861:C4N20 RS07505
gene id: 861:C4N20_RS07505
uniprot id: A0A2P1S3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

861:C4N20 RS15100
gene id: 861:C4N20_RS15100
uniprot id: A0A2P1S7H9
names: Similarity
messages: Belongs to the CobH/CbiC family.

861:C4N20 RS13240
gene id: 861:C4N20_RS13240
uniprot id: A0A2P1S6F2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS04205
gene id: 861:C4N20_RS04205
uniprot id: A0A2P1S220
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

861:C4N20 RS15080
gene id: 861:C4N20_RS15080
uniprot id: A0A2P1S7G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the precorrin methyltransferase family.
messages: Homodimer.
messages: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.

861:C4N20 RS11105
gene id: 861:C4N20_RS11105
uniprot id: A0A2P1S5S7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

861:C4N20 RS11490
gene id: 861:C4N20_RS11490
uniprot id: A0A2P1S5U0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

861:C4N20 RS11545
gene id: 861:C4N20_RS11545
uniprot id: A0A2P1S5K1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS05135
gene id: 861:C4N20_RS05135
uniprot id: A0A2P1S2H5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

861:C4N20 RS10585
gene id: 861:C4N20_RS10585
uniprot id: A0A2P1S5I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

861:C4N20 RS03745
gene id: 861:C4N20_RS03745
uniprot id: A0A2P1S1T9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

861:C4N20 RS14265
gene id: 861:C4N20_RS14265
uniprot id: A0A2P1S7M5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

861:C4N20 RS13810
gene id: 861:C4N20_RS13810
uniprot id: A0A2P1S6R6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

861:C4N20 RS00800
gene id: 861:C4N20_RS00800
uniprot id: A0A2P1RZR9
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS13290
gene id: 861:C4N20_RS13290
uniprot id: A0A2P1S6J5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

861:C4N20 RS06470
gene id: 861:C4N20_RS06470
uniprot id: A0A2P1S2U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

861:C4N20 RS14825
gene id: 861:C4N20_RS14825
uniprot id: A0A2P1S7A6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

861:C4N20 RS08050
gene id: 861:C4N20_RS08050
uniprot id: A0A2P1S3Q8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

861:C4N20 RS04060
gene id: 861:C4N20_RS04060
uniprot id: A0A2P1S1J9
names: Similarity
messages: Belongs to the ArsC family.

861:C4N20 RS07600
gene id: 861:C4N20_RS07600
uniprot id: A0A2P1S3U5
names: Similarity
messages: Belongs to the arginase family.

861:C4N20 RS14800
gene id: 861:C4N20_RS14800
uniprot id: A0A2P1S7B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

861:C4N20 RS00600
gene id: 861:C4N20_RS00600
uniprot id: A0A2P1RZN3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS13850
gene id: 861:C4N20_RS13850
uniprot id: A0A2P1S6S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

861:C4N20 RS08755
gene id: 861:C4N20_RS08755
uniprot id: A0A2P1S4C9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

861:C4N20 RS08815
gene id: 861:C4N20_RS08815
uniprot id: A0A2P1S416
names: Subcellular Location Annotation
messages: Cytoplasm

861:C4N20 RS10720
gene id: 861:C4N20_RS10720
uniprot id: A0A2P1S565
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

861:C4N20 RS09675
gene id: 861:C4N20_RS09675
uniprot id: A0A2P1S4J7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

861:C4N20 RS09085
gene id: 861:C4N20_RS09085
uniprot id: A0A2P1S475
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

861:C4N20 RS04405
gene id: 861:C4N20_RS04405
uniprot id: A0A2P1S1R6
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS07575
gene id: 861:C4N20_RS07575
uniprot id: A0A2P1S3H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

861:C4N20 RS10265
gene id: 861:C4N20_RS10265
uniprot id: A0A2P1S4V5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

861:C4N20 RS02735
gene id: 861:C4N20_RS02735
uniprot id: A0A2P1S0Y5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

861:C4N20 RS04065
gene id: 861:C4N20_RS04065
uniprot id: A0A2P1S1J7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

861:C4N20 RS16330
gene id: 861:C4N20_RS16330
uniprot id: A0A2P1S8C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

861:C4N20 RS05715
gene id: 861:C4N20_RS05715
uniprot id: A0A2P1S2S0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

861:C4N20 RS03505
gene id: 861:C4N20_RS03505
uniprot id: A0A2P1S180
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

861:C4N20 RS03255
gene id: 861:C4N20_RS03255
uniprot id: A0A2P1S175
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

861:C4N20 RS05320
gene id: 861:C4N20_RS05320
uniprot id: A0A2P1S268
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

861:C4N20 RS07490
gene id: 861:C4N20_RS07490
uniprot id: A0A2P1S3C1
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

861:C4N20 RS13270
gene id: 861:C4N20_RS13270
uniprot id: A0A2P1S6H8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

861:C4N20 RS03385
gene id: 861:C4N20_RS03385
uniprot id: A0A2P1S195
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

861:C4N20 RS07325
gene id: 861:C4N20_RS07325
uniprot id: A0A2P1S3A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

861:C4N20 RS02695
gene id: 861:C4N20_RS02695
uniprot id: A0A2P1S0S9
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS09530
gene id: 861:C4N20_RS09530
uniprot id: A0A2P1S4F1
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

861:C4N20 RS13450
gene id: 861:C4N20_RS13450
uniprot id: A0A2P1S6K4
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS08270
gene id: 861:C4N20_RS08270
uniprot id: A0A2P1S439
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

861:C4N20 RS15135
gene id: 861:C4N20_RS15135
uniprot id: A0A2P1S7F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS00620
gene id: 861:C4N20_RS00620
uniprot id: A0A2P1RZS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

861:C4N20 RS11935
gene id: 861:C4N20_RS11935
uniprot id: A0A2P1S5R2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

861:C4N20 RS12210
gene id: 861:C4N20_RS12210
uniprot id: A0A2P1S5W7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

861:C4N20 RS00895
gene id: 861:C4N20_RS00895
uniprot id: A0A2P1RZT8
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS02930
gene id: 861:C4N20_RS02930
uniprot id: A0A2P1S1G1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

861:C4N20 RS16325
gene id: 861:C4N20_RS16325
uniprot id: A0A2P1S840
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

861:C4N20 RS00970
gene id: 861:C4N20_RS00970
uniprot id: A0A2P1S0A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

861:C4N20 RS14440
gene id: 861:C4N20_RS14440
uniprot id: A0A2P1S753
names: Similarity
messages: Belongs to the peptidase M24B family.

861:C4N20 RS05060
gene id: 861:C4N20_RS05060
uniprot id: A0A2P1S2V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

861:C4N20 RS08930
gene id: 861:C4N20_RS08930
uniprot id: A0A2P1S448
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

861:C4N20 RS06995
gene id: 861:C4N20_RS06995
uniprot id: A0A2P1S3J5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

861:C4N20 RS11330
gene id: 861:C4N20_RS11330
uniprot id: A0A2P1S5F7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

861:C4N20 RS14540
gene id: 861:C4N20_RS14540
uniprot id: A0A2P1S774
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

861:C4N20 RS13030
gene id: 861:C4N20_RS13030
uniprot id: A0A2P1S6E9
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

861:C4N20 RS04285
gene id: 861:C4N20_RS04285
uniprot id: A0A2P1S283
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

861:C4N20 RS10050
gene id: 861:C4N20_RS10050
uniprot id: A0A2P1S4R2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

861:C4N20 RS00875
gene id: 861:C4N20_RS00875
uniprot id: A0A2P1RZT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

861:C4N20 RS06265
gene id: 861:C4N20_RS06265
uniprot id: A0A2P1S2M6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

861:C4N20 RS07410
gene id: 861:C4N20_RS07410
uniprot id: A0A2P1S3B5
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS02185
gene id: 861:C4N20_RS02185
uniprot id: A0A2P1S0J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

861:C4N20 RS06665
gene id: 861:C4N20_RS06665
uniprot id: A0A2P1S3E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

861:C4N20 RS13965
gene id: 861:C4N20_RS13965
uniprot id: A0A2P1S8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS14595
gene id: 861:C4N20_RS14595
uniprot id: A0A2P1S760
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

861:C4N20 RS03675
gene id: 861:C4N20_RS03675
uniprot id: A0A2P1S1F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

861:C4N20 RS02290
gene id: 861:C4N20_RS02290
uniprot id: A0A2P1S102
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

861:C4N20 RS05370
gene id: 861:C4N20_RS05370
uniprot id: A0A2P1S266
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

861:C4N20 RS07855
gene id: 861:C4N20_RS07855
uniprot id: A0A2P1S3J3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

861:C4N20 RS01395
gene id: 861:C4N20_RS01395
uniprot id: A0A2P1S0J2
names: Similarity
messages: Belongs to the peptidase M29 family.

861:C4N20 RS09690
gene id: 861:C4N20_RS09690
uniprot id: A0A2P1S4Z9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS08590
gene id: 861:C4N20_RS08590
uniprot id: A0A2P1S3Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

861:C4N20 RS05345
gene id: 861:C4N20_RS05345
uniprot id: A0A2P1S8A9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

861:C4N20 RS02980
gene id: 861:C4N20_RS02980
uniprot id: A0A2P1S0Z1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS04030
gene id: 861:C4N20_RS04030
uniprot id: A0A2P1S1M2
names: Similarity
messages: Belongs to the UPF0371 family.

861:C4N20 RS13405
gene id: 861:C4N20_RS13405
uniprot id: A0A2P1S743
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

861:C4N20 RS01050
gene id: 861:C4N20_RS01050
uniprot id: A0A2P1S015
names: Similarity
messages: Belongs to the DNase I family.

861:C4N20 RS08395
gene id: 861:C4N20_RS08395
uniprot id: A0A2P1S3U2
names: Similarity
messages: Belongs to the peptidase M20A family.

861:C4N20 RS13130
gene id: 861:C4N20_RS13130
uniprot id: A0A2P1S6M1
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS06805
gene id: 861:C4N20_RS06805
uniprot id: A0A2P1S2Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

861:C4N20 RS16360
gene id: 861:C4N20_RS16360
uniprot id: A0A2P1S872
names: Similarity
messages: Belongs to the UPF0735 family.

861:C4N20 RS08150
gene id: 861:C4N20_RS08150
uniprot id: A0A2P1S3S4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

861:C4N20 RS08780
gene id: 861:C4N20_RS08780
uniprot id: A0A2P1S409
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

861:C4N20 RS09265
gene id: 861:C4N20_RS09265
uniprot id: A0A2P1S4C4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

861:C4N20 RS06460
gene id: 861:C4N20_RS06460
uniprot id: A0A2P1S2S2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

861:C4N20 RS06115
gene id: 861:C4N20_RS06115
uniprot id: A0A2P1S2J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

861:C4N20 RS02825
gene id: 861:C4N20_RS02825
uniprot id: A0A2P1S0V9
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS13955
gene id: 861:C4N20_RS13955
uniprot id: A0A2P1S6W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS12000
gene id: 861:C4N20_RS12000
uniprot id: A0A2P1S6A3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

861:C4N20 RS13600
gene id: 861:C4N20_RS13600
uniprot id: A0A2P1S6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

861:C4N20 RS13090
gene id: 861:C4N20_RS13090
uniprot id: A0A2P1S6D0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

861:C4N20 RS02150
gene id: 861:C4N20_RS02150
uniprot id: A0A2P1S0G7
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

861:C4N20 RS12155
gene id: 861:C4N20_RS12155
uniprot id: A0A2P1S8J1
names: Similarity
messages: Belongs to the MlaA family.

861:C4N20 RS06385
gene id: 861:C4N20_RS06385
uniprot id: A0A2P1S2X4
names: Similarity
messages: Belongs to the peptidase M18 family.

861:C4N20 RS11805
gene id: 861:C4N20_RS11805
uniprot id: A0A2P1S5N7
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

861:C4N20 RS06550
gene id: 861:C4N20_RS06550
uniprot id: A0A2P1S306
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

861:C4N20 RS09330
gene id: 861:C4N20_RS09330
uniprot id: A0A2P1S4A7
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS06885
gene id: 861:C4N20_RS06885
uniprot id: A0A2P1S321
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

861:C4N20 RS09745
gene id: 861:C4N20_RS09745
uniprot id: A0A2P1S4J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

861:C4N20 RS06230
gene id: 861:C4N20_RS06230
uniprot id: A0A2P1S2N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

861:C4N20 RS04695
gene id: 861:C4N20_RS04695
uniprot id: A0A2P1S1X6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861:C4N20 RS06725
gene id: 861:C4N20_RS06725
uniprot id: A0A2P1S2Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

861:C4N20 RS02835
gene id: 861:C4N20_RS02835
uniprot id: A0A2P1S100
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS04465
gene id: 861:C4N20_RS04465
uniprot id: A0A2P1S1W2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

861:C4N20 RS10450
gene id: 861:C4N20_RS10450
uniprot id: A0A2P1S4Z6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861:C4N20 RS10885
gene id: 861:C4N20_RS10885
uniprot id: A0A2P1S559
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

861:C4N20 RS05100
gene id: 861:C4N20_RS05100
uniprot id: A0A2P1S234
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS11815
gene id: 861:C4N20_RS11815
uniprot id: A0A2P1S5P2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

861:C4N20 RS12005
gene id: 861:C4N20_RS12005
uniprot id: A0A2P1S5S5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS14245
gene id: 861:C4N20_RS14245
uniprot id: A0A2P1S796
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

861:C4N20 RS08800
gene id: 861:C4N20_RS08800
uniprot id: A0A2P1S447
names: Cofactor
messages: Binds 1 zinc ion per subunit.

861:C4N20 RS13080
gene id: 861:C4N20_RS13080
uniprot id: A0A2P1S6K6
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS01815
gene id: 861:C4N20_RS01815
uniprot id: A0A2P1S0B9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS14370
gene id: 861:C4N20_RS14370
uniprot id: A0A2P1S7P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

861:C4N20 RS02645
gene id: 861:C4N20_RS02645
uniprot id: A0A2P1S0S0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

861:C4N20 RS03555
gene id: 861:C4N20_RS03555
uniprot id: A0A2P1S190
names: Similarity
messages: Belongs to the UxaA family.

861:C4N20 RS04300
gene id: 861:C4N20_RS04300
uniprot id: A0A2P1S1P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

861:C4N20 RS02860
gene id: 861:C4N20_RS02860
uniprot id: A0A2P1S1A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

861:C4N20 RS06515
gene id: 861:C4N20_RS06515
uniprot id: A0A2P1S2S6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

861:C4N20 RS06375
gene id: 861:C4N20_RS06375
uniprot id: A0A2P1S2T6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS02865
gene id: 861:C4N20_RS02865
uniprot id: A0A2P1S105
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

861:C4N20 RS06520
gene id: 861:C4N20_RS06520
uniprot id: A0A2P1S2V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

861:C4N20 RS10150
gene id: 861:C4N20_RS10150
uniprot id: A0A2P1S4T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

861:C4N20 RS13365
gene id: 861:C4N20_RS13365
uniprot id: A0A2P1S6J1
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

861:C4N20 RS00760
gene id: 861:C4N20_RS00760
uniprot id: A0A2P1RZR7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

861:C4N20 RS01170
gene id: 861:C4N20_RS01170
uniprot id: A0A2P1RZZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

861:C4N20 RS00750
gene id: 861:C4N20_RS00750
uniprot id: A0A2P1RZQ8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

861:C4N20 RS10900
gene id: 861:C4N20_RS10900
uniprot id: A0A2P1S560
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

861:C4N20 RS08570
gene id: 861:C4N20_RS08570
uniprot id: A0A2P1S3Y4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

861:C4N20 RS00995
gene id: 861:C4N20_RS00995
uniprot id: A0A2P1S002
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS12935
gene id: 861:C4N20_RS12935
uniprot id: A0A2P1S6A5
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS16105
gene id: 861:C4N20_RS16105
uniprot id: A0A2P1S804
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

861:C4N20 RS07140
gene id: 861:C4N20_RS07140
uniprot id: A0A2P1S342
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

861:C4N20 RS10110
gene id: 861:C4N20_RS10110
uniprot id: A0A2P1S4S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

861:C4N20 RS02960
gene id: 861:C4N20_RS02960
uniprot id: A0A2P1S0Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS11770
gene id: 861:C4N20_RS11770
uniprot id: A0A2P1S5L4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

861:C4N20 RS09020
gene id: 861:C4N20_RS09020
uniprot id: A0A2P1S455
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

861:C4N20 RS03580
gene id: 861:C4N20_RS03580
uniprot id: A0A2P1S1A3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

861:C4N20 RS08680
gene id: 861:C4N20_RS08680
uniprot id: A0A2P1S3Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

861:C4N20 RS09070
gene id: 861:C4N20_RS09070
uniprot id: A0A2P1S463
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

861:C4N20 RS13390
gene id: 861:C4N20_RS13390
uniprot id: A0A2P1S6K8
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

861:C4N20 RS00835
gene id: 861:C4N20_RS00835
uniprot id: A0A2P1S0C6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS15125
gene id: 861:C4N20_RS15125
uniprot id: A0A2P1S7R3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

861:C4N20 RS00020
gene id: 861:C4N20_RS00020
uniprot id: A0A2P1RZB6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

861:C4N20 RS06440
gene id: 861:C4N20_RS06440
uniprot id: A0A2P1S2V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

861:C4N20 RS07330
gene id: 861:C4N20_RS07330
uniprot id: A0A2P1S392
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

861:C4N20 RS09115
gene id: 861:C4N20_RS09115
uniprot id: A0A2P1S477
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS01980
gene id: 861:C4N20_RS01980
uniprot id: A0A2P1S0F4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

861:C4N20 RS06090
gene id: 861:C4N20_RS06090
uniprot id: A0A2P1S2L6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861:C4N20 RS07045
gene id: 861:C4N20_RS07045
uniprot id: A0A2P1S3K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

861:C4N20 RS11220
gene id: 861:C4N20_RS11220
uniprot id: A0A2P1S5B5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS05475
gene id: 861:C4N20_RS05475
uniprot id: A0A2P1S2A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

861:C4N20 RS09940
gene id: 861:C4N20_RS09940
uniprot id: A0A2P1S4P5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

861:C4N20 RS11060
gene id: 861:C4N20_RS11060
uniprot id: A0A2P1S590
names: Similarity
messages: Belongs to the AlaDH/PNT family.

