8469:CHST4
gene id: 8469:CHST4
uniprot id: M7BZ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8469:MRPS30
gene id: 8469:MRPS30
uniprot id: M7BX37
names: Subcellular Location Annotation
messages: Mitochondrion

8469:EIF4EBP2
gene id: 8469:EIF4EBP2
uniprot id: M7CI19
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

8469:TENT5C
gene id: 8469:TENT5C
uniprot id: M7ATZ5
names: Similarity
messages: Belongs to the TENT family.

8469:LOC102947191
gene id: 8469:LOC102947191
uniprot id: M7AKC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:EGR1
gene id: 8469:EGR1
uniprot id: M7B1K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

8469:BCL2L1
gene id: 8469:BCL2L1
uniprot id: M7B5M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane
messages: Mitochondrion matrix
messages: Nucleus membrane
messages: centrosome
messages: cytosol
messages: synaptic vesicle membrane

8469:MIXL1
gene id: 8469:MIXL1
uniprot id: M7AXN4
names: Subcellular Location Annotation
messages: Nucleus

8469:RHBG
gene id: 8469:RHBG
uniprot id: M7BGY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

8469:UCKL1
gene id: 8469:UCKL1
uniprot id: M7B835
names: Similarity
messages: Belongs to the uridine kinase family.

8469:USP49
gene id: 8469:USP49
uniprot id: M7B1F7
names: Similarity
messages: Belongs to the peptidase C19 family.

8469:LOC102932505
gene id: 8469:LOC102932505
uniprot id: M7CAQ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8469:PLN
gene id: 8469:PLN
uniprot id: M7CCZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholamban family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane
messages: Sarcoplasmic reticulum membrane

8469:LOC102932685
gene id: 8469:LOC102932685
uniprot id: M7ARA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ITPK1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.
messages: Monomer.

8469:MEIG1
gene id: 8469:MEIG1
uniprot id: M7BC14
names: Function
names: Similarity
messages: Belongs to the MEIG1 family.
messages: Essential for spermiogenesis.

8469:LOC102944483
gene id: 8469:LOC102944483
uniprot id: M7CBQ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8469:MEA1
gene id: 8469:MEA1
uniprot id: M7C7K1
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

8469:SLC35B2
gene id: 8469:SLC35B2
uniprot id: M7AJD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

8469:STX5
gene id: 8469:STX5
uniprot id: M7BCC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

8469:ACP5
gene id: 8469:ACP5
uniprot id: M7BNF1
names: Cofactor
messages: Binds 2 iron ions per subunit.

8469:LOC102946308
gene id: 8469:LOC102946308
uniprot id: M7BLT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:MAN2A1
gene id: 8469:MAN2A1
uniprot id: M7BVT9
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

8469:DRD2
gene id: 8469:DRD2
uniprot id: M7BHL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:PODXL2
gene id: 8469:PODXL2
uniprot id: M7BIV9
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102944080
gene id: 8469:LOC102944080
uniprot id: M7BZI2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:LOC102938681
gene id: 8469:LOC102938681
uniprot id: M7BHH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

8469:LOC102943241
gene id: 8469:LOC102943241
uniprot id: M7B7Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102948218
gene id: 8469:LOC102948218
uniprot id: M7AWW1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8469:ACKR3
gene id: 8469:ACKR3
uniprot id: M7BNU0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:LOC102935938
gene id: 8469:LOC102935938
uniprot id: M7AZF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:TFAP2C
gene id: 8469:TFAP2C
uniprot id: M7BF25
names: Similarity
messages: Belongs to the AP-2 family.

8469:LOC102944799
gene id: 8469:LOC102944799
uniprot id: M7AHP8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8469:SLC5A5
gene id: 8469:SLC5A5
uniprot id: M7AWG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8469:ATP6V1C2
gene id: 8469:ATP6V1C2
uniprot id: M7CLF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

8469:LOC102945011
gene id: 8469:LOC102945011
uniprot id: M7BJL6
names: Subcellular Location Annotation
messages: Membrane

8469:SLC16A3
gene id: 8469:SLC16A3
uniprot id: M7BKB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8469:LOC102938874
gene id: 8469:LOC102938874
uniprot id: M7B445
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:CHPF2
gene id: 8469:CHPF2
uniprot id: M7BDQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8469:SLC25A19
gene id: 8469:SLC25A19
uniprot id: M7AMA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8469:LOC102936658
gene id: 8469:LOC102936658
uniprot id: M7C2A3
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion intermembrane space
messages: Mitochondrion outer membrane
messages: Rough endoplasmic reticulum
messages: cilium
messages: extracellular exosome
messages: extracellular space

8469:LOC102939815
gene id: 8469:LOC102939815
uniprot id: M7BFR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8469:GPC4
gene id: 8469:GPC4
uniprot id: M7CEF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

8469:LOC102941532
gene id: 8469:LOC102941532
uniprot id: M7ARH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102935360
gene id: 8469:LOC102935360
uniprot id: M7C689
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102941854
gene id: 8469:LOC102941854
uniprot id: M7CBD9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:HTR1A
gene id: 8469:HTR1A
uniprot id: M7BPX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:PPP2R3C
gene id: 8469:PPP2R3C
uniprot id: M7B129
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8469:GRK2
gene id: 8469:GRK2
uniprot id: M7BEL5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8469:GPHA2
gene id: 8469:GPHA2
uniprot id: M7AMV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Secreted

8469:C5H9orf64
gene id: 8469:C5H9orf64
uniprot id: M7B062
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

8469:CENPM
gene id: 8469:CENPM
uniprot id: M7C161
names: Subcellular Location Annotation
messages: Nucleus

8469:COMT
gene id: 8469:COMT
uniprot id: M7BSW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.

8469:FGFBP2
gene id: 8469:FGFBP2
uniprot id: M7BRV4
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

8469:YDJC
gene id: 8469:YDJC
uniprot id: M7C6W8
names: Function
names: Similarity
messages: Belongs to the YdjC deacetylase family.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

8469:XKRX
gene id: 8469:XKRX
uniprot id: M7B270
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8469:GNL2
gene id: 8469:GNL2
uniprot id: M7BS06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

8469:REXO4
gene id: 8469:REXO4
uniprot id: M7BBU6
names: Similarity
messages: Belongs to the REXO4 family.

8469:CALCB
gene id: 8469:CALCB
uniprot id: M7CC40
names: Similarity
messages: Belongs to the calcitonin family.

8469:LOC102947999
gene id: 8469:LOC102947999
uniprot id: M7AZE2
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8469:LOC102945378
gene id: 8469:LOC102945378
uniprot id: M7BVN6
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8469:SPPL2B
gene id: 8469:SPPL2B
uniprot id: M7C603
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

8469:PDC
gene id: 8469:PDC
uniprot id: M7BLM1
names: Similarity
messages: Belongs to the phosducin family.

8469:FGF20
gene id: 8469:FGF20
uniprot id: M7AZQ0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8469:TRPC5
gene id: 8469:TRPC5
uniprot id: M7BE34
names: Subcellular Location Annotation
messages: Membrane

8469:RPS27
gene id: 8469:RPS27
uniprot id: M7B7S6
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

8469:LOC102937654
gene id: 8469:LOC102937654
uniprot id: M7B1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:LOC102940256
gene id: 8469:LOC102940256
uniprot id: M7ASR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:EPC1
gene id: 8469:EPC1
uniprot id: M7CHJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

8469:RFLNA
gene id: 8469:RFLNA
uniprot id: M7C8Z7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

8469:PMM2
gene id: 8469:PMM2
uniprot id: M7BW55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

8469:TMEM115
gene id: 8469:TMEM115
uniprot id: M7BPF6
names: Subcellular Location Annotation
messages: Membrane

8469:MRPL24
gene id: 8469:MRPL24
uniprot id: M7B0J5
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

8469:ST6GAL1
gene id: 8469:ST6GAL1
uniprot id: M7BH26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8469:FZD9
gene id: 8469:FZD9
uniprot id: M7BEH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

8469:LOC102943966
gene id: 8469:LOC102943966
uniprot id: M7AIQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

8469:LOC102945962
gene id: 8469:LOC102945962
uniprot id: M7BAX4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:INTS12
gene id: 8469:INTS12
uniprot id: M7BY76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 12 family.
messages: Nucleus

8469:LOC102934067
gene id: 8469:LOC102934067
uniprot id: M7AN52
names: Similarity
messages: Belongs to the actin family.

8469:LOC102935356
gene id: 8469:LOC102935356
uniprot id: M7CJS5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:LOC102933292
gene id: 8469:LOC102933292
uniprot id: M7AS92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8469:LOC102947282
gene id: 8469:LOC102947282
uniprot id: M7CLU0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8469:MMP9
gene id: 8469:MMP9
uniprot id: M7BJ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: extracellular matrix

8469:CALHM3
gene id: 8469:CALHM3
uniprot id: M7BZU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

8469:LOC102941370
gene id: 8469:LOC102941370
uniprot id: M7AWU3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8469:LOC102930615
gene id: 8469:LOC102930615
uniprot id: M7CK71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

8469:MARCKS
gene id: 8469:MARCKS
uniprot id: M7BQS3
names: Similarity
messages: Belongs to the MARCKS family.

8469:ZIC1
gene id: 8469:ZIC1
uniprot id: M7CHH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

8469:FAM124B
gene id: 8469:FAM124B
uniprot id: M7C9I5
names: Similarity
messages: Belongs to the FAM124 family.

8469:INSIG2
gene id: 8469:INSIG2
uniprot id: M7CC78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

8469:FAHD1
gene id: 8469:FAHD1
uniprot id: M7BXW9
names: Similarity
messages: Belongs to the FAH family.

8469:GPR65
gene id: 8469:GPR65
uniprot id: M7CEZ2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:NEUROD4
gene id: 8469:NEUROD4
uniprot id: M7AH39
names: Subcellular Location Annotation
messages: Nucleus

8469:LOC102944265
gene id: 8469:LOC102944265
uniprot id: M7BVN1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8469:HOXB13
gene id: 8469:HOXB13
uniprot id: M7BP43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8469:LOC102937870
gene id: 8469:LOC102937870
uniprot id: M7BC82
names: Subcellular Location Annotation
messages: Nucleus

8469:NME6
gene id: 8469:NME6
uniprot id: M7B1D7
names: Similarity
messages: Belongs to the NDK family.

8469:LOC102941785
gene id: 8469:LOC102941785
uniprot id: M7C218
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

8469:TMSB4X
gene id: 8469:TMSB4X
uniprot id: M7BE97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

8469:LOC102937339
gene id: 8469:LOC102937339
uniprot id: M7BDY9
names: Similarity
messages: Belongs to the TGF-beta family.

8469:SCRN3
gene id: 8469:SCRN3
uniprot id: M7BSM7
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

8469:DNAJB14
gene id: 8469:DNAJB14
uniprot id: M7B6U2
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102940064
gene id: 8469:LOC102940064
uniprot id: M7CF67
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

8469:BOK
gene id: 8469:BOK
uniprot id: M7B8Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

8469:LOC102937832
gene id: 8469:LOC102937832
uniprot id: M7AUS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:LOC102935416
gene id: 8469:LOC102935416
uniprot id: M7B2U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:RPL13
gene id: 8469:RPL13
uniprot id: M7BGE2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

8469:LOC102934000
gene id: 8469:LOC102934000
uniprot id: M7BVV2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:ETF1
gene id: 8469:ETF1
uniprot id: M7AK59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

8469:KCNJ9
gene id: 8469:KCNJ9
uniprot id: M7AWZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8469:NDUFA2
gene id: 8469:NDUFA2
uniprot id: M7BEI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8469:SLC25A24
gene id: 8469:SLC25A24
uniprot id: M7C6F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8469:LOC102935676
gene id: 8469:LOC102935676
uniprot id: M7C3Y5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:ZDHHC24
gene id: 8469:ZDHHC24
uniprot id: M7BCB9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8469:POPDC3
gene id: 8469:POPDC3
uniprot id: M7BLC2
names: Similarity
messages: Belongs to the popeye family.

8469:BARHL2
gene id: 8469:BARHL2
uniprot id: M7ARY3
names: Subcellular Location Annotation
messages: Nucleus

8469:CALHM2
gene id: 8469:CALHM2
uniprot id: M7BI63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

8469:CRK
gene id: 8469:CRK
uniprot id: M7C0H1
names: Similarity
messages: Belongs to the CRK family.

8469:ST3GAL2
gene id: 8469:ST3GAL2
uniprot id: M7AYA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8469:SERPINH1
gene id: 8469:SERPINH1
uniprot id: M7B8L2
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

8469:LOC102946766
gene id: 8469:LOC102946766
uniprot id: M7C1D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102946429
gene id: 8469:LOC102946429
uniprot id: M7B8F9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8469:DUSP3
gene id: 8469:DUSP3
uniprot id: M7BRL7
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8469:LOC102937127
gene id: 8469:LOC102937127
uniprot id: M7B3F1
names: Similarity
messages: Belongs to the serpin family.

8469:AGPAT3
gene id: 8469:AGPAT3
uniprot id: M7B315
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8469:RBCK1
gene id: 8469:RBCK1
uniprot id: M7BCE6
names: Similarity
messages: Belongs to the RBR family.

8469:ALDH3B1
gene id: 8469:ALDH3B1
uniprot id: M7BHF7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8469:STOML3
gene id: 8469:STOML3
uniprot id: M7AZV6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8469:MED18
gene id: 8469:MED18
uniprot id: M7B0Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8469:TENT5D
gene id: 8469:TENT5D
uniprot id: M7BQ14
names: Similarity
messages: Belongs to the TENT family.

8469:LOC102936290
gene id: 8469:LOC102936290
uniprot id: M7B8H4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:LOC102941961
gene id: 8469:LOC102941961
uniprot id: M7B1Z7
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

8469:GPD2
gene id: 8469:GPD2
uniprot id: M7CDA7
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

8469:LOC102936306
gene id: 8469:LOC102936306
uniprot id: M7B8K4
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

8469:KEF27 p10
gene id: 8469:KEF27_p10
uniprot id: Q9XPI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8469:RPE
gene id: 8469:RPE
uniprot id: M7ANI0
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

8469:LOC102942116
gene id: 8469:LOC102942116
uniprot id: M7AS78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPACA4/bouncer family.
messages: Cell membrane
messages: Membrane

8469:GRINA
gene id: 8469:GRINA
uniprot id: M7AWR7
names: Subcellular Location Annotation
messages: Membrane

8469:CPEB4
gene id: 8469:CPEB4
uniprot id: M7BNA4
names: Similarity
messages: Belongs to the RRM CPEB family.

8469:TMED6
gene id: 8469:TMED6
uniprot id: M7BCS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8469:LOC102931399
gene id: 8469:LOC102931399
uniprot id: M7B696
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8469:LOC102933737
gene id: 8469:LOC102933737
uniprot id: M7AZI3
names: Similarity
messages: Belongs to the serpin family.

