869211:SPITH RS00770
gene id: 869211:SPITH_RS00770
uniprot id: G0GC78
names: Similarity
messages: Belongs to the peptidase S16 family.

869211:SPITH RS07240
gene id: 869211:SPITH_RS07240
uniprot id: G0G9Z7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS06860
gene id: 869211:SPITH_RS06860
uniprot id: G0GFS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS11150
gene id: 869211:SPITH_RS11150
uniprot id: G0GFP3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

869211:SPITH RS00110
gene id: 869211:SPITH_RS00110
uniprot id: G0GBF1
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS03140
gene id: 869211:SPITH_RS03140
uniprot id: G0GA55
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

869211:SPITH RS01395
gene id: 869211:SPITH_RS01395
uniprot id: G0GDD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

869211:SPITH RS11695
gene id: 869211:SPITH_RS11695
uniprot id: G0GG70
names: Similarity
messages: Belongs to the ParB family.

869211:SPITH RS08555
gene id: 869211:SPITH_RS08555
uniprot id: G0GBC9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

869211:SPITH RS10050
gene id: 869211:SPITH_RS10050
uniprot id: G0GDV0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

869211:SPITH RS11245
gene id: 869211:SPITH_RS11245
uniprot id: G0GFY5
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS01910
gene id: 869211:SPITH_RS01910
uniprot id: G0GE32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

869211:SPITH RS11810
gene id: 869211:SPITH_RS11810
uniprot id: G0GAU5
names: Similarity
messages: Belongs to the bacterial secretin family.

869211:SPITH RS07290
gene id: 869211:SPITH_RS07290
uniprot id: G0GA05
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

869211:SPITH RS10620
gene id: 869211:SPITH_RS10620
uniprot id: G0GEZ8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

869211:SPITH RS08285
gene id: 869211:SPITH_RS08285
uniprot id: G0GB75
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS10380
gene id: 869211:SPITH_RS10380
uniprot id: G0GEF9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS10170
gene id: 869211:SPITH_RS10170
uniprot id: G0GEB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

869211:SPITH RS10060
gene id: 869211:SPITH_RS10060
uniprot id: G0GDV2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

869211:SPITH RS01875
gene id: 869211:SPITH_RS01875
uniprot id: G0GE26
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

869211:SPITH RS07055
gene id: 869211:SPITH_RS07055
uniprot id: G0GFV8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

869211:SPITH RS10895
gene id: 869211:SPITH_RS10895
uniprot id: G0GFJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

869211:SPITH RS05635
gene id: 869211:SPITH_RS05635
uniprot id: G0GDN4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

869211:SPITH RS02365
gene id: 869211:SPITH_RS02365
uniprot id: G0GF52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

869211:SPITH RS05220
gene id: 869211:SPITH_RS05220
uniprot id: G0GD06
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

869211:SPITH RS04775
gene id: 869211:SPITH_RS04775
uniprot id: G0GCC7
names: Subcellular Location Annotation
messages: Cytoplasm

869211:SPITH RS10460
gene id: 869211:SPITH_RS10460
uniprot id: G0GEH5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

869211:SPITH RS03325
gene id: 869211:SPITH_RS03325
uniprot id: G0GA92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

869211:SPITH RS11790
gene id: 869211:SPITH_RS11790
uniprot id: G0GAR4
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS03050
gene id: 869211:SPITH_RS03050
uniprot id: G0G9Y0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

869211:SPITH RS10120
gene id: 869211:SPITH_RS10120
uniprot id: G0GEA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

869211:SPITH RS08075
gene id: 869211:SPITH_RS08075
uniprot id: G0GAU4
names: Similarity
messages: Belongs to the GSP E family.

869211:SPITH RS10475
gene id: 869211:SPITH_RS10475
uniprot id: G0GEX1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

869211:SPITH RS04735
gene id: 869211:SPITH_RS04735
uniprot id: G0GCB9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

869211:SPITH RS10670
gene id: 869211:SPITH_RS10670
uniprot id: G0GF08
names: Similarity
messages: Belongs to the ribulokinase family.

869211:SPITH RS11200
gene id: 869211:SPITH_RS11200
uniprot id: G0GFQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

869211:SPITH RS05915
gene id: 869211:SPITH_RS05915
uniprot id: G0GE83
names: Similarity
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.

869211:SPITH RS05820
gene id: 869211:SPITH_RS05820
uniprot id: G0GE64
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

869211:SPITH RS03420
gene id: 869211:SPITH_RS03420
uniprot id: G0GAB0
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

869211:SPITH RS07125
gene id: 869211:SPITH_RS07125
uniprot id: G0GFX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

869211:SPITH RS04455
gene id: 869211:SPITH_RS04455
uniprot id: G0GBS2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

869211:SPITH RS05835
gene id: 869211:SPITH_RS05835
uniprot id: G0GE67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

869211:SPITH RS00555
gene id: 869211:SPITH_RS00555
uniprot id: G0GC35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

869211:SPITH RS01355
gene id: 869211:SPITH_RS01355
uniprot id: G0GDC9
names: Similarity
messages: Belongs to the peptidase M20B family.

869211:SPITH RS01390
gene id: 869211:SPITH_RS01390
uniprot id: G0GDD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

869211:SPITH RS06525
gene id: 869211:SPITH_RS06525
uniprot id: G0GFD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

869211:SPITH RS02545
gene id: 869211:SPITH_RS02545
uniprot id: G0GF84
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

869211:SPITH RS10925
gene id: 869211:SPITH_RS10925
uniprot id: G0GFJ9
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS08520
gene id: 869211:SPITH_RS08520
uniprot id: G0GBC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

869211:SPITH RS10755
gene id: 869211:SPITH_RS10755
uniprot id: G0GF22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

869211:SPITH RS10765
gene id: 869211:SPITH_RS10765
uniprot id: G0GF24
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

869211:SPITH RS07605
gene id: 869211:SPITH_RS07605
uniprot id: G0GAD2
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS05465
gene id: 869211:SPITH_RS05465
uniprot id: G0GDJ9
names: Subcellular Location Annotation
messages: Nucleus

869211:SPITH RS02115
gene id: 869211:SPITH_RS02115
uniprot id: G0GEL5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS00870
gene id: 869211:SPITH_RS00870
uniprot id: G0GCP1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

869211:SPITH RS07865
gene id: 869211:SPITH_RS07865
uniprot id: G0GAI1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS06035
gene id: 869211:SPITH_RS06035
uniprot id: G0GEQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

869211:SPITH RS01565
gene id: 869211:SPITH_RS01565
uniprot id: G0GDW6
names: Similarity
messages: Belongs to the FemABX family.

869211:SPITH RS06445
gene id: 869211:SPITH_RS06445
uniprot id: G0GFB7
names: Similarity
messages: Belongs to the alkaline phosphatase family.

869211:SPITH RS08810
gene id: 869211:SPITH_RS08810
uniprot id: G0GBX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

869211:SPITH RS08690
gene id: 869211:SPITH_RS08690
uniprot id: G0GBV4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

869211:SPITH RS05900
gene id: 869211:SPITH_RS05900
uniprot id: G0GE80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

869211:SPITH RS02530
gene id: 869211:SPITH_RS02530
uniprot id: G0GF81
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

869211:SPITH RS05175
gene id: 869211:SPITH_RS05175
uniprot id: G0GCZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

869211:SPITH RS01680
gene id: 869211:SPITH_RS01680
uniprot id: G0GDY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

869211:SPITH RS10105
gene id: 869211:SPITH_RS10105
uniprot id: G0GEA4
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS09915
gene id: 869211:SPITH_RS09915
uniprot id: G0GDS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS09860
gene id: 869211:SPITH_RS09860
uniprot id: G0GDR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS11720
gene id: 869211:SPITH_RS11720
uniprot id: G0GG75
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

869211:SPITH RS00835
gene id: 869211:SPITH_RS00835
uniprot id: G0GCN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS01175
gene id: 869211:SPITH_RS01175
uniprot id: G0GCV1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

869211:SPITH RS09795
gene id: 869211:SPITH_RS09795
uniprot id: G0GDP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

869211:SPITH RS08595
gene id: 869211:SPITH_RS08595
uniprot id: G0GBD7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

869211:SPITH RS02140
gene id: 869211:SPITH_RS02140
uniprot id: G0GEM0
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS00495
gene id: 869211:SPITH_RS00495
uniprot id: G0GC23
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS07810
gene id: 869211:SPITH_RS07810
uniprot id: G0GAH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS06090
gene id: 869211:SPITH_RS06090
uniprot id: G0GER2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

869211:SPITH RS07510
gene id: 869211:SPITH_RS07510
uniprot id: G0GA46
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

869211:SPITH RS10375
gene id: 869211:SPITH_RS10375
uniprot id: G0GEF8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

869211:SPITH RS10070
gene id: 869211:SPITH_RS10070
uniprot id: G0GDV4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

869211:SPITH RS01775
gene id: 869211:SPITH_RS01775
uniprot id: G0GE06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS09495
gene id: 869211:SPITH_RS09495
uniprot id: G0GD42
names: Similarity
messages: Belongs to the transglycosylase Slt family.

869211:SPITH RS09760
gene id: 869211:SPITH_RS09760
uniprot id: G0GDP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

869211:SPITH RS08430
gene id: 869211:SPITH_RS08430
uniprot id: G0GBA4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

869211:SPITH RS00550
gene id: 869211:SPITH_RS00550
uniprot id: G0GC34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

869211:SPITH RS11780
gene id: 869211:SPITH_RS11780
uniprot id: G0GES6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

869211:SPITH RS06640
gene id: 869211:SPITH_RS06640
uniprot id: G0GFF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

869211:SPITH RS01050
gene id: 869211:SPITH_RS01050
uniprot id: G0GCS7
names: Similarity
messages: Belongs to the RutC family.

869211:SPITH RS02700
gene id: 869211:SPITH_RS02700
uniprot id: G0G9R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

869211:SPITH RS11400
gene id: 869211:SPITH_RS11400
uniprot id: G0GG15
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS08495
gene id: 869211:SPITH_RS08495
uniprot id: G0GBB7
names: Similarity
messages: Belongs to the MEMO1 family.

869211:SPITH RS05365
gene id: 869211:SPITH_RS05365
uniprot id: G0GDI0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

869211:SPITH RS08165
gene id: 869211:SPITH_RS08165
uniprot id: G0GAW2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

869211:SPITH RS06295
gene id: 869211:SPITH_RS06295
uniprot id: G0GEU7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

869211:SPITH RS02560
gene id: 869211:SPITH_RS02560
uniprot id: G0GF86
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

869211:SPITH RS02885
gene id: 869211:SPITH_RS02885
uniprot id: G0G9V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

869211:SPITH RS02685
gene id: 869211:SPITH_RS02685
uniprot id: G0GFB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

869211:SPITH RS10340
gene id: 869211:SPITH_RS10340
uniprot id: G0GEF1
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS10240
gene id: 869211:SPITH_RS10240
uniprot id: G0GED1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

869211:SPITH RS07555
gene id: 869211:SPITH_RS07555
uniprot id: G0GAC2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

869211:SPITH RS05805
gene id: 869211:SPITH_RS05805
uniprot id: G0GE61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

869211:SPITH RS04535
gene id: 869211:SPITH_RS04535
uniprot id: G0GBT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

869211:SPITH RS06925
gene id: 869211:SPITH_RS06925
uniprot id: G0GFT4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

869211:SPITH RS09755
gene id: 869211:SPITH_RS09755
uniprot id: G0GDP1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

869211:SPITH RS02345
gene id: 869211:SPITH_RS02345
uniprot id: G0GF48
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

869211:SPITH RS09215
gene id: 869211:SPITH_RS09215
uniprot id: G0GCJ7
names: Similarity
messages: Belongs to the NDK family.