861:C4N20 RS04195
gene id: 861:C4N20_RS04195
uniprot id: A0A2P1S1M7
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS16125
gene id: 861:C4N20_RS16125
uniprot id: A0A2P1S812
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

861:C4N20 RS07700
gene id: 861:C4N20_RS07700
uniprot id: A0A2P1S3W2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

861:C4N20 RS11610
gene id: 861:C4N20_RS11610
uniprot id: A0A2P1S5L0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

861:C4N20 RS10785
gene id: 861:C4N20_RS10785
uniprot id: A0A2P1S543
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

861:C4N20 RS12230
gene id: 861:C4N20_RS12230
uniprot id: A0A2P1S5W8
names: Similarity
messages: Belongs to the DSD1 family.

861:C4N20 RS02810
gene id: 861:C4N20_RS02810
uniprot id: A0A2P1S198
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

861:C4N20 RS11890
gene id: 861:C4N20_RS11890
uniprot id: A0A2P1S5P0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS16035
gene id: 861:C4N20_RS16035
uniprot id: A0A2P1S7Y5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

861:C4N20 RS01095
gene id: 861:C4N20_RS01095
uniprot id: A0A2P1RZY9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

861:C4N20 RS08965
gene id: 861:C4N20_RS08965
uniprot id: A0A2P1S449
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

861:C4N20 RS11500
gene id: 861:C4N20_RS11500
uniprot id: A0A2P1S5I1
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

861:C4N20 RS14040
gene id: 861:C4N20_RS14040
uniprot id: A0A2P1S6V9
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS00615
gene id: 861:C4N20_RS00615
uniprot id: A0A2P1S037
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS07620
gene id: 861:C4N20_RS07620
uniprot id: A0A2P1S3E0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS11845
gene id: 861:C4N20_RS11845
uniprot id: A0A2P1S674
names: Similarity
messages: Belongs to the arginase family.

861:C4N20 RS08855
gene id: 861:C4N20_RS08855
uniprot id: A0A2P1S4E9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

861:C4N20 RS08760
gene id: 861:C4N20_RS08760
uniprot id: A0A2P1S413
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

861:C4N20 RS13900
gene id: 861:C4N20_RS13900
uniprot id: A0A2P1S6T1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

861:C4N20 RS08420
gene id: 861:C4N20_RS08420
uniprot id: A0A2P1S466
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS13435
gene id: 861:C4N20_RS13435
uniprot id: A0A2P1S6U3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

861:C4N20 RS08405
gene id: 861:C4N20_RS08405
uniprot id: A0A2P1S3U6
names: Subcellular Location Annotation
messages: Cytoplasm

861:C4N20 RS13380
gene id: 861:C4N20_RS13380
uniprot id: A0A2P1S6I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

861:C4N20 RS03605
gene id: 861:C4N20_RS03605
uniprot id: A0A2P1S199
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

861:C4N20 RS00805
gene id: 861:C4N20_RS00805
uniprot id: A0A2P1RZS1
names: Similarity
messages: Belongs to the peptidase M20A family.

861:C4N20 RS05700
gene id: 861:C4N20_RS05700
uniprot id: A0A2P1S2F8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

861:C4N20 RS01260
gene id: 861:C4N20_RS01260
uniprot id: A0A2P1S053
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS07030
gene id: 861:C4N20_RS07030
uniprot id: A0A2P1S324
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

861:C4N20 RS11145
gene id: 861:C4N20_RS11145
uniprot id: A0A2P1S5D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

861:C4N20 RS16280
gene id: 861:C4N20_RS16280
uniprot id: A0A2P1S8B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

861:C4N20 RS16030
gene id: 861:C4N20_RS16030
uniprot id: A0A2P1S7X5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

861:C4N20 RS06710
gene id: 861:C4N20_RS06710
uniprot id: A0A2P1S2Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

861:C4N20 RS13615
gene id: 861:C4N20_RS13615
uniprot id: A0A2P1S6Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

861:C4N20 RS01430
gene id: 861:C4N20_RS01430
uniprot id: A0A2P1S039
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

861:C4N20 RS06825
gene id: 861:C4N20_RS06825
uniprot id: A0A2P1S307
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

861:C4N20 RS15225
gene id: 861:C4N20_RS15225
uniprot id: A0A2P1S7S7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

861:C4N20 RS01540
gene id: 861:C4N20_RS01540
uniprot id: A0A2P1S071
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

861:C4N20 RS03830
gene id: 861:C4N20_RS03830
uniprot id: A0A2P1S1I7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

861:C4N20 RS10980
gene id: 861:C4N20_RS10980
uniprot id: A0A2P1S588
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS13345
gene id: 861:C4N20_RS13345
uniprot id: A0A2P1S6G8
names: Similarity
messages: Belongs to the HdrA family.

861:C4N20 RS05710
gene id: 861:C4N20_RS05710
uniprot id: A0A2P1S2I8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

861:C4N20 RS06425
gene id: 861:C4N20_RS06425
uniprot id: A0A2P1S3A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

861:C4N20 RS10445
gene id: 861:C4N20_RS10445
uniprot id: A0A2P1S4Z0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

861:C4N20 RS04275
gene id: 861:C4N20_RS04275
uniprot id: A0A2P1S1M4
names: Similarity
messages: Belongs to the TlyA family.

861:C4N20 RS00470
gene id: 861:C4N20_RS00470
uniprot id: A0A2P1S051
names: Similarity
messages: Belongs to the peptidase S66 family.

861:C4N20 RS15880
gene id: 861:C4N20_RS15880
uniprot id: A0A2P1S7U3
names: Subunit
messages: Homodimer.

861:C4N20 RS01205
gene id: 861:C4N20_RS01205
uniprot id: A0A2P1S0J6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

861:C4N20 RS09610
gene id: 861:C4N20_RS09610
uniprot id: A0A2P1S4H7
names: Similarity
messages: Belongs to the peptidase C59 family.

861:C4N20 RS03485
gene id: 861:C4N20_RS03485
uniprot id: A0A2P1S184
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

861:C4N20 RS15290
gene id: 861:C4N20_RS15290
uniprot id: A0A2P1S7K9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

861:C4N20 RS02120
gene id: 861:C4N20_RS02120
uniprot id: A0A2P1S0H5
names: Similarity
messages: Belongs to the aldose epimerase family.

861:C4N20 RS06820
gene id: 861:C4N20_RS06820
uniprot id: A0A2P1S3G8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

861:C4N20 RS00430
gene id: 861:C4N20_RS00430
uniprot id: A0A2P1RZJ9
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS12560
gene id: 861:C4N20_RS12560
uniprot id: A0A2P1S643
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

861:C4N20 RS16190
gene id: 861:C4N20_RS16190
uniprot id: A0A2P1S818
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS03545
gene id: 861:C4N20_RS03545
uniprot id: A0A2P1S1P7
names: Similarity
messages: Belongs to the CdaR family.

861:C4N20 RS12115
gene id: 861:C4N20_RS12115
uniprot id: A0A2P1S5V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

861:C4N20 RS14565
gene id: 861:C4N20_RS14565
uniprot id: A0A2P1S750
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

861:C4N20 RS01695
gene id: 861:C4N20_RS01695
uniprot id: A0A2P1S090
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

861:C4N20 RS08245
gene id: 861:C4N20_RS08245
uniprot id: A0A2P1S3R9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

861:C4N20 RS02510
gene id: 861:C4N20_RS02510
uniprot id: A0A2P1S0P8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

861:C4N20 RS11480
gene id: 861:C4N20_RS11480
uniprot id: A0A2P1S5J2
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS11750
gene id: 861:C4N20_RS11750
uniprot id: A0A2P1S5M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

861:C4N20 RS07400
gene id: 861:C4N20_RS07400
uniprot id: A0A2P1S398
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

861:C4N20 RS10480
gene id: 861:C4N20_RS10480
uniprot id: A0A2P1S4Y8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS01380
gene id: 861:C4N20_RS01380
uniprot id: A0A2P1S028
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

861:C4N20 RS10100
gene id: 861:C4N20_RS10100
uniprot id: A0A2P1S4S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

861:C4N20 RS10135
gene id: 861:C4N20_RS10135
uniprot id: A0A2P1S4S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

861:C4N20 RS13210
gene id: 861:C4N20_RS13210
uniprot id: A0A2P1S6F5
names: Similarity
messages: Belongs to the ribF family.

861:C4N20 RS11095
gene id: 861:C4N20_RS11095
uniprot id: A0A2P1S5A7
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

861:C4N20 RS14310
gene id: 861:C4N20_RS14310
uniprot id: A0A2P1S704
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

861:C4N20 RS12025
gene id: 861:C4N20_RS12025
uniprot id: A0A2P1S5R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

861:C4N20 RS03275
gene id: 861:C4N20_RS03275
uniprot id: A0A2P1S173
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

861:C4N20 RS09755
gene id: 861:C4N20_RS09755
uniprot id: A0A2P1S4K7
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

861:C4N20 RS05070
gene id: 861:C4N20_RS05070
uniprot id: A0A2P1S224
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

861:C4N20 RS09380
gene id: 861:C4N20_RS09380
uniprot id: A0A2P1S4B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

861:C4N20 RS08735
gene id: 861:C4N20_RS08735
uniprot id: A0A2P1S405
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

861:C4N20 RS13555
gene id: 861:C4N20_RS13555
uniprot id: A0A2P1S6P6
names: Similarity
messages: Belongs to the MipA/OmpV family.

861:C4N20 RS08630
gene id: 861:C4N20_RS08630
uniprot id: A0A2P1S3Z9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

861:C4N20 RS15150
gene id: 861:C4N20_RS15150
uniprot id: A0A2P1S7J1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS07440
gene id: 861:C4N20_RS07440
uniprot id: A0A2P1S3F2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

861:C4N20 RS05465
gene id: 861:C4N20_RS05465
uniprot id: A0A2P1S2N5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

861:C4N20 RS01600
gene id: 861:C4N20_RS01600
uniprot id: A0A2P1S0C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

861:C4N20 RS05245
gene id: 861:C4N20_RS05245
uniprot id: A0A2P1S246
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

861:C4N20 RS16230
gene id: 861:C4N20_RS16230
uniprot id: A0A2P1S8A5
names: Similarity
messages: Belongs to the DEAD box helicase family.

861:C4N20 RS01180
gene id: 861:C4N20_RS01180
uniprot id: A0A2P1S0F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

861:C4N20 RS03575
gene id: 861:C4N20_RS03575
uniprot id: A0A2P1S1D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

861:C4N20 RS12215
gene id: 861:C4N20_RS12215
uniprot id: A0A2P1S5V7
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS15035
gene id: 861:C4N20_RS15035
uniprot id: A0A2P1S7E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

861:C4N20 RS14315
gene id: 861:C4N20_RS14315
uniprot id: A0A2P1S701
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

861:C4N20 RS06485
gene id: 861:C4N20_RS06485
uniprot id: A0A2P1S2V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

861:C4N20 RS12770
gene id: 861:C4N20_RS12770
uniprot id: A0A2P1S671
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

861:C4N20 RS06140
gene id: 861:C4N20_RS06140
uniprot id: A0A2P1S2M5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

861:C4N20 RS06875
gene id: 861:C4N20_RS06875
uniprot id: A0A2P1S317
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS05515
gene id: 861:C4N20_RS05515
uniprot id: A0A2P1S2F6
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

861:C4N20 RS14755
gene id: 861:C4N20_RS14755
uniprot id: A0A2P1S785
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

861:C4N20 RS06785
gene id: 861:C4N20_RS06785
uniprot id: A0A2P1S300
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

861:C4N20 RS10630
gene id: 861:C4N20_RS10630
uniprot id: A0A2P1S514
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

861:C4N20 RS06225
gene id: 861:C4N20_RS06225
uniprot id: A0A2P1S314
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS12630
gene id: 861:C4N20_RS12630
uniprot id: A0A2P1S640
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

861:C4N20 RS14350
gene id: 861:C4N20_RS14350
uniprot id: A0A2P1S7B2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861:C4N20 RS02200
gene id: 861:C4N20_RS02200
uniprot id: A0A2P1S0I1
names: Similarity
messages: Belongs to the RecJ family.

861:C4N20 RS11040
gene id: 861:C4N20_RS11040
uniprot id: A0A2P1S5C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

861:C4N20 RS04335
gene id: 861:C4N20_RS04335
uniprot id: A0A2P1S1R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

861:C4N20 RS07430
gene id: 861:C4N20_RS07430
uniprot id: A0A2P1S3C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
messages: Homodimer.

861:C4N20 RS12195
gene id: 861:C4N20_RS12195
uniprot id: A0A2P1S5X0
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS02935
gene id: 861:C4N20_RS02935
uniprot id: A0A2P1S116
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

861:C4N20 RS13195
gene id: 861:C4N20_RS13195
uniprot id: A0A2P1S6G0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS06720
gene id: 861:C4N20_RS06720
uniprot id: A0A2P1S2Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

861:C4N20 RS02915
gene id: 861:C4N20_RS02915
uniprot id: A0A2P1S112
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

861:C4N20 RS04840
gene id: 861:C4N20_RS04840
uniprot id: A0A2P1S1Z5
names: Similarity
messages: Belongs to the peptidase A24 family.

861:C4N20 RS15980
gene id: 861:C4N20_RS15980
uniprot id: A0A2P1S7W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

861:C4N20 RS14875
gene id: 861:C4N20_RS14875
uniprot id: A0A2P1S7A9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
messages: Belongs to the arginase family.

861:C4N20 RS04420
gene id: 861:C4N20_RS04420
uniprot id: A0A2P1S258
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

861:C4N20 RS01375
gene id: 861:C4N20_RS01375
uniprot id: A0A2P1S035
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

861:C4N20 RS07215
gene id: 861:C4N20_RS07215
uniprot id: A0A2P1S384
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS00740
gene id: 861:C4N20_RS00740
uniprot id: A0A2P1RZV2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

861:C4N20 RS12720
gene id: 861:C4N20_RS12720
uniprot id: A0A2P1S660
names: Similarity
messages: Belongs to the Nudix hydrolase family.