8469:MFSD3
gene id: 8469:MFSD3
uniprot id: M7BKE4
names: Subcellular Location Annotation
messages: Membrane

8469:REM1
gene id: 8469:REM1
uniprot id: M7BCE1
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

8469:ZDHHC23
gene id: 8469:ZDHHC23
uniprot id: M7B6S2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8469:HAUS3
gene id: 8469:HAUS3
uniprot id: M7BND5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

8469:STAR
gene id: 8469:STAR
uniprot id: M7CAM7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

8469:RPL19
gene id: 8469:RPL19
uniprot id: M7BPA7
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

8469:BLOC1S2
gene id: 8469:BLOC1S2
uniprot id: M7ASW3
names: Similarity
messages: Belongs to the BLOC1S2 family.

8469:POLR2E
gene id: 8469:POLR2E
uniprot id: M7AGU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

8469:LOC102940602
gene id: 8469:LOC102940602
uniprot id: M7C3W5
names: Similarity
messages: Belongs to the SLITRK family.

8469:LOC102939121
gene id: 8469:LOC102939121
uniprot id: M7BYT9
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102937007
gene id: 8469:LOC102937007
uniprot id: M7B8L9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

8469:LOC102943220
gene id: 8469:LOC102943220
uniprot id: M7BKL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histone H4 family.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:OLFM1
gene id: 8469:OLFM1
uniprot id: M7BG89
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8469:TMEM177
gene id: 8469:TMEM177
uniprot id: M7C1V9
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

8469:LOC102946497
gene id: 8469:LOC102946497
uniprot id: M7BE56
names: Similarity
messages: Belongs to the globin family.

8469:LOC102946652
gene id: 8469:LOC102946652
uniprot id: M7AUT4
names: Similarity
messages: Belongs to the SCO1/2 family.

8469:OLFML3
gene id: 8469:OLFML3
uniprot id: M7C631
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OLFML3 family.
messages: Secreted

8469:IFT46
gene id: 8469:IFT46
uniprot id: M7B630
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT46 family.
messages: cilium
messages: cilium basal body

8469:HMGCS2
gene id: 8469:HMGCS2
uniprot id: M7BR31
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

8469:LRRC14
gene id: 8469:LRRC14
uniprot id: M7BAA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRAME family. LRRC14 subfamily.
messages: Cytoplasm

8469:GPR182
gene id: 8469:GPR182
uniprot id: M7AV96
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:LOC102933066
gene id: 8469:LOC102933066
uniprot id: M7B956
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:TOB2
gene id: 8469:TOB2
uniprot id: M7CL44
names: Similarity
messages: Belongs to the BTG family.

8469:ASCC1
gene id: 8469:ASCC1
uniprot id: M7AWV7
names: Subcellular Location Annotation
messages: Cytoplasm

8469:PSPN
gene id: 8469:PSPN
uniprot id: M7AVY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

8469:PTGES2
gene id: 8469:PTGES2
uniprot id: M7BLL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

8469:LOC102934018
gene id: 8469:LOC102934018
uniprot id: M7BVY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

8469:RPL3
gene id: 8469:RPL3
uniprot id: M7AQW1
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

8469:TMBIM1
gene id: 8469:TMBIM1
uniprot id: M7BST6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8469:LOC102939630
gene id: 8469:LOC102939630
uniprot id: M7BRG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

8469:NES
gene id: 8469:NES
uniprot id: M7B0J1
names: Similarity
messages: Belongs to the intermediate filament family.

8469:ANAPC5
gene id: 8469:ANAPC5
uniprot id: M7C917
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

8469:CDC6
gene id: 8469:CDC6
uniprot id: M7C0G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
messages: Nucleus

8469:EMX2
gene id: 8469:EMX2
uniprot id: M7BU86
names: Subcellular Location Annotation
messages: Nucleus

8469:LOC102930697
gene id: 8469:LOC102930697
uniprot id: M7BVJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102930242
gene id: 8469:LOC102930242
uniprot id: M7ARF2
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102942255
gene id: 8469:LOC102942255
uniprot id: M7AVM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Component of the 40S small ribosomal subunit.
messages: Rough endoplasmic reticulum

8469:PCYOX1
gene id: 8469:PCYOX1
uniprot id: M7B0F2
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

8469:RDH10
gene id: 8469:RDH10
uniprot id: M7B319
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8469:LOC102934321
gene id: 8469:LOC102934321
uniprot id: M7BN89
names: Similarity
messages: Belongs to the FBPase class 1 family.

8469:ACY3
gene id: 8469:ACY3
uniprot id: M7CF51
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

8469:SFRP2
gene id: 8469:SFRP2
uniprot id: M7AKI8
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8469:LOC102943327
gene id: 8469:LOC102943327
uniprot id: M7C284
names: Similarity
messages: Belongs to the ATG8 family.

8469:HAPLN3
gene id: 8469:HAPLN3
uniprot id: M7BHV5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8469:NOG
gene id: 8469:NOG
uniprot id: M7BSM5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

8469:SSTR2
gene id: 8469:SSTR2
uniprot id: M7BN70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

8469:HOXD10
gene id: 8469:HOXD10
uniprot id: M7BD26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8469:LOC102946962
gene id: 8469:LOC102946962
uniprot id: M7AKT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8469:MRPL49
gene id: 8469:MRPL49
uniprot id: M7AMT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

8469:LOC102947119
gene id: 8469:LOC102947119
uniprot id: M7ALT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

8469:RAB3D
gene id: 8469:RAB3D
uniprot id: M7BNG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

8469:YWHAH
gene id: 8469:YWHAH
uniprot id: M7BQ32
names: Similarity
messages: Belongs to the 14-3-3 family.

8469:APEX1
gene id: 8469:APEX1
uniprot id: M7AIU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

8469:CTPS1
gene id: 8469:CTPS1
uniprot id: M7BCT2
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

8469:CHST1
gene id: 8469:CHST1
uniprot id: M7BAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8469:GJB1
gene id: 8469:GJB1
uniprot id: M7BMP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8469:LOC102936460
gene id: 8469:LOC102936460
uniprot id: M7APB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8469:PTP4A2
gene id: 8469:PTP4A2
uniprot id: M7C3A7
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8469:LOC102936924
gene id: 8469:LOC102936924
uniprot id: M7ANA3
names: Subcellular Location Annotation
messages: Membrane

8469:SOX11
gene id: 8469:SOX11
uniprot id: M7BXT1
names: Subcellular Location Annotation
messages: Nucleus

8469:MTHFR
gene id: 8469:MTHFR
uniprot id: M7BWD2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

8469:CCN2
gene id: 8469:CCN2
uniprot id: M7BD58
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8469:LOC102943084
gene id: 8469:LOC102943084
uniprot id: M7ALZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:CYGB
gene id: 8469:CYGB
uniprot id: M7B688
names: Similarity
messages: Belongs to the globin family.

8469:LMOD2
gene id: 8469:LMOD2
uniprot id: M7B635
names: Subcellular Location Annotation
messages: cytoskeleton

8469:LOC102942139
gene id: 8469:LOC102942139
uniprot id: M7CHM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:AMIGO2
gene id: 8469:AMIGO2
uniprot id: M7BIP7
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

8469:CDC26
gene id: 8469:CDC26
uniprot id: M7AUI7
names: Similarity
messages: Belongs to the CDC26 family.

8469:RNF182
gene id: 8469:RNF182
uniprot id: M7BT69
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

8469:LOC102933472
gene id: 8469:LOC102933472
uniprot id: M7C851
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8469:CFAP45
gene id: 8469:CFAP45
uniprot id: M7AWW4
names: Similarity
messages: Belongs to the CFAP45 family.

8469:MSX1
gene id: 8469:MSX1
uniprot id: M7BXN9
names: Subcellular Location Annotation
messages: Nucleus

8469:OTUD7A
gene id: 8469:OTUD7A
uniprot id: M7C023
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8469:LOC102947713
gene id: 8469:LOC102947713
uniprot id: M7ATG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:SAP30L
gene id: 8469:SAP30L
uniprot id: M7BMV9
names: Similarity
messages: Belongs to the SAP30 family.

8469:NGFR
gene id: 8469:NGFR
uniprot id: M7BP26
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8469:COQ8A
gene id: 8469:COQ8A
uniprot id: M7AXM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane
messages: Mitochondrion

8469:LOC102940905
gene id: 8469:LOC102940905
uniprot id: M7AUG1
names: Similarity
messages: Belongs to the protein kinase superfamily.

8469:UTP14A
gene id: 8469:UTP14A
uniprot id: M7B2H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

8469:GDF9
gene id: 8469:GDF9
uniprot id: M7B555
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

8469:LOC102934239
gene id: 8469:LOC102934239
uniprot id: M7BV34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with VGF-derived peptide TLQP-21.
messages: Membrane
messages: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

8469:SIX1
gene id: 8469:SIX1
uniprot id: M7BEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Cytoplasm
messages: Nucleus

8469:THNSL1
gene id: 8469:THNSL1
uniprot id: M7C8V3
names: Similarity
messages: Belongs to the threonine synthase family.

8469:LOC102939605
gene id: 8469:LOC102939605
uniprot id: M7B4V0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:KCNJ13
gene id: 8469:KCNJ13
uniprot id: M7BXP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8469:PTX4
gene id: 8469:PTX4
uniprot id: M7AXH2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8469:YIPF3
gene id: 8469:YIPF3
uniprot id: M7AXG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
messages: Membrane
messages: cis-Golgi network membrane

8469:HSP90AB1
gene id: 8469:HSP90AB1
uniprot id: M7AXI1
names: Similarity
messages: Belongs to the heat shock protein 90 family.

8469:YARS1
gene id: 8469:YARS1
uniprot id: M7ASU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus

8469:SUB1
gene id: 8469:SUB1
uniprot id: M7ANA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Nucleus

8469:LOC102935780
gene id: 8469:LOC102935780
uniprot id: M7BFE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8469:NEFL
gene id: 8469:NEFL
uniprot id: M7AY91
names: Similarity
messages: Belongs to the intermediate filament family.

8469:LOC102939434
gene id: 8469:LOC102939434
uniprot id: M7C6U4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8469:VAT1
gene id: 8469:VAT1
uniprot id: M7CHW5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8469:RRAGC
gene id: 8469:RRAGC
uniprot id: M7BFV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

8469:KCNJ5
gene id: 8469:KCNJ5
uniprot id: M7BN24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

8469:CHMP2B
gene id: 8469:CHMP2B
uniprot id: M7BGS9
names: Similarity
messages: Belongs to the SNF7 family.

8469:LOC102947196
gene id: 8469:LOC102947196
uniprot id: M7AVN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

8469:LOC102936619
gene id: 8469:LOC102936619
uniprot id: M7B8W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8469:AMER1
gene id: 8469:AMER1
uniprot id: M7BII3
names: Similarity
messages: Belongs to the Amer family.

8469:C2H18orf21
gene id: 8469:C2H18orf21
uniprot id: M7ANZ0
names: Similarity
messages: Belongs to the UPF0711 family.

8469:PPM1D
gene id: 8469:PPM1D
uniprot id: M7C035
names: Similarity
messages: Belongs to the PP2C family.

8469:LOC102934956
gene id: 8469:LOC102934956
uniprot id: M7AVI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8469:TMEM170B
gene id: 8469:TMEM170B
uniprot id: M7ARW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

8469:SOX14
gene id: 8469:SOX14
uniprot id: M7BMH0
names: Subcellular Location Annotation
messages: Nucleus

8469:RMI1
gene id: 8469:RMI1
uniprot id: M7BQJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RMI1 family.
messages: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
messages: Nucleus

8469:KEF27 p11
gene id: 8469:KEF27_p11
uniprot id: Q9XPI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8469:DPAGT1
gene id: 8469:DPAGT1
uniprot id: M7BCW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

8469:FUT3
gene id: 8469:FUT3
uniprot id: M7B7L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8469:LOC102944933
gene id: 8469:LOC102944933
uniprot id: M7BW91
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102945823
gene id: 8469:LOC102945823
uniprot id: M7AKA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:DYNLL2
gene id: 8469:DYNLL2
uniprot id: M7BPR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8469:LIG4
gene id: 8469:LIG4
uniprot id: M7CF39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

8469:ACTRT3
gene id: 8469:ACTRT3
uniprot id: M7C5U4
names: Similarity
messages: Belongs to the actin family.

8469:HHEX
gene id: 8469:HHEX
uniprot id: M7C1S8
names: Subcellular Location Annotation
messages: Nucleus

8469:KEF27 p13
gene id: 8469:KEF27_p13
uniprot id: Q9XPI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

8469:GALK1
gene id: 8469:GALK1
uniprot id: M7AVK1
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

8469:LOC102935080
gene id: 8469:LOC102935080
uniprot id: M7BS36
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:TNIP2
gene id: 8469:TNIP2
uniprot id: M7BC68
names: Subcellular Location Annotation
messages: Cytoplasm

8469:LOC102937384
gene id: 8469:LOC102937384
uniprot id: M7APT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8469:TMEM198
gene id: 8469:TMEM198
uniprot id: M7AVI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

8469:LOC102941073
gene id: 8469:LOC102941073
uniprot id: M7AME3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:DYNLT4
gene id: 8469:DYNLT4
uniprot id: M7B7Y2
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8469:C12H19orf12
gene id: 8469:C12H19orf12
uniprot id: M7BI75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

8469:DESI1
gene id: 8469:DESI1
uniprot id: M7CB05
names: Similarity
messages: Belongs to the DeSI family.

8469:UBALD2
gene id: 8469:UBALD2
uniprot id: M7AHI1
names: Similarity
messages: Belongs to the UBALD family.

8469:MRPS25
gene id: 8469:MRPS25
uniprot id: M7BU11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

8469:LOC102944926
gene id: 8469:LOC102944926
uniprot id: M7AM47
names: Subcellular Location Annotation
messages: Membrane

8469:HTR1E
gene id: 8469:HTR1E
uniprot id: M7C326
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:NIPAL3
gene id: 8469:NIPAL3
uniprot id: M7B781
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8469:FAM214B
gene id: 8469:FAM214B
uniprot id: M7CF19
names: Similarity
messages: Belongs to the FAM214 family.

8469:LOC102946144
gene id: 8469:LOC102946144
uniprot id: M7B7N0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:KCNJ2
gene id: 8469:KCNJ2
uniprot id: M7BU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Membrane

8469:PIGH
gene id: 8469:PIGH
uniprot id: M7BSU9
names: Similarity
messages: Belongs to the PIGH family.

8469:LOC102930994
gene id: 8469:LOC102930994
uniprot id: M7BMM0
names: Subcellular Location Annotation
messages: Membrane

8469:NR4A2
gene id: 8469:NR4A2
uniprot id: M7C2X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

8469:TLR8
gene id: 8469:TLR8
uniprot id: M7BTT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8469:GALNT5
gene id: 8469:GALNT5
uniprot id: M7BSL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8469:LOC102931559
gene id: 8469:LOC102931559
uniprot id: M7AT38
names: Similarity
messages: Belongs to the cytochrome P450 family.