869211:SPITH RS08695
gene id: 869211:SPITH_RS08695
uniprot id: G0GBV5
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS00735
gene id: 869211:SPITH_RS00735
uniprot id: G0GC71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

869211:SPITH RS05950
gene id: 869211:SPITH_RS05950
uniprot id: G0GE90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

869211:SPITH RS10100
gene id: 869211:SPITH_RS10100
uniprot id: G0GDW0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

869211:SPITH RS09955
gene id: 869211:SPITH_RS09955
uniprot id: G0GDT1
names: Similarity
messages: Belongs to the leucine-binding protein family.

869211:SPITH RS06940
gene id: 869211:SPITH_RS06940
uniprot id: G0GFT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

869211:SPITH RS10740
gene id: 869211:SPITH_RS10740
uniprot id: G0GF19
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

869211:SPITH RS04765
gene id: 869211:SPITH_RS04765
uniprot id: G0GCC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

869211:SPITH RS05630
gene id: 869211:SPITH_RS05630
uniprot id: G0GDN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

869211:SPITH RS00965
gene id: 869211:SPITH_RS00965
uniprot id: G0GCR0
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS05195
gene id: 869211:SPITH_RS05195
uniprot id: G0GD01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

869211:SPITH RS01200
gene id: 869211:SPITH_RS01200
uniprot id: G0GD98
names: Similarity
messages: Belongs to the aldose epimerase family.

869211:SPITH RS01320
gene id: 869211:SPITH_RS01320
uniprot id: G0GDC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

869211:SPITH RS10360
gene id: 869211:SPITH_RS10360
uniprot id: G0GEF5
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS05470
gene id: 869211:SPITH_RS05470
uniprot id: G0GDK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

869211:SPITH RS08900
gene id: 869211:SPITH_RS08900
uniprot id: G0GBZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS03375
gene id: 869211:SPITH_RS03375
uniprot id: G0GAA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS10255
gene id: 869211:SPITH_RS10255
uniprot id: G0GED4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

869211:SPITH RS05905
gene id: 869211:SPITH_RS05905
uniprot id: G0GE81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

869211:SPITH RS04195
gene id: 869211:SPITH_RS04195
uniprot id: G0GB72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

869211:SPITH RS00895
gene id: 869211:SPITH_RS00895
uniprot id: G0GCP6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

869211:SPITH RS04700
gene id: 869211:SPITH_RS04700
uniprot id: G0GCB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

869211:SPITH RS06980
gene id: 869211:SPITH_RS06980
uniprot id: G0GFU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

869211:SPITH RS07050
gene id: 869211:SPITH_RS07050
uniprot id: G0GFV7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

869211:SPITH RS00100
gene id: 869211:SPITH_RS00100
uniprot id: G0GBE9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS04780
gene id: 869211:SPITH_RS04780
uniprot id: G0GCC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

869211:SPITH RS04355
gene id: 869211:SPITH_RS04355
uniprot id: G0GBQ2
names: Similarity
messages: Belongs to the TlyA family.

869211:SPITH RS02590
gene id: 869211:SPITH_RS02590
uniprot id: G0GF91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

869211:SPITH RS10010
gene id: 869211:SPITH_RS10010
uniprot id: G0GDU2
names: Similarity
messages: Belongs to the UPF0045 family.

869211:SPITH RS04740
gene id: 869211:SPITH_RS04740
uniprot id: G0GCC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

869211:SPITH RS04745
gene id: 869211:SPITH_RS04745
uniprot id: G0GCC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

869211:SPITH RS02775
gene id: 869211:SPITH_RS02775
uniprot id: G0G9S8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

869211:SPITH RS10910
gene id: 869211:SPITH_RS10910
uniprot id: G0GFJ6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

869211:SPITH RS05775
gene id: 869211:SPITH_RS05775
uniprot id: G0GE55
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

869211:SPITH RS03340
gene id: 869211:SPITH_RS03340
uniprot id: G0GA95
names: Similarity
messages: Belongs to the bacterial glucokinase family.

869211:SPITH RS04320
gene id: 869211:SPITH_RS04320
uniprot id: G0GBP5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

869211:SPITH RS00050
gene id: 869211:SPITH_RS00050
uniprot id: G0GAZ6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

869211:SPITH RS09660
gene id: 869211:SPITH_RS09660
uniprot id: G0GD76
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

869211:SPITH RS08740
gene id: 869211:SPITH_RS08740
uniprot id: G0GBW2
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS03635
gene id: 869211:SPITH_RS03635
uniprot id: G0GAM5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

869211:SPITH RS09555
gene id: 869211:SPITH_RS09555
uniprot id: G0GD54
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

869211:SPITH RS06235
gene id: 869211:SPITH_RS06235
uniprot id: G0GET5
names: Similarity
messages: Belongs to the WrbA family.

869211:SPITH RS09385
gene id: 869211:SPITH_RS09385
uniprot id: G0GD22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

869211:SPITH RS07540
gene id: 869211:SPITH_RS07540
uniprot id: G0GAB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

869211:SPITH RS08725
gene id: 869211:SPITH_RS08725
uniprot id: G0GBW1
names: Subcellular Location Annotation
messages: Cell inner membrane

869211:SPITH RS01750
gene id: 869211:SPITH_RS01750
uniprot id: G0GE01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

869211:SPITH RS09090
gene id: 869211:SPITH_RS09090
uniprot id: G0GCH3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

869211:SPITH RS00545
gene id: 869211:SPITH_RS00545
uniprot id: G0GC33
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

869211:SPITH RS03830
gene id: 869211:SPITH_RS03830
uniprot id: G0GB02
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

869211:SPITH RS07285
gene id: 869211:SPITH_RS07285
uniprot id: G0GA04
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

869211:SPITH RS02745
gene id: 869211:SPITH_RS02745
uniprot id: G0G9S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

869211:SPITH RS04945
gene id: 869211:SPITH_RS04945
uniprot id: G0GCV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

869211:SPITH RS04325
gene id: 869211:SPITH_RS04325
uniprot id: G0GBP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

869211:SPITH RS03300
gene id: 869211:SPITH_RS03300
uniprot id: G0GA87
names: Similarity
messages: Belongs to the DtxR/MntR family.

869211:SPITH RS11315
gene id: 869211:SPITH_RS11315
uniprot id: G0GG00
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

869211:SPITH RS11665
gene id: 869211:SPITH_RS11665
uniprot id: G0GG64
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS02190
gene id: 869211:SPITH_RS02190
uniprot id: G0GEN0
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

869211:SPITH RS10465
gene id: 869211:SPITH_RS10465
uniprot id: G0GEH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS00030
gene id: 869211:SPITH_RS00030
uniprot id: G0GAZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

869211:SPITH RS06635
gene id: 869211:SPITH_RS06635
uniprot id: G0GFF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

869211:SPITH RS04815
gene id: 869211:SPITH_RS04815
uniprot id: G0GCD5
names: Similarity
messages: Belongs to the MotB family.

869211:SPITH RS06100
gene id: 869211:SPITH_RS06100
uniprot id: G0GER4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS10065
gene id: 869211:SPITH_RS10065
uniprot id: G0GDV3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

869211:SPITH RS04825
gene id: 869211:SPITH_RS04825
uniprot id: G0GCD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

869211:SPITH RS03270
gene id: 869211:SPITH_RS03270
uniprot id: G0GA81
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

869211:SPITH RS06560
gene id: 869211:SPITH_RS06560
uniprot id: G0GFE1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

869211:SPITH RS06770
gene id: 869211:SPITH_RS06770
uniprot id: G0GFI2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

869211:SPITH RS10080
gene id: 869211:SPITH_RS10080
uniprot id: G0GDV6
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS06590
gene id: 869211:SPITH_RS06590
uniprot id: G0GFE7
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

869211:SPITH RS02490
gene id: 869211:SPITH_RS02490
uniprot id: G0GF73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS01640
gene id: 869211:SPITH_RS01640
uniprot id: G0GDY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

869211:SPITH RS00035
gene id: 869211:SPITH_RS00035
uniprot id: G0GAZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

869211:SPITH RS03400
gene id: 869211:SPITH_RS03400
uniprot id: G0GAA6
names: Similarity
messages: Belongs to the glutamate synthase family.

869211:SPITH RS03135
gene id: 869211:SPITH_RS03135
uniprot id: G0GA54
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

869211:SPITH RS04260
gene id: 869211:SPITH_RS04260
uniprot id: G0GBN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

869211:SPITH RS10075
gene id: 869211:SPITH_RS10075
uniprot id: G0GDV5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

869211:SPITH RS02680
gene id: 869211:SPITH_RS02680
uniprot id: G0GFA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

869211:SPITH RS00060
gene id: 869211:SPITH_RS00060
uniprot id: G0GAZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

869211:SPITH RS05010
gene id: 869211:SPITH_RS05010
uniprot id: G0GCW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

869211:SPITH RS08660
gene id: 869211:SPITH_RS08660
uniprot id: G0GBU8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

869211:SPITH RS10420
gene id: 869211:SPITH_RS10420
uniprot id: G0GEG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

869211:SPITH RS01120
gene id: 869211:SPITH_RS01120
uniprot id: G0GCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

869211:SPITH RS07835
gene id: 869211:SPITH_RS07835
uniprot id: G0GAH5
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

869211:SPITH RS08805
gene id: 869211:SPITH_RS08805
uniprot id: G0GBX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

869211:SPITH RS11715
gene id: 869211:SPITH_RS11715
uniprot id: G0GG74
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

869211:SPITH RS00425
gene id: 869211:SPITH_RS00425
uniprot id: G0GBL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

869211:SPITH RS09540
gene id: 869211:SPITH_RS09540
uniprot id: G0GD51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS01230
gene id: 869211:SPITH_RS01230
uniprot id: G0GDA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS02845
gene id: 869211:SPITH_RS02845
uniprot id: G0G9U2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS03915
gene id: 869211:SPITH_RS03915
uniprot id: G0GB18
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

869211:SPITH RS09405
gene id: 869211:SPITH_RS09405
uniprot id: G0GD26
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS05375
gene id: 869211:SPITH_RS05375
uniprot id: G0GDI2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

869211:SPITH RS02660
gene id: 869211:SPITH_RS02660
uniprot id: G0GFA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

869211:SPITH RS04390
gene id: 869211:SPITH_RS04390
uniprot id: G0GBQ9
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS10920
gene id: 869211:SPITH_RS10920
uniprot id: G0GFJ8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

869211:SPITH RS02945
gene id: 869211:SPITH_RS02945
uniprot id: G0G9V9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

869211:SPITH RS02600
gene id: 869211:SPITH_RS02600
uniprot id: G0GF93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

869211:SPITH RS01130
gene id: 869211:SPITH_RS01130
uniprot id: G0GCU2
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

869211:SPITH RS11220
gene id: 869211:SPITH_RS11220
uniprot id: G0GFY0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

869211:SPITH RS05300
gene id: 869211:SPITH_RS05300
uniprot id: G0GDG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS10970
gene id: 869211:SPITH_RS10970
uniprot id: G0GFK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

869211:SPITH RS02835
gene id: 869211:SPITH_RS02835
uniprot id: G0G9U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

869211:SPITH RS04130
gene id: 869211:SPITH_RS04130
uniprot id: G0GB59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

869211:SPITH RS05155
gene id: 869211:SPITH_RS05155
uniprot id: G0GCZ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

869211:SPITH RS11275
gene id: 869211:SPITH_RS11275
uniprot id: G0GFZ2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

869211:SPITH RS09610
gene id: 869211:SPITH_RS09610
uniprot id: G0GD66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

869211:SPITH RS05755
gene id: 869211:SPITH_RS05755
uniprot id: G0GE51
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

869211:SPITH RS00605
gene id: 869211:SPITH_RS00605
uniprot id: G0GC45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

869211:SPITH RS04440
gene id: 869211:SPITH_RS04440
uniprot id: G0GBR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

869211:SPITH RS00055
gene id: 869211:SPITH_RS00055
uniprot id: G0GAZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

869211:SPITH RS08475
gene id: 869211:SPITH_RS08475
uniprot id: G0GBB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

869211:SPITH RS11520
gene id: 869211:SPITH_RS11520
uniprot id: G0GG40
names: Similarity
messages: Belongs to the band 7/mec-2 family.