861:C4N20 RS07175
gene id: 861:C4N20_RS07175
uniprot id: A0A2P1S363
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS05315
gene id: 861:C4N20_RS05315
uniprot id: A0A2P1S2A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

861:C4N20 RS09895
gene id: 861:C4N20_RS09895
uniprot id: A0A2P1S540
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

861:C4N20 RS04730
gene id: 861:C4N20_RS04730
uniprot id: A0A2P1S1U5
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

861:C4N20 RS10225
gene id: 861:C4N20_RS10225
uniprot id: A0A2P1S4V0
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

861:C4N20 RS02110
gene id: 861:C4N20_RS02110
uniprot id: A0A2P1S109
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

861:C4N20 RS11800
gene id: 861:C4N20_RS11800
uniprot id: A0A2P1S5N5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

861:C4N20 RS11795
gene id: 861:C4N20_RS11795
uniprot id: A0A2P1S665
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

861:C4N20 RS00065
gene id: 861:C4N20_RS00065
uniprot id: A0A2P1RZD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

861:C4N20 RS01100
gene id: 861:C4N20_RS01100
uniprot id: A0A2P1S0H6
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

861:C4N20 RS03475
gene id: 861:C4N20_RS03475
uniprot id: A0A2P1S1B2
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

861:C4N20 RS05830
gene id: 861:C4N20_RS05830
uniprot id: A0A2P1S2G6
names: Similarity
messages: Belongs to the UxaA family.

861:C4N20 RS06125
gene id: 861:C4N20_RS06125
uniprot id: A0A2P1S2Z4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

861:C4N20 RS06110
gene id: 861:C4N20_RS06110
uniprot id: A0A2P1S2N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

861:C4N20 RS14135
gene id: 861:C4N20_RS14135
uniprot id: A0A2P1S6X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

861:C4N20 RS02885
gene id: 861:C4N20_RS02885
uniprot id: A0A2P1S108
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

861:C4N20 RS09035
gene id: 861:C4N20_RS09035
uniprot id: A0A2P1S464
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861:C4N20 RS14890
gene id: 861:C4N20_RS14890
uniprot id: A0A2P1S7E0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

861:C4N20 RS10180
gene id: 861:C4N20_RS10180
uniprot id: A0A2P1S548
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

861:C4N20 RS04365
gene id: 861:C4N20_RS04365
uniprot id: A0A2P1S1T7
names: Subcellular Location Annotation
messages: Cytoplasm

861:C4N20 RS07015
gene id: 861:C4N20_RS07015
uniprot id: A0A2P1S328
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

861:C4N20 RS11635
gene id: 861:C4N20_RS11635
uniprot id: A0A2P1S5J8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

861:C4N20 RS10555
gene id: 861:C4N20_RS10555
uniprot id: A0A2P1S519
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

861:C4N20 RS02165
gene id: 861:C4N20_RS02165
uniprot id: A0A2P1S0L8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

861:C4N20 RS03360
gene id: 861:C4N20_RS03360
uniprot id: A0A2P1S194
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

861:C4N20 RS08870
gene id: 861:C4N20_RS08870
uniprot id: A0A2P1S429
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

861:C4N20 RS01315
gene id: 861:C4N20_RS01315
uniprot id: A0A2P1S064
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

861:C4N20 RS10470
gene id: 861:C4N20_RS10470
uniprot id: A0A2P1S4X5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

861:C4N20 RS08690
gene id: 861:C4N20_RS08690
uniprot id: A0A2P1S415
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS08625
gene id: 861:C4N20_RS08625
uniprot id: A0A2P1S3Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

861:C4N20 RS03210
gene id: 861:C4N20_RS03210
uniprot id: A0A2P1S144
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

861:C4N20 RS06750
gene id: 861:C4N20_RS06750
uniprot id: A0A2P1S2X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

861:C4N20 RS08710
gene id: 861:C4N20_RS08710
uniprot id: A0A2P1S407
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

861:C4N20 RS02475
gene id: 861:C4N20_RS02475
uniprot id: A0A2P1S0P4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

861:C4N20 RS09130
gene id: 861:C4N20_RS09130
uniprot id: A0A2P1S486
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

861:C4N20 RS01475
gene id: 861:C4N20_RS01475
uniprot id: A0A2P1S054
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

861:C4N20 RS04525
gene id: 861:C4N20_RS04525
uniprot id: A0A2P1S1U1
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS15205
gene id: 861:C4N20_RS15205
uniprot id: A0A2P1S7H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

861:C4N20 RS11020
gene id: 861:C4N20_RS11020
uniprot id: A0A2P1S598
names: Similarity
messages: Belongs to the UPF0758 family.

861:C4N20 RS03790
gene id: 861:C4N20_RS03790
uniprot id: A0A2P1S1E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS10860
gene id: 861:C4N20_RS10860
uniprot id: A0A2P1S583
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

861:C4N20 RS09655
gene id: 861:C4N20_RS09655
uniprot id: A0A2P1S4I6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS02855
gene id: 861:C4N20_RS02855
uniprot id: A0A2P1S0X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

861:C4N20 RS04130
gene id: 861:C4N20_RS04130
uniprot id: A0A2P1S1M8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

861:C4N20 RS05290
gene id: 861:C4N20_RS05290
uniprot id: A0A2P1S263
names: Similarity
messages: Belongs to the RemA family.

861:C4N20 RS11210
gene id: 861:C4N20_RS11210
uniprot id: A0A2P1S5U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

861:C4N20 RS04145
gene id: 861:C4N20_RS04145
uniprot id: A0A2P1S1K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

861:C4N20 RS08555
gene id: 861:C4N20_RS08555
uniprot id: A0A2P1S3W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

861:C4N20 RS14345
gene id: 861:C4N20_RS14345
uniprot id: A0A2P1S716
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

861:C4N20 RS08955
gene id: 861:C4N20_RS08955
uniprot id: A0A2P1S4G7
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS14505
gene id: 861:C4N20_RS14505
uniprot id: A0A2P1S762
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

861:C4N20 RS13980
gene id: 861:C4N20_RS13980
uniprot id: A0A2P1S6W4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two zinc ions.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

861:C4N20 RS01145
gene id: 861:C4N20_RS01145
uniprot id: A0A2P1RZZ9
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

861:C4N20 RS13680
gene id: 861:C4N20_RS13680
uniprot id: A0A2P1S797
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

861:C4N20 RS04020
gene id: 861:C4N20_RS04020
uniprot id: A0A2P1S236
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS13205
gene id: 861:C4N20_RS13205
uniprot id: A0A2P1S6E6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

861:C4N20 RS12590
gene id: 861:C4N20_RS12590
uniprot id: A0A2P1S634
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

861:C4N20 RS08925
gene id: 861:C4N20_RS08925
uniprot id: A0A2P1S4K5
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

861:C4N20 RS07130
gene id: 861:C4N20_RS07130
uniprot id: A0A2P1S3H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS11915
gene id: 861:C4N20_RS11915
uniprot id: A0A2P1S5R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

861:C4N20 RS09285
gene id: 861:C4N20_RS09285
uniprot id: A0A2P1S4A9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

861:C4N20 RS07355
gene id: 861:C4N20_RS07355
uniprot id: A0A2P1S3A4
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

861:C4N20 RS10160
gene id: 861:C4N20_RS10160
uniprot id: A0A2P1S4U1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

861:C4N20 RS06980
gene id: 861:C4N20_RS06980
uniprot id: A0A2P1S313
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

861:C4N20 RS00060
gene id: 861:C4N20_RS00060
uniprot id: A0A2P1RZD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

861:C4N20 RS03030
gene id: 861:C4N20_RS03030
uniprot id: A0A2P1S107
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS13415
gene id: 861:C4N20_RS13415
uniprot id: A0A2P1S6J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

861:C4N20 RS06145
gene id: 861:C4N20_RS06145
uniprot id: A0A2P1S345
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

861:C4N20 RS07035
gene id: 861:C4N20_RS07035
uniprot id: A0A2P1S318
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

861:C4N20 RS02235
gene id: 861:C4N20_RS02235
uniprot id: A0A2P1S0K5
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

861:C4N20 RS14885
gene id: 861:C4N20_RS14885
uniprot id: A0A2P1S7Z9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

861:C4N20 RS13985
gene id: 861:C4N20_RS13985
uniprot id: A0A2P1S6T9
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS08385
gene id: 861:C4N20_RS08385
uniprot id: A0A2P1S3T6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861:C4N20 RS02440
gene id: 861:C4N20_RS02440
uniprot id: A0A2P1S0P6
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

861:C4N20 RS01470
gene id: 861:C4N20_RS01470
uniprot id: A0A2P1S088
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

861:C4N20 RS05310
gene id: 861:C4N20_RS05310
uniprot id: A0A2P1S290
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

861:C4N20 RS08945
gene id: 861:C4N20_RS08945
uniprot id: A0A2P1S457
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS04410
gene id: 861:C4N20_RS04410
uniprot id: A0A2P1S1R2
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

861:C4N20 RS07920
gene id: 861:C4N20_RS07920
uniprot id: A0A2P1S400
names: Similarity
messages: Belongs to the PRORSD1 family.

861:C4N20 RS16295
gene id: 861:C4N20_RS16295
uniprot id: A0A2P1S832
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

861:C4N20 RS11675
gene id: 861:C4N20_RS11675
uniprot id: A0A2P1S5M2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

861:C4N20 RS14720
gene id: 861:C4N20_RS14720
uniprot id: A0A2P1S779
names: Similarity
messages: Belongs to the pirin family.

861:C4N20 RS08660
gene id: 861:C4N20_RS08660
uniprot id: A0A2P1S3Z2
names: Similarity
messages: Belongs to the UPF0102 family.

861:C4N20 RS06250
gene id: 861:C4N20_RS06250
uniprot id: A0A2P1S2R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

861:C4N20 RS12090
gene id: 861:C4N20_RS12090
uniprot id: A0A2P1S5U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

861:C4N20 RS10945
gene id: 861:C4N20_RS10945
uniprot id: A0A2P1S5P9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

861:C4N20 RS07840
gene id: 861:C4N20_RS07840
uniprot id: A0A2P1S3J2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

861:C4N20 RS02845
gene id: 861:C4N20_RS02845
uniprot id: A0A2P1S0W0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

861:C4N20 RS04375
gene id: 861:C4N20_RS04375
uniprot id: A0A2P1S1Q6
names: Similarity
messages: Belongs to the glutamine synthetase family.

861:C4N20 RS03130
gene id: 861:C4N20_RS03130
uniprot id: A0A2P1S146
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS10540
gene id: 861:C4N20_RS10540
uniprot id: A0A2P1S4Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

861:C4N20 RS09095
gene id: 861:C4N20_RS09095
uniprot id: A0A2P1S488
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

861:C4N20 RS09685
gene id: 861:C4N20_RS09685
uniprot id: A0A2P1S4I9
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

861:C4N20 RS09090
gene id: 861:C4N20_RS09090
uniprot id: A0A2P1S474
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

861:C4N20 RS11820
gene id: 861:C4N20_RS11820
uniprot id: A0A2P1S5M5
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

861:C4N20 RS08460
gene id: 861:C4N20_RS08460
uniprot id: A0A2P1S3X3
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS05455
gene id: 861:C4N20_RS05455
uniprot id: A0A2P1S284
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

861:C4N20 RS04150
gene id: 861:C4N20_RS04150
uniprot id: A0A2P1S1P6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS01235
gene id: 861:C4N20_RS01235
uniprot id: A0A2P1S0G4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861:C4N20 RS13845
gene id: 861:C4N20_RS13845
uniprot id: A0A2P1S6S1
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

861:C4N20 RS11280
gene id: 861:C4N20_RS11280
uniprot id: A0A2P1S5F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

861:C4N20 RS13880
gene id: 861:C4N20_RS13880
uniprot id: A0A2P1S6S4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

861:C4N20 RS07280
gene id: 861:C4N20_RS07280
uniprot id: A0A2P1S383
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

861:C4N20 RS15550
gene id: 861:C4N20_RS15550
uniprot id: A0A2P1S7Y2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

861:C4N20 RS02830
gene id: 861:C4N20_RS02830
uniprot id: A0A2P1S1E5
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS03650
gene id: 861:C4N20_RS03650
uniprot id: A0A2P1S1C3
names: Function
names: Similarity
messages: Belongs to the type-2 OGG1 family.
messages: Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).

861:C4N20 RS00880
gene id: 861:C4N20_RS00880
uniprot id: A0A2P1RZU7
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

861:C4N20 RS05195
gene id: 861:C4N20_RS05195
uniprot id: A0A2P1S232
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS07250
gene id: 861:C4N20_RS07250
uniprot id: A0A2P1S360
names: Similarity
messages: Belongs to the glutathione peroxidase family.

861:C4N20 RS07285
gene id: 861:C4N20_RS07285
uniprot id: A0A2P1S3C6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

861:C4N20 RS02375
gene id: 861:C4N20_RS02375
uniprot id: A0A2P1S0M6
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS00040
gene id: 861:C4N20_RS00040
uniprot id: A0A2P1RZB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

861:C4N20 RS02280
gene id: 861:C4N20_RS02280
uniprot id: A0A2P1S0K2
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

861:C4N20 RS10520
gene id: 861:C4N20_RS10520
uniprot id: A0A2P1S524
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

861:C4N20 RS08720
gene id: 861:C4N20_RS08720
uniprot id: A0A2P1S403
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

861:C4N20 RS07675
gene id: 861:C4N20_RS07675
uniprot id: A0A2P1S3I8
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

861:C4N20 RS01110
gene id: 861:C4N20_RS01110
uniprot id: A0A2P1RZY0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

861:C4N20 RS09515
gene id: 861:C4N20_RS09515
uniprot id: A0A2P1S4I3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

861:C4N20 RS08830
gene id: 861:C4N20_RS08830
uniprot id: A0A2P1S420
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

861:C4N20 RS06795
gene id: 861:C4N20_RS06795
uniprot id: A0A2P1S343
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

861:C4N20 RS06865
gene id: 861:C4N20_RS06865
uniprot id: A0A2P1S311
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

861:C4N20 RS04460
gene id: 861:C4N20_RS04460
uniprot id: A0A2P1S1S4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

861:C4N20 RS06815
gene id: 861:C4N20_RS06815
uniprot id: A0A2P1S301
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

861:C4N20 RS12565
gene id: 861:C4N20_RS12565
uniprot id: A0A2P1S629
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

861:C4N20 RS09310
gene id: 861:C4N20_RS09310
uniprot id: A0A2P1S899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

861:C4N20 RS04265
gene id: 861:C4N20_RS04265
uniprot id: A0A2P1S233
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

861:C4N20 RS06690
gene id: 861:C4N20_RS06690
uniprot id: A0A2P1S326
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

861:C4N20 RS11640
gene id: 861:C4N20_RS11640
uniprot id: A0A2P1S618
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS10695
gene id: 861:C4N20_RS10695
uniprot id: A0A2P1S539
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861:C4N20 RS14630
gene id: 861:C4N20_RS14630
uniprot id: A0A2P1S776
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

861:C4N20 RS11540
gene id: 861:C4N20_RS11540
uniprot id: A0A2P1S5J4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS05140
gene id: 861:C4N20_RS05140
uniprot id: A0A2P1S238
names: Similarity
messages: Belongs to the pyruvate kinase family.

861:C4N20 RS11045
gene id: 861:C4N20_RS11045
uniprot id: A0A2P1S5A0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

861:C4N20 RS01210
gene id: 861:C4N20_RS01210
uniprot id: A0A2P1S042
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

861:C4N20 RS13530
gene id: 861:C4N20_RS13530
uniprot id: A0A2P1S6N1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS01545
gene id: 861:C4N20_RS01545
uniprot id: A0A2P1S0M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

861:C4N20 RS16260
gene id: 861:C4N20_RS16260
uniprot id: A0A2P1S838
names: Similarity
messages: Belongs to the Dps family.

861:C4N20 RS09695
gene id: 861:C4N20_RS09695
uniprot id: A0A2P1S4I7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

861:C4N20 RS15345
gene id: 861:C4N20_RS15345
uniprot id: A0A2P1S7J5
names: Similarity
messages: Belongs to the RutC family.

861:C4N20 RS15535
gene id: 861:C4N20_RS15535
uniprot id: A0A2P1S7P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS13460
gene id: 861:C4N20_RS13460
uniprot id: A0A2P1S6K5
names: Similarity
messages: Belongs to the GARS family.