8469:ZDHHC12
gene id: 8469:ZDHHC12
uniprot id: M7BJM7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8469:LOC102937140
gene id: 8469:LOC102937140
uniprot id: M7B6Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8469:LOC102941633
gene id: 8469:LOC102941633
uniprot id: M7C4F9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:LGI2
gene id: 8469:LGI2
uniprot id: M7BJM1
names: Subcellular Location Annotation
messages: Secreted

8469:GHSR
gene id: 8469:GHSR
uniprot id: M7AWD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).

8469:LOC102936683
gene id: 8469:LOC102936683
uniprot id: M7B4M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8469:MLNR
gene id: 8469:MLNR
uniprot id: M7AGC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:METTL1
gene id: 8469:METTL1
uniprot id: M7B0P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Nucleus

8469:MON1A
gene id: 8469:MON1A
uniprot id: M7BZB0
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

8469:LOC102946876
gene id: 8469:LOC102946876
uniprot id: A0A8K0YBE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

8469:EHD3
gene id: 8469:EHD3
uniprot id: M7AXM6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

8469:LOC102937851
gene id: 8469:LOC102937851
uniprot id: M7CKK5
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8469:LOC102947558
gene id: 8469:LOC102947558
uniprot id: M7AJY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:ENPP5
gene id: 8469:ENPP5
uniprot id: M7B7S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Cell membrane
messages: Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
messages: Membrane

8469:LOC102936508
gene id: 8469:LOC102936508
uniprot id: M7B8H4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:LOC102946462
gene id: 8469:LOC102946462
uniprot id: M7BHJ9
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

8469:POU1F1
gene id: 8469:POU1F1
uniprot id: M7BCA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-1 subfamily.
messages: Nucleus

8469:REEP2
gene id: 8469:REEP2
uniprot id: M7AZE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

8469:LOC102934233
gene id: 8469:LOC102934233
uniprot id: M7BZN9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:FZD10
gene id: 8469:FZD10
uniprot id: M7BT01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

8469:RPS6KB1
gene id: 8469:RPS6KB1
uniprot id: M7CAP2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8469:MID1IP1
gene id: 8469:MID1IP1
uniprot id: M7B7V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

8469:RPL23
gene id: 8469:RPL23
uniprot id: M7C0D4
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

8469:LOC102934368
gene id: 8469:LOC102934368
uniprot id: M7BAD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:METTL3
gene id: 8469:METTL3
uniprot id: M7APW1
names: Similarity
messages: Belongs to the MT-A70-like family.

8469:SERPING1
gene id: 8469:SERPING1
uniprot id: M7BHD4
names: Similarity
messages: Belongs to the serpin family.

8469:LOC102939759
gene id: 8469:LOC102939759
uniprot id: M7ALG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:LOC102930690
gene id: 8469:LOC102930690
uniprot id: M7CAF6
names: Subcellular Location Annotation
messages: Membrane

8469:VPS37D
gene id: 8469:VPS37D
uniprot id: M7APQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

8469:KEF27 p08
gene id: 8469:KEF27_p08
uniprot id: Q9XPI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

8469:GALR3
gene id: 8469:GALR3
uniprot id: M7BFM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8469:CHST3
gene id: 8469:CHST3
uniprot id: M7BRR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8469:LOC102946134
gene id: 8469:LOC102946134
uniprot id: M7AR97
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:GALNT1
gene id: 8469:GALNT1
uniprot id: M7C7Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8469:LOC102939543
gene id: 8469:LOC102939543
uniprot id: M7BCS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:CCT5
gene id: 8469:CCT5
uniprot id: M7CAI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8469:ZC3H12B
gene id: 8469:ZC3H12B
uniprot id: M7BBZ7
names: Similarity
messages: Belongs to the ZC3H12 family.

8469:LOC102946819
gene id: 8469:LOC102946819
uniprot id: M7BAF2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8469:HYLS1
gene id: 8469:HYLS1
uniprot id: M7BBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

8469:LOC102939665
gene id: 8469:LOC102939665
uniprot id: M7B584
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8469:LOC102938947
gene id: 8469:LOC102938947
uniprot id: M7AWS6
names: Similarity
messages: Belongs to the perilipin family.

8469:BFSP1
gene id: 8469:BFSP1
uniprot id: M7B8A4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cell cortex
messages: cytoskeleton

8469:SMC2
gene id: 8469:SMC2
uniprot id: M7AYY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Chromosome
messages: Nucleus

8469:TMEM121
gene id: 8469:TMEM121
uniprot id: M7AGD0
names: Similarity
messages: Belongs to the TMEM121 family.

8469:MB21D2
gene id: 8469:MB21D2
uniprot id: M7BIB5
names: Similarity
messages: Belongs to the mab-21 family.

8469:RNASEH2A
gene id: 8469:RNASEH2A
uniprot id: M7BYS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

8469:ZDHHC7
gene id: 8469:ZDHHC7
uniprot id: M7C6P4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8469:LOC102936238
gene id: 8469:LOC102936238
uniprot id: M7AVM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8469:SIX3
gene id: 8469:SIX3
uniprot id: M7BAQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

8469:HSPB3
gene id: 8469:HSPB3
uniprot id: M7CCF3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8469:WNT5B
gene id: 8469:WNT5B
uniprot id: M7AJV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8469:SNU13
gene id: 8469:SNU13
uniprot id: M7C157
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

8469:LOC102934412
gene id: 8469:LOC102934412
uniprot id: M7B6L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102931635
gene id: 8469:LOC102931635
uniprot id: M7B8R1
names: Similarity
messages: Belongs to the peptidase C14A family.

8469:EOMES
gene id: 8469:EOMES
uniprot id: M7AX15
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8469:NMBR
gene id: 8469:NMBR
uniprot id: M7CE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:STOML2
gene id: 8469:STOML2
uniprot id: M7BNI0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8469:PURG
gene id: 8469:PURG
uniprot id: M7BBK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

8469:RPL8
gene id: 8469:RPL8
uniprot id: M7B334
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

8469:LOC102939003
gene id: 8469:LOC102939003
uniprot id: M7ATB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

8469:LOC102939974
gene id: 8469:LOC102939974
uniprot id: M7BCS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:IGFBP4
gene id: 8469:IGFBP4
uniprot id: M7B7E5
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8469:SRPX2
gene id: 8469:SRPX2
uniprot id: M7B265
names: Caution
names: Subcellular Location Annotation
messages: Cell surface
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Synapse

8469:LOC102937000
gene id: 8469:LOC102937000
uniprot id: M7BC99
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8469:LOC102930351
gene id: 8469:LOC102930351
uniprot id: M7B989
names: Subcellular Location Annotation
messages: Membrane
messages: chromaffin granule membrane

8469:MYADM
gene id: 8469:MYADM
uniprot id: M7AM33
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102935545
gene id: 8469:LOC102935545
uniprot id: M7B7H6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8469:LOC102937427
gene id: 8469:LOC102937427
uniprot id: M7BUQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8469:KEF27 p04
gene id: 8469:KEF27_p04
uniprot id: Q9XPH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

8469:IDH2
gene id: 8469:IDH2
uniprot id: M7BDM6
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

8469:CAMK2N2
gene id: 8469:CAMK2N2
uniprot id: M7AWR9
names: Similarity
messages: Belongs to the CAMK2N family.

8469:LOC102935129
gene id: 8469:LOC102935129
uniprot id: M7BZL1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:ATF4
gene id: 8469:ATF4
uniprot id: M7CL26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

8469:LOC102944761
gene id: 8469:LOC102944761
uniprot id: M7BUE3
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

8469:HTRA2
gene id: 8469:HTRA2
uniprot id: M7BCH5
names: Similarity
messages: Belongs to the peptidase S1C family.

8469:TMEM35A
gene id: 8469:TMEM35A
uniprot id: M7B4D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

8469:LOC102935860
gene id: 8469:LOC102935860
uniprot id: M7ARV0
names: Similarity
names: Subunit
messages: Belongs to the TRIM/RBCC family.
messages: Interacts with IFNAR1; this interaction prevents association of IFNAR1 with TYK2.

8469:UTP3
gene id: 8469:UTP3
uniprot id: M7BPN6
names: Similarity
messages: Belongs to the SAS10 family.

8469:LOC102936331
gene id: 8469:LOC102936331
uniprot id: M7BWN3
names: Subcellular Location Annotation
messages: Membrane

8469:GREM1
gene id: 8469:GREM1
uniprot id: M7BEX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

8469:ABRACL
gene id: 8469:ABRACL
uniprot id: M7BNZ4
names: Similarity
messages: Belongs to the costars family.

8469:LOC102934932
gene id: 8469:LOC102934932
uniprot id: M7BUP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8469:ADORA2B
gene id: 8469:ADORA2B
uniprot id: M7CAT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

8469:EMC8
gene id: 8469:EMC8
uniprot id: M7BGB2
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

8469:UBE4A
gene id: 8469:UBE4A
uniprot id: M7B625
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

8469:UCK2
gene id: 8469:UCK2
uniprot id: M7C275
names: Similarity
names: Subunit
messages: Belongs to the uridine kinase family.
messages: Homotetramer.

8469:SOSTDC1
gene id: 8469:SOSTDC1
uniprot id: M7B3C1
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8469:KCNV1
gene id: 8469:KCNV1
uniprot id: M7BJ50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
messages: Heteromultimer with KCNB1 and KCNB2. Interacts with KCNC4 and KCND1.
messages: Membrane
messages: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.

8469:LOC102930998
gene id: 8469:LOC102930998
uniprot id: M7CAI3
names: Subcellular Location Annotation
messages: Membrane

8469:RARRES1
gene id: 8469:RARRES1
uniprot id: M7BX92
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

8469:ACTG1
gene id: 8469:ACTG1
uniprot id: M7AJL3
names: Similarity
messages: Belongs to the actin family.

8469:NEUROD1
gene id: 8469:NEUROD1
uniprot id: M7BDT2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8469:ETV3
gene id: 8469:ETV3
uniprot id: M7B0K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity.

8469:ADM
gene id: 8469:ADM
uniprot id: M7CC73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

8469:HSPB1
gene id: 8469:HSPB1
uniprot id: M7BL24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

8469:LOC102948240
gene id: 8469:LOC102948240
uniprot id: M7BB22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:KTI12
gene id: 8469:KTI12
uniprot id: M7BD97
names: Similarity
messages: Belongs to the KTI12 family.

8469:IRGC
gene id: 8469:IRGC
uniprot id: M7CHY5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

8469:LARP7
gene id: 8469:LARP7
uniprot id: M7BUF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LARP7 family.
messages: nucleoplasm

8469:AMOT
gene id: 8469:AMOT
uniprot id: M7BTM5
names: Similarity
messages: Belongs to the angiomotin family.

8469:NDE1
gene id: 8469:NDE1
uniprot id: M7BNS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

8469:FAM136A
gene id: 8469:FAM136A
uniprot id: M7AYB2
names: Similarity
messages: Belongs to the FAM136 family.

8469:LOC102931845
gene id: 8469:LOC102931845
uniprot id: M7B416
names: Similarity
messages: Belongs to the osteocalcin/matrix Gla protein family.

8469:LOC102936056
gene id: 8469:LOC102936056
uniprot id: M7B445
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:KLC2
gene id: 8469:KLC2
uniprot id: M7BMY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8469:P2RX5
gene id: 8469:P2RX5
uniprot id: M7C087
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8469:DDOST
gene id: 8469:DDOST
uniprot id: M7BXY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

8469:HPD
gene id: 8469:HPD
uniprot id: M7C925
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

8469:LOC102937538
gene id: 8469:LOC102937538
uniprot id: M7API2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:BTK
gene id: 8469:BTK
uniprot id: M7B279
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8469:LOC102932936
gene id: 8469:LOC102932936
uniprot id: M7CKM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102939959
gene id: 8469:LOC102939959
uniprot id: M7BCY2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

8469:HEATR5B
gene id: 8469:HEATR5B
uniprot id: M7BP36
names: Similarity
messages: Belongs to the HEATR5 family.

8469:ACTB
gene id: 8469:ACTB
uniprot id: M7B7E7
names: Similarity
messages: Belongs to the actin family.

8469:PPCS
gene id: 8469:PPCS
uniprot id: M7B5A5
names: Similarity
messages: Belongs to the PPC synthetase family.

8469:DDAH1
gene id: 8469:DDAH1
uniprot id: M7BGM5
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

8469:CANT1
gene id: 8469:CANT1
uniprot id: M7B4I6
names: Similarity
messages: Belongs to the apyrase family.

8469:HYAL2
gene id: 8469:HYAL2
uniprot id: M7C0I1
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8469:LOC102932169
gene id: 8469:LOC102932169
uniprot id: M7BF05
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:GALR2
gene id: 8469:GALR2
uniprot id: M7AFZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8469:YES1
gene id: 8469:YES1
uniprot id: M7B6H4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8469:PARP3
gene id: 8469:PARP3
uniprot id: M7BPG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

8469:CACNG1
gene id: 8469:CACNG1
uniprot id: M7BSI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

8469:NFYA
gene id: 8469:NFYA
uniprot id: M7BW76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

8469:LOC102941459
gene id: 8469:LOC102941459
uniprot id: M7C299
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

8469:ADORA3
gene id: 8469:ADORA3
uniprot id: M7BV73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

8469:CEP19
gene id: 8469:CEP19
uniprot id: M7BKK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

8469:LOC102932794
gene id: 8469:LOC102932794
uniprot id: M7BTQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8469:TIMM17B
gene id: 8469:TIMM17B
uniprot id: M7AP75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

8469:FIGNL1
gene id: 8469:FIGNL1
uniprot id: M7B8R9
names: Similarity
messages: Belongs to the AAA ATPase family.

8469:LOC102946737
gene id: 8469:LOC102946737
uniprot id: M7B9F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102942815
gene id: 8469:LOC102942815
uniprot id: M7BJW7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:TMEM19
gene id: 8469:TMEM19
uniprot id: M7BXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

8469:LOC102933045
gene id: 8469:LOC102933045
uniprot id: M7BZZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8469:LOC102940525
gene id: 8469:LOC102940525
uniprot id: M7B7U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Has antiviral activities.
messages: Secreted

8469:LOC102935401
gene id: 8469:LOC102935401
uniprot id: M7AZ42
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

8469:LOC102944251
gene id: 8469:LOC102944251
uniprot id: M7BBH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:DDT
gene id: 8469:DDT
uniprot id: M7BVI0
names: Similarity
messages: Belongs to the MIF family.

8469:LOC102933568
gene id: 8469:LOC102933568
uniprot id: M7BN58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8469:BATF
gene id: 8469:BATF
uniprot id: M7B589
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

8469:ZHX2
gene id: 8469:ZHX2
uniprot id: M7BA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8469:THBS4
gene id: 8469:THBS4
uniprot id: M7BH55
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8469:EIF1AD
gene id: 8469:EIF1AD
uniprot id: M7BMU4
names: Similarity
messages: Belongs to the EIF1AD family.

