane

869250:TOT 010000265
gene id: 869250:TOT_010000265
uniprot id: J7MC49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family.
messages: Nucleus

869250:TOT 030000519
gene id: 869250:TOT_030000519
uniprot id: J4C3Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

869250:TOT 010000467
gene id: 869250:TOT_010000467
uniprot id: J4CC95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: nuclear pore complex

869250:TOT 030000633
gene id: 869250:TOT_030000633
uniprot id: J4C410
names: Similarity
messages: Belongs to the DEAD box helicase family.

869250:TOT 010000960
gene id: 869250:TOT_010000960
uniprot id: J4D6D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Membrane

869250:TOT 020000420
gene id: 869250:TOT_020000420
uniprot id: J4C847
names: Similarity
messages: Belongs to the DEAD box helicase family.

869250:TOT 010000373
gene id: 869250:TOT_010000373
uniprot id: J4C2L6
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

869250:TOT 040000833
gene id: 869250:TOT_040000833
uniprot id: J7MH17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

869250:TOT 020000973
gene id: 869250:TOT_020000973
uniprot id: J4C8F9
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 010001316
gene id: 869250:TOT_010001316
uniprot id: J4D691
names: Similarity
messages: Belongs to the heat shock protein 90 family.

869250:TOT 020001018
gene id: 869250:TOT_020001018
uniprot id: J4DNY5
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

869250:TOT 010001183
gene id: 869250:TOT_010001183
uniprot id: J7M4J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

869250:TOT 010000050
gene id: 869250:TOT_010000050
uniprot id: J7MBT7
names: Similarity
messages: Belongs to the DEAD box helicase family.

869250:TOT 010000615
gene id: 869250:TOT_010000615
uniprot id: J4DNL2
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

869250:TOT 030000134
gene id: 869250:TOT_030000134
uniprot id: J4C8J0
names: Function
names: Similarity
messages: Belongs to the WD repeat CIA1 family.
messages: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.

869250:TOT 030000147
gene id: 869250:TOT_030000147
uniprot id: J4C3R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

869250:TOT 010000238
gene id: 869250:TOT_010000238
uniprot id: J7MGU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal TPase family.
messages: Nucleus

869250:TOT 040000661
gene id: 869250:TOT_040000661
uniprot id: J4CE53
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

869250:TOT 010001002
gene id: 869250:TOT_010001002
uniprot id: J4CCK4
names: Similarity
messages: Belongs to the CEF1 family.

869250:TOT 040000095
gene id: 869250:TOT_040000095
uniprot id: J4DQ25
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

869250:TOT 010001026
gene id: 869250:TOT_010001026
uniprot id: J4C2Z9
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

869250:TOT 030000765
gene id: 869250:TOT_030000765
uniprot id: J4C8W6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

869250:TOT 020000226
gene id: 869250:TOT_020000226
uniprot id: J4CCT6
names: Similarity
messages: Belongs to the heat shock protein 90 family.

869250:TOT 020000951
gene id: 869250:TOT_020000951
uniprot id: J4CD84
names: Similarity
messages: Belongs to the phosphohexose mutase family.

869250:TOT 030000747
gene id: 869250:TOT_030000747
uniprot id: J4D9M6
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

869250:TOT 030000057
gene id: 869250:TOT_030000057
uniprot id: J4D8I0
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 040000950
gene id: 869250:TOT_040000950
uniprot id: J4C4C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

869250:TOT 020000025
gene id: 869250:TOT_020000025
uniprot id: J4DNY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

869250:TOT 030000260
gene id: 869250:TOT_030000260
uniprot id: J4DPN2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

869250:TOT 030000637
gene id: 869250:TOT_030000637
uniprot id: J4D9G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

869250:TOT 010001303
gene id: 869250:TOT_010001303
uniprot id: J4C2V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

869250:TOT 030000372
gene id: 869250:TOT_030000372
uniprot id: J4DPQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