861:C4N20 RS16015
gene id: 861:C4N20_RS16015
uniprot id: A0A2P1S7Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS15555
gene id: 861:C4N20_RS15555
uniprot id: A0A2P1S7Q3
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

861:C4N20 RS10175
gene id: 861:C4N20_RS10175
uniprot id: A0A2P1S4T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

861:C4N20 RS11925
gene id: 861:C4N20_RS11925
uniprot id: A0A2P1S613
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

861:C4N20 RS06685
gene id: 861:C4N20_RS06685
uniprot id: A0A2P1S2W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

861:C4N20 RS01415
gene id: 861:C4N20_RS01415
uniprot id: A0A2P1S0N5
names: Similarity
messages: Belongs to the UPF0246 family.

861:C4N20 RS12165
gene id: 861:C4N20_RS12165
uniprot id: A0A2P1S5V1
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS06650
gene id: 861:C4N20_RS06650
uniprot id: A0A2P1S2U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

861:C4N20 RS13970
gene id: 861:C4N20_RS13970
uniprot id: A0A2P1S6U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

861:C4N20 RS13835
gene id: 861:C4N20_RS13835
uniprot id: A0A2P1S6S6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS00505
gene id: 861:C4N20_RS00505
uniprot id: A0A2P1RZM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

861:C4N20 RS02455
gene id: 861:C4N20_RS02455
uniprot id: A0A2P1S0N3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

861:C4N20 RS12505
gene id: 861:C4N20_RS12505
uniprot id: A0A2P1S6A9
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

861:C4N20 RS12130
gene id: 861:C4N20_RS12130
uniprot id: A0A2P1S651
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

861:C4N20 RS07650
gene id: 861:C4N20_RS07650
uniprot id: A0A2P1S3V2
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS03525
gene id: 861:C4N20_RS03525
uniprot id: A0A2P1S1C4
names: Similarity
messages: Belongs to the DapA family.

861:C4N20 RS11665
gene id: 861:C4N20_RS11665
uniprot id: A0A2P1S5J7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

861:C4N20 RS05225
gene id: 861:C4N20_RS05225
uniprot id: A0A2P1S239
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family. NanA subfamily.
messages: Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
messages: Cytoplasm
messages: Homotetramer.

861:C4N20 RS05275
gene id: 861:C4N20_RS05275
uniprot id: A0A2P1S251
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

861:C4N20 RS03480
gene id: 861:C4N20_RS03480
uniprot id: A0A2P1S187
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

861:C4N20 RS13535
gene id: 861:C4N20_RS13535
uniprot id: A0A2P1S6M4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS02465
gene id: 861:C4N20_RS02465
uniprot id: A0A2P1S171
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

861:C4N20 RS16215
gene id: 861:C4N20_RS16215
uniprot id: A0A2P1S828
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

861:C4N20 RS12105
gene id: 861:C4N20_RS12105
uniprot id: A0A2P1S5U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

861:C4N20 RS03550
gene id: 861:C4N20_RS03550
uniprot id: A0A2P1S1B0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861:C4N20 RS06970
gene id: 861:C4N20_RS06970
uniprot id: A0A2P1S372
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

861:C4N20 RS11005
gene id: 861:C4N20_RS11005
uniprot id: A0A2P1S5Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

861:C4N20 RS04370
gene id: 861:C4N20_RS04370
uniprot id: A0A2P1S253
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

861:C4N20 RS04515
gene id: 861:C4N20_RS04515
uniprot id: A0A2P1S1U7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

861:C4N20 RS12150
gene id: 861:C4N20_RS12150
uniprot id: A0A2P1S6D8
names: Similarity
messages: Belongs to the MlaA family.

861:C4N20 RS01335
gene id: 861:C4N20_RS01335
uniprot id: A0A2P1S032
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

861:C4N20 RS13805
gene id: 861:C4N20_RS13805
uniprot id: A0A2P1S8C8
names: Similarity
messages: Belongs to the RlpA family.

861:C4N20 RS09505
gene id: 861:C4N20_RS09505
uniprot id: A0A2P1S4F7
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS10565
gene id: 861:C4N20_RS10565
uniprot id: A0A2P1S5B8
names: Caution
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS02955
gene id: 861:C4N20_RS02955
uniprot id: A0A2P1S875
names: Similarity
messages: Belongs to the IMPACT family.

861:C4N20 RS12550
gene id: 861:C4N20_RS12550
uniprot id: A0A2P1S631
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

861:C4N20 RS13285
gene id: 861:C4N20_RS13285
uniprot id: A0A2P1S6Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS06130
gene id: 861:C4N20_RS06130
uniprot id: A0A2P1S2L8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

861:C4N20 RS16385
gene id: 861:C4N20_RS16385
uniprot id: A0A2P1S8D4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

861:C4N20 RS04325
gene id: 861:C4N20_RS04325
uniprot id: A0A2P1S1P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

861:C4N20 RS15935
gene id: 861:C4N20_RS15935
uniprot id: A0A2P1S7W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

861:C4N20 RS06015
gene id: 861:C4N20_RS06015
uniprot id: A0A2P1S2P9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

861:C4N20 RS15865
gene id: 861:C4N20_RS15865
uniprot id: A0A2P1S7V7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

861:C4N20 RS00030
gene id: 861:C4N20_RS00030
uniprot id: A0A2P1RZT3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

861:C4N20 RS00955
gene id: 861:C4N20_RS00955
uniprot id: A0A2P1RZU9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS01125
gene id: 861:C4N20_RS01125
uniprot id: A0A2P1RZZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

861:C4N20 RS04075
gene id: 861:C4N20_RS04075
uniprot id: A0A2P1S247
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS07420
gene id: 861:C4N20_RS07420
uniprot id: A0A2P1S3B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

861:C4N20 RS13430
gene id: 861:C4N20_RS13430
uniprot id: A0A2P1S6J3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

861:C4N20 RS10560
gene id: 861:C4N20_RS10560
uniprot id: A0A2P1S510
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

861:C4N20 RS04270
gene id: 861:C4N20_RS04270
uniprot id: A0A2P1S1N9
names: Similarity
messages: Belongs to the peptidase S41A family.

861:C4N20 RS09435
gene id: 861:C4N20_RS09435
uniprot id: A0A2P1S4V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

861:C4N20 RS12915
gene id: 861:C4N20_RS12915
uniprot id: A0A2P1S698
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

861:C4N20 RS09080
gene id: 861:C4N20_RS09080
uniprot id: A0A2P1S478
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

861:C4N20 RS05300
gene id: 861:C4N20_RS05300
uniprot id: A0A2P1S269
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

861:C4N20 RS07725
gene id: 861:C4N20_RS07725
uniprot id: A0A2P1S3K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

861:C4N20 RS06660
gene id: 861:C4N20_RS06660
uniprot id: A0A2P1S2X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

861:C4N20 RS04530
gene id: 861:C4N20_RS04530
uniprot id: A0A2P1S1T1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

861:C4N20 RS03805
gene id: 861:C4N20_RS03805
uniprot id: A0A2P1S1F7
names: Similarity
messages: Belongs to the CinA family.

861:C4N20 RS09425
gene id: 861:C4N20_RS09425
uniprot id: A0A2P1S4D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

861:C4N20 RS10955
gene id: 861:C4N20_RS10955
uniprot id: A0A2P1S595
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS15915
gene id: 861:C4N20_RS15915
uniprot id: A0A2P1S7W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

861:C4N20 RS10625
gene id: 861:C4N20_RS10625
uniprot id: A0A2P1S511
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

861:C4N20 RS03780
gene id: 861:C4N20_RS03780
uniprot id: A0A2P1S1H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS09865
gene id: 861:C4N20_RS09865
uniprot id: A0A2P1S4N1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

861:C4N20 RS07810
gene id: 861:C4N20_RS07810
uniprot id: A0A2P1S3F7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS08315
gene id: 861:C4N20_RS08315
uniprot id: A0A2P1S3V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS05535
gene id: 861:C4N20_RS05535
uniprot id: A0A2P1S2B7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS10800
gene id: 861:C4N20_RS10800
uniprot id: A0A2P1S558
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

861:C4N20 RS02590
gene id: 861:C4N20_RS02590
uniprot id: A0A2P1S0S7
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS09050
gene id: 861:C4N20_RS09050
uniprot id: A0A2P1S493
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS01405
gene id: 861:C4N20_RS01405
uniprot id: A0A2P1S031
names: Similarity
messages: Belongs to the peptidase M16 family.

861:C4N20 RS02815
gene id: 861:C4N20_RS02815
uniprot id: A0A2P1S0Z6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

861:C4N20 RS11190
gene id: 861:C4N20_RS11190
uniprot id: A0A2P1S5P1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

861:C4N20 RS01700
gene id: 861:C4N20_RS01700
uniprot id: A0A2P1S0A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

861:C4N20 RS07935
gene id: 861:C4N20_RS07935
uniprot id: A0A2P1S3L0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861:C4N20 RS14090
gene id: 861:C4N20_RS14090
uniprot id: A0A2P1S6Y6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS11590
gene id: 861:C4N20_RS11590
uniprot id: A0A2P1S612
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

861:C4N20 RS11100
gene id: 861:C4N20_RS11100
uniprot id: A0A2P1S599
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

861:C4N20 RS05285
gene id: 861:C4N20_RS05285
uniprot id: A0A2P1S2L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

861:C4N20 RS05155
gene id: 861:C4N20_RS05155
uniprot id: A0A2P1S2M0
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS01675
gene id: 861:C4N20_RS01675
uniprot id: A0A2P1S0T5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

861:C4N20 RS03565
gene id: 861:C4N20_RS03565
uniprot id: A0A2P1S1U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

861:C4N20 RS03725
gene id: 861:C4N20_RS03725
uniprot id: A0A2P1S1G7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

861:C4N20 RS06655
gene id: 861:C4N20_RS06655
uniprot id: A0A2P1S2U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

861:C4N20 RS14545
gene id: 861:C4N20_RS14545
uniprot id: A0A2P1S752
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

861:C4N20 RS12860
gene id: 861:C4N20_RS12860
uniprot id: A0A2P1S693
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS11000
gene id: 861:C4N20_RS11000
uniprot id: A0A2P1S581
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

861:C4N20 RS11080
gene id: 861:C4N20_RS11080
uniprot id: A0A2P1S5A5
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS09885
gene id: 861:C4N20_RS09885
uniprot id: A0A2P1S4N0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

861:C4N20 RS02215
gene id: 861:C4N20_RS02215
uniprot id: A0A2P1S0N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

861:C4N20 RS03645
gene id: 861:C4N20_RS03645
uniprot id: A0A2P1S1R7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

861:C4N20 RS05220
gene id: 861:C4N20_RS05220
uniprot id: A0A2P1S252
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

861:C4N20 RS00525
gene id: 861:C4N20_RS00525
uniprot id: A0A2P1RZN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

861:C4N20 RS03390
gene id: 861:C4N20_RS03390
uniprot id: A0A2P1S1M0
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS00725
gene id: 861:C4N20_RS00725
uniprot id: A0A2P1RZQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

861:C4N20 RS06330
gene id: 861:C4N20_RS06330
uniprot id: A0A2P1S2V8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS07040
gene id: 861:C4N20_RS07040
uniprot id: A0A2P1S348
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

861:C4N20 RS11655
gene id: 861:C4N20_RS11655
uniprot id: A0A2P1S5L9
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

861:C4N20 RS14775
gene id: 861:C4N20_RS14775
uniprot id: A0A2P1S794
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS06540
gene id: 861:C4N20_RS06540
uniprot id: A0A2P1S2W7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

861:C4N20 RS15545
gene id: 861:C4N20_RS15545
uniprot id: A0A2P1S7P9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

861:C4N20 RS06105
gene id: 861:C4N20_RS06105
uniprot id: A0A2P1S2P4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

861:C4N20 RS05025
gene id: 861:C4N20_RS05025
uniprot id: A0A2P1S211
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

861:C4N20 RS06695
gene id: 861:C4N20_RS06695
uniprot id: A0A2P1S388
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

861:C4N20 RS12140
gene id: 861:C4N20_RS12140
uniprot id: A0A2P1S5V9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS04725
gene id: 861:C4N20_RS04725
uniprot id: A0A2P1S1X4
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

861:C4N20 RS06395
gene id: 861:C4N20_RS06395
uniprot id: A0A2P1S2R7
names: Similarity
messages: Belongs to the alkaline phosphatase family.

861:C4N20 RS02670
gene id: 861:C4N20_RS02670
uniprot id: A0A2P1S0S1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

861:C4N20 RS00420
gene id: 861:C4N20_RS00420
uniprot id: A0A2P1RZN8
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

861:C4N20 RS10510
gene id: 861:C4N20_RS10510
uniprot id: A0A2P1S500
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

861:C4N20 RS13230
gene id: 861:C4N20_RS13230
uniprot id: A0A2P1S6P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

861:C4N20 RS13960
gene id: 861:C4N20_RS13960
uniprot id: A0A2P1S6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

861:C4N20 RS16010
gene id: 861:C4N20_RS16010
uniprot id: A0A2P1S807
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS16110
gene id: 861:C4N20_RS16110
uniprot id: A0A2P1S835
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

861:C4N20 RS07115
gene id: 861:C4N20_RS07115
uniprot id: A0A2P1S366
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS09055
gene id: 861:C4N20_RS09055
uniprot id: A0A2P1S4I5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

861:C4N20 RS15430
gene id: 861:C4N20_RS15430
uniprot id: A0A2P1S7K7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

861:C4N20 RS00795
gene id: 861:C4N20_RS00795
uniprot id: A0A2P1RZR8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS02460
gene id: 861:C4N20_RS02460
uniprot id: A0A2P1S0N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

861:C4N20 RS11620
gene id: 861:C4N20_RS11620
uniprot id: A0A2P1S5V8
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

861:C4N20 RS07740
gene id: 861:C4N20_RS07740
uniprot id: A0A2P1S3E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

861:C4N20 RS09315
gene id: 861:C4N20_RS09315
uniprot id: A0A2P1S4M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

861:C4N20 RS06200
gene id: 861:C4N20_RS06200
uniprot id: A0A2P1S2Q0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

861:C4N20 RS02975
gene id: 861:C4N20_RS02975
uniprot id: A0A2P1S0Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS14965
gene id: 861:C4N20_RS14965
uniprot id: A0A2P1S7N0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS11265
gene id: 861:C4N20_RS11265
uniprot id: A0A2P1S5C6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

861:C4N20 RS14590
gene id: 861:C4N20_RS14590
uniprot id: A0A2P1S784
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

861:C4N20 RS01220
gene id: 861:C4N20_RS01220
uniprot id: A0A2P1RZZ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

861:C4N20 RS14375
gene id: 861:C4N20_RS14375
uniprot id: A0A2P1S726
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

861:C4N20 RS00455
gene id: 861:C4N20_RS00455
uniprot id: A0A2P1RZP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

861:C4N20 RS10680
gene id: 861:C4N20_RS10680
uniprot id: A0A2P1S526
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861:C4N20 RS09445
gene id: 861:C4N20_RS09445
uniprot id: A0A2P1S4E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

861:C4N20 RS10580
gene id: 861:C4N20_RS10580
uniprot id: A0A2P1S506
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

861:C4N20 RS05680
gene id: 861:C4N20_RS05680
uniprot id: A0A2P1S2E3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

861:C4N20 RS06850
gene id: 861:C4N20_RS06850
uniprot id: A0A2P1S3C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

861:C4N20 RS07625
gene id: 861:C4N20_RS07625
uniprot id: A0A2P1S3I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS06880
gene id: 861:C4N20_RS06880
uniprot id: A0A2P1S325
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

861:C4N20 RS00520
gene id: 861:C4N20_RS00520
uniprot id: A0A2P1RZL3
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS00975
gene id: 861:C4N20_RS00975
uniprot id: A0A2P1RZZ2
names: Similarity
messages: Belongs to the peptidase S49 family.

861:C4N20 RS15505
gene id: 861:C4N20_RS15505
uniprot id: A0A2P1S7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

861:C4N20 RS12010
gene id: 861:C4N20_RS12010
uniprot id: A0A2P1S5S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

861:C4N20 RS13165
gene id: 861:C4N20_RS13165
uniprot id: A0A2P1S6G1
names: Similarity
messages: Belongs to the UPF0251 family.

861:C4N20 RS11850
gene id: 861:C4N20_RS11850
uniprot id: A0A2P1S5P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

861:C4N20 RS09495
gene id: 861:C4N20_RS09495
uniprot id: A0A2P1S8I2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

861:C4N20 RS05575
gene id: 861:C4N20_RS05575
uniprot id: A0A2P1S2B9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS04810
gene id: 861:C4N20_RS04810
uniprot id: A0A2P1S1Z1
names: Similarity
messages: Belongs to the bacterial secretin family.