8469:PHF5A
gene id: 8469:PHF5A
uniprot id: M7CB01
names: Similarity
messages: Belongs to the PHF5 family.

8469:SLC25A29
gene id: 8469:SLC25A29
uniprot id: M7BFX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8469:LOC102947810
gene id: 8469:LOC102947810
uniprot id: M7BSB3
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8469:GPRIN3
gene id: 8469:GPRIN3
uniprot id: M7AV78
names: Function
messages: May be involved in neurite outgrowth.

8469:TRMT6
gene id: 8469:TRMT6
uniprot id: M7ART7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

8469:LOC102931609
gene id: 8469:LOC102931609
uniprot id: M7C4I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

8469:ATP6V1G3
gene id: 8469:ATP6V1G3
uniprot id: M7B9H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8469:LOC102945425
gene id: 8469:LOC102945425
uniprot id: M7B1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:ZC2HC1C
gene id: 8469:ZC2HC1C
uniprot id: M7AYR2
names: Similarity
messages: Belongs to the ZC2HC1 family.

8469:LOC102939096
gene id: 8469:LOC102939096
uniprot id: M7BCS0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:LOC102939129
gene id: 8469:LOC102939129
uniprot id: M7BV55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8469:C2H5orf22
gene id: 8469:C2H5orf22
uniprot id: M7BM31
names: Similarity
messages: Belongs to the UPF0489 family.

8469:LOC102939324
gene id: 8469:LOC102939324
uniprot id: M7B445
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:LOC102936858
gene id: 8469:LOC102936858
uniprot id: M7CB36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102930947
gene id: 8469:LOC102930947
uniprot id: M7BT82
names: Subcellular Location Annotation
messages: Membrane

8469:CTSB
gene id: 8469:CTSB
uniprot id: M7B504
names: Similarity
messages: Belongs to the peptidase C1 family.

8469:LOC102938783
gene id: 8469:LOC102938783
uniprot id: M7AT13
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

8469:BEST4
gene id: 8469:BEST4
uniprot id: M7BPY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

8469:LOC102941440
gene id: 8469:LOC102941440
uniprot id: M7API4
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

8469:RIOX2
gene id: 8469:RIOX2
uniprot id: M7CB33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. MINA53 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
messages: nucleolus

8469:TOMM20
gene id: 8469:TOMM20
uniprot id: M7B558
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

8469:EMG1
gene id: 8469:EMG1
uniprot id: M7APJ2
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

8469:LOC102946609
gene id: 8469:LOC102946609
uniprot id: M7C659
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

8469:XKR9
gene id: 8469:XKR9
uniprot id: M7BTP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8469:SBK1
gene id: 8469:SBK1
uniprot id: M7BSK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

8469:TNFSF14
gene id: 8469:TNFSF14
uniprot id: M7BH91
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8469:KL
gene id: 8469:KL
uniprot id: M7AX20
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

8469:SCG2
gene id: 8469:SCG2
uniprot id: M7BNI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

8469:LOC102947095
gene id: 8469:LOC102947095
uniprot id: M7BM62
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.

8469:CLPS
gene id: 8469:CLPS
uniprot id: M7BK03
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

8469:LACC1
gene id: 8469:LACC1
uniprot id: M7BQM7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

8469:CRYBA2
gene id: 8469:CRYBA2
uniprot id: M7BHR7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8469:EME1
gene id: 8469:EME1
uniprot id: M7BX91
names: Similarity
messages: Belongs to the EME1/MMS4 family.

8469:KRTCAP3
gene id: 8469:KRTCAP3
uniprot id: M7BQC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

8469:SLC20A2
gene id: 8469:SLC20A2
uniprot id: M7AQV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

8469:LOC102938446
gene id: 8469:LOC102938446
uniprot id: M7BXH6
names: Subcellular Location Annotation
messages: Membrane

8469:HMGB2
gene id: 8469:HMGB2
uniprot id: M7B0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

8469:FGFBP1
gene id: 8469:FGFBP1
uniprot id: M7C637
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

8469:WARS2
gene id: 8469:WARS2
uniprot id: M7BIV6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8469:ACTA1
gene id: 8469:ACTA1
uniprot id: M7AKZ6
names: Similarity
messages: Belongs to the actin family.

8469:LOC102930068
gene id: 8469:LOC102930068
uniprot id: M7B1R8
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

8469:LOC102940161
gene id: 8469:LOC102940161
uniprot id: M7BJJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8469:USP5
gene id: 8469:USP5
uniprot id: M7B303
names: Similarity
messages: Belongs to the peptidase C19 family.

8469:GSC
gene id: 8469:GSC
uniprot id: M7BFV3
names: Subcellular Location Annotation
messages: Nucleus

8469:LOC102937613
gene id: 8469:LOC102937613
uniprot id: M7AIF0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8469:LOC102934681
gene id: 8469:LOC102934681
uniprot id: M7CJV8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:PANX2
gene id: 8469:PANX2
uniprot id: M7CCQ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: gap junction

8469:BMP2
gene id: 8469:BMP2
uniprot id: M7ARU1
names: Similarity
messages: Belongs to the TGF-beta family.

8469:LOC102930967
gene id: 8469:LOC102930967
uniprot id: M7AS37
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

8469:PEX12
gene id: 8469:PEX12
uniprot id: M7BL32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Peroxisome membrane
messages: Required for protein import into peroxisomes.

8469:SF3B5
gene id: 8469:SF3B5
uniprot id: M7C3U0
names: Similarity
messages: Belongs to the SF3B5 family.

8469:PGAP3
gene id: 8469:PGAP3
uniprot id: M7BE47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Membrane

8469:LOC102936106
gene id: 8469:LOC102936106
uniprot id: M7CHW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8469:LOC102931639
gene id: 8469:LOC102931639
uniprot id: M7B7L3
names: Similarity
messages: Belongs to the actin family.

8469:OLFM3
gene id: 8469:OLFM3
uniprot id: M7BC92
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8469:CAMKK2
gene id: 8469:CAMKK2
uniprot id: M7BGQ2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8469:LOC102947706
gene id: 8469:LOC102947706
uniprot id: M7BHX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8469:PAQR7
gene id: 8469:PAQR7
uniprot id: M7AR91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8469:TBC1D24
gene id: 8469:TBC1D24
uniprot id: M7BS50
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse
messages: Synapse

8469:LOC102932979
gene id: 8469:LOC102932979
uniprot id: M7B0D5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8469:LOC102943008
gene id: 8469:LOC102943008
uniprot id: M7BAZ3
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8469:RPRM
gene id: 8469:RPRM
uniprot id: M7C2Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reprimo family.
messages: Cytoplasm
messages: Membrane

8469:PPIA
gene id: 8469:PPIA
uniprot id: M7BD06
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8469:BTF3L4
gene id: 8469:BTF3L4
uniprot id: M7B6G2
names: Similarity
messages: Belongs to the NAC-beta family.

8469:LOC102937438
gene id: 8469:LOC102937438
uniprot id: M7B106
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

8469:YPEL5
gene id: 8469:YPEL5
uniprot id: M7AHQ3
names: Similarity
messages: Belongs to the yippee family.

8469:LOC102940501
gene id: 8469:LOC102940501
uniprot id: M7BST1
names: Similarity
messages: Belongs to the protein kinase superfamily.

8469:SOX9
gene id: 8469:SOX9
uniprot id: M7C4G4
names: Subcellular Location Annotation
messages: Nucleus

8469:RAD50
gene id: 8469:RAD50
uniprot id: M7B560
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

8469:LOC102936983
gene id: 8469:LOC102936983
uniprot id: M7AU01
names: Similarity
messages: Belongs to the S-100 family.

8469:MED30
gene id: 8469:MED30
uniprot id: M7BND7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8469:LOC102932266
gene id: 8469:LOC102932266
uniprot id: M7BYR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the leptin family.
messages: Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways.
messages: Secreted

8469:TMEM38A
gene id: 8469:TMEM38A
uniprot id: M7AMV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

8469:KPNA2
gene id: 8469:KPNA2
uniprot id: M7CGX6
names: Similarity
messages: Belongs to the importin alpha family.

8469:ITM2B
gene id: 8469:ITM2B
uniprot id: M7BK73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8469:EDNRA
gene id: 8469:EDNRA
uniprot id: M7BP24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

8469:LOC102935505
gene id: 8469:LOC102935505
uniprot id: M7BTR1
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102943316
gene id: 8469:LOC102943316
uniprot id: M7B956
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:NPFFR2
gene id: 8469:NPFFR2
uniprot id: M7B0C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

8469:SLITRK6
gene id: 8469:SLITRK6
uniprot id: M7BHN9
names: Similarity
messages: Belongs to the SLITRK family.

8469:LOC102946526
gene id: 8469:LOC102946526
uniprot id: M7BRJ5
names: Similarity
messages: Belongs to the AKAP110 family.

8469:MID1
gene id: 8469:MID1
uniprot id: M7BTS6
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

8469:LOC102940420
gene id: 8469:LOC102940420
uniprot id: M7C9P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:KCNJ10
gene id: 8469:KCNJ10
uniprot id: M7BPA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8469:BPGM
gene id: 8469:BPGM
uniprot id: M7BAR7
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

8469:NTMT1
gene id: 8469:NTMT1
uniprot id: M7BBZ2
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

8469:LOC102943689
gene id: 8469:LOC102943689
uniprot id: M7BXJ6
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

8469:BANF2
gene id: 8469:BANF2
uniprot id: M7BWX7
names: Subcellular Location Annotation
messages: Nucleus

8469:LOC102938934
gene id: 8469:LOC102938934
uniprot id: M7AVK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: synaptosome

8469:CIAPIN1
gene id: 8469:CIAPIN1
uniprot id: M7BKH3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

8469:LOC102930009
gene id: 8469:LOC102930009
uniprot id: M7BHW7
names: Similarity
messages: Belongs to the globin family.

8469:SOX2
gene id: 8469:SOX2
uniprot id: M7BEU8
names: Subcellular Location Annotation
messages: Nucleus

8469:PTGER4
gene id: 8469:PTGER4
uniprot id: M7BQ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

8469:LOC102945158
gene id: 8469:LOC102945158
uniprot id: M7C7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8469:LOC102942559
gene id: 8469:LOC102942559
uniprot id: M7BDD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8469:TADA2B
gene id: 8469:TADA2B
uniprot id: M7C390
names: Subcellular Location Annotation
messages: Nucleus

8469:NOP14
gene id: 8469:NOP14
uniprot id: M7BC72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

8469:HDHD3
gene id: 8469:HDHD3
uniprot id: M7BTE9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

8469:GPR6
gene id: 8469:GPR6
uniprot id: M7C0Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:RAB39B
gene id: 8469:RAB39B
uniprot id: M7C4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

8469:SLC16A1
gene id: 8469:SLC16A1
uniprot id: M7BJU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

8469:RPS21
gene id: 8469:RPS21
uniprot id: M7C5Q5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

8469:LOC102931375
gene id: 8469:LOC102931375
uniprot id: M7BN63
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Cell membrane
messages: Homodimer.
messages: Membrane

8469:FAXC
gene id: 8469:FAXC
uniprot id: M7ATX9
names: Similarity
messages: Belongs to the FAX family.

8469:MAB21L1
gene id: 8469:MAB21L1
uniprot id: M7AZS1
names: Similarity
messages: Belongs to the mab-21 family.

8469:BPNT1
gene id: 8469:BPNT1
uniprot id: M7B007
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8469:PLK4
gene id: 8469:PLK4
uniprot id: M7BEL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: centriole

8469:LOC102943013
gene id: 8469:LOC102943013
uniprot id: M7AH59
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102941206
gene id: 8469:LOC102941206
uniprot id: M7AUW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:GABRA1
gene id: 8469:GABRA1
uniprot id: M7B914
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8469:ATOH7
gene id: 8469:ATOH7
uniprot id: M7BXK3
names: Subcellular Location Annotation
messages: Nucleus
messages: Perikaryon
messages: axon

8469:LOC102942332
gene id: 8469:LOC102942332
uniprot id: M7AYU6
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

8469:MED7
gene id: 8469:MED7
uniprot id: M7C8X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

8469:MMP2
gene id: 8469:MMP2
uniprot id: M7C9G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: extracellular matrix

8469:REV1
gene id: 8469:REV1
uniprot id: M7BG13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

8469:LPAR2
gene id: 8469:LPAR2
uniprot id: M7B1G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

8469:PRKCD
gene id: 8469:PRKCD
uniprot id: M7C5J4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression.
messages: Cytoplasm
messages: Interacts with PDPK1 (via N-terminal region), RAD9A, CDCP1, MUC1 and VASP.
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: perinuclear region

8469:TEKT5
gene id: 8469:TEKT5
uniprot id: M7C002
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8469:IRF8
gene id: 8469:IRF8
uniprot id: M7C6Q1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8469:LOC102937515
gene id: 8469:LOC102937515
uniprot id: M7BSK4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8469:ZFP36L1
gene id: 8469:ZFP36L1
uniprot id: M7BSU6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8469:GPR132
gene id: 8469:GPR132
uniprot id: M7B7A0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:KIF27
gene id: 8469:KIF27
uniprot id: M7B4H1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8469:GPR17
gene id: 8469:GPR17
uniprot id: M7C338
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:COQ5
gene id: 8469:COQ5
uniprot id: M7B840
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

8469:LRRC8C
gene id: 8469:LRRC8C
uniprot id: M7ARY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8469:LOC102943383
gene id: 8469:LOC102943383
uniprot id: M7ARS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102947618
gene id: 8469:LOC102947618
uniprot id: M7BF37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:KEF27 p03
gene id: 8469:KEF27_p03
uniprot id: Q9XPH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

8469:LOC102934650
gene id: 8469:LOC102934650
uniprot id: M7BBZ5
names: Similarity
messages: Belongs to the PHYHIP family.

8469:THEMIS2
gene id: 8469:THEMIS2
uniprot id: M7BCS1
names: Similarity
messages: Belongs to the themis family.

8469:SERPINF1
gene id: 8469:SERPINF1
uniprot id: M7BIW6
names: Similarity
messages: Belongs to the serpin family.

8469:TBX5
gene id: 8469:TBX5
uniprot id: M7ANR8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8469:GPR15
gene id: 8469:GPR15
uniprot id: M7BDL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102931077
gene id: 8469:LOC102931077
uniprot id: M7C6N4
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

8469:HCN3
gene id: 8469:HCN3
uniprot id: M7BIB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

8469:LOC102938641
gene id: 8469:LOC102938641
uniprot id: M7AZX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102942421
gene id: 8469:LOC102942421
uniprot id: M7BBA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LLPH
gene id: 8469:LLPH
uniprot id: M7B8J1
names: Similarity
messages: Belongs to the learning-associated protein family.