869211:SPITH RS10450
gene id: 869211:SPITH_RS10450
uniprot id: G0GEH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

869211:SPITH RS05890
gene id: 869211:SPITH_RS05890
uniprot id: G0GE78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

869211:SPITH RS00980
gene id: 869211:SPITH_RS00980
uniprot id: G0GCR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

869211:SPITH RS09945
gene id: 869211:SPITH_RS09945
uniprot id: G0GDS9
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS10130
gene id: 869211:SPITH_RS10130
uniprot id: G0GEA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

869211:SPITH RS06895
gene id: 869211:SPITH_RS06895
uniprot id: G0GFS8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

869211:SPITH RS08330
gene id: 869211:SPITH_RS08330
uniprot id: G0GB84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

869211:SPITH RS01035
gene id: 869211:SPITH_RS01035
uniprot id: G0GCS4
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS10290
gene id: 869211:SPITH_RS10290
uniprot id: G0GEE1
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS00690
gene id: 869211:SPITH_RS00690
uniprot id: G0GC62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

869211:SPITH RS09245
gene id: 869211:SPITH_RS09245
uniprot id: G0GCK3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

869211:SPITH RS06070
gene id: 869211:SPITH_RS06070
uniprot id: G0GEQ8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

869211:SPITH RS04850
gene id: 869211:SPITH_RS04850
uniprot id: G0GCE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

869211:SPITH RS04515
gene id: 869211:SPITH_RS04515
uniprot id: G0GBT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

869211:SPITH RS04840
gene id: 869211:SPITH_RS04840
uniprot id: G0GCE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

869211:SPITH RS11015
gene id: 869211:SPITH_RS11015
uniprot id: G0GFL7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

869211:SPITH RS02040
gene id: 869211:SPITH_RS02040
uniprot id: G0GEK0
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

869211:SPITH RS11605
gene id: 869211:SPITH_RS11605
uniprot id: G0GG57
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

869211:SPITH RS02640
gene id: 869211:SPITH_RS02640
uniprot id: G0GFA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

869211:SPITH RS06880
gene id: 869211:SPITH_RS06880
uniprot id: G0GFS5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

869211:SPITH RS08490
gene id: 869211:SPITH_RS08490
uniprot id: G0GBB6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

869211:SPITH RS03645
gene id: 869211:SPITH_RS03645
uniprot id: G0GAM7
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

869211:SPITH RS05965
gene id: 869211:SPITH_RS05965
uniprot id: G0GE94
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS02005
gene id: 869211:SPITH_RS02005
uniprot id: G0GEJ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

869211:SPITH RS04435
gene id: 869211:SPITH_RS04435
uniprot id: G0GBR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

869211:SPITH RS05560
gene id: 869211:SPITH_RS05560
uniprot id: G0GDL9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

869211:SPITH RS00015
gene id: 869211:SPITH_RS00015
uniprot id: G0GAY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

869211:SPITH RS09285
gene id: 869211:SPITH_RS09285
uniprot id: G0GCL1
names: Similarity
messages: Belongs to the UPF0178 family.

869211:SPITH RS00365
gene id: 869211:SPITH_RS00365
uniprot id: G0GBK2
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

869211:SPITH RS04905
gene id: 869211:SPITH_RS04905
uniprot id: G0GCF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

869211:SPITH RS09170
gene id: 869211:SPITH_RS09170
uniprot id: G0GCI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

869211:SPITH RS00080
gene id: 869211:SPITH_RS00080
uniprot id: G0GBE5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

869211:SPITH RS04680
gene id: 869211:SPITH_RS04680
uniprot id: G0GCA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

869211:SPITH RS05440
gene id: 869211:SPITH_RS05440
uniprot id: G0GDJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

869211:SPITH RS06715
gene id: 869211:SPITH_RS06715
uniprot id: G0GFH2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

869211:SPITH RS02275
gene id: 869211:SPITH_RS02275
uniprot id: G0GEP6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

869211:SPITH RS06745
gene id: 869211:SPITH_RS06745
uniprot id: G0GFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS10470
gene id: 869211:SPITH_RS10470
uniprot id: G0GEH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

869211:SPITH RS00785
gene id: 869211:SPITH_RS00785
uniprot id: G0GC81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS00170
gene id: 869211:SPITH_RS00170
uniprot id: G0GBG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

869211:SPITH RS10200
gene id: 869211:SPITH_RS10200
uniprot id: G0GEC3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

869211:SPITH RS02715
gene id: 869211:SPITH_RS02715
uniprot id: G0G9R6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

869211:SPITH RS09450
gene id: 869211:SPITH_RS09450
uniprot id: G0GD35
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

869211:SPITH RS11145
gene id: 869211:SPITH_RS11145
uniprot id: G0GFP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

869211:SPITH RS00685
gene id: 869211:SPITH_RS00685
uniprot id: G0GC61
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS02480
gene id: 869211:SPITH_RS02480
uniprot id: G0GF71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS10565
gene id: 869211:SPITH_RS10565
uniprot id: G0GEY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

869211:SPITH RS05310
gene id: 869211:SPITH_RS05310
uniprot id: G0GDG9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

869211:SPITH RS07115
gene id: 869211:SPITH_RS07115
uniprot id: G0GFX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

869211:SPITH RS01810
gene id: 869211:SPITH_RS01810
uniprot id: G0GE13
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

869211:SPITH RS07665
gene id: 869211:SPITH_RS07665
uniprot id: G0GAE4
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS01770
gene id: 869211:SPITH_RS01770
uniprot id: G0GE05
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS05410
gene id: 869211:SPITH_RS05410
uniprot id: G0GDI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

869211:SPITH RS08530
gene id: 869211:SPITH_RS08530
uniprot id: G0GBC4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

869211:SPITH RS10820
gene id: 869211:SPITH_RS10820
uniprot id: G0GF33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

869211:SPITH RS10640
gene id: 869211:SPITH_RS10640
uniprot id: G0GF02
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

869211:SPITH RS01755
gene id: 869211:SPITH_RS01755
uniprot id: G0GE02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

869211:SPITH RS06570
gene id: 869211:SPITH_RS06570
uniprot id: G0GFE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

869211:SPITH RS00680
gene id: 869211:SPITH_RS00680
uniprot id: G0GC60
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

869211:SPITH RS00045
gene id: 869211:SPITH_RS00045
uniprot id: G0GAZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

869211:SPITH RS01495
gene id: 869211:SPITH_RS01495
uniprot id: G0GDF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

869211:SPITH RS11100
gene id: 869211:SPITH_RS11100
uniprot id: G0GFN4
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS02070
gene id: 869211:SPITH_RS02070
uniprot id: G0GEK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

869211:SPITH RS02670
gene id: 869211:SPITH_RS02670
uniprot id: G0GFA7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

869211:SPITH RS08275
gene id: 869211:SPITH_RS08275
uniprot id: G0GB73
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS02105
gene id: 869211:SPITH_RS02105
uniprot id: G0GEL3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

869211:SPITH RS11515
gene id: 869211:SPITH_RS11515
uniprot id: G0GG39
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS03760
gene id: 869211:SPITH_RS03760
uniprot id: G0GAP7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

869211:SPITH RS11585
gene id: 869211:SPITH_RS11585
uniprot id: G0GG53
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

869211:SPITH RS11345
gene id: 869211:SPITH_RS11345
uniprot id: G0GG06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

869211:SPITH RS06630
gene id: 869211:SPITH_RS06630
uniprot id: G0GFF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

869211:SPITH RS03595
gene id: 869211:SPITH_RS03595
uniprot id: G0GAL7
names: Similarity
messages: Belongs to the UPF0251 family.

869211:SPITH RS06730
gene id: 869211:SPITH_RS06730
uniprot id: G0GFH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS10590
gene id: 869211:SPITH_RS10590
uniprot id: E6JTG4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

869211:SPITH RS05430
gene id: 869211:SPITH_RS05430
uniprot id: G0GDJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

869211:SPITH RS07725
gene id: 869211:SPITH_RS07725
uniprot id: G0GAF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

869211:SPITH RS09325
gene id: 869211:SPITH_RS09325
uniprot id: G0GCL9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

869211:SPITH RS04910
gene id: 869211:SPITH_RS04910
uniprot id: G0GCF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

869211:SPITH RS05675
gene id: 869211:SPITH_RS05675
uniprot id: G0GE36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

869211:SPITH RS10935
gene id: 869211:SPITH_RS10935
uniprot id: G0GFK1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

869211:SPITH RS10830
gene id: 869211:SPITH_RS10830
uniprot id: G0GF35
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

869211:SPITH RS06415
gene id: 869211:SPITH_RS06415
uniprot id: G0GEW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

869211:SPITH RS08895
gene id: 869211:SPITH_RS08895
uniprot id: G0GBZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS02950
gene id: 869211:SPITH_RS02950
uniprot id: G0G9W0
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

869211:SPITH RS04080
gene id: 869211:SPITH_RS04080
uniprot id: G0GB51
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

869211:SPITH RS09840
gene id: 869211:SPITH_RS09840
uniprot id: G0GDQ8
names: Similarity
messages: Belongs to the Fur family.

869211:SPITH RS02705
gene id: 869211:SPITH_RS02705
uniprot id: G0G9R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

869211:SPITH RS02435
gene id: 869211:SPITH_RS02435
uniprot id: G0GF62
names: Similarity
messages: Belongs to the histone deacetylase family.

869211:SPITH RS04725
gene id: 869211:SPITH_RS04725
uniprot id: G0GCB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

869211:SPITH RS10350
gene id: 869211:SPITH_RS10350
uniprot id: G0GEF3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

869211:SPITH RS11195
gene id: 869211:SPITH_RS11195
uniprot id: G0GFQ2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

869211:SPITH RS00225
gene id: 869211:SPITH_RS00225
uniprot id: G0GBH4
names: Similarity
messages: Belongs to the PspA/IM30 family.

869211:SPITH RS11055
gene id: 869211:SPITH_RS11055
uniprot id: G0GFM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

869211:SPITH RS06495
gene id: 869211:SPITH_RS06495
uniprot id: G0GFC8
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS02625
gene id: 869211:SPITH_RS02625
uniprot id: G0GF98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

869211:SPITH RS08755
gene id: 869211:SPITH_RS08755
uniprot id: G0GBW5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

869211:SPITH RS05355
gene id: 869211:SPITH_RS05355
uniprot id: G0GDH8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

869211:SPITH RS05795
gene id: 869211:SPITH_RS05795
uniprot id: G0GE59
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS01835
gene id: 869211:SPITH_RS01835
uniprot id: G0GE18
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

869211:SPITH RS08840
gene id: 869211:SPITH_RS08840
uniprot id: G0GBY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

869211:SPITH RS09885
gene id: 869211:SPITH_RS09885
uniprot id: G0GDR7
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

869211:SPITH RS05550
gene id: 869211:SPITH_RS05550
uniprot id: G0GDL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

869211:SPITH RS07165
gene id: 869211:SPITH_RS07165
uniprot id: G0G9Y5
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

869211:SPITH RS07855
gene id: 869211:SPITH_RS07855
uniprot id: G0GAH9
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

869211:SPITH RS02025
gene id: 869211:SPITH_RS02025
uniprot id: G0GEJ7
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

869211:SPITH RS10385
gene id: 869211:SPITH_RS10385
uniprot id: G0GEG0
names: Similarity
messages: Belongs to the CinA family.