861:C4N20 RS05380
gene id: 861:C4N20_RS05380
uniprot id: A0A2P1S2Q6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS09320
gene id: 861:C4N20_RS09320
uniprot id: A0A2P1S4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

861:C4N20 RS06135
gene id: 861:C4N20_RS06135
uniprot id: A0A2P1S2K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

861:C4N20 RS06800
gene id: 861:C4N20_RS06800
uniprot id: A0A2P1S3B0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

861:C4N20 RS07200
gene id: 861:C4N20_RS07200
uniprot id: A0A2P1S376
names: Cofactor
messages: Binds 1 zinc ion per subunit.

861:C4N20 RS09590
gene id: 861:C4N20_RS09590
uniprot id: A0A2P1S4Y5
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

861:C4N20 RS14320
gene id: 861:C4N20_RS14320
uniprot id: A0A2P1S7N9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861:C4N20 RS12375
gene id: 861:C4N20_RS12375
uniprot id: A0A2P1S5Z9
names: Similarity
messages: Belongs to the peptidase S14 family.

861:C4N20 RS04090
gene id: 861:C4N20_RS04090
uniprot id: A0A2P1S1K1
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

861:C4N20 RS05030
gene id: 861:C4N20_RS05030
uniprot id: A0A2P1S259
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS08635
gene id: 861:C4N20_RS08635
uniprot id: A0A2P1S8A8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

861:C4N20 RS13185
gene id: 861:C4N20_RS13185
uniprot id: A0A2P1S6H3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS14745
gene id: 861:C4N20_RS14745
uniprot id: A0A2P1S792
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

861:C4N20 RS12995
gene id: 861:C4N20_RS12995
uniprot id: A0A2P1S6W7
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS12110
gene id: 861:C4N20_RS12110
uniprot id: A0A2P1S5T9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

861:C4N20 RS10220
gene id: 861:C4N20_RS10220
uniprot id: A0A2P1S4V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

861:C4N20 RS14115
gene id: 861:C4N20_RS14115
uniprot id: A0A2P1S6W8
names: Similarity
messages: Belongs to the UPF0735 family.

861:C4N20 RS02655
gene id: 861:C4N20_RS02655
uniprot id: A0A2P1S0T8
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS05305
gene id: 861:C4N20_RS05305
uniprot id: A0A2P1S2P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

861:C4N20 RS00085
gene id: 861:C4N20_RS00085
uniprot id: A0A2P1RZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

861:C4N20 RS06790
gene id: 861:C4N20_RS06790
uniprot id: A0A2P1S2Y1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

861:C4N20 RS09880
gene id: 861:C4N20_RS09880
uniprot id: A0A2P1S4N5
names: Similarity
messages: Belongs to the FBPase class 3 family.

861:C4N20 RS16225
gene id: 861:C4N20_RS16225
uniprot id: A0A2P1S822
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

861:C4N20 RS07485
gene id: 861:C4N20_RS07485
uniprot id: A0A2P1S3A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

861:C4N20 RS14120
gene id: 861:C4N20_RS14120
uniprot id: A0A2P1S6Z3
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS10830
gene id: 861:C4N20_RS10830
uniprot id: A0A2P1S553
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS06915
gene id: 861:C4N20_RS06915
uniprot id: A0A2P1S322
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

861:C4N20 RS06740
gene id: 861:C4N20_RS06740
uniprot id: A0A2P1S337
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

861:C4N20 RS04425
gene id: 861:C4N20_RS04425
uniprot id: A0A2P1S1R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS04900
gene id: 861:C4N20_RS04900
uniprot id: A0A2P1S218
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS10245
gene id: 861:C4N20_RS10245
uniprot id: A0A2P1S4U8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

861:C4N20 RS13200
gene id: 861:C4N20_RS13200
uniprot id: A0A2P1S707
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

861:C4N20 RS03820
gene id: 861:C4N20_RS03820
uniprot id: A0A2P1S1Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

861:C4N20 RS16060
gene id: 861:C4N20_RS16060
uniprot id: A0A2P1S817
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

861:C4N20 RS05865
gene id: 861:C4N20_RS05865
uniprot id: A0A2P1S2V0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

861:C4N20 RS02300
gene id: 861:C4N20_RS02300
uniprot id: A0A2P1S0K3
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

861:C4N20 RS01365
gene id: 861:C4N20_RS01365
uniprot id: A0A2P1S0M5
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS02390
gene id: 861:C4N20_RS02390
uniprot id: A0A2P1S0N6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

861:C4N20 RS06270
gene id: 861:C4N20_RS06270
uniprot id: A0A2P1S2U6
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

861:C4N20 RS15420
gene id: 861:C4N20_RS15420
uniprot id: A0A2P1S893
names: Similarity
messages: Belongs to the class-I fumarase family.

861:C4N20 RS15475
gene id: 861:C4N20_RS15475
uniprot id: A0A2P1S7P5
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

861:C4N20 RS11350
gene id: 861:C4N20_RS11350
uniprot id: A0A2P1S5S2
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

861:C4N20 RS03640
gene id: 861:C4N20_RS03640
uniprot id: A0A2P1S1F1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

861:C4N20 RS08075
gene id: 861:C4N20_RS08075
uniprot id: A0A2P1S427
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS03140
gene id: 861:C4N20_RS03140
uniprot id: A0A2P1S123
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

861:C4N20 RS10805
gene id: 861:C4N20_RS10805
uniprot id: A0A2P1S563
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

861:C4N20 RS14460
gene id: 861:C4N20_RS14460
uniprot id: A0A2P1S731
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

861:C4N20 RS12580
gene id: 861:C4N20_RS12580
uniprot id: A0A2P1S627
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS12700
gene id: 861:C4N20_RS12700
uniprot id: A0A2P1S659
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

861:C4N20 RS13160
gene id: 861:C4N20_RS13160
uniprot id: A0A2P1S6E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

861:C4N20 RS10310
gene id: 861:C4N20_RS10310
uniprot id: A0A2P1S4W1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861:C4N20 RS01340
gene id: 861:C4N20_RS01340
uniprot id: A0A2P1S0I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

861:C4N20 RS02500
gene id: 861:C4N20_RS02500
uniprot id: A0A2P1S0T6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

861:C4N20 RS03420
gene id: 861:C4N20_RS03420
uniprot id: A0A2P1S1A1
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

861:C4N20 RS07560
gene id: 861:C4N20_RS07560
uniprot id: A0A2P1S3E1
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

861:C4N20 RS02325
gene id: 861:C4N20_RS02325
uniprot id: A0A2P1S0L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

861:C4N20 RS08340
gene id: 861:C4N20_RS08340
uniprot id: A0A2P1S487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

861:C4N20 RS10500
gene id: 861:C4N20_RS10500
uniprot id: A0A2P1S502
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

861:C4N20 RS00780
gene id: 861:C4N20_RS00780
uniprot id: A0A2P1RZS9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS10905
gene id: 861:C4N20_RS10905
uniprot id: A0A2P1S587
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

861:C4N20 RS04125
gene id: 861:C4N20_RS04125
uniprot id: A0A2P1S255
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

861:C4N20 RS05065
gene id: 861:C4N20_RS05065
uniprot id: A0A2P1S267
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

861:C4N20 RS06675
gene id: 861:C4N20_RS06675
uniprot id: A0A2P1S2Y8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

861:C4N20 RS06120
gene id: 861:C4N20_RS06120
uniprot id: A0A2P1S2S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

861:C4N20 RS14365
gene id: 861:C4N20_RS14365
uniprot id: A0A2P1S710
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

861:C4N20 RS06025
gene id: 861:C4N20_RS06025
uniprot id: A0A2P1S2J7
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

861:C4N20 RS01160
gene id: 861:C4N20_RS01160
uniprot id: A0A2P1RZZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

861:C4N20 RS08535
gene id: 861:C4N20_RS08535
uniprot id: A0A2P1S3X7
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

861:C4N20 RS02420
gene id: 861:C4N20_RS02420
uniprot id: A0A2P1S0S2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

861:C4N20 RS05730
gene id: 861:C4N20_RS05730
uniprot id: A0A2P1S2F0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS08920
gene id: 861:C4N20_RS08920
uniprot id: A0A2P1S438
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

861:C4N20 RS04880
gene id: 861:C4N20_RS04880
uniprot id: A0A2P1S203
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS13625
gene id: 861:C4N20_RS13625
uniprot id: A0A2P1S6M8
names: Similarity
messages: Belongs to the UPF0145 family.

861:C4N20 RS00665
gene id: 861:C4N20_RS00665
uniprot id: A0A2P1S047
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS13035
gene id: 861:C4N20_RS13035
uniprot id: A0A2P1S6C3
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS11790
gene id: 861:C4N20_RS11790
uniprot id: A0A2P1S5M3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

861:C4N20 RS06975
gene id: 861:C4N20_RS06975
uniprot id: A0A2P1S3D9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

861:C4N20 RS06055
gene id: 861:C4N20_RS06055
uniprot id: A0A2P1S2N7
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS13180
gene id: 861:C4N20_RS13180
uniprot id: A0A2P1S6N4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS06280
gene id: 861:C4N20_RS06280
uniprot id: A0A2P1S2P8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

861:C4N20 RS00075
gene id: 861:C4N20_RS00075
uniprot id: A0A2P1RZE5
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS07615
gene id: 861:C4N20_RS07615
uniprot id: A0A2P1S3F3
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

861:C4N20 RS01650
gene id: 861:C4N20_RS01650
uniprot id: A0A2P1S0D2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS00045
gene id: 861:C4N20_RS00045
uniprot id: A0A2P1RZE4
names: Similarity
messages: Belongs to the Skp family.

861:C4N20 RS14865
gene id: 861:C4N20_RS14865
uniprot id: A0A2P1S7K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

861:C4N20 RS09715
gene id: 861:C4N20_RS09715
uniprot id: A0A2P1S4M1
names: Similarity
messages: Belongs to the RutC family.

861:C4N20 RS04560
gene id: 861:C4N20_RS04560
uniprot id: A0A2P1S1U8
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

861:C4N20 RS05820
gene id: 861:C4N20_RS05820
uniprot id: A0A2P1S2F9
names: Similarity
messages: Belongs to the DapA family.

861:C4N20 RS03690
gene id: 861:C4N20_RS03690
uniprot id: A0A2P1S1G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS08495
gene id: 861:C4N20_RS08495
uniprot id: A0A2P1S4C1
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

861:C4N20 RS14600
gene id: 861:C4N20_RS14600
uniprot id: A0A2P1S7F3
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS10255
gene id: 861:C4N20_RS10255
uniprot id: A0A2P1S4U6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

861:C4N20 RS09150
gene id: 861:C4N20_RS09150
uniprot id: A0A2P1S4A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

861:C4N20 RS10270
gene id: 861:C4N20_RS10270
uniprot id: A0A2P1S4W6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

861:C4N20 RS04715
gene id: 861:C4N20_RS04715
uniprot id: A0A2P1S1Z9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

861:C4N20 RS06670
gene id: 861:C4N20_RS06670
uniprot id: A0A2P1S2Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

861:C4N20 RS10165
gene id: 861:C4N20_RS10165
uniprot id: A0A2P1S4U4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

861:C4N20 RS08355
gene id: 861:C4N20_RS08355
uniprot id: A0A2P1S3T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS04735
gene id: 861:C4N20_RS04735
uniprot id: A0A2P1S1Y5
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS16140
gene id: 861:C4N20_RS16140
uniprot id: A0A2P1S8M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

861:C4N20 RS12500
gene id: 861:C4N20_RS12500
uniprot id: A0A2P1S624
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

861:C4N20 RS05585
gene id: 861:C4N20_RS05585
uniprot id: A0A2P1S2E0
names: Similarity
messages: Belongs to the peptidase S13 family.

861:C4N20 RS06335
gene id: 861:C4N20_RS06335
uniprot id: A0A2P1S332
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS15890
gene id: 861:C4N20_RS15890
uniprot id: A0A2P1S8I3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

861:C4N20 RS14920
gene id: 861:C4N20_RS14920
uniprot id: A0A2P1S7D6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS06730
gene id: 861:C4N20_RS06730
uniprot id: A0A2P1S2Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

861:C4N20 RS01195
gene id: 861:C4N20_RS01195
uniprot id: A0A2P1RZZ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

861:C4N20 RS06635
gene id: 861:C4N20_RS06635
uniprot id: A0A2P1S2V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

861:C4N20 RS12790
gene id: 861:C4N20_RS12790
uniprot id: A0A2P1S672
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS11420
gene id: 861:C4N20_RS11420
uniprot id: A0A2P1S5G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

861:C4N20 RS04055
gene id: 861:C4N20_RS04055
uniprot id: A0A2P1S1Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

861:C4N20 RS00460
gene id: 861:C4N20_RS00460
uniprot id: A0A2P1RZK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

861:C4N20 RS05615
gene id: 861:C4N20_RS05615
uniprot id: A0A2P1S2D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

861:C4N20 RS05945
gene id: 861:C4N20_RS05945
uniprot id: A0A2P1S2K0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

861:C4N20 RS08500
gene id: 861:C4N20_RS08500
uniprot id: A0A2P1S3V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS12785
gene id: 861:C4N20_RS12785
uniprot id: A0A2P1S666
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

861:C4N20 RS11835
gene id: 861:C4N20_RS11835
uniprot id: A0A2P1S5P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

861:C4N20 RS14105
gene id: 861:C4N20_RS14105
uniprot id: A0A2P1S7K2
names: Similarity
messages: Belongs to the threonine synthase family.

861:C4N20 RS07380
gene id: 861:C4N20_RS07380
uniprot id: A0A2P1S3B2
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

861:C4N20 RS10130
gene id: 861:C4N20_RS10130
uniprot id: A0A2P1S4V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

861:C4N20 RS01995
gene id: 861:C4N20_RS01995
uniprot id: A0A2P1S0D7
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

861:C4N20 RS10035
gene id: 861:C4N20_RS10035
uniprot id: A0A2P1S4Q9
names: Subcellular Location Annotation
messages: Cytoplasm

861:C4N20 RS01070
gene id: 861:C4N20_RS01070
uniprot id: A0A2P1RZY5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

861:C4N20 RS07300
gene id: 861:C4N20_RS07300
uniprot id: A0A2P1S369
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

861:C4N20 RS14860
gene id: 861:C4N20_RS14860
uniprot id: A0A2P1S7A3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

861:C4N20 RS01020
gene id: 861:C4N20_RS01020
uniprot id: A0A2P1RZX5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

861:C4N20 RS10460
gene id: 861:C4N20_RS10460
uniprot id: A0A2P1S5A1
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS08565
gene id: 861:C4N20_RS08565
uniprot id: A0A2P1S3X6
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS02765
gene id: 861:C4N20_RS02765
uniprot id: A0A2P1S0Y7
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

861:C4N20 RS10940
gene id: 861:C4N20_RS10940
uniprot id: A0A2P1S573
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

861:C4N20 RS09545
gene id: 861:C4N20_RS09545
uniprot id: A0A2P1S4F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS09490
gene id: 861:C4N20_RS09490
uniprot id: A0A2P1S4E4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

861:C4N20 RS00635
gene id: 861:C4N20_RS00635
uniprot id: A0A2P1S085
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS09375
gene id: 861:C4N20_RS09375
uniprot id: A0A2P1S4C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

861:C4N20 RS12955
gene id: 861:C4N20_RS12955
uniprot id: A0A2P1S6B4
names: Subcellular Location Annotation
messages: Cytoplasm

861:C4N20 RS03500
gene id: 861:C4N20_RS03500
uniprot id: A0A2P1S1A0
names: Similarity
messages: Belongs to the peptidase M20A family.

861:C4N20 RS04255
gene id: 861:C4N20_RS04255
uniprot id: A0A2P1S1N5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS01200
gene id: 861:C4N20_RS01200
uniprot id: A0A2P1S009
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

861:C4N20 RS13065
gene id: 861:C4N20_RS13065
uniprot id: A0A2P1S6E2
names: Similarity
messages: Belongs to the LarC family.