8469:RTN3
gene id: 8469:RTN3
uniprot id: M7AKX7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8469:MRPL32
gene id: 8469:MRPL32
uniprot id: M7C6L3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

8469:LOC102931213
gene id: 8469:LOC102931213
uniprot id: M7BQ80
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

8469:NDUFS8
gene id: 8469:NDUFS8
uniprot id: M7AX85
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

8469:SLC25A51
gene id: 8469:SLC25A51
uniprot id: M7AS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8469:UGDH
gene id: 8469:UGDH
uniprot id: M7B289
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

8469:LOC102944876
gene id: 8469:LOC102944876
uniprot id: M7C8U8
names: Subcellular Location Annotation
messages: Membrane

8469:EXOC3
gene id: 8469:EXOC3
uniprot id: M7C0M7
names: Similarity
messages: Belongs to the SEC6 family.

8469:RCAN3
gene id: 8469:RCAN3
uniprot id: M7ATM1
names: Similarity
messages: Belongs to the RCAN family.

8469:LOC102946303
gene id: 8469:LOC102946303
uniprot id: M7BTE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:KCNF1
gene id: 8469:KCNF1
uniprot id: M7C1F7
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102935708
gene id: 8469:LOC102935708
uniprot id: M7AMV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:MUS81
gene id: 8469:MUS81
uniprot id: M7CEH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

8469:LOC102932975
gene id: 8469:LOC102932975
uniprot id: M7B445
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:NKX6-1
gene id: 8469:NKX6-1
uniprot id: M7B4G5
names: Subcellular Location Annotation
messages: Nucleus

8469:LOC102945028
gene id: 8469:LOC102945028
uniprot id: M7BUS5
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

8469:APOA4
gene id: 8469:APOA4
uniprot id: M7BAX7
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8469:LOC102936293
gene id: 8469:LOC102936293
uniprot id: M7BU08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Interacts with ASTL.
messages: Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.

8469:ARL14
gene id: 8469:ARL14
uniprot id: M7BAW5
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8469:LOC102941576
gene id: 8469:LOC102941576
uniprot id: M7B1G1
names: Similarity
messages: Belongs to the peptidase A1 family.

8469:LOC102942343
gene id: 8469:LOC102942343
uniprot id: M7BC13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPACA4/bouncer family.
messages: Cell membrane
messages: Membrane

8469:LOC102937488
gene id: 8469:LOC102937488
uniprot id: M7BQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

8469:PTGS2
gene id: 8469:PTGS2
uniprot id: M7C2Z8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Microsome membrane

8469:OXSM
gene id: 8469:OXSM
uniprot id: M7B628
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

8469:LOC102947854
gene id: 8469:LOC102947854
uniprot id: M7BBG5
names: Subcellular Location Annotation
messages: Membrane

8469:MMP7
gene id: 8469:MMP7
uniprot id: M7CBA3
names: Similarity
messages: Belongs to the peptidase M10A family.

8469:LOC102932523
gene id: 8469:LOC102932523
uniprot id: M7B8H4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:EXTL2
gene id: 8469:EXTL2
uniprot id: M7BC88
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

8469:LOC102933891
gene id: 8469:LOC102933891
uniprot id: M7B1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:LOC102939363
gene id: 8469:LOC102939363
uniprot id: M7C128
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

8469:LOC102939126
gene id: 8469:LOC102939126
uniprot id: M7C6J5
names: Subcellular Location Annotation
messages: Membrane

8469:LOXL1
gene id: 8469:LOXL1
uniprot id: M7C5A9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8469:AMER2
gene id: 8469:AMER2
uniprot id: M7BWH2
names: Similarity
messages: Belongs to the Amer family.

8469:ECHDC2
gene id: 8469:ECHDC2
uniprot id: M7BZM4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

8469:ADRA2C
gene id: 8469:ADRA2C
uniprot id: M7BTZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102944661
gene id: 8469:LOC102944661
uniprot id: M7BQP4
names: Subcellular Location Annotation
messages: Membrane

8469:HSPB2
gene id: 8469:HSPB2
uniprot id: M7BHM8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8469:PI4KB
gene id: 8469:PI4KB
uniprot id: M7BI93
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8469:HSPA8
gene id: 8469:HSPA8
uniprot id: M7BA41
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8469:LOC102945826
gene id: 8469:LOC102945826
uniprot id: M7AIJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:PIAS4
gene id: 8469:PIAS4
uniprot id: M7AWU9
names: Similarity
messages: Belongs to the PIAS family.

8469:LOC102938880
gene id: 8469:LOC102938880
uniprot id: M7CL63
names: Subcellular Location Annotation
messages: Membrane

8469:KLHL15
gene id: 8469:KLHL15
uniprot id: M7AMA6
names: Subcellular Location Annotation
messages: Nucleus

8469:CCDC124
gene id: 8469:CCDC124
uniprot id: M7AGR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CCDC124 family.
messages: Interacts with RASGEF1B.
messages: Required for proper progression of late cytokinetic stages.

8469:LOC102933126
gene id: 8469:LOC102933126
uniprot id: M7B2B2
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

8469:SLC18A3
gene id: 8469:SLC18A3
uniprot id: M7AVI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

8469:LOC102936122
gene id: 8469:LOC102936122
uniprot id: M7C797
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8469:TSHZ3
gene id: 8469:TSHZ3
uniprot id: M7C8I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

8469:TOMM40L
gene id: 8469:TOMM40L
uniprot id: M7ATD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

8469:LOC102940263
gene id: 8469:LOC102940263
uniprot id: M7ALZ6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8469:MRPL16
gene id: 8469:MRPL16
uniprot id: M7ANF3
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

8469:LOC102933165
gene id: 8469:LOC102933165
uniprot id: M7CAF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:IFITM5
gene id: 8469:IFITM5
uniprot id: M7C2L0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8469:TRIM56
gene id: 8469:TRIM56
uniprot id: M7BQ33
names: Similarity
messages: Belongs to the TRIM/RBCC family.

8469:LOC102947740
gene id: 8469:LOC102947740
uniprot id: M7BP40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

8469:SLC25A4
gene id: 8469:SLC25A4
uniprot id: M7AS88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

8469:FGF3
gene id: 8469:FGF3
uniprot id: M7AS26
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8469:DNAJB12
gene id: 8469:DNAJB12
uniprot id: M7AUV3
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102930900
gene id: 8469:LOC102930900
uniprot id: M7AJY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102929436
gene id: 8469:LOC102929436
uniprot id: M7CKN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:NMUR1
gene id: 8469:NMUR1
uniprot id: M7BCU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

8469:CYSLTR1
gene id: 8469:CYSLTR1
uniprot id: M7BQ16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8469:C7H10orf53
gene id: 8469:C7H10orf53
uniprot id: M7BKL1
names: Similarity
messages: Belongs to the UPF0728 family.

8469:PTP4A1
gene id: 8469:PTP4A1
uniprot id: M7C3G0
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8469:HMOX2
gene id: 8469:HMOX2
uniprot id: M7BMN7
names: Similarity
messages: Belongs to the heme oxygenase family.

8469:LOC102934730
gene id: 8469:LOC102934730
uniprot id: M7AWG6
names: Similarity
messages: Belongs to the CLCR family.

8469:TSPAN3
gene id: 8469:TSPAN3
uniprot id: M7ASW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8469:LOC102937338
gene id: 8469:LOC102937338
uniprot id: M7C6S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

8469:TNFAIP3
gene id: 8469:TNFAIP3
uniprot id: M7C9W3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8469:SIM1
gene id: 8469:SIM1
uniprot id: M7AY07
names: Subcellular Location Annotation
messages: Nucleus

8469:FAM163A
gene id: 8469:FAM163A
uniprot id: M7BFV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

8469:ROMO1
gene id: 8469:ROMO1
uniprot id: M7CJX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

8469:GPRC5A
gene id: 8469:GPRC5A
uniprot id: M7B8L0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8469:LOC102946150
gene id: 8469:LOC102946150
uniprot id: M7BZ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

8469:GATA3
gene id: 8469:GATA3
uniprot id: M7C346
names: Subcellular Location Annotation
messages: Nucleus

8469:LOC102938113
gene id: 8469:LOC102938113
uniprot id: M7B8H4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:LOC102936732
gene id: 8469:LOC102936732
uniprot id: M7B8H4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:LOC102932691
gene id: 8469:LOC102932691
uniprot id: M7ANZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

8469:ATP6V0E1
gene id: 8469:ATP6V0E1
uniprot id: M7BN71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8469:LOC102933747
gene id: 8469:LOC102933747
uniprot id: M7B0F1
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

8469:CALHM1
gene id: 8469:CALHM1
uniprot id: M7CAD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

8469:TRAPPC4
gene id: 8469:TRAPPC4
uniprot id: M7BZ82
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

8469:POU3F4
gene id: 8469:POU3F4
uniprot id: M7BVH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

8469:MRPS33
gene id: 8469:MRPS33
uniprot id: M7AW60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

8469:KCNA1
gene id: 8469:KCNA1
uniprot id: M7C232
names: Subcellular Location Annotation
messages: Membrane

8469:MYMK
gene id: 8469:MYMK
uniprot id: M7BBU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

8469:CCND1
gene id: 8469:CCND1
uniprot id: M7BIT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

8469:GDF5
gene id: 8469:GDF5
uniprot id: M7BVX6
names: Similarity
messages: Belongs to the TGF-beta family.

8469:LOC102935880
gene id: 8469:LOC102935880
uniprot id: M7BRK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8469:LOC102939633
gene id: 8469:LOC102939633
uniprot id: M7BRL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Mitochondrion inner membrane

8469:PROKR1
gene id: 8469:PROKR1
uniprot id: M7BUH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8469:CHRM2
gene id: 8469:CHRM2
uniprot id: M7AMS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8469:GRN
gene id: 8469:GRN
uniprot id: M7BW30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8469:LOC102937150
gene id: 8469:LOC102937150
uniprot id: M7AK91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:PTER
gene id: 8469:PTER
uniprot id: M7BGE1
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8469:PAQR8
gene id: 8469:PAQR8
uniprot id: M7BEM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8469:LOC102934462
gene id: 8469:LOC102934462
uniprot id: M7BP44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with VGF-derived peptide TLQP-21.
messages: Membrane
messages: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

8469:LOC102936691
gene id: 8469:LOC102936691
uniprot id: M7AIM3
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102944079
gene id: 8469:LOC102944079
uniprot id: M7B8U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space

8469:LOC102939725
gene id: 8469:LOC102939725
uniprot id: M7C5E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

8469:SRC
gene id: 8469:SRC
uniprot id: M7BRB1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8469:LOC102933768
gene id: 8469:LOC102933768
uniprot id: M7C9L0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:UCN3
gene id: 8469:UCN3
uniprot id: M7CF02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

8469:LOC102947858
gene id: 8469:LOC102947858
uniprot id: M7AKC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102948124
gene id: 8469:LOC102948124
uniprot id: M7BEY6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8469:LRRC8A
gene id: 8469:LRRC8A
uniprot id: M7C2Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8469:LOC102939909
gene id: 8469:LOC102939909
uniprot id: M7B5X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:KEF27 p06
gene id: 8469:KEF27_p06
uniprot id: Q9XPH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

8469:KEF27 p01
gene id: 8469:KEF27_p01
uniprot id: I1TF54
uniprot id: Q9TEC1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme b groups non-covalently.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The cytochrome bc1 complex contains 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and probably 6 low-molecular weight proteins.
messages: The full-length protein contains only eight transmembrane helices, not nine as predicted by bioinformatics tools.

8469:PPIL1
gene id: 8469:PPIL1
uniprot id: M7ASJ3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8469:POP5
gene id: 8469:POP5
uniprot id: M7BQ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

8469:MAPKAP1
gene id: 8469:MAPKAP1
uniprot id: M7BR50
names: Similarity
messages: Belongs to the SIN1 family.

8469:RAD9A
gene id: 8469:RAD9A
uniprot id: M7C007
names: Similarity
messages: Belongs to the rad9 family.

8469:ACAN
gene id: 8469:ACAN
uniprot id: M7BB88
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8469:UTP15
gene id: 8469:UTP15
uniprot id: M7B0Q1
names: Subcellular Location Annotation
messages: nucleolus

8469:JUNB
gene id: 8469:JUNB
uniprot id: M7BH56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8469:NEFM
gene id: 8469:NEFM
uniprot id: M7B4P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: axon
messages: cytoskeleton

8469:FAM72A
gene id: 8469:FAM72A
uniprot id: M7BFH3
names: Similarity
messages: Belongs to the FAM72 family.

8469:LOC102941751
gene id: 8469:LOC102941751
uniprot id: M7BDU5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:LOC102946817
gene id: 8469:LOC102946817
uniprot id: M7ALX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8469:FAM167A
gene id: 8469:FAM167A
uniprot id: M7B4Z8
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

8469:MB
gene id: 8469:MB
uniprot id: P02202
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

8469:EGR3
gene id: 8469:EGR3
uniprot id: M7AXJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

8469:GOT1L1
gene id: 8469:GOT1L1
uniprot id: M7CAN1
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

8469:NKX2-8
gene id: 8469:NKX2-8
uniprot id: M7BRH1
names: Subcellular Location Annotation
messages: Nucleus

8469:NEUROD6
gene id: 8469:NEUROD6
uniprot id: M7CBT5
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8469:LOC102945154
gene id: 8469:LOC102945154
uniprot id: M7C9G0
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8469:BAAT
gene id: 8469:BAAT
uniprot id: M7B361
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8469:LOC102940735
gene id: 8469:LOC102940735
uniprot id: M7BQK4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:SLC35A3
gene id: 8469:SLC35A3
uniprot id: M7BC79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

8469:LOC102929967
gene id: 8469:LOC102929967
uniprot id: M7BPQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8469:KCNJ1
gene id: 8469:KCNJ1
uniprot id: M7BBS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8469:LIPT1
gene id: 8469:LIPT1
uniprot id: M7B4W3
names: Similarity
messages: Belongs to the LplA family.

8469:CMKLR2
gene id: 8469:CMKLR2
uniprot id: M7AIZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

8469:RAB27B
gene id: 8469:RAB27B
uniprot id: M7CGG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

8469:ASRGL1
gene id: 8469:ASRGL1
uniprot id: M7AM86
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8469:SYS1
gene id: 8469:SYS1
uniprot id: M7BRB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

8469:MFSD5
gene id: 8469:MFSD5
uniprot id: M7C8P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

8469:WARS1
gene id: 8469:WARS1
uniprot id: M7B632
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8469:C12H16orf87
gene id: 8469:C12H16orf87
uniprot id: M7C5X1
names: Similarity
messages: Belongs to the UPF0547 family.

8469:FDXR
gene id: 8469:FDXR
uniprot id: M7B1I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion
messages: Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

8469:LOC102934871
gene id: 8469:LOC102934871
uniprot id: M7AYI3
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8469:TM9SF4
gene id: 8469:TM9SF4
uniprot id: M7B5L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

8469:C9H3orf70
gene id: 8469:C9H3orf70
uniprot id: M7BZK4
names: Similarity
messages: Belongs to the UPF0524 family.