869250:TOT 010000991
gene id: 869250:TOT_010000991
uniprot id: J4C2Z2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869250:TOT 010000783
gene id: 869250:TOT_010000783
uniprot id: J4D643
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

869250:TOT 010000503
gene id: 869250:TOT_010000503
uniprot id: J4D5L5
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 030000445
gene id: 869250:TOT_030000445
uniprot id: J4CDI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

869250:TOT 040000880
gene id: 869250:TOT_040000880
uniprot id: J7MCH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

869250:TOT 020000794
gene id: 869250:TOT_020000794
uniprot id: J4DPE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

869250:TOT 040000594
gene id: 869250:TOT_040000594
uniprot id: J4DQC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

869250:TOT 010000196
gene id: 869250:TOT_010000196
uniprot id: J7M8D2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

869250:TOT 030000738
gene id: 869250:TOT_030000738
uniprot id: J4C431
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

869250:TOT 010000167
gene id: 869250:TOT_010000167
uniprot id: J7MES4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS11 family.
messages: chloroplast

869250:TOT 040000407
gene id: 869250:TOT_040000407
uniprot id: J4C4E2
names: Similarity
messages: Belongs to the MCM family.

869250:TOT 040000701
gene id: 869250:TOT_040000701
uniprot id: J7M8I7
names: Subcellular Location Annotation
messages: Membrane

869250:TOT 020001017
gene id: 869250:TOT_020001017
uniprot id: J4C7W6
names: Similarity
messages: Belongs to the yippee family.

869250:TOT 020001050
gene id: 869250:TOT_020001050
uniprot id: J4C399
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: nucleolus
messages: nucleoplasm

869250:TOT 030000434
gene id: 869250:TOT_030000434
uniprot id: J4C3X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

869250:TOT 020000874
gene id: 869250:TOT_020000874
uniprot id: J4C3K9
names: Similarity
messages: Belongs to the PA28 family.

869250:TOT 040000556
gene id: 869250:TOT_040000556
uniprot id: J4C4H3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 010000649
gene id: 869250:TOT_010000649
uniprot id: J4DNL9
names: Similarity
messages: Belongs to the VPS28 family.

869250:TOT 030000029
gene id: 869250:TOT_030000029
uniprot id: J4CD98
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

869250:TOT 030000376
gene id: 869250:TOT_030000376
uniprot id: J4C8N8
names: Similarity
messages: Belongs to the SUA5 family.

869250:TOT 020000218
gene id: 869250:TOT_020000218
uniprot id: J4CCT4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.

869250:TOT 010001219
gene id: 869250:TOT_010001219
uniprot id: J7MES7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Cytoplasm

869250:TOT 010000271
gene id: 869250:TOT_010000271
uniprot id: J7M8G7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

869250:TOT 010000885
gene id: 869250:TOT_010000885
uniprot id: J4DNR7
names: Similarity
messages: Belongs to the SRR1 family.

869250:TOT 030000612
gene id: 869250:TOT_030000612
uniprot id: J4D9F5
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.

869250:TOT 010000724
gene id: 869250:TOT_010000724
uniprot id: J4D5Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

869250:TOT 010000147
gene id: 869250:TOT_010000147
uniprot id: J7M4K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: nucleolus

869250:TOT 030000069
gene id: 869250:TOT_030000069
uniprot id: J4CDA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

869250:TOT 010000895
gene id: 869250:TOT_010000895
uniprot id: J4DNR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

869250:TOT 040000578
gene id: 869250:TOT_040000578
uniprot id: J4C9A7
names: Similarity
messages: Belongs to the SLBP family.

869250:TOT 040000375
gene id: 869250:TOT_040000375
uniprot id: J4C4D5
names: Similarity
messages: Belongs to the MEMO1 family.

869250:TOT 010001216
gene id: 869250:TOT_010001216
uniprot id: J7MGR7
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

869250:TOT 040000596
gene id: 869250:TOT_040000596
uniprot id: J4C4I1
names: Similarity
messages: Belongs to the CDC73 family.