861:C4N20 RS03625
gene id: 861:C4N20_RS03625
uniprot id: A0A2P1S1E2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS06705
gene id: 861:C4N20_RS06705
uniprot id: A0A2P1S2W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

861:C4N20 RS08650
gene id: 861:C4N20_RS08650
uniprot id: A0A2P1S8B6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

861:C4N20 RS09135
gene id: 861:C4N20_RS09135
uniprot id: A0A2P1S485
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

861:C4N20 RS09405
gene id: 861:C4N20_RS09405
uniprot id: A0A2P1S4E7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861:C4N20 RS04760
gene id: 861:C4N20_RS04760
uniprot id: A0A2P1S1W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

861:C4N20 RS13575
gene id: 861:C4N20_RS13575
uniprot id: A0A2P1S6M9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

861:C4N20 RS07220
gene id: 861:C4N20_RS07220
uniprot id: A0A2P1S385
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS11660
gene id: 861:C4N20_RS11660
uniprot id: A0A2P1S5M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

861:C4N20 RS05365
gene id: 861:C4N20_RS05365
uniprot id: A0A2P1S277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

861:C4N20 RS10095
gene id: 861:C4N20_RS10095
uniprot id: A0A2P1S594
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

861:C4N20 RS00405
gene id: 861:C4N20_RS00405
uniprot id: A0A2P1RZJ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861:C4N20 RS11605
gene id: 861:C4N20_RS11605
uniprot id: A0A2P1S5K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS15120
gene id: 861:C4N20_RS15120
uniprot id: A0A2P1S7F4
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

861:C4N20 RS03150
gene id: 861:C4N20_RS03150
uniprot id: A0A2P1S158
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

861:C4N20 RS08990
gene id: 861:C4N20_RS08990
uniprot id: A0A2P1S454
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

861:C4N20 RS04245
gene id: 861:C4N20_RS04245
uniprot id: A0A2P1S1R8
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS12510
gene id: 861:C4N20_RS12510
uniprot id: A0A2P1S636
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

861:C4N20 RS03175
gene id: 861:C4N20_RS03175
uniprot id: A0A2P1S1H8
names: Similarity
messages: Belongs to the peptidase S66 family.

861:C4N20 RS07990
gene id: 861:C4N20_RS07990
uniprot id: A0A2P1S3L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS01605
gene id: 861:C4N20_RS01605
uniprot id: A0A2P1S070
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

861:C4N20 RS11630
gene id: 861:C4N20_RS11630
uniprot id: A0A2P1S5J5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

861:C4N20 RS10810
gene id: 861:C4N20_RS10810
uniprot id: A0A2P1S575
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

861:C4N20 RS07210
gene id: 861:C4N20_RS07210
uniprot id: A0A2P1S368
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

861:C4N20 RS13125
gene id: 861:C4N20_RS13125
uniprot id: A0A2P1S6E4
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

861:C4N20 RS01810
gene id: 861:C4N20_RS01810
uniprot id: A0A2P1S0A9
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS10635
gene id: 861:C4N20_RS10635
uniprot id: A0A2P1S5I9
names: Subunit
messages: The proenzyme is a hexamer of identical pi chains; each pi chain monomer is cleaved to form a small (or beta) chain and a large (or alpha) chain by non-hydrolytic self-catalysis.

861:C4N20 RS09385
gene id: 861:C4N20_RS09385
uniprot id: A0A2P1S4U2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

861:C4N20 RS04540
gene id: 861:C4N20_RS04540
uniprot id: A0A2P1S274
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS07665
gene id: 861:C4N20_RS07665
uniprot id: A0A2P1S3G2
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

861:C4N20 RS11510
gene id: 861:C4N20_RS11510
uniprot id: A0A2P1S604
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

861:C4N20 RS13075
gene id: 861:C4N20_RS13075
uniprot id: A0A2P1S6D4
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS11580
gene id: 861:C4N20_RS11580
uniprot id: A0A2P1S8E8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

861:C4N20 RS14010
gene id: 861:C4N20_RS14010
uniprot id: A0A2P1S6X9
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS15965
gene id: 861:C4N20_RS15965
uniprot id: A0A2P1S7X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

861:C4N20 RS03165
gene id: 861:C4N20_RS03165
uniprot id: A0A2P1S134
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

861:C4N20 RS14100
gene id: 861:C4N20_RS14100
uniprot id: A0A2P1S6W3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

861:C4N20 RS13440
gene id: 861:C4N20_RS13440
uniprot id: A0A2P1S6M3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

861:C4N20 RS05470
gene id: 861:C4N20_RS05470
uniprot id: A0A2P1S288
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

861:C4N20 RS03520
gene id: 861:C4N20_RS03520
uniprot id: A0A2P1S1C1
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

861:C4N20 RS12555
gene id: 861:C4N20_RS12555
uniprot id: A0A2P1S6B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

861:C4N20 RS07570
gene id: 861:C4N20_RS07570
uniprot id: A0A2P1S3C8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

861:C4N20 RS01690
gene id: 861:C4N20_RS01690
uniprot id: A0A2P1S092
names: Similarity
messages: Belongs to the YggT family.

861:C4N20 RS06435
gene id: 861:C4N20_RS06435
uniprot id: A0A2P1S2U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

861:C4N20 RS06475
gene id: 861:C4N20_RS06475
uniprot id: A0A2P1S3B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

861:C4N20 RS00820
gene id: 861:C4N20_RS00820
uniprot id: A0A2P1RZW5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS06855
gene id: 861:C4N20_RS06855
uniprot id: A0A2P1S2Z6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS13120
gene id: 861:C4N20_RS13120
uniprot id: A0A2P1S6C6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

861:C4N20 RS03035
gene id: 861:C4N20_RS03035
uniprot id: A0A2P1S1I6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

861:C4N20 RS08320
gene id: 861:C4N20_RS08320
uniprot id: A0A2P1S446
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS00715
gene id: 861:C4N20_RS00715
uniprot id: A0A2P1S057
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

861:C4N20 RS04855
gene id: 861:C4N20_RS04855
uniprot id: A0A2P1S241
names: Similarity
messages: Belongs to the GSP E family.

861:C4N20 RS13445
gene id: 861:C4N20_RS13445
uniprot id: A0A2P1S6J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

861:C4N20 RS03235
gene id: 861:C4N20_RS03235
uniprot id: A0A2P1S160
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS06205
gene id: 861:C4N20_RS06205
uniprot id: A0A2P1S2R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

861:C4N20 RS08795
gene id: 861:C4N20_RS08795
uniprot id: A0A2P1S428
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS08740
gene id: 861:C4N20_RS08740
uniprot id: A0A2P1S404
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

861:C4N20 RS09420
gene id: 861:C4N20_RS09420
uniprot id: A0A2P1S4F4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

861:C4N20 RS02640
gene id: 861:C4N20_RS02640
uniprot id: A0A2P1S0S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

861:C4N20 RS13865
gene id: 861:C4N20_RS13865
uniprot id: A0A2P1S6S2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

861:C4N20 RS06165
gene id: 861:C4N20_RS06165
uniprot id: A0A2P1S2L0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

861:C4N20 RS15095
gene id: 861:C4N20_RS15095
uniprot id: A0A2P1S830
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

861:C4N20 RS08730
gene id: 861:C4N20_RS08730
uniprot id: A0A2P1S3Z7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

861:C4N20 RS00480
gene id: 861:C4N20_RS00480
uniprot id: A0A2P1RZP9
names: Caution
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

861:C4N20 RS13940
gene id: 861:C4N20_RS13940
uniprot id: A0A2P1S7G4
names: Similarity
messages: Belongs to the ComB family.

861:C4N20 RS09300
gene id: 861:C4N20_RS09300
uniprot id: A0A2P1S4D3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

861:C4N20 RS09720
gene id: 861:C4N20_RS09720
uniprot id: A0A2P1S4W3
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

861:C4N20 RS01015
gene id: 861:C4N20_RS01015
uniprot id: A0A2P1RZW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS11200
gene id: 861:C4N20_RS11200
uniprot id: A0A2P1S5D8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

861:C4N20 RS02225
gene id: 861:C4N20_RS02225
uniprot id: A0A2P1S0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS14355
gene id: 861:C4N20_RS14355
uniprot id: A0A2P1S733
names: Similarity
messages: Belongs to the asparaginase 1 family.

861:C4N20 RS03970
gene id: 861:C4N20_RS03970
uniprot id: A0A2P1S225
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

861:C4N20 RS08235
gene id: 861:C4N20_RS08235
uniprot id: A0A2P1S462
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

861:C4N20 RS04680
gene id: 861:C4N20_RS04680
uniprot id: A0A2P1S1W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

861:C4N20 RS00545
gene id: 861:C4N20_RS00545
uniprot id: A0A2P1RZM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS08390
gene id: 861:C4N20_RS08390
uniprot id: A0A2P1S496
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS05780
gene id: 861:C4N20_RS05780
uniprot id: A0A2P1S2F3
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

861:C4N20 RS12650
gene id: 861:C4N20_RS12650
uniprot id: A0A2P1S653
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

861:C4N20 RS07970
gene id: 861:C4N20_RS07970
uniprot id: A0A2P1S3K7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS07695
gene id: 861:C4N20_RS07695
uniprot id: A0A2P1S3G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

861:C4N20 RS06210
gene id: 861:C4N20_RS06210
uniprot id: A0A2P1S2Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

861:C4N20 RS03375
gene id: 861:C4N20_RS03375
uniprot id: A0A2P1S165
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS06570
gene id: 861:C4N20_RS06570
uniprot id: A0A2P1S2W3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

861:C4N20 RS15425
gene id: 861:C4N20_RS15425
uniprot id: A0A2P1S7N6
names: Similarity
messages: Belongs to the class-I fumarase family.

861:C4N20 RS01725
gene id: 861:C4N20_RS01725
uniprot id: A0A2P1S0U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS09440
gene id: 861:C4N20_RS09440
uniprot id: A0A2P1S4D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

861:C4N20 RS11340
gene id: 861:C4N20_RS11340
uniprot id: A0A2P1S5G5
names: Similarity
messages: Belongs to the FBPase class 2 family.

861:C4N20 RS07050
gene id: 861:C4N20_RS07050
uniprot id: A0A2P1S339
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

861:C4N20 RS05725
gene id: 861:C4N20_RS05725
uniprot id: A0A2P1S2E2
names: Similarity
messages: Belongs to the RutC family.

861:C4N20 RS10140
gene id: 861:C4N20_RS10140
uniprot id: A0A2P1S4S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

861:C4N20 RS10835
gene id: 861:C4N20_RS10835
uniprot id: A0A2P1S551
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

861:C4N20 RS07375
gene id: 861:C4N20_RS07375
uniprot id: A0A2P1S3B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

861:C4N20 RS02155
gene id: 861:C4N20_RS02155
uniprot id: A0A2P1S0H7
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS05325
gene id: 861:C4N20_RS05325
uniprot id: A0A2P1S257
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

861:C4N20 RS00415
gene id: 861:C4N20_RS00415
uniprot id: A0A2P1S040
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS11745
gene id: 861:C4N20_RS11745
uniprot id: A0A2P1S646
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS00960
gene id: 861:C4N20_RS00960
uniprot id: A0A2P1RZU8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS08250
gene id: 861:C4N20_RS08250
uniprot id: A0A2P1S3S3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861:C4N20 RS13570
gene id: 861:C4N20_RS13570
uniprot id: A0A2P1S782
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS07885
gene id: 861:C4N20_RS07885
uniprot id: A0A2P1S3K1
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS13220
gene id: 861:C4N20_RS13220
uniprot id: A0A2P1S6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

861:C4N20 RS11775
gene id: 861:C4N20_RS11775
uniprot id: A0A2P1S5Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

861:C4N20 RS02965
gene id: 861:C4N20_RS02965
uniprot id: A0A2P1S1C9
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS15390
gene id: 861:C4N20_RS15390
uniprot id: A0A2P1S7N3
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

861:C4N20 RS09875
gene id: 861:C4N20_RS09875
uniprot id: A0A2P1S4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

861:C4N20 RS15305
gene id: 861:C4N20_RS15305
uniprot id: A0A2P1S7L1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

861:C4N20 RS04085
gene id: 861:C4N20_RS04085
uniprot id: A0A2P1S1N3
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS04180
gene id: 861:C4N20_RS04180
uniprot id: A0A2P1S1N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

861:C4N20 RS07745
gene id: 861:C4N20_RS07745
uniprot id: A0A2P1S8C5
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

861:C4N20 RS14140
gene id: 861:C4N20_RS14140
uniprot id: A0A2P1S769
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

861:C4N20 RS10090
gene id: 861:C4N20_RS10090
uniprot id: A0A2P1S4S2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS07905
gene id: 861:C4N20_RS07905
uniprot id: A0A2P1S3J9
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

861:C4N20 RS02430
gene id: 861:C4N20_RS02430
uniprot id: A0A2P1S0N0
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS14650
gene id: 861:C4N20_RS14650
uniprot id: A0A2P1S765
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS02900
gene id: 861:C4N20_RS02900
uniprot id: A0A2P1S0X3
names: Similarity
messages: Belongs to the thioredoxin family.

861:C4N20 RS13620
gene id: 861:C4N20_RS13620
uniprot id: A0A2P1S6M5
names: Similarity
messages: Belongs to the UPF0178 family.

861:C4N20 RS04705
gene id: 861:C4N20_RS04705
uniprot id: A0A2P1S1W5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

861:C4N20 RS07025
gene id: 861:C4N20_RS07025
uniprot id: A0A2P1S3F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

861:C4N20 RS12625
gene id: 861:C4N20_RS12625
uniprot id: A0A2P1S6N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

861:C4N20 RS06170
gene id: 861:C4N20_RS06170
uniprot id: A0A2P1S2S9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

861:C4N20 RS00350
gene id: 861:C4N20_RS00350
uniprot id: A0A2P1RZL6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

861:C4N20 RS05695
gene id: 861:C4N20_RS05695
uniprot id: A0A2P1S2G8
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

861:C4N20 RS06755
gene id: 861:C4N20_RS06755
uniprot id: A0A2P1S2X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

861:C4N20 RS08435
gene id: 861:C4N20_RS08435
uniprot id: A0A2P1S3U4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

861:C4N20 RS05280
gene id: 861:C4N20_RS05280
uniprot id: A0A2P1S2C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

861:C4N20 RS16290
gene id: 861:C4N20_RS16290
uniprot id: A0A2P1S821
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

861:C4N20 RS03740
gene id: 861:C4N20_RS03740
uniprot id: A0A2P1S1H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

861:C4N20 RS16370
gene id: 861:C4N20_RS16370
uniprot id: A0A2P1S883
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

861:C4N20 RS00390
gene id: 861:C4N20_RS00390
uniprot id: A0A2P1RZK4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861:C4N20 RS02190
gene id: 861:C4N20_RS02190
uniprot id: A0A2P1S0Y4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

861:C4N20 RS13470
gene id: 861:C4N20_RS13470
uniprot id: A0A2P1S6M2
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS04535
gene id: 861:C4N20_RS04535
uniprot id: A0A2P1S1X2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS14585
gene id: 861:C4N20_RS14585
uniprot id: A0A2P1S766
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

861:C4N20 RS01385
gene id: 861:C4N20_RS01385
uniprot id: A0A2P1S033
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

861:C4N20 RS10315
gene id: 861:C4N20_RS10315
uniprot id: A0A2P1S5D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

861:C4N20 RS03900
gene id: 861:C4N20_RS03900
uniprot id: A0A2P1S1X1
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

861:C4N20 RS00465
gene id: 861:C4N20_RS00465
uniprot id: A0A2P1RZM5
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

861:C4N20 RS03450
gene id: 861:C4N20_RS03450
uniprot id: A0A2P1S191
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

861:C4N20 RS00515
gene id: 861:C4N20_RS00515
uniprot id: A0A2P1RZQ5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

861:C4N20 RS07275
gene id: 861:C4N20_RS07275
uniprot id: A0A2P1S394
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

861:C4N20 RS13325
gene id: 861:C4N20_RS13325
uniprot id: A0A2P1S6H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

861:C4N20 RS09520
gene id: 861:C4N20_RS09520
uniprot id: A0A2P1S4R4
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

861:C4N20 RS16365
gene id: 861:C4N20_RS16365
uniprot id: A0A2P1S856
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

861:C4N20 RS04870
gene id: 861:C4N20_RS04870
uniprot id: A0A2P1S231
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS01310
gene id: 861:C4N20_RS01310
uniprot id: A0A2P1S0L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

861:C4N20 RS05330
gene id: 861:C4N20_RS05330
uniprot id: A0A2P1S2D1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

861:C4N20 RS02820
gene id: 861:C4N20_RS02820
uniprot id: A0A2P1S0V1
names: Similarity
messages: Belongs to the peptidase M16 family.