8469:LOC102946747
gene id: 8469:LOC102946747
uniprot id: M7CAG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:JUN
gene id: 8469:JUN
uniprot id: M7C7E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8469:RPL32
gene id: 8469:RPL32
uniprot id: M7BIT1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

8469:EVX2
gene id: 8469:EVX2
uniprot id: M7C3Q6
names: Subcellular Location Annotation
messages: Nucleus

8469:FAM83H
gene id: 8469:FAM83H
uniprot id: M7BF87
names: Similarity
messages: Belongs to the FAM83 family.

8469:LOC102937429
gene id: 8469:LOC102937429
uniprot id: M7BS38
names: Function
names: Similarity
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.

8469:OIP5
gene id: 8469:OIP5
uniprot id: M7C560
names: Function
names: Subcellular Location Annotation
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

8469:SMC4
gene id: 8469:SMC4
uniprot id: M7B6H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Chromosome
messages: Nucleus

8469:PSMC1
gene id: 8469:PSMC1
uniprot id: M7C5Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

8469:LOC102947135
gene id: 8469:LOC102947135
uniprot id: M7BNL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:RPL9
gene id: 8469:RPL9
uniprot id: M7BMZ3
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

8469:BANF1
gene id: 8469:BANF1
uniprot id: M7CEG4
names: Subcellular Location Annotation
messages: Nucleus

8469:IP6K1
gene id: 8469:IP6K1
uniprot id: M7BEH1
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8469:MAB21L2
gene id: 8469:MAB21L2
uniprot id: M7BR04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mab-21 family.
messages: Cytoplasm
messages: Nucleus

8469:ORMDL1
gene id: 8469:ORMDL1
uniprot id: M7ANX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

8469:GABRB2
gene id: 8469:GABRB2
uniprot id: M7APL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8469:LOC102944349
gene id: 8469:LOC102944349
uniprot id: M7AI21
names: Similarity
messages: Belongs to the ATG8 family.

8469:TOR4A
gene id: 8469:TOR4A
uniprot id: M7BC07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Membrane

8469:LOC102936995
gene id: 8469:LOC102936995
uniprot id: M7B272
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8469:KEF27 p07
gene id: 8469:KEF27_p07
uniprot id: Q9XPI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

8469:DYM
gene id: 8469:DYM
uniprot id: M7BSE7
names: Similarity
messages: Belongs to the dymeclin family.

8469:LOC102932695
gene id: 8469:LOC102932695
uniprot id: M7ATM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

8469:LOC102933214
gene id: 8469:LOC102933214
uniprot id: M7BJ51
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:LOC102943365
gene id: 8469:LOC102943365
uniprot id: M7BBD0
names: Subcellular Location Annotation
messages: Nucleus

8469:AGT
gene id: 8469:AGT
uniprot id: M7BA81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

8469:SERP1
gene id: 8469:SERP1
uniprot id: M7C0W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

8469:CCT7
gene id: 8469:CCT7
uniprot id: M7CHI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

8469:HOXB6
gene id: 8469:HOXB6
uniprot id: M7C083
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8469:LOC102933196
gene id: 8469:LOC102933196
uniprot id: M7B1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:RAB9B
gene id: 8469:RAB9B
uniprot id: M7B8V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

8469:HSPD1
gene id: 8469:HSPD1
uniprot id: M7B7Y4
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

8469:LOC102936902
gene id: 8469:LOC102936902
uniprot id: M7B3E7
names: Similarity
messages: Belongs to the serpin family.

8469:SAT1
gene id: 8469:SAT1
uniprot id: M7B0P7
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

8469:LOC102929605
gene id: 8469:LOC102929605
uniprot id: M7BQM3
names: Similarity
messages: Belongs to the peptidase M14 family.

8469:LOC102935717
gene id: 8469:LOC102935717
uniprot id: M7BAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:FGF23
gene id: 8469:FGF23
uniprot id: M7BKM4
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8469:HARBI1
gene id: 8469:HARBI1
uniprot id: M7AMF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

8469:PCSK9
gene id: 8469:PCSK9
uniprot id: M7BNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell surface
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Endosome
messages: Golgi apparatus
messages: Lysosome

8469:PACC1
gene id: 8469:PACC1
uniprot id: M7BP04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

8469:LOC102946801
gene id: 8469:LOC102946801
uniprot id: M7AU85
names: Similarity
messages: Belongs to the cytochrome P450 family.

8469:HTR1D
gene id: 8469:HTR1D
uniprot id: M7AYW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:TOMM40
gene id: 8469:TOMM40
uniprot id: M7AZN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

8469:CDC20
gene id: 8469:CDC20
uniprot id: M7C196
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

8469:ATP6V0D2
gene id: 8469:ATP6V0D2
uniprot id: M7CC51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8469:LOC102947793
gene id: 8469:LOC102947793
uniprot id: M7BB13
names: Subcellular Location Annotation
messages: Membrane

8469:CLRN1
gene id: 8469:CLRN1
uniprot id: M7BJA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

8469:FAM167B
gene id: 8469:FAM167B
uniprot id: M7B8D3
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

8469:LOC102930467
gene id: 8469:LOC102930467
uniprot id: M7AGJ0
names: Subcellular Location Annotation
messages: Membrane

8469:GJA3
gene id: 8469:GJA3
uniprot id: M7BWJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8469:NMUR2
gene id: 8469:NMUR2
uniprot id: M7AY70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

8469:MPEG1
gene id: 8469:MPEG1
uniprot id: M7BHF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

8469:BLOC1S3
gene id: 8469:BLOC1S3
uniprot id: M7ANP5
names: Similarity
messages: Belongs to the BLOC1S3 family.

8469:LOC102937397
gene id: 8469:LOC102937397
uniprot id: M7C8B6
names: Similarity
messages: Belongs to the profilin family.

8469:KEF27 p02
gene id: 8469:KEF27_p02
uniprot id: Q9XPH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

8469:SIX4
gene id: 8469:SIX4
uniprot id: M7BRA0
names: Subcellular Location Annotation
messages: Nucleus

8469:PNMT
gene id: 8469:PNMT
uniprot id: M7B9L9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

8469:CHST12
gene id: 8469:CHST12
uniprot id: M7BR55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8469:LOC102936750
gene id: 8469:LOC102936750
uniprot id: M7AYK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus

8469:VDAC1
gene id: 8469:VDAC1
uniprot id: M7BUS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

8469:CLDN23
gene id: 8469:CLDN23
uniprot id: M7B4V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8469:MTFP1
gene id: 8469:MTFP1
uniprot id: M7BH64
names: Similarity
messages: Belongs to the MTFP1 family.

8469:LOC102940144
gene id: 8469:LOC102940144
uniprot id: M7BWG1
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

8469:LOC102938714
gene id: 8469:LOC102938714
uniprot id: M7AUM6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8469:PLA2G2F
gene id: 8469:PLA2G2F
uniprot id: M7B849
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

8469:CCKAR
gene id: 8469:CCKAR
uniprot id: M7BZ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

8469:EVX1
gene id: 8469:EVX1
uniprot id: M7C093
names: Subcellular Location Annotation
messages: Nucleus

8469:LOC102936260
gene id: 8469:LOC102936260
uniprot id: M7BSC9
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8469:B3GNT2
gene id: 8469:B3GNT2
uniprot id: M7BXX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8469:IRAK4
gene id: 8469:IRAK4
uniprot id: M7B485
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

8469:SAP30
gene id: 8469:SAP30
uniprot id: M7AU45
names: Similarity
messages: Belongs to the SAP30 family.

8469:NR1H3
gene id: 8469:NR1H3
uniprot id: M7CJ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8469:UNC50
gene id: 8469:UNC50
uniprot id: M7AVV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

8469:HEBP1
gene id: 8469:HEBP1
uniprot id: M7B1Y6
names: Similarity
messages: Belongs to the HEBP family.

8469:DUSP10
gene id: 8469:DUSP10
uniprot id: M7BSP6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8469:HOXB8
gene id: 8469:HOXB8
uniprot id: M7BDV5
names: Subcellular Location Annotation
messages: Nucleus

8469:LOC102941819
gene id: 8469:LOC102941819
uniprot id: M7ANN5
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

8469:LOC102945022
gene id: 8469:LOC102945022
uniprot id: M7BWC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

8469:TAF5L
gene id: 8469:TAF5L
uniprot id: M7BA75
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

8469:GNA15
gene id: 8469:GNA15
uniprot id: M7B7E8
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8469:LOC102941371
gene id: 8469:LOC102941371
uniprot id: M7AHQ9
names: Subcellular Location Annotation
messages: Membrane

8469:NR4A3
gene id: 8469:NR4A3
uniprot id: M7BED2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8469:GUCY2C
gene id: 8469:GUCY2C
uniprot id: M7BUS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8469:LOC102943045
gene id: 8469:LOC102943045
uniprot id: M7BHH1
names: Similarity
messages: Belongs to the serpin family.

8469:GJC1
gene id: 8469:GJC1
uniprot id: M7BUB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8469:TRIAP1
gene id: 8469:TRIAP1
uniprot id: M7BQ28
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

8469:LOC102936523
gene id: 8469:LOC102936523
uniprot id: M7AZE6
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

8469:LOC102939173
gene id: 8469:LOC102939173
uniprot id: M7AK85
names: Similarity
messages: Belongs to the globin family.

8469:LOC102939002
gene id: 8469:LOC102939002
uniprot id: M7AU66
names: Similarity
messages: Belongs to the ARTD/PARP family.

8469:LOC102944825
gene id: 8469:LOC102944825
uniprot id: M7BX64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8469:PCMTD2
gene id: 8469:PCMTD2
uniprot id: M7BJI1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

8469:TLX1
gene id: 8469:TLX1
uniprot id: M7BAB6
names: Subcellular Location Annotation
messages: Nucleus

8469:LOC102934959
gene id: 8469:LOC102934959
uniprot id: M7BDX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102942364
gene id: 8469:LOC102942364
uniprot id: M7C7B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102941152
gene id: 8469:LOC102941152
uniprot id: M7BX16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

8469:LOC102933481
gene id: 8469:LOC102933481
uniprot id: M7BRN8
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102946276
gene id: 8469:LOC102946276
uniprot id: M7AK89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102945222
gene id: 8469:LOC102945222
uniprot id: M7ATN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:TICAM1
gene id: 8469:TICAM1
uniprot id: M7ANB3
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer. Found in a multi-helicase-TICAM1 complex at least composed of DHX36, DDX1, DDX21 and TICAM1.
messages: Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Phosphorylation by TBK1 on the pLxIS motif leads to recruitment and subsequent activation of the transcription factor IRF3 to induce expression of type I interferon and exert a potent immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of pro-inflammatory cytokines.
messages: Mitochondrion
messages: The N-terminal region is essential for activation of the IFNB promoter activity.
messages: autophagosome
messages: cytosol

8469:CNOT6L
gene id: 8469:CNOT6L
uniprot id: M7BBE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

8469:LRRC8D
gene id: 8469:LRRC8D
uniprot id: M7AWH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8469:B3GALT2
gene id: 8469:B3GALT2
uniprot id: M7B6V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8469:LOC102937354
gene id: 8469:LOC102937354
uniprot id: M7BZS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:DNAAF4
gene id: 8469:DNAAF4
uniprot id: M7BNZ3
names: Subcellular Location Annotation
messages: Dynein axonemal particle
messages: neuron projection

8469:LOC102945987
gene id: 8469:LOC102945987
uniprot id: M7BAP2
names: Similarity
messages: Belongs to the cytochrome P450 family.

8469:ANAPC16
gene id: 8469:ANAPC16
uniprot id: M7BAQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

8469:SMC1B
gene id: 8469:SMC1B
uniprot id: M7B9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

8469:SLC52A2
gene id: 8469:SLC52A2
uniprot id: M7B4Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

8469:SULT2A1
gene id: 8469:SULT2A1
uniprot id: M7CCR4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8469:LOC102942943
gene id: 8469:LOC102942943
uniprot id: M7BZH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8469:SPC25
gene id: 8469:SPC25
uniprot id: M7BLC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

8469:NDUFV3
gene id: 8469:NDUFV3
uniprot id: M7B305
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

8469:NUDT1
gene id: 8469:NUDT1
uniprot id: M7AYH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

8469:AOC3
gene id: 8469:AOC3
uniprot id: M7BXH1
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

8469:PTGIR
gene id: 8469:PTGIR
uniprot id: M7AR29
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:LOC102939824
gene id: 8469:LOC102939824
uniprot id: M7AYC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:MANEAL
gene id: 8469:MANEAL
uniprot id: M7BGY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

8469:UBN1
gene id: 8469:UBN1
uniprot id: M7BUP3
names: Similarity
messages: Belongs to the ubinuclein family.

8469:SEC22B
gene id: 8469:SEC22B
uniprot id: M7BG16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8469:RNF2
gene id: 8469:RNF2
uniprot id: M7BNJ5
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm

8469:LOC102937887
gene id: 8469:LOC102937887
uniprot id: M7B445
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:TTC30B
gene id: 8469:TTC30B
uniprot id: M7BHG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

8469:LOC102934820
gene id: 8469:LOC102934820
uniprot id: M7CHQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102946733
gene id: 8469:LOC102946733
uniprot id: M7B0F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:BABAM1
gene id: 8469:BABAM1
uniprot id: M7AN18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BABAM1 family.
messages: Nucleus

8469:KCNK16
gene id: 8469:KCNK16
uniprot id: M7B8B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8469:NME3
gene id: 8469:NME3
uniprot id: M7BU52
names: Similarity
messages: Belongs to the NDK family.

8469:LOC102946506
gene id: 8469:LOC102946506
uniprot id: M7AII8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102944489
gene id: 8469:LOC102944489
uniprot id: M7BZH9
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8469:ENPP6
gene id: 8469:ENPP6
uniprot id: M7BYE4
names: Similarity
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

8469:LOC102932068
gene id: 8469:LOC102932068
uniprot id: M7B6Y2
names: Similarity
messages: Belongs to the NSG family.

8469:LOC102948310
gene id: 8469:LOC102948310
uniprot id: M7AWS0
names: Similarity
messages: Belongs to the peptidase C1 family.

8469:RO60
gene id: 8469:RO60
uniprot id: M7BXL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

8469:GJA5
gene id: 8469:GJA5
uniprot id: M7BRT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8469:LOC102947297
gene id: 8469:LOC102947297
uniprot id: M7BZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

8469:LOC102944426
gene id: 8469:LOC102944426
uniprot id: M7C8V0
names: Subcellular Location Annotation
messages: Membrane

8469:GJA1
gene id: 8469:GJA1
uniprot id: M7B2W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8469:DGKE
gene id: 8469:DGKE
uniprot id: M7CH06
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8469:HTR1B
gene id: 8469:HTR1B
uniprot id: M7BMX8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1D.
messages: Membrane

8469:APOLD1
gene id: 8469:APOLD1
uniprot id: M7BIJ9
names: Similarity
messages: Belongs to the apolipoprotein L family.