869211:SPITH RS02570
gene id: 869211:SPITH_RS02570
uniprot id: G0GF87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

869211:SPITH RS03965
gene id: 869211:SPITH_RS03965
uniprot id: G0GB28
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS07580
gene id: 869211:SPITH_RS07580
uniprot id: G0GAC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

869211:SPITH RS09705
gene id: 869211:SPITH_RS09705
uniprot id: G0GD85
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

869211:SPITH RS03980
gene id: 869211:SPITH_RS03980
uniprot id: G0GB31
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

869211:SPITH RS04560
gene id: 869211:SPITH_RS04560
uniprot id: G0GC86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

869211:SPITH RS04500
gene id: 869211:SPITH_RS04500
uniprot id: G0GBT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

869211:SPITH RS00400
gene id: 869211:SPITH_RS00400
uniprot id: G0GBK9
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

869211:SPITH RS10220
gene id: 869211:SPITH_RS10220
uniprot id: G0GEC7
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS09370
gene id: 869211:SPITH_RS09370
uniprot id: G0GCM8
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

869211:SPITH RS00380
gene id: 869211:SPITH_RS00380
uniprot id: G0GBK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS02520
gene id: 869211:SPITH_RS02520
uniprot id: G0GF79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

869211:SPITH RS07265
gene id: 869211:SPITH_RS07265
uniprot id: G0GA00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

869211:SPITH RS02695
gene id: 869211:SPITH_RS02695
uniprot id: G0G9R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

869211:SPITH RS08610
gene id: 869211:SPITH_RS08610
uniprot id: G0GBE0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

869211:SPITH RS03770
gene id: 869211:SPITH_RS03770
uniprot id: G0GAP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

869211:SPITH RS11850
gene id: 869211:SPITH_RS11850
uniprot id: G0GF18
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

869211:SPITH RS06750
gene id: 869211:SPITH_RS06750
uniprot id: G0GFH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS07245
gene id: 869211:SPITH_RS07245
uniprot id: G0G9Z8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

869211:SPITH RS02740
gene id: 869211:SPITH_RS02740
uniprot id: G0G9S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

869211:SPITH RS06120
gene id: 869211:SPITH_RS06120
uniprot id: G0GER8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

869211:SPITH RS02110
gene id: 869211:SPITH_RS02110
uniprot id: G0GEL4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

869211:SPITH RS10875
gene id: 869211:SPITH_RS10875
uniprot id: G0GFI9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

869211:SPITH RS07085
gene id: 869211:SPITH_RS07085
uniprot id: G0GFW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

869211:SPITH RS05230
gene id: 869211:SPITH_RS05230
uniprot id: G0GD08
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

869211:SPITH RS06080
gene id: 869211:SPITH_RS06080
uniprot id: G0GER0
names: Similarity
messages: Belongs to the citrate synthase family.

869211:SPITH RS08365
gene id: 869211:SPITH_RS08365
uniprot id: G0GB91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

869211:SPITH RS02595
gene id: 869211:SPITH_RS02595
uniprot id: G0GF92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

869211:SPITH RS06575
gene id: 869211:SPITH_RS06575
uniprot id: G0GFE4
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS02575
gene id: 869211:SPITH_RS02575
uniprot id: G0GF88
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

869211:SPITH RS10715
gene id: 869211:SPITH_RS10715
uniprot id: G0GF17
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

869211:SPITH RS03785
gene id: 869211:SPITH_RS03785
uniprot id: G0GAQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

869211:SPITH RS10835
gene id: 869211:SPITH_RS10835
uniprot id: G0GF36
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

869211:SPITH RS10445
gene id: 869211:SPITH_RS10445
uniprot id: G0GEH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

869211:SPITH RS07035
gene id: 869211:SPITH_RS07035
uniprot id: G0GFV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

869211:SPITH RS07610
gene id: 869211:SPITH_RS07610
uniprot id: G0GAD3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

869211:SPITH RS11390
gene id: 869211:SPITH_RS11390
uniprot id: G0GG13
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

869211:SPITH RS02605
gene id: 869211:SPITH_RS02605
uniprot id: G0GF94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

869211:SPITH RS04615
gene id: 869211:SPITH_RS04615
uniprot id: G0GC95
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

869211:SPITH RS05745
gene id: 869211:SPITH_RS05745
uniprot id: G0GE49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

869211:SPITH RS05330
gene id: 869211:SPITH_RS05330
uniprot id: G0GDH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

869211:SPITH RS04685
gene id: 869211:SPITH_RS04685
uniprot id: G0GCA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

869211:SPITH RS01095
gene id: 869211:SPITH_RS01095
uniprot id: G0GCT5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

869211:SPITH RS02585
gene id: 869211:SPITH_RS02585
uniprot id: G0GF90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

869211:SPITH RS10785
gene id: 869211:SPITH_RS10785
uniprot id: G0GF28
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

869211:SPITH RS00455
gene id: 869211:SPITH_RS00455
uniprot id: G0GC15
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

869211:SPITH RS04150
gene id: 869211:SPITH_RS04150
uniprot id: G0GB63
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS11555
gene id: 869211:SPITH_RS11555
uniprot id: G0GG47
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

869211:SPITH RS11430
gene id: 869211:SPITH_RS11430
uniprot id: G0GG21
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

869211:SPITH RS00715
gene id: 869211:SPITH_RS00715
uniprot id: G0GC67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

869211:SPITH RS10650
gene id: 869211:SPITH_RS10650
uniprot id: G0GF04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

869211:SPITH RS06350
gene id: 869211:SPITH_RS06350
uniprot id: G0GEV7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

869211:SPITH RS11525
gene id: 869211:SPITH_RS11525
uniprot id: G0GG41
names: Similarity
messages: Belongs to the band 7/mec-2 family.

869211:SPITH RS03410
gene id: 869211:SPITH_RS03410
uniprot id: G0GAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

869211:SPITH RS03565
gene id: 869211:SPITH_RS03565
uniprot id: G0GAL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

869211:SPITH RS09855
gene id: 869211:SPITH_RS09855
uniprot id: G0GDR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS05395
gene id: 869211:SPITH_RS05395
uniprot id: E6JTG4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

869211:SPITH RS03280
gene id: 869211:SPITH_RS03280
uniprot id: G0GA83
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

869211:SPITH RS04830
gene id: 869211:SPITH_RS04830
uniprot id: G0GCD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

869211:SPITH RS03680
gene id: 869211:SPITH_RS03680
uniprot id: G0GAN4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

869211:SPITH RS09685
gene id: 869211:SPITH_RS09685
uniprot id: G0GD81
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

869211:SPITH RS02015
gene id: 869211:SPITH_RS02015
uniprot id: G0GEJ5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

869211:SPITH RS01385
gene id: 869211:SPITH_RS01385
uniprot id: G0GDD5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS08785
gene id: 869211:SPITH_RS08785
uniprot id: G0GBX1
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

869211:SPITH RS01205
gene id: 869211:SPITH_RS01205
uniprot id: G0GD99
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

869211:SPITH RS09210
gene id: 869211:SPITH_RS09210
uniprot id: G0GCJ6
names: Similarity
messages: Belongs to the acetyltransferase family. ArgA subfamily.

869211:SPITH RS12155
gene id: 869211:SPITH_RS12155
uniprot id: G0GFK4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

869211:SPITH RS09900
gene id: 869211:SPITH_RS09900
uniprot id: G0GDS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

869211:SPITH RS07200
gene id: 869211:SPITH_RS07200
uniprot id: G0G9Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

869211:SPITH RS00590
gene id: 869211:SPITH_RS00590
uniprot id: G0GC42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

869211:SPITH RS01670
gene id: 869211:SPITH_RS01670
uniprot id: G0GDY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS05265
gene id: 869211:SPITH_RS05265
uniprot id: G0GD15
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS10995
gene id: 869211:SPITH_RS10995
uniprot id: G0GFL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

869211:SPITH RS04845
gene id: 869211:SPITH_RS04845
uniprot id: G0GCE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

869211:SPITH RS04330
gene id: 869211:SPITH_RS04330
uniprot id: G0GBP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

869211:SPITH RS04600
gene id: 869211:SPITH_RS04600
uniprot id: G0GC92
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

869211:SPITH RS05280
gene id: 869211:SPITH_RS05280
uniprot id: G0GD18
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

869211:SPITH RS06990
gene id: 869211:SPITH_RS06990
uniprot id: G0GFU6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

869211:SPITH RS11455
gene id: 869211:SPITH_RS11455
uniprot id: G0GG26
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

869211:SPITH RS05895
gene id: 869211:SPITH_RS05895
uniprot id: G0GE79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

869211:SPITH RS07415
gene id: 869211:SPITH_RS07415
uniprot id: G0GA28
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

869211:SPITH RS00005
gene id: 869211:SPITH_RS00005
uniprot id: G0GAY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

869211:SPITH RS03890
gene id: 869211:SPITH_RS03890
uniprot id: G0GB13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS11610
gene id: 869211:SPITH_RS11610
uniprot id: G0GG58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

869211:SPITH RS04345
gene id: 869211:SPITH_RS04345
uniprot id: G0GBQ0
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

869211:SPITH RS07150
gene id: 869211:SPITH_RS07150
uniprot id: G0GFX7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

869211:SPITH RS03275
gene id: 869211:SPITH_RS03275
uniprot id: G0GA82
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

869211:SPITH RS09530
gene id: 869211:SPITH_RS09530
uniprot id: G0GD49
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

869211:SPITH RS05860
gene id: 869211:SPITH_RS05860
uniprot id: G0GE72
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

869211:SPITH RS05380
gene id: 869211:SPITH_RS05380
uniprot id: G0GDI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

869211:SPITH RS06805
gene id: 869211:SPITH_RS06805
uniprot id: G0GFR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

869211:SPITH RS09025
gene id: 869211:SPITH_RS09025
uniprot id: G0GCG0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

869211:SPITH RS06875
gene id: 869211:SPITH_RS06875
uniprot id: G0GFS4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

869211:SPITH RS11320
gene id: 869211:SPITH_RS11320
uniprot id: G0GG01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

869211:SPITH RS02620
gene id: 869211:SPITH_RS02620
uniprot id: G0GF97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

869211:SPITH RS03525
gene id: 869211:SPITH_RS03525
uniprot id: G0GAK2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

869211:SPITH RS11535
gene id: 869211:SPITH_RS11535
uniprot id: G0GG43
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

869211:SPITH RS07140
gene id: 869211:SPITH_RS07140
uniprot id: G0GFX5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

869211:SPITH RS07410
gene id: 869211:SPITH_RS07410
uniprot id: G0GA27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS09135
gene id: 869211:SPITH_RS09135
uniprot id: G0GCI2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

869211:SPITH RS01655
gene id: 869211:SPITH_RS01655
uniprot id: G0GDY5
names: Similarity
messages: Belongs to the UPF0047 family.

869211:SPITH RS04800
gene id: 869211:SPITH_RS04800
uniprot id: G0GCD2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

869211:SPITH RS04280
gene id: 869211:SPITH_RS04280
uniprot id: G0GBN6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

869211:SPITH RS02690
gene id: 869211:SPITH_RS02690
uniprot id: G0GFB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

869211:SPITH RS02090
gene id: 869211:SPITH_RS02090
uniprot id: G0GEL0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

869211:SPITH RS04365
gene id: 869211:SPITH_RS04365
uniprot id: G0GBQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

869211:SPITH RS08280
gene id: 869211:SPITH_RS08280
uniprot id: G0GB74
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

869211:SPITH RS06515
gene id: 869211:SPITH_RS06515
uniprot id: G0GFD2
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS09490
gene id: 869211:SPITH_RS09490
uniprot id: G0GD41
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

869211:SPITH RS01415
gene id: 869211:SPITH_RS01415
uniprot id: G0GDE1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS02360
gene id: 869211:SPITH_RS02360
uniprot id: G0GF51
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

869211:SPITH RS06335
gene id: 869211:SPITH_RS06335
uniprot id: G0GEV4
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS05660
gene id: 869211:SPITH_RS05660
uniprot id: G0GDN9
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

869211:SPITH RS01795
gene id: 869211:SPITH_RS01795
uniprot id: G0GE10
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

869211:SPITH RS10615
gene id: 869211:SPITH_RS10615
uniprot id: G0GEZ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

869211:SPITH RS00855
gene id: 869211:SPITH_RS00855
uniprot id: G0GCN8
names: Similarity
messages: Belongs to the thioredoxin family.

869211:SPITH RS00120
gene id: 869211:SPITH_RS00120
uniprot id: G0GBF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

869211:SPITH RS06540
gene id: 869211:SPITH_RS06540
uniprot id: G0GFD7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

869211:SPITH RS10325
gene id: 869211:SPITH_RS10325
uniprot id: G0GEE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

869211:SPITH RS04210
gene id: 869211:SPITH_RS04210
uniprot id: G0GBM1
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

869211:SPITH RS07260
gene id: 869211:SPITH_RS07260
uniprot id: G0G9Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

869211:SPITH RS00440
gene id: 869211:SPITH_RS00440
uniprot id: G0GBL7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

869211:SPITH RS04690
gene id: 869211:SPITH_RS04690
uniprot id: G0GCB0
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS05830
gene id: 869211:SPITH_RS05830
uniprot id: G0GE66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

869211:SPITH RS05225
gene id: 869211:SPITH_RS05225
uniprot id: G0GD07
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

869211:SPITH RS01100
gene id: 869211:SPITH_RS01100
uniprot id: G0GCT6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

869211:SPITH RS04415
gene id: 869211:SPITH_RS04415
uniprot id: G0GBR4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

869211:SPITH RS11110
gene id: 869211:SPITH_RS11110
uniprot id: G0GFN6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS09680
gene id: 869211:SPITH_RS09680
uniprot id: G0GD80
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

869211:SPITH RS11235
gene id: 869211:SPITH_RS11235
uniprot id: G0GFY3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

869211:SPITH RS02060
gene id: 869211:SPITH_RS02060
uniprot id: G0GEK4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

869211:SPITH RS07405
gene id: 869211:SPITH_RS07405
uniprot id: G0GA26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS07895
gene id: 869211:SPITH_RS07895
uniprot id: G0GAI7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

869211:SPITH RS09260
gene id: 869211:SPITH_RS09260
uniprot id: G0GCK6
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS03840
gene id: 869211:SPITH_RS03840
uniprot id: G0GB04
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

869211:SPITH RS01265
gene id: 869211:SPITH_RS01265
uniprot id: G0GDB1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

869211:SPITH RS00845
gene id: 869211:SPITH_RS00845
uniprot id: G0GCN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

869211:SPITH RS04125
gene id: 869211:SPITH_RS04125
uniprot id: G0GB58
names: Similarity
messages: Belongs to the Nth/MutY family.

869211:SPITH RS04385
gene id: 869211:SPITH_RS04385
uniprot id: G0GBQ8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

869211:SPITH RS04335
gene id: 869211:SPITH_RS04335
uniprot id: G0GBP8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

869211:SPITH RS02720
gene id: 869211:SPITH_RS02720
uniprot id: G0G9R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

869211:SPITH RS04795
gene id: 869211:SPITH_RS04795
uniprot id: G0GCD1
names: Similarity
messages: Belongs to the FlgD family.

869211:SPITH RS07890
gene id: 869211:SPITH_RS07890
uniprot id: G0GAI6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

869211:SPITH RS05415
gene id: 869211:SPITH_RS05415
uniprot id: G0GDJ0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

869211:SPITH RS09125
gene id: 869211:SPITH_RS09125
uniprot id: G0GCI0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

869211:SPITH RS05115
gene id: 869211:SPITH_RS05115
uniprot id: G0GCY5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

869211:SPITH RS05075
gene id: 869211:SPITH_RS05075
uniprot id: G0GCX7
names: Similarity
messages: Belongs to the LOG family.

869211:SPITH RS00815
gene id: 869211:SPITH_RS00815
uniprot id: G0GC85
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

869211:SPITH RS04135
gene id: 869211:SPITH_RS04135
uniprot id: G0GB60
names: Similarity
messages: Belongs to the phosphohexose mutase family.

869211:SPITH RS05910
gene id: 869211:SPITH_RS05910
uniprot id: G0GE82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

869211:SPITH RS07385
gene id: 869211:SPITH_RS07385
uniprot id: G0GA22
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

869211:SPITH RS04555
gene id: 869211:SPITH_RS04555
uniprot id: G0GBU2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

869211:SPITH RS03895
gene id: 869211:SPITH_RS03895
uniprot id: G0GB14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS06965
gene id: 869211:SPITH_RS06965
uniprot id: G0GFU2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

869211:SPITH RS10570
gene id: 869211:SPITH_RS10570
uniprot id: G0GEY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

869211:SPITH RS03020
gene id: 869211:SPITH_RS03020
uniprot id: G0G9X4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

869211:SPITH RS10225
gene id: 869211:SPITH_RS10225
uniprot id: G0GEC8
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS05530
gene id: 869211:SPITH_RS05530
uniprot id: G0GDL2
names: Similarity
messages: Belongs to the UPF0102 family.

869211:SPITH RS04450
gene id: 869211:SPITH_RS04450
uniprot id: G0GBS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

869211:SPITH RS03560
gene id: 869211:SPITH_RS03560
uniprot id: G0GAL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

869211:SPITH RS08005
gene id: 869211:SPITH_RS08005
uniprot id: G0GAT0
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

869211:SPITH RS00720
gene id: 869211:SPITH_RS00720
uniprot id: G0GC68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS00960
gene id: 869211:SPITH_RS00960
uniprot id: G0GCQ9
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS00390
gene id: 869211:SPITH_RS00390
uniprot id: G0GBK7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

869211:SPITH RS05865
gene id: 869211:SPITH_RS05865
uniprot id: G0GE73
names: Similarity
messages: Belongs to the Skp family.

869211:SPITH RS02515
gene id: 869211:SPITH_RS02515
uniprot id: G0GF78
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

869211:SPITH RS02445
gene id: 869211:SPITH_RS02445
uniprot id: G0GF64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS04920
gene id: 869211:SPITH_RS04920
uniprot id: G0GCF6
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

869211:SPITH RS02675
gene id: 869211:SPITH_RS02675
uniprot id: G0GFA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

869211:SPITH RS00405
gene id: 869211:SPITH_RS00405
uniprot id: G0GBL0
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

869211:SPITH RS00650
gene id: 869211:SPITH_RS00650
uniprot id: G0GC54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

869211:SPITH RS09615
gene id: 869211:SPITH_RS09615
uniprot id: G0GD67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

869211:SPITH RS01575
gene id: 869211:SPITH_RS01575
uniprot id: G0GDW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

869211:SPITH RS09950
gene id: 869211:SPITH_RS09950
uniprot id: G0GDT0
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS00840
gene id: 869211:SPITH_RS00840
uniprot id: G0GCN5
names: Function
names: Similarity
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

869211:SPITH RS03105
gene id: 869211:SPITH_RS03105
uniprot id: G0GA50
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

869211:SPITH RS01625
gene id: 869211:SPITH_RS01625
uniprot id: G0GDX9
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.

869211:SPITH RS06890
gene id: 869211:SPITH_RS06890
uniprot id: G0GFS7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

869211:SPITH RS09785
gene id: 869211:SPITH_RS09785
uniprot id: G0GDP7
names: Similarity
messages: Belongs to the LarC family.

869211:SPITH RS04865
gene id: 869211:SPITH_RS04865
uniprot id: G0GCE5
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

869211:SPITH RS06395
gene id: 869211:SPITH_RS06395
uniprot id: G0GEW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS06690
gene id: 869211:SPITH_RS06690
uniprot id: G0GFG7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

869211:SPITH RS11125
gene id: 869211:SPITH_RS11125
uniprot id: E6JTG4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

869211:SPITH RS08410
gene id: 869211:SPITH_RS08410
uniprot id: G0GBA0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

869211:SPITH RS08620
gene id: 869211:SPITH_RS08620
uniprot id: G0GBE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

869211:SPITH RS05565
gene id: 869211:SPITH_RS05565
uniprot id: G0GDM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

869211:SPITH RS11365
gene id: 869211:SPITH_RS11365
uniprot id: G0GG10
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

869211:SPITH RS09220
gene id: 869211:SPITH_RS09220
uniprot id: G0GCJ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

869211:SPITH RS05245
gene id: 869211:SPITH_RS05245
uniprot id: G0GD11
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

869211:SPITH RS01825
gene id: 869211:SPITH_RS01825
uniprot id: G0GE16
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

869211:SPITH RS05555
gene id: 869211:SPITH_RS05555
uniprot id: G0GDL7
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS01425
gene id: 869211:SPITH_RS01425
uniprot id: G0GDE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

869211:SPITH RS00670
gene id: 869211:SPITH_RS00670
uniprot id: G0GC58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

869211:SPITH RS11300
gene id: 869211:SPITH_RS11300
uniprot id: G0GFZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

869211:SPITH RS03055
gene id: 869211:SPITH_RS03055
uniprot id: G0G9Y1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

869211:SPITH RS03990
gene id: 869211:SPITH_RS03990
uniprot id: G0GB33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

869211:SPITH RS02985
gene id: 869211:SPITH_RS02985
uniprot id: G0G9W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

869211:SPITH RS01800
gene id: 869211:SPITH_RS01800
uniprot id: G0GE11
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

869211:SPITH RS02335
gene id: 869211:SPITH_RS02335
uniprot id: G0GF46
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS04820
gene id: 869211:SPITH_RS04820
uniprot id: G0GCD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

869211:SPITH RS08800
gene id: 869211:SPITH_RS08800
uniprot id: G0GBX4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

869211:SPITH RS06330
gene id: 869211:SPITH_RS06330
uniprot id: G0GEV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

869211:SPITH RS02370
gene id: 869211:SPITH_RS02370
uniprot id: G0GF53
names: Similarity
messages: Belongs to the SAICAR synthetase family.

869211:SPITH RS00350
gene id: 869211:SPITH_RS00350
uniprot id: G0GBJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

869211:SPITH RS03060
gene id: 869211:SPITH_RS03060
uniprot id: G0G9Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

869211:SPITH RS06505
gene id: 869211:SPITH_RS06505
uniprot id: G0GFD0
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS00585
gene id: 869211:SPITH_RS00585
uniprot id: G0GC41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

869211:SPITH RS08010
gene id: 869211:SPITH_RS08010
uniprot id: G0GAT1
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

869211:SPITH RS04060
gene id: 869211:SPITH_RS04060
uniprot id: G0GB47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

869211:SPITH RS10665
gene id: 869211:SPITH_RS10665
uniprot id: G0GF07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

869211:SPITH RS10175
gene id: 869211:SPITH_RS10175
uniprot id: G0GEB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

869211:SPITH RS08580
gene id: 869211:SPITH_RS08580
uniprot id: G0GBD4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

869211:SPITH RS09585
gene id: 869211:SPITH_RS09585
uniprot id: G0GD60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

869211:SPITH RS06790
gene id: 869211:SPITH_RS06790
uniprot id: G0GFQ7
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS07135
gene id: 869211:SPITH_RS07135
uniprot id: G0GFX4
names: Function
names: Subcellular Location Annotation
messages: Component of the core of the flagella.
messages: Periplasmic flagellum

869211:SPITH RS05935
gene id: 869211:SPITH_RS05935
uniprot id: G0GE87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

869211:SPITH RS07450
gene id: 869211:SPITH_RS07450
uniprot id: G0GA35
names: Function
names: Similarity
messages: Belongs to the bacterial histone-like protein family.
messages: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.

869211:SPITH RS11435
gene id: 869211:SPITH_RS11435
uniprot id: G0GG22
names: Subcellular Location Annotation
messages: Cytoplasm

869211:SPITH RS00010
gene id: 869211:SPITH_RS00010
uniprot id: G0GAY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

869211:SPITH RS06920
gene id: 869211:SPITH_RS06920
uniprot id: G0GFT3
names: Similarity
messages: Belongs to the YggT family.

869211:SPITH RS09355
gene id: 869211:SPITH_RS09355
uniprot id: G0GCM5
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS03330
gene id: 869211:SPITH_RS03330
uniprot id: G0GA93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

869211:SPITH RS10455
gene id: 869211:SPITH_RS10455
uniprot id: G0GEH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

869211:SPITH RS03045
gene id: 869211:SPITH_RS03045
uniprot id: G0G9X9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

869211:SPITH RS07080
gene id: 869211:SPITH_RS07080
uniprot id: G0GFW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

869211:SPITH RS02875
gene id: 869211:SPITH_RS02875
uniprot id: G0G9U8
names: Similarity
messages: Belongs to the aspartokinase family.

869211:SPITH RS03640
gene id: 869211:SPITH_RS03640
uniprot id: G0GAM6
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

869211:SPITH RS08390
gene id: 869211:SPITH_RS08390
uniprot id: G0GB96
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

869211:SPITH RS01560
gene id: 869211:SPITH_RS01560
uniprot id: G0GDW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

869211:SPITH RS09425
gene id: 869211:SPITH_RS09425
uniprot id: G0GD30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

869211:SPITH RS02610
gene id: 869211:SPITH_RS02610
uniprot id: G0GF95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

869211:SPITH RS09070
gene id: 869211:SPITH_RS09070
uniprot id: G0GCG9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

869211:SPITH RS03825
gene id: 869211:SPITH_RS03825
uniprot id: G0GAR0
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

869211:SPITH RS09750
gene id: 869211:SPITH_RS09750
uniprot id: G0GDP0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

869211:SPITH RS01475
gene id: 869211:SPITH_RS01475
uniprot id: G0GDF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

869211:SPITH RS07045
gene id: 869211:SPITH_RS07045
uniprot id: G0GFV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

869211:SPITH RS09925
gene id: 869211:SPITH_RS09925
uniprot id: G0GDS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

869211:SPITH RS09690
gene id: 869211:SPITH_RS09690
uniprot id: G0GD82
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

869211:SPITH RS05125
gene id: 869211:SPITH_RS05125
uniprot id: G0GCY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

869211:SPITH RS04310
gene id: 869211:SPITH_RS04310
uniprot id: G0GBP3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS09240
gene id: 869211:SPITH_RS09240
uniprot id: G0GCK2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

869211:SPITH RS05495
gene id: 869211:SPITH_RS05495
uniprot id: G0GDK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

869211:SPITH RS02730
gene id: 869211:SPITH_RS02730
uniprot id: G0G9R9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

869211:SPITH RS04425
gene id: 869211:SPITH_RS04425
uniprot id: G0GBR6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS08970
gene id: 869211:SPITH_RS08970
uniprot id: G0GC05
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

869211:SPITH RS05335
gene id: 869211:SPITH_RS05335
uniprot id: G0GDH4
names: Similarity
messages: Belongs to the glutamate synthase family.

869211:SPITH RS11075
gene id: 869211:SPITH_RS11075
uniprot id: G0GFM9
names: Similarity
messages: Belongs to the UMP kinase family.

869211:SPITH RS06340
gene id: 869211:SPITH_RS06340
uniprot id: G0GEV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

869211:SPITH RS04430
gene id: 869211:SPITH_RS04430
uniprot id: G0GBR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

869211:SPITH RS09420
gene id: 869211:SPITH_RS09420
uniprot id: G0GD29
names: Similarity
messages: Belongs to the BMP lipoprotein family.

869211:SPITH RS07970
gene id: 869211:SPITH_RS07970
uniprot id: G0GAS3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

869211:SPITH RS00265
gene id: 869211:SPITH_RS00265
uniprot id: G0GBI2
names: Similarity
messages: Belongs to the threonine synthase family.

869211:SPITH RS10695
gene id: 869211:SPITH_RS10695
uniprot id: G0GF13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS04090
gene id: 869211:SPITH_RS04090
uniprot id: G0GB53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

869211:SPITH RS07565
gene id: 869211:SPITH_RS07565
uniprot id: G0GAC4
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS04190
gene id: 869211:SPITH_RS04190
uniprot id: G0GB71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

869211:SPITH RS04075
gene id: 869211:SPITH_RS04075
uniprot id: G0GB50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

869211:SPITH RS10125
gene id: 869211:SPITH_RS10125
uniprot id: G0GEA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

869211:SPITH RS10165
gene id: 869211:SPITH_RS10165
uniprot id: G0GEB6
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS07815
gene id: 869211:SPITH_RS07815
uniprot id: G0GAH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS09650
gene id: 869211:SPITH_RS09650
uniprot id: G0GD74
names: Similarity
messages: Belongs to the IMPACT family.

869211:SPITH RS02665
gene id: 869211:SPITH_RS02665
uniprot id: G0GFA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

869211:SPITH RS04420
gene id: 869211:SPITH_RS04420
uniprot id: G0GBR5
names: Similarity
messages: Belongs to the UPF0758 family.

869211:SPITH RS01490
gene id: 869211:SPITH_RS01490
uniprot id: G0GDF7
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS03005
gene id: 869211:SPITH_RS03005
uniprot id: G0G9X1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

869211:SPITH RS08305
gene id: 869211:SPITH_RS08305
uniprot id: G0GB79
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

869211:SPITH RS03000
gene id: 869211:SPITH_RS03000
uniprot id: G0G9X0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

869211:SPITH RS02580
gene id: 869211:SPITH_RS02580
uniprot id: G0GF89
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

869211:SPITH RS07800
gene id: 869211:SPITH_RS07800
uniprot id: E6JTG4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

869211:SPITH RS02750
gene id: 869211:SPITH_RS02750
uniprot id: G0G9S3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

869211:SPITH RS08230
gene id: 869211:SPITH_RS08230
uniprot id: G0GAX5
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS06945
gene id: 869211:SPITH_RS06945
uniprot id: G0GFT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

869211:SPITH RS11530
gene id: 869211:SPITH_RS11530
uniprot id: G0GG42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

869211:SPITH RS04050
gene id: 869211:SPITH_RS04050
uniprot id: G0GB45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

869211:SPITH RS06915
gene id: 869211:SPITH_RS06915
uniprot id: G0GFT2
names: Subcellular Location Annotation
messages: Cytoplasm

869211:SPITH RS04465
gene id: 869211:SPITH_RS04465
uniprot id: G0GBS4
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. Glucosylglycerate phosphorylase subfamily.
messages: Catalyzes the reversible phosphorolysis of glucosylglycerate into alpha-D-glucose 1-phosphate (Glc1P) and D-glycerate. May be a regulator of intracellular levels of glucosylglycerate, a compatible solute that primarily protects organisms facing salt stress and very specific nutritional constraints. Cannot catalyze the phosphorolysis of sucrose.

869211:SPITH RS02725
gene id: 869211:SPITH_RS02725
uniprot id: G0G9R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

869211:SPITH RS04705
gene id: 869211:SPITH_RS04705
uniprot id: G0GCB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

869211:SPITH RS09980
gene id: 869211:SPITH_RS09980
uniprot id: G0GDT6
names: Similarity
messages: Belongs to the BMP lipoprotein family.

869211:SPITH RS08570
gene id: 869211:SPITH_RS08570
uniprot id: G0GBD2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

869211:SPITH RS06385
gene id: 869211:SPITH_RS06385
uniprot id: G0GEW3
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS11955
gene id: 869211:SPITH_RS11955
uniprot id: G0GDL8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

869211:SPITH RS08070
gene id: 869211:SPITH_RS08070
uniprot id: G0GAU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

869211:SPITH RS04860
gene id: 869211:SPITH_RS04860
uniprot id: G0GCE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

869211:SPITH RS00565
gene id: 869211:SPITH_RS00565
uniprot id: G0GC37
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS05810
gene id: 869211:SPITH_RS05810
uniprot id: G0GE62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

869211:SPITH RS05825
gene id: 869211:SPITH_RS05825
uniprot id: G0GE65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

869211:SPITH RS04665
gene id: 869211:SPITH_RS04665
uniprot id: G0GCA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

869211:SPITH RS02710
gene id: 869211:SPITH_RS02710
uniprot id: G0G9R5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

869211:SPITH RS06425
gene id: 869211:SPITH_RS06425
uniprot id: G0GFB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

869211:SPITH RS01430
gene id: 869211:SPITH_RS01430
uniprot id: G0GDE4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

869211:SPITH RS08380
gene id: 869211:SPITH_RS08380
uniprot id: G0GB94
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

869211:SPITH RS01900
gene id: 869211:SPITH_RS01900
uniprot id: G0GE30
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

869211:SPITH RS03155
gene id: 869211:SPITH_RS03155
uniprot id: G0GA58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

869211:SPITH RS09350
gene id: 869211:SPITH_RS09350
uniprot id: G0GCM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

869211:SPITH RS03230
gene id: 869211:SPITH_RS03230
uniprot id: G0GA73
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

869211:SPITH RS01990
gene id: 869211:SPITH_RS01990
uniprot id: G0GEJ1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

869211:SPITH RS04720
gene id: 869211:SPITH_RS04720
uniprot id: G0GCB6
names: Similarity
messages: Belongs to the DprA/Smf family.

869211:SPITH RS06580
gene id: 869211:SPITH_RS06580
uniprot id: G0GFE5
names: Similarity
messages: Belongs to the GARS family.

869211:SPITH RS09605
gene id: 869211:SPITH_RS09605
uniprot id: G0GD64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

869211:SPITH RS06065
gene id: 869211:SPITH_RS06065
uniprot id: G0GEQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

869211:SPITH RS10055
gene id: 869211:SPITH_RS10055
uniprot id: G0GDV1
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS03765
gene id: 869211:SPITH_RS03765
uniprot id: G0GAP8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

869211:SPITH RS01960
gene id: 869211:SPITH_RS01960
uniprot id: G0GEI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

869211:SPITH RS03425
gene id: 869211:SPITH_RS03425
uniprot id: G0GAB1
names: Similarity
messages: Belongs to the RecJ family.

869211:SPITH RS07095
gene id: 869211:SPITH_RS07095
uniprot id: G0GFW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Periplasm
messages: Periplasmic flagellum
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.

869211:SPITH RS09320
gene id: 869211:SPITH_RS09320
uniprot id: G0GCL8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

869211:SPITH RS11545
gene id: 869211:SPITH_RS11545
uniprot id: G0GG45
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

869211:SPITH RS03065
gene id: 869211:SPITH_RS03065
uniprot id: G0G9Y3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

869211:SPITH RS08375
gene id: 869211:SPITH_RS08375
uniprot id: G0GB93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

869211:SPITH RS08540
gene id: 869211:SPITH_RS08540
uniprot id: G0GBC6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

869211:SPITH RS06865
gene id: 869211:SPITH_RS06865
uniprot id: G0GFS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS10585
gene id: 869211:SPITH_RS10585
uniprot id: G0GEZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

869211:SPITH RS11335
gene id: 869211:SPITH_RS11335
uniprot id: G0GG04
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

869211:SPITH RS04710
gene id: 869211:SPITH_RS04710
uniprot id: G0GCB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

869211:SPITH RS08685
gene id: 869211:SPITH_RS08685
uniprot id: G0GBV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

869211:SPITH RS04625
gene id: 869211:SPITH_RS04625
uniprot id: G0GC97
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

869211:SPITH RS04620
gene id: 869211:SPITH_RS04620
uniprot id: G0GC96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS00220
gene id: 869211:SPITH_RS00220
uniprot id: G0GBH3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

869211:SPITH RS02785
gene id: 869211:SPITH_RS02785
uniprot id: G0G9T0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

869211:SPITH RS04370
gene id: 869211:SPITH_RS04370
uniprot id: G0GBQ5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

869211:SPITH RS07025
gene id: 869211:SPITH_RS07025
uniprot id: G0GFV2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

869211:SPITH RS07010
gene id: 869211:SPITH_RS07010
uniprot id: G0GFU9
names: Subcellular Location Annotation
messages: Periplasmic flagellum

869211:SPITH RS06775
gene id: 869211:SPITH_RS06775
uniprot id: G0GFI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

869211:SPITH RS11895
gene id: 869211:SPITH_RS11895
uniprot id: G0GFB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

869211:SPITH RS06315
gene id: 869211:SPITH_RS06315
uniprot id: G0GEV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

869211:SPITH RS10180
gene id: 869211:SPITH_RS10180
uniprot id: G0GEB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

869211:SPITH RS00645
gene id: 869211:SPITH_RS00645
uniprot id: G0GC53
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

869211:SPITH RS02975
gene id: 869211:SPITH_RS02975
uniprot id: G0G9W5
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

869211:SPITH RS09575
gene id: 869211:SPITH_RS09575
uniprot id: G0GD58
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS05285
gene id: 869211:SPITH_RS05285
uniprot id: G0GD19
names: Subcellular Location Annotation
messages: Nucleus

869211:SPITH RS04065
gene id: 869211:SPITH_RS04065
uniprot id: G0GB48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS01105
gene id: 869211:SPITH_RS01105
uniprot id: G0GCT7
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

869211:SPITH RS05920
gene id: 869211:SPITH_RS05920
uniprot id: G0GE84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

869211:SPITH RS09190
gene id: 869211:SPITH_RS09190
uniprot id: G0GCJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS04255
gene id: 869211:SPITH_RS04255
uniprot id: G0GBN1
names: Similarity
messages: Belongs to the P(II) protein family.

869211:SPITH RS03650
gene id: 869211:SPITH_RS03650
uniprot id: G0GAM8
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

869211:SPITH RS09665
gene id: 869211:SPITH_RS09665
uniprot id: G0GD77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS06675
gene id: 869211:SPITH_RS06675
uniprot id: G0GFG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

869211:SPITH RS00500
gene id: 869211:SPITH_RS00500
uniprot id: G0GC24
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS05120
gene id: 869211:SPITH_RS05120
uniprot id: G0GCY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

869211:SPITH RS03675
gene id: 869211:SPITH_RS03675
uniprot id: G0GAN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS00355
gene id: 869211:SPITH_RS00355
uniprot id: G0GBK0
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

869211:SPITH RS10610
gene id: 869211:SPITH_RS10610
uniprot id: G0GEZ6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

869211:SPITH RS03295
gene id: 869211:SPITH_RS03295
uniprot id: G0GA86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

869211:SPITH RS08000
gene id: 869211:SPITH_RS08000
uniprot id: G0GAS9
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

869211:SPITH RS00995
gene id: 869211:SPITH_RS00995
uniprot id: G0GCR6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

869211:SPITH RS09000
gene id: 869211:SPITH_RS09000
uniprot id: G0GC11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

869211:SPITH RS09295
gene id: 869211:SPITH_RS09295
uniprot id: G0GCL3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

869211:SPITH RS08015
gene id: 869211:SPITH_RS08015
uniprot id: G0GAT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS09810
gene id: 869211:SPITH_RS09810
uniprot id: G0GDQ2
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS10680
gene id: 869211:SPITH_RS10680
uniprot id: G0GF10
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS08455
gene id: 869211:SPITH_RS08455
uniprot id: G0GBA9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

869211:SPITH RS05485
gene id: 869211:SPITH_RS05485
uniprot id: G0GDK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

869211:SPITH RS02240
gene id: 869211:SPITH_RS02240
uniprot id: G0GEN9
names: Similarity
messages: Belongs to the UPF0423 family.

869211:SPITH RS04005
gene id: 869211:SPITH_RS04005
uniprot id: G0GB36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

869211:SPITH RS04185
gene id: 869211:SPITH_RS04185
uniprot id: G0GB70
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

869211:SPITH RS08885
gene id: 869211:SPITH_RS08885
uniprot id: G0GBZ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

869211:SPITH RS11210
gene id: 869211:SPITH_RS11210
uniprot id: G0GFQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.

869211:SPITH RS01980
gene id: 869211:SPITH_RS01980
uniprot id: G0GEJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS01000
gene id: 869211:SPITH_RS01000
uniprot id: G0GCR7
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

869211:SPITH RS07995
gene id: 869211:SPITH_RS07995
uniprot id: G0GAS8
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS04660
gene id: 869211:SPITH_RS04660
uniprot id: G0GCA4
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

869211:SPITH RS00540
gene id: 869211:SPITH_RS00540
uniprot id: G0GC32
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

869211:SPITH RS09970
gene id: 869211:SPITH_RS09970
uniprot id: G0GDT4
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS11615
gene id: 869211:SPITH_RS11615
uniprot id: G0GG59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

869211:SPITH RS11420
gene id: 869211:SPITH_RS11420
uniprot id: G0GG19
names: Similarity
messages: Belongs to the sigma-54 factor family.

869211:SPITH RS01170
gene id: 869211:SPITH_RS01170
uniprot id: G0GCV0
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Secreted

869211:SPITH RS11505
gene id: 869211:SPITH_RS11505
uniprot id: G0GG37
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

869211:SPITH RS05500
gene id: 869211:SPITH_RS05500
uniprot id: G0GDK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

869211:SPITH RS03475
gene id: 869211:SPITH_RS03475
uniprot id: G0GAJ2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

869211:SPITH RS03555
gene id: 869211:SPITH_RS03555
uniprot id: G0GAK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

869211:SPITH RS10230
gene id: 869211:SPITH_RS10230
uniprot id: G0GEC9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

869211:SPITH RS01550
gene id: 869211:SPITH_RS01550
uniprot id: G0GDW3
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS01350
gene id: 869211:SPITH_RS01350
uniprot id: G0GDC8
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS11205
gene id: 869211:SPITH_RS11205
uniprot id: G0GFQ4
names: Similarity
messages: Belongs to the fabD family.

869211:SPITH RS04750
gene id: 869211:SPITH_RS04750
uniprot id: G0GCC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

869211:SPITH RS02920
gene id: 869211:SPITH_RS02920
uniprot id: G0G9V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

869211:SPITH RS06075
gene id: 869211:SPITH_RS06075
uniprot id: G0GEQ9
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

869211:SPITH RS02225
gene id: 869211:SPITH_RS02225
uniprot id: G0GEN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

869211:SPITH RS08615
gene id: 869211:SPITH_RS08615
uniprot id: G0GBE1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

869211:SPITH RS10235
gene id: 869211:SPITH_RS10235
uniprot id: G0GED0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

869211:SPITH RS08480
gene id: 869211:SPITH_RS08480
uniprot id: G0GBB4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS00195
gene id: 869211:SPITH_RS00195
uniprot id: G0GBG8
names: Similarity
messages: Belongs to the UPF0047 family.

869211:SPITH RS01145
gene id: 869211:SPITH_RS01145
uniprot id: G0GCU5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

869211:SPITH RS04810
gene id: 869211:SPITH_RS04810
uniprot id: G0GCD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

869211:SPITH RS05510
gene id: 869211:SPITH_RS05510
uniprot id: G0GDK8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

869211:SPITH RS00655
gene id: 869211:SPITH_RS00655
uniprot id: G0GC55
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

869211:SPITH RS05215
gene id: 869211:SPITH_RS05215
uniprot id: G0GD05
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

869211:SPITH RS02250
gene id: 869211:SPITH_RS02250
uniprot id: G0GEP1
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS10345
gene id: 869211:SPITH_RS10345
uniprot id: G0GEF2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

869211:SPITH RS08715
gene id: 869211:SPITH_RS08715
uniprot id: G0GBV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

869211:SPITH RS00285
gene id: 869211:SPITH_RS00285
uniprot id: G0GBI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

869211:SPITH RS04020
gene id: 869211:SPITH_RS04020
uniprot id: G0GB39
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

869211:SPITH RS04305
gene id: 869211:SPITH_RS04305
uniprot id: G0GBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

869211:SPITH RS01135
gene id: 869211:SPITH_RS01135
uniprot id: G0GCU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

869211:SPITH RS00025
gene id: 869211:SPITH_RS00025
uniprot id: G0GAZ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

869211:SPITH RS07720
gene id: 869211:SPITH_RS07720
uniprot id: G0GAF5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

869211:SPITH RS11305
gene id: 869211:SPITH_RS11305
uniprot id: G0GFZ8
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS09140
gene id: 869211:SPITH_RS09140
uniprot id: G0GCI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

869211:SPITH RS08625
gene id: 869211:SPITH_RS08625
uniprot id: G0GBE3
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

869211:SPITH RS09365
gene id: 869211:SPITH_RS09365
uniprot id: G0GCM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

869211:SPITH RS00430
gene id: 869211:SPITH_RS00430
uniprot id: G0GBL5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

869211:SPITH RS05505
gene id: 869211:SPITH_RS05505
uniprot id: G0GDK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

869211:SPITH RS08085
gene id: 869211:SPITH_RS08085
uniprot id: G0GAU6
names: Similarity
messages: Belongs to the peptidase A24 family.

869211:SPITH RS05725
gene id: 869211:SPITH_RS05725
uniprot id: G0GE45
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

869211:SPITH RS11540
gene id: 869211:SPITH_RS11540
uniprot id: G0GG44
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

869211:SPITH RS11480
gene id: 869211:SPITH_RS11480
uniprot id: G0GG32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS09965
gene id: 869211:SPITH_RS09965
uniprot id: G0GDT3
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS05575
gene id: 869211:SPITH_RS05575
uniprot id: G0GDM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

869211:SPITH RS03165
gene id: 869211:SPITH_RS03165
uniprot id: G0GA60
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

869211:SPITH RS05815
gene id: 869211:SPITH_RS05815
uniprot id: G0GE63
names: Similarity
messages: Belongs to the RibF family.

869211:SPITH RS02915
gene id: 869211:SPITH_RS02915
uniprot id: G0G9V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

869211:SPITH RS01160
gene id: 869211:SPITH_RS01160
uniprot id: G0GCU8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

869211:SPITH RS01525
gene id: 869211:SPITH_RS01525
uniprot id: G0GDG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

869211:SPITH RS03265
gene id: 869211:SPITH_RS03265
uniprot id: G0GA80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

869211:SPITH RS11080
gene id: 869211:SPITH_RS11080
uniprot id: G0GFN0
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

869211:SPITH RS04115
gene id: 869211:SPITH_RS04115
uniprot id: G0GB56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

869211:SPITH RS02085
gene id: 869211:SPITH_RS02085
uniprot id: G0GEK9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

869211:SPITH RS02635
gene id: 869211:SPITH_RS02635
uniprot id: G0GFA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

869211:SPITH RS10845
gene id: 869211:SPITH_RS10845
uniprot id: G0GF38
names: Similarity
messages: Belongs to the Nudix hydrolase family.

869211:SPITH RS00140
gene id: 869211:SPITH_RS00140
uniprot id: G0GBF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS10655
gene id: 869211:SPITH_RS10655
uniprot id: G0GF05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS01240
gene id: 869211:SPITH_RS01240
uniprot id: G0GDA6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

869211:SPITH RS01820
gene id: 869211:SPITH_RS01820
uniprot id: G0GE15
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

869211:SPITH RS03755
gene id: 869211:SPITH_RS03755
uniprot id: G0GAP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

869211:SPITH RS05050
gene id: 869211:SPITH_RS05050
uniprot id: G0GCX2
names: Subcellular Location Annotation
messages: Periplasmic flagellum

869211:SPITH RS00375
gene id: 869211:SPITH_RS00375
uniprot id: G0GBK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS06645
gene id: 869211:SPITH_RS06645
uniprot id: G0GFF8
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS01485
gene id: 869211:SPITH_RS01485
uniprot id: G0GDF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

869211:SPITH RS04445
gene id: 869211:SPITH_RS04445
uniprot id: G0GBS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

869211:SPITH RS06845
gene id: 869211:SPITH_RS06845
uniprot id: G0GFR8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

869211:SPITH RS08770
gene id: 869211:SPITH_RS08770
uniprot id: G0GBW8
names: Similarity
messages: Belongs to the UPF0166 family.

869211:SPITH RS09595
gene id: 869211:SPITH_RS09595
uniprot id: G0GD62
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

869211:SPITH RS02800
gene id: 869211:SPITH_RS02800
uniprot id: G0G9T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

869211:SPITH RS01470
gene id: 869211:SPITH_RS01470
uniprot id: G0GDF3
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

869211:SPITH RS10020
gene id: 869211:SPITH_RS10020
uniprot id: G0GDU4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS05095
gene id: 869211:SPITH_RS05095
uniprot id: G0GCY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

869211:SPITH RS04495
gene id: 869211:SPITH_RS04495
uniprot id: G0GBS9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS02630
gene id: 869211:SPITH_RS02630
uniprot id: G0GF99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

869211:SPITH RS05345
gene id: 869211:SPITH_RS05345
uniprot id: G0GDH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

869211:SPITH RS05420
gene id: 869211:SPITH_RS05420
uniprot id: G0GDJ1
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

869211:SPITH RS06795
gene id: 869211:SPITH_RS06795
uniprot id: G0GFQ8
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS04760
gene id: 869211:SPITH_RS04760
uniprot id: G0GCC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

869211:SPITH RS11020
gene id: 869211:SPITH_RS11020
uniprot id: G0GFL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

869211:SPITH RS05445
gene id: 869211:SPITH_RS05445
uniprot id: G0GDJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

869211:SPITH RS06960
gene id: 869211:SPITH_RS06960
uniprot id: G0GFU1
names: Subcellular Location Annotation
messages: Cytoplasm

869211:SPITH RS06110
gene id: 869211:SPITH_RS06110
uniprot id: G0GER6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

869211:SPITH RS11900
gene id: 869211:SPITH_RS11900
uniprot id: G0G9V2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bTHX family.

869211:SPITH RS05970
gene id: 869211:SPITH_RS05970
uniprot id: G0GE95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

869211:SPITH RS11270
gene id: 869211:SPITH_RS11270
uniprot id: G0GFZ1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

869211:SPITH RS09230
gene id: 869211:SPITH_RS09230
uniprot id: G0GCK0
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

869211:SPITH RS01945
gene id: 869211:SPITH_RS01945
uniprot id: G0GEI3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

869211:SPITH RS02795
gene id: 869211:SPITH_RS02795
uniprot id: G0G9T2
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

869211:SPITH RS03935
gene id: 869211:SPITH_RS03935
uniprot id: G0GB22
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

869211:SPITH RS10005
gene id: 869211:SPITH_RS10005
uniprot id: G0GDU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS08090
gene id: 869211:SPITH_RS08090
uniprot id: G0GAU7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

869211:SPITH RS09535
gene id: 869211:SPITH_RS09535
uniprot id: G0GD50
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

869211:SPITH RS00250
gene id: 869211:SPITH_RS00250
uniprot id: G0GBH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS06405
gene id: 869211:SPITH_RS06405
uniprot id: G0GEW7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

869211:SPITH RS08605
gene id: 869211:SPITH_RS08605
uniprot id: G0GBD9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

869211:SPITH RS10540
gene id: 869211:SPITH_RS10540
uniprot id: G0GEY3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

869211:SPITH RS09845
gene id: 869211:SPITH_RS09845
uniprot id: G0GDQ9
names: Similarity
messages: Belongs to the Dps family.

869211:SPITH RS10280
gene id: 869211:SPITH_RS10280
uniprot id: G0GED9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869211:SPITH RS09105
gene id: 869211:SPITH_RS09105
uniprot id: G0GCH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

869211:SPITH RS07175
gene id: 869211:SPITH_RS07175
uniprot id: G0G9Y7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

869211:SPITH RS09200
gene id: 869211:SPITH_RS09200
uniprot id: G0GCJ4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

869211:SPITH RS11465
gene id: 869211:SPITH_RS11465
uniprot id: G0GG28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

869211:SPITH RS00260
gene id: 869211:SPITH_RS00260
uniprot id: G0GBI1
names: Similarity
messages: Belongs to the aspartokinase family.

869211:SPITH RS01890
gene id: 869211:SPITH_RS01890
uniprot id: G0GE28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

869211:SPITH RS05145
gene id: 869211:SPITH_RS05145
uniprot id: G0GCZ1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

869211:SPITH RS07170
gene id: 869211:SPITH_RS07170
uniprot id: G0G9Y6
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

869211:SPITH RS09100
gene id: 869211:SPITH_RS09100
uniprot id: G0GCH5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

869211:SPITH RS03440
gene id: 869211:SPITH_RS03440
uniprot id: G0GAB4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

869211:SPITH RS11230
gene id: 869211:SPITH_RS11230
uniprot id: G0GFY2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

869211:SPITH RS11045
gene id: 869211:SPITH_RS11045
uniprot id: G0GFM3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

869211:SPITH RS08765
gene id: 869211:SPITH_RS08765
uniprot id: G0GBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

869211:SPITH RS04755
gene id: 869211:SPITH_RS04755
uniprot id: G0GCC3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

869211:SPITH RS05005
gene id: 869211:SPITH_RS05005
uniprot id: G0GCW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

869211:SPITH RS10760
gene id: 869211:SPITH_RS10760
uniprot id: G0GF23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

869211:SPITH RS01780
gene id: 869211:SPITH_RS01780
uniprot id: G0GE07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS09300
gene id: 869211:SPITH_RS09300
uniprot id: G0GCL4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

869211:SPITH RS04055
gene id: 869211:SPITH_RS04055
uniprot id: G0GB46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

869211:SPITH RS10480
gene id: 869211:SPITH_RS10480
uniprot id: G0GEX2
names: Similarity
messages: Belongs to the acylphosphatase family.

869211:SPITH RS02645
gene id: 869211:SPITH_RS02645
uniprot id: G0GFA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

869211:SPITH RS06355
gene id: 869211:SPITH_RS06355
uniprot id: G0GEV8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

869211:SPITH RS02735
gene id: 869211:SPITH_RS02735
uniprot id: G0G9S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

869211:SPITH RS06410
gene id: 869211:SPITH_RS06410
uniprot id: G0GEW8
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

869211:SPITH RS05360
gene id: 869211:SPITH_RS05360
uniprot id: G0GDH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

869211:SPITH RS01235
gene id: 869211:SPITH_RS01235
uniprot id: G0GDA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869211:SPITH RS04340
gene id: 869211:SPITH_RS04340
uniprot id: G0GBP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

869211:SPITH RS06345
gene id: 869211:SPITH_RS06345
uniprot id: G0GEV6
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

869211:SPITH RS02615
gene id: 869211:SPITH_RS02615
uniprot id: G0GF96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

869211:SPITH RS01610
gene id: 869211:SPITH_RS01610
uniprot id: G0GDX5
names: Similarity
messages: Belongs to the MEMO1 family.

869211:SPITH RS00850
gene id: 869211:SPITH_RS00850
uniprot id: G0GCN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

869211:SPITH RS10015
gene id: 869211:SPITH_RS10015
uniprot id: G0GDU3
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS09110
gene id: 869211:SPITH_RS09110
uniprot id: G0GCH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

869211:SPITH RS07705
gene id: 869211:SPITH_RS07705
uniprot id: G0GAF2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

869211:SPITH RS03685
gene id: 869211:SPITH_RS03685
uniprot id: G0GAN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

869211:SPITH RS02650
gene id: 869211:SPITH_RS02650
uniprot id: G0GFA3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

869211:SPITH RS10085
gene id: 869211:SPITH_RS10085
uniprot id: G0GDV7
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS09700
gene id: 869211:SPITH_RS09700
uniprot id: G0GD84
names: Function
names: Similarity
messages: Belongs to the bacterial histone-like protein family.
messages: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.

869211:SPITH RS04265
gene id: 869211:SPITH_RS04265
uniprot id: G0GBN3
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

869211:SPITH RS02770
gene id: 869211:SPITH_RS02770
uniprot id: G0G9S7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

869211:SPITH RS11660
gene id: 869211:SPITH_RS11660
uniprot id: G0GG63
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS09570
gene id: 869211:SPITH_RS09570
uniprot id: G0GD57
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

869211:SPITH RS05925
gene id: 869211:SPITH_RS05925
uniprot id: G0GE85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

869211:SPITH RS09865
gene id: 869211:SPITH_RS09865
uniprot id: G0GDR3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

869211:SPITH RS05490
gene id: 869211:SPITH_RS05490
uniprot id: G0GDK4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

869211:SPITH RS05110
gene id: 869211:SPITH_RS05110
uniprot id: G0GCY4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

869211:SPITH RS02380
gene id: 869211:SPITH_RS02380
uniprot id: G0GF55
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

869211:SPITH RS09065
gene id: 869211:SPITH_RS09065
uniprot id: G0GCG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

869211:SPITH RS04295
gene id: 869211:SPITH_RS04295
uniprot id: G0GBN9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

869211:SPITH RS01315
gene id: 869211:SPITH_RS01315
uniprot id: G0GDC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

869211:SPITH RS03160
gene id: 869211:SPITH_RS03160
uniprot id: G0GA59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

869211:SPITH RS08525
gene id: 869211:SPITH_RS08525
uniprot id: G0GBC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

869211:SPITH RS02850
gene id: 869211:SPITH_RS02850
uniprot id: G0G9U3
names: Subcellular Location Annotation
messages: Membrane

869211:SPITH RS00505
gene id: 869211:SPITH_RS00505
uniprot id: G0GC25
names: Similarity
messages: Belongs to the pyruvate kinase family.

869211:SPITH RS09735
gene id: 869211:SPITH_RS09735
uniprot id: G0GD92
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

869211:SPITH RS02755
gene id: 869211:SPITH_RS02755
uniprot id: G0G9S4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.