869250:TOT 020001072
gene id: 869250:TOT_020001072
uniprot id: J4C887
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

869250:TOT 020000364
gene id: 869250:TOT_020000364
uniprot id: J4C3A5
names: Similarity
messages: Belongs to the PPC synthetase family.

869250:TOT 020000027
gene id: 869250:TOT_020000027
uniprot id: J4C336
names: Similarity
messages: Belongs to the SLBP family.

869250:TOT 040000582
gene id: 869250:TOT_040000582
uniprot id: J4CE37
names: Subcellular Location Annotation
messages: Nucleus

869250:TOT 030000306
gene id: 869250:TOT_030000306
uniprot id: J4D8W4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

869250:TOT 010000638
gene id: 869250:TOT_010000638
uniprot id: J4CCD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

869250:TOT 030000030
gene id: 869250:TOT_030000030
uniprot id: J4C8G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

869250:TOT 030000423
gene id: 869250:TOT_030000423
uniprot id: J4D930
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

869250:TOT 010001337
gene id: 869250:TOT_010001337
uniprot id: J4C2Y8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 040000943
gene id: 869250:TOT_040000943
uniprot id: J4DQ69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

869250:TOT 020000368
gene id: 869250:TOT_020000368
uniprot id: J4D7C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

869250:TOT 020000853
gene id: 869250:TOT_020000853
uniprot id: J4C8D5
names: Similarity
messages: Belongs to the PIGH family.

869250:TOT 010000024
gene id: 869250:TOT_010000024
uniprot id: J7M4H7
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

869250:TOT 010001309
gene id: 869250:TOT_010001309
uniprot id: J4C7P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

869250:TOT 040000416
gene id: 869250:TOT_040000416
uniprot id: J4DAK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

869250:TOT 030000674
gene id: 869250:TOT_030000674
uniprot id: J4CDM7
names: Similarity
messages: Belongs to the CAP family.

869250:TOT 040000670
gene id: 869250:TOT_040000670
uniprot id: J4C4J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pescadillo family.
messages: Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
messages: nucleolus
messages: nucleoplasm

869250:TOT 040000365
gene id: 869250:TOT_040000365
uniprot id: J4C4D3
names: Similarity
messages: Belongs to the peptidase M17 family.

869250:TOT 040000767
gene id: 869250:TOT_040000767
uniprot id: J7M4Q2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

869250:TOT 010000245
gene id: 869250:TOT_010000245
uniprot id: J7MC38
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

869250:TOT 020000414
gene id: 869250:TOT_020000414
uniprot id: J4CCX5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

869250:TOT 020000646
gene id: 869250:TOT_020000646
uniprot id: J4DPB0
names: Subcellular Location Annotation
messages: nucleolus

869250:TOT 020000419
gene id: 869250:TOT_020000419
uniprot id: J4CCX6
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

869250:TOT 010000170
gene id: 869250:TOT_010000170
uniprot id: J7MC00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP11 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

869250:TOT 020001034
gene id: 869250:TOT_020001034
uniprot id: J4D745
names: Similarity
messages: Belongs to the SCO1/2 family.

869250:TOT 020000614
gene id: 869250:TOT_020000614
uniprot id: J4C3F6
names: Subcellular Location Annotation
messages: Cell surface

869250:TOT 040000458
gene id: 869250:TOT_040000458
uniprot id: J4CE11
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

869250:TOT 030000280
gene id: 869250:TOT_030000280
uniprot id: J4DPN6
names: Similarity
messages: Belongs to the UFL1 family.

869250:TOT 010000746
gene id: 869250:TOT_010000746
uniprot id: J4CCF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

869250:TOT 010000714
gene id: 869250:TOT_010000714
uniprot id: J4D5Z1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

869250:TOT 010001194
gene id: 869250:TOT_010001194
uniprot id: J4C2V5
names: Similarity
messages: Belongs to the UQCRB/QCR7 family.