8469:LOC102940196
gene id: 8469:LOC102940196
uniprot id: M7BII1
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:EIF5A2
gene id: 8469:EIF5A2
uniprot id: M7BPJ4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

8469:PIGU
gene id: 8469:PIGU
uniprot id: M7BR70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

8469:AGTR1
gene id: 8469:AGTR1
uniprot id: M7CBE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

8469:LOC102946292
gene id: 8469:LOC102946292
uniprot id: M7BU91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:DPM3
gene id: 8469:DPM3
uniprot id: M7AYP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

8469:DLX2
gene id: 8469:DLX2
uniprot id: M7C2N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8469:NEU2
gene id: 8469:NEU2
uniprot id: M7CD20
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8469:LOC102938962
gene id: 8469:LOC102938962
uniprot id: M7C4W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8469:VMA21
gene id: 8469:VMA21
uniprot id: M7BTH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

8469:HOXB5
gene id: 8469:HOXB5
uniprot id: M7BP48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8469:NSG2
gene id: 8469:NSG2
uniprot id: M7AW14
names: Similarity
messages: Belongs to the NSG family.

8469:ACTC1
gene id: 8469:ACTC1
uniprot id: I6ZP58
names: Similarity
messages: Belongs to the actin family.

8469:LOC102936206
gene id: 8469:LOC102936206
uniprot id: M7BEG8
names: Similarity
messages: Belongs to the CAND family.

8469:NKIRAS2
gene id: 8469:NKIRAS2
uniprot id: M7CHT7
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

8469:LOC102944769
gene id: 8469:LOC102944769
uniprot id: M7B1S8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8469:SPSB1
gene id: 8469:SPSB1
uniprot id: M7BWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

8469:LOC102946634
gene id: 8469:LOC102946634
uniprot id: M7B9S8
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8469:DDX59
gene id: 8469:DDX59
uniprot id: M7CGM7
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

8469:ERMN
gene id: 8469:ERMN
uniprot id: M7BNE5
names: Function
names: Subunit
messages: Binds actin.
messages: Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

8469:GNG3
gene id: 8469:GNG3
uniprot id: M7C281
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8469:GPHB5
gene id: 8469:GPHB5
uniprot id: M7ATP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

8469:HOXD9
gene id: 8469:HOXD9
uniprot id: M7BSL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8469:GRPR
gene id: 8469:GRPR
uniprot id: M7B0U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:FAM83A
gene id: 8469:FAM83A
uniprot id: M7BAV4
names: Similarity
messages: Belongs to the FAM83 family.

8469:GNG8
gene id: 8469:GNG8
uniprot id: M7B4L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8469:DOHH
gene id: 8469:DOHH
uniprot id: M7ANI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

8469:LOC102946426
gene id: 8469:LOC102946426
uniprot id: A0A8K0YBH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

8469:LOC102944779
gene id: 8469:LOC102944779
uniprot id: M7ARB5
names: Subcellular Location Annotation
messages: Membrane

8469:GJD3
gene id: 8469:GJD3
uniprot id: M7B9N8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

8469:LOC102933128
gene id: 8469:LOC102933128
uniprot id: M7B1W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:TECR
gene id: 8469:TECR
uniprot id: M7BFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8469:SLITRK2
gene id: 8469:SLITRK2
uniprot id: M7BDY4
names: Similarity
messages: Belongs to the SLITRK family.

8469:LBX1
gene id: 8469:LBX1
uniprot id: M7AWH6
names: Subcellular Location Annotation
messages: Nucleus

8469:LPAR3
gene id: 8469:LPAR3
uniprot id: M7BGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:CSNK1E
gene id: 8469:CSNK1E
uniprot id: M7AVG9
names: Similarity
messages: Belongs to the protein kinase superfamily.

8469:CSRNP2
gene id: 8469:CSRNP2
uniprot id: M7AU75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8469:COG7
gene id: 8469:COG7
uniprot id: M7BMJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

8469:DDIT4
gene id: 8469:DDIT4
uniprot id: M7BM03
names: Similarity
messages: Belongs to the DDIT4 family.

8469:TAF12
gene id: 8469:TAF12
uniprot id: M7BG91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

8469:PDE6D
gene id: 8469:PDE6D
uniprot id: M7AT11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PDE6D/unc-119 family.
messages: Cytoplasmic vesicle membrane
messages: Interacts with the prenylated catalytic subunits of PDE6, an oligomer composed of two catalytic chains and two inhibitory chains; has no effect on enzyme activity but promotes the release of the prenylated enzyme from cell membrane.
messages: Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
messages: cilium basal body
messages: cytosol

8469:LOC102931653
gene id: 8469:LOC102931653
uniprot id: M7AMF6
names: Subcellular Location Annotation
messages: Membrane

8469:CLDN2
gene id: 8469:CLDN2
uniprot id: M7B8W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8469:SLC25A32
gene id: 8469:SLC25A32
uniprot id: M7BU03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8469:BEST1
gene id: 8469:BEST1
uniprot id: M7BJ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Membrane

8469:ARL9
gene id: 8469:ARL9
uniprot id: M7AKA6
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8469:LOC102934343
gene id: 8469:LOC102934343
uniprot id: M7B8H4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:PLAGL2
gene id: 8469:PLAGL2
uniprot id: M7BCC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

8469:KEF27 p09
gene id: 8469:KEF27_p09
uniprot id: I1TEK0
uniprot id: Q9XPI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase protein 8 family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity).
messages: Mitochondrion membrane

8469:LOC102929386
gene id: 8469:LOC102929386
uniprot id: M7BZS7
names: Similarity
messages: Belongs to the folate receptor family.

8469:PIM3
gene id: 8469:PIM3
uniprot id: M7CI74
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8469:CBY2
gene id: 8469:CBY2
uniprot id: M7BHS7
names: Similarity
messages: Belongs to the chibby family. SPERT subfamily.

8469:LOC102939477
gene id: 8469:LOC102939477
uniprot id: M7AXC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:KCNE2
gene id: 8469:KCNE2
uniprot id: M7BJS7
names: Similarity
messages: Belongs to the potassium channel KCNE family.

8469:CRYAA
gene id: 8469:CRYAA
uniprot id: M7BHB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Contributes to the transparency and refractive index of the lens. May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Cytoplasm

8469:CYP1A
gene id: 8469:CYP1A
uniprot id: T1NXJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8469:LOC102943211
gene id: 8469:LOC102943211
uniprot id: M7BUM1
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102935533
gene id: 8469:LOC102935533
uniprot id: M7BCL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8469:LOC102945281
gene id: 8469:LOC102945281
uniprot id: M7BGS8
names: Similarity
messages: Belongs to the arrestin family.

8469:LOC102940094
gene id: 8469:LOC102940094
uniprot id: M7BHY1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:HOXA2
gene id: 8469:HOXA2
uniprot id: M7BWH8
names: Subcellular Location Annotation
messages: Nucleus

8469:B4GALT4
gene id: 8469:B4GALT4
uniprot id: M7B6Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8469:PARK7
gene id: 8469:PARK7
uniprot id: M7BT43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

8469:CAP1
gene id: 8469:CAP1
uniprot id: M7AZ98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.
messages: Homodimer. Binds actin monomers.
messages: Membrane

8469:DENND11
gene id: 8469:DENND11
uniprot id: M7B6V4
names: Similarity
messages: Belongs to the DENND11 family.

8469:LOC102945594
gene id: 8469:LOC102945594
uniprot id: M7ARS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:NUMB
gene id: 8469:NUMB
uniprot id: M7BNS8
names: Function
messages: Plays a role in the process of neurogenesis.

8469:LOC102934529
gene id: 8469:LOC102934529
uniprot id: M7BXB5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

8469:RIOX1
gene id: 8469:RIOX1
uniprot id: M7CFB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. NO66 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
messages: nucleolus

8469:TMEM151A
gene id: 8469:TMEM151A
uniprot id: M7C485
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

8469:LOC102932035
gene id: 8469:LOC102932035
uniprot id: M7AFU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

8469:SYNDIG1L
gene id: 8469:SYNDIG1L
uniprot id: M7B0Z3
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8469:LOC102938078
gene id: 8469:LOC102938078
uniprot id: M7CJR8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:UTS2
gene id: 8469:UTS2
uniprot id: M7BBE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

8469:AP5M1
gene id: 8469:AP5M1
uniprot id: M7AU46
names: Subcellular Location Annotation
names: Subunit
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

8469:LOC102941327
gene id: 8469:LOC102941327
uniprot id: M7C535
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

8469:S1PR5
gene id: 8469:S1PR5
uniprot id: M7BQM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8469:DCLRE1B
gene id: 8469:DCLRE1B
uniprot id: M7BJU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

8469:ASB8
gene id: 8469:ASB8
uniprot id: M7C8P1
names: Function
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

8469:PPM1B
gene id: 8469:PPM1B
uniprot id: M7BZE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8469:KEF27 p05
gene id: 8469:KEF27_p05
uniprot id: Q9XPH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

8469:LOC102934085
gene id: 8469:LOC102934085
uniprot id: M7CL23
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

8469:LOC102946091
gene id: 8469:LOC102946091
uniprot id: M7BUH2
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102943760
gene id: 8469:LOC102943760
uniprot id: M7BQS7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8469:ADORA2A
gene id: 8469:ADORA2A
uniprot id: M7B2M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

8469:LOC102934728
gene id: 8469:LOC102934728
uniprot id: M7AX76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:RNF152
gene id: 8469:RNF152
uniprot id: M7BAS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

8469:TP53I11
gene id: 8469:TP53I11
uniprot id: M7BCP1
names: Subcellular Location Annotation
messages: Membrane

8469:DRD1
gene id: 8469:DRD1
uniprot id: M7CIT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:SH3BP4
gene id: 8469:SH3BP4
uniprot id: M7BRW7
names: Subcellular Location Annotation
messages: Nucleus
messages: Vesicle
messages: clathrin-coated pit
messages: clathrin-coated vesicle

8469:LOC102930020
gene id: 8469:LOC102930020
uniprot id: M7ALS0
names: Subcellular Location Annotation
messages: Membrane

8469:NPBWR2
gene id: 8469:NPBWR2
uniprot id: M7AZW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:GADD45GIP1
gene id: 8469:GADD45GIP1
uniprot id: M7BYT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
messages: Belongs to the mitochondrion-specific ribosomal protein mL64 family.
messages: Mitochondrion
messages: Nucleus

8469:NPTX2
gene id: 8469:NPTX2
uniprot id: M7BR88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8469:FGF19
gene id: 8469:FGF19
uniprot id: M7ATV2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8469:ATP6V1A
gene id: 8469:ATP6V1A
uniprot id: M7AS54
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

8469:SLC16A8
gene id: 8469:SLC16A8
uniprot id: M7AVH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8469:FOXI1
gene id: 8469:FOXI1
uniprot id: M7AYA2
names: Subcellular Location Annotation
messages: Nucleus

8469:HSD17B10
gene id: 8469:HSD17B10
uniprot id: M7AQR3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8469:CDC42EP3
gene id: 8469:CDC42EP3
uniprot id: M7BP33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8469:AVPR1B
gene id: 8469:AVPR1B
uniprot id: M7B1C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8469:GPX8
gene id: 8469:GPX8
uniprot id: M7CJZ8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

8469:LOC102945916
gene id: 8469:LOC102945916
uniprot id: M7AH44
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:LOC102932028
gene id: 8469:LOC102932028
uniprot id: M7B019
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:ATG101
gene id: 8469:ATG101
uniprot id: M7B6S0
names: Similarity
messages: Belongs to the ATG101 family.

8469:F3
gene id: 8469:F3
uniprot id: M7BFE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

8469:HPDL
gene id: 8469:HPDL
uniprot id: M7B7Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

8469:HHATL
gene id: 8469:HHATL
uniprot id: M7BRH0
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102929521
gene id: 8469:LOC102929521
uniprot id: M7BUU7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8469:LOC102945833
gene id: 8469:LOC102945833
uniprot id: M7BY27
names: Subcellular Location Annotation
messages: Membrane

8469:SEC61G
gene id: 8469:SEC61G
uniprot id: M7C6K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8469:LOC102939259
gene id: 8469:LOC102939259
uniprot id: M7AMI7
names: Subcellular Location Annotation
messages: Membrane

8469:PHKG2
gene id: 8469:PHKG2
uniprot id: M7APG3
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

8469:HPCAL4
gene id: 8469:HPCAL4
uniprot id: M7AZ95
names: Function
messages: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.

8469:CPSF7
gene id: 8469:CPSF7
uniprot id: M7BDN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

8469:PFN3
gene id: 8469:PFN3
uniprot id: M7B001
names: Similarity
messages: Belongs to the profilin family.

8469:GPR68
gene id: 8469:GPR68
uniprot id: M7C5X8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:LOC102935830
gene id: 8469:LOC102935830
uniprot id: M7B8I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8469:LOC102930479
gene id: 8469:LOC102930479
uniprot id: M7C5S5
names: Subcellular Location Annotation
messages: Membrane

8469:NOP10
gene id: 8469:NOP10
uniprot id: M7AMH7
names: Similarity
messages: Belongs to the NOP10 family.

8469:LOC102934496
gene id: 8469:LOC102934496
uniprot id: M7BPV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:LOC102933968
gene id: 8469:LOC102933968
uniprot id: M7BS84
names: Similarity
messages: Belongs to the serpin family.

8469:KCNS2
gene id: 8469:KCNS2
uniprot id: M7BNB4
names: Subcellular Location Annotation
messages: Membrane

8469:TIMP3
gene id: 8469:TIMP3
uniprot id: M7B7Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: extracellular matrix

8469:ELOVL6
gene id: 8469:ELOVL6
uniprot id: M7C889
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

8469:TXNL4B
gene id: 8469:TXNL4B
uniprot id: M7BAA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

8469:STAT3
gene id: 8469:STAT3
uniprot id: M7CHU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8469:SOD3
gene id: 8469:SOD3
uniprot id: M7BHM5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

8469:LOC102933782
gene id: 8469:LOC102933782
uniprot id: M7BZP3
names: Subcellular Location Annotation
messages: Nucleus

8469:MOS
gene id: 8469:MOS
uniprot id: M7BS95
names: Similarity
messages: Belongs to the protein kinase superfamily.

8469:JAGN1
gene id: 8469:JAGN1
uniprot id: M7BD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8469:LOC102929363
gene id: 8469:LOC102929363
uniprot id: M7ARE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:ATP5PF
gene id: 8469:ATP5PF
uniprot id: M7ALV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

8469:VPS26B
gene id: 8469:VPS26B
uniprot id: M7AUE4
names: Similarity
messages: Belongs to the VPS26 family.

8469:LOC102937938
gene id: 8469:LOC102937938
uniprot id: M7BPU6
names: Subcellular Location Annotation
messages: Membrane

8469:PRPH2
gene id: 8469:PRPH2
uniprot id: M7BP28
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

8469:LOC102931132
gene id: 8469:LOC102931132
uniprot id: M7CCB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:C3H6orf120
gene id: 8469:C3H6orf120
uniprot id: M7AZC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: Secreted

8469:LOC102945449
gene id: 8469:LOC102945449
uniprot id: M7ATF6
names: Subcellular Location Annotation
messages: Membrane

8469:TSSC4
gene id: 8469:TSSC4
uniprot id: M7B4L8
names: Similarity
messages: Belongs to the TSSC4 family.