861:C4N20 RS11140
gene id: 861:C4N20_RS11140
uniprot id: A0A2P1S8B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

861:C4N20 RS09465
gene id: 861:C4N20_RS09465
uniprot id: A0A2P1S4Q4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

861:C4N20 RS03260
gene id: 861:C4N20_RS03260
uniprot id: A0A2P1S152
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

861:C4N20 RS03460
gene id: 861:C4N20_RS03460
uniprot id: A0A2P1S189
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

861:C4N20 RS03700
gene id: 861:C4N20_RS03700
uniprot id: A0A2P1S1D2
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS12665
gene id: 861:C4N20_RS12665
uniprot id: A0A2P1S645
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

861:C4N20 RS14420
gene id: 861:C4N20_RS14420
uniprot id: A0A2P1S7Q5
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS05015
gene id: 861:C4N20_RS05015
uniprot id: A0A2P1S264
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

861:C4N20 RS11015
gene id: 861:C4N20_RS11015
uniprot id: A0A2P1S5A6
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

861:C4N20 RS08525
gene id: 861:C4N20_RS08525
uniprot id: A0A2P1S3Z1
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS15105
gene id: 861:C4N20_RS15105
uniprot id: A0A2P1S7E9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

861:C4N20 RS15925
gene id: 861:C4N20_RS15925
uniprot id: A0A2P1S7X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

861:C4N20 RS01065
gene id: 861:C4N20_RS01065
uniprot id: A0A2P1RZX1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

861:C4N20 RS06860
gene id: 861:C4N20_RS06860
uniprot id: A0A2P1S2Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

861:C4N20 RS00095
gene id: 861:C4N20_RS00095
uniprot id: A0A2P1RZF4
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS06445
gene id: 861:C4N20_RS06445
uniprot id: A0A2P1S2R2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS13095
gene id: 861:C4N20_RS13095
uniprot id: A0A2P1S6D7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861:C4N20 RS05685
gene id: 861:C4N20_RS05685
uniprot id: A0A2P1S2V3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

861:C4N20 RS11595
gene id: 861:C4N20_RS11595
uniprot id: A0A2P1S5J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

861:C4N20 RS08180
gene id: 861:C4N20_RS08180
uniprot id: A0A2P1S443
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS14110
gene id: 861:C4N20_RS14110
uniprot id: A0A2P1S6W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

861:C4N20 RS15340
gene id: 861:C4N20_RS15340
uniprot id: A0A2P1S7M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS08685
gene id: 861:C4N20_RS08685
uniprot id: A0A2P1S3Z6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

861:C4N20 RS13105
gene id: 861:C4N20_RS13105
uniprot id: A0A2P1S6D1
names: Similarity
messages: Belongs to the pyruvate kinase family.

861:C4N20 RS06430
gene id: 861:C4N20_RS06430
uniprot id: A0A2P1S2U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

861:C4N20 RS09470
gene id: 861:C4N20_RS09470
uniprot id: A0A2P1S4G3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

861:C4N20 RS05480
gene id: 861:C4N20_RS05480
uniprot id: A0A2P1S2A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

861:C4N20 RS05270
gene id: 861:C4N20_RS05270
uniprot id: A0A2P1S261
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

861:C4N20 RS06360
gene id: 861:C4N20_RS06360
uniprot id: A0A2P1S2T9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS14145
gene id: 861:C4N20_RS14145
uniprot id: A0A2P1S6Z2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

861:C4N20 RS00710
gene id: 861:C4N20_RS00710
uniprot id: A0A2P1RZR3
names: Similarity
messages: Belongs to the Fur family.

861:C4N20 RS16355
gene id: 861:C4N20_RS16355
uniprot id: A0A2P1S858
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

861:C4N20 RS02330
gene id: 861:C4N20_RS02330
uniprot id: A0A2P1S0K9
names: Similarity
messages: Belongs to the sigma-54 factor family.

861:C4N20 RS02785
gene id: 861:C4N20_RS02785
uniprot id: A0A2P1S0Z5
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS01705
gene id: 861:C4N20_RS01705
uniprot id: A0A2P1S0P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

861:C4N20 RS05450
gene id: 861:C4N20_RS05450
uniprot id: A0A2P1S2A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

861:C4N20 RS07475
gene id: 861:C4N20_RS07475
uniprot id: A0A2P1S3P2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

861:C4N20 RS05745
gene id: 861:C4N20_RS05745
uniprot id: A0A2P1S2I0
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS09860
gene id: 861:C4N20_RS09860
uniprot id: A0A2P1S4M4
names: Similarity
messages: Belongs to the thioredoxin family.

861:C4N20 RS00650
gene id: 861:C4N20_RS00650
uniprot id: A0A2P1RZN6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

861:C4N20 RS04025
gene id: 861:C4N20_RS04025
uniprot id: A0A2P1S1L3
names: Similarity
messages: Belongs to the peptidase S58 family.

861:C4N20 RS13300
gene id: 861:C4N20_RS13300
uniprot id: A0A2P1S6I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

861:C4N20 RS00015
gene id: 861:C4N20_RS00015
uniprot id: A0A2P1RZC2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

861:C4N20 RS05190
gene id: 861:C4N20_RS05190
uniprot id: A0A2P1S248
names: Similarity
messages: Belongs to the UxaA family.

861:C4N20 RS12045
gene id: 861:C4N20_RS12045
uniprot id: A0A2P1S5S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS10240
gene id: 861:C4N20_RS10240
uniprot id: A0A2P1S4V1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861:C4N20 RS08275
gene id: 861:C4N20_RS08275
uniprot id: A0A2P1S3S0
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS10105
gene id: 861:C4N20_RS10105
uniprot id: A0A2P1S4T6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

861:C4N20 RS03125
gene id: 861:C4N20_RS03125
uniprot id: A0A2P1S877
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS06680
gene id: 861:C4N20_RS06680
uniprot id: A0A2P1S2Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

861:C4N20 RS15115
gene id: 861:C4N20_RS15115
uniprot id: A0A2P1S7I9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

861:C4N20 RS16375
gene id: 861:C4N20_RS16375
uniprot id: A0A2P1S847
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

861:C4N20 RS00245
gene id: 861:C4N20_RS00245
uniprot id: A0A2P1RZG1
names: Similarity
messages: Belongs to the RuvC family.

861:C4N20 RS07125
gene id: 861:C4N20_RS07125
uniprot id: A0A2P1S3A0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

861:C4N20 RS03110
gene id: 861:C4N20_RS03110
uniprot id: A0A2P1S113
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS07240
gene id: 861:C4N20_RS07240
uniprot id: A0A2P1S3K3
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

861:C4N20 RS09900
gene id: 861:C4N20_RS09900
uniprot id: A0A2P1S4N2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

861:C4N20 RS00655
gene id: 861:C4N20_RS00655
uniprot id: A0A2P1RZP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

861:C4N20 RS09790
gene id: 861:C4N20_RS09790
uniprot id: A0A2P1S4L3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

861:C4N20 RS15590
gene id: 861:C4N20_RS15590
uniprot id: A0A2P1S7R6
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS08580
gene id: 861:C4N20_RS08580
uniprot id: A0A2P1S4A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

861:C4N20 RS08115
gene id: 861:C4N20_RS08115
uniprot id: A0A2P1S3M6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

861:C4N20 RS08585
gene id: 861:C4N20_RS08585
uniprot id: A0A2P1S3Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

861:C4N20 RS08545
gene id: 861:C4N20_RS08545
uniprot id: A0A2P1S3W6
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS00810
gene id: 861:C4N20_RS00810
uniprot id: A0A2P1RZS8
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS00385
gene id: 861:C4N20_RS00385
uniprot id: A0A2P1RZI9
names: Similarity
messages: Belongs to the peptidase M20A family.

861:C4N20 RS09915
gene id: 861:C4N20_RS09915
uniprot id: A0A2P1S4P1
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

861:C4N20 RS04360
gene id: 861:C4N20_RS04360
uniprot id: A0A2P1S1Q1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

861:C4N20 RS08745
gene id: 861:C4N20_RS08745
uniprot id: A0A2P1S418
names: Similarity
messages: Belongs to the fabD family.

861:C4N20 RS09450
gene id: 861:C4N20_RS09450
uniprot id: A0A2P1S4E5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS09455
gene id: 861:C4N20_RS09455
uniprot id: A0A2P1S4F5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

861:C4N20 RS14050
gene id: 861:C4N20_RS14050
uniprot id: A0A2P1S6V8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

861:C4N20 RS02480
gene id: 861:C4N20_RS02480
uniprot id: A0A2P1S0P0
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS02340
gene id: 861:C4N20_RS02340
uniprot id: A0A2P1S0M4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS06770
gene id: 861:C4N20_RS06770
uniprot id: A0A2P1S2Z9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

861:C4N20 RS08785
gene id: 861:C4N20_RS08785
uniprot id: A0A2P1S411
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

861:C4N20 RS14180
gene id: 861:C4N20_RS14180
uniprot id: A0A2P1S6Z6
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

861:C4N20 RS13410
gene id: 861:C4N20_RS13410
uniprot id: A0A2P1S6J4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS06810
gene id: 861:C4N20_RS06810
uniprot id: A0A2P1S2Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

861:C4N20 RS04260
gene id: 861:C4N20_RS04260
uniprot id: A0A2P1S1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

861:C4N20 RS07385
gene id: 861:C4N20_RS07385
uniprot id: A0A2P1S3A1
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS09500
gene id: 861:C4N20_RS09500
uniprot id: A0A2P1S4E6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

861:C4N20 RS09145
gene id: 861:C4N20_RS09145
uniprot id: A0A2P1S498
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

861:C4N20 RS01240
gene id: 861:C4N20_RS01240
uniprot id: A0A2P1S046
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

861:C4N20 RS16250
gene id: 861:C4N20_RS16250
uniprot id: A0A2P1S8P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

861:C4N20 RS08095
gene id: 861:C4N20_RS08095
uniprot id: A0A2P1S3N6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

861:C4N20 RS00440
gene id: 861:C4N20_RS00440
uniprot id: A0A2P1RZK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS06150
gene id: 861:C4N20_RS06150
uniprot id: A0A2P1S2P1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

861:C4N20 RS11930
gene id: 861:C4N20_RS11930
uniprot id: A0A2P1S5S4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS08425
gene id: 861:C4N20_RS08425
uniprot id: A0A2P1S3V5
names: Similarity
messages: Belongs to the PRORSD1 family.

861:C4N20 RS03445
gene id: 861:C4N20_RS03445
uniprot id: A0A2P1S8F5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

861:C4N20 RS03100
gene id: 861:C4N20_RS03100
uniprot id: A0A2P1S117
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS11355
gene id: 861:C4N20_RS11355
uniprot id: A0A2P1S5H8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

861:C4N20 RS13915
gene id: 861:C4N20_RS13915
uniprot id: A0A2P1S6T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

861:C4N20 RS07655
gene id: 861:C4N20_RS07655
uniprot id: A0A2P1S3F6
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

861:C4N20 RS00625
gene id: 861:C4N20_RS00625
uniprot id: A0A2P1RZN0
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

861:C4N20 RS03145
gene id: 861:C4N20_RS03145
uniprot id: A0A2P1S1L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

861:C4N20 RS08260
gene id: 861:C4N20_RS08260
uniprot id: A0A2P1S3V1
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS08775
gene id: 861:C4N20_RS08775
uniprot id: A0A2P1S4H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

861:C4N20 RS16285
gene id: 861:C4N20_RS16285
uniprot id: A0A2P1S849
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

861:C4N20 RS03965
gene id: 861:C4N20_RS03965
uniprot id: A0A2P1S1J1
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS14015
gene id: 861:C4N20_RS14015
uniprot id: A0A2P1S6X1
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS02750
gene id: 861:C4N20_RS02750
uniprot id: A0A2P1S0U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

861:C4N20 RS12030
gene id: 861:C4N20_RS12030
uniprot id: A0A2P1S633
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS01355
gene id: 861:C4N20_RS01355
uniprot id: A0A2P1S024
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

861:C4N20 RS12095
gene id: 861:C4N20_RS12095
uniprot id: A0A2P1S5T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

861:C4N20 RS01465
gene id: 861:C4N20_RS01465
uniprot id: A0A2P1S0P5
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

861:C4N20 RS02880
gene id: 861:C4N20_RS02880
uniprot id: A0A2P1S1F2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

861:C4N20 RS08345
gene id: 861:C4N20_RS08345
uniprot id: A0A2P1S3T4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861:C4N20 RS12740
gene id: 861:C4N20_RS12740
uniprot id: A0A2P1S668
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS01185
gene id: 861:C4N20_RS01185
uniprot id: A0A2P1S036
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

861:C4N20 RS04155
gene id: 861:C4N20_RS04155
uniprot id: A0A2P1S210
names: Similarity
messages: Belongs to the aspartokinase family.

861:C4N20 RS06450
gene id: 861:C4N20_RS06450
uniprot id: A0A2P1S2Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

861:C4N20 RS00775
gene id: 861:C4N20_RS00775
uniprot id: A0A2P1RZR5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

861:C4N20 RS03585
gene id: 861:C4N20_RS03585
uniprot id: A0A2P1S1A7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

861:C4N20 RS01755
gene id: 861:C4N20_RS01755
uniprot id: A0A2P1S0Q9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

861:C4N20 RS08015
gene id: 861:C4N20_RS08015
uniprot id: A0A2P1S3K2
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

861:C4N20 RS05145
gene id: 861:C4N20_RS05145
uniprot id: A0A2P1S216
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

861:C4N20 RS07770
gene id: 861:C4N20_RS07770
uniprot id: A0A2P1S3X2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

861:C4N20 RS16185
gene id: 861:C4N20_RS16185
uniprot id: A0A2P1S803
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS06455
gene id: 861:C4N20_RS06455
uniprot id: A0A2P1S352
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

861:C4N20 RS14020
gene id: 861:C4N20_RS14020
uniprot id: A0A2P1S6V3
names: Similarity
messages: Belongs to the leucine-binding protein family.

861:C4N20 RS04615
gene id: 861:C4N20_RS04615
uniprot id: A0A2P1S1V6
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS07020
gene id: 861:C4N20_RS07020
uniprot id: A0A2P1S380
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

861:C4N20 RS08505
gene id: 861:C4N20_RS08505
uniprot id: A0A2P1S3W1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

861:C4N20 RS15360
gene id: 861:C4N20_RS15360
uniprot id: A0A2P1S7K0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

861:C4N20 RS03720
gene id: 861:C4N20_RS03720
uniprot id: A0A2P1S1F8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

861:C4N20 RS02520
gene id: 861:C4N20_RS02520
uniprot id: A0A2P1S0U3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

861:C4N20 RS08645
gene id: 861:C4N20_RS08645
uniprot id: A0A2P1S4B0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

861:C4N20 RS11705
gene id: 861:C4N20_RS11705
uniprot id: A0A2P1S5N1
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS02800
gene id: 861:C4N20_RS02800
uniprot id: A0A2P1S0V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

861:C4N20 RS11970
gene id: 861:C4N20_RS11970
uniprot id: A0A2P1S5Q9
names: Similarity
messages: Belongs to the SfsA family.

861:C4N20 RS02270
gene id: 861:C4N20_RS02270
uniprot id: A0A2P1S0K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

861:C4N20 RS04200
gene id: 861:C4N20_RS04200
uniprot id: A0A2P1S1R0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

861:C4N20 RS16210
gene id: 861:C4N20_RS16210
uniprot id: A0A2P1S815
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

861:C4N20 RS04885
gene id: 861:C4N20_RS04885
uniprot id: A0A2P1S1X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS09485
gene id: 861:C4N20_RS09485
uniprot id: A0A2P1S4W2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

861:C4N20 RS01685
gene id: 861:C4N20_RS01685
uniprot id: A0A2P1S094
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

861:C4N20 RS03370
gene id: 861:C4N20_RS03370
uniprot id: A0A2P1S185
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

861:C4N20 RS06640
gene id: 861:C4N20_RS06640
uniprot id: A0A2P1S315
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS04745
gene id: 861:C4N20_RS04745
uniprot id: A0A2P1S1Y7
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

861:C4N20 RS10320
gene id: 861:C4N20_RS10320
uniprot id: A0A2P1S4V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

861:C4N20 RS10030
gene id: 861:C4N20_RS10030
uniprot id: A0A2P1S4T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS10185
gene id: 861:C4N20_RS10185
uniprot id: A0A2P1S4W4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

861:C4N20 RS09370
gene id: 861:C4N20_RS09370
uniprot id: A0A2P1S4E8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

861:C4N20 RS04510
gene id: 861:C4N20_RS04510
uniprot id: A0A2P1S2D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

861:C4N20 RS12075
gene id: 861:C4N20_RS12075
uniprot id: A0A2P1S5T8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

861:C4N20 RS03290
gene id: 861:C4N20_RS03290
uniprot id: A0A2P1S139
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS09345
gene id: 861:C4N20_RS09345
uniprot id: A0A2P1S4C0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

861:C4N20 RS01635
gene id: 861:C4N20_RS01635
uniprot id: A0A2P1S083
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

861:C4N20 RS02805
gene id: 861:C4N20_RS02805
uniprot id: A0A2P1S0W8
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

861:C4N20 RS10335
gene id: 861:C4N20_RS10335
uniprot id: A0A2P1S4X9
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

861:C4N20 RS03115
gene id: 861:C4N20_RS03115
uniprot id: A0A2P1S141
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

861:C4N20 RS11150
gene id: 861:C4N20_RS11150
uniprot id: A0A2P1S5B9
names: Similarity
messages: Belongs to the DprA/Smf family.

861:C4N20 RS13190
gene id: 861:C4N20_RS13190
uniprot id: A0A2P1S6E5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS10990
gene id: 861:C4N20_RS10990
uniprot id: A0A2P1S5B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

861:C4N20 RS10875
gene id: 861:C4N20_RS10875
uniprot id: A0A2P1S592
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

861:C4N20 RS15215
gene id: 861:C4N20_RS15215
uniprot id: A0A2P1S7K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

861:C4N20 RS04230
gene id: 861:C4N20_RS04230
uniprot id: A0A2P1S1P1
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS06610
gene id: 861:C4N20_RS06610
uniprot id: A0A2P1S2X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

861:C4N20 RS11650
gene id: 861:C4N20_RS11650
uniprot id: A0A2P1S5L1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS06185
gene id: 861:C4N20_RS06185
uniprot id: A0A2P1S2L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

861:C4N20 RS02755
gene id: 861:C4N20_RS02755
uniprot id: A0A2P1S0V8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

861:C4N20 RS11130
gene id: 861:C4N20_RS11130
uniprot id: A0A2P1S5B3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

861:C4N20 RS05690
gene id: 861:C4N20_RS05690
uniprot id: A0A2P1S2D8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

861:C4N20 RS03005
gene id: 861:C4N20_RS03005
uniprot id: A0A2P1S0Z2
names: Similarity
messages: Belongs to the HepT RNase toxin family.

861:C4N20 RS14940
gene id: 861:C4N20_RS14940
uniprot id: A0A2P1S7F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

861:C4N20 RS00080
gene id: 861:C4N20_RS00080
uniprot id: A0A2P1RZU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

861:C4N20 RS14570
gene id: 861:C4N20_RS14570
uniprot id: A0A2P1S7U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

861:C4N20 RS01250
gene id: 861:C4N20_RS01250
uniprot id: A0A2P1S019
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

861:C4N20 RS05795
gene id: 861:C4N20_RS05795
uniprot id: A0A2P1S2J0
names: Similarity
messages: Belongs to the UPF0597 family.

861:C4N20 RS09100
gene id: 861:C4N20_RS09100
uniprot id: A0A2P1S499
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS00670
gene id: 861:C4N20_RS00670
uniprot id: A0A2P1RZT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

861:C4N20 RS09680
gene id: 861:C4N20_RS09680
uniprot id: A0A2P1S4J2
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS15065
gene id: 861:C4N20_RS15065
uniprot id: A0A2P1S8K0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

861:C4N20 RS00445
gene id: 861:C4N20_RS00445
uniprot id: A0A2P1RZL4
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS11940
gene id: 861:C4N20_RS11940
uniprot id: A0A2P1S5Q8
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

861:C4N20 RS09525
gene id: 861:C4N20_RS09525
uniprot id: A0A2P1S4H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

861:C4N20 RS02160
gene id: 861:C4N20_RS02160
uniprot id: A0A2P1S118
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS08750
gene id: 861:C4N20_RS08750
uniprot id: A0A2P1S441
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

861:C4N20 RS15395
gene id: 861:C4N20_RS15395
uniprot id: A0A2P1S7L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

861:C4N20 RS01735
gene id: 861:C4N20_RS01735
uniprot id: A0A2P1S0A4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

861:C4N20 RS02305
gene id: 861:C4N20_RS02305
uniprot id: A0A2P1S0L0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

861:C4N20 RS15405
gene id: 861:C4N20_RS15405
uniprot id: A0A2P1S7M2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS00400
gene id: 861:C4N20_RS00400
uniprot id: A0A2P1RZM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

861:C4N20 RS06155
gene id: 861:C4N20_RS06155
uniprot id: A0A2P1S2Q1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

861:C4N20 RS08575
gene id: 861:C4N20_RS08575
uniprot id: A0A2P1S402
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

861:C4N20 RS06245
gene id: 861:C4N20_RS06245
uniprot id: A0A2P1S374
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

861:C4N20 RS03170
gene id: 861:C4N20_RS03170
uniprot id: A0A2P1S155
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

861:C4N20 RS05860
gene id: 861:C4N20_RS05860
uniprot id: A0A2P1S2L3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

861:C4N20 RS03425
gene id: 861:C4N20_RS03425
uniprot id: A0A2P1S178
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

861:C4N20 RS09400
gene id: 861:C4N20_RS09400
uniprot id: A0A2P1S4D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

861:C4N20 RS07350
gene id: 861:C4N20_RS07350
uniprot id: A0A2P1S379
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

861:C4N20 RS01150
gene id: 861:C4N20_RS01150
uniprot id: A0A2P1S0I6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS04605
gene id: 861:C4N20_RS04605
uniprot id: A0A2P1S1V2
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS02470
gene id: 861:C4N20_RS02470
uniprot id: A0A2P1S0T1
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

861:C4N20 RS01565
gene id: 861:C4N20_RS01565
uniprot id: A0A2P1S0R6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

861:C4N20 RS12615
gene id: 861:C4N20_RS12615
uniprot id: A0A2P1S635
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS15970
gene id: 861:C4N20_RS15970
uniprot id: A0A2P1S857
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

861:C4N20 RS11405
gene id: 861:C4N20_RS11405
uniprot id: A0A2P1S5Y3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

861:C4N20 RS07290
gene id: 861:C4N20_RS07290
uniprot id: A0A2P1S3L3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

861:C4N20 RS04140
gene id: 861:C4N20_RS04140
uniprot id: A0A2P1S1L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

861:C4N20 RS13925
gene id: 861:C4N20_RS13925
uniprot id: A0A2P1S6V4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS05075
gene id: 861:C4N20_RS05075
uniprot id: A0A2P1S222
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

861:C4N20 RS01130
gene id: 861:C4N20_RS01130
uniprot id: A0A2P1S0D8
names: Subcellular Location Annotation
messages: Cytoplasm

861:C4N20 RS02740
gene id: 861:C4N20_RS02740
uniprot id: A0A2P1S0U6
names: Similarity
messages: Belongs to the UPF0265 family.

861:C4N20 RS12235
gene id: 861:C4N20_RS12235
uniprot id: A0A2P1S661
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

861:C4N20 RS10780
gene id: 861:C4N20_RS10780
uniprot id: A0A2P1S545
names: Similarity
messages: Belongs to the UPF0237 family.

861:C4N20 RS02250
gene id: 861:C4N20_RS02250
uniprot id: A0A2P1S0J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS08470
gene id: 861:C4N20_RS08470
uniprot id: A0A2P1S476
names: Cofactor
messages: Binds 1 zinc ion per subunit.

861:C4N20 RS01215
gene id: 861:C4N20_RS01215
uniprot id: A0A2P1S000
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

861:C4N20 RS06480
gene id: 861:C4N20_RS06480
uniprot id: A0A2P1S2V6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

861:C4N20 RS03630
gene id: 861:C4N20_RS03630
uniprot id: A0A2P1S1B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

861:C4N20 RS02575
gene id: 861:C4N20_RS02575
uniprot id: A0A2P1S0R5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

861:C4N20 RS06845
gene id: 861:C4N20_RS06845
uniprot id: A0A2P1S355
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

861:C4N20 RS09125
gene id: 861:C4N20_RS09125
uniprot id: A0A2P1S4N4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS03985
gene id: 861:C4N20_RS03985
uniprot id: A0A2P1S1I1
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

861:C4N20 RS12525
gene id: 861:C4N20_RS12525
uniprot id: A0A2P1S6L3
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS02295
gene id: 861:C4N20_RS02295
uniprot id: A0A2P1S0P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

861:C4N20 RS07735
gene id: 861:C4N20_RS07735
uniprot id: A0A2P1S3H2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS05520
gene id: 861:C4N20_RS05520
uniprot id: A0A2P1S2P7
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

861:C4N20 RS11160
gene id: 861:C4N20_RS11160
uniprot id: A0A2P1S5T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

861:C4N20 RS08070
gene id: 861:C4N20_RS08070
uniprot id: A0A2P1S3M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS09005
gene id: 861:C4N20_RS09005
uniprot id: A0A2P1S4H8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

861:C4N20 RS08055
gene id: 861:C4N20_RS08055
uniprot id: A0A2P1S3Z3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

861:C4N20 RS04415
gene id: 861:C4N20_RS04415
uniprot id: A0A2P1S1V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

861:C4N20 RS05525
gene id: 861:C4N20_RS05525
uniprot id: A0A2P1S294
names: Similarity
messages: Belongs to the Fur family.

861:C4N20 RS05930
gene id: 861:C4N20_RS05930
uniprot id: A0A2P1S2I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS08850
gene id: 861:C4N20_RS08850
uniprot id: A0A2P1S452
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS01140
gene id: 861:C4N20_RS01140
uniprot id: A0A2P1RZY3
names: Subcellular Location Annotation
messages: Cytoplasm

861:C4N20 RS10005
gene id: 861:C4N20_RS10005
uniprot id: A0A2P1S4R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS03960
gene id: 861:C4N20_RS03960
uniprot id: A0A2P1S1H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

861:C4N20 RS09270
gene id: 861:C4N20_RS09270
uniprot id: A0A2P1S4A3
names: Similarity
messages: Belongs to the asp23 family.

861:C4N20 RS06745
gene id: 861:C4N20_RS06745
uniprot id: A0A2P1S399
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

861:C4N20 RS02890
gene id: 861:C4N20_RS02890
uniprot id: A0A2P1S0X6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

861:C4N20 RS02450
gene id: 861:C4N20_RS02450
uniprot id: A0A2P1S0S6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

861:C4N20 RS07415
gene id: 861:C4N20_RS07415
uniprot id: A0A2P1S3R5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

861:C4N20 RS12065
gene id: 861:C4N20_RS12065
uniprot id: A0A2P1S5V2
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

861:C4N20 RS06525
gene id: 861:C4N20_RS06525
uniprot id: A0A2P1S3C3
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

861:C4N20 RS14425
gene id: 861:C4N20_RS14425
uniprot id: A0A2P1S736
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

861:C4N20 RS10850
gene id: 861:C4N20_RS10850
uniprot id: A0A2P1S568
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS01715
gene id: 861:C4N20_RS01715
uniprot id: A0A2P1S089
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS09325
gene id: 861:C4N20_RS09325
uniprot id: A0A2P1S4B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

861:C4N20 RS02850
gene id: 861:C4N20_RS02850
uniprot id: A0A2P1S0W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

861:C4N20 RS16320
gene id: 861:C4N20_RS16320
uniprot id: A0A2P1S874
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861:C4N20 RS06505
gene id: 861:C4N20_RS06505
uniprot id: A0A2P1S361
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

861:C4N20 RS16345
gene id: 861:C4N20_RS16345
uniprot id: A0A2P1S841
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS10325
gene id: 861:C4N20_RS10325
uniprot id: A0A2P1S4X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

861:C4N20 RS08040
gene id: 861:C4N20_RS08040
uniprot id: A0A2P1S3N4
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS10495
gene id: 861:C4N20_RS10495
uniprot id: A0A2P1S503
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

861:C4N20 RS05840
gene id: 861:C4N20_RS05840
uniprot id: A0A2P1S2H8
names: Similarity
messages: Belongs to the KdgT transporter family.

861:C4N20 RS05735
gene id: 861:C4N20_RS05735
uniprot id: A0A2P1S2V9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861:C4N20 RS08155
gene id: 861:C4N20_RS08155
uniprot id: A0A2P1S410
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

861:C4N20 RS07835
gene id: 861:C4N20_RS07835
uniprot id: A0A2P1S3I6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

861:C4N20 RS08465
gene id: 861:C4N20_RS08465
uniprot id: A0A2P1S3Y2
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

861:C4N20 RS05175
gene id: 861:C4N20_RS05175
uniprot id: A0A2P1S235
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

861:C4N20 RS14095
gene id: 861:C4N20_RS14095
uniprot id: A0A2P1S6V5
names: Similarity
messages: Belongs to the aspartokinase family.

861:C4N20 RS00660
gene id: 861:C4N20_RS00660
uniprot id: A0A2P1RZQ1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

861:C4N20 RS14820
gene id: 861:C4N20_RS14820
uniprot id: A0A2P1S798
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

861:C4N20 RS15585
gene id: 861:C4N20_RS15585
uniprot id: A0A2P1S7Q0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

861:C4N20 RS13655
gene id: 861:C4N20_RS13655
uniprot id: A0A2P1S6N6
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

861:C4N20 RS07670
gene id: 861:C4N20_RS07670
uniprot id: A0A2P1S3F8
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS11455
gene id: 861:C4N20_RS11455
uniprot id: A0A2P1S5F6
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS07305
gene id: 861:C4N20_RS07305
uniprot id: A0A2P1S395
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

861:C4N20 RS00675
gene id: 861:C4N20_RS00675
uniprot id: A0A2P1RZN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

861:C4N20 RS03530
gene id: 861:C4N20_RS03530
uniprot id: A0A2P1S193
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

861:C4N20 RS11670
gene id: 861:C4N20_RS11670
uniprot id: A0A2P1S5W4
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

861:C4N20 RS13495
gene id: 861:C4N20_RS13495
uniprot id: A0A2P1S6K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

861:C4N20 RS14830
gene id: 861:C4N20_RS14830
uniprot id: A0A2P1S7Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

861:C4N20 RS07555
gene id: 861:C4N20_RS07555
uniprot id: A0A2P1S3D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

861:C4N20 RS15730
gene id: 861:C4N20_RS15730
uniprot id: A0A2P1S7T5
names: Similarity
messages: Belongs to the peptidase S14 family.

861:C4N20 RS06905
gene id: 861:C4N20_RS06905
uniprot id: A0A2P1S304
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

861:C4N20 RS04225
gene id: 861:C4N20_RS04225
uniprot id: A0A2P1S1M3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

861:C4N20 RS00010
gene id: 861:C4N20_RS00010
uniprot id: A0A2P1RZC1
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

861:C4N20 RS06735
gene id: 861:C4N20_RS06735
uniprot id: A0A2P1S2X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

861:C4N20 RS05870
gene id: 861:C4N20_RS05870
uniprot id: A0A2P1S2G1
names: Subcellular Location Annotation
messages: Membrane

861:C4N20 RS03135
gene id: 861:C4N20_RS03135
uniprot id: A0A2P1S119
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

861:C4N20 RS06700
gene id: 861:C4N20_RS06700
uniprot id: A0A2P1S2W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

861:C4N20 RS15310
gene id: 861:C4N20_RS15310
uniprot id: A0A2P1S7I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

861:C4N20 RS00840
gene id: 861:C4N20_RS00840
uniprot id: A0A2P1RZX3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

861:C4N20 RS03835
gene id: 861:C4N20_RS03835
uniprot id: A0A2P1S1F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

861:C4N20 RS07195
gene id: 861:C4N20_RS07195
uniprot id: A0A2P1S350
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

861:C4N20 RS15075
gene id: 861:C4N20_RS15075
uniprot id: A0A2P1S7Q2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

861:C4N20 RS08715
gene id: 861:C4N20_RS08715
uniprot id: A0A2P1S401
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.