8469:HS3ST1
gene id: 8469:HS3ST1
uniprot id: M7B4P3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8469:ST3GAL1
gene id: 8469:ST3GAL1
uniprot id: M7AVV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8469:LOC102933381
gene id: 8469:LOC102933381
uniprot id: M7B956
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:GATA2
gene id: 8469:GATA2
uniprot id: M7BEL6
names: Subcellular Location Annotation
messages: Nucleus

8469:BRINP2
gene id: 8469:BRINP2
uniprot id: M7BQY4
names: Similarity
messages: Belongs to the BRINP family.

8469:LOC102932532
gene id: 8469:LOC102932532
uniprot id: M7AZJ4
names: Similarity
messages: Belongs to the actin family.

8469:ATAD1
gene id: 8469:ATAD1
uniprot id: M7AHZ3
names: Similarity
messages: Belongs to the AAA ATPase family.

8469:CCNJ
gene id: 8469:CCNJ
uniprot id: M7CBR5
names: Similarity
messages: Belongs to the cyclin family.

8469:CNOT8
gene id: 8469:CNOT8
uniprot id: M7BMV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

8469:ADPRH
gene id: 8469:ADPRH
uniprot id: M7C300
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

8469:SHROOM1
gene id: 8469:SHROOM1
uniprot id: M7B9K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

8469:CAV3
gene id: 8469:CAV3
uniprot id: M7B8X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola
messages: sarcolemma

8469:GJB3
gene id: 8469:GJB3
uniprot id: M7C389
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8469:LOC102932967
gene id: 8469:LOC102932967
uniprot id: M7B445
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:TMED5
gene id: 8469:TMED5
uniprot id: M7BF95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

8469:PLPPR3
gene id: 8469:PLPPR3
uniprot id: M7AWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8469:ARRDC2
gene id: 8469:ARRDC2
uniprot id: M7AMW7
names: Similarity
messages: Belongs to the arrestin family.

8469:GFM1
gene id: 8469:GFM1
uniprot id: M7BL27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion

8469:ACTR1A
gene id: 8469:ACTR1A
uniprot id: M7BLL8
names: Similarity
messages: Belongs to the actin family.

8469:TMEM98
gene id: 8469:TMEM98
uniprot id: M7C9U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

8469:LOC102940776
gene id: 8469:LOC102940776
uniprot id: M7ASC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8469:LOC102946964
gene id: 8469:LOC102946964
uniprot id: M7AYJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8469:C1H11orf87
gene id: 8469:C1H11orf87
uniprot id: M7BFD7
names: Subcellular Location Annotation
messages: Membrane

8469:DAPK3
gene id: 8469:DAPK3
uniprot id: M7ANE0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8469:LOC102930284
gene id: 8469:LOC102930284
uniprot id: M7B3B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8469:BTG2
gene id: 8469:BTG2
uniprot id: M7BRX8
names: Similarity
messages: Belongs to the BTG family.

8469:GSG1
gene id: 8469:GSG1
uniprot id: M7B457
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

8469:KEF27 p12
gene id: 8469:KEF27_p12
uniprot id: Q9XPI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

8469:LOC102941689
gene id: 8469:LOC102941689
uniprot id: M7BZR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:DNAL4
gene id: 8469:DNAL4
uniprot id: M7AQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8469:CRKL
gene id: 8469:CRKL
uniprot id: M7BVI3
names: Similarity
messages: Belongs to the CRK family.

8469:INTS11
gene id: 8469:INTS11
uniprot id: M7B1L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Nucleus

8469:PIGC
gene id: 8469:PIGC
uniprot id: M7B9A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

8469:LOC102935046
gene id: 8469:LOC102935046
uniprot id: M7AQT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:NKIRAS1
gene id: 8469:NKIRAS1
uniprot id: M7B637
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

8469:FOXL2
gene id: 8469:FOXL2
uniprot id: M7BYZ7
names: Subcellular Location Annotation
messages: Nucleus

8469:GNG7
gene id: 8469:GNG7
uniprot id: M7AIF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8469:IDH1
gene id: 8469:IDH1
uniprot id: M7AIX8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

8469:NIPSNAP2
gene id: 8469:NIPSNAP2
uniprot id: M7BV51
names: Similarity
messages: Belongs to the NipSnap family.

8469:LOC102945909
gene id: 8469:LOC102945909
uniprot id: M7B294
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102938979
gene id: 8469:LOC102938979
uniprot id: M7BBX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFamide neuropeptide family.
messages: Secreted

8469:DEGS2
gene id: 8469:DEGS2
uniprot id: M7AZK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane

8469:DDIT3
gene id: 8469:DDIT3
uniprot id: M7CLE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

8469:DHFR
gene id: 8469:DHFR
uniprot id: M7AXP5
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

8469:SH3BP5L
gene id: 8469:SH3BP5L
uniprot id: M7B661
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

8469:EEF1A2
gene id: 8469:EEF1A2
uniprot id: M7C5R9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8469:SLITRK5
gene id: 8469:SLITRK5
uniprot id: M7CGE4
names: Similarity
messages: Belongs to the SLITRK family.

8469:GPR31
gene id: 8469:GPR31
uniprot id: M7AQR5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:LOC102944649
gene id: 8469:LOC102944649
uniprot id: M7AIC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8469:LOC102947053
gene id: 8469:LOC102947053
uniprot id: M7AZH5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8469:GRIA4
gene id: 8469:GRIA4
uniprot id: M7BUZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8469:SRXN1
gene id: 8469:SRXN1
uniprot id: M7B7Z9
names: Similarity
messages: Belongs to the sulfiredoxin family.

8469:VHL
gene id: 8469:VHL
uniprot id: M7BEG1
names: Similarity
messages: Belongs to the VHL family.

8469:GDAP1
gene id: 8469:GDAP1
uniprot id: M7B9N4
names: Similarity
messages: Belongs to the GST superfamily.

8469:PELO
gene id: 8469:PELO
uniprot id: M7C2K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.
messages: Nucleus

8469:GJD2
gene id: 8469:GJD2
uniprot id: M7BEW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8469:SLC52A3
gene id: 8469:SLC52A3
uniprot id: M7B5P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

8469:HOXC5
gene id: 8469:HOXC5
uniprot id: M7AXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8469:LOC102932724
gene id: 8469:LOC102932724
uniprot id: M7BRT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.
messages: Cell membrane
messages: Membrane

8469:TEX261
gene id: 8469:TEX261
uniprot id: M7BUV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

8469:LOC102945642
gene id: 8469:LOC102945642
uniprot id: M7C1M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8469:LOC102935481
gene id: 8469:LOC102935481
uniprot id: M7B9M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102933270
gene id: 8469:LOC102933270
uniprot id: M7BWV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8469:PSPH
gene id: 8469:PSPH
uniprot id: M7BYX9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

8469:LOC102931543
gene id: 8469:LOC102931543
uniprot id: M7B5J6
names: Similarity
messages: Belongs to the serpin family.

8469:ENTPD7
gene id: 8469:ENTPD7
uniprot id: M7BGX0
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8469:HOXA5
gene id: 8469:HOXA5
uniprot id: M7CA86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8469:TOB1
gene id: 8469:TOB1
uniprot id: M7B532
names: Similarity
messages: Belongs to the BTG family.

8469:RPS3A
gene id: 8469:RPS3A
uniprot id: M7C591
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Cytoplasm

8469:HOXB2
gene id: 8469:HOXB2
uniprot id: M7BDW4
names: Subcellular Location Annotation
messages: Nucleus

8469:LOC102941656
gene id: 8469:LOC102941656
uniprot id: M7B0D6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8469:LOC102934889
gene id: 8469:LOC102934889
uniprot id: M7C2S9
names: Subcellular Location Annotation
messages: Membrane

8469:NAT9
gene id: 8469:NAT9
uniprot id: M7BXB6
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

8469:SIN3A
gene id: 8469:SIN3A
uniprot id: M7APN1
names: Subcellular Location Annotation
messages: Nucleus

8469:AGTR2
gene id: 8469:AGTR2
uniprot id: M7BPK9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MTUS1.
messages: Membrane

8469:COPS5
gene id: 8469:COPS5
uniprot id: M7AYK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

8469:LOC102944707
gene id: 8469:LOC102944707
uniprot id: M7B0G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:REEP5
gene id: 8469:REEP5
uniprot id: M7BVS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

8469:TIMM10
gene id: 8469:TIMM10
uniprot id: M7BI33
names: Function
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.

8469:INS
gene id: 8469:INS
uniprot id: M7BBB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

8469:PEA15
gene id: 8469:PEA15
uniprot id: M7BCY9
names: Subcellular Location Annotation
messages: Cytoplasm

8469:ACAT2
gene id: 8469:ACAT2
uniprot id: M7BDY2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8469:RPN1
gene id: 8469:RPN1
uniprot id: M7BIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8469:RNFT2
gene id: 8469:RNFT2
uniprot id: M7B822
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102941144
gene id: 8469:LOC102941144
uniprot id: M7AIE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102936517
gene id: 8469:LOC102936517
uniprot id: M7BNJ4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:LOC102941160
gene id: 8469:LOC102941160
uniprot id: M7BPZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:HOXD3
gene id: 8469:HOXD3
uniprot id: M7BAU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8469:KCNS3
gene id: 8469:KCNS3
uniprot id: M7BYR8
names: Subcellular Location Annotation
messages: Membrane

8469:PELI3
gene id: 8469:PELI3
uniprot id: M7C470
names: Similarity
messages: Belongs to the pellino family.

8469:LOC102935163
gene id: 8469:LOC102935163
uniprot id: M7B8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8469:EEF1A1
gene id: 8469:EEF1A1
uniprot id: M7C1D2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8469:LYPLAL1
gene id: 8469:LYPLAL1
uniprot id: M7B284
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

8469:MINAR1
gene id: 8469:MINAR1
uniprot id: M7BLV2
names: Similarity
messages: Belongs to the MINAR family.

8469:LOC102941345
gene id: 8469:LOC102941345
uniprot id: M7AWR2
names: Similarity
messages: Belongs to the perilipin family.

8469:CHMP2A
gene id: 8469:CHMP2A
uniprot id: M7BKB4
names: Similarity
messages: Belongs to the SNF7 family.

8469:AMIGO1
gene id: 8469:AMIGO1
uniprot id: M7B8H7
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

8469:ORAI1
gene id: 8469:ORAI1
uniprot id: M7BGQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

8469:TSG101
gene id: 8469:TSG101
uniprot id: Q9I8G8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

8469:BTG4
gene id: 8469:BTG4
uniprot id: M7B0R4
names: Similarity
messages: Belongs to the BTG family.

8469:RAX
gene id: 8469:RAX
uniprot id: M7AN99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

8469:MAFB
gene id: 8469:MAFB
uniprot id: M7BRA1
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

8469:ANTKMT
gene id: 8469:ANTKMT
uniprot id: M7BRZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

8469:MEOX2
gene id: 8469:MEOX2
uniprot id: M7AN00
names: Subcellular Location Annotation
messages: Nucleus

8469:LOC102941956
gene id: 8469:LOC102941956
uniprot id: M7BNC8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:LOC102935573
gene id: 8469:LOC102935573
uniprot id: M7C9J1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:NKX2-2
gene id: 8469:NKX2-2
uniprot id: M7B693
names: Subcellular Location Annotation
messages: Nucleus

8469:ARMC1
gene id: 8469:ARMC1
uniprot id: M7BF64
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8469:LOC102945864
gene id: 8469:LOC102945864
uniprot id: M7C553
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8469:POU4F3
gene id: 8469:POU4F3
uniprot id: M7BYH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8469:PSMC3
gene id: 8469:PSMC3
uniprot id: M7BSX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

8469:CUEDC2
gene id: 8469:CUEDC2
uniprot id: M7BX65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

8469:RXRA
gene id: 8469:RXRA
uniprot id: M7C2J0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

8469:MTURN
gene id: 8469:MTURN
uniprot id: M7AXK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

8469:MRPL51
gene id: 8469:MRPL51
uniprot id: M7C1L7
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.

8469:LOC102946021
gene id: 8469:LOC102946021
uniprot id: M7B3A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8469:LOC102938779
gene id: 8469:LOC102938779
uniprot id: M7AUW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:DMRT3
gene id: 8469:DMRT3
uniprot id: M7BQP7
names: Similarity
messages: Belongs to the DMRT family.

8469:LOC102929656
gene id: 8469:LOC102929656
uniprot id: M7C0R1
names: Similarity
messages: Belongs to the TGF-beta family.

8469:FADS6
gene id: 8469:FADS6
uniprot id: M7B5U8
names: Similarity
messages: Belongs to the fatty acid desaturase type 1 family.

8469:PTH
gene id: 8469:PTH
uniprot id: M7BM86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8469:PAIP2
gene id: 8469:PAIP2
uniprot id: M7C731
names: Similarity
messages: Belongs to the PAIP2 family.

8469:LOC102938913
gene id: 8469:LOC102938913
uniprot id: M7C121
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

8469:KIFBP
gene id: 8469:KIFBP
uniprot id: M7BXL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

8469:MLF2
gene id: 8469:MLF2
uniprot id: M7AU41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

8469:TADA3
gene id: 8469:TADA3
uniprot id: M7AZ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

8469:FSCN1
gene id: 8469:FSCN1
uniprot id: M7B548
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

8469:COPS7B
gene id: 8469:COPS7B
uniprot id: M7AND9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

8469:CTSD
gene id: 8469:CTSD
uniprot id: M7B1R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

8469:P2RY4
gene id: 8469:P2RY4
uniprot id: M7BW44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8469:LOC102934810
gene id: 8469:LOC102934810
uniprot id: M7AL48
names: Subcellular Location Annotation
messages: Membrane

8469:GREM2
gene id: 8469:GREM2
uniprot id: M7CA48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

8469:LOC102944715
gene id: 8469:LOC102944715
uniprot id: M7C1Q7
names: Subcellular Location Annotation
messages: Membrane

8469:LOC102934946
gene id: 8469:LOC102934946
uniprot id: M7BAC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8469:RPL15
gene id: 8469:RPL15
uniprot id: M7BH99
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

8469:CLDN18
gene id: 8469:CLDN18
uniprot id: M7BKM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8469:LGALSL
gene id: 8469:LGALSL
uniprot id: M7B4U0
names: Function
messages: Does not bind lactose, and may not bind carbohydrates.

8469:LOC102936965
gene id: 8469:LOC102936965
uniprot id: M7B445
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8469:LPAR5
gene id: 8469:LPAR5
uniprot id: M7B8L7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8469:LOC102935539
gene id: 8469:LOC102935539
uniprot id: M7BDF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane