8128:LOC100698873
gene id: 8128:LOC100698873
uniprot id: A0A669CIB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8128:LOC100696178
gene id: 8128:LOC100696178
uniprot id: I3JUV4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100696694
gene id: 8128:LOC100696694
uniprot id: I3KC04
names: Similarity
messages: Belongs to the PROTOR family.

8128:LOC100697208
gene id: 8128:LOC100697208
uniprot id: I3KR25
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100712450
gene id: 8128:LOC100712450
uniprot id: I3JTR1
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

8128:LOC100691538
gene id: 8128:LOC100691538
uniprot id: A0A669BC07
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100709203
gene id: 8128:LOC100709203
uniprot id: A0A669CP92
names: Similarity
messages: Belongs to the bZIP family. Fos subfamily.

8128:LOC100696843
gene id: 8128:LOC100696843
uniprot id: A0A669CIE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

8128:LOC100697594
gene id: 8128:LOC100697594
uniprot id: A0A669B4Q0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8128:mcoln2
gene id: 8128:mcoln2
uniprot id: I3JK73
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8128:mcm8
gene id: 8128:mcm8
uniprot id: I3IYP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

8128:tmem218
gene id: 8128:tmem218
uniprot id: A0A669CVJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

8128:lg3h4orf48
gene id: 8128:lg3h4orf48
uniprot id: I3K550
names: Subcellular Location Annotation
messages: Secreted

8128:lipt2
gene id: 8128:lipt2
uniprot id: A0A669ERR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Mitochondrion

8128:LOC100695493
gene id: 8128:LOC100695493
uniprot id: I3JHR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

8128:uggt1
gene id: 8128:uggt1
uniprot id: A0A669BY82
uniprot id: A0A669CCZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

8128:LOC100692341
gene id: 8128:LOC100692341
uniprot id: I3JLK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

8128:cyld
gene id: 8128:cyld
uniprot id: A0A669BE33
uniprot id: A0A669DVL8
uniprot id: I3J3W1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

8128:LOC100690952
gene id: 8128:LOC100690952
uniprot id: A0A669E2F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8128:psmd2
gene id: 8128:psmd2
uniprot id: I3JXE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S2 family.
messages: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

8128:mtmr7
gene id: 8128:mtmr7
uniprot id: A0A669EN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

8128:LOC100707821
gene id: 8128:LOC100707821
uniprot id: I3JAB2
names: Similarity
messages: Belongs to the OSBP family.

8128:LOC100696908
gene id: 8128:LOC100696908
uniprot id: A0A669CGJ6
names: Subcellular Location Annotation
messages: Nucleus

8128:thbs1
gene id: 8128:thbs1
uniprot id: C5HIF3
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC102075588
gene id: 8128:LOC102075588
uniprot id: I3JWJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

8128:cnn3
gene id: 8128:cnn3
uniprot id: I3JTE3
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

8128:LOC100708339
gene id: 8128:LOC100708339
uniprot id: A0A669DQX6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:myh11
gene id: 8128:myh11
uniprot id: A0A669CGZ8
uniprot id: A0A669F0N3
uniprot id: I3KRL2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:rps4x
gene id: 8128:rps4x
uniprot id: A0A669E0E4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

8128:LOC100707238
gene id: 8128:LOC100707238
uniprot id: I3JU52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

8128:LOC100693841
gene id: 8128:LOC100693841
uniprot id: A0A669CRD7
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

8128:nek9
gene id: 8128:nek9
uniprot id: A0A669B8N7
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

8128:LOC100707906
gene id: 8128:LOC100707906
uniprot id: I3KFL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

8128:neu1
gene id: 8128:neu1
uniprot id: A0A0F7QWK5
uniprot id: A0A669D0S5
uniprot id: A0A669EH65
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8128:cks1b
gene id: 8128:cks1b
uniprot id: I3KUN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

8128:LOC100691491
gene id: 8128:LOC100691491
uniprot id: I3JZE4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100701922
gene id: 8128:LOC100701922
uniprot id: I3J6E5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100697195
gene id: 8128:LOC100697195
uniprot id: I3JH68
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

8128:LOC100711670
gene id: 8128:LOC100711670
uniprot id: I3JCZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:LOC100692845
gene id: 8128:LOC100692845
uniprot id: A0A669EB51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8128:LOC100707533
gene id: 8128:LOC100707533
uniprot id: I3KZ45
names: Subcellular Location Annotation
messages: Membrane

8128:tmem17
gene id: 8128:tmem17
uniprot id: I3JWC7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690343
gene id: 8128:LOC100690343
uniprot id: A0A669BKS7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693394
gene id: 8128:LOC100693394
uniprot id: A0A669BG23
uniprot id: A0A669DCY8
uniprot id: A0A669DWE8
uniprot id: A0A669EPE0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:rgs12
gene id: 8128:rgs12
uniprot id: I3KRV2
names: Subcellular Location Annotation
messages: Cytoplasm

8128:taz
gene id: 8128:taz
uniprot id: A0A669CXI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

8128:psme4
gene id: 8128:psme4
uniprot id: A0A669BP70
uniprot id: A0A669EJQ3
names: Similarity
messages: Belongs to the BLM10 family.

8128:LOC100707010
gene id: 8128:LOC100707010
uniprot id: I3K0A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8128:lg20h1orf174
gene id: 8128:lg20h1orf174
uniprot id: I3JHL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

8128:esr1
gene id: 8128:esr1
uniprot id: Q9YH33
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer. Can form a heterodimer with ER-beta (By similarity).
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Nucleus
messages: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

8128:LOC100712491
gene id: 8128:LOC100712491
uniprot id: I3J4R0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100706121
gene id: 8128:LOC100706121
uniprot id: I3JH88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

8128:foxi2
gene id: 8128:foxi2
uniprot id: I3KG76
names: Subcellular Location Annotation
messages: Nucleus

8128:opa1
gene id: 8128:opa1
uniprot id: A0A669C3B3
uniprot id: A0A669CUR0
uniprot id: I3J341
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

8128:LOC100707887
gene id: 8128:LOC100707887
uniprot id: A0A669EVC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

8128:chmp1a
gene id: 8128:chmp1a
uniprot id: I3JY27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF7 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

8128:esr2
gene id: 8128:esr2
uniprot id: A0A669EL49
uniprot id: Q1KPU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8128:LOC100700136
gene id: 8128:LOC100700136
uniprot id: I3KDK7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC100691581
gene id: 8128:LOC100691581
uniprot id: I3JSI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100692172
gene id: 8128:LOC100692172
uniprot id: A0A669EHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

8128:psmb3
gene id: 8128:psmb3
uniprot id: I3J5E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

8128:manbal
gene id: 8128:manbal
uniprot id: A0A669E2E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

8128:poll
gene id: 8128:poll
uniprot id: I3KRF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus

8128:LOC100701077
gene id: 8128:LOC100701077
uniprot id: I3KGI0
names: Subcellular Location Annotation
messages: Membrane

8128:dhrs3
gene id: 8128:dhrs3
uniprot id: I3IW24
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100703924
gene id: 8128:LOC100703924
uniprot id: A0A023ZXY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

8128:pigu
gene id: 8128:pigu
uniprot id: I3JCJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:fen1
gene id: 8128:fen1
uniprot id: I3JBG2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of fen1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

8128:LOC100690421
gene id: 8128:LOC100690421
uniprot id: A0A669ECE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

8128:LOC102075649
gene id: 8128:LOC102075649
uniprot id: A0A669F3R4
names: Similarity
messages: Belongs to the arrestin family.

8128:LOC100691800
gene id: 8128:LOC100691800
uniprot id: I3KX54
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100704453
gene id: 8128:LOC100704453
uniprot id: A0A669B252
uniprot id: A0A669CFI3
uniprot id: A0A669EUQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

8128:chek1
gene id: 8128:chek1
uniprot id: I3JBE8
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

8128:LOC102082809
gene id: 8128:LOC102082809
uniprot id: A0A669AZU9
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8128:LOC100694100
gene id: 8128:LOC100694100
uniprot id: I3K602
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
messages: extracellular space

8128:scarf2
gene id: 8128:scarf2
uniprot id: I3JWW5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100700668
gene id: 8128:LOC100700668
uniprot id: I3J728
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8128:LOC100692615
gene id: 8128:LOC100692615
uniprot id: I3K8T1
names: Similarity
messages: Belongs to the peptidase M10A family.

8128:kcns3
gene id: 8128:kcns3
uniprot id: I3KXA6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100708699
gene id: 8128:LOC100708699
uniprot id: A0A669C7K7
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

8128:tfap2c
gene id: 8128:tfap2c
uniprot id: I3JIA8
names: Similarity
messages: Belongs to the AP-2 family.

8128:LOC100705672
gene id: 8128:LOC100705672
uniprot id: I3JJ20
names: Subcellular Location Annotation
messages: Cytoplasm

8128:usp3
gene id: 8128:usp3
uniprot id: I3KDW9
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:opa3
gene id: 8128:opa3
uniprot id: I3J863
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

8128:LOC100693008
gene id: 8128:LOC100693008
uniprot id: A0A669AZA4
uniprot id: A0A669F8R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

8128:cntn5
gene id: 8128:cntn5
uniprot id: A0A669EI98
uniprot id: I3JEE0
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100708330
gene id: 8128:LOC100708330
uniprot id: I3JCN5
names: Similarity
messages: Belongs to the peptidase M10A family.

8128:hnrnpk
gene id: 8128:hnrnpk
uniprot id: I3KCP3
names: Subcellular Location Annotation
messages: nucleoplasm

8128:LOC100690615
gene id: 8128:LOC100690615
uniprot id: I3J5X3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100698040
gene id: 8128:LOC100698040
uniprot id: A0A669CC66
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

8128:b3gnt2
gene id: 8128:b3gnt2
uniprot id: I3KY39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:timm8a
gene id: 8128:timm8a
uniprot id: A0A669BNP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8128:alkal2
gene id: 8128:alkal2
uniprot id: A0A669CK06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

8128:LOC100695905
gene id: 8128:LOC100695905
uniprot id: A0A669CXA7
names: Similarity
messages: Belongs to the PACS family.

8128:LOC100703119
gene id: 8128:LOC100703119
uniprot id: I3IXB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8128:plat
gene id: 8128:plat
uniprot id: I3KAA9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:cmc1
gene id: 8128:cmc1
uniprot id: A0A669CC53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

8128:LOC100696775
gene id: 8128:LOC100696775
uniprot id: A0A669DX72
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

8128:med6
gene id: 8128:med6
uniprot id: A0A669F1L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8128:LOC100707753
gene id: 8128:LOC100707753
uniprot id: I3K4S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8128:seh1l
gene id: 8128:seh1l
uniprot id: A0A669CEZ0
uniprot id: I3JIK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
messages: Lysosome membrane
messages: kinetochore

8128:LOC102080697
gene id: 8128:LOC102080697
uniprot id: A0A669BM79
uniprot id: A0A669D7Y6
names: Similarity
messages: Belongs to the SH3RF family.

8128:LOC100534415
gene id: 8128:LOC100534415
uniprot id: A0A669D429
uniprot id: I3ITW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8128:syndig1l
gene id: 8128:syndig1l
uniprot id: A0A669D8W8
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8128:LOC100696397
gene id: 8128:LOC100696397
uniprot id: I3KJM4
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

8128:LOC100709166
gene id: 8128:LOC100709166
uniprot id: A0A669E639
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8128:ptpn14
gene id: 8128:ptpn14
uniprot id: A0A669B1A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

8128:LOC109203642
gene id: 8128:LOC109203642
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:LOC100703533
gene id: 8128:LOC100703533
uniprot id: A0A669B1N2
uniprot id: A0A669ENI4
uniprot id: A0A669EZN7
uniprot id: I3KQY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AIG1 family.
messages: Interacts with PEX19.
messages: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
messages: Membrane
messages: Peroxisome membrane

8128:LOC100708948
gene id: 8128:LOC100708948
uniprot id: A0A669F350
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:LOC100709579
gene id: 8128:LOC100709579
uniprot id: I3KSE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

8128:qrsl1
gene id: 8128:qrsl1
uniprot id: A0A669DQD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

8128:LOC112841626
gene id: 8128:LOC112841626
uniprot id: A0A669F3N9
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC102083219
gene id: 8128:LOC102083219
uniprot id: A0A669DTE3
names: Similarity
messages: Belongs to the dapper family.

8128:hsf2
gene id: 8128:hsf2
uniprot id: I3IZQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

8128:LOC100692645
gene id: 8128:LOC100692645
uniprot id: I3JSN9
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

8128:ddx59
gene id: 8128:ddx59
uniprot id: I3K3T9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

8128:dgkz
gene id: 8128:dgkz
uniprot id: I3KPA2
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8128:rnf20
gene id: 8128:rnf20
uniprot id: I3JB88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

8128:cpb1
gene id: 8128:cpb1
uniprot id: I3JEU4
names: Similarity
messages: Belongs to the peptidase M14 family.

8128:uxt
gene id: 8128:uxt
uniprot id: A0A669EWY8
names: Similarity
messages: Belongs to the UXT family.

8128:tefm
gene id: 8128:tefm
uniprot id: A0A669D848
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEFM family.
messages: Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery.
messages: mitochondrion nucleoid

8128:kpna4
gene id: 8128:kpna4
uniprot id: I3J6S5
names: Similarity
messages: Belongs to the importin alpha family.

8128:LOC100692587
gene id: 8128:LOC100692587
uniprot id: I3J5X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

8128:fgf11
gene id: 8128:fgf11
uniprot id: A0A669DXF7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:mtnr1a
gene id: 8128:mtnr1a
uniprot id: I3JV93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

8128:nme7
gene id: 8128:nme7
uniprot id: A0A669F986
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: cilium axoneme
messages: lamellipodium
messages: ruffle

8128:nf2
gene id: 8128:nf2
uniprot id: I3JWV9
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8128:lg11h8orf37
gene id: 8128:lg11h8orf37
uniprot id: I3IZ50
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

8128:march11
gene id: 8128:march11
uniprot id: A0A669DB53
names: Subcellular Location Annotation
messages: Membrane

8128:mrpl20
gene id: 8128:mrpl20
uniprot id: I3KRS3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

8128:LOC100702414
gene id: 8128:LOC100702414
uniprot id: I3JTH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8128:aimp2
gene id: 8128:aimp2
uniprot id: I3J1U1
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

8128:LOC100696191
gene id: 8128:LOC100696191
uniprot id: A0A669C201
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:lsm12
gene id: 8128:lsm12
uniprot id: I3JMA1
names: Similarity
messages: Belongs to the LSM12 family.

8128:LOC100699145
gene id: 8128:LOC100699145
uniprot id: I3KQA0
names: Subcellular Location Annotation
messages: Membrane

8128:stx7
gene id: 8128:stx7
uniprot id: A0A669B0D8
names: Similarity
messages: Belongs to the syntaxin family.

8128:LOC100696056
gene id: 8128:LOC100696056
uniprot id: I3J149
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:jag1
gene id: 8128:jag1
uniprot id: I3JUT0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8128:bloc1s6
gene id: 8128:bloc1s6
uniprot id: I3K6J9
names: Function
names: Similarity
messages: Belongs to the BLOC1S6 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

8128:LOC100702218
gene id: 8128:LOC100702218
uniprot id: I3KE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOZART2 family.
messages: centrosome
messages: spindle

8128:ndrg4
gene id: 8128:ndrg4
uniprot id: A0A669C7E0
uniprot id: I3JXP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: cytosol

8128:afap1l1
gene id: 8128:afap1l1
uniprot id: A0A669EBP3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

8128:ei24
gene id: 8128:ei24
uniprot id: A0A669BEZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EI24 family.
messages: Membrane

8128:abraxas2
gene id: 8128:abraxas2
uniprot id: A0A669EMN2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100711741
gene id: 8128:LOC100711741
uniprot id: I3J2P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

8128:LOC100711747
gene id: 8128:LOC100711747
uniprot id: A0A669BRP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:lox
gene id: 8128:lox
uniprot id: I3K8A2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8128:LOC100707183
gene id: 8128:LOC100707183
uniprot id: A0A669EC18
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:ctnnal1
gene id: 8128:ctnnal1
uniprot id: A0A669BV08
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

8128:cmpk1
gene id: 8128:cmpk1
uniprot id: A0A669ET28
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

8128:LOC100702827
gene id: 8128:LOC100702827
uniprot id: I3JLM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8128:clec16a
gene id: 8128:clec16a
uniprot id: A0A669BNS9
names: Similarity
messages: Belongs to the CLEC16A/gop-1 family.

8128:orai1
gene id: 8128:orai1
uniprot id: A0A669BBL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

8128:ncapg
gene id: 8128:ncapg
uniprot id: I3JR78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

8128:atp10a
gene id: 8128:atp10a
uniprot id: A0A669DE29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8128:LOC100709687
gene id: 8128:LOC100709687
uniprot id: A0A669DG95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

8128:ldlrad4
gene id: 8128:ldlrad4
uniprot id: A0A669AW00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

8128:hyou1
gene id: 8128:hyou1
uniprot id: A0A669BHA9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8128:LOC100710942
gene id: 8128:LOC100710942
uniprot id: F8TJW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8128:gpr34
gene id: 8128:gpr34
uniprot id: A0A669CSX2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:angptl4
gene id: 8128:angptl4
uniprot id: I3JWF5
names: Subcellular Location Annotation
messages: Secreted

8128:igfbp2
gene id: 8128:igfbp2
uniprot id: I3K6Q2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC109201907
gene id: 8128:LOC109201907
uniprot id: A0A669DXY9
names: Similarity
messages: Belongs to the globin family.

8128:LOC100712230
gene id: 8128:LOC100712230
uniprot id: A0A669EUD1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8128:LOC109194669
gene id: 8128:LOC109194669
uniprot id: A0A669DK39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100696132
gene id: 8128:LOC100696132
uniprot id: A0A669F878
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8128:snrpe
gene id: 8128:snrpe
uniprot id: A0A669EMR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

8128:LOC100693232
gene id: 8128:LOC100693232
uniprot id: A0A669CJZ9
uniprot id: A0A669CN65
uniprot id: A0A669FCC7
names: Similarity
messages: Belongs to the SH3BGR family.

8128:meox2
gene id: 8128:meox2
uniprot id: A0A669DRV0
names: Subcellular Location Annotation
messages: Nucleus

8128:gadl1
gene id: 8128:gadl1
uniprot id: A0A669CUN0
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8128:LOC100692626
gene id: 8128:LOC100692626
uniprot id: I3IV56
names: Similarity
messages: Belongs to the R-spondin family.

8128:LOC100699664
gene id: 8128:LOC100699664
uniprot id: I3J7U5
names: Similarity
messages: Belongs to the FAM83 family.

8128:hyal2
gene id: 8128:hyal2
uniprot id: I3J819
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8128:LOC100709644
gene id: 8128:LOC100709644
uniprot id: I3KJN1
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

8128:psme1
gene id: 8128:psme1
uniprot id: I3JMY4
names: Similarity
messages: Belongs to the PA28 family.

8128:LOC100697685
gene id: 8128:LOC100697685
uniprot id: I3JY25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8128:LOC100705479
gene id: 8128:LOC100705479
uniprot id: I3KTL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

8128:LOC100701948
gene id: 8128:LOC100701948
uniprot id: I3JJ89
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

8128:abhd16a
gene id: 8128:abhd16a
uniprot id: I3K5P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. ABHD16 family.
messages: Membrane

8128:LOC100710883
gene id: 8128:LOC100710883
uniprot id: A0A669CC39
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8128:LOC102079261
gene id: 8128:LOC102079261
uniprot id: A0A669E3Z9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8128:spock3
gene id: 8128:spock3
uniprot id: I3KB81
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:rpl11
gene id: 8128:rpl11
uniprot id: A0A669CZA9
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

8128:LOC100709882
gene id: 8128:LOC100709882
uniprot id: A0A669E827
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8128:LOC100704145
gene id: 8128:LOC100704145
uniprot id: A0A669CL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:LOC100693747
gene id: 8128:LOC100693747
uniprot id: A0A669EDM6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

8128:LOC100708570
gene id: 8128:LOC100708570
uniprot id: I3J023
names: Subcellular Location Annotation
messages: Nucleus

8128:spns2
gene id: 8128:spns2
uniprot id: I3KLU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

8128:taf2
gene id: 8128:taf2
uniprot id: I3JMK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

8128:eif3m
gene id: 8128:eif3m
uniprot id: I3JDN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8128:megf11
gene id: 8128:megf11
uniprot id: A0A669CFB9
uniprot id: A0A669DPS1
uniprot id: A0A669DYT1
uniprot id: A0A669EHZ7
uniprot id: I3KE67
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:naa35
gene id: 8128:naa35
uniprot id: I3KCL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

8128:LOC100709553
gene id: 8128:LOC100709553
uniprot id: A0A669C1H6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:man2b2
gene id: 8128:man2b2
uniprot id: I3JS27
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

8128:LOC100708468
gene id: 8128:LOC100708468
uniprot id: I3JBM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:tpk1
gene id: 8128:tpk1
uniprot id: A0A669CN72
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

8128:LOC100709126
gene id: 8128:LOC100709126
uniprot id: A0A669CMH8
names: Similarity
messages: Belongs to the dysbindin family.

8128:ergic1
gene id: 8128:ergic1
uniprot id: A0A669CVB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8128:LOC100696071
gene id: 8128:LOC100696071
uniprot id: I3KTF3
names: Similarity
messages: Belongs to the intermediate filament family.

8128:pyroxd1
gene id: 8128:pyroxd1
uniprot id: I3JU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: sarcomere

8128:spire2
gene id: 8128:spire2
uniprot id: A0A669AZ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

8128:fbxo25
gene id: 8128:fbxo25
uniprot id: I3K740
uniprot id: I3K741
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100699963
gene id: 8128:LOC100699963
uniprot id: A0A669D2Q1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:rpl32
gene id: 8128:rpl32
uniprot id: B3IUN6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

8128:LOC100697801
gene id: 8128:LOC100697801
uniprot id: A0A669DWQ6
uniprot id: I3JYN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

8128:LOC100707536
gene id: 8128:LOC100707536
uniprot id: A0A669CZA6
names: Similarity
messages: Belongs to the ARTD/PARP family.

8128:snrpa
gene id: 8128:snrpa
uniprot id: I3J792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM U1 A/B'' family.
messages: Nucleus

8128:LOC100692351
gene id: 8128:LOC100692351
uniprot id: A0A669F712
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8128:kif15
gene id: 8128:kif15
uniprot id: A0A669BRQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: spindle

8128:fam126b
gene id: 8128:fam126b
uniprot id: A0A669BYB6
uniprot id: A0A669C839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8128:LOC100693458
gene id: 8128:LOC100693458
uniprot id: A0A669D300
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8128:LOC100700589
gene id: 8128:LOC100700589
uniprot id: I3KKD8
names: Similarity
messages: Belongs to the GCF family.

8128:cdk19
gene id: 8128:cdk19
uniprot id: I3JZP2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:ninj1
gene id: 8128:ninj1
uniprot id: I3JJM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

8128:LOC100692380
gene id: 8128:LOC100692380
uniprot id: I3KEC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

8128:gabrb3
gene id: 8128:gabrb3
uniprot id: I3KTA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100701010
gene id: 8128:LOC100701010
uniprot id: A0A669BSG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:pax3
gene id: 8128:pax3
uniprot id: I3KBC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8128:tshz1
gene id: 8128:tshz1
uniprot id: A0A669BPL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

8128:LOC100695319
gene id: 8128:LOC100695319
uniprot id: A0A669CQT8
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

8128:LOC100701843
gene id: 8128:LOC100701843
uniprot id: I3K6G4
names: Similarity
messages: Belongs to the SLA2 family.

8128:LOC100690586
gene id: 8128:LOC100690586
uniprot id: A0A669B5H8
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

8128:ska3
gene id: 8128:ska3
uniprot id: I3KF72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

8128:hpgd
gene id: 8128:hpgd
uniprot id: I3JI20
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100704287
gene id: 8128:LOC100704287
uniprot id: A0A669EWN2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC102080582
gene id: 8128:LOC102080582
uniprot id: I3JG63
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

8128:LOC100689844
gene id: 8128:LOC100689844
uniprot id: A0A669BJD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Lysosome membrane
messages: Membrane

8128:LOC100707324
gene id: 8128:LOC100707324
uniprot id: I3IXE9
uniprot id: I3IXF0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8128:dnajc24
gene id: 8128:dnajc24
uniprot id: A0A669DJ95
names: Similarity
messages: Belongs to the DPH4 family.

8128:LOC100696010
gene id: 8128:LOC100696010
uniprot id: A0A669BAH2
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8128:LOC100708053
gene id: 8128:LOC100708053
uniprot id: I3KYC6
names: Subcellular Location Annotation
messages: Nucleus

8128:scg3
gene id: 8128:scg3
uniprot id: I3IUC4
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: secretory vesicle membrane

8128:LOC100695865
gene id: 8128:LOC100695865
uniprot id: I3KRT0
names: Similarity
messages: Belongs to the TOM1 family.

8128:LOC100709498
gene id: 8128:LOC100709498
uniprot id: A0A669F3J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

8128:ephb4
gene id: 8128:ephb4
uniprot id: A0A669B3T7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:cchcr1
gene id: 8128:cchcr1
uniprot id: A0A669ELW0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a regulator of keratinocyte proliferation or differentiation.
messages: Nucleus

8128:clcn1
gene id: 8128:clcn1
uniprot id: I3K514
names: Subcellular Location Annotation
messages: Membrane

8128:psd2
gene id: 8128:psd2
uniprot id: A0A669EV20
names: Subcellular Location Annotation
messages: ruffle membrane

8128:c9
gene id: 8128:c9
uniprot id: I3JYR0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted
messages: Target cell membrane

8128:g6pc2
gene id: 8128:g6pc2
uniprot id: I3JQG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8128:nkx2-4
gene id: 8128:nkx2-4
uniprot id: I3KR27
names: Subcellular Location Annotation
messages: Nucleus

8128:tsen15
gene id: 8128:tsen15
uniprot id: A0A669E708
names: Similarity
messages: Belongs to the SEN15 family.

8128:LOC100705514
gene id: 8128:LOC100705514
uniprot id: A0A669F3X3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:ndufb7
gene id: 8128:ndufb7
uniprot id: A0A669BHJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

8128:rag2
gene id: 8128:rag2
uniprot id: I3KXA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

8128:jpt1
gene id: 8128:jpt1
uniprot id: A0A669ER43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

8128:cplx3
gene id: 8128:cplx3
uniprot id: A0A669BIW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8128:rpl10a
gene id: 8128:rpl10a
uniprot id: A0A669CP58
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

8128:LOC100708594
gene id: 8128:LOC100708594
uniprot id: A0A669C375
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

8128:hspa9
gene id: 8128:hspa9
uniprot id: I3J8F4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8128:fahd1
gene id: 8128:fahd1
uniprot id: I3KXL6
names: Similarity
messages: Belongs to the FAH family.

8128:LOC100701968
gene id: 8128:LOC100701968
uniprot id: A0A669F8V2
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

8128:LOC100701020
gene id: 8128:LOC100701020
uniprot id: A0A669E0R0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8128:LOC100708666
gene id: 8128:LOC100708666
uniprot id: A0A669AY15
uniprot id: A0A669BTZ2
uniprot id: A0A669BWS5
names: Subcellular Location Annotation
messages: Membrane

8128:inpp5d
gene id: 8128:inpp5d
uniprot id: I3KT73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

8128:LOC100690186
gene id: 8128:LOC100690186
uniprot id: A0A669F5M7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100698021
gene id: 8128:LOC100698021
uniprot id: I3J4W0
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100700380
gene id: 8128:LOC100700380
uniprot id: I3J896
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:olfm1
gene id: 8128:olfm1
uniprot id: I3JZ46
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8128:LOC100697324
gene id: 8128:LOC100697324
uniprot id: I3K2Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

8128:LOC100695798
gene id: 8128:LOC100695798
uniprot id: A0A669DS68
uniprot id: I3KJ36
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

8128:dpt
gene id: 8128:dpt
uniprot id: I3KT85
names: Similarity
messages: Belongs to the dermatopontin family.

8128:LOC100703292
gene id: 8128:LOC100703292
uniprot id: I3K8I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

8128:sh3bp5
gene id: 8128:sh3bp5
uniprot id: A0A669CRY3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

8128:LOC100695234
gene id: 8128:LOC100695234
uniprot id: I3J1Q4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

8128:nup155
gene id: 8128:nup155
uniprot id: I3K961
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

8128:LOC100689867
gene id: 8128:LOC100689867
uniprot id: I3KUS7
names: Subcellular Location Annotation
messages: Nucleus

8128:dlgap1
gene id: 8128:dlgap1
uniprot id: A0A669CKI3
names: Similarity
messages: Belongs to the SAPAP family.

8128:LOC100702822
gene id: 8128:LOC100702822
uniprot id: A0A3G1Z143
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

8128:b4galnt4
gene id: 8128:b4galnt4
uniprot id: A0A669BGD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

8128:tmem178b
gene id: 8128:tmem178b
uniprot id: I3K9J2
names: Similarity
messages: Belongs to the TMEM178 family.

8128:vti1b
gene id: 8128:vti1b
uniprot id: I3KUB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

8128:vrtn
gene id: 8128:vrtn
uniprot id: I3IWK7
names: Similarity
messages: Belongs to the vertnin family.

8128:LOC100692518
gene id: 8128:LOC100692518
uniprot id: A0A669DLQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC100691476
gene id: 8128:LOC100691476
uniprot id: A0A669E924
names: Subcellular Location Annotation
messages: cytosol

8128:LOC100698349
gene id: 8128:LOC100698349
uniprot id: A0A669F420
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100703740
gene id: 8128:LOC100703740
uniprot id: I3KR91
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

8128:pfdn6
gene id: 8128:pfdn6
uniprot id: A0A669CD01
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

8128:fsip1
gene id: 8128:fsip1
uniprot id: I3K256
names: Similarity
messages: Belongs to the FSIP1 family.

8128:pappa
gene id: 8128:pappa
uniprot id: A0A669D4B8
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:sptssb
gene id: 8128:sptssb
uniprot id: A0A669CIZ6
uniprot id: A0A669F0C1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:ap1s1
gene id: 8128:ap1s1
uniprot id: A0A669BVU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

8128:LOC100698356
gene id: 8128:LOC100698356
uniprot id: I3KMK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8128:ndufb2
gene id: 8128:ndufb2
uniprot id: A0A669E0L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8128:LOC100693279
gene id: 8128:LOC100693279
uniprot id: A0A669C6L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100705418
gene id: 8128:LOC100705418
uniprot id: A0A669C9P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100706781
gene id: 8128:LOC100706781
uniprot id: I3IZH3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8128:LOC100696188
gene id: 8128:LOC100696188
uniprot id: I3KP27
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:yif1b
gene id: 8128:yif1b
uniprot id: I3JBR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

8128:LOC100690576
gene id: 8128:LOC100690576
uniprot id: A0A669EF39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: cytoskeleton

8128:LOC100711486
gene id: 8128:LOC100711486
uniprot id: A0A669CRC4
names: Similarity
messages: Belongs to the LEM family.

8128:LOC112841656
gene id: 8128:LOC112841656
uniprot id: A0A669AW51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8128:LOC109194281
gene id: 8128:LOC109194281
uniprot id: A0A669E8V4
names: Similarity
messages: Belongs to the DNase I family.

8128:b3gat3
gene id: 8128:b3gat3
uniprot id: A0A669C5V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:rpain
gene id: 8128:rpain
uniprot id: I3JGY0
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100701963
gene id: 8128:LOC100701963
uniprot id: A0A669C869
uniprot id: A0A669EGX4
uniprot id: I3J7P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

8128:LOC100697520
gene id: 8128:LOC100697520
uniprot id: A0A669CEQ2
uniprot id: I3KCB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100704015
gene id: 8128:LOC100704015
uniprot id: I3JVV4
names: Subcellular Location Annotation
messages: Cytoplasm

8128:chd8
gene id: 8128:chd8
uniprot id: I3KEP6
uniprot id: I3KEP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. CHD8 subfamily.
messages: Component of some MLL1/MLL complex.
messages: DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. May also act as a transcription activator by participating in efficient U6 RNA polymerase III transcription.
messages: Nucleus

8128:LOC100695152
gene id: 8128:LOC100695152
uniprot id: A0A669D1E6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

8128:sntg2
gene id: 8128:sntg2
uniprot id: I3KTT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

8128:LOC100706898
gene id: 8128:LOC100706898
uniprot id: I3K5N5
names: Subcellular Location Annotation
messages: Membrane

8128:mpp7
gene id: 8128:mpp7
uniprot id: A0A669CMP5
names: Similarity
messages: Belongs to the MAGUK family.

8128:kif21b
gene id: 8128:kif21b
uniprot id: A0A669AYR9
uniprot id: A0A669BJV5
uniprot id: A0A669FAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

8128:LOC100696772
gene id: 8128:LOC100696772
uniprot id: A0A669C4A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8128:LOC100692379
gene id: 8128:LOC100692379
uniprot id: A0A669EJV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

8128:LOC100690837
gene id: 8128:LOC100690837
uniprot id: I3K546
names: Similarity
messages: Belongs to the thioredoxin family.

8128:LOC100708375
gene id: 8128:LOC100708375
uniprot id: A0A669CMP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

8128:vsig10
gene id: 8128:vsig10
uniprot id: I3JWP4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100703747
gene id: 8128:LOC100703747
uniprot id: A0A669EU64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8128:LOC109203806
gene id: 8128:LOC109203806
uniprot id: A0A669BMR6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100692497
gene id: 8128:LOC100692497
uniprot id: A0A669CZ87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:LOC100710589
gene id: 8128:LOC100710589
uniprot id: A0A669CS42
names: Similarity
messages: Belongs to the YOS1 family.

8128:btf3
gene id: 8128:btf3
uniprot id: A0A669EXN1
names: Similarity
messages: Belongs to the NAC-beta family.

8128:elk3
gene id: 8128:elk3
uniprot id: I3JPL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:LOC109196592
gene id: 8128:LOC109196592
uniprot id: A0A669CDX5
names: Subcellular Location Annotation
messages: Nucleus

8128:slc41a2
gene id: 8128:slc41a2
uniprot id: I3K1U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8128:atxn1
gene id: 8128:atxn1
uniprot id: A0A669ELE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

8128:LOC100691901
gene id: 8128:LOC100691901
uniprot id: A0A669E134
names: Similarity
messages: Belongs to the SUA5 family.

8128:shpk
gene id: 8128:shpk
uniprot id: I3K4S5
names: Similarity
messages: Belongs to the FGGY kinase family.

8128:LOC102076204
gene id: 8128:LOC102076204
uniprot id: A0A669BE08
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693945
gene id: 8128:LOC100693945
uniprot id: A0A669ELF8
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.

8128:LOC100693192
gene id: 8128:LOC100693192
uniprot id: A0A669E7Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100697088
gene id: 8128:LOC100697088
uniprot id: I3JRB9
names: Similarity
messages: Belongs to the NXPE family.

8128:LOC100691770
gene id: 8128:LOC100691770
uniprot id: I3KXC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:sema7a
gene id: 8128:sema7a
uniprot id: I3KE06
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100693661
gene id: 8128:LOC100693661
uniprot id: I3KXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:LOC100698375
gene id: 8128:LOC100698375
uniprot id: I3J1X7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:LOC100697509
gene id: 8128:LOC100697509
uniprot id: A0A669BVF5
names: Similarity
messages: Belongs to the FAM102 family.

8128:coro6
gene id: 8128:coro6
uniprot id: I3JDR6
uniprot id: I3JDR7
names: Similarity
messages: Belongs to the WD repeat coronin family.

8128:slc26a11
gene id: 8128:slc26a11
uniprot id: A0A669E9T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

8128:LOC100698623
gene id: 8128:LOC100698623
uniprot id: I3K7Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:ppm1d
gene id: 8128:ppm1d
uniprot id: I3JWB4
names: Similarity
messages: Belongs to the PP2C family.

8128:irf6
gene id: 8128:irf6
uniprot id: I3KRX8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:LOC100701083
gene id: 8128:LOC100701083
uniprot id: I3JPI6
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8128:lmod1
gene id: 8128:lmod1
uniprot id: A0A669D7G3
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

8128:lhfpl4
gene id: 8128:lhfpl4
uniprot id: A0A669DXC3
uniprot id: I3J568
uniprot id: I3J569
names: Subcellular Location Annotation
messages: Membrane

8128:mab21l2
gene id: 8128:mab21l2
uniprot id: I3KZN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mab-21 family.
messages: Cytoplasm
messages: Nucleus

8128:hexdc
gene id: 8128:hexdc
uniprot id: A0A669DAL5
uniprot id: A0A669F2R8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

8128:prdm8
gene id: 8128:prdm8
uniprot id: I3K952
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100699127
gene id: 8128:LOC100699127
uniprot id: A0A669AZY4
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

8128:LOC100702660
gene id: 8128:LOC100702660
uniprot id: I3KJY8
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

8128:LOC100698804
gene id: 8128:LOC100698804
uniprot id: I3KMP7
names: Subcellular Location Annotation
messages: Membrane

8128:lin7c
gene id: 8128:lin7c
uniprot id: A0A669ERY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

8128:gsx2
gene id: 8128:gsx2
uniprot id: I3J4J4
names: Subcellular Location Annotation
messages: Nucleus

8128:rad51
gene id: 8128:rad51
uniprot id: Q50LF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

8128:isoc2
gene id: 8128:isoc2
uniprot id: I3K4T2
names: Similarity
messages: Belongs to the isochorismatase family.

8128:LOC100706083
gene id: 8128:LOC100706083
uniprot id: I3KPN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

8128:vangl2
gene id: 8128:vangl2
uniprot id: A0A669DJQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8128:LOC100690334
gene id: 8128:LOC100690334
uniprot id: I3KZH1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:arl3
gene id: 8128:arl3
uniprot id: I3KFL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

8128:esrrg
gene id: 8128:esrrg
uniprot id: I3KKJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8128:LOC100704480
gene id: 8128:LOC100704480
uniprot id: I3JV72
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100692125
gene id: 8128:LOC100692125
uniprot id: I3JSM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:atp9a
gene id: 8128:atp9a
uniprot id: I3KIA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8128:vps41
gene id: 8128:vps41
uniprot id: A0A669BQX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

8128:LOC100705948
gene id: 8128:LOC100705948
uniprot id: A0A669B1Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC102083301
gene id: 8128:LOC102083301
uniprot id: I3KDX6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100697439
gene id: 8128:LOC100697439
uniprot id: I3JC29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100707632
gene id: 8128:LOC100707632
uniprot id: I3K1M0
names: Similarity
messages: Belongs to the SAPS family.

8128:LOC100691479
gene id: 8128:LOC100691479
uniprot id: A0A669EFP0
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100702161
gene id: 8128:LOC100702161
uniprot id: I3IXJ2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:LOC100710498
gene id: 8128:LOC100710498
uniprot id: I3KDL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

8128:gem
gene id: 8128:gem
uniprot id: I3JFJ9
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

8128:tollip
gene id: 8128:tollip
uniprot id: A0A669CGH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tollip family.
messages: Cytoplasm

8128:LOC100703972
gene id: 8128:LOC100703972
uniprot id: I3KSR0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100689749
gene id: 8128:LOC100689749
uniprot id: A0A669E2D7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8128:npr3
gene id: 8128:npr3
uniprot id: A0A669BEY5
names: Subcellular Location Annotation
messages: Membrane

8128:tmem86a
gene id: 8128:tmem86a
uniprot id: A0A669DV61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

8128:stt3a
gene id: 8128:stt3a
uniprot id: A0A669DA57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

8128:tmem106b
gene id: 8128:tmem106b
uniprot id: I3JH96
names: Similarity
messages: Belongs to the TMEM106 family.

8128:LOC100695893
gene id: 8128:LOC100695893
uniprot id: I3KHP2
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100691526
gene id: 8128:LOC100691526
uniprot id: I3IWP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

8128:LOC100707779
gene id: 8128:LOC100707779
uniprot id: A0A669B945
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

8128:LOC100710496
gene id: 8128:LOC100710496
uniprot id: I3J4V5
uniprot id: I3J4V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

8128:axl
gene id: 8128:axl
uniprot id: A0A669EPB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

8128:LOC100696657
gene id: 8128:LOC100696657
uniprot id: I3J4S2
names: Similarity
messages: Belongs to the stathmin family.

8128:LOC106098551
gene id: 8128:LOC106098551
uniprot id: I3KGT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Membrane raft

8128:enpp4
gene id: 8128:enpp4
uniprot id: A0A669DI98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Cell membrane
messages: Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
messages: Membrane

8128:LOC100702162
gene id: 8128:LOC100702162
uniprot id: I3K1G5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Recycling endosome membrane

8128:LOC109195544
gene id: 8128:LOC109195544
uniprot id: A0A669E2J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8128:LOC100692119
gene id: 8128:LOC100692119
uniprot id: I3J5G4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

8128:LOC102076968
gene id: 8128:LOC102076968
uniprot id: A0A669CWB1
names: Similarity
messages: Belongs to the FAM83 family.

8128:nr6a1
gene id: 8128:nr6a1
uniprot id: A0A669EF09
uniprot id: A0A669EMY6
uniprot id: A0A669F7F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:gdpd2
gene id: 8128:gdpd2
uniprot id: I3J3P9
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8128:LOC100703890
gene id: 8128:LOC100703890
uniprot id: A0A669AWB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

8128:LOC100690541
gene id: 8128:LOC100690541
uniprot id: I3JNE8
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

8128:LOC100698512
gene id: 8128:LOC100698512
uniprot id: A0A669F6Z3
uniprot id: I3K491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: cytoskeleton

8128:trpt1
gene id: 8128:trpt1
uniprot id: I3JCW7
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

8128:mrps11
gene id: 8128:mrps11
uniprot id: A0A669CGG0
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

8128:ap1s3
gene id: 8128:ap1s3
uniprot id: I3KBE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

8128:LOC109202927
gene id: 8128:LOC109202927
uniprot id: A0A669EMN1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8128:LOC100691426
gene id: 8128:LOC100691426
uniprot id: A0A669B2H7
names: Similarity
messages: Belongs to the IL-6 superfamily.

8128:six4
gene id: 8128:six4
uniprot id: I3KW46
names: Subcellular Location Annotation
messages: Nucleus

8128:foxl2
gene id: 8128:foxl2
uniprot id: Q6JA05
names: Subcellular Location Annotation
messages: Nucleus

8128:ddx43
gene id: 8128:ddx43
uniprot id: I3IY20
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:cacng5
gene id: 8128:cacng5
uniprot id: A0A669CEI6
uniprot id: A0A669DLS3
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

8128:apoa4b
gene id: 8128:apoa4b
uniprot id: I3KGU7
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8128:LOC100705528
gene id: 8128:LOC100705528
uniprot id: A0A669F5T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Exhibits natriuretic and vasodepressant activity. Has cGMP-stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
messages: Secreted

8128:LOC102081934
gene id: 8128:LOC102081934
uniprot id: A0A669BY68
names: Similarity
messages: Belongs to the FAM83 family.

8128:ctdp1
gene id: 8128:ctdp1
uniprot id: A0A669D1Q4
uniprot id: I3JLE3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

8128:LOC100706166
gene id: 8128:LOC100706166
uniprot id: I3JIS5
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100693392
gene id: 8128:LOC100693392
uniprot id: A0A669F7A1
uniprot id: I3JW87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

8128:pi4k2a
gene id: 8128:pi4k2a
uniprot id: I3KME4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

8128:LOC100711213
gene id: 8128:LOC100711213
uniprot id: I3K4L0
names: Similarity
messages: Belongs to the BicD family.

8128:mfn1
gene id: 8128:mfn1
uniprot id: I3IZN9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8128:LOC100704783
gene id: 8128:LOC100704783
uniprot id: I3J6N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

8128:LOC100696814
gene id: 8128:LOC100696814
uniprot id: A0A669E7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

8128:cdipt
gene id: 8128:cdipt
uniprot id: I3JSH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

8128:LOC100706564
gene id: 8128:LOC100706564
uniprot id: I3K788
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

8128:LOC100711905
gene id: 8128:LOC100711905
uniprot id: I3KYM1
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

8128:LOC100712021
gene id: 8128:LOC100712021
uniprot id: A0A669BI44
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

8128:LOC100712389
gene id: 8128:LOC100712389
uniprot id: A0A669EYR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

8128:tspan17
gene id: 8128:tspan17
uniprot id: A0A669C2Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:sgcd
gene id: 8128:sgcd
uniprot id: A0A669B7D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

8128:dnaaf1
gene id: 8128:dnaaf1
uniprot id: I3JDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF1 family.
messages: cilium

8128:rpl15
gene id: 8128:rpl15
uniprot id: I3JVR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

8128:frem3
gene id: 8128:frem3
uniprot id: A0A669E811
names: Similarity
messages: Belongs to the FRAS1 family.

8128:syngr1
gene id: 8128:syngr1
uniprot id: I3K8F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

8128:LOC100712468
gene id: 8128:LOC100712468
uniprot id: I3JP62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:tmc7
gene id: 8128:tmc7
uniprot id: I3KRK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

8128:baz1b
gene id: 8128:baz1b
uniprot id: A0A669B740
uniprot id: A0A669BDP4
names: Subcellular Location Annotation
messages: Nucleus

8128:timp4
gene id: 8128:timp4
uniprot id: I3KA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Secreted

8128:batf
gene id: 8128:batf
uniprot id: A0A669CI65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

8128:hoxd9
gene id: 8128:hoxd9
uniprot id: A0A669C5A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8128:LOC100704130
gene id: 8128:LOC100704130
uniprot id: I3KJJ1
names: Similarity
messages: Belongs to the BicD family.

8128:vps54
gene id: 8128:vps54
uniprot id: I3KGA0
names: Similarity
messages: Belongs to the VPS54 family.

8128:nr3c2
gene id: 8128:nr3c2
uniprot id: I3JUR6
names: Subcellular Location Annotation
messages: Nucleus

8128:nfasc
gene id: 8128:nfasc
uniprot id: A0A669ETK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

8128:LOC100694538
gene id: 8128:LOC100694538
uniprot id: I3K8S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8128:ormdl1
gene id: 8128:ormdl1
uniprot id: I3KPD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

8128:map3k12
gene id: 8128:map3k12
uniprot id: A0A669CM62
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: May be an activator of the JNK/SAPK pathway.

8128:LOC109201906
gene id: 8128:LOC109201906
uniprot id: A0A669DXY9
names: Similarity
messages: Belongs to the globin family.

8128:kri1
gene id: 8128:kri1
uniprot id: I3JNA1
names: Similarity
messages: Belongs to the KRI1 family.

8128:LOC102079252
gene id: 8128:LOC102079252
uniprot id: I3JRE9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:rln3
gene id: 8128:rln3
uniprot id: I3KMI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8128:lsm1
gene id: 8128:lsm1
uniprot id: I3JXG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

8128:LOC100712332
gene id: 8128:LOC100712332
uniprot id: A0A669DDY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

8128:adra2c
gene id: 8128:adra2c
uniprot id: I3KYE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:cacng1
gene id: 8128:cacng1
uniprot id: A0A669E9R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

8128:LOC100696419
gene id: 8128:LOC100696419
uniprot id: I3KJL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

8128:LOC100704409
gene id: 8128:LOC100704409
uniprot id: A0A669C3M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:mcm4
gene id: 8128:mcm4
uniprot id: I3JSZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

8128:LOC100710500
gene id: 8128:LOC100710500
uniprot id: I3K896
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8128:arv1
gene id: 8128:arv1
uniprot id: I3KPL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

8128:LOC100710535
gene id: 8128:LOC100710535
uniprot id: I3JB62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100703727
gene id: 8128:LOC100703727
uniprot id: I3JZ84
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

8128:LOC100697794
gene id: 8128:LOC100697794
uniprot id: I3KP74
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8128:rars2
gene id: 8128:rars2
uniprot id: I3JET9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8128:LOC109195519
gene id: 8128:LOC109195519
uniprot id: A0A669DVY9
names: Similarity
messages: Belongs to the apolipoprotein L family.

8128:LOC100695242
gene id: 8128:LOC100695242
uniprot id: I3KW52
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:slc17a9
gene id: 8128:slc17a9
uniprot id: A0A669EAH3
names: Subcellular Location Annotation
messages: Membrane

8128:ggcx
gene id: 8128:ggcx
uniprot id: A0A669ESK1
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.
messages: Membrane

8128:LOC100711592
gene id: 8128:LOC100711592
uniprot id: A0A669CAJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

8128:LOC100706435
gene id: 8128:LOC100706435
uniprot id: A0A669EUX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

8128:LOC100700083
gene id: 8128:LOC100700083
uniprot id: B6E947
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8128:fgf1
gene id: 8128:fgf1
uniprot id: A0A669BFB0
uniprot id: A0A669ENK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

8128:LOC100711569
gene id: 8128:LOC100711569
uniprot id: A0A669DFQ5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:yrdc
gene id: 8128:yrdc
uniprot id: I3KH19
names: Similarity
messages: Belongs to the SUA5 family.

8128:lg7h11orf58
gene id: 8128:lg7h11orf58
uniprot id: A0A669ETC7
names: Similarity
messages: Belongs to the SMAP family.

8128:ppm1b
gene id: 8128:ppm1b
uniprot id: I3IX31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8128:ints2
gene id: 8128:ints2
uniprot id: I3KLY6
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

8128:LOC100697282
gene id: 8128:LOC100697282
uniprot id: A0A669BKW8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100699599
gene id: 8128:LOC100699599
uniprot id: A0A669CR21
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

8128:tsnax
gene id: 8128:tsnax
uniprot id: I3JV36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

8128:LOC100697912
gene id: 8128:LOC100697912
uniprot id: I3KBJ5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8128:ndufv1
gene id: 8128:ndufv1
uniprot id: A0A669EQ66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

8128:adcy8
gene id: 8128:adcy8
uniprot id: A0A669C0R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8128:bcap29
gene id: 8128:bcap29
uniprot id: I3JBN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

8128:LOC100712052
gene id: 8128:LOC100712052
uniprot id: A0A669CQH5
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8128:LOC100702028
gene id: 8128:LOC100702028
uniprot id: A0A669FBL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:st18
gene id: 8128:st18
uniprot id: I3JSX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

8128:LOC100698110
gene id: 8128:LOC100698110
uniprot id: I3IV23
names: Similarity
messages: Belongs to the dickkopf family.

8128:yars2
gene id: 8128:yars2
uniprot id: I3JQG0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8128:LOC106097969
gene id: 8128:LOC106097969
uniprot id: A0A669DYB2
names: Similarity
messages: Belongs to the peptidase M10A family.

8128:xpo5
gene id: 8128:xpo5
uniprot id: I3KQ49
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100707770
gene id: 8128:LOC100707770
uniprot id: I3JU54
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

8128:eif4e3
gene id: 8128:eif4e3
uniprot id: I3KWP0
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

8128:edem3
gene id: 8128:edem3
uniprot id: I3JAP7
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8128:LOC100700789
gene id: 8128:LOC100700789
uniprot id: I3JTB1
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100703406
gene id: 8128:LOC100703406
uniprot id: I3JXR1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100703683
gene id: 8128:LOC100703683
uniprot id: A0A669BUK6
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100702606
gene id: 8128:LOC100702606
uniprot id: I3KCC2
names: Subcellular Location Annotation
messages: Membrane

8128:gtf2h3
gene id: 8128:gtf2h3
uniprot id: I3K6A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

8128:tbpl1
gene id: 8128:tbpl1
uniprot id: I3IVC7
names: Similarity
messages: Belongs to the TBP family.

8128:necap2
gene id: 8128:necap2
uniprot id: A0A669BUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

8128:pcsk9
gene id: 8128:pcsk9
uniprot id: I3J3V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell surface
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Endosome
messages: Golgi apparatus
messages: Lysosome

8128:eya1
gene id: 8128:eya1
uniprot id: A0A669F9Y1
uniprot id: I3K9Z5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

8128:LOC100705067
gene id: 8128:LOC100705067
uniprot id: I3JWB3
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

8128:hcfc2
gene id: 8128:hcfc2
uniprot id: I3K160
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100704828
gene id: 8128:LOC100704828
uniprot id: I3KQH1
names: Similarity
messages: Belongs to the CBP3 family.

8128:LOC100697991
gene id: 8128:LOC100697991
uniprot id: A0A669ETZ3
uniprot id: I3K1F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

8128:lg13h10orf53
gene id: 8128:lg13h10orf53
uniprot id: I3KQ80
names: Similarity
messages: Belongs to the UPF0728 family.

8128:slc25a16
gene id: 8128:slc25a16
uniprot id: I3KPW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:ghrh
gene id: 8128:ghrh
uniprot id: I3KWM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8128:LOC100704763
gene id: 8128:LOC100704763
uniprot id: I3KZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100696907
gene id: 8128:LOC100696907
uniprot id: I3KQ86
names: Subcellular Location Annotation
messages: Membrane

8128:fam189a1
gene id: 8128:fam189a1
uniprot id: I3JG59
names: Similarity
messages: Belongs to the ENTREP family.

8128:creld2
gene id: 8128:creld2
uniprot id: A0A669DW93
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100710697
gene id: 8128:LOC100710697
uniprot id: I3J3S7
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

8128:dusp5
gene id: 8128:dusp5
uniprot id: I3KHD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

8128:tmem161b
gene id: 8128:tmem161b
uniprot id: A0A669F4Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

8128:mmp23b
gene id: 8128:mmp23b
uniprot id: I3JH78
names: Caution
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC102078990
gene id: 8128:LOC102078990
uniprot id: A0A669BTI2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:ndp
gene id: 8128:ndp
uniprot id: A0A669DVU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:gapdhs
gene id: 8128:gapdhs
uniprot id: G3LHF4
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

8128:LOC100691100
gene id: 8128:LOC100691100
uniprot id: I3KNT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

8128:lg7h11orf49
gene id: 8128:lg7h11orf49
uniprot id: A0A669E1Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: centriolar satellite

8128:LOC100702425
gene id: 8128:LOC100702425
uniprot id: I3JH17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8128:btbd10
gene id: 8128:btbd10
uniprot id: A0A669F4J3
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100699081
gene id: 8128:LOC100699081
uniprot id: I3JUX4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100695799
gene id: 8128:LOC100695799
uniprot id: I3KNE1
uniprot id: I3KNE2
names: Similarity
messages: Belongs to the serpin family.
messages: Belongs to the serpin family. Ov-serpin subfamily.

8128:gtf2a1
gene id: 8128:gtf2a1
uniprot id: I3IXX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

8128:med24
gene id: 8128:med24
uniprot id: I3KVF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

8128:LOC102082411
gene id: 8128:LOC102082411
uniprot id: I3JNS2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100707314
gene id: 8128:LOC100707314
uniprot id: I3K5D2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:rps15
gene id: 8128:rps15
uniprot id: A0A669D4F5
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

8128:LOC100707881
gene id: 8128:LOC100707881
uniprot id: I3KZ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8128:syt1
gene id: 8128:syt1
uniprot id: I3ITR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

8128:rae1
gene id: 8128:rae1
uniprot id: I3KWW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat rae1 family.
messages: spindle pole

8128:rag1
gene id: 8128:rag1
uniprot id: I3KB69
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

8128:cfap410
gene id: 8128:cfap410
uniprot id: A0A669BU64
names: Similarity
messages: Belongs to the SDS22 family.

8128:naga
gene id: 8128:naga
uniprot id: A0A669EQ22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

8128:LOC100690211
gene id: 8128:LOC100690211
uniprot id: I3KQ81
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8128:cplane2
gene id: 8128:cplane2
uniprot id: A0A669ER79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
messages: cilium basal body

8128:LOC100709208
gene id: 8128:LOC100709208
uniprot id: I3KNJ2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC102079959
gene id: 8128:LOC102079959
uniprot id: A0A669DN51
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8128:LOC100534438
gene id: 8128:LOC100534438
uniprot id: I6LL60
names: Similarity
messages: Belongs to the peptidase C14A family.

8128:LOC100704348
gene id: 8128:LOC100704348
uniprot id: I3K1M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8128:LOC109204180
gene id: 8128:LOC109204180
uniprot id: A0A669CJS4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC109194212
gene id: 8128:LOC109194212
uniprot id: A0A669BIA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:dhrs1
gene id: 8128:dhrs1
uniprot id: I3KEM1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100708691
gene id: 8128:LOC100708691
uniprot id: I3IWY6
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8128:cyr61
gene id: 8128:cyr61
uniprot id: I3JQK2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100696615
gene id: 8128:LOC100696615
uniprot id: I3JCA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100711712
gene id: 8128:LOC100711712
uniprot id: A0A669DCU4
uniprot id: I3KAX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:lrfn5
gene id: 8128:lrfn5
uniprot id: A0A669B5A9
names: Subcellular Location Annotation
messages: Membrane

8128:mtmr11
gene id: 8128:mtmr11
uniprot id: I3JPM1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8128:LOC100711297
gene id: 8128:LOC100711297
uniprot id: I3JX46
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

8128:LOC100698715
gene id: 8128:LOC100698715
uniprot id: I3JWL1
names: Similarity
messages: Belongs to the GADD45 family.
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

8128:adssl1
gene id: 8128:adssl1
uniprot id: I3K2F0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

8128:LOC109196647
gene id: 8128:LOC109196647
uniprot id: I3JXP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8128:pus10
gene id: 8128:pus10
uniprot id: I3ITV4
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

8128:lyrm2
gene id: 8128:lyrm2
uniprot id: A0A669DSJ5
names: Similarity
messages: Belongs to the complex I LYR family.

8128:LOC100699048
gene id: 8128:LOC100699048
uniprot id: A0A669F766
names: Subcellular Location Annotation
messages: Membrane

8128:celsr1
gene id: 8128:celsr1
uniprot id: A0A669AZ57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

8128:gys2
gene id: 8128:gys2
uniprot id: A0A669DB87
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

8128:llph
gene id: 8128:llph
uniprot id: I3ITS5
names: Similarity
messages: Belongs to the learning-associated protein family.

8128:LOC100706931
gene id: 8128:LOC100706931
uniprot id: I3KGP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

8128:pcsk5
gene id: 8128:pcsk5
uniprot id: A0A669ESA5
names: Similarity
messages: Belongs to the peptidase S8 family.

8128:acsf3
gene id: 8128:acsf3
uniprot id: A0A669DUD1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8128:LOC102080922
gene id: 8128:LOC102080922
uniprot id: I3JVW8
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100704429
gene id: 8128:LOC100704429
uniprot id: I3K225
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

8128:ap3s1
gene id: 8128:ap3s1
uniprot id: A0A669DRD3
uniprot id: I3KAR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

8128:LOC109194425
gene id: 8128:LOC109194425
uniprot id: I3KC98
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100694673
gene id: 8128:LOC100694673
uniprot id: A0A669B490
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

8128:rplp0
gene id: 8128:rplp0
uniprot id: I3KTM3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

8128:soat1
gene id: 8128:soat1
uniprot id: A0A669CTW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:anxa10
gene id: 8128:anxa10
uniprot id: A7YIG9
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8128:LOC100691959
gene id: 8128:LOC100691959
uniprot id: I3J605
uniprot id: I3J606
names: Similarity
messages: Belongs to the intermediate filament family.

8128:LOC106096671
gene id: 8128:LOC106096671
uniprot id: I3J8R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8128:gnptab
gene id: 8128:gnptab
uniprot id: A0A669DCA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stealth family.
messages: Membrane

8128:gcm2
gene id: 8128:gcm2
uniprot id: I3JU77
names: Subcellular Location Annotation
messages: Nucleus

8128:ddx11
gene id: 8128:ddx11
uniprot id: A0A669DZE5
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

8128:LOC100692792
gene id: 8128:LOC100692792
uniprot id: A0A669EAB4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100700256
gene id: 8128:LOC100700256
uniprot id: I3JEQ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

8128:LOC100708779
gene id: 8128:LOC100708779
uniprot id: A0A669BZ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8128:LOC100703716
gene id: 8128:LOC100703716
uniprot id: A0A669E377
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

8128:LOC100704324
gene id: 8128:LOC100704324
uniprot id: I3IXN2
names: Similarity
messages: Belongs to the isthmin family.

8128:LOC100691514
gene id: 8128:LOC100691514
uniprot id: I3JJ46
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:me1
gene id: 8128:me1
uniprot id: A0A669BAC9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

8128:ttyh3
gene id: 8128:ttyh3
uniprot id: I3IYG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8128:LOC100708488
gene id: 8128:LOC100708488
uniprot id: I3J5D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8128:LOC100711225
gene id: 8128:LOC100711225
uniprot id: I3JKE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

8128:LOC100709328
gene id: 8128:LOC100709328
uniprot id: A0A669BTW3
names: Similarity
messages: Belongs to the stathmin family.

8128:sptlc2
gene id: 8128:sptlc2
uniprot id: I3IXN5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

8128:scmh1
gene id: 8128:scmh1
uniprot id: A0A669B7D5
uniprot id: A0A669DL35
uniprot id: I3KGY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

8128:cdca7l
gene id: 8128:cdca7l
uniprot id: I3JXT6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:cntnap1
gene id: 8128:cntnap1
uniprot id: I3IY59
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: paranodal septate junction

8128:ppp1r16b
gene id: 8128:ppp1r16b
uniprot id: A0A669E6F4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:prr5l
gene id: 8128:prr5l
uniprot id: I3J8L5
names: Similarity
messages: Belongs to the PROTOR family.

8128:LOC106098741
gene id: 8128:LOC106098741
uniprot id: A0A669FAP1
names: Subcellular Location Annotation
messages: Nucleus

8128:map3k21
gene id: 8128:map3k21
uniprot id: I3IWQ9
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

8128:ccna1
gene id: 8128:ccna1
uniprot id: I3K449
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8128:LOC100707896
gene id: 8128:LOC100707896
uniprot id: I3K2P4
names: Subcellular Location Annotation
messages: Secreted

8128:LOC100703179
gene id: 8128:LOC100703179
uniprot id: I3J859
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8128:LOC100700674
gene id: 8128:LOC100700674
uniprot id: A0A669BL99
uniprot id: A0A669D8V5
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

8128:LOC100695551
gene id: 8128:LOC100695551
uniprot id: A0A669BNM0
names: Subcellular Location Annotation
messages: Membrane

8128:cog1
gene id: 8128:cog1
uniprot id: I3JM29
names: Similarity
messages: Belongs to the COG1 family.

8128:LOC102079122
gene id: 8128:LOC102079122
uniprot id: A0A669E8V0
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

8128:LOC100702180
gene id: 8128:LOC100702180
uniprot id: A0A669F2C1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:ptpa
gene id: 8128:ptpa
uniprot id: I3K429
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8128:LOC102079012
gene id: 8128:LOC102079012
uniprot id: A0A669CH85
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100534493
gene id: 8128:LOC100534493
uniprot id: I3KSU1
names: Similarity
messages: Belongs to the TGF-beta family.

8128:dph2
gene id: 8128:dph2
uniprot id: I3JBD0
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

8128:ald
gene id: 8128:ald
uniprot id: I3KW15
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

8128:kif14
gene id: 8128:kif14
uniprot id: I3K3T6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:dok1
gene id: 8128:dok1
uniprot id: A0A669F3I1
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

8128:med21
gene id: 8128:med21
uniprot id: A0A669B7U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8128:blm
gene id: 8128:blm
uniprot id: A0A669C3Z0
uniprot id: I3KDC9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

8128:LOC100697215
gene id: 8128:LOC100697215
uniprot id: A0A669DEN0
names: Similarity
messages: Belongs to the arrestin family.

8128:elac1
gene id: 8128:elac1
uniprot id: I3KCY9
names: Subunit
messages: Homodimer.

8128:tfdp1
gene id: 8128:tfdp1
uniprot id: I3K9P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8128:npc2
gene id: 8128:npc2
uniprot id: I3KWC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

8128:pacs1
gene id: 8128:pacs1
uniprot id: I3K5M7
names: Similarity
messages: Belongs to the PACS family.

8128:LOC109194297
gene id: 8128:LOC109194297
uniprot id: A0A669BNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8128:plcd4
gene id: 8128:plcd4
uniprot id: I3JJJ7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Nucleus

8128:rps13
gene id: 8128:rps13
uniprot id: A0A669E6V5
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

8128:nip7
gene id: 8128:nip7
uniprot id: I3KKM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

8128:LOC100707727
gene id: 8128:LOC100707727
uniprot id: A0A669C1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:ptgdsl2
gene id: 8128:ptgdsl2
uniprot id: I7I7M1
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8128:LOC100703997
gene id: 8128:LOC100703997
uniprot id: A0A669CQA9
uniprot id: A0A669D6J6
names: Similarity
messages: Belongs to the MAP7 family.

8128:LOC100705711
gene id: 8128:LOC100705711
uniprot id: A0A669CBA5
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100699994
gene id: 8128:LOC100699994
uniprot id: I3K1F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: centriole
messages: cilium basal body

8128:zfpm1
gene id: 8128:zfpm1
uniprot id: A0A669D1J2
uniprot id: A0A669F137
names: Subcellular Location Annotation
messages: Nucleus

8128:lg12h12orf49
gene id: 8128:lg12h12orf49
uniprot id: I3JWU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100708768
gene id: 8128:LOC100708768
uniprot id: A0A669D636
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100699266
gene id: 8128:LOC100699266
uniprot id: I3J4Y4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8128:LOC100699041
gene id: 8128:LOC100699041
uniprot id: I3J087
names: Subcellular Location Annotation
messages: Membrane

8128:LOC102078090
gene id: 8128:LOC102078090
uniprot id: I3K824
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:LOC100696490
gene id: 8128:LOC100696490
uniprot id: I3KZM8
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8128:LOC100701503
gene id: 8128:LOC100701503
uniprot id: I3IVM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:slc25a48
gene id: 8128:slc25a48
uniprot id: I3J951
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC100705048
gene id: 8128:LOC100705048
uniprot id: A0A669CBE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8128:LOC100704433
gene id: 8128:LOC100704433
uniprot id: I3J8P7
names: Subcellular Location Annotation
messages: Nucleus

8128:prkci
gene id: 8128:prkci
uniprot id: I3KQP3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

8128:hmbs
gene id: 8128:hmbs
uniprot id: A0A669EJ21
uniprot id: A0A669F2Z4
names: Similarity
messages: Belongs to the HMBS family.

8128:LOC100690032
gene id: 8128:LOC100690032
uniprot id: I3J8D1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100689988
gene id: 8128:LOC100689988
uniprot id: I3JJQ8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:stat4
gene id: 8128:stat4
uniprot id: I3KJ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8128:crb2
gene id: 8128:crb2
uniprot id: I3KWI2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:sh3pxd2a
gene id: 8128:sh3pxd2a
uniprot id: I3IV77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

8128:LOC100690306
gene id: 8128:LOC100690306
uniprot id: I3JKW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

8128:pgm2
gene id: 8128:pgm2
uniprot id: I3JQW5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8128:LOC100694785
gene id: 8128:LOC100694785
uniprot id: I3KIN5
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

8128:LOC100706200
gene id: 8128:LOC100706200
uniprot id: I3IY58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8128:hoxd10
gene id: 8128:hoxd10
uniprot id: I3JPN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8128:LOC100702854
gene id: 8128:LOC100702854
uniprot id: I3KRY7
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:LOC100692318
gene id: 8128:LOC100692318
uniprot id: A0A669B0W9
names: Subcellular Location Annotation
messages: Secreted

8128:engase
gene id: 8128:engase
uniprot id: I3JG51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

8128:LOC100692553
gene id: 8128:LOC100692553
uniprot id: I3KUG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

8128:LOC100701121
gene id: 8128:LOC100701121
uniprot id: I3K6Y6
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

8128:LOC100704291
gene id: 8128:LOC100704291
uniprot id: A0A669DRJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

8128:LOC100697940
gene id: 8128:LOC100697940
uniprot id: I3JP38
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100710958
gene id: 8128:LOC100710958
uniprot id: I3KXG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100706733
gene id: 8128:LOC100706733
uniprot id: A0A669BL75
names: Subcellular Location Annotation
messages: Membrane

8128:LOC102079182
gene id: 8128:LOC102079182
uniprot id: A0A669C0W7
names: Subcellular Location Annotation
messages: Membrane

8128:syt14
gene id: 8128:syt14
uniprot id: I3JNF4
names: Similarity
messages: Belongs to the synaptotagmin family.

8128:nudt15
gene id: 8128:nudt15
uniprot id: A0A669CZM6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

8128:LOC100704738
gene id: 8128:LOC100704738
uniprot id: I3JR17
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:LOC100701313
gene id: 8128:LOC100701313
uniprot id: I3IVT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8128:tgfb3
gene id: 8128:tgfb3
uniprot id: I3KWE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

8128:LOC100689746
gene id: 8128:LOC100689746
uniprot id: I3K0V0
names: Similarity
messages: Belongs to the PROTOR family.

8128:galnt1
gene id: 8128:galnt1
uniprot id: A0A669CXY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:clrn2
gene id: 8128:clrn2
uniprot id: A0A669B5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

8128:fubp1
gene id: 8128:fubp1
uniprot id: I3KPU6
names: Subcellular Location Annotation
messages: Nucleus

8128:cux1
gene id: 8128:cux1
uniprot id: I3J7D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC102075875
gene id: 8128:LOC102075875
uniprot id: I3JNN2
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

8128:cfap36
gene id: 8128:cfap36
uniprot id: I3IX84
uniprot id: I3IX85
names: Similarity
messages: Belongs to the CFAP36 family.

8128:LOC100702900
gene id: 8128:LOC100702900
uniprot id: I3JNU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:sema6d
gene id: 8128:sema6d
uniprot id: A0A669DJ73
uniprot id: A0A669DZW6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100707964
gene id: 8128:LOC100707964
uniprot id: I3J3X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:LOC106097938
gene id: 8128:LOC106097938
uniprot id: A0A669F583
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8128:LOC100695832
gene id: 8128:LOC100695832
uniprot id: A0A669E9E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

8128:pigx
gene id: 8128:pigx
uniprot id: I3J3X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.

8128:LOC100699133
gene id: 8128:LOC100699133
uniprot id: I3J7X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:hoxb9
gene id: 8128:hoxb9
uniprot id: I3JFZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8128:LOC100699923
gene id: 8128:LOC100699923
uniprot id: A0A669C7E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

8128:wisp2
gene id: 8128:wisp2
uniprot id: I3KI41
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC102075670
gene id: 8128:LOC102075670
uniprot id: I3KMM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Cytoplasmic vesicle
messages: Vesicle
messages: axon
messages: dendrite

8128:LOC100698203
gene id: 8128:LOC100698203
uniprot id: A0A669DFT8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

8128:LOC100696162
gene id: 8128:LOC100696162
uniprot id: I3K2J9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8128:dip2c
gene id: 8128:dip2c
uniprot id: A0A669C3P2
uniprot id: I3KMH0
names: Similarity
messages: Belongs to the DIP2 family.

8128:urad
gene id: 8128:urad
uniprot id: I3K9H9
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

8128:LOC100706133
gene id: 8128:LOC100706133
uniprot id: I3IY63
names: Subcellular Location Annotation
messages: Membrane

8128:pros1
gene id: 8128:pros1
uniprot id: A0A669D496
names: Caution
names: Function
messages: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:tsta3
gene id: 8128:tsta3
uniprot id: I3JYA0
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

8128:sde2
gene id: 8128:sde2
uniprot id: I3JJT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Nucleus

8128:LOC106098620
gene id: 8128:LOC106098620
uniprot id: A0A669BP33
names: Similarity
messages: Belongs to the cornifelin family.

8128:slc37a3
gene id: 8128:slc37a3
uniprot id: I3KIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8128:efnb2
gene id: 8128:efnb2
uniprot id: A0A669D1X6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:unc5c
gene id: 8128:unc5c
uniprot id: A0A669DEM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

8128:LOC100698564
gene id: 8128:LOC100698564
uniprot id: A0A669DBS8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8128:plcg1
gene id: 8128:plcg1
uniprot id: I3KLJ3
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

8128:dmap1
gene id: 8128:dmap1
uniprot id: I3J010
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100709052
gene id: 8128:LOC100709052
uniprot id: A0A669BZ25
uniprot id: I3IXW2
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8128:pomt2
gene id: 8128:pomt2
uniprot id: A0A669DR04
uniprot id: A0A669DT39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

8128:LOC100690141
gene id: 8128:LOC100690141
uniprot id: A0A669ELT3
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8128:lg10h11orf54
gene id: 8128:lg10h11orf54
uniprot id: A0A669CAQ0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

8128:cdk9
gene id: 8128:cdk9
uniprot id: I3K416
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100697931
gene id: 8128:LOC100697931
uniprot id: I3IYM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus

8128:stk11
gene id: 8128:stk11
uniprot id: A0A669BU24
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

8128:LOC100698114
gene id: 8128:LOC100698114
uniprot id: I3KL46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
messages: extracellular matrix

8128:abl2
gene id: 8128:abl2
uniprot id: A0A669D9Q2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:LOC100698415
gene id: 8128:LOC100698415
uniprot id: A0A669B2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus speckle

8128:LOC109203135
gene id: 8128:LOC109203135
uniprot id: I3JM36
names: Subcellular Location Annotation
messages: Secreted

8128:lzic
gene id: 8128:lzic
uniprot id: A0A669EXJ9
names: Similarity
messages: Belongs to the CTNNBIP1 family.

8128:LOC102082641
gene id: 8128:LOC102082641
uniprot id: A0A669BWS1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100706423
gene id: 8128:LOC100706423
uniprot id: A0A669DKV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline phosphatase family.
messages: Cell membrane
messages: Membrane

8128:ppp1r9a
gene id: 8128:ppp1r9a
uniprot id: A0A669B302
uniprot id: I3JXG1
names: Subcellular Location Annotation
messages: cytoskeleton

8128:LOC100694149
gene id: 8128:LOC100694149
uniprot id: I3K8D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm
messages: Nucleus

8128:isca2
gene id: 8128:isca2
uniprot id: A0A669DXY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

8128:LOC100708883
gene id: 8128:LOC100708883
uniprot id: I3JPX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

8128:LOC100699836
gene id: 8128:LOC100699836
uniprot id: I3JAP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8128:slc25a34
gene id: 8128:slc25a34
uniprot id: I3KRQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC100692133
gene id: 8128:LOC100692133
uniprot id: I3KJ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

8128:tprg1l
gene id: 8128:tprg1l
uniprot id: I3J198
names: Similarity
messages: Belongs to the TPRG1 family.

8128:LOC100699231
gene id: 8128:LOC100699231
uniprot id: A0A669CX62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:nipal2
gene id: 8128:nipal2
uniprot id: A0A669F4P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8128:LOC100695439
gene id: 8128:LOC100695439
uniprot id: I3J8K3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690369
gene id: 8128:LOC100690369
uniprot id: I3KT25
names: Similarity
messages: Belongs to the TTC39 family.

8128:LOC100709044
gene id: 8128:LOC100709044
uniprot id: I3JTR3
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8128:rab3il1
gene id: 8128:rab3il1
uniprot id: A0A669BJ72
uniprot id: I3KER4
names: Similarity
messages: Belongs to the SEC2 family.

8128:LOC106096846
gene id: 8128:LOC106096846
uniprot id: I3IUP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

8128:eml1
gene id: 8128:eml1
uniprot id: A0A669D4J8
names: Similarity
messages: Belongs to the WD repeat EMAP family.

8128:txnl4a
gene id: 8128:txnl4a
uniprot id: A0A669BPE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

8128:nsun4
gene id: 8128:nsun4
uniprot id: I3JWK4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

8128:LOC100695840
gene id: 8128:LOC100695840
uniprot id: I3KNF9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100708249
gene id: 8128:LOC100708249
uniprot id: A0A669DUR4
names: Similarity
messages: Belongs to the FAM20 family.

8128:fam228b
gene id: 8128:fam228b
uniprot id: A0A669CTB2
names: Similarity
messages: Belongs to the FAM228 family.

8128:pitx1
gene id: 8128:pitx1
uniprot id: A0A669EN61
uniprot id: A0A669EV09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

8128:zfpl1
gene id: 8128:zfpl1
uniprot id: I3IZY7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZFPL1 family.
messages: Membrane
messages: Required for cis-Golgi integrity and efficient ER to Golgi transport.
messages: The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.
messages: cis-Golgi network membrane

8128:scnm1
gene id: 8128:scnm1
uniprot id: I3JHQ7
names: Function
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.
messages: nucleoplasm

8128:tmem41b
gene id: 8128:tmem41b
uniprot id: A0A669AWB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

8128:kif7
gene id: 8128:kif7
uniprot id: I3JE56
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:LOC100701140
gene id: 8128:LOC100701140
uniprot id: A0A669B530
names: Similarity
messages: Belongs to the syntaxin family.

8128:LOC100709465
gene id: 8128:LOC100709465
uniprot id: I3J6P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

8128:evx1
gene id: 8128:evx1
uniprot id: A0A669E2P1
names: Subcellular Location Annotation
messages: Nucleus

8128:gldc
gene id: 8128:gldc
uniprot id: A0A669F0I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

8128:LOC100695684
gene id: 8128:LOC100695684
uniprot id: I3JJT5
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100712172
gene id: 8128:LOC100712172
uniprot id: I3J2A5
names: Subcellular Location Annotation
messages: extracellular space

8128:sox10
gene id: 8128:sox10
uniprot id: A0A669BRA5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100707066
gene id: 8128:LOC100707066
uniprot id: A0A669C0X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Lysosome
messages: cytosol
messages: extracellular exosome

8128:cenpm
gene id: 8128:cenpm
uniprot id: I3KNL5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100694258
gene id: 8128:LOC100694258
uniprot id: I3ITR4
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

8128:LOC100712167
gene id: 8128:LOC100712167
uniprot id: I3J8A3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:ppfibp1
gene id: 8128:ppfibp1
uniprot id: A0A669CLW0
uniprot id: A0A669CN11
uniprot id: I3KBF4
uniprot id: I3KBF5
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

8128:hhatl
gene id: 8128:hhatl
uniprot id: A0A669B060
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100710250
gene id: 8128:LOC100710250
uniprot id: A0A669DMM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:sfxn2
gene id: 8128:sfxn2
uniprot id: I3KFL6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

8128:mtmr10
gene id: 8128:mtmr10
uniprot id: I3JEU9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8128:LOC100700957
gene id: 8128:LOC100700957
uniprot id: I3JZK1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100707701
gene id: 8128:LOC100707701
uniprot id: I3IYF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100699661
gene id: 8128:LOC100699661
uniprot id: A0A669CAD7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8128:taf1
gene id: 8128:taf1
uniprot id: A0A669E2T9
uniprot id: I3J984
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

8128:LOC100699393
gene id: 8128:LOC100699393
uniprot id: I3J7U4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100701748
gene id: 8128:LOC100701748
uniprot id: A0A669CUB5
uniprot id: I3J0F2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100704478
gene id: 8128:LOC100704478
uniprot id: I3JAR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8128:slc37a1
gene id: 8128:slc37a1
uniprot id: A0A669BVK6
uniprot id: A0A669EA99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8128:LOC102079960
gene id: 8128:LOC102079960
uniprot id: I3J7D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8128:ate1
gene id: 8128:ate1
uniprot id: I3JVB2
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

8128:LOC100698230
gene id: 8128:LOC100698230
uniprot id: I3J7Y0
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC106097998
gene id: 8128:LOC106097998
uniprot id: A0A669DWI5
names: Similarity
messages: Belongs to the Bcl-2 family.

8128:dusp27
gene id: 8128:dusp27
uniprot id: I3J6V0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8128:LOC102081675
gene id: 8128:LOC102081675
uniprot id: A0A669CKR7
names: Function
messages: May be involved in neurite outgrowth.

8128:vps4a
gene id: 8128:vps4a
uniprot id: I3JY16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8128:LOC100691671
gene id: 8128:LOC100691671
uniprot id: I3J4B3
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

8128:LOC100711371
gene id: 8128:LOC100711371
uniprot id: I3JQM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane

8128:srm
gene id: 8128:srm
uniprot id: I3J212
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

8128:LOC100705410
gene id: 8128:LOC100705410
uniprot id: I3JPN0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:pusl1
gene id: 8128:pusl1
uniprot id: I3KTC2
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

8128:LOC100693502
gene id: 8128:LOC100693502
uniprot id: A0A669BQC0
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

8128:dse
gene id: 8128:dse
uniprot id: I3JZH3
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

8128:LOC100704961
gene id: 8128:LOC100704961
uniprot id: A0A669DRX1
names: Similarity
messages: Belongs to the MARCKS family.

8128:LOC100691978
gene id: 8128:LOC100691978
uniprot id: A0A669B6C0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8128:lama4
gene id: 8128:lama4
uniprot id: A0A669AXF3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:insm1
gene id: 8128:insm1
uniprot id: I3KZL3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC109198965
gene id: 8128:LOC109198965
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:pank4
gene id: 8128:pank4
uniprot id: I3IVW2
names: Similarity
names: Subunit
messages: Belongs to the type II pantothenate kinase family.
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.

8128:mtfp1
gene id: 8128:mtfp1
uniprot id: A0A669EW46
names: Similarity
messages: Belongs to the MTFP1 family.

8128:LOC100707847
gene id: 8128:LOC100707847
uniprot id: A0A669C9J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

8128:LOC100702271
gene id: 8128:LOC100702271
uniprot id: A0A669F4H5
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8128:LOC100693632
gene id: 8128:LOC100693632
uniprot id: I3K9W1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC102082249
gene id: 8128:LOC102082249
uniprot id: A0A669DS00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

8128:LOC100695063
gene id: 8128:LOC100695063
uniprot id: I3KBI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

8128:LOC100705541
gene id: 8128:LOC100705541
uniprot id: I3IWR3
names: Subcellular Location Annotation
messages: Nucleus

8128:rexo2
gene id: 8128:rexo2
uniprot id: A0A669DDC5
names: Similarity
messages: Belongs to the oligoribonuclease family.

8128:c8b
gene id: 8128:c8b
uniprot id: H2EP76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC102075509
gene id: 8128:LOC102075509
uniprot id: A0A669DZP2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC106096484
gene id: 8128:LOC106096484
uniprot id: I3JRP3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100691767
gene id: 8128:LOC100691767
uniprot id: A0A669F1S2
names: Similarity
messages: Belongs to the mTERF family.

8128:dpy19l4
gene id: 8128:dpy19l4
uniprot id: I3K8G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

8128:chst3
gene id: 8128:chst3
uniprot id: I3KGJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8128:sept6
gene id: 8128:sept6
uniprot id: A0A669CWC0
uniprot id: I3J2S5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8128:mcm3
gene id: 8128:mcm3
uniprot id: I3IYE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

8128:LOC100696335
gene id: 8128:LOC100696335
uniprot id: A0A669E5Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8128:LOC100697375
gene id: 8128:LOC100697375
uniprot id: I3J7N4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:gosr2
gene id: 8128:gosr2
uniprot id: A0A669B2S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

8128:LOC100704044
gene id: 8128:LOC100704044
uniprot id: I3KZP7
names: Subcellular Location Annotation
messages: Membrane

8128:adhfe1
gene id: 8128:adhfe1
uniprot id: I3IVJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

8128:lpl
gene id: 8128:lpl
uniprot id: E9K173
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

8128:LOC102082349
gene id: 8128:LOC102082349
uniprot id: A0A669CN57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8128:cxadr
gene id: 8128:cxadr
uniprot id: I3K8L0
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690803
gene id: 8128:LOC100690803
uniprot id: I3K1M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8128:cdk5rap1
gene id: 8128:cdk5rap1
uniprot id: I3KWM5
names: Similarity
messages: Belongs to the methylthiotransferase family. MiaB subfamily.

8128:LOC109203576
gene id: 8128:LOC109203576
uniprot id: A0A669BAN1
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

8128:eny2
gene id: 8128:eny2
uniprot id: A0A669BTC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

8128:LOC100695500
gene id: 8128:LOC100695500
uniprot id: A0A669BNU0
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100711993
gene id: 8128:LOC100711993
uniprot id: I3KD26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100701798
gene id: 8128:LOC100701798
uniprot id: A0A669BWI2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100697593
gene id: 8128:LOC100697593
uniprot id: A0A669CAK3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC100704516
gene id: 8128:LOC100704516
uniprot id: A0A669E723
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:vps18
gene id: 8128:vps18
uniprot id: I3IWH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

8128:LOC100697498
gene id: 8128:LOC100697498
uniprot id: I3KGP0
names: Similarity
messages: Belongs to the PPase family.

8128:cdc42ep4
gene id: 8128:cdc42ep4
uniprot id: I3KY92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8128:fto
gene id: 8128:fto
uniprot id: A0A669D0C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

8128:LOC100690330
gene id: 8128:LOC100690330
uniprot id: I3K166
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:pigm
gene id: 8128:pigm
uniprot id: I3KNE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

8128:LOC100701614
gene id: 8128:LOC100701614
uniprot id: A0A669AVQ8
uniprot id: I3J282
names: Subcellular Location Annotation
messages: extracellular space

8128:fignl1
gene id: 8128:fignl1
uniprot id: I3KZM4
names: Similarity
messages: Belongs to the AAA ATPase family.

8128:LOC100704341
gene id: 8128:LOC100704341
uniprot id: A0A669CBB7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100711982
gene id: 8128:LOC100711982
uniprot id: I3KIB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8128:LOC100697652
gene id: 8128:LOC100697652
uniprot id: I3KUG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:osbpl9
gene id: 8128:osbpl9
uniprot id: A0A669BCS2
uniprot id: I3J0T7
names: Similarity
messages: Belongs to the OSBP family.

8128:LOC100702338
gene id: 8128:LOC100702338
uniprot id: I3KCB3
names: Similarity
messages: Belongs to the PP2C family.

8128:LOC100711429
gene id: 8128:LOC100711429
uniprot id: I3KP96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:LOC100697226
gene id: 8128:LOC100697226
uniprot id: A0A669DRS6
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

8128:scube2
gene id: 8128:scube2
uniprot id: I3JFM9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:gal3st3
gene id: 8128:gal3st3
uniprot id: I3K5J3
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

8128:LOC100701803
gene id: 8128:LOC100701803
uniprot id: A0A669EMK0
uniprot id: I3K2Z9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:ipo5
gene id: 8128:ipo5
uniprot id: A0A669BZD0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100694684
gene id: 8128:LOC100694684
uniprot id: I3JFJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

8128:pmpcb
gene id: 8128:pmpcb
uniprot id: I3JMR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Mitochondrion matrix

8128:LOC100698949
gene id: 8128:LOC100698949
uniprot id: I3KP51
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8128:dnajc22
gene id: 8128:dnajc22
uniprot id: A0A669ERY5
names: Function
names: Subcellular Location Annotation
messages: May function as a co-chaperone.
messages: Membrane

8128:Mb
gene id: 8128:Mb
uniprot id: B9A9D4
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

8128:LOC100691498
gene id: 8128:LOC100691498
uniprot id: I3JW37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

8128:LOC100711270
gene id: 8128:LOC100711270
uniprot id: I3J173
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:tmem170a
gene id: 8128:tmem170a
uniprot id: A0A669C341
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

8128:tmem175
gene id: 8128:tmem175
uniprot id: A0A669C0Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

8128:LOC100699489
gene id: 8128:LOC100699489
uniprot id: I3JCB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

8128:sept5
gene id: 8128:sept5
uniprot id: A0A669DGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: cytoskeleton

8128:LOC100701299
gene id: 8128:LOC100701299
uniprot id: A0A669CQ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

8128:LOC100701165
gene id: 8128:LOC100701165
uniprot id: A0A669CMA1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:rpl18
gene id: 8128:rpl18
uniprot id: P69091
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
messages: Cytoplasm
messages: Rough endoplasmic reticulum
messages: cytosol

8128:LOC102075500
gene id: 8128:LOC102075500
uniprot id: A0A669BDL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8128:adck2
gene id: 8128:adck2
uniprot id: I3JQE0
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8128:LOC100701557
gene id: 8128:LOC100701557
uniprot id: I3KCU8
uniprot id: I3KCU9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100696682
gene id: 8128:LOC100696682
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:LOC100696848
gene id: 8128:LOC100696848
uniprot id: A0A669CZK4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100700733
gene id: 8128:LOC100700733
uniprot id: A0A669AVL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

8128:usp50
gene id: 8128:usp50
uniprot id: I3IUE7
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:hoxc11
gene id: 8128:hoxc11
uniprot id: I3K2R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8128:LOC100711125
gene id: 8128:LOC100711125
uniprot id: I3KFV6
names: Similarity
messages: Belongs to the peptidase M10A family.

8128:mapk6
gene id: 8128:mapk6
uniprot id: I3IUE3
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

8128:susd6
gene id: 8128:susd6
uniprot id: I3JEG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:tmem205
gene id: 8128:tmem205
uniprot id: I3JMN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

8128:mocs2
gene id: 8128:mocs2
uniprot id: I3K3S6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2A).
messages: cytosol

8128:LOC100700754
gene id: 8128:LOC100700754
uniprot id: I3JGA6
names: Similarity
messages: Belongs to the FAM98 family.

8128:LOC100694393
gene id: 8128:LOC100694393
uniprot id: I3JHB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

8128:LOC100702287
gene id: 8128:LOC100702287
uniprot id: I3KAJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

8128:arhgef7
gene id: 8128:arhgef7
uniprot id: A0A669DMF1
uniprot id: A0A669EH93
names: Subcellular Location Annotation
messages: lamellipodium

8128:LOC100706558
gene id: 8128:LOC100706558
uniprot id: I3KQQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

8128:LOC100707496
gene id: 8128:LOC100707496
uniprot id: A0A669BAC8
uniprot id: A0A669EAP4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:fnbp1l
gene id: 8128:fnbp1l
uniprot id: A0A669BH57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cytoplasmic vesicle
messages: Vesicle
messages: cell cortex

8128:slc35f6
gene id: 8128:slc35f6
uniprot id: A0A669ERQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

8128:ostc
gene id: 8128:ostc
uniprot id: A0A669C7W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8128:fyn
gene id: 8128:fyn
uniprot id: A0A669B9Z0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:LOC102082214
gene id: 8128:LOC102082214
uniprot id: A0A669EDA1
names: Similarity
messages: Belongs to the IUNH family.

8128:LOC100695940
gene id: 8128:LOC100695940
uniprot id: A0A669EYD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8128:LOC100699299
gene id: 8128:LOC100699299
uniprot id: A0A669EBK7
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100534433
gene id: 8128:LOC100534433
uniprot id: I3K7V7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8128:LOC100702538
gene id: 8128:LOC100702538
uniprot id: I3JN81
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8128:LOC100697873
gene id: 8128:LOC100697873
uniprot id: A0A669CQZ4
uniprot id: I3JGZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8128:LOC100694458
gene id: 8128:LOC100694458
uniprot id: A0A669DNV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

8128:LOC100712295
gene id: 8128:LOC100712295
uniprot id: A0A669DZA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

8128:atp6ap2
gene id: 8128:atp6ap2
uniprot id: I3JHX1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

8128:cdadc1
gene id: 8128:cdadc1
uniprot id: I3K2Z1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

8128:greb1l
gene id: 8128:greb1l
uniprot id: A0A669CRC9
uniprot id: I3JSI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

8128:LOC102083135
gene id: 8128:LOC102083135
uniprot id: I3KYX4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100709359
gene id: 8128:LOC100709359
uniprot id: I3JMB3
names: Similarity
messages: Belongs to the Rab GDI family.

8128:hoxa10
gene id: 8128:hoxa10
uniprot id: I3JA99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8128:LOC100534467
gene id: 8128:LOC100534467
uniprot id: A0A669CY43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8128:tlr2
gene id: 8128:tlr2
uniprot id: A0A669C9F0
uniprot id: I3KXS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

8128:LOC100696750
gene id: 8128:LOC100696750
uniprot id: A0A669EE94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

8128:prrx1
gene id: 8128:prrx1
uniprot id: I3JLZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8128:hsd11b2
gene id: 8128:hsd11b2
uniprot id: Q7ZZV0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100705080
gene id: 8128:LOC100705080
uniprot id: I3KHE9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690188
gene id: 8128:LOC100690188
uniprot id: I3JLF4
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

8128:LOC109204043
gene id: 8128:LOC109204043
uniprot id: I3ITW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8128:LOC100694190
gene id: 8128:LOC100694190
uniprot id: A0A669CXJ7
uniprot id: I3J7G4
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8128:tnfsf13b
gene id: 8128:tnfsf13b
uniprot id: I3KAB9
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8128:ampd1
gene id: 8128:ampd1
uniprot id: I3JS50
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

8128:phlda2
gene id: 8128:phlda2
uniprot id: I3KX98
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100694234
gene id: 8128:LOC100694234
uniprot id: A0A669DUE1
names: Similarity
messages: Belongs to the NDRG family.

8128:LOC100690751
gene id: 8128:LOC100690751
uniprot id: A0A669F5G8
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

8128:LOC100691077
gene id: 8128:LOC100691077
uniprot id: I3IYW5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:becn1
gene id: 8128:becn1
uniprot id: I3KHG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beclin family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Mitochondrion membrane
messages: Plays a central role in autophagy.
messages: autophagosome
messages: trans-Golgi network membrane

8128:LOC100701765
gene id: 8128:LOC100701765
uniprot id: A0A669CH53
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

8128:ralyl
gene id: 8128:ralyl
uniprot id: I3JGN9
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

8128:LOC100696184
gene id: 8128:LOC100696184
uniprot id: A0A669EV99
uniprot id: I3JPQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

8128:LOC100706186
gene id: 8128:LOC100706186
uniprot id: I3JJX0
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:tmx2
gene id: 8128:tmx2
uniprot id: I3JC13
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

8128:pigf
gene id: 8128:pigf
uniprot id: I3KFY6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:lbh
gene id: 8128:lbh
uniprot id: A0A669DNB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus

8128:aip
gene id: 8128:aip
uniprot id: I3KBB5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with RET in the pituitary gland; this interaction prevents the formation of the AIP-survivin complex.
messages: May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.

8128:LOC100696871
gene id: 8128:LOC100696871
uniprot id: I3KYB8
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

8128:lhfpl6
gene id: 8128:lhfpl6
uniprot id: I3JE73
names: Subcellular Location Annotation
messages: Membrane

8128:sdf4
gene id: 8128:sdf4
uniprot id: I3KIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

8128:LOC100695864
gene id: 8128:LOC100695864
uniprot id: I3JSV4
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:tasp1
gene id: 8128:tasp1
uniprot id: A0A669D6G8
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8128:LOC100699478
gene id: 8128:LOC100699478
uniprot id: A0A669FA01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Component of the cytosolic PAF-AH (I) heterotetrameric enzyme, which is composed of PAFAH1B1 (beta), PAFAH1B2 (alpha2) and PAFAH1B3 (alpha1) subunits. The catalytic activity of the enzyme resides in the alpha1 (PAFAH1B3) and alpha2 (PAFAH1B2) subunits, whereas the beta subunit (PAFAH1B1) has regulatory activity. Trimer formation is not essential for the catalytic activity (By similarity). Interacts with dynein, dynactin, nde1 and ndel1.
messages: Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
messages: centrosome
messages: cytoskeleton

8128:trpv4
gene id: 8128:trpv4
uniprot id: A0A669FAN2
names: Subcellular Location Annotation
messages: Membrane

8128:was
gene id: 8128:was
uniprot id: A0A669CQM5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100690430
gene id: 8128:LOC100690430
uniprot id: I3KVD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

8128:LOC100708550
gene id: 8128:LOC100708550
uniprot id: A0A669EMF0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:lypla1
gene id: 8128:lypla1
uniprot id: I3JFT3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

8128:mblac1
gene id: 8128:mblac1
uniprot id: I3IVW4
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8128:LOC100704787
gene id: 8128:LOC100704787
uniprot id: A0A669BLW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:LOC102077312
gene id: 8128:LOC102077312
uniprot id: I3KH75
names: Similarity
messages: Belongs to the NSG family.

8128:LOC109197509
gene id: 8128:LOC109197509
uniprot id: I3KI30
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100707664
gene id: 8128:LOC100707664
uniprot id: A0A669BFU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Postsynaptic density

8128:gclm
gene id: 8128:gclm
uniprot id: I3J254
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

8128:dnajc25
gene id: 8128:dnajc25
uniprot id: I3K499
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAJC25 family.
messages: Membrane

8128:pkm
gene id: 8128:pkm
uniprot id: A0A669CRW5
names: Similarity
messages: Belongs to the pyruvate kinase family.

8128:LOC100710763
gene id: 8128:LOC100710763
uniprot id: I3JX43
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

8128:mppe1
gene id: 8128:mppe1
uniprot id: A0A669B930
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallophosphoesterase superfamily. MPPE1 family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
messages: cis-Golgi network membrane

8128:dsp
gene id: 8128:dsp
uniprot id: I3JTG4
names: Subcellular Location Annotation
messages: cytoskeleton

8128:LOC100700608
gene id: 8128:LOC100700608
uniprot id: I3JWV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

8128:LOC100701210
gene id: 8128:LOC100701210
uniprot id: A0A669BJU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

8128:actl6a
gene id: 8128:actl6a
uniprot id: A0A669CTP7
names: Similarity
messages: Belongs to the actin family.

8128:LOC100695964
gene id: 8128:LOC100695964
uniprot id: A0A669EGT9
names: Similarity
messages: Belongs to the peptidase M10A family.

8128:LOC102077860
gene id: 8128:LOC102077860
uniprot id: I3K494
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100710319
gene id: 8128:LOC100710319
uniprot id: I3K2Y6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:LOC100710660
gene id: 8128:LOC100710660
uniprot id: I3JL49
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:usp32
gene id: 8128:usp32
uniprot id: A0A669F3S9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100712311
gene id: 8128:LOC100712311
uniprot id: A0A669F304
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100705741
gene id: 8128:LOC100705741
uniprot id: A0A669EG37
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8128:clstn2
gene id: 8128:clstn2
uniprot id: A0A669C917
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100701678
gene id: 8128:LOC100701678
uniprot id: I3IUH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

8128:bambi
gene id: 8128:bambi
uniprot id: I3J767
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BAMBI family.
messages: Membrane
messages: Negatively regulates TGF-beta signaling.

8128:LOC102081481
gene id: 8128:LOC102081481
uniprot id: I3J7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Cytoplasm
messages: Nucleus

8128:gria2
gene id: 8128:gria2
uniprot id: Q91226
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:LOC106096761
gene id: 8128:LOC106096761
uniprot id: I3KI27
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC102083201
gene id: 8128:LOC102083201
uniprot id: I3JQR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.
messages: extracellular space

8128:nmbr
gene id: 8128:nmbr
uniprot id: A0A669DL42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:pdia6
gene id: 8128:pdia6
uniprot id: A0A669EYI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

8128:KEH09 p10
gene id: 8128:KEH09_p10
uniprot id: D2KP27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100707394
gene id: 8128:LOC100707394
uniprot id: I3JGH5
names: Similarity
messages: Belongs to the GAB family.

8128:LOC100701261
gene id: 8128:LOC100701261
uniprot id: A0A669C0X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane

8128:clcn3
gene id: 8128:clcn3
uniprot id: A0A669E4R6
uniprot id: A0A669EJS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8128:LOC100712029
gene id: 8128:LOC100712029
uniprot id: I3K592
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8128:qsox1
gene id: 8128:qsox1
uniprot id: I3J0L8
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

8128:grm2
gene id: 8128:grm2
uniprot id: I3KS14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8128:sema6b
gene id: 8128:sema6b
uniprot id: A0A669DEI5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100700411
gene id: 8128:LOC100700411
uniprot id: I3K840
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC100704913
gene id: 8128:LOC100704913
uniprot id: I3J6P2
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8128:ddit4
gene id: 8128:ddit4
uniprot id: A0A669DL06
names: Similarity
messages: Belongs to the DDIT4 family.

8128:LOC100692673
gene id: 8128:LOC100692673
uniprot id: I3JMC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8128:gja5
gene id: 8128:gja5
uniprot id: I3KXX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:prdx5
gene id: 8128:prdx5
uniprot id: I3J024
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Peroxisome matrix
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

8128:rnaseh1
gene id: 8128:rnaseh1
uniprot id: I3KQZ3
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

8128:alkbh5
gene id: 8128:alkbh5
uniprot id: I3J547
names: Subcellular Location Annotation
names: Subunit
messages: Monomer.
messages: Nucleus speckle

8128:LOC100701794
gene id: 8128:LOC100701794
uniprot id: A0A669E0R1
names: Similarity
messages: Belongs to the PPP phosphatase family.

8128:pfn2
gene id: 8128:pfn2
uniprot id: A0A669DVI7
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

8128:noc3l
gene id: 8128:noc3l
uniprot id: A0A669F5I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: nucleolus

8128:prune1
gene id: 8128:prune1
uniprot id: I3IZ22
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

8128:prss12
gene id: 8128:prss12
uniprot id: I3KB66
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
messages: extracellular space

8128:oprd1
gene id: 8128:oprd1
uniprot id: A0A669BYP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100711153
gene id: 8128:LOC100711153
uniprot id: I3JIZ3
names: Similarity
messages: Belongs to the CARF family.

8128:LOC100699361
gene id: 8128:LOC100699361
uniprot id: I3J335
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100698181
gene id: 8128:LOC100698181
uniprot id: I3KZS4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:prkar2b
gene id: 8128:prkar2b
uniprot id: A0A669EVW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

8128:mfap3l
gene id: 8128:mfap3l
uniprot id: I3K5G5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100689957
gene id: 8128:LOC100689957
uniprot id: A0A669DDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:cyhr1
gene id: 8128:cyhr1
uniprot id: I3J200
names: Similarity
messages: Belongs to the ZFTRAF1 family.

8128:gmds
gene id: 8128:gmds
uniprot id: A0A669CEY9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

8128:itga4
gene id: 8128:itga4
uniprot id: A0A669BVM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:LOC100695194
gene id: 8128:LOC100695194
uniprot id: I3JHC9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8128:pdp1
gene id: 8128:pdp1
uniprot id: A0A669DX10
names: Similarity
messages: Belongs to the PP2C family.

8128:LOC100710281
gene id: 8128:LOC100710281
uniprot id: I3J016
names: Similarity
messages: Belongs to the PPP phosphatase family.

8128:b4gat1
gene id: 8128:b4gat1
uniprot id: I3K5I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:polr2k
gene id: 8128:polr2k
uniprot id: A0A669F840
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

8128:LOC100691484
gene id: 8128:LOC100691484
uniprot id: A0A669DY77
names: Subcellular Location Annotation
messages: Membrane

8128:ccnyl1
gene id: 8128:ccnyl1
uniprot id: I3KKB5
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin Y subfamily.

8128:sf3b4
gene id: 8128:sf3b4
uniprot id: I3J3I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

8128:LOC100693455
gene id: 8128:LOC100693455
uniprot id: I3JR48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100709580
gene id: 8128:LOC100709580
uniprot id: I3KYC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8128:LOC100700425
gene id: 8128:LOC100700425
uniprot id: I3JWP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

8128:tnk2
gene id: 8128:tnk2
uniprot id: A0A669CM30
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

8128:LOC100705576
gene id: 8128:LOC100705576
uniprot id: A0A669B120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

8128:LOC100706107
gene id: 8128:LOC100706107
uniprot id: A0A669CDZ1
names: Similarity
messages: Belongs to the RRM elav family.

8128:LOC100692385
gene id: 8128:LOC100692385
uniprot id: A0A669EL86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8128:cdk1
gene id: 8128:cdk1
uniprot id: I3JRM7
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100700932
gene id: 8128:LOC100700932
uniprot id: A0A669C820
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

8128:LOC100703276
gene id: 8128:LOC100703276
uniprot id: A0A669D667
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:hmgcl
gene id: 8128:hmgcl
uniprot id: I3JN26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

8128:hsp90b1
gene id: 8128:hsp90b1
uniprot id: A0A669BCF4
names: Similarity
messages: Belongs to the heat shock protein 90 family.

8128:LOC100689819
gene id: 8128:LOC100689819
uniprot id: I3JTG7
names: Similarity
messages: Belongs to the OSBP family.

8128:LOC100697854
gene id: 8128:LOC100697854
uniprot id: I3J076
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC109194541
gene id: 8128:LOC109194541
uniprot id: A0A669ELP6
names: Similarity
messages: Belongs to the DNase I family.

8128:LOC100694986
gene id: 8128:LOC100694986
uniprot id: I3JEK1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

8128:LOC100692108
gene id: 8128:LOC100692108
uniprot id: I3KGC0
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

8128:LOC100705812
gene id: 8128:LOC100705812
uniprot id: I3K000
names: Similarity
messages: Belongs to the ataxin-2 family.

8128:ndufab1
gene id: 8128:ndufab1
uniprot id: I3KF61
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

8128:LOC100711599
gene id: 8128:LOC100711599
uniprot id: A0A669E641
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100691236
gene id: 8128:LOC100691236
uniprot id: Q4VPV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8128:LOC100708293
gene id: 8128:LOC100708293
uniprot id: I3JXM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8128:plag1
gene id: 8128:plag1
uniprot id: I3JTD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

8128:LOC100690921
gene id: 8128:LOC100690921
uniprot id: I3K360
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:ufl1
gene id: 8128:ufl1
uniprot id: I3JZG7
names: Similarity
messages: Belongs to the UFL1 family.

8128:LOC100707476
gene id: 8128:LOC100707476
uniprot id: A0A669DCD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

8128:heatr5b
gene id: 8128:heatr5b
uniprot id: I3JUX7
names: Similarity
messages: Belongs to the HEATR5 family.

8128:LOC100703296
gene id: 8128:LOC100703296
uniprot id: A0A669DXQ8
names: Similarity
messages: Belongs to the NXPE family.

8128:polg2
gene id: 8128:polg2
uniprot id: A0A669E0D9
names: Subcellular Location Annotation
messages: Mitochondrion

8128:hspa4l
gene id: 8128:hspa4l
uniprot id: I3KW70
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8128:LOC100704978
gene id: 8128:LOC100704978
uniprot id: I3JCE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat coronin family.
messages: Cytoplasmic vesicle
messages: F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology.
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicle
messages: cytosol
messages: trans-Golgi network

8128:LOC100691407
gene id: 8128:LOC100691407
uniprot id: I3KDS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:sec22c
gene id: 8128:sec22c
uniprot id: A0A669D3V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

8128:LOC109201890
gene id: 8128:LOC109201890
uniprot id: A0A669DGW0
names: Similarity
messages: Belongs to the Bcl-2 family.

8128:stmn4
gene id: 8128:stmn4
uniprot id: I3IYE3
names: Similarity
messages: Belongs to the stathmin family.

8128:LOC100711611
gene id: 8128:LOC100711611
uniprot id: A0A669DBC4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:taf8
gene id: 8128:taf8
uniprot id: I3KI87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

8128:LOC100703334
gene id: 8128:LOC100703334
uniprot id: I3J793
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

8128:prph
gene id: 8128:prph
uniprot id: I3KSS6
names: Similarity
messages: Belongs to the intermediate filament family.

8128:LOC100697358
gene id: 8128:LOC100697358
uniprot id: I3JHY8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

8128:tmeff1
gene id: 8128:tmeff1
uniprot id: A0A669CXF0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100704482
gene id: 8128:LOC100704482
uniprot id: A0A669BAM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8128:LOC100702880
gene id: 8128:LOC100702880
uniprot id: A0A669EH02
names: Subcellular Location Annotation
messages: Nucleus

8128:ccdc130
gene id: 8128:ccdc130
uniprot id: A0A669CR38
names: Similarity
messages: Belongs to the CWC16 family.

8128:vps36
gene id: 8128:vps36
uniprot id: I3JAW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

8128:LOC100699530
gene id: 8128:LOC100699530
uniprot id: A0A669B1M0
names: Subcellular Location Annotation
messages: Membrane

8128:tfap2d
gene id: 8128:tfap2d
uniprot id: I3JDU7
names: Similarity
messages: Belongs to the AP-2 family.

8128:LOC100697316
gene id: 8128:LOC100697316
uniprot id: A0A669E4V0
names: Similarity
messages: Belongs to the cystatin family.

8128:LOC100691213
gene id: 8128:LOC100691213
uniprot id: I3KCI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse

8128:LOC100703448
gene id: 8128:LOC100703448
uniprot id: A0A669EV55
names: Subcellular Location Annotation
messages: Membrane

8128:pax5
gene id: 8128:pax5
uniprot id: I3JQV8
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100712257
gene id: 8128:LOC100712257
uniprot id: I3J406
names: Similarity
messages: Belongs to the OSBP family.

8128:LOC100695310
gene id: 8128:LOC100695310
uniprot id: I3JRN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:vsig10l
gene id: 8128:vsig10l
uniprot id: A0A669BS17
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100691827
gene id: 8128:LOC100691827
uniprot id: A0A669CTS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

8128:haus1
gene id: 8128:haus1
uniprot id: I3JAJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

8128:yipf5
gene id: 8128:yipf5
uniprot id: A0A669BM65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

8128:LOC100701996
gene id: 8128:LOC100701996
uniprot id: I3J752
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:senp7
gene id: 8128:senp7
uniprot id: A0A669CE83
names: Similarity
messages: Belongs to the peptidase C48 family.

8128:hddc2
gene id: 8128:hddc2
uniprot id: I3IW59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

8128:LOC100699987
gene id: 8128:LOC100699987
uniprot id: I3JGT7
names: Similarity
messages: Belongs to the SELO family.

8128:LOC100696271
gene id: 8128:LOC100696271
uniprot id: A0A669EGF5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

8128:LOC100703463
gene id: 8128:LOC100703463
uniprot id: I3KQN0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8128:LOC100698247
gene id: 8128:LOC100698247
uniprot id: I3KQZ1
names: Similarity
messages: Belongs to the GORASP family.

8128:LOC106098523
gene id: 8128:LOC106098523
uniprot id: I3KVL0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:LOC100701109
gene id: 8128:LOC100701109
uniprot id: I3KFM0
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8128:LOC100705749
gene id: 8128:LOC100705749
uniprot id: I3JPV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: Endomembrane system
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: clathrin-coated pit
messages: cytosol
messages: synaptic vesicle membrane

8128:LOC100708030
gene id: 8128:LOC100708030
uniprot id: A0A669C7C5
names: Similarity
messages: Belongs to the TGF-beta family.

8128:LOC100695043
gene id: 8128:LOC100695043
uniprot id: I3JRM9
uniprot id: I3JRN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:slc37a4
gene id: 8128:slc37a4
uniprot id: I3JD84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8128:sept10
gene id: 8128:sept10
uniprot id: A0A669D8W1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8128:LOC100700197
gene id: 8128:LOC100700197
uniprot id: A0A669CH89
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:bag6
gene id: 8128:bag6
uniprot id: A0A669B696
names: Subcellular Location Annotation
messages: Nucleus
messages: extracellular exosome

8128:LOC100690431
gene id: 8128:LOC100690431
uniprot id: A0A669BD49
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:LOC100709764
gene id: 8128:LOC100709764
uniprot id: A0A669CJ37
uniprot id: A0A669E7F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

8128:c1qbp
gene id: 8128:c1qbp
uniprot id: I3KLP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

8128:sec24d
gene id: 8128:sec24d
uniprot id: I3JL58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8128:LOC100709697
gene id: 8128:LOC100709697
uniprot id: I3JUD1
names: Similarity
messages: Belongs to the DENND11 family.

8128:LOC100692112
gene id: 8128:LOC100692112
uniprot id: A0A669BJU9
names: Similarity
messages: Belongs to the PIAS family.

8128:LOC100707214
gene id: 8128:LOC100707214
uniprot id: I3KRC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: desmosome

8128:LOC100707934
gene id: 8128:LOC100707934
uniprot id: A0A669CLC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8128:LOC100697024
gene id: 8128:LOC100697024
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:LOC100690212
gene id: 8128:LOC100690212
uniprot id: A0A669BIS1
names: Similarity
messages: Belongs to the NDRG family.

8128:LOC102079339
gene id: 8128:LOC102079339
uniprot id: A0A669E777
uniprot id: I3KGK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

8128:kcnk2
gene id: 8128:kcnk2
uniprot id: I3K7C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:LOC100706474
gene id: 8128:LOC100706474
uniprot id: I3KM71
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100692426
gene id: 8128:LOC100692426
uniprot id: A0A669F069
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8128:LOC100699967
gene id: 8128:LOC100699967
uniprot id: A0A669EJC8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100693638
gene id: 8128:LOC100693638
uniprot id: I3KW38
names: Similarity
messages: Belongs to the peptidase S1C family.

8128:LOC100705436
gene id: 8128:LOC100705436
uniprot id: A0A669CS32
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

8128:LOC100701914
gene id: 8128:LOC100701914
uniprot id: I3JGF5
names: Similarity
messages: Belongs to the MAGUK family.

8128:pxmp2
gene id: 8128:pxmp2
uniprot id: I3K705
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

8128:LOC100697387
gene id: 8128:LOC100697387
uniprot id: I3KVL0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:LOC100694118
gene id: 8128:LOC100694118
uniprot id: A0A669F556
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:capn3
gene id: 8128:capn3
uniprot id: I3IV72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

8128:atg4c
gene id: 8128:atg4c
uniprot id: I3JQF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8128:LOC100698988
gene id: 8128:LOC100698988
uniprot id: A0A669EJB8
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100693040
gene id: 8128:LOC100693040
uniprot id: A0A669C2P3
uniprot id: I3JMY6
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

8128:LOC100706920
gene id: 8128:LOC100706920
uniprot id: A0A669C8G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

8128:entpd3
gene id: 8128:entpd3
uniprot id: I3JJJ2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8128:LOC100692957
gene id: 8128:LOC100692957
uniprot id: A0A669BX45
names: Subcellular Location Annotation
messages: Membrane

8128:ptprd
gene id: 8128:ptprd
uniprot id: A0A669F3N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
messages: Membrane

8128:LOC100690299
gene id: 8128:LOC100690299
uniprot id: A0A669D6S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

8128:LOC100694928
gene id: 8128:LOC100694928
uniprot id: A0A669AYB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

8128:tmem177
gene id: 8128:tmem177
uniprot id: I3J9Q8
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

8128:LOC100699202
gene id: 8128:LOC100699202
uniprot id: I3KCL4
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC106097720
gene id: 8128:LOC106097720
uniprot id: A0A669BNR8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:ldlrad3
gene id: 8128:ldlrad3
uniprot id: A0A669CTF2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100702192
gene id: 8128:LOC100702192
uniprot id: A0A669CG92
uniprot id: I3KPD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8128:cndp2
gene id: 8128:cndp2
uniprot id: Q3LFW5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

8128:LOC100705213
gene id: 8128:LOC100705213
uniprot id: I3JRV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:LOC100704678
gene id: 8128:LOC100704678
uniprot id: A0A669AYS1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8128:LOC100697749
gene id: 8128:LOC100697749
uniprot id: A0A669DKW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:eif2s1
gene id: 8128:eif2s1
uniprot id: I3JF24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

8128:sppl3
gene id: 8128:sppl3
uniprot id: A0A669BLW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

8128:LOC100701228
gene id: 8128:LOC100701228
uniprot id: I3IWD1
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

8128:LOC109197403
gene id: 8128:LOC109197403
uniprot id: A0A669AX56
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100702850
gene id: 8128:LOC100702850
uniprot id: I3IVI9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

8128:pde7a
gene id: 8128:pde7a
uniprot id: A0A669BSS8
uniprot id: A0A669CRE2
uniprot id: A0A669EZ94
uniprot id: A0A669F2D5
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC100712094
gene id: 8128:LOC100712094
uniprot id: I3KAM8
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8128:LOC100699230
gene id: 8128:LOC100699230
uniprot id: I3KBP0
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100712479
gene id: 8128:LOC100712479
uniprot id: A0A669C707
names: Similarity
messages: Belongs to the serpin family.

8128:rps25
gene id: 8128:rps25
uniprot id: A0A669E4L2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

8128:nob1
gene id: 8128:nob1
uniprot id: A0A669BG61
uniprot id: I3J5N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: May play a role in mRNA degradation.
messages: Nucleus

8128:nubp2
gene id: 8128:nubp2
uniprot id: I3KVS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

8128:fbxo45
gene id: 8128:fbxo45
uniprot id: A0A669DQX4
names: Similarity
messages: Belongs to the FBXO45/Fsn family.

8128:sntg1
gene id: 8128:sntg1
uniprot id: I3JSY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

8128:tmem33
gene id: 8128:tmem33
uniprot id: I3IYN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

8128:LOC100698694
gene id: 8128:LOC100698694
uniprot id: I3KGQ8
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100534411
gene id: 8128:LOC100534411
uniprot id: I3ITZ0
names: Similarity
messages: Belongs to the actin family.

8128:LOC100689713
gene id: 8128:LOC100689713
uniprot id: A0A669BMW1
uniprot id: I3KKP2
names: Subcellular Location Annotation
messages: cytoskeleton

8128:cdc42ep3
gene id: 8128:cdc42ep3
uniprot id: A0A669E5T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8128:LOC100703770
gene id: 8128:LOC100703770
uniprot id: A0A669BD67
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

8128:fat4
gene id: 8128:fat4
uniprot id: I3IYW2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:cdk4
gene id: 8128:cdk4
uniprot id: I3KSQ0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:stat3
gene id: 8128:stat3
uniprot id: A0A669B7P3
uniprot id: I3IXW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8128:gss
gene id: 8128:gss
uniprot id: A0A669CFS7
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

8128:LOC100691884
gene id: 8128:LOC100691884
uniprot id: A0A669BNF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8128:LOC100706119
gene id: 8128:LOC100706119
uniprot id: I3KBF1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100695167
gene id: 8128:LOC100695167
uniprot id: I3KMF8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:cops4
gene id: 8128:cops4
uniprot id: I3KE36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

8128:nup93
gene id: 8128:nup93
uniprot id: A0A669D922
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

8128:LOC100705046
gene id: 8128:LOC100705046
uniprot id: A0A669CTP1
names: Similarity
messages: Belongs to the peptidase S8 family.

8128:pmp22
gene id: 8128:pmp22
uniprot id: I3JMF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

8128:LOC100696877
gene id: 8128:LOC100696877
uniprot id: I3KYF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:tmem18
gene id: 8128:tmem18
uniprot id: A0A669DVD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

8128:tenm3
gene id: 8128:tenm3
uniprot id: A0A669BMJ8
uniprot id: A0A669BWT4
uniprot id: A0A669C1P2
uniprot id: A0A669C3H6
uniprot id: A0A669C4M1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100708007
gene id: 8128:LOC100708007
uniprot id: I3JAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8128:prlr2
gene id: 8128:prlr2
uniprot id: B1NA45
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

8128:prpf4
gene id: 8128:prpf4
uniprot id: I3K4A2
names: Subcellular Location Annotation
messages: Nucleus speckle

8128:LOC100692546
gene id: 8128:LOC100692546
uniprot id: I3JHI8
names: Function
names: Similarity
names: Subunit
messages: Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.
messages: Belongs to the fucolectin family.
messages: Homotrimer.

8128:LOC100697579
gene id: 8128:LOC100697579
uniprot id: I3JEH6
names: Similarity
messages: Belongs to the cystatin family.

8128:LOC100697109
gene id: 8128:LOC100697109
uniprot id: A0A669EU62
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

8128:mrpl10
gene id: 8128:mrpl10
uniprot id: A0A669CQ62
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

8128:LOC100691587
gene id: 8128:LOC100691587
uniprot id: I3JJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100707618
gene id: 8128:LOC100707618
uniprot id: A0A669BRY0
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100699458
gene id: 8128:LOC100699458
uniprot id: I3IX89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

8128:ctbs
gene id: 8128:ctbs
uniprot id: A0A669BT36
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

8128:LOC100695530
gene id: 8128:LOC100695530
uniprot id: I3KJ31
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

8128:scn3b
gene id: 8128:scn3b
uniprot id: I3JFX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

8128:LOC100704395
gene id: 8128:LOC100704395
uniprot id: A0A669CKH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

8128:erlec1
gene id: 8128:erlec1
uniprot id: A0A669D670
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

8128:epha10
gene id: 8128:epha10
uniprot id: I3K7K0
names: Subcellular Location Annotation
messages: Cell membrane

8128:LOC102083175
gene id: 8128:LOC102083175
uniprot id: I3J1B7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100692521
gene id: 8128:LOC100692521
uniprot id: I3JNK1
names: Similarity
messages: Belongs to the TMEM178 family.

8128:cfap300
gene id: 8128:cfap300
uniprot id: I3J292
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

8128:chst1
gene id: 8128:chst1
uniprot id: I3KXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8128:sgcb
gene id: 8128:sgcb
uniprot id: I3J4L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The association between SGCB and SGCG is particularly strong while SGCA is loosely associated with the other sarcoglycans.
messages: cytoskeleton
messages: sarcolemma

8128:LOC100690133
gene id: 8128:LOC100690133
uniprot id: A0A669EMR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:LOC100695624
gene id: 8128:LOC100695624
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:ebna1bp2
gene id: 8128:ebna1bp2
uniprot id: A0A669E9N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: Required for the processing of the 27S pre-rRNA.
messages: nucleolus

8128:specc1l
gene id: 8128:specc1l
uniprot id: I3KG22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

8128:LOC100706449
gene id: 8128:LOC100706449
uniprot id: A0A669F7C0
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

8128:lrwd1
gene id: 8128:lrwd1
uniprot id: I3JSP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

8128:LOC100697937
gene id: 8128:LOC100697937
uniprot id: I3JPJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

8128:LOC100700835
gene id: 8128:LOC100700835
uniprot id: A0A669EG14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC106098252
gene id: 8128:LOC106098252
uniprot id: A0A669E3L1
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

8128:hus1
gene id: 8128:hus1
uniprot id: I3K6T5
names: Similarity
messages: Belongs to the HUS1 family.

8128:setd2
gene id: 8128:setd2
uniprot id: A0A669D011
uniprot id: I3J4R5
names: Subcellular Location Annotation
messages: Nucleus

8128:ptgir
gene id: 8128:ptgir
uniprot id: I3JF84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:atp5mc3
gene id: 8128:atp5mc3
uniprot id: I3JPP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

8128:LOC106096996
gene id: 8128:LOC106096996
uniprot id: A0A669B869
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8128:LOC100698978
gene id: 8128:LOC100698978
uniprot id: I3KP06
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

8128:wasf1
gene id: 8128:wasf1
uniprot id: A0A669CLI9
uniprot id: I3K704
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8128:aplp1
gene id: 8128:aplp1
uniprot id: A0A669C4X9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100709239
gene id: 8128:LOC100709239
uniprot id: I3J388
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

8128:LOC100704490
gene id: 8128:LOC100704490
uniprot id: A0A669CYM9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

8128:LOC100703116
gene id: 8128:LOC100703116
uniprot id: I3JR09
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC109202906
gene id: 8128:LOC109202906
uniprot id: A0A669DIN4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC106098924
gene id: 8128:LOC106098924
uniprot id: A0A669D632
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100691685
gene id: 8128:LOC100691685
uniprot id: I3KKU2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNF168 family.
messages: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).

8128:mterf2
gene id: 8128:mterf2
uniprot id: I3KZP1
names: Similarity
messages: Belongs to the mTERF family.

8128:tm9sf4
gene id: 8128:tm9sf4
uniprot id: I3IVF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

8128:LOC100696293
gene id: 8128:LOC100696293
uniprot id: A0A669EVJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:cpvl
gene id: 8128:cpvl
uniprot id: A0A669F4P3
names: Similarity
messages: Belongs to the peptidase S10 family.

8128:senp6
gene id: 8128:senp6
uniprot id: I3KR54
names: Similarity
messages: Belongs to the peptidase C48 family.

8128:pgls
gene id: 8128:pgls
uniprot id: I3J0J1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

8128:agtrap
gene id: 8128:agtrap
uniprot id: A0A669EZR1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100698922
gene id: 8128:LOC100698922
uniprot id: I3J201
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100709663
gene id: 8128:LOC100709663
uniprot id: A0A669CUR1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:LOC100693087
gene id: 8128:LOC100693087
uniprot id: I3KNS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8128:LOC102079681
gene id: 8128:LOC102079681
uniprot id: A0A669CW58
names: Subcellular Location Annotation
messages: Membrane

8128:ins
gene id: 8128:ins
uniprot id: I3IUZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

8128:LOC100707393
gene id: 8128:LOC100707393
uniprot id: A0A669BQT0
names: Similarity
messages: Belongs to the DeSI family.

8128:LOC100700119
gene id: 8128:LOC100700119
uniprot id: A0A669B3V0
names: Similarity
messages: Belongs to the intermediate filament family.

8128:nde1
gene id: 8128:nde1
uniprot id: I3KRL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

8128:usp30
gene id: 8128:usp30
uniprot id: A0A669EQQ6
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:tns3
gene id: 8128:tns3
uniprot id: I3JTF7
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8128:e2f7
gene id: 8128:e2f7
uniprot id: I3K247
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8128:LOC100702483
gene id: 8128:LOC100702483
uniprot id: I3KKG7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100703799
gene id: 8128:LOC100703799
uniprot id: A0A669EST5
names: Similarity
messages: Belongs to the taxilin family.

8128:nup133
gene id: 8128:nup133
uniprot id: A0A669E683
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

8128:LOC100711208
gene id: 8128:LOC100711208
uniprot id: I3K2G4
names: Similarity
messages: Belongs to the peptidase M24 family.

8128:LOC100698459
gene id: 8128:LOC100698459
uniprot id: I3JYT1
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

8128:LOC100712317
gene id: 8128:LOC100712317
uniprot id: I3KKH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:ncapd2
gene id: 8128:ncapd2
uniprot id: I3K540
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

8128:LOC100710187
gene id: 8128:LOC100710187
uniprot id: I3L063
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:erc1
gene id: 8128:erc1
uniprot id: A0A669B3P4
uniprot id: A0A669CRN1
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100702846
gene id: 8128:LOC100702846
uniprot id: A0A669CYS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8128:LOC100708824
gene id: 8128:LOC100708824
uniprot id: A0A669CZU9
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

8128:LOC100694765
gene id: 8128:LOC100694765
uniprot id: I3IYQ8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:LOC100694968
gene id: 8128:LOC100694968
uniprot id: I3JQP5
names: Similarity
messages: Belongs to the GPSM family.

8128:LOC100702539
gene id: 8128:LOC100702539
uniprot id: I3JDN6
uniprot id: I3JDN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

8128:LOC100700080
gene id: 8128:LOC100700080
uniprot id: I3KTB8
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100700045
gene id: 8128:LOC100700045
uniprot id: I3KEX1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

8128:lg3h20orf27
gene id: 8128:lg3h20orf27
uniprot id: A0A669BHW5
names: Similarity
messages: Belongs to the UPF0687 family.

8128:LOC100708651
gene id: 8128:LOC100708651
uniprot id: I3JJ34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

8128:tnfrsf19
gene id: 8128:tnfrsf19
uniprot id: I3JDA2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:dmrt2b
gene id: 8128:dmrt2b
uniprot id: Q6XYR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

8128:tceanc2
gene id: 8128:tceanc2
uniprot id: A0A669ERQ5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100706118
gene id: 8128:LOC100706118
uniprot id: I3J8M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8128:LOC100699176
gene id: 8128:LOC100699176
uniprot id: I3JVJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:LOC100710552
gene id: 8128:LOC100710552
uniprot id: I3JGN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8128:LOC100710359
gene id: 8128:LOC100710359
uniprot id: I3KGL2
names: Similarity
messages: Belongs to the ARS2 family.

8128:dusp6
gene id: 8128:dusp6
uniprot id: I3J7Q0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8128:pc
gene id: 8128:pc
uniprot id: I3K759
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

8128:rtn1
gene id: 8128:rtn1
uniprot id: A0A669ECE7
uniprot id: I3KW57
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:btg1
gene id: 8128:btg1
uniprot id: A0A669DSX4
names: Function
names: Similarity
messages: Anti-proliferative protein.
messages: Belongs to the BTG family.

8128:LOC100700376
gene id: 8128:LOC100700376
uniprot id: A0A669CX23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: nucleolus

8128:mrpl19
gene id: 8128:mrpl19
uniprot id: I3KBQ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

8128:irak1bp1
gene id: 8128:irak1bp1
uniprot id: I3IXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100707941
gene id: 8128:LOC100707941
uniprot id: A0A669EQ29
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100703294
gene id: 8128:LOC100703294
uniprot id: I3JJD0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100690518
gene id: 8128:LOC100690518
uniprot id: I3KJ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:fnip1
gene id: 8128:fnip1
uniprot id: A0A669DB14
uniprot id: I3KKU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

8128:smad9
gene id: 8128:smad9
uniprot id: I3K431
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100700731
gene id: 8128:LOC100700731
uniprot id: I3K9D4
names: Similarity
messages: Belongs to the peptidase M67C family.

8128:LOC100700383
gene id: 8128:LOC100700383
uniprot id: A0A669CRH0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neuromodulin family.
messages: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
messages: Cell membrane
messages: Membrane
messages: Palmitoylated. Palmitoylation is essential for plasma membrane association.
messages: Synapse
messages: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
messages: filopodium membrane
messages: growth cone membrane

8128:pus3
gene id: 8128:pus3
uniprot id: I3KH33
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

8128:aoc1
gene id: 8128:aoc1
uniprot id: I3JZ57
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

8128:cetp
gene id: 8128:cetp
uniprot id: A0A669E7A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL.
messages: Secreted

8128:nup188
gene id: 8128:nup188
uniprot id: I3JKC2
names: Subcellular Location Annotation
messages: nuclear pore complex

8128:LOC100709876
gene id: 8128:LOC100709876
uniprot id: I3JN06
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100704093
gene id: 8128:LOC100704093
uniprot id: I3KXB0
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100696613
gene id: 8128:LOC100696613
uniprot id: I3J6G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8128:LOC100697996
gene id: 8128:LOC100697996
uniprot id: A0A669AZ39
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:zbtb8os
gene id: 8128:zbtb8os
uniprot id: I3K2Q3
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

8128:ankrd13d
gene id: 8128:ankrd13d
uniprot id: A0A669F895
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

8128:LOC100694645
gene id: 8128:LOC100694645
uniprot id: I3JTF3
names: Cofactor
messages: Binds 2 iron ions per subunit.

8128:cab39
gene id: 8128:cab39
uniprot id: I3JMB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

8128:fstl4
gene id: 8128:fstl4
uniprot id: A0A669AXK2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100704860
gene id: 8128:LOC100704860
uniprot id: I3K1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

8128:LOC100696765
gene id: 8128:LOC100696765
uniprot id: I3KP63
names: Similarity
messages: Belongs to the MHC class I family.

8128:LOC100700220
gene id: 8128:LOC100700220
uniprot id: I3K6P4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100700253
gene id: 8128:LOC100700253
uniprot id: A0A669DKL4
names: Similarity
messages: Belongs to the TAFA family.

8128:LOC100700506
gene id: 8128:LOC100700506
uniprot id: A0A669DN35
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:gprc5b
gene id: 8128:gprc5b
uniprot id: I3KKE2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100706012
gene id: 8128:LOC100706012
uniprot id: I3JD75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

8128:LOC102083013
gene id: 8128:LOC102083013
uniprot id: A0A669C0I3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:pex5
gene id: 8128:pex5
uniprot id: A0A669DLL8
uniprot id: A0A669F199
uniprot id: I3K5E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
messages: Cytoplasm
messages: Membrane

8128:glrx
gene id: 8128:glrx
uniprot id: A0A669DPR4
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

8128:myo1e
gene id: 8128:myo1e
uniprot id: A0A669BI99
uniprot id: I3JES6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:slc39a12
gene id: 8128:slc39a12
uniprot id: I3JFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

8128:polr2d
gene id: 8128:polr2d
uniprot id: I3KL11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

8128:mmgt1
gene id: 8128:mmgt1
uniprot id: A0A669DEX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

8128:LOC100709853
gene id: 8128:LOC100709853
uniprot id: A0A669BAR4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8128:LOC102078110
gene id: 8128:LOC102078110
uniprot id: A0A669CQ37
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

8128:smarcd1
gene id: 8128:smarcd1
uniprot id: A0A669CBK8
names: Similarity
messages: Belongs to the SMARCD family.

8128:LOC102079417
gene id: 8128:LOC102079417
uniprot id: I3KR61
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100692541
gene id: 8128:LOC100692541
uniprot id: I3KGP4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100696505
gene id: 8128:LOC100696505
uniprot id: A0A669BES1
names: Subcellular Location Annotation
messages: Nucleus

8128:polr2h
gene id: 8128:polr2h
uniprot id: A0A669DF46
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

8128:LOC100689712
gene id: 8128:LOC100689712
uniprot id: A0A669EB19
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:zc3h12b
gene id: 8128:zc3h12b
uniprot id: I3K4Z6
names: Similarity
messages: Belongs to the ZC3H12 family.

8128:slc25a19
gene id: 8128:slc25a19
uniprot id: I3J1S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC100708890
gene id: 8128:LOC100708890
uniprot id: A0A669CDV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:btd
gene id: 8128:btd
uniprot id: I3JXQ1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

8128:fuca2
gene id: 8128:fuca2
uniprot id: I3IVT2
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

8128:tmem173
gene id: 8128:tmem173
uniprot id: A0A4P8NPQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: autophagosome membrane
messages: perinuclear region

8128:adgrb3
gene id: 8128:adgrb3
uniprot id: I3JTS3
names: Subcellular Location Annotation
messages: Membrane

8128:rpl21
gene id: 8128:rpl21
uniprot id: I3K9H1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

8128:LOC102082138
gene id: 8128:LOC102082138
uniprot id: I3J7L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8128:eno2
gene id: 8128:eno2
uniprot id: A0A669DUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

8128:LOC100705406
gene id: 8128:LOC100705406
uniprot id: A0A669BFG5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:capg
gene id: 8128:capg
uniprot id: I3KRY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
messages: Cytoplasm
messages: Melanosome
messages: Nucleus
messages: lamellipodium
messages: ruffle

8128:LOC100707734
gene id: 8128:LOC100707734
uniprot id: I3J8N5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8128:LOC100698635
gene id: 8128:LOC100698635
uniprot id: I3J2K5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:granulin
gene id: 8128:granulin
uniprot id: C7E2T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8128:grk3
gene id: 8128:grk3
uniprot id: I3JZR4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8128:tspan33
gene id: 8128:tspan33
uniprot id: A0A669C430
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100707274
gene id: 8128:LOC100707274
uniprot id: A0A669CIM1
names: Similarity
messages: Belongs to the LEM family.

8128:prdm5
gene id: 8128:prdm5
uniprot id: A0A669DFG6
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100692643
gene id: 8128:LOC100692643
uniprot id: I3JM63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LZTS2 family.
messages: Cytoplasm
messages: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
messages: centrosome

8128:prpf18
gene id: 8128:prpf18
uniprot id: A0A669EIU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

8128:LOC100701417
gene id: 8128:LOC100701417
uniprot id: A0A669CXS2
uniprot id: A0A669EDG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: centrosome

8128:LOC106097129
gene id: 8128:LOC106097129
uniprot id: A0A669DJI9
names: Similarity
messages: Belongs to the FAM110 family.

8128:LOC100703384
gene id: 8128:LOC100703384
uniprot id: A0A669B084
uniprot id: A0A669EUH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

8128:LOC100712075
gene id: 8128:LOC100712075
uniprot id: A0A669CKV8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

8128:dhdds
gene id: 8128:dhdds
uniprot id: A0A669EJ01
uniprot id: I3KHI0
names: Similarity
messages: Belongs to the UPP synthase family.

8128:LOC100709936
gene id: 8128:LOC100709936
uniprot id: I3JGV0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

8128:LOC100690808
gene id: 8128:LOC100690808
uniprot id: A0A669BBQ6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:ucn
gene id: 8128:ucn
uniprot id: I3KZQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

8128:pgs1
gene id: 8128:pgs1
uniprot id: A0A669BYS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

8128:tvp23b
gene id: 8128:tvp23b
uniprot id: I3KNT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

8128:LOC100701743
gene id: 8128:LOC100701743
uniprot id: I3KIK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8128:LOC100699687
gene id: 8128:LOC100699687
uniprot id: A0A669BUY8
names: Similarity
messages: Belongs to the intermediate filament family.

8128:smpd2
gene id: 8128:smpd2
uniprot id: I3KBL2
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

8128:prkaca
gene id: 8128:prkaca
uniprot id: I3KHS3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

8128:htr2b
gene id: 8128:htr2b
uniprot id: A0A669C8P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

8128:LOC100699239
gene id: 8128:LOC100699239
uniprot id: I3IZL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:LOC100701059
gene id: 8128:LOC100701059
uniprot id: I3L037
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100704623
gene id: 8128:LOC100704623
uniprot id: A0A669BHL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:aars2
gene id: 8128:aars2
uniprot id: I3JK62
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

8128:pygl
gene id: 8128:pygl
uniprot id: A0A669ERP4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

8128:LOC100697201
gene id: 8128:LOC100697201
uniprot id: A0A669E6Y8
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8128:tmco3
gene id: 8128:tmco3
uniprot id: I3J555
names: Subcellular Location Annotation
messages: Membrane

8128:mtif3
gene id: 8128:mtif3
uniprot id: I3JE24
names: Similarity
messages: Belongs to the IF-3 family.

8128:LOC100699273
gene id: 8128:LOC100699273
uniprot id: I3IU30
names: Subcellular Location Annotation
messages: Membrane

8128:adgrl4
gene id: 8128:adgrl4
uniprot id: I3J3B7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100693308
gene id: 8128:LOC100693308
uniprot id: I3JS76
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:cstf1
gene id: 8128:cstf1
uniprot id: I3J5B2
names: Subcellular Location Annotation
messages: Nucleus

8128:sec61a1
gene id: 8128:sec61a1
uniprot id: A0A669EGQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.
messages: Membrane
messages: Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins (By similarity). Plays a role in pronephric kidney tubule development.

8128:LOC100701647
gene id: 8128:LOC100701647
uniprot id: A0A669C5I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

8128:xpo6
gene id: 8128:xpo6
uniprot id: A0A669D4B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100706772
gene id: 8128:LOC100706772
uniprot id: A0A669F0N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

8128:igdcc3
gene id: 8128:igdcc3
uniprot id: I3JG87
names: Subcellular Location Annotation
messages: Membrane

8128:mboat1
gene id: 8128:mboat1
uniprot id: I3JJ69
names: Subcellular Location Annotation
messages: Membrane

8128:LOC109201861
gene id: 8128:LOC109201861
uniprot id: A0A669F6T1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC109202793
gene id: 8128:LOC109202793
uniprot id: A0A669E2Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:polr2g
gene id: 8128:polr2g
uniprot id: I3JCC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: Nucleus

8128:wdr18
gene id: 8128:wdr18
uniprot id: I3JA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Dynein axonemal particle
messages: nucleolus
messages: nucleoplasm

8128:zc3h12d
gene id: 8128:zc3h12d
uniprot id: A0A669DMN8
names: Similarity
messages: Belongs to the ZC3H12 family.

8128:LOC100705962
gene id: 8128:LOC100705962
uniprot id: I3JIX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8128:LOC102080641
gene id: 8128:LOC102080641
uniprot id: A0A669DN17
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:coq4
gene id: 8128:coq4
uniprot id: I3J415
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

8128:ccnc
gene id: 8128:ccnc
uniprot id: A0A669E6H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
messages: Nucleus

8128:LOC100690023
gene id: 8128:LOC100690023
uniprot id: A0A669CNI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8128:nbn
gene id: 8128:nbn
uniprot id: I3JG26
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

8128:cdkl1
gene id: 8128:cdkl1
uniprot id: I3IVH5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100692090
gene id: 8128:LOC100692090
uniprot id: A0A669DSU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

8128:numb
gene id: 8128:numb
uniprot id: A0A669B4W7
uniprot id: I3IV49
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Plays a role in the process of neurogenesis.

8128:LOC100706048
gene id: 8128:LOC100706048
uniprot id: A0A669EFT0
uniprot id: I3K9V1
names: Similarity
messages: Belongs to the IUNH family.

8128:panx2
gene id: 8128:panx2
uniprot id: I3JW76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8128:LOC100709357
gene id: 8128:LOC100709357
uniprot id: A0A669CSL3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693736
gene id: 8128:LOC100693736
uniprot id: A0A669EGK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

8128:avpr1a
gene id: 8128:avpr1a
uniprot id: A0A669DUG4
uniprot id: I3JQK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:tent5a
gene id: 8128:tent5a
uniprot id: I3ITY8
names: Similarity
messages: Belongs to the TENT family.

8128:derl1
gene id: 8128:derl1
uniprot id: I3JJZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

8128:LOC100708136
gene id: 8128:LOC100708136
uniprot id: I3JGJ2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8128:acss2
gene id: 8128:acss2
uniprot id: A0A669EMV0
uniprot id: I3KC26
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8128:serpinf1
gene id: 8128:serpinf1
uniprot id: A0A669B2H8
names: Similarity
messages: Belongs to the serpin family.

8128:egflam
gene id: 8128:egflam
uniprot id: A0A669BAG2
uniprot id: A0A669DG55
uniprot id: I3KCH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:spice1
gene id: 8128:spice1
uniprot id: I3K9D1
names: Subcellular Location Annotation
messages: centriole
messages: spindle

8128:LOC100708715
gene id: 8128:LOC100708715
uniprot id: I3KPF1
names: Similarity
messages: Belongs to the TMEM106 family.

8128:LOC100696600
gene id: 8128:LOC100696600
uniprot id: A0A669BC22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

8128:LOC100709086
gene id: 8128:LOC100709086
uniprot id: A0A669D045
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:tmem234
gene id: 8128:tmem234
uniprot id: I3J6E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

8128:LOC100702713
gene id: 8128:LOC100702713
uniprot id: A0A669F9U8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.

8128:gjc2
gene id: 8128:gjc2
uniprot id: I3JSR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:utp6
gene id: 8128:utp6
uniprot id: I3KNU6
names: Similarity
messages: Belongs to the UTP6 family.

8128:ubl3
gene id: 8128:ubl3
uniprot id: A0A669CW98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:fam219b
gene id: 8128:fam219b
uniprot id: I3J4A6
names: Similarity
messages: Belongs to the FAM219 family.

8128:map1lc3a
gene id: 8128:map1lc3a
uniprot id: A0A669E0Y3
names: Similarity
messages: Belongs to the ATG8 family.

8128:acer2
gene id: 8128:acer2
uniprot id: I3KAY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:rdh10
gene id: 8128:rdh10
uniprot id: I3KA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8128:tmem267
gene id: 8128:tmem267
uniprot id: A0A669DNG8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC109199328
gene id: 8128:LOC109199328
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:tent5b
gene id: 8128:tent5b
uniprot id: A0A669FAB6
names: Similarity
messages: Belongs to the TENT family.

8128:dhrsx
gene id: 8128:dhrsx
uniprot id: I3JK77
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:sbf1
gene id: 8128:sbf1
uniprot id: A0A669AX59
uniprot id: A0A669BUN0
uniprot id: A0A669EKZ1
uniprot id: I3K1M8
uniprot id: I3K1M9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8128:tsnare1
gene id: 8128:tsnare1
uniprot id: I3JMG0
names: Similarity
messages: Belongs to the syntaxin family.

8128:LOC100693557
gene id: 8128:LOC100693557
uniprot id: A0A669AZF7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100712564
gene id: 8128:LOC100712564
uniprot id: A0A669CGI6
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

8128:LOC100702126
gene id: 8128:LOC100702126
uniprot id: I3JYW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

8128:sec24a
gene id: 8128:sec24a
uniprot id: A0A669CM55
uniprot id: A0A669DGY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8128:rcan1
gene id: 8128:rcan1
uniprot id: A0A669B0G0
names: Similarity
messages: Belongs to the RCAN family.

8128:mical2
gene id: 8128:mical2
uniprot id: A0A669CXK3
uniprot id: A0A669D5W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

8128:cdk10
gene id: 8128:cdk10
uniprot id: I3JY21
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:st13
gene id: 8128:st13
uniprot id: I3JP42
names: Similarity
messages: Belongs to the FAM10 family.

8128:LOC100696541
gene id: 8128:LOC100696541
uniprot id: A0A669CGU3
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

8128:LOC100708037
gene id: 8128:LOC100708037
uniprot id: A0A669EHJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100702861
gene id: 8128:LOC100702861
uniprot id: A0A669BVA5
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

8128:LOC100703753
gene id: 8128:LOC100703753
uniprot id: A0A669CED2
names: Similarity
messages: Belongs to the cullin family.

8128:vps28
gene id: 8128:vps28
uniprot id: A0A669CRL8
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

8128:LOC100709916
gene id: 8128:LOC100709916
uniprot id: A0A669BWE6
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:LOC100704654
gene id: 8128:LOC100704654
uniprot id: I3JX29
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100707937
gene id: 8128:LOC100707937
uniprot id: A0A669B0M6
names: Similarity
messages: Belongs to the CNKSR family.

8128:kxd1
gene id: 8128:kxd1
uniprot id: I3KBY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Lysosome membrane

8128:gipc3
gene id: 8128:gipc3
uniprot id: A0A669BCD6
names: Similarity
messages: Belongs to the GIPC family.

8128:LOC100705600
gene id: 8128:LOC100705600
uniprot id: A0A669BSE0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:upf2
gene id: 8128:upf2
uniprot id: I3KNH3
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100694102
gene id: 8128:LOC100694102
uniprot id: I3KN40
names: Similarity
messages: Belongs to the FAM53 family.

8128:agtr1
gene id: 8128:agtr1
uniprot id: A0A669DYH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

8128:mark2
gene id: 8128:mark2
uniprot id: I3K7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

8128:anxa6
gene id: 8128:anxa6
uniprot id: I3KMK5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

8128:cyp17
gene id: 8128:cyp17
uniprot id: A7M6G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction.
messages: Membrane

8128:LOC100710178
gene id: 8128:LOC100710178
uniprot id: A0A669AXR3
uniprot id: A0A669BQH0
uniprot id: A0A669E8U9
uniprot id: A0A669ER78
uniprot id: I3KE27
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:coq6
gene id: 8128:coq6
uniprot id: I3KWA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

8128:LOC100707370
gene id: 8128:LOC100707370
uniprot id: I3K7A8
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

8128:LOC100710341
gene id: 8128:LOC100710341
uniprot id: I3J6Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

8128:trap1
gene id: 8128:trap1
uniprot id: A0A669CR91
names: Similarity
messages: Belongs to the heat shock protein 90 family.

8128:golga5
gene id: 8128:golga5
uniprot id: I3KU92
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.
messages: Membrane

8128:myod2
gene id: 8128:myod2
uniprot id: D2XRC1
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8128:LOC100709063
gene id: 8128:LOC100709063
uniprot id: I3KME5
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693550
gene id: 8128:LOC100693550
uniprot id: I3JIM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane

8128:mrpl46
gene id: 8128:mrpl46
uniprot id: A0A669FC70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

8128:gys1
gene id: 8128:gys1
uniprot id: A0A669BG48
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

8128:zfp36l1
gene id: 8128:zfp36l1
uniprot id: A0A669B6R2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8128:LOC100703239
gene id: 8128:LOC100703239
uniprot id: A0A669BZL7
names: Similarity
messages: Belongs to the asteroid family.

8128:LOC100706108
gene id: 8128:LOC100706108
uniprot id: A0A669BYH2
names: Similarity
messages: Belongs to the AFG1 ATPase family.

8128:vhl
gene id: 8128:vhl
uniprot id: A0A669DC22
names: Similarity
messages: Belongs to the VHL family.

8128:slc2a5
gene id: 8128:slc2a5
uniprot id: A0A669F0E0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8128:LOC100690969
gene id: 8128:LOC100690969
uniprot id: A0A669B553
uniprot id: A0A669C4P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8128:LOC100708135
gene id: 8128:LOC100708135
uniprot id: A0A669E5C2
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

8128:ext2
gene id: 8128:ext2
uniprot id: I3JFZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8128:ovca2
gene id: 8128:ovca2
uniprot id: I3JDV9
names: Similarity
messages: Belongs to the LovG family.

8128:usp44
gene id: 8128:usp44
uniprot id: A0A669E8G0
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:LOC100699342
gene id: 8128:LOC100699342
uniprot id: A0A669DCD8
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

8128:spx
gene id: 8128:spx
uniprot id: A0A650AWI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

8128:LOC102077535
gene id: 8128:LOC102077535
uniprot id: A0A669AW33
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:rap1gds1
gene id: 8128:rap1gds1
uniprot id: I3KV45
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: cytosol

8128:LOC100711526
gene id: 8128:LOC100711526
uniprot id: I3IWK4
names: Similarity
messages: Belongs to the peptidase S1C family.

8128:LOC100706293
gene id: 8128:LOC100706293
uniprot id: A0A669BHF3
names: Subcellular Location Annotation
messages: Cytoplasm

8128:dcn
gene id: 8128:dcn
uniprot id: Q9DE03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN.
messages: May affect the rate of fibrils formation.
messages: extracellular matrix

8128:sap130
gene id: 8128:sap130
uniprot id: I3KT60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

8128:LOC100693769
gene id: 8128:LOC100693769
uniprot id: I3JDD6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100700345
gene id: 8128:LOC100700345
uniprot id: I3J520
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

8128:sost
gene id: 8128:sost
uniprot id: A0A669DK72
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the sclerostin family.
messages: Interacts with LRP4 (via the extracellular domain); the interaction facilitates the inhibition of Wnt signaling. Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling. Interacts with LRP6.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

8128:LOC102078219
gene id: 8128:LOC102078219
uniprot id: A0A669BZH0
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

8128:LOC100710529
gene id: 8128:LOC100710529
uniprot id: A0A669CXG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

8128:LOC102079948
gene id: 8128:LOC102079948
uniprot id: A0A669CUA2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100691565
gene id: 8128:LOC100691565
uniprot id: A0A669DMD8
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8128:LOC100703068
gene id: 8128:LOC100703068
uniprot id: A0A669F6K7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

8128:LOC100706616
gene id: 8128:LOC100706616
uniprot id: A0A669AZ89
names: Similarity
messages: Belongs to the BolA/IbaG family.

8128:LOC100694634
gene id: 8128:LOC100694634
uniprot id: I3KWJ1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8128:tsr2
gene id: 8128:tsr2
uniprot id: I3IWH4
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

8128:me3
gene id: 8128:me3
uniprot id: A0A669EDY5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

8128:gpn2
gene id: 8128:gpn2
uniprot id: A0A669CID4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

8128:LOC100690829
gene id: 8128:LOC100690829
uniprot id: I3KML9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8128:rmi1
gene id: 8128:rmi1
uniprot id: A0A669CIW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RMI1 family.
messages: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
messages: Nucleus

8128:utp23
gene id: 8128:utp23
uniprot id: A0A669F6T4
names: Subcellular Location Annotation
messages: nucleolus

8128:LOC109204179
gene id: 8128:LOC109204179
uniprot id: A0A669DL86
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC102080227
gene id: 8128:LOC102080227
uniprot id: A0A669B1J1
uniprot id: A0A669BRK7
names: Similarity
messages: Belongs to the CCSER family.

8128:LOC100710659
gene id: 8128:LOC100710659
uniprot id: A0A669DDE5
names: Similarity
messages: Belongs to the cystatin family.

8128:hoxc12
gene id: 8128:hoxc12
uniprot id: A0A669EFT7
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100703227
gene id: 8128:LOC100703227
uniprot id: A0A669C663
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100708222
gene id: 8128:LOC100708222
uniprot id: I3JZD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100700110
gene id: 8128:LOC100700110
uniprot id: A0A669CSR8
names: Similarity
messages: Belongs to the TAFA family.

8128:lrig2
gene id: 8128:lrig2
uniprot id: A0A669D042
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693756
gene id: 8128:LOC100693756
uniprot id: A0A669BMI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8128:top3a
gene id: 8128:top3a
uniprot id: I3JP29
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

8128:LOC100695816
gene id: 8128:LOC100695816
uniprot id: A0A669EIK7
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:upf1
gene id: 8128:upf1
uniprot id: I3K4H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

8128:nrn1l
gene id: 8128:nrn1l
uniprot id: A0A669C275
names: Similarity
messages: Belongs to the neuritin family.

8128:LOC100711647
gene id: 8128:LOC100711647
uniprot id: A0A669E5D9
uniprot id: I3J876
names: Similarity
messages: Belongs to the ARTD/PARP family.

8128:LOC100709512
gene id: 8128:LOC100709512
uniprot id: I3JFZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8128:nsg1
gene id: 8128:nsg1
uniprot id: I3KTK9
names: Similarity
messages: Belongs to the NSG family.

8128:LOC100696228
gene id: 8128:LOC100696228
uniprot id: A0A669E2G8
names: Caution
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100710709
gene id: 8128:LOC100710709
uniprot id: I3KJR3
names: Similarity
messages: Belongs to the FAM83 family.

8128:ednra
gene id: 8128:ednra
uniprot id: I3JUP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

8128:LOC100707639
gene id: 8128:LOC100707639
uniprot id: I3J1X2
names: Similarity
messages: Belongs to the MS4A family.

8128:naa40
gene id: 8128:naa40
uniprot id: A0A669CS03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

8128:eif4a2
gene id: 8128:eif4a2
uniprot id: A0A669E086
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

8128:LOC100701740
gene id: 8128:LOC100701740
uniprot id: I3J8F9
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC109194559
gene id: 8128:LOC109194559
uniprot id: A0A669ETE4
names: Function
names: Similarity
names: Subunit
messages: Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.
messages: Belongs to the fucolectin family.
messages: Homotrimer.

8128:vwa2
gene id: 8128:vwa2
uniprot id: I3KHP4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:dad1
gene id: 8128:dad1
uniprot id: I3JRC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8128:psme2
gene id: 8128:psme2
uniprot id: I3JHK6
names: Similarity
messages: Belongs to the PA28 family.

8128:LOC109200154
gene id: 8128:LOC109200154
uniprot id: A0A669D3Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100707247
gene id: 8128:LOC100707247
uniprot id: I3KJV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

8128:exosc3
gene id: 8128:exosc3
uniprot id: A0A669E3W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm

8128:dclre1a
gene id: 8128:dclre1a
uniprot id: I3KHL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

8128:lg12h9orf78
gene id: 8128:lg12h9orf78
uniprot id: A0A669BF36
names: Similarity
messages: Belongs to the TLS1 family.

8128:LOC100696119
gene id: 8128:LOC100696119
uniprot id: I3KXT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

8128:steap2
gene id: 8128:steap2
uniprot id: I3JTD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

8128:LOC100712278
gene id: 8128:LOC100712278
uniprot id: A0A669DJX7
uniprot id: I3J2S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:mtx3
gene id: 8128:mtx3
uniprot id: I3K842
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

8128:habp2
gene id: 8128:habp2
uniprot id: A0A669DNA3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:mrpl52
gene id: 8128:mrpl52
uniprot id: I3KNC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

8128:LOC100706428
gene id: 8128:LOC100706428
uniprot id: A0A669BKV9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:eed
gene id: 8128:eed
uniprot id: I3JJF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ESC family.
messages: Nucleus

8128:lig4
gene id: 8128:lig4
uniprot id: I3K1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

8128:LOC100707774
gene id: 8128:LOC100707774
uniprot id: I3KV16
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8128:hoxa11
gene id: 8128:hoxa11
uniprot id: I3JAA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8128:ptpn6
gene id: 8128:ptpn6
uniprot id: A0A669F5J6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.

8128:LOC100694932
gene id: 8128:LOC100694932
uniprot id: I3KGK3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

8128:LOC109194736
gene id: 8128:LOC109194736
uniprot id: I3KY19
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC102082036
gene id: 8128:LOC102082036
uniprot id: A0A075QT74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

8128:LOC100698659
gene id: 8128:LOC100698659
uniprot id: A0A669B066
uniprot id: A0A669CTN7
uniprot id: A0A669F2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

8128:vta1
gene id: 8128:vta1
uniprot id: A0A669D7N7
uniprot id: A0A669EX18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

8128:amotl2
gene id: 8128:amotl2
uniprot id: I3KT59
names: Similarity
messages: Belongs to the angiomotin family.

8128:LOC100709221
gene id: 8128:LOC100709221
uniprot id: A0A669BC75
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

8128:LOC100712456
gene id: 8128:LOC100712456
uniprot id: A0A669BTE8
uniprot id: I3J8B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate.
messages: Membrane

8128:LOC100695765
gene id: 8128:LOC100695765
uniprot id: I3JQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

8128:calhm1
gene id: 8128:calhm1
uniprot id: A0A669CJ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

8128:prepl
gene id: 8128:prepl
uniprot id: I3IX40
names: Similarity
messages: Belongs to the peptidase S9A family.

8128:LOC106098416
gene id: 8128:LOC106098416
uniprot id: A0A669E908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

8128:LOC100706613
gene id: 8128:LOC100706613
uniprot id: I3IXV9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100697245
gene id: 8128:LOC100697245
uniprot id: A0A669DGF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

8128:LOC100710609
gene id: 8128:LOC100710609
uniprot id: I3JIX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8128:gata2
gene id: 8128:gata2
uniprot id: I3KS72
names: Subcellular Location Annotation
messages: Nucleus

8128:usp39
gene id: 8128:usp39
uniprot id: I3K6L7
names: Subcellular Location Annotation
messages: Nucleus

8128:polr3c
gene id: 8128:polr3c
uniprot id: I3JGN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

8128:LOC100696337
gene id: 8128:LOC100696337
uniprot id: A0A669E085
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8128:LOC109204964
gene id: 8128:LOC109204964
uniprot id: A0A669BSA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:pdss1
gene id: 8128:pdss1
uniprot id: I3JGT4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8128:oaf
gene id: 8128:oaf
uniprot id: A0A669C377
names: Similarity
messages: Belongs to the OAF family.

8128:mfsd11
gene id: 8128:mfsd11
uniprot id: I3JSJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

8128:LOC102081239
gene id: 8128:LOC102081239
uniprot id: A0A669EIL6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

8128:chst2
gene id: 8128:chst2
uniprot id: I3KXB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8128:LOC109198557
gene id: 8128:LOC109198557
uniprot id: A0A669C6I7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8128:unc50
gene id: 8128:unc50
uniprot id: I3KDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

8128:LOC100706113
gene id: 8128:LOC100706113
uniprot id: I3J6X7
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

8128:LOC100700065
gene id: 8128:LOC100700065
uniprot id: I3KJU3
names: Similarity
messages: Belongs to the PPP4R2 family.

8128:pde4c
gene id: 8128:pde4c
uniprot id: A0A669BJL1
uniprot id: A0A669D4S9
uniprot id: A0A669E1X7
uniprot id: I3K4F3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC106097808
gene id: 8128:LOC106097808
uniprot id: A0A669E2C7
names: Subcellular Location Annotation
messages: Nucleus

8128:brf1
gene id: 8128:brf1
uniprot id: I3IUM5
names: Similarity
messages: Belongs to the TFIIB family.
messages: Belongs to the cyclin family. Cyclin AB subfamily.

8128:nelfe
gene id: 8128:nelfe
uniprot id: I3K797
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus

8128:LOC100707194
gene id: 8128:LOC100707194
uniprot id: A0A669BMF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100705177
gene id: 8128:LOC100705177
uniprot id: I3K3Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8128:pi4k2b
gene id: 8128:pi4k2b
uniprot id: I3J6C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

8128:alg13
gene id: 8128:alg13
uniprot id: I3JD92
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

8128:LOC100703561
gene id: 8128:LOC100703561
uniprot id: A0A669C066
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

8128:gpt
gene id: 8128:gpt
uniprot id: I3KAH6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

8128:LOC100706999
gene id: 8128:LOC100706999
uniprot id: A0A669B9L6
uniprot id: I3IZI4
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8128:LOC102082805
gene id: 8128:LOC102082805
uniprot id: I3KN46
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:dtx1
gene id: 8128:dtx1
uniprot id: I3JXS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8128:LOC109202491
gene id: 8128:LOC109202491
uniprot id: A0A669EZ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

8128:LOC100699900
gene id: 8128:LOC100699900
uniprot id: I3KC82
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8128:duox1
gene id: 8128:duox1
uniprot id: I3JNR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

8128:dtx3
gene id: 8128:dtx3
uniprot id: A0A669CYU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8128:hsd17b1
gene id: 8128:hsd17b1
uniprot id: Q49RB1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:slc7a10
gene id: 8128:slc7a10
uniprot id: A0A669DU94
names: Subcellular Location Annotation
messages: Membrane

8128:tctn1
gene id: 8128:tctn1
uniprot id: I3K0G0
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

8128:vps33b
gene id: 8128:vps33b
uniprot id: I3JIU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8128:mettl15
gene id: 8128:mettl15
uniprot id: I3J4E1
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

8128:mrpl32
gene id: 8128:mrpl32
uniprot id: A0A669AVT1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

8128:LOC100698935
gene id: 8128:LOC100698935
uniprot id: A0A669B2Q6
names: Similarity
names: Subunit
messages: Belongs to the uridine kinase family.
messages: Homotetramer.

8128:sgce
gene id: 8128:sgce
uniprot id: A0A669AVY6
uniprot id: A0A669BV68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Golgi apparatus
messages: dendrite
messages: sarcolemma

8128:ints12
gene id: 8128:ints12
uniprot id: I3KLV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 12 family.
messages: Nucleus

8128:wisp1
gene id: 8128:wisp1
uniprot id: I3J188
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:mrap2
gene id: 8128:mrap2
uniprot id: A0A669DIP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC109194293
gene id: 8128:LOC109194293
uniprot id: I3KPF0
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8128:LOC100693896
gene id: 8128:LOC100693896
uniprot id: I3J1M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:sgsh
gene id: 8128:sgsh
uniprot id: I3KMN2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8128:pick1
gene id: 8128:pick1
uniprot id: A0A669DEM6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
messages: cytoskeleton
messages: perinuclear region
messages: synaptosome

8128:gcnt7
gene id: 8128:gcnt7
uniprot id: I3JIB9
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100691157
gene id: 8128:LOC100691157
uniprot id: A0A669BH94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

8128:adcy7
gene id: 8128:adcy7
uniprot id: A0A669BGH4
uniprot id: I3J3Y4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8128:aga
gene id: 8128:aga
uniprot id: I3IXZ2
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8128:psma8
gene id: 8128:psma8
uniprot id: A0A669BSJ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8128:lmod2
gene id: 8128:lmod2
uniprot id: I3K132
names: Subcellular Location Annotation
messages: cytoskeleton

8128:capn9
gene id: 8128:capn9
uniprot id: A0A669C4Q8
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:vkorc1l1
gene id: 8128:vkorc1l1
uniprot id: I3K4N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100707208
gene id: 8128:LOC100707208
uniprot id: I3JL09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

8128:pdgfra
gene id: 8128:pdgfra
uniprot id: A0A669DY06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100694923
gene id: 8128:LOC100694923
uniprot id: I3JHC5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:mvd
gene id: 8128:mvd
uniprot id: A0A669CV21
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

8128:ino80c
gene id: 8128:ino80c
uniprot id: I3JFD1
names: Subcellular Location Annotation
messages: Nucleus

8128:gdf5
gene id: 8128:gdf5
uniprot id: A0A669EY86
names: Similarity
messages: Belongs to the TGF-beta family.

8128:nr2c1
gene id: 8128:nr2c1
uniprot id: I3JPH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:pa2g4
gene id: 8128:pa2g4
uniprot id: A0A669F2T2
names: Similarity
messages: Belongs to the peptidase M24 family.

8128:LOC100696948
gene id: 8128:LOC100696948
uniprot id: A0A669B6M4
uniprot id: A0A669EFK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

8128:eral1
gene id: 8128:eral1
uniprot id: A0A669ES61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.

8128:LOC109204054
gene id: 8128:LOC109204054
uniprot id: A0A669C0Z8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100711455
gene id: 8128:LOC100711455
uniprot id: I3KSS9
names: Similarity
messages: Belongs to the PMEL/NMB family.

8128:bop1
gene id: 8128:bop1
uniprot id: A0A669ERK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

8128:LOC100696446
gene id: 8128:LOC100696446
uniprot id: I3JUX9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

8128:epha3
gene id: 8128:epha3
uniprot id: A0A669CXE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:satb1
gene id: 8128:satb1
uniprot id: A0A669DC33
uniprot id: A0A669EZZ8
names: Similarity
messages: Belongs to the CUT homeobox family.

8128:LOC100707365
gene id: 8128:LOC100707365
uniprot id: A0A669EKM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

8128:mixl1
gene id: 8128:mixl1
uniprot id: I3K757
names: Subcellular Location Annotation
messages: Nucleus

8128:pcsk7
gene id: 8128:pcsk7
uniprot id: A0A669EB91
names: Similarity
messages: Belongs to the peptidase S8 family.

8128:LOC102079944
gene id: 8128:LOC102079944
uniprot id: A0A669B388
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

8128:gcgr
gene id: 8128:gcgr
uniprot id: I3J0U5
names: Subcellular Location Annotation
messages: Membrane

8128:ret
gene id: 8128:ret
uniprot id: A0A669DRH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.

8128:LOC100696784
gene id: 8128:LOC100696784
uniprot id: I3JBR0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:ebag9
gene id: 8128:ebag9
uniprot id: I3ITX8
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

8128:stard3nl
gene id: 8128:stard3nl
uniprot id: I3KMJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8128:LOC100690639
gene id: 8128:LOC100690639
uniprot id: I3JNH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

8128:abcd3
gene id: 8128:abcd3
uniprot id: I3JTF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

8128:veph1
gene id: 8128:veph1
uniprot id: A0A669BNL0
uniprot id: I3JDM8
names: Similarity
messages: Belongs to the MELT/VEPH family.

8128:rfx1
gene id: 8128:rfx1
uniprot id: A0A669B865
names: Subcellular Location Annotation
messages: Nucleus

8128:sar1a
gene id: 8128:sar1a
uniprot id: A0A669B6U9
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

8128:LOC100706731
gene id: 8128:LOC100706731
uniprot id: A0A669ERF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8128:LOC100711015
gene id: 8128:LOC100711015
uniprot id: I3KZY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:fgf6
gene id: 8128:fgf6
uniprot id: A0A669C7A9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:LOC100699527
gene id: 8128:LOC100699527
uniprot id: A0A669DCT5
uniprot id: A0A669EGE6
names: Similarity
messages: Belongs to the canopy family.

8128:ap5m1
gene id: 8128:ap5m1
uniprot id: I3KWA2
names: Subcellular Location Annotation
names: Subunit
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

8128:cnih4
gene id: 8128:cnih4
uniprot id: A0A669F9U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

8128:adgra1
gene id: 8128:adgra1
uniprot id: A0A669CFF2
names: Subcellular Location Annotation
messages: Membrane

8128:tcp11
gene id: 8128:tcp11
uniprot id: I3KBT8
names: Similarity
messages: Belongs to the TCP11 family.

8128:sdha
gene id: 8128:sdha
uniprot id: I3JJX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

8128:LOC100706587
gene id: 8128:LOC100706587
uniprot id: I3JHL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100708522
gene id: 8128:LOC100708522
uniprot id: I3K888
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100696880
gene id: 8128:LOC100696880
uniprot id: I3JCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:chst10
gene id: 8128:chst10
uniprot id: I3K2T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100702227
gene id: 8128:LOC100702227
uniprot id: A0A669F381
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:sys1
gene id: 8128:sys1
uniprot id: A0A669BCS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

8128:LOC100705767
gene id: 8128:LOC100705767
uniprot id: A0A669BGD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC100708288
gene id: 8128:LOC100708288
uniprot id: I3KGB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8128:LOC102080862
gene id: 8128:LOC102080862
uniprot id: A0A669F5D1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100701393
gene id: 8128:LOC100701393
uniprot id: A0A669C370
uniprot id: A0A669CE14
uniprot id: A0A669DF13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

8128:top2a
gene id: 8128:top2a
uniprot id: I3KVE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

8128:LOC100712138
gene id: 8128:LOC100712138
uniprot id: I3K4F0
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100709091
gene id: 8128:LOC100709091
uniprot id: A0A669DAF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8128:bola3
gene id: 8128:bola3
uniprot id: A0A669CHD5
names: Similarity
messages: Belongs to the BolA/IbaG family.

8128:LOC109194519
gene id: 8128:LOC109194519
uniprot id: A0A669C5L9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:fermt1
gene id: 8128:fermt1
uniprot id: A0A669BCL7
uniprot id: A0A669DR73
uniprot id: A0A669DU01
names: Similarity
messages: Belongs to the kindlin family.

8128:ndufa6
gene id: 8128:ndufa6
uniprot id: A0A669EMT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8128:ugt8
gene id: 8128:ugt8
uniprot id: A0A669E1K9
uniprot id: I3KB76
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

8128:ing1
gene id: 8128:ing1
uniprot id: I3KA62
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8128:tbx5
gene id: 8128:tbx5
uniprot id: A0A669BXN2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:LOC100704579
gene id: 8128:LOC100704579
uniprot id: I3KUV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:LOC100706789
gene id: 8128:LOC100706789
uniprot id: A0A669DCU3
names: Similarity
messages: Belongs to the FAM20 family.

8128:LOC100703777
gene id: 8128:LOC100703777
uniprot id: A0A669BN08
uniprot id: A0A669CN70
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100710254
gene id: 8128:LOC100710254
uniprot id: A0A669EGL0
uniprot id: I3KHH5
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

8128:acox1
gene id: 8128:acox1
uniprot id: W6E7X1
uniprot id: W6EJV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

8128:LOC100703709
gene id: 8128:LOC100703709
uniprot id: A0A669DP12
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8128:LOC100695758
gene id: 8128:LOC100695758
uniprot id: A0A669ETZ1
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:LOC100711896
gene id: 8128:LOC100711896
uniprot id: I3J894
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100694572
gene id: 8128:LOC100694572
uniprot id: A0A669E489
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

8128:grin2b
gene id: 8128:grin2b
uniprot id: A0A669C4W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

8128:LOC100689719
gene id: 8128:LOC100689719
uniprot id: A0A669CVK5
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

8128:gdap1
gene id: 8128:gdap1
uniprot id: I3KA48
names: Similarity
messages: Belongs to the GST superfamily.

8128:mat2a
gene id: 8128:mat2a
uniprot id: I3K6L3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

8128:LOC102080408
gene id: 8128:LOC102080408
uniprot id: A0A669DB11
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:tbx20
gene id: 8128:tbx20
uniprot id: I3JHH5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:aasdhppt
gene id: 8128:aasdhppt
uniprot id: I3JBZ5
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

8128:tbx15
gene id: 8128:tbx15
uniprot id: I3KF48
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:LOC100706327
gene id: 8128:LOC100706327
uniprot id: A0A669C9P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8128:atp2b2
gene id: 8128:atp2b2
uniprot id: A0A669B5J7
uniprot id: A0A669F776
uniprot id: I3KAA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:chst12
gene id: 8128:chst12
uniprot id: I3J5H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:adamts1
gene id: 8128:adamts1
uniprot id: I3K2F8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:puf60
gene id: 8128:puf60
uniprot id: I3JG79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

8128:fam160a1
gene id: 8128:fam160a1
uniprot id: I3JUU8
names: Similarity
messages: Belongs to the FHIP family.

8128:LOC100711031
gene id: 8128:LOC100711031
uniprot id: A0A669EF67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

8128:meaf6
gene id: 8128:meaf6
uniprot id: I3K7U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

8128:hsd3b7
gene id: 8128:hsd3b7
uniprot id: B9UN14
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8128:LOC100711257
gene id: 8128:LOC100711257
uniprot id: A0A669BXX5
uniprot id: A0A669E8E6
uniprot id: I3KTZ5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100700825
gene id: 8128:LOC100700825
uniprot id: I3JHB7
names: Subcellular Location Annotation
messages: cytoskeleton

8128:alg8
gene id: 8128:alg8
uniprot id: I3JKF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:nr4a2
gene id: 8128:nr4a2
uniprot id: A0A669E453
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100710519
gene id: 8128:LOC100710519
uniprot id: I3K9Y3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC109201905
gene id: 8128:LOC109201905
uniprot id: A0A669DXY9
names: Similarity
messages: Belongs to the globin family.

8128:LOC100690069
gene id: 8128:LOC100690069
uniprot id: A0A669ESK5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:esco2
gene id: 8128:esco2
uniprot id: I3J867
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100702909
gene id: 8128:LOC100702909
uniprot id: A0A669D7Y4
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8128:bet1
gene id: 8128:bet1
uniprot id: A0A669C7X1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100692823
gene id: 8128:LOC100692823
uniprot id: A0A0E3JI84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Membrane raft

8128:LOC100707395
gene id: 8128:LOC100707395
uniprot id: I3JHQ1
names: Similarity
messages: Belongs to the SOGA family.

8128:gpr183
gene id: 8128:gpr183
uniprot id: I3KXE4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:ndc1
gene id: 8128:ndc1
uniprot id: I3KQF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

8128:castor1
gene id: 8128:castor1
uniprot id: A0A669E8A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GATS family.
messages: cytosol

8128:LOC100689863
gene id: 8128:LOC100689863
uniprot id: I3J1F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

8128:LOC100692805
gene id: 8128:LOC100692805
uniprot id: A0A669E0C2
uniprot id: I3K536
names: Similarity
messages: Belongs to the thioredoxin family.

8128:LOC100704282
gene id: 8128:LOC100704282
uniprot id: I3JWY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8128:LOC100690049
gene id: 8128:LOC100690049
uniprot id: A0A669DHL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:nptx1
gene id: 8128:nptx1
uniprot id: A0A669CFB1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100703437
gene id: 8128:LOC100703437
uniprot id: I3JGX1
names: Subcellular Location Annotation
messages: Nucleus

8128:epha4
gene id: 8128:epha4
uniprot id: I3KBB3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8128:rorb
gene id: 8128:rorb
uniprot id: I3JXD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:pus1
gene id: 8128:pus1
uniprot id: I3J7E3
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

8128:LOC100691660
gene id: 8128:LOC100691660
uniprot id: I3KL40
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:drc1
gene id: 8128:drc1
uniprot id: A0A669DW09
uniprot id: I3K6F3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DRC1 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: cilium axoneme
messages: flagellum axoneme

8128:tmem9b
gene id: 8128:tmem9b
uniprot id: A0A669CEZ7
names: Similarity
messages: Belongs to the TMEM9 family.

8128:thbs3
gene id: 8128:thbs3
uniprot id: A0A669B7Y3
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100534440
gene id: 8128:LOC100534440
uniprot id: B7SU43
uniprot id: I3KY33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8128:LOC100700067
gene id: 8128:LOC100700067
uniprot id: A0A669AVX0
names: Subcellular Location Annotation
messages: Membrane

8128:mapre1
gene id: 8128:mapre1
uniprot id: I3KC33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: centrosome
messages: spindle pole

8128:sh3rf3
gene id: 8128:sh3rf3
uniprot id: I3J917
names: Similarity
messages: Belongs to the SH3RF family.

8128:LOC100711830
gene id: 8128:LOC100711830
uniprot id: I3J7N1
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8128:ganab
gene id: 8128:ganab
uniprot id: A0A669C319
uniprot id: I3JCS3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

8128:LOC100697722
gene id: 8128:LOC100697722
uniprot id: A0A669BLR1
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8128:LOC100696646
gene id: 8128:LOC100696646
uniprot id: I3K6Q3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100708400
gene id: 8128:LOC100708400
uniprot id: A0A669EHY0
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

8128:LOC100702967
gene id: 8128:LOC100702967
uniprot id: I3KAU6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

8128:polr2f
gene id: 8128:polr2f
uniprot id: A0A669DUC5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: Nucleus

8128:LOC100704461
gene id: 8128:LOC100704461
uniprot id: I3KDI9
names: Similarity
messages: Belongs to the IUNH family.

8128:LOC100699409
gene id: 8128:LOC100699409
uniprot id: I3KL27
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

8128:LOC100695752
gene id: 8128:LOC100695752
uniprot id: A0A669ENL8
names: Similarity
messages: Belongs to the TGF-beta family.

8128:LOC100706315
gene id: 8128:LOC100706315
uniprot id: A0A669D5B5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8128:LOC100702855
gene id: 8128:LOC100702855
uniprot id: A0A669BAV0
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100689976
gene id: 8128:LOC100689976
uniprot id: A0A669FBN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Secreted

8128:LOC100692776
gene id: 8128:LOC100692776
uniprot id: A0A669EH94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8128:LOC100703172
gene id: 8128:LOC100703172
uniprot id: A0A669BF19
uniprot id: A0A669BGC6
uniprot id: A0A669DT67
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8128:LOC100701380
gene id: 8128:LOC100701380
uniprot id: I3KFP0
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8128:gck
gene id: 8128:gck
uniprot id: A0A669B6D3
names: Similarity
messages: Belongs to the hexokinase family.

8128:psmc4
gene id: 8128:psmc4
uniprot id: A0A669AW13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
messages: Cytoplasm

8128:LOC100708185
gene id: 8128:LOC100708185
uniprot id: I3J0V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

8128:LOC100696557
gene id: 8128:LOC100696557
uniprot id: A0A669DTI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

8128:LOC102078816
gene id: 8128:LOC102078816
uniprot id: I3JIM9
names: Subcellular Location Annotation
messages: Membrane

8128:hnmt
gene id: 8128:hnmt
uniprot id: A0A669EYY6
names: Subunit
messages: Monomer.

8128:LOC100707235
gene id: 8128:LOC100707235
uniprot id: I3KXQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8128:ptpn11
gene id: 8128:ptpn11
uniprot id: I3KDR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

8128:gamt
gene id: 8128:gamt
uniprot id: A0A669BYD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor.
messages: Monomer.

8128:eef2
gene id: 8128:eef2
uniprot id: I3JVG0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

8128:prim2
gene id: 8128:prim2
uniprot id: I3JTQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

8128:LOC100698682
gene id: 8128:LOC100698682
uniprot id: I3JCM1
names: Subcellular Location Annotation
messages: Nucleus

8128:hprt1
gene id: 8128:hprt1
uniprot id: A0A669C6A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

8128:crebl2
gene id: 8128:crebl2
uniprot id: I3JKX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

8128:kcnk13
gene id: 8128:kcnk13
uniprot id: I3IXX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:gbe1
gene id: 8128:gbe1
uniprot id: A0A669BP30
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

8128:arl14
gene id: 8128:arl14
uniprot id: A0A669EY17
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8128:slc25a21
gene id: 8128:slc25a21
uniprot id: I3IXA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:slc25a43
gene id: 8128:slc25a43
uniprot id: A0A669EG19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:ppp2r2d
gene id: 8128:ppp2r2d
uniprot id: A0A669DYQ0
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

8128:LOC100701291
gene id: 8128:LOC100701291
uniprot id: I3IXP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

8128:LOC100710581
gene id: 8128:LOC100710581
uniprot id: A0A669F8U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8128:hepacam2
gene id: 8128:hepacam2
uniprot id: I3JXM9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100706370
gene id: 8128:LOC100706370
uniprot id: A0A669CS94
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100699683
gene id: 8128:LOC100699683
uniprot id: A0A669CCS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

8128:slc1a7
gene id: 8128:slc1a7
uniprot id: I3KSU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8128:ubiad1
gene id: 8128:ubiad1
uniprot id: A0A669ERJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

8128:LOC100711981
gene id: 8128:LOC100711981
uniprot id: I3KVA5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100708563
gene id: 8128:LOC100708563
uniprot id: A0A669EG52
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

8128:kars
gene id: 8128:kars
uniprot id: A0A669BFG6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

8128:aqp9
gene id: 8128:aqp9
uniprot id: I3JEP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:tekt3
gene id: 8128:tekt3
uniprot id: I3JMF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8128:scn1b
gene id: 8128:scn1b
uniprot id: A0A669BV05
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100708243
gene id: 8128:LOC100708243
uniprot id: I3KFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

8128:tmem19
gene id: 8128:tmem19
uniprot id: I3KNG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

8128:LOC100709153
gene id: 8128:LOC100709153
uniprot id: A0A669D1E0
names: Subcellular Location Annotation
messages: Membrane

8128:aff3
gene id: 8128:aff3
uniprot id: I3K9J5
names: Similarity
messages: Belongs to the AF4 family.

8128:LOC100691066
gene id: 8128:LOC100691066
uniprot id: A0A669D7T7
uniprot id: A0A669FC26
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8128:LOC100534578
gene id: 8128:LOC100534578
uniprot id: Q5VJN5
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8128:amdhd1
gene id: 8128:amdhd1
uniprot id: A0A669AVQ3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

8128:LOC100693402
gene id: 8128:LOC100693402
uniprot id: A0A669B612
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

8128:LOC100708217
gene id: 8128:LOC100708217
uniprot id: P70091
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
messages: Membrane

8128:LOC109203020
gene id: 8128:LOC109203020
uniprot id: A0A669F1W3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:kir7.1
gene id: 8128:kir7.1
uniprot id: A7BI89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:ddx47
gene id: 8128:ddx47
uniprot id: A0A669CGF6
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

8128:LOC100692548
gene id: 8128:LOC100692548
uniprot id: I3K5K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

8128:LOC100692880
gene id: 8128:LOC100692880
uniprot id: I3KAW7
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

8128:hlx
gene id: 8128:hlx
uniprot id: I3JF89
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100703825
gene id: 8128:LOC100703825
uniprot id: A0A669BTU8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100697557
gene id: 8128:LOC100697557
uniprot id: A0A669C7J0
uniprot id: I3J9D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:pxmp4
gene id: 8128:pxmp4
uniprot id: A0A669ERQ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Interacts with PEX19.
messages: Peroxisome membrane

8128:hspa14
gene id: 8128:hspa14
uniprot id: I3K9M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: cytosol

8128:LOC100691312
gene id: 8128:LOC100691312
uniprot id: I3J5C4
names: Subcellular Location Annotation
messages: Secreted

8128:LOC100693698
gene id: 8128:LOC100693698
uniprot id: A0A669DUB6
uniprot id: A0A669EP81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cytoplasm

8128:fam129a
gene id: 8128:fam129a
uniprot id: I3JLW7
names: Similarity
messages: Belongs to the Niban family.

8128:snupn
gene id: 8128:snupn
uniprot id: I3K4Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

8128:pou4f3
gene id: 8128:pou4f3
uniprot id: A0A669ESP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8128:LOC100707244
gene id: 8128:LOC100707244
uniprot id: A0A669CXW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:LOC100710342
gene id: 8128:LOC100710342
uniprot id: A0A669BWQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P33MONOX family.
messages: Cytoplasm

8128:LOC100700685
gene id: 8128:LOC100700685
uniprot id: A0A669AZX5
uniprot id: I3JGM0
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8128:malrd1
gene id: 8128:malrd1
uniprot id: A0A669EL41
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100694059
gene id: 8128:LOC100694059
uniprot id: A0A669DNE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

8128:scrn2
gene id: 8128:scrn2
uniprot id: I3J5E6
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

8128:LOC109202892
gene id: 8128:LOC109202892
uniprot id: A0A669ET21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8128:LOC100706535
gene id: 8128:LOC100706535
uniprot id: I3JRZ1
names: Similarity
messages: Belongs to the IL-6 superfamily.

8128:LOC100699485
gene id: 8128:LOC100699485
uniprot id: A0A669B496
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:gata3
gene id: 8128:gata3
uniprot id: I3KN97
names: Subcellular Location Annotation
messages: Nucleus

8128:trmt10c
gene id: 8128:trmt10c
uniprot id: I3J4Y0
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

8128:prkaa1
gene id: 8128:prkaa1
uniprot id: A0A0M4G4N9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

8128:usp15
gene id: 8128:usp15
uniprot id: A0A669BAZ4
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:LOC100691229
gene id: 8128:LOC100691229
uniprot id: A0A669C0N4
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

8128:LOC100706816
gene id: 8128:LOC100706816
uniprot id: I3KU53
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

8128:LOC100695514
gene id: 8128:LOC100695514
uniprot id: I3K839
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:hpse2
gene id: 8128:hpse2
uniprot id: I3KPP8
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

8128:celf1
gene id: 8128:celf1
uniprot id: I3JNJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

8128:ttc26
gene id: 8128:ttc26
uniprot id: I3KPB5
names: Similarity
messages: Belongs to the IFT56 family.

8128:LOC100708799
gene id: 8128:LOC100708799
uniprot id: I3JC32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC102079858
gene id: 8128:LOC102079858
uniprot id: I3JIN1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:kcnj6
gene id: 8128:kcnj6
uniprot id: I3KL73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
messages: Membrane

8128:LOC100701596
gene id: 8128:LOC100701596
uniprot id: I3KCX3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:lg18h5orf22
gene id: 8128:lg18h5orf22
uniprot id: I3KQE7
names: Similarity
messages: Belongs to the UPF0489 family.

8128:LOC100696675
gene id: 8128:LOC100696675
uniprot id: I3JUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8128:pknox1
gene id: 8128:pknox1
uniprot id: I3KLH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8128:casp7
gene id: 8128:casp7
uniprot id: A0A669EKX7
names: Similarity
messages: Belongs to the peptidase C14A family.

8128:nol12
gene id: 8128:nol12
uniprot id: I3JNT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

8128:LOC100695744
gene id: 8128:LOC100695744
uniprot id: I3KYL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:ung
gene id: 8128:ung
uniprot id: I3K703
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

8128:prdm14
gene id: 8128:prdm14
uniprot id: I3K9W9
names: Subcellular Location Annotation
messages: Nucleus

8128:ddx51
gene id: 8128:ddx51
uniprot id: I3IZK1
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:znrd1
gene id: 8128:znrd1
uniprot id: A0A669CLK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
messages: nucleolus

8128:gata5
gene id: 8128:gata5
uniprot id: I3IVE3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100694732
gene id: 8128:LOC100694732
uniprot id: A0A669F009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8128:csf1r
gene id: 8128:csf1r
uniprot id: I3K5N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100701394
gene id: 8128:LOC100701394
uniprot id: A0A669EKT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8128:vwc2
gene id: 8128:vwc2
uniprot id: I3JVZ7
names: Subcellular Location Annotation
messages: Synapse

8128:LOC100705731
gene id: 8128:LOC100705731
uniprot id: A0A669B395
uniprot id: I3JM62
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

8128:LOC100706831
gene id: 8128:LOC100706831
uniprot id: A0A669D258
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

8128:LOC100697270
gene id: 8128:LOC100697270
uniprot id: I3KHE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:lamc2
gene id: 8128:lamc2
uniprot id: I3IUS3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

8128:tmem43
gene id: 8128:tmem43
uniprot id: A0A669E366
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

8128:cmbl
gene id: 8128:cmbl
uniprot id: I3KAA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

8128:alg9
gene id: 8128:alg9
uniprot id: A0A669D1W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100695300
gene id: 8128:LOC100695300
uniprot id: I3KYS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100704388
gene id: 8128:LOC100704388
uniprot id: A0A669CVI7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8128:LOC100710487
gene id: 8128:LOC100710487
uniprot id: A0A669AYM9
uniprot id: I3JQI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC100706915
gene id: 8128:LOC100706915
uniprot id: I3J720
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8128:pomgnt1
gene id: 8128:pomgnt1
uniprot id: I3JM09
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

8128:LOC100693384
gene id: 8128:LOC100693384
uniprot id: I3JI84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum axoneme

8128:LOC100710826
gene id: 8128:LOC100710826
uniprot id: I3J278
names: Subcellular Location Annotation
messages: extracellular space

8128:gmpr
gene id: 8128:gmpr
uniprot id: A0A669CQY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

8128:slu7
gene id: 8128:slu7
uniprot id: I3K5A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

8128:LOC100698187
gene id: 8128:LOC100698187
uniprot id: A0A669CVV0
uniprot id: A0A669DC81
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100711948
gene id: 8128:LOC100711948
uniprot id: A0A669DKI6
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

8128:wfikkn1
gene id: 8128:wfikkn1
uniprot id: I3KRI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Membrane

8128:timm13
gene id: 8128:timm13
uniprot id: A0A669C9X2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8128:LOC100701731
gene id: 8128:LOC100701731
uniprot id: I3JDK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

8128:otulin
gene id: 8128:otulin
uniprot id: I3JFW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

8128:yipf4
gene id: 8128:yipf4
uniprot id: A0A669C4D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

8128:mcmbp
gene id: 8128:mcmbp
uniprot id: A0A669B9B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCMBP family.
messages: Nucleus

8128:ndufb6
gene id: 8128:ndufb6
uniprot id: I3KLX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8128:serpini1
gene id: 8128:serpini1
uniprot id: A0A669EZW1
names: Similarity
messages: Belongs to the serpin family.

8128:LOC100695592
gene id: 8128:LOC100695592
uniprot id: A0A669C4W3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

8128:LOC100710946
gene id: 8128:LOC100710946
uniprot id: A0A669DKK5
names: Similarity
messages: Belongs to the folate receptor family.

8128:elavl2
gene id: 8128:elavl2
uniprot id: A0A669DHC6
names: Similarity
messages: Belongs to the RRM elav family.

8128:LOC100706597
gene id: 8128:LOC100706597
uniprot id: I3IWU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8128:LOC100704187
gene id: 8128:LOC100704187
uniprot id: A0A669C9Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8128:LOC100705338
gene id: 8128:LOC100705338
uniprot id: I3IY37
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8128:LOC100693084
gene id: 8128:LOC100693084
uniprot id: I3J9J5
names: Function
messages: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

8128:LOC102080023
gene id: 8128:LOC102080023
uniprot id: A0A669EWH4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100691584
gene id: 8128:LOC100691584
uniprot id: I3J5D4
names: Subcellular Location Annotation
messages: extracellular space

8128:ppcs
gene id: 8128:ppcs
uniprot id: I3J7V0
names: Similarity
messages: Belongs to the PPC synthetase family.

8128:slco2a1
gene id: 8128:slco2a1
uniprot id: A0A669FAW0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:chmp4b
gene id: 8128:chmp4b
uniprot id: I3J0N1
names: Similarity
messages: Belongs to the SNF7 family.

8128:htr2a
gene id: 8128:htr2a
uniprot id: I3KGY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

8128:mccc2
gene id: 8128:mccc2
uniprot id: A0A669BL41
names: Similarity
messages: Belongs to the AccD/PCCB family.

8128:LOC100699941
gene id: 8128:LOC100699941
uniprot id: I7INU7
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8128:LOC100710935
gene id: 8128:LOC100710935
uniprot id: I3JVP3
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

8128:LOC100708987
gene id: 8128:LOC100708987
uniprot id: I3K7D2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

8128:atp8b2
gene id: 8128:atp8b2
uniprot id: A0A669BDV1
uniprot id: I3JG82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8128:LOC100534422
gene id: 8128:LOC100534422
uniprot id: I3JA93
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100708797
gene id: 8128:LOC100708797
uniprot id: I3JHI1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8128:gatad1
gene id: 8128:gatad1
uniprot id: I3J2W8
names: Subcellular Location Annotation
messages: Nucleus

8128:lrig3
gene id: 8128:lrig3
uniprot id: A0A669CGF3
uniprot id: A0A669E2Y5
names: Subcellular Location Annotation
messages: Membrane

8128:kitlg
gene id: 8128:kitlg
uniprot id: I3J7P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Secreted
messages: filopodium
messages: lamellipodium

8128:LOC100693678
gene id: 8128:LOC100693678
uniprot id: A0A669CAP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola
messages: sarcolemma

8128:cpq
gene id: 8128:cpq
uniprot id: A0A669DW22
names: Subcellular Location Annotation
names: Subunit
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome
messages: Secreted

8128:rbm22
gene id: 8128:rbm22
uniprot id: I3K5L6
names: Similarity
messages: Belongs to the SLT11 family.

8128:LOC100704979
gene id: 8128:LOC100704979
uniprot id: I3JGI1
names: Similarity
messages: Belongs to the S-100 family.

8128:star
gene id: 8128:star
uniprot id: A0A669BH14
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

8128:lrit1
gene id: 8128:lrit1
uniprot id: I3KGH9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100704722
gene id: 8128:LOC100704722
uniprot id: I3JIL9
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100704254
gene id: 8128:LOC100704254
uniprot id: A0A669BU98
uniprot id: A0A669EET8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8128:hbp1
gene id: 8128:hbp1
uniprot id: I3JPC3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

8128:gpat4
gene id: 8128:gpat4
uniprot id: I3K0L0
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:LOC100695886
gene id: 8128:LOC100695886
uniprot id: I3JUN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.
messages: extracellular space

8128:canx
gene id: 8128:canx
uniprot id: A0A669E4A1
names: Similarity
messages: Belongs to the calreticulin family.

8128:LOC109204946
gene id: 8128:LOC109204946
uniprot id: A0A669EJ06
names: Subcellular Location Annotation
messages: Nucleus

8128:rpl4
gene id: 8128:rpl4
uniprot id: A0A669EI79
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

8128:LOC100698042
gene id: 8128:LOC100698042
uniprot id: I3JJ67
names: Subcellular Location Annotation
messages: Membrane

8128:tsr3
gene id: 8128:tsr3
uniprot id: I3KVK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100694613
gene id: 8128:LOC100694613
uniprot id: I3JYF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

8128:scube1
gene id: 8128:scube1
uniprot id: I3K1V8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:nkx1-2
gene id: 8128:nkx1-2
uniprot id: I3IVN2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100700357
gene id: 8128:LOC100700357
uniprot id: I3JPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

8128:hapln4
gene id: 8128:hapln4
uniprot id: I3J2L6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100691791
gene id: 8128:LOC100691791
uniprot id: A0A669CBW4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC100693999
gene id: 8128:LOC100693999
uniprot id: I3K5J7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

8128:kiaa1324
gene id: 8128:kiaa1324
uniprot id: A0A669C5M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

8128:gpr158
gene id: 8128:gpr158
uniprot id: A0A669CB70
uniprot id: I3JGY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8128:thyn1
gene id: 8128:thyn1
uniprot id: I3JYR7
names: Function
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

8128:pqlc2
gene id: 8128:pqlc2
uniprot id: I3JRY8
names: Subcellular Location Annotation
messages: Membrane

8128:ndufaf2
gene id: 8128:ndufaf2
uniprot id: I3KD19
names: Similarity
messages: Belongs to the complex I NDUFA12 subunit family.

8128:mlf2
gene id: 8128:mlf2
uniprot id: A0A669BN71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

8128:mtr
gene id: 8128:mtr
uniprot id: A0A669DDS2
uniprot id: I3JJQ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
messages: Cytoplasm
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

8128:ppm1a
gene id: 8128:ppm1a
uniprot id: I3KW50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8128:matk
gene id: 8128:matk
uniprot id: A0A669EYC7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:LOC100691490
gene id: 8128:LOC100691490
uniprot id: I3KZS5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100697795
gene id: 8128:LOC100697795
uniprot id: I3K3I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:nt5c2
gene id: 8128:nt5c2
uniprot id: I3KRG2
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

8128:tekt4
gene id: 8128:tekt4
uniprot id: I3KMD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8128:mindy1
gene id: 8128:mindy1
uniprot id: I3J7Y4
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

8128:c6
gene id: 8128:c6
uniprot id: I3K4N1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100699720
gene id: 8128:LOC100699720
uniprot id: A0A669CZC5
names: Similarity
messages: Belongs to the DOCK family.

8128:LOC100693003
gene id: 8128:LOC100693003
uniprot id: I3JFF4
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100700099
gene id: 8128:LOC100700099
uniprot id: I3JMZ1
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

8128:hnrnpu
gene id: 8128:hnrnpu
uniprot id: I3IY99
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100704147
gene id: 8128:LOC100704147
uniprot id: A0A669D0U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:polr2c
gene id: 8128:polr2c
uniprot id: I3JXY7
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

8128:acadsb
gene id: 8128:acadsb
uniprot id: A0A669FCE4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8128:LOC100693128
gene id: 8128:LOC100693128
uniprot id: I3KUB3
names: Similarity
messages: Belongs to the TGF-beta family.

8128:opn3
gene id: 8128:opn3
uniprot id: A0A669FA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8128:vwa1
gene id: 8128:vwa1
uniprot id: I3KRT4
names: Subcellular Location Annotation
messages: Membrane
messages: basement membrane

8128:LOC100704278
gene id: 8128:LOC100704278
uniprot id: I3JTA8
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:pde11a
gene id: 8128:pde11a
uniprot id: A0A669B681
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC100698339
gene id: 8128:LOC100698339
uniprot id: A0A669BXU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
messages: Interacts with ARMC12 in a TBC1D21-dependent manner.
messages: Mitochondrion outer membrane

8128:LOC100706517
gene id: 8128:LOC100706517
uniprot id: A0A669B7B4
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100703020
gene id: 8128:LOC100703020
uniprot id: I3KTD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8128:bcam
gene id: 8128:bcam
uniprot id: A0A669C0I8
uniprot id: I3KGV9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693612
gene id: 8128:LOC100693612
uniprot id: I3JGK2
names: Subcellular Location Annotation
messages: Membrane
messages: chromaffin granule membrane

8128:gad2
gene id: 8128:gad2
uniprot id: A0A669EXH4
uniprot id: I3JGU9
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8128:LOC102075508
gene id: 8128:LOC102075508
uniprot id: I3IU44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8128:rbm15
gene id: 8128:rbm15
uniprot id: I3J2T0
names: Similarity
messages: Belongs to the RRM Spen family.

8128:LOC100709096
gene id: 8128:LOC100709096
uniprot id: A0A669D3M3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100711709
gene id: 8128:LOC100711709
uniprot id: A0A669DHD0
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100700585
gene id: 8128:LOC100700585
uniprot id: A0A669B8B6
names: Similarity
messages: Belongs to the arrestin family.

8128:tmem121b
gene id: 8128:tmem121b
uniprot id: I3K9J8
names: Similarity
messages: Belongs to the TMEM121 family.

8128:ehhadh
gene id: 8128:ehhadh
uniprot id: A0A669C244
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

8128:LOC100691795
gene id: 8128:LOC100691795
uniprot id: A0A669BFE5
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

8128:LOC100704008
gene id: 8128:LOC100704008
uniprot id: A0A669F7V3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100692766
gene id: 8128:LOC100692766
uniprot id: A0A669EJG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

8128:LOC100710151
gene id: 8128:LOC100710151
uniprot id: A0A669EDI5
names: Function
messages: Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.

8128:rhpn2
gene id: 8128:rhpn2
uniprot id: A0A669DJ65
names: Similarity
messages: Belongs to the RHPN family.

8128:LOC100707311
gene id: 8128:LOC100707311
uniprot id: I3J3I7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8128:LOC100695265
gene id: 8128:LOC100695265
uniprot id: A0A669F0D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

8128:LOC100709554
gene id: 8128:LOC100709554
uniprot id: I3KQA7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC100701316
gene id: 8128:LOC100701316
uniprot id: I3KXM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

8128:znf622
gene id: 8128:znf622
uniprot id: I3K3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

8128:LOC109194326
gene id: 8128:LOC109194326
uniprot id: I3JTM0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:LOC100693469
gene id: 8128:LOC100693469
uniprot id: I3KK62
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:rogdi
gene id: 8128:rogdi
uniprot id: A0A669DMN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Perikaryon
messages: Presynapse
messages: synaptic vesicle

8128:agpat3
gene id: 8128:agpat3
uniprot id: I3J9G4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:LOC100697564
gene id: 8128:LOC100697564
uniprot id: I3KVV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8128:alx1
gene id: 8128:alx1
uniprot id: I3J7J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8128:KEH09 p13
gene id: 8128:KEH09_p13
uniprot id: D2KP24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

8128:cyp1b1
gene id: 8128:cyp1b1
uniprot id: A0A669CWV0
uniprot id: F8TAE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8128:LOC100704156
gene id: 8128:LOC100704156
uniprot id: I3KM26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

8128:chd4
gene id: 8128:chd4
uniprot id: I3K597
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8128:LOC100696189
gene id: 8128:LOC100696189
uniprot id: I3K3E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8128:LOC102083186
gene id: 8128:LOC102083186
uniprot id: A0A669EEK5
names: Similarity
messages: Belongs to the KHDC4 family.

8128:med19
gene id: 8128:med19
uniprot id: A0A669EPL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8128:LOC100712358
gene id: 8128:LOC100712358
uniprot id: A0A669CBJ4
uniprot id: A0A669DTW1
uniprot id: I3JNC8
names: Similarity
messages: Belongs to the TOM1 family.

8128:LOC100700719
gene id: 8128:LOC100700719
uniprot id: I3KTP0
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8128:sstr3
gene id: 8128:sstr3
uniprot id: I3K8H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:kiaa2013
gene id: 8128:kiaa2013
uniprot id: I3KNG1
names: Subcellular Location Annotation
messages: Membrane

8128:tubg1
gene id: 8128:tubg1
uniprot id: I3IY83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.
messages: centrosome

8128:tlr7
gene id: 8128:tlr7
uniprot id: I3KXY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8128:esam
gene id: 8128:esam
uniprot id: A0A669BSA8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690442
gene id: 8128:LOC100690442
uniprot id: I3K5Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

8128:neo1
gene id: 8128:neo1
uniprot id: I3JEC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. DCC family.
messages: Membrane

8128:setd6
gene id: 8128:setd6
uniprot id: A0A669BKK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: Protein-lysine N-methyltransferase.

8128:LOC100710753
gene id: 8128:LOC100710753
uniprot id: A0A669EP07
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8128:LOC100693397
gene id: 8128:LOC100693397
uniprot id: A0A669D6B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion inner membrane

8128:LOC100690581
gene id: 8128:LOC100690581
uniprot id: I3JFB3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100696448
gene id: 8128:LOC100696448
uniprot id: I3J5U3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100701127
gene id: 8128:LOC100701127
uniprot id: I3KRQ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8128:loxhd1
gene id: 8128:loxhd1
uniprot id: I3JKU1
uniprot id: I3KDI6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:gjd2
gene id: 8128:gjd2
uniprot id: A0A669F8F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:LOC100696172
gene id: 8128:LOC100696172
uniprot id: A0A669EKX1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:cdk5
gene id: 8128:cdk5
uniprot id: I3JSU3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:noc2l
gene id: 8128:noc2l
uniprot id: I3J2B3
names: Similarity
messages: Belongs to the NOC2 family.

8128:cers5
gene id: 8128:cers5
uniprot id: A0A669B980
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8128:atg2b
gene id: 8128:atg2b
uniprot id: I3KWB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

8128:slc25a46
gene id: 8128:slc25a46
uniprot id: A0A669EIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

8128:LOC100692869
gene id: 8128:LOC100692869
uniprot id: I3JTA0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100703912
gene id: 8128:LOC100703912
uniprot id: A0A669CMX6
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8128:emc6
gene id: 8128:emc6
uniprot id: I3KYH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:pnrc2
gene id: 8128:pnrc2
uniprot id: I3KZ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNRC family. PNRC2 subfamily.
messages: Nucleus
messages: P-body

8128:LOC100694981
gene id: 8128:LOC100694981
uniprot id: I3JIB6
names: Similarity
messages: Belongs to the NLRP family.

8128:folh1b
gene id: 8128:folh1b
uniprot id: I3JC87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100699058
gene id: 8128:LOC100699058
uniprot id: A0A669CR83
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

8128:LOC100690116
gene id: 8128:LOC100690116
uniprot id: I3J5S8
names: Subcellular Location Annotation
messages: Membrane

8128:eif2ak3
gene id: 8128:eif2ak3
uniprot id: I3K318
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

8128:ttll9
gene id: 8128:ttll9
uniprot id: I3J1P3
names: Similarity
messages: Belongs to the tubulin--tyrosine ligase family.

8128:LOC102079572
gene id: 8128:LOC102079572
uniprot id: A0A669B6U2
names: Subcellular Location Annotation
messages: Nucleus

8128:syk
gene id: 8128:syk
uniprot id: I3JZ29
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

8128:arap2
gene id: 8128:arap2
uniprot id: I3JS02
names: Subcellular Location Annotation
messages: Cytoplasm

8128:capzb
gene id: 8128:capzb
uniprot id: A0A669DIZ3
uniprot id: A0A669E3D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

8128:LOC100694900
gene id: 8128:LOC100694900
uniprot id: I3J926
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

8128:LOC100705111
gene id: 8128:LOC100705111
uniprot id: I3J3A4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100705319
gene id: 8128:LOC100705319
uniprot id: A0A669BNG6
uniprot id: A0A669BNJ8
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

8128:LOC100693325
gene id: 8128:LOC100693325
uniprot id: A0A669ECK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

8128:kcnk18
gene id: 8128:kcnk18
uniprot id: A0A669BJJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:tmed10
gene id: 8128:tmed10
uniprot id: I3KDK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100707345
gene id: 8128:LOC100707345
uniprot id: I3JA66
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:yars
gene id: 8128:yars
uniprot id: I3KE30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus

8128:fbln5
gene id: 8128:fbln5
uniprot id: I3KU95
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:ccni
gene id: 8128:ccni
uniprot id: I3K4C0
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

8128:pms1
gene id: 8128:pms1
uniprot id: I3JJJ1
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

8128:LOC100709718
gene id: 8128:LOC100709718
uniprot id: A0A669C349
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

8128:LOC100706723
gene id: 8128:LOC100706723
uniprot id: I3IY14
names: Similarity
messages: Belongs to the serpin family.

8128:LOC100706314
gene id: 8128:LOC100706314
uniprot id: A0A669CBG5
names: Subcellular Location Annotation
messages: extracellular space

8128:psmd13
gene id: 8128:psmd13
uniprot id: I3KER8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

8128:clcn5
gene id: 8128:clcn5
uniprot id: A0A669BLH8
uniprot id: A0A669EXX0
uniprot id: I3JIN3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100700294
gene id: 8128:LOC100700294
uniprot id: I3KHF6
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8128:LOC100691234
gene id: 8128:LOC100691234
uniprot id: A0A669DD04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100705019
gene id: 8128:LOC100705019
uniprot id: I3JV81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:ncor2
gene id: 8128:ncor2
uniprot id: I3JY88
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

8128:col4a1
gene id: 8128:col4a1
uniprot id: I3KA93
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

8128:shox2
gene id: 8128:shox2
uniprot id: I3JFQ5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100695766
gene id: 8128:LOC100695766
uniprot id: I3KUL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8128:LOC100702838
gene id: 8128:LOC100702838
uniprot id: I3KBY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:myf6
gene id: 8128:myf6
uniprot id: I6W5B2
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8128:stx17
gene id: 8128:stx17
uniprot id: A0A669FBQ7
names: Similarity
messages: Belongs to the syntaxin family.

8128:LOC100702368
gene id: 8128:LOC100702368
uniprot id: A0A669C5A7
uniprot id: A0A669D0B8
uniprot id: I3JL02
names: Subcellular Location Annotation
messages: extracellular space

8128:arglu1
gene id: 8128:arglu1
uniprot id: A0A669BQ12
names: Similarity
messages: Belongs to the UPF0430 family.

8128:LOC100705836
gene id: 8128:LOC100705836
uniprot id: I3IWJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

8128:pskh1
gene id: 8128:pskh1
uniprot id: I3JYQ1
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:proca1
gene id: 8128:proca1
uniprot id: A0A669F4X9
names: Subcellular Location Annotation
messages: Secreted

8128:prpf38a
gene id: 8128:prpf38a
uniprot id: I3JLV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

8128:tex10
gene id: 8128:tex10
uniprot id: I3JFH1
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

8128:LOC100697138
gene id: 8128:LOC100697138
uniprot id: I3IXG6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:LOC100691633
gene id: 8128:LOC100691633
uniprot id: I3KN35
names: Similarity
messages: Belongs to the SUA5 family.

8128:svopl
gene id: 8128:svopl
uniprot id: A0A669CBH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8128:has2
gene id: 8128:has2
uniprot id: A0A669E932
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NodC/HAS family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane

8128:prkaa2
gene id: 8128:prkaa2
uniprot id: A0A0M4FMJ6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

8128:LOC100700925
gene id: 8128:LOC100700925
uniprot id: A0A669CJS8
uniprot id: A0A669F1W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:LOC109194552
gene id: 8128:LOC109194552
uniprot id: A0A669DR22
names: Subcellular Location Annotation
messages: Membrane

8128:nudt6
gene id: 8128:nudt6
uniprot id: A0A669DCI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

8128:LOC100699250
gene id: 8128:LOC100699250
uniprot id: A0A669EI02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

8128:casp2
gene id: 8128:casp2
uniprot id: A0A669EF93
uniprot id: I3K506
uniprot id: I3K507
names: Similarity
messages: Belongs to the peptidase C14A family.

8128:p2rx1
gene id: 8128:p2rx1
uniprot id: A0A669DTB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8128:zic5
gene id: 8128:zic5
uniprot id: A0A669EBT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

8128:serping1
gene id: 8128:serping1
uniprot id: F6MDM1
names: Similarity
messages: Belongs to the serpin family.

8128:LOC100695248
gene id: 8128:LOC100695248
uniprot id: I3JIE9
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100690753
gene id: 8128:LOC100690753
uniprot id: I3KQ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8128:LOC100701166
gene id: 8128:LOC100701166
uniprot id: A0A669DDE4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100711349
gene id: 8128:LOC100711349
uniprot id: A0A669D345
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:bbs4
gene id: 8128:bbs4
uniprot id: I3JEC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

8128:slitrk5
gene id: 8128:slitrk5
uniprot id: I3KYX3
names: Similarity
messages: Belongs to the SLITRK family.

8128:LOC102080969
gene id: 8128:LOC102080969
uniprot id: I3JIP5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:optn
gene id: 8128:optn
uniprot id: I3K179
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Endosome
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

8128:LOC102076963
gene id: 8128:LOC102076963
uniprot id: A0A669F968
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:gna12
gene id: 8128:gna12
uniprot id: I3J5G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

8128:hacd1
gene id: 8128:hacd1
uniprot id: I3JFK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:ano5
gene id: 8128:ano5
uniprot id: I3JNH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100707932
gene id: 8128:LOC100707932
uniprot id: I3JGC1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:adgrl2
gene id: 8128:adgrl2
uniprot id: A0A669DRC8
uniprot id: I3J3C5
names: Subcellular Location Annotation
messages: Membrane

8128:lsr
gene id: 8128:lsr
uniprot id: A0A669B8D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8128:sugct
gene id: 8128:sugct
uniprot id: A0A669F4S0
names: Similarity
messages: Belongs to the CoA-transferase III family.

8128:LOC100699061
gene id: 8128:LOC100699061
uniprot id: I3KAF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC100708410
gene id: 8128:LOC100708410
uniprot id: A0A669EB45
names: Subcellular Location Annotation
messages: extracellular space

8128:ralb
gene id: 8128:ralb
uniprot id: I3J997
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8128:tmem163
gene id: 8128:tmem163
uniprot id: I3K1Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: May bind zinc and other divalent cations and recruit them to vesicular organelles.
messages: Membrane
messages: synaptic vesicle membrane

8128:LOC100701248
gene id: 8128:LOC100701248
uniprot id: I3KI88
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100711955
gene id: 8128:LOC100711955
uniprot id: I3J4N8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:galnt13
gene id: 8128:galnt13
uniprot id: A0A669CGN5
uniprot id: I3JQZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100698647
gene id: 8128:LOC100698647
uniprot id: I3KVJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:pi4ka
gene id: 8128:pi4ka
uniprot id: I3KA81
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8128:LOC100694337
gene id: 8128:LOC100694337
uniprot id: I3JP55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:ptges
gene id: 8128:ptges
uniprot id: I3JZA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

8128:LOC100705502
gene id: 8128:LOC100705502
uniprot id: I3J655
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:pdcd4
gene id: 8128:pdcd4
uniprot id: A0A669B025
names: Similarity
messages: Belongs to the PDCD4 family.

8128:LOC100700332
gene id: 8128:LOC100700332
uniprot id: A0A669BMZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

8128:lyrm1
gene id: 8128:lyrm1
uniprot id: A0A669C2I4
names: Similarity
messages: Belongs to the complex I LYR family.

8128:popdc2
gene id: 8128:popdc2
uniprot id: A0A669F723
names: Similarity
messages: Belongs to the popeye family.

8128:allc
gene id: 8128:allc
uniprot id: A0A669BKV5
names: Similarity
messages: Belongs to the allantoicase family.

8128:plac8l1
gene id: 8128:plac8l1
uniprot id: A0A669F7W0
names: Similarity
messages: Belongs to the cornifelin family.

8128:mterf3
gene id: 8128:mterf3
uniprot id: I3J2V2
names: Similarity
messages: Belongs to the mTERF family.

8128:LOC100704864
gene id: 8128:LOC100704864
uniprot id: I3JT23
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100698172
gene id: 8128:LOC100698172
uniprot id: A0A669DSU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-2-microglobulin family.
messages: Secreted

8128:LOC100694535
gene id: 8128:LOC100694535
uniprot id: A0A669BUY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

8128:htr5a
gene id: 8128:htr5a
uniprot id: A0A669DM17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:ppia
gene id: 8128:ppia
uniprot id: I3K035
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8128:LOC100704454
gene id: 8128:LOC100704454
uniprot id: I3KBG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

8128:LOC102078515
gene id: 8128:LOC102078515
uniprot id: I3K281
names: Similarity
messages: Belongs to the NLRP family.

8128:LOC100703480
gene id: 8128:LOC100703480
uniprot id: I3J9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8128:fam234a
gene id: 8128:fam234a
uniprot id: I3KVG4
names: Similarity
messages: Belongs to the FAM234 family.

8128:pdss2
gene id: 8128:pdss2
uniprot id: I3KTY7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8128:LOC100697636
gene id: 8128:LOC100697636
uniprot id: A0A669C0Q5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

8128:rpia
gene id: 8128:rpia
uniprot id: A0A669EJ33
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

8128:ogt
gene id: 8128:ogt
uniprot id: I3KN03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

8128:rhbdf2
gene id: 8128:rhbdf2
uniprot id: I3KPE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

8128:LOC100712440
gene id: 8128:LOC100712440
uniprot id: A0A669D3G8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:gnmt
gene id: 8128:gnmt
uniprot id: I3JNF6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.

8128:rfx3
gene id: 8128:rfx3
uniprot id: I3K946
names: Subcellular Location Annotation
messages: Nucleus

8128:mindy4
gene id: 8128:mindy4
uniprot id: I3IZY2
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

8128:camsap2
gene id: 8128:camsap2
uniprot id: I3K3U5
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8128:usp7
gene id: 8128:usp7
uniprot id: I3KF52
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:usp48
gene id: 8128:usp48
uniprot id: I3JQ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

8128:gipc2
gene id: 8128:gipc2
uniprot id: I3KPZ0
names: Similarity
messages: Belongs to the GIPC family.

8128:LOC100694377
gene id: 8128:LOC100694377
uniprot id: A0A669CQ87
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8128:LOC100691200
gene id: 8128:LOC100691200
uniprot id: I3K5F4
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8128:LOC100692260
gene id: 8128:LOC100692260
uniprot id: I3JGG5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8128:LOC100704239
gene id: 8128:LOC100704239
uniprot id: I3IVV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8128:LOC100702351
gene id: 8128:LOC100702351
uniprot id: I3KSN6
names: Similarity
messages: Belongs to the DPH3 family.

8128:LOC100710962
gene id: 8128:LOC100710962
uniprot id: I3J3U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

8128:LOC100699793
gene id: 8128:LOC100699793
uniprot id: A0A669FAH6
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100693976
gene id: 8128:LOC100693976
uniprot id: A0A669CA13
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a role in the process of neurogenesis.

8128:man2c1
gene id: 8128:man2c1
uniprot id: I3KDZ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

8128:LOC100706625
gene id: 8128:LOC100706625
uniprot id: A0A669BH10
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8128:LOC100697052
gene id: 8128:LOC100697052
uniprot id: I3KFY8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

8128:LOC100705876
gene id: 8128:LOC100705876
uniprot id: I3JKW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

8128:copa
gene id: 8128:copa
uniprot id: I3KDA2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

8128:LOC100705094
gene id: 8128:LOC100705094
uniprot id: I3JVX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8128:fam171a2
gene id: 8128:fam171a2
uniprot id: I3KNZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

8128:LOC100697816
gene id: 8128:LOC100697816
uniprot id: I3JJY7
names: Subcellular Location Annotation
messages: Nucleus

8128:vcp
gene id: 8128:vcp
uniprot id: I3K7U2
names: Similarity
messages: Belongs to the AAA ATPase family.

8128:e2f3
gene id: 8128:e2f3
uniprot id: I3JJ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8128:LOC100700473
gene id: 8128:LOC100700473
uniprot id: A0A669CPX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:swi5
gene id: 8128:swi5
uniprot id: A0A669BTQ7
names: Function
names: Similarity
messages: Belongs to the SWI5/SAE3 family.
messages: Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.

8128:LOC100704599
gene id: 8128:LOC100704599
uniprot id: A0A669EGQ0
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

8128:glyctk
gene id: 8128:glyctk
uniprot id: I3J7Z1
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

8128:rin2
gene id: 8128:rin2
uniprot id: A0A669B512
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

8128:dhodh
gene id: 8128:dhodh
uniprot id: A0A669BQU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

8128:slain1
gene id: 8128:slain1
uniprot id: A0A669F141
uniprot id: I3JHZ0
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

8128:LOC100705437
gene id: 8128:LOC100705437
uniprot id: A0A669E6W7
uniprot id: I3JAR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8128:LOC100708305
gene id: 8128:LOC100708305
uniprot id: A0A669DWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8128:uso1
gene id: 8128:uso1
uniprot id: A0A669CA01
uniprot id: A0A669E2K0
uniprot id: A0A669EZX8
uniprot id: I3KLL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VDP/USO1/EDE1 family.
messages: Membrane

8128:gnl2
gene id: 8128:gnl2
uniprot id: I3KHB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

8128:klhl15
gene id: 8128:klhl15
uniprot id: A0A669C4H7
uniprot id: A0A669F407
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100704944
gene id: 8128:LOC100704944
uniprot id: A0A669EIQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

8128:rnpc3
gene id: 8128:rnpc3
uniprot id: I3JAW2
names: Subcellular Location Annotation
messages: Nucleus

8128:serpind1
gene id: 8128:serpind1
uniprot id: I3KA95
names: Similarity
messages: Belongs to the serpin family.

8128:apip
gene id: 8128:apip
uniprot id: A0A669D747
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
messages: Cytoplasm

8128:LOC100709242
gene id: 8128:LOC100709242
uniprot id: I3J2J9
names: Similarity
messages: Belongs to the EPS8 family.

8128:LOC100711490
gene id: 8128:LOC100711490
uniprot id: I3KGU6
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8128:cmtm7
gene id: 8128:cmtm7
uniprot id: I3J0U9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100691763
gene id: 8128:LOC100691763
uniprot id: I3J5T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8128:spry1
gene id: 8128:spry1
uniprot id: A0A669DY62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: Cytoplasm
messages: Membrane

8128:LOC100706516
gene id: 8128:LOC100706516
uniprot id: A0A669EST8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8128:amh
gene id: 8128:amh
uniprot id: A9XKS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

8128:podxl2
gene id: 8128:podxl2
uniprot id: A0A669EX78
names: Subcellular Location Annotation
messages: Membrane

8128:ssr1
gene id: 8128:ssr1
uniprot id: A0A669BBF9
uniprot id: I3KI17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

8128:LOC100697346
gene id: 8128:LOC100697346
uniprot id: A0A669BIH4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC106098755
gene id: 8128:LOC106098755
uniprot id: A0A669DJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

8128:rad9a
gene id: 8128:rad9a
uniprot id: I3JC67
names: Similarity
messages: Belongs to the rad9 family.

8128:LOC100712163
gene id: 8128:LOC100712163
uniprot id: I3JUT4
names: Similarity
messages: Belongs to the cullin family.

8128:LOC100697176
gene id: 8128:LOC100697176
uniprot id: I3KGR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8128:LOC100700271
gene id: 8128:LOC100700271
uniprot id: A0A669DUN8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

8128:LOC109196670
gene id: 8128:LOC109196670
uniprot id: I3JLA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC100705688
gene id: 8128:LOC100705688
uniprot id: I3K2A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

8128:elk4
gene id: 8128:elk4
uniprot id: I3J5L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:LOC100704973
gene id: 8128:LOC100704973
uniprot id: I3JRV0
names: Similarity
messages: Belongs to the SZRD1 family.

8128:LOC100711438
gene id: 8128:LOC100711438
uniprot id: I3IYI4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell junction
messages: Cell membrane
messages: Membrane

8128:LOC100702930
gene id: 8128:LOC100702930
uniprot id: A0A669EKG9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

8128:taf6
gene id: 8128:taf6
uniprot id: A0A669CHK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

8128:plagl2
gene id: 8128:plagl2
uniprot id: I3IVG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

8128:LOC100692148
gene id: 8128:LOC100692148
uniprot id: I3KGF1
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC106098467
gene id: 8128:LOC106098467
uniprot id: A0A669D6W8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:nfyb
gene id: 8128:nfyb
uniprot id: I3K1U3
names: Function
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.

8128:aldh4a1
gene id: 8128:aldh4a1
uniprot id: A0A669DC66
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8128:spr
gene id: 8128:spr
uniprot id: I3K460
names: Similarity
messages: Belongs to the sepiapterin reductase family.

8128:nkiras2
gene id: 8128:nkiras2
uniprot id: A0A669CSH4
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

8128:tmem255b
gene id: 8128:tmem255b
uniprot id: I3J533
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

8128:mtif2
gene id: 8128:mtif2
uniprot id: A0A669CNG6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

8128:sf3a2
gene id: 8128:sf3a2
uniprot id: A0A669BZK8
names: Similarity
messages: Belongs to the SF3A2 family.

8128:LOC100695333
gene id: 8128:LOC100695333
uniprot id: I3K8U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

8128:smarcal1
gene id: 8128:smarcal1
uniprot id: I3JR70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
messages: Nucleus

8128:grhl3
gene id: 8128:grhl3
uniprot id: I3J6D4
names: Subcellular Location Annotation
messages: Nucleus

8128:ebp
gene id: 8128:ebp
uniprot id: I3K2X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100700946
gene id: 8128:LOC100700946
uniprot id: I3KDM7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:supt6h
gene id: 8128:supt6h
uniprot id: I3JDI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

8128:galnt15
gene id: 8128:galnt15
uniprot id: I3J9Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:chrna1
gene id: 8128:chrna1
uniprot id: I3JPR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100707936
gene id: 8128:LOC100707936
uniprot id: I3KQG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

8128:LOC100695287
gene id: 8128:LOC100695287
uniprot id: Q9I9I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

8128:zcchc17
gene id: 8128:zcchc17
uniprot id: A0A669D5G6
names: Subcellular Location Annotation
messages: nucleolus

8128:LOC100700725
gene id: 8128:LOC100700725
uniprot id: A0A669ERC6
names: Subcellular Location Annotation
messages: Cytoplasm

8128:naxe
gene id: 8128:naxe
uniprot id: I3K891
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Secreted

8128:gps1
gene id: 8128:gps1
uniprot id: A0A669DZS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN1 family.
messages: Cytoplasm
messages: Nucleus

8128:tmem183a
gene id: 8128:tmem183a
uniprot id: I3KT54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

8128:LOC102075686
gene id: 8128:LOC102075686
uniprot id: A0A669BN15
uniprot id: A0A669DD42
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100710977
gene id: 8128:LOC100710977
uniprot id: A0A669BB28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB5 displays a chymotrypsin-like activity.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8128:grina
gene id: 8128:grina
uniprot id: I3J2P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8128:LOC100707512
gene id: 8128:LOC100707512
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:smpd1
gene id: 8128:smpd1
uniprot id: I3JAU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

8128:LOC100705910
gene id: 8128:LOC100705910
uniprot id: A0A669BMC2
names: Similarity
messages: Belongs to the FAM53 family.

8128:LOC100705527
gene id: 8128:LOC100705527
uniprot id: I3KBJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100690935
gene id: 8128:LOC100690935
uniprot id: A0A669CAW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

8128:LOC100694776
gene id: 8128:LOC100694776
uniprot id: I3JAD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8128:dnajc2
gene id: 8128:dnajc2
uniprot id: A0A669C1Q6
names: Subcellular Location Annotation
messages: cytosol

8128:LOC100534555
gene id: 8128:LOC100534555
uniprot id: A0A669CG32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

8128:LOC100691120
gene id: 8128:LOC100691120
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:pde1a
gene id: 8128:pde1a
uniprot id: A0A669BEA3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC102080704
gene id: 8128:LOC102080704
uniprot id: I3J1Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

8128:LOC100691114
gene id: 8128:LOC100691114
uniprot id: I3KQ00
names: Subcellular Location Annotation
messages: Membrane

8128:LOC112841629
gene id: 8128:LOC112841629
uniprot id: I3JBU2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100705087
gene id: 8128:LOC100705087
uniprot id: A0A669E7E8
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:flot2
gene id: 8128:flot2
uniprot id: I3K4Q5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

8128:hadhb
gene id: 8128:hadhb
uniprot id: I3JDU8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8128:tmem192
gene id: 8128:tmem192
uniprot id: A0A669DA19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

8128:mks1
gene id: 8128:mks1
uniprot id: I3KLC4
names: Subcellular Location Annotation
messages: cilium basal body

8128:tmem200a
gene id: 8128:tmem200a
uniprot id: I3IWA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

8128:gpr161
gene id: 8128:gpr161
uniprot id: I3K9Z7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:nhej1
gene id: 8128:nhej1
uniprot id: I3K2G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

8128:otp
gene id: 8128:otp
uniprot id: I3KEB3
names: Subcellular Location Annotation
messages: Nucleus

8128:pepsin
gene id: 8128:pepsin
uniprot id: A0A669CL32
names: Similarity
messages: Belongs to the peptidase A1 family.

8128:tyrp1
gene id: 8128:tyrp1
uniprot id: I3JL18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

8128:rpl30
gene id: 8128:rpl30
uniprot id: I3J3A6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

8128:LOC100690263
gene id: 8128:LOC100690263
uniprot id: I3KRU5
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

8128:p2rx4
gene id: 8128:p2rx4
uniprot id: A0A669ELP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8128:rtf2
gene id: 8128:rtf2
uniprot id: I3JIB2
names: Similarity
messages: Belongs to the rtf2 family.

8128:LOC100703625
gene id: 8128:LOC100703625
uniprot id: I3J8N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: sarcolemma
messages: synaptosome

8128:LOC100711674
gene id: 8128:LOC100711674
uniprot id: I3J1E3
names: Similarity
messages: Belongs to the perilipin family.

8128:nkx3-2
gene id: 8128:nkx3-2
uniprot id: A0A669CKW2
names: Subcellular Location Annotation
messages: Nucleus

8128:eef2kmt
gene id: 8128:eef2kmt
uniprot id: I3JSQ2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.

8128:lipe
gene id: 8128:lipe
uniprot id: I3JZT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'GDXG' lipolytic enzyme family.
messages: Cell membrane
messages: Lipid droplet
messages: caveola
messages: cytosol

8128:LOC100534442
gene id: 8128:LOC100534442
uniprot id: B7SU45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8128:LOC100709964
gene id: 8128:LOC100709964
uniprot id: A0A669C4C8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:LOC100708442
gene id: 8128:LOC100708442
uniprot id: I3JYF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8128:LOC100709700
gene id: 8128:LOC100709700
uniprot id: I3J4S8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100697103
gene id: 8128:LOC100697103
uniprot id: A0A669ERN4
uniprot id: I3J9C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8128:LOC100702885
gene id: 8128:LOC100702885
uniprot id: I3JE12
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

8128:LOC100703546
gene id: 8128:LOC100703546
uniprot id: A0A669CJJ0
uniprot id: A0A669CWH6
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100711672
gene id: 8128:LOC100711672
uniprot id: A0A669BXB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

8128:fam160b1
gene id: 8128:fam160b1
uniprot id: I3JV87
names: Similarity
messages: Belongs to the FHIP family.

8128:LOC100690280
gene id: 8128:LOC100690280
uniprot id: A0A669EZ12
names: Similarity
messages: Belongs to the JAKMIP family.

8128:LOC109204746
gene id: 8128:LOC109204746
uniprot id: A0A669CIF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8128:LOC100711353
gene id: 8128:LOC100711353
uniprot id: A0A669EZE3
names: Similarity
messages: Belongs to the MHC class I family.

8128:LOC100712087
gene id: 8128:LOC100712087
uniprot id: I3KHX1
names: Subcellular Location Annotation
messages: Cytoplasm

8128:trub2
gene id: 8128:trub2
uniprot id: A0A669DMH6
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

8128:LOC100708495
gene id: 8128:LOC100708495
uniprot id: A0A669EWM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC100701554
gene id: 8128:LOC100701554
uniprot id: A0A669CSS1
uniprot id: A0A669D927
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8128:l3hypdh
gene id: 8128:l3hypdh
uniprot id: A0A669ECT5
names: Similarity
messages: Belongs to the proline racemase family.

8128:inip
gene id: 8128:inip
uniprot id: A0A669C3Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

8128:LOC100712187
gene id: 8128:LOC100712187
uniprot id: I3KT04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

8128:ncaph2
gene id: 8128:ncaph2
uniprot id: I3JKS2
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

8128:gria1
gene id: 8128:gria1
uniprot id: A0A669CG07
uniprot id: I3KM55
names: Subcellular Location Annotation
messages: Membrane

8128:smad7
gene id: 8128:smad7
uniprot id: I3JLL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100707567
gene id: 8128:LOC100707567
uniprot id: I3JY56
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: Perikaryon
messages: dendrite

8128:plk3
gene id: 8128:plk3
uniprot id: I3JUC8
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

8128:LOC100695679
gene id: 8128:LOC100695679
uniprot id: A0A669EWQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

8128:LOC100712211
gene id: 8128:LOC100712211
uniprot id: I3JD10
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100702341
gene id: 8128:LOC100702341
uniprot id: I3KTR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:tmem167b
gene id: 8128:tmem167b
uniprot id: A0A669BE92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100702742
gene id: 8128:LOC100702742
uniprot id: I3KZW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:mocos
gene id: 8128:mocos
uniprot id: A0A669CKF7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

8128:LOC100691430
gene id: 8128:LOC100691430
uniprot id: I3KKR0
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:met
gene id: 8128:met
uniprot id: A0A669F733
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:fkrp
gene id: 8128:fkrp
uniprot id: I3KXC8
names: Similarity
messages: Belongs to the LicD transferase family.

8128:LOC100692075
gene id: 8128:LOC100692075
uniprot id: A0A669FB58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8128:LOC100696753
gene id: 8128:LOC100696753
uniprot id: I3KXW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:LOC100705071
gene id: 8128:LOC100705071
uniprot id: I3KQK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.

8128:LOC100712188
gene id: 8128:LOC100712188
uniprot id: I3J8A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

8128:hdhd2
gene id: 8128:hdhd2
uniprot id: I3J8J5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

8128:renbp
gene id: 8128:renbp
uniprot id: A0A669BJT8
uniprot id: A0A669D0Q6
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

8128:rnf114
gene id: 8128:rnf114
uniprot id: I3KLI0
names: Subunit
messages: Interacts with XAF1, the interaction increases XAF1 stability and proapoptotic effects, and may regulate IFN signaling.

8128:tent5d
gene id: 8128:tent5d
uniprot id: A0A669E3M6
names: Similarity
messages: Belongs to the TENT family.

8128:LOC100691958
gene id: 8128:LOC100691958
uniprot id: I3JUB5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

8128:ufd1
gene id: 8128:ufd1
uniprot id: I3KAF4
names: Similarity
messages: Belongs to the UFD1 family.

8128:abracl
gene id: 8128:abracl
uniprot id: I3JE33
names: Similarity
messages: Belongs to the costars family.

8128:polr2e
gene id: 8128:polr2e
uniprot id: A0A669BQB6
uniprot id: I3J2R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

8128:msl3
gene id: 8128:msl3
uniprot id: I3K291
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100696147
gene id: 8128:LOC100696147
uniprot id: I3JHW2
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

8128:LOC100706341
gene id: 8128:LOC100706341
uniprot id: A0A669BEQ6
names: Similarity
messages: Belongs to the WD repeat EBI family.

8128:LOC102079986
gene id: 8128:LOC102079986
uniprot id: I3KS02
names: Similarity
messages: Belongs to the cornifelin family.

8128:LOC100705343
gene id: 8128:LOC100705343
uniprot id: I3L010
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:slc39a9
gene id: 8128:slc39a9
uniprot id: I3KUC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: May act as a zinc-influx transporter.
messages: Membrane

8128:LOC100705704
gene id: 8128:LOC100705704
uniprot id: I3K383
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola
messages: sarcomere

8128:clp1
gene id: 8128:clp1
uniprot id: I3JC09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

8128:bmp3
gene id: 8128:bmp3
uniprot id: I3K955
names: Similarity
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.

8128:LOC100696392
gene id: 8128:LOC100696392
uniprot id: A0A669CVX3
uniprot id: A0A669CZA3
uniprot id: A0A669F2F7
uniprot id: I3KB89
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
messages: Interacts with EF1A1, facilitates EF1A1 distribution to the membrane periphery and ruffles upon growth factor stimulation and suppresses cell migration.
messages: Membrane
messages: focal adhesion

8128:rps12
gene id: 8128:rps12
uniprot id: O13019
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

8128:LOC100704231
gene id: 8128:LOC100704231
uniprot id: A0A669AZ32
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8128:LOC100700412
gene id: 8128:LOC100700412
uniprot id: I3K0P5
names: Similarity
messages: Belongs to the PP2C family.

8128:LOC100705328
gene id: 8128:LOC100705328
uniprot id: A0A669ES37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100700918
gene id: 8128:LOC100700918
uniprot id: I3JS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

8128:LOC100692578
gene id: 8128:LOC100692578
uniprot id: I3JW74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

8128:LOC100711131
gene id: 8128:LOC100711131
uniprot id: A0A669CUW0
names: Similarity
messages: Belongs to the SPIN/STSY family.

8128:LOC100698302
gene id: 8128:LOC100698302
uniprot id: I3IX29
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8128:LOC100703725
gene id: 8128:LOC100703725
uniprot id: I3J881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:rfc1
gene id: 8128:rfc1
uniprot id: I3JR06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

8128:laptm4b
gene id: 8128:laptm4b
uniprot id: I3KHV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

8128:LOC100690941
gene id: 8128:LOC100690941
uniprot id: A0A669B149
uniprot id: A0A669FAD2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100689869
gene id: 8128:LOC100689869
uniprot id: A0A669CUJ8
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8128:LOC100690637
gene id: 8128:LOC100690637
uniprot id: A0A669BSC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8128:ell2
gene id: 8128:ell2
uniprot id: A0A669C0A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8128:LOC100700808
gene id: 8128:LOC100700808
uniprot id: A0A669BKY8
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8128:eif2b5
gene id: 8128:eif2b5
uniprot id: A0A669F1S9
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

8128:LOC102080925
gene id: 8128:LOC102080925
uniprot id: A0A669DM53
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690878
gene id: 8128:LOC100690878
uniprot id: I3KI83
names: Similarity
messages: Belongs to the NRAMP family.

8128:LOC100690502
gene id: 8128:LOC100690502
uniprot id: A0A669CBJ7
names: Subcellular Location Annotation
messages: Membrane

8128:pold3
gene id: 8128:pold3
uniprot id: I3KCU2
names: Subcellular Location Annotation
messages: Nucleus

8128:unc93b1
gene id: 8128:unc93b1
uniprot id: A0A669CXW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

8128:vopp1
gene id: 8128:vopp1
uniprot id: I3KD42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

8128:slc35a5
gene id: 8128:slc35a5
uniprot id: I3KHG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

8128:slc16a6
gene id: 8128:slc16a6
uniprot id: I3KV63
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100711823
gene id: 8128:LOC100711823
uniprot id: I3JTQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8128:LOC100699442
gene id: 8128:LOC100699442
uniprot id: A0A669F208
names: Subcellular Location Annotation
messages: Membrane

8128:ppp4r3b
gene id: 8128:ppp4r3b
uniprot id: A0A669D5I0
names: Similarity
messages: Belongs to the SMEK family.

8128:LOC100711224
gene id: 8128:LOC100711224
uniprot id: I3JQH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

8128:LOC100700371
gene id: 8128:LOC100700371
uniprot id: I3JN02
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100705156
gene id: 8128:LOC100705156
uniprot id: A0A669D320
names: Similarity
messages: Belongs to the SNF7 family.

8128:exosc2
gene id: 8128:exosc2
uniprot id: I3K9B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

8128:LOC100707990
gene id: 8128:LOC100707990
uniprot id: I3JBG0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:LOC100700879
gene id: 8128:LOC100700879
uniprot id: I3KJU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

8128:pde6d
gene id: 8128:pde6d
uniprot id: A0A669EGD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PDE6D/unc-119 family.
messages: Cytoplasmic vesicle membrane
messages: Interacts with the prenylated catalytic subunits of PDE6, an oligomer composed of two catalytic chains and two inhibitory chains; has no effect on enzyme activity but promotes the release of the prenylated enzyme from cell membrane.
messages: Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
messages: cilium basal body
messages: cytosol

8128:epo
gene id: 8128:epo
uniprot id: A0A669AV42
uniprot id: I3KVB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
messages: Secreted

8128:ndufs3
gene id: 8128:ndufs3
uniprot id: I3JIT2
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

8128:cpne7
gene id: 8128:cpne7
uniprot id: A0A669EPU9
names: Similarity
messages: Belongs to the copine family.

8128:LOC100699976
gene id: 8128:LOC100699976
uniprot id: A0A669CDQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:chmp3
gene id: 8128:chmp3
uniprot id: I3KW69
names: Similarity
messages: Belongs to the SNF7 family.

8128:htr3b
gene id: 8128:htr3b
uniprot id: I3JSS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

8128:tpp1
gene id: 8128:tpp1
uniprot id: I3KW36
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100696175
gene id: 8128:LOC100696175
uniprot id: I3J1C8
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100701007
gene id: 8128:LOC100701007
uniprot id: A0A669EJG7
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

8128:LOC100707601
gene id: 8128:LOC100707601
uniprot id: I3KDB1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100691440
gene id: 8128:LOC100691440
uniprot id: I3IXY7
names: Subcellular Location Annotation
messages: Nucleus

8128:ppie
gene id: 8128:ppie
uniprot id: I3JN36
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.

8128:pcnx3
gene id: 8128:pcnx3
uniprot id: I3JBK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

8128:emc4
gene id: 8128:emc4
uniprot id: A0A669B399
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC4 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100693441
gene id: 8128:LOC100693441
uniprot id: A0A669BX03
uniprot id: A0A669CQB4
uniprot id: A0A669CUG3
uniprot id: A0A669F5Y7
uniprot id: I3JVW2
names: Subcellular Location Annotation
messages: cytoskeleton

8128:slc5a3
gene id: 8128:slc5a3
uniprot id: I3KXY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8128:bcl2l1
gene id: 8128:bcl2l1
uniprot id: I3IZK7
names: Similarity
messages: Belongs to the Bcl-2 family.

8128:alas1
gene id: 8128:alas1
uniprot id: I3KAD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

8128:LOC102082980
gene id: 8128:LOC102082980
uniprot id: I3K353
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:wdfy1
gene id: 8128:wdfy1
uniprot id: I3KBF6
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8128:etv6
gene id: 8128:etv6
uniprot id: A0A669BTE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:tecr
gene id: 8128:tecr
uniprot id: A0A669EPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:ppp1r3b
gene id: 8128:ppp1r3b
uniprot id: I3K3N9
names: Subunit
messages: Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.

8128:LOC102077906
gene id: 8128:LOC102077906
uniprot id: A0A669BYH5
uniprot id: A0A669EBB0
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100691094
gene id: 8128:LOC100691094
uniprot id: A0A669F306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

8128:klhl3
gene id: 8128:klhl3
uniprot id: A0A669AW87
names: Subcellular Location Annotation
messages: cytoskeleton
messages: cytosol

8128:LOC100707158
gene id: 8128:LOC100707158
uniprot id: I3K4U7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasm
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: cilium

8128:fam189b
gene id: 8128:fam189b
uniprot id: I3JGK4
names: Similarity
messages: Belongs to the ENTREP family.

8128:ankrd13b
gene id: 8128:ankrd13b
uniprot id: A0A669C759
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

8128:LOC100699899
gene id: 8128:LOC100699899
uniprot id: I3K4X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8128:pou3f4
gene id: 8128:pou3f4
uniprot id: I3KXP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

8128:idi1
gene id: 8128:idi1
uniprot id: A0A669CU46
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

8128:LOC109195088
gene id: 8128:LOC109195088
uniprot id: A0A669AWN4
names: Similarity
messages: Belongs to the cornifelin family.

8128:LOC100690027
gene id: 8128:LOC100690027
uniprot id: A0A669FBX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8128:sema4d
gene id: 8128:sema4d
uniprot id: A0A669B596
uniprot id: A0A669F5K2
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100534483
gene id: 8128:LOC100534483
uniprot id: C9EIT1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

8128:cxcr5
gene id: 8128:cxcr5
uniprot id: I3L014
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:derl2
gene id: 8128:derl2
uniprot id: I3K0D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100691516
gene id: 8128:LOC100691516
uniprot id: A0A669F3N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8128:farsb
gene id: 8128:farsb
uniprot id: I3KYT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

8128:smad6
gene id: 8128:smad6
uniprot id: A0A669BL32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100696616
gene id: 8128:LOC100696616
uniprot id: I3KXI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

8128:rpl7
gene id: 8128:rpl7
uniprot id: A0A669C8W7
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

8128:LOC100704249
gene id: 8128:LOC100704249
uniprot id: I3KYU9
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100694966
gene id: 8128:LOC100694966
uniprot id: I3JAG6
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100690777
gene id: 8128:LOC100690777
uniprot id: I3KET3
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

8128:magi2
gene id: 8128:magi2
uniprot id: A0A669BFL7
uniprot id: A0A669FAI8
uniprot id: I3IU21
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100705257
gene id: 8128:LOC100705257
uniprot id: A0A669DVS1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100698940
gene id: 8128:LOC100698940
uniprot id: I3JPZ5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC100693853
gene id: 8128:LOC100693853
uniprot id: I3J2I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC102078210
gene id: 8128:LOC102078210
uniprot id: I3K489
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100690574
gene id: 8128:LOC100690574
uniprot id: A0A669BIK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

8128:usp1
gene id: 8128:usp1
uniprot id: I3JQG5
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:LOC109194237
gene id: 8128:LOC109194237
uniprot id: I3KKX0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:tp53inp2
gene id: 8128:tp53inp2
uniprot id: I3KLL2
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

8128:LOC100692580
gene id: 8128:LOC100692580
uniprot id: I3JUY5
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

8128:mal2
gene id: 8128:mal2
uniprot id: A0A669DUT9
names: Subcellular Location Annotation
messages: Membrane

8128:zc3h14
gene id: 8128:zc3h14
uniprot id: I3KDP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

8128:LOC100711653
gene id: 8128:LOC100711653
uniprot id: I3JN57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

8128:mms19
gene id: 8128:mms19
uniprot id: I3KUN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MET18/MMS19 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus
messages: spindle

8128:LOC100702381
gene id: 8128:LOC100702381
uniprot id: A0A669DEX5
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8128:LOC100696267
gene id: 8128:LOC100696267
uniprot id: I3J4U1
uniprot id: I3J4U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

8128:LOC100710726
gene id: 8128:LOC100710726
uniprot id: I3KKK3
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

8128:dyrk1a
gene id: 8128:dyrk1a
uniprot id: A0A669DJK8
uniprot id: A0A669F8G8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8128:LOC100711692
gene id: 8128:LOC100711692
uniprot id: A0A669CFN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

8128:mapkap1
gene id: 8128:mapkap1
uniprot id: I3JZE5
names: Similarity
messages: Belongs to the SIN1 family.

8128:far1
gene id: 8128:far1
uniprot id: A0A669C6G4
uniprot id: A0A669CM42
uniprot id: A0A669CUA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

8128:chpf
gene id: 8128:chpf
uniprot id: A0A669AYV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8128:slc35b4
gene id: 8128:slc35b4
uniprot id: A0A669D3J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

8128:LOC100712102
gene id: 8128:LOC100712102
uniprot id: I3JXF1
names: Similarity
messages: Belongs to the serpin family.

8128:stk11ip
gene id: 8128:stk11ip
uniprot id: I3K6P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

8128:LOC102075590
gene id: 8128:LOC102075590
uniprot id: I3L031
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100711633
gene id: 8128:LOC100711633
uniprot id: I3KK07
names: Subcellular Location Annotation
messages: extracellular space

8128:pycr3
gene id: 8128:pycr3
uniprot id: I3JY98
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

8128:mterf1
gene id: 8128:mterf1
uniprot id: I3KUX1
names: Similarity
messages: Belongs to the mTERF family.

8128:gje1
gene id: 8128:gje1
uniprot id: A0A669F581
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:cdc25b
gene id: 8128:cdc25b
uniprot id: I3K2Y9
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

8128:tmem132c
gene id: 8128:tmem132c
uniprot id: I3JY15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8128:LOC100702599
gene id: 8128:LOC100702599
uniprot id: I3JXL4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8128:LOC100704992
gene id: 8128:LOC100704992
uniprot id: I3KBH9
names: Similarity
messages: Belongs to the TAFA family.

8128:LOC100704366
gene id: 8128:LOC100704366
uniprot id: I3K755
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

8128:kcnk6
gene id: 8128:kcnk6
uniprot id: I3JLD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:ppm1k
gene id: 8128:ppm1k
uniprot id: I3KLK7
names: Similarity
messages: Belongs to the PP2C family.

8128:bpnt1
gene id: 8128:bpnt1
uniprot id: A0A669CZW8
uniprot id: A0A669DJ37
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8128:tm7sf3
gene id: 8128:tm7sf3
uniprot id: A0A669BLE5
names: Subcellular Location Annotation
messages: Membrane

8128:ubr3
gene id: 8128:ubr3
uniprot id: I3JQ82
uniprot id: I3JQ83
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

8128:LOC100694011
gene id: 8128:LOC100694011
uniprot id: I3JXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

8128:dph6
gene id: 8128:dph6
uniprot id: A0A669DL31
names: Similarity
messages: Belongs to the Diphthine--ammonia ligase family.

8128:aff4
gene id: 8128:aff4
uniprot id: I3JP24
names: Similarity
messages: Belongs to the AF4 family.

8128:rpl13a
gene id: 8128:rpl13a
uniprot id: A0A669DQ93
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

8128:pik3c3
gene id: 8128:pik3c3
uniprot id: A0A669DIB6
uniprot id: I3K560
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
messages: Midbody

8128:LOC100705706
gene id: 8128:LOC100705706
uniprot id: I3K3Z9
names: Similarity
messages: Belongs to the peptidase C14A family.

8128:pym1
gene id: 8128:pym1
uniprot id: A0A669BTR8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pym family.
messages: Cytoplasm
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

8128:porcn
gene id: 8128:porcn
uniprot id: A0A669BAE0
names: Subcellular Location Annotation
messages: Membrane

8128:arl2bp
gene id: 8128:arl2bp
uniprot id: I3JVH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.
messages: centrosome
messages: cilium basal body

8128:LOC100707375
gene id: 8128:LOC100707375
uniprot id: I3J1W9
names: Similarity
messages: Belongs to the MS4A family.

8128:vasp
gene id: 8128:vasp
uniprot id: A0A669ECZ1
uniprot id: I3JD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

8128:LOC100700877
gene id: 8128:LOC100700877
uniprot id: I3JBB9
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

8128:egr1
gene id: 8128:egr1
uniprot id: A0A669E2V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

8128:lyrm7
gene id: 8128:lyrm7
uniprot id: A0A669CFI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.
messages: Belongs to the complex I LYR family.
messages: Interacts with UQCRFS1.
messages: Mitochondrion matrix

8128:ndufa10
gene id: 8128:ndufa10
uniprot id: I3JVH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.
messages: Mitochondrion matrix

8128:nell2
gene id: 8128:nell2
uniprot id: I3JQ54
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100702315
gene id: 8128:LOC100702315
uniprot id: I3KVN9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100706941
gene id: 8128:LOC100706941
uniprot id: I3KHJ4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100698998
gene id: 8128:LOC100698998
uniprot id: I3JYT9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100710305
gene id: 8128:LOC100710305
uniprot id: A0A669E8U6
names: Similarity
messages: Belongs to the BZW family.

8128:nrp1
gene id: 8128:nrp1
uniprot id: I3J6Z0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:ldlrad2
gene id: 8128:ldlrad2
uniprot id: I3JAF2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100692650
gene id: 8128:LOC100692650
uniprot id: A0A669BMQ8
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

8128:slc16a4
gene id: 8128:slc16a4
uniprot id: I3J2T1
names: Subcellular Location Annotation
messages: Membrane

8128:ndufb11
gene id: 8128:ndufb11
uniprot id: A0A669EHF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane

8128:letmd1
gene id: 8128:letmd1
uniprot id: I3KIW6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100707316
gene id: 8128:LOC100707316
uniprot id: A0A669B683
uniprot id: A0A669BVP3
names: Similarity
messages: Belongs to the peptidase M10A family.

8128:cep70
gene id: 8128:cep70
uniprot id: A0A669CC70
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

8128:atp1b4
gene id: 8128:atp1b4
uniprot id: I3J2V5
uniprot id: I3J2V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8128:LOC100712014
gene id: 8128:LOC100712014
uniprot id: I3JCD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

8128:ube3d
gene id: 8128:ube3d
uniprot id: I3ITZ6
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

8128:atp6v0b
gene id: 8128:atp6v0b
uniprot id: A0A669EDN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

8128:fitm2
gene id: 8128:fitm2
uniprot id: I3KI53
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100696990
gene id: 8128:LOC100696990
uniprot id: A0A669E628
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC106098495
gene id: 8128:LOC106098495
uniprot id: I3IYA1
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

8128:LOC100694813
gene id: 8128:LOC100694813
uniprot id: I3KJY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8128:LOC102080448
gene id: 8128:LOC102080448
uniprot id: A0A669EU93
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100701289
gene id: 8128:LOC100701289
uniprot id: A0A669DZB9
uniprot id: I3KP58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

8128:lztfl1
gene id: 8128:lztfl1
uniprot id: I3JGE4
uniprot id: I3JGE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

8128:LOC100699645
gene id: 8128:LOC100699645
uniprot id: A0A669CS47
uniprot id: A0A669DCQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein phosphatase inhibitor 1 family.
messages: Cytoplasm
messages: Inhibitor of protein-phosphatase 1.

8128:LOC100694127
gene id: 8128:LOC100694127
uniprot id: A0A669EKB9
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

8128:lg5h6orf89
gene id: 8128:lg5h6orf89
uniprot id: I3IVM6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

8128:tmed2
gene id: 8128:tmed2
uniprot id: A0A669CKU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

8128:LOC100699829
gene id: 8128:LOC100699829
uniprot id: A0A669BVB3
names: Subcellular Location Annotation
messages: Membrane

8128:clstn3
gene id: 8128:clstn3
uniprot id: A0A669BF10
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

8128:slc50a1
gene id: 8128:slc50a1
uniprot id: I3JGG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Membrane

8128:LOC100704500
gene id: 8128:LOC100704500
uniprot id: I3JBQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

8128:maf1
gene id: 8128:maf1
uniprot id: I3JFF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

8128:melk
gene id: 8128:melk
uniprot id: A0A669DVI0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

8128:LOC100693121
gene id: 8128:LOC100693121
uniprot id: I3JW79
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8128:LOC100696012
gene id: 8128:LOC100696012
uniprot id: I3K371
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC100708080
gene id: 8128:LOC100708080
uniprot id: A0A669BMP7
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

8128:lg22h1orf43
gene id: 8128:lg22h1orf43
uniprot id: I3KUQ1
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

8128:acaa2
gene id: 8128:acaa2
uniprot id: A0A669CUR8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8128:LOC100698977
gene id: 8128:LOC100698977
uniprot id: I3K4L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cell membrane
messages: Interacts with SLC4A4.
messages: Membrane
messages: Reversible hydration of carbon dioxide.

8128:LOC102077011
gene id: 8128:LOC102077011
uniprot id: A0A669DEQ3
names: Subcellular Location Annotation
messages: Membrane

8128:emg1
gene id: 8128:emg1
uniprot id: I3K529
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

8128:LOC100700562
gene id: 8128:LOC100700562
uniprot id: I3K7I4
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:fmnl3
gene id: 8128:fmnl3
uniprot id: I3K2J1
names: Similarity
messages: Belongs to the formin homology family.

8128:LOC100711010
gene id: 8128:LOC100711010
uniprot id: I3KBF2
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

8128:panx3
gene id: 8128:panx3
uniprot id: I3KFG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8128:mrpl18
gene id: 8128:mrpl18
uniprot id: I3JBB4
names: Similarity
messages: Belongs to the universal ribosomal protein uL18 family.

8128:LOC100696048
gene id: 8128:LOC100696048
uniprot id: I3JW89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

8128:LOC100710099
gene id: 8128:LOC100710099
uniprot id: I3IUF9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8128:LOC100703904
gene id: 8128:LOC100703904
uniprot id: I3IZZ2
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

8128:LOC100694080
gene id: 8128:LOC100694080
uniprot id: I3JFI9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:atp5if1
gene id: 8128:atp5if1
uniprot id: I3KUI8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

8128:LOC100693161
gene id: 8128:LOC100693161
uniprot id: A0A669C2I0
uniprot id: A0A669EKX9
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

8128:evc2
gene id: 8128:evc2
uniprot id: A0A669EKE7
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

8128:LOC100706323
gene id: 8128:LOC100706323
uniprot id: I3KG12
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100696250
gene id: 8128:LOC100696250
uniprot id: I3IWZ1
names: Subcellular Location Annotation
messages: Membrane

8128:egfl7
gene id: 8128:egfl7
uniprot id: I3JYZ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC102076914
gene id: 8128:LOC102076914
uniprot id: A0A669D152
names: Subcellular Location Annotation
messages: Secreted

8128:LOC100701150
gene id: 8128:LOC100701150
uniprot id: I3JY49
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8128:tmem59
gene id: 8128:tmem59
uniprot id: I3KQG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:neto1
gene id: 8128:neto1
uniprot id: A0A669AZQ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC102079086
gene id: 8128:LOC102079086
uniprot id: A0A669E5B8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:vsx2
gene id: 8128:vsx2
uniprot id: I3K204
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100692310
gene id: 8128:LOC100692310
uniprot id: A0A669EYP0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:arf3
gene id: 8128:arf3
uniprot id: I3KSA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8128:kcmf1
gene id: 8128:kcmf1
uniprot id: I3JKZ8
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

8128:lamtor5
gene id: 8128:lamtor5
uniprot id: I3J2T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR5 family.
messages: Lysosome

8128:srpx
gene id: 8128:srpx
uniprot id: A0A669DWU5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100689828
gene id: 8128:LOC100689828
uniprot id: A0A669DU87
names: Similarity
messages: Belongs to the villin/gelsolin family.

8128:LOC100706477
gene id: 8128:LOC100706477
uniprot id: A0A669E418
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:LOC100712078
gene id: 8128:LOC100712078
uniprot id: I3K493
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100708062
gene id: 8128:LOC100708062
uniprot id: I3KMJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:LOC100693558
gene id: 8128:LOC100693558
uniprot id: A0A669BPC1
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

8128:LOC100711618
gene id: 8128:LOC100711618
uniprot id: I3K977
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8128:LOC109202555
gene id: 8128:LOC109202555
uniprot id: A0A669C0D8
names: Similarity
messages: Belongs to the VPS28 family.

8128:slc45a3
gene id: 8128:slc45a3
uniprot id: I3JVM9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC109194146
gene id: 8128:LOC109194146
uniprot id: A0A669BSG1
names: Similarity
messages: Belongs to the TCF/LEF family.

8128:tubgcp6
gene id: 8128:tubgcp6
uniprot id: A0A669EII3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: centrosome

8128:ptk2b
gene id: 8128:ptk2b
uniprot id: I3KDQ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

8128:LOC100703282
gene id: 8128:LOC100703282
uniprot id: A0A669DDQ6
names: Similarity
messages: Belongs to the CDI family.

8128:ddx55
gene id: 8128:ddx55
uniprot id: A0A669C5I8
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:nup62
gene id: 8128:nup62
uniprot id: I3JQ02
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

8128:LOC100701390
gene id: 8128:LOC100701390
uniprot id: I3K6L1
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

8128:lnpk
gene id: 8128:lnpk
uniprot id: A0A669CEJ4
uniprot id: A0A669EZL9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

8128:LOC100702592
gene id: 8128:LOC100702592
uniprot id: I3KVH9
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100705868
gene id: 8128:LOC100705868
uniprot id: I3J8E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8128:LOC100702337
gene id: 8128:LOC100702337
uniprot id: I3KCN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

8128:bud13
gene id: 8128:bud13
uniprot id: I3JBD8
names: Similarity
messages: Belongs to the CWC26 family.

8128:LOC100709849
gene id: 8128:LOC100709849
uniprot id: I3JYC1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:ncbp1
gene id: 8128:ncbp1
uniprot id: I3IZ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

8128:ndufb8
gene id: 8128:ndufb8
uniprot id: I3KGK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8128:LOC100704852
gene id: 8128:LOC100704852
uniprot id: I3KYW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:med9
gene id: 8128:med9
uniprot id: A0A669CU53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8128:iqsec3
gene id: 8128:iqsec3
uniprot id: A0A669D6Z7
names: Similarity
messages: Belongs to the BRAG family.

8128:ansn
gene id: 8128:ansn
uniprot id: Q3LHN4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

8128:dgke
gene id: 8128:dgke
uniprot id: A0A669DRP7
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8128:KEH09 p05
gene id: 8128:KEH09_p05
uniprot id: D2KP32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

8128:tagln3
gene id: 8128:tagln3
uniprot id: I3K9L9
names: Similarity
messages: Belongs to the calponin family.

8128:LOC100696783
gene id: 8128:LOC100696783
uniprot id: I3K1F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

8128:sf3a3
gene id: 8128:sf3a3
uniprot id: I3JVQ3
names: Similarity
messages: Belongs to the SF3A3 family.

8128:LOC100707119
gene id: 8128:LOC100707119
uniprot id: I3KNE8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100690683
gene id: 8128:LOC100690683
uniprot id: I3KJE6
names: Subcellular Location Annotation
messages: Mitochondrion

8128:LOC100695797
gene id: 8128:LOC100695797
uniprot id: A0A669BMS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100696112
gene id: 8128:LOC100696112
uniprot id: A0A669BB95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8128:LOC100707599
gene id: 8128:LOC100707599
uniprot id: A0A669EC89
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:kcnd1
gene id: 8128:kcnd1
uniprot id: I3KBD9
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

8128:LOC100699203
gene id: 8128:LOC100699203
uniprot id: A0A669EIS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

8128:ebf2
gene id: 8128:ebf2
uniprot id: A0A669AXZ5
uniprot id: I3K6N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

8128:mospd1
gene id: 8128:mospd1
uniprot id: I3KM32
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC102080248
gene id: 8128:LOC102080248
uniprot id: A0A669F677
names: Subcellular Location Annotation
messages: Membrane

8128:clic4
gene id: 8128:clic4
uniprot id: I3JN89
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8128:LOC100708033
gene id: 8128:LOC100708033
uniprot id: I3JBT2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100711843
gene id: 8128:LOC100711843
uniprot id: I3K2W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

8128:fggy
gene id: 8128:fggy
uniprot id: A0A669DQ61
names: Similarity
messages: Belongs to the FGGY kinase family.

8128:LOC100700713
gene id: 8128:LOC100700713
uniprot id: A0A669C956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cytoplasm
messages: Postsynaptic density

8128:LOC100692909
gene id: 8128:LOC100692909
uniprot id: A0A669CJT8
uniprot id: A0A669F1X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

8128:rrp7a
gene id: 8128:rrp7a
uniprot id: I3JNS3
names: Similarity
messages: Belongs to the RRP7 family.

8128:LOC100705673
gene id: 8128:LOC100705673
uniprot id: I3JLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8128:LOC100696824
gene id: 8128:LOC100696824
uniprot id: A0A669CR11
names: Subcellular Location Annotation
messages: Membrane

8128:gdf9
gene id: 8128:gdf9
uniprot id: I3K542
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

8128:LOC100693580
gene id: 8128:LOC100693580
uniprot id: I3IVX6
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100709286
gene id: 8128:LOC100709286
uniprot id: I3JIR0
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:neurod2
gene id: 8128:neurod2
uniprot id: I3KYN7
names: Subcellular Location Annotation
messages: Nucleus

8128:st8sia5
gene id: 8128:st8sia5
uniprot id: A0A669BQL2
uniprot id: A0A669D190
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC100702753
gene id: 8128:LOC100702753
uniprot id: A0A669BMP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100700755
gene id: 8128:LOC100700755
uniprot id: A0A669CUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

8128:ptar1
gene id: 8128:ptar1
uniprot id: I3K8Q9
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

8128:LOC100705521
gene id: 8128:LOC100705521
uniprot id: I3K0X0
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8128:gabra4
gene id: 8128:gabra4
uniprot id: I3KFH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100690390
gene id: 8128:LOC100690390
uniprot id: I3JHB0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100709801
gene id: 8128:LOC100709801
uniprot id: I3JB58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:lingo3
gene id: 8128:lingo3
uniprot id: I3KZW3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100704236
gene id: 8128:LOC100704236
uniprot id: I3JE52
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:aste1
gene id: 8128:aste1
uniprot id: I3J106
names: Similarity
messages: Belongs to the asteroid family.

8128:LOC100702412
gene id: 8128:LOC100702412
uniprot id: I3JT46
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

8128:KEH09 p04
gene id: 8128:KEH09_p04
uniprot id: D2KP33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

8128:itgb1
gene id: 8128:itgb1
uniprot id: A0A669BIJ9
uniprot id: A0A669EIH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

8128:LOC102078900
gene id: 8128:LOC102078900
uniprot id: I3K255
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100690134
gene id: 8128:LOC100690134
uniprot id: I3KZ76
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:kti12
gene id: 8128:kti12
uniprot id: I3KDG6
names: Similarity
messages: Belongs to the KTI12 family.

8128:LOC100710995
gene id: 8128:LOC100710995
uniprot id: I3KIX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

8128:LOC100705065
gene id: 8128:LOC100705065
uniprot id: I3JB75
names: Similarity
messages: Belongs to the splicing factor SR family.

8128:itga7
gene id: 8128:itga7
uniprot id: A0A669CLD2
uniprot id: A0A669CZW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:LOC100704632
gene id: 8128:LOC100704632
uniprot id: A0A669BI26
names: Similarity
messages: Belongs to the THADA family.

8128:LOC100710321
gene id: 8128:LOC100710321
uniprot id: I3JR54
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:rflnb
gene id: 8128:rflnb
uniprot id: A0A669AY68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

8128:LOC100703378
gene id: 8128:LOC100703378
uniprot id: I3JHD8
names: Similarity
messages: Belongs to the FAM131 family.

8128:gpm6b
gene id: 8128:gpm6b
uniprot id: I3KGF7
uniprot id: I3KGF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8128:LOC100703682
gene id: 8128:LOC100703682
uniprot id: I3JXR6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100704022
gene id: 8128:LOC100704022
uniprot id: A0A669BG79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

8128:tcp11l1
gene id: 8128:tcp11l1
uniprot id: I3JYE5
names: Similarity
messages: Belongs to the TCP11 family.

8128:LOC100691871
gene id: 8128:LOC100691871
uniprot id: A0A669DNK6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

8128:prpf19
gene id: 8128:prpf19
uniprot id: I3JB97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

8128:LOC100695379
gene id: 8128:LOC100695379
uniprot id: A0A669DU98
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100701817
gene id: 8128:LOC100701817
uniprot id: I3J6F2
names: Similarity
messages: Belongs to the PP2C family.

8128:zdhhc12
gene id: 8128:zdhhc12
uniprot id: A0A669F6T0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC100694046
gene id: 8128:LOC100694046
uniprot id: I3JNQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:sec24b
gene id: 8128:sec24b
uniprot id: A0A669CEL5
uniprot id: A0A669D4V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8128:hs3st5
gene id: 8128:hs3st5
uniprot id: I3JZI9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:rnd3
gene id: 8128:rnd3
uniprot id: A0A669B225
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

8128:LOC100694055
gene id: 8128:LOC100694055
uniprot id: I3JXU1
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

8128:LOC100707713
gene id: 8128:LOC100707713
uniprot id: I3K879
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

8128:LOC100691037
gene id: 8128:LOC100691037
uniprot id: I3K9F4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690483
gene id: 8128:LOC100690483
uniprot id: A0A669DFK6
uniprot id: I3J1I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

8128:reep5
gene id: 8128:reep5
uniprot id: A0A669DZY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

8128:tmem39b
gene id: 8128:tmem39b
uniprot id: I3K2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

8128:hdac3
gene id: 8128:hdac3
uniprot id: A0A669C051
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

8128:agrp2
gene id: 8128:agrp2
uniprot id: J3JQY1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:mrps25
gene id: 8128:mrps25
uniprot id: I3KKU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

8128:LOC100704625
gene id: 8128:LOC100704625
uniprot id: A0A669EXL8
uniprot id: I3JHP3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:kdm1b
gene id: 8128:kdm1b
uniprot id: I3K8G8
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8128:hscb
gene id: 8128:hscb
uniprot id: I3JWY0
names: Similarity
messages: Belongs to the HscB family.

8128:LOC100710737
gene id: 8128:LOC100710737
uniprot id: I3J028
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

8128:ppp2r5b
gene id: 8128:ppp2r5b
uniprot id: A0A669ECH1
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8128:LOC100690385
gene id: 8128:LOC100690385
uniprot id: I3KNP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:edil3
gene id: 8128:edil3
uniprot id: A0A669DKA2
uniprot id: A0A669ESL5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:celf4
gene id: 8128:celf4
uniprot id: A0A669B749
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

8128:rps11
gene id: 8128:rps11
uniprot id: A0A669EN20
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

8128:LOC100692510
gene id: 8128:LOC100692510
uniprot id: I3J2G4
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100699698
gene id: 8128:LOC100699698
uniprot id: A0A669C8A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:adamts5
gene id: 8128:adamts5
uniprot id: I3K2F6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:slc25a36
gene id: 8128:slc25a36
uniprot id: I3KBA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:kif1bp
gene id: 8128:kif1bp
uniprot id: I3JDF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

8128:skor2
gene id: 8128:skor2
uniprot id: I3J8J1
names: Similarity
messages: Belongs to the SKI family.

8128:LOC100702079
gene id: 8128:LOC100702079
uniprot id: I3JE66
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8128:LOC100697436
gene id: 8128:LOC100697436
uniprot id: I3J011
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100702924
gene id: 8128:LOC100702924
uniprot id: A0A669BZQ2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100708325
gene id: 8128:LOC100708325
uniprot id: I3KB72
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

8128:LOC100699981
gene id: 8128:LOC100699981
uniprot id: A0A669CHK7
uniprot id: I3KVU6
uniprot id: I3KVU7
names: Subcellular Location Annotation
messages: Membrane

8128:fut7
gene id: 8128:fut7
uniprot id: I3KX61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8128:LOC100703329
gene id: 8128:LOC100703329
uniprot id: I3JMN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

8128:upf3a
gene id: 8128:upf3a
uniprot id: I3JIA9
names: Similarity
messages: Belongs to the RENT3 family.

8128:LOC100707558
gene id: 8128:LOC100707558
uniprot id: I3JFH5
names: Similarity
messages: Belongs to the FXYD family.

8128:dusp7
gene id: 8128:dusp7
uniprot id: A0A669DBC5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8128:LOC100696033
gene id: 8128:LOC100696033
uniprot id: I3K7T3
names: Similarity
messages: Belongs to the TTC39 family.

8128:LOC100690194
gene id: 8128:LOC100690194
uniprot id: A0A669BPD2
names: Similarity
messages: Belongs to the TMEM178 family.

8128:LOC100708045
gene id: 8128:LOC100708045
uniprot id: A0A669EWF9
names: Similarity
messages: Belongs to the LSM14 family.

8128:LOC102076967
gene id: 8128:LOC102076967
uniprot id: I3KG59
names: Similarity
messages: Belongs to the arrestin family.

8128:extl3
gene id: 8128:extl3
uniprot id: I3JEX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8128:rif1
gene id: 8128:rif1
uniprot id: A0A669B4W5
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

8128:rab4a
gene id: 8128:rab4a
uniprot id: I3KK77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

8128:LOC100692610
gene id: 8128:LOC100692610
uniprot id: I3IYI5
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

8128:LOC100695809
gene id: 8128:LOC100695809
uniprot id: I3JV03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

8128:coro2b
gene id: 8128:coro2b
uniprot id: I3JE35
names: Similarity
messages: Belongs to the WD repeat coronin family.

8128:grpel1
gene id: 8128:grpel1
uniprot id: A0A669DFC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

8128:gpn3
gene id: 8128:gpn3
uniprot id: I3J7B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

8128:lsm5
gene id: 8128:lsm5
uniprot id: A0A669F4J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

8128:usp45
gene id: 8128:usp45
uniprot id: A0A669CSA7
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:LOC100699163
gene id: 8128:LOC100699163
uniprot id: I3K6I5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100697979
gene id: 8128:LOC100697979
uniprot id: I3JWF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8128:LOC102075906
gene id: 8128:LOC102075906
uniprot id: I3KM18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

8128:LOC100712567
gene id: 8128:LOC100712567
uniprot id: I3J1E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8128:lamtor1
gene id: 8128:lamtor1
uniprot id: I3KJ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8128:LOC100691636
gene id: 8128:LOC100691636
uniprot id: I3KRC0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC100690696
gene id: 8128:LOC100690696
uniprot id: A0A669BKK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC102076799
gene id: 8128:LOC102076799
uniprot id: A0A669C8S4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:gosr1
gene id: 8128:gosr1
uniprot id: A0A669BLG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

8128:LOC100693115
gene id: 8128:LOC100693115
uniprot id: I3J7G2
names: Similarity
messages: Belongs to the AKAP95 family.

8128:LOC100705874
gene id: 8128:LOC100705874
uniprot id: I3JAT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

8128:LOC109194170
gene id: 8128:LOC109194170
uniprot id: A0A669E6Y7
uniprot id: I3IY12
uniprot id: I3JUJ9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:LOC100691517
gene id: 8128:LOC100691517
uniprot id: A0A669BDD1
uniprot id: A0A669EEA5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8128:shh
gene id: 8128:shh
uniprot id: I3JF43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

8128:LOC100698787
gene id: 8128:LOC100698787
uniprot id: I3J3J7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:eri1
gene id: 8128:eri1
uniprot id: I3KN10
names: Subcellular Location Annotation
messages: Cytoplasm

8128:cpne8
gene id: 8128:cpne8
uniprot id: I3JU05
names: Similarity
messages: Belongs to the copine family.

8128:cryaa
gene id: 8128:cryaa
uniprot id: I3J788
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm

8128:LOC100702291
gene id: 8128:LOC100702291
uniprot id: I3ITT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

8128:ptcd3
gene id: 8128:ptcd3
uniprot id: I3KFW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

8128:LOC100706360
gene id: 8128:LOC100706360
uniprot id: I3IWZ3
names: Similarity
messages: Belongs to the YY transcription factor family.

8128:LOC100693650
gene id: 8128:LOC100693650
uniprot id: I3J7I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

8128:fgfrl1
gene id: 8128:fgfrl1
uniprot id: I3IXH5
names: Subcellular Location Annotation
messages: Membrane

8128:gtpbp8
gene id: 8128:gtpbp8
uniprot id: I3J9U9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

8128:LOC100701309
gene id: 8128:LOC100701309
uniprot id: I3JLV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

8128:LOC100707253
gene id: 8128:LOC100707253
uniprot id: A0A669CTY5
names: Similarity
messages: Belongs to the janus family.

8128:LOC100693944
gene id: 8128:LOC100693944
uniprot id: I3K2A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

8128:LOC100690951
gene id: 8128:LOC100690951
uniprot id: I3KJF6
names: Subcellular Location Annotation
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

8128:nefm
gene id: 8128:nefm
uniprot id: I3J829
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: axon
messages: cytoskeleton

8128:LOC100704234
gene id: 8128:LOC100704234
uniprot id: A0A669CW96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

8128:kit
gene id: 8128:kit
uniprot id: A0A669EDF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:tmem107
gene id: 8128:tmem107
uniprot id: A0A669CYU0
names: Subcellular Location Annotation
messages: Membrane

8128:pex1
gene id: 8128:pex1
uniprot id: I3J1J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

8128:LOC100709185
gene id: 8128:LOC100709185
uniprot id: A0A669EZ44
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8128:LOC102079812
gene id: 8128:LOC102079812
uniprot id: A0A669C5E6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100701797
gene id: 8128:LOC100701797
uniprot id: A0A669BN38
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100709620
gene id: 8128:LOC100709620
uniprot id: I3J095
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:csnk1g1
gene id: 8128:csnk1g1
uniprot id: A0A669E1S8
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

8128:rbm5
gene id: 8128:rbm5
uniprot id: I3J8I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

8128:sigmar1
gene id: 8128:sigmar1
uniprot id: A0A669CFH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERG2 family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.
messages: Homotrimer.
messages: Membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.
messages: Vesicle

8128:cpxm2
gene id: 8128:cpxm2
uniprot id: I3KGE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

8128:LOC100696516
gene id: 8128:LOC100696516
uniprot id: A0A669E460
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8128:LOC100696595
gene id: 8128:LOC100696595
uniprot id: A0A669BH50
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:txlnb
gene id: 8128:txlnb
uniprot id: I3KR94
uniprot id: I3KR95
names: Similarity
messages: Belongs to the taxilin family.

8128:LOC100707405
gene id: 8128:LOC100707405
uniprot id: A0A669D9V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like Alba family.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
messages: nucleolus

8128:LOC100696639
gene id: 8128:LOC100696639
uniprot id: A0A669EVX4
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100709896
gene id: 8128:LOC100709896
uniprot id: I3KQ23
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

8128:st14
gene id: 8128:st14
uniprot id: I3J8E0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Degrades extracellular matrix.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100694231
gene id: 8128:LOC100694231
uniprot id: A0A669ECW2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100693219
gene id: 8128:LOC100693219
uniprot id: I3JJN1
names: Similarity
messages: Belongs to the BicD family.

8128:bmp6
gene id: 8128:bmp6
uniprot id: I3KB28
names: Similarity
messages: Belongs to the TGF-beta family.

8128:pomc
gene id: 8128:pomc
uniprot id: I3KR43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

8128:LOC100709539
gene id: 8128:LOC100709539
uniprot id: I3K6N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:LOC100689789
gene id: 8128:LOC100689789
uniprot id: I3KB86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8128:LOC100696275
gene id: 8128:LOC100696275
uniprot id: A0A669EB55
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

8128:mrpl14
gene id: 8128:mrpl14
uniprot id: A0A669CE03
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

8128:LOC100692877
gene id: 8128:LOC100692877
uniprot id: I3IWY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:LOC100698051
gene id: 8128:LOC100698051
uniprot id: I3J5X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8128:tgfb1i1
gene id: 8128:tgfb1i1
uniprot id: A0A669E5I7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
messages: Nucleus matrix
messages: The LD (leucine and aspartate-rich) motif 3 mediates interaction with GIT1 and functions as a nuclear export signal.
messages: cytoskeleton
messages: focal adhesion

8128:qtrt2
gene id: 8128:qtrt2
uniprot id: I3K995
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

8128:lhx9
gene id: 8128:lhx9
uniprot id: I3K9H4
names: Subcellular Location Annotation
messages: Nucleus

8128:lactb2
gene id: 8128:lactb2
uniprot id: I3KCD2
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

8128:mrpl37
gene id: 8128:mrpl37
uniprot id: A0A669AWU0
uniprot id: A0A669EFZ0
names: Subcellular Location Annotation
messages: Mitochondrion

8128:sf3b5
gene id: 8128:sf3b5
uniprot id: I3KY34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

8128:pdlim3
gene id: 8128:pdlim3
uniprot id: A0A669EMM3
names: Subcellular Location Annotation
messages: Z line

8128:ccnf
gene id: 8128:ccnf
uniprot id: I3JCF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: centriole
messages: perinuclear region

8128:clcn2
gene id: 8128:clcn2
uniprot id: A0A669CC89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100710242
gene id: 8128:LOC100710242
uniprot id: A0A669E973
names: Similarity
messages: Belongs to the sorting nexin family.

8128:fign
gene id: 8128:fign
uniprot id: A0A669EYT7
names: Similarity
messages: Belongs to the AAA ATPase family.

8128:LOC100707019
gene id: 8128:LOC100707019
uniprot id: I3K835
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8128:LOC100711637
gene id: 8128:LOC100711637
uniprot id: A0A669DM07
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8128:LOC100694690
gene id: 8128:LOC100694690
uniprot id: I3KD73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:ap1g1
gene id: 8128:ap1g1
uniprot id: A0A669D1T7
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8128:dtna
gene id: 8128:dtna
uniprot id: A0A669B393
uniprot id: A0A669E3T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

8128:rnf13
gene id: 8128:rnf13
uniprot id: A0A669D2L7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100701987
gene id: 8128:LOC100701987
uniprot id: A0A669DV80
names: Similarity
messages: Belongs to the globin family.

8128:mtrf1l
gene id: 8128:mtrf1l
uniprot id: I3IXQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

8128:evpl
gene id: 8128:evpl
uniprot id: I3KPF5
names: Subcellular Location Annotation
messages: cytoskeleton

8128:tacc1
gene id: 8128:tacc1
uniprot id: I3K7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

8128:LOC100700985
gene id: 8128:LOC100700985
uniprot id: I3KSD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

8128:bcas2
gene id: 8128:bcas2
uniprot id: I3JRW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

8128:LOC100705251
gene id: 8128:LOC100705251
uniprot id: A0A669F947
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693493
gene id: 8128:LOC100693493
uniprot id: I3KVG8
names: Similarity
messages: Belongs to the EPS8 family.

8128:LOC100710107
gene id: 8128:LOC100710107
uniprot id: I3JVJ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:sgtb
gene id: 8128:sgtb
uniprot id: I3JYM3
names: Similarity
messages: Belongs to the SGT family.

8128:LOC100705840
gene id: 8128:LOC100705840
uniprot id: I3KWY3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100711236
gene id: 8128:LOC100711236
uniprot id: A0A669B1V0
uniprot id: A0A669CRE3
uniprot id: A0A669DQR9
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

8128:LOC100708621
gene id: 8128:LOC100708621
uniprot id: I3JYZ4
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8128:LOC100693114
gene id: 8128:LOC100693114
uniprot id: I3K6G5
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100702093
gene id: 8128:LOC100702093
uniprot id: I3JYU7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100689790
gene id: 8128:LOC100689790
uniprot id: I3K0B4
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

8128:LOC100698681
gene id: 8128:LOC100698681
uniprot id: A0A669CA03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

8128:LOC100699999
gene id: 8128:LOC100699999
uniprot id: A0A669CWP3
uniprot id: I3KWU5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8128:LOC100695052
gene id: 8128:LOC100695052
uniprot id: A0A669EBY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100699579
gene id: 8128:LOC100699579
uniprot id: A0A669BDW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8128:rplp1
gene id: 8128:rplp1
uniprot id: I3J3T8
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

8128:LOC100690057
gene id: 8128:LOC100690057
uniprot id: A0A669AXA4
uniprot id: A0A669E426
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8128:plekho1
gene id: 8128:plekho1
uniprot id: I3IZB8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:cnksr1
gene id: 8128:cnksr1
uniprot id: I3J6C5
names: Similarity
messages: Belongs to the CNKSR family.

8128:LOC100693665
gene id: 8128:LOC100693665
uniprot id: A0A669D2J5
uniprot id: I3J5Y6
names: Similarity
messages: Belongs to the OSBP family.

8128:LOC100699837
gene id: 8128:LOC100699837
uniprot id: I3JWB9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100709775
gene id: 8128:LOC100709775
uniprot id: I3J7Y2
names: Subcellular Location Annotation
messages: P-body

8128:fgb
gene id: 8128:fgb
uniprot id: I3K9D6
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

8128:sbf2
gene id: 8128:sbf2
uniprot id: I3JFH4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8128:LOC100707716
gene id: 8128:LOC100707716
uniprot id: A0A669F4Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

8128:mrpl34
gene id: 8128:mrpl34
uniprot id: A0A669E7X8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

8128:tmem38a
gene id: 8128:tmem38a
uniprot id: I3K478
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

8128:fzd4
gene id: 8128:fzd4
uniprot id: I3JC44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

8128:LOC100698191
gene id: 8128:LOC100698191
uniprot id: A0A669C5V3
names: Subcellular Location Annotation
messages: Membrane

8128:plbd2
gene id: 8128:plbd2
uniprot id: A0A669DS06
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

8128:ndufs1
gene id: 8128:ndufs1
uniprot id: I3JPG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

8128:cdon
gene id: 8128:cdon
uniprot id: A0A669FCA6
names: Subcellular Location Annotation
messages: Membrane

8128:uxs1
gene id: 8128:uxs1
uniprot id: A0A669BP26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

8128:gsta
gene id: 8128:gsta
uniprot id: A8WE65
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

8128:LOC100696040
gene id: 8128:LOC100696040
uniprot id: I3JA28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8128:ero1a
gene id: 8128:ero1a
uniprot id: I3JJ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

8128:LOC100705846
gene id: 8128:LOC100705846
uniprot id: A0A669C5X5
names: Similarity
messages: Belongs to the CD36 family.

8128:LOC100697952
gene id: 8128:LOC100697952
uniprot id: I3JD65
names: Similarity
messages: Belongs to the sorting nexin family.

8128:LOC100695822
gene id: 8128:LOC100695822
uniprot id: I3IYT6
names: Similarity
messages: Belongs to the centrin family.

8128:oxt
gene id: 8128:oxt
uniprot id: I3KDH7
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

8128:adamts9
gene id: 8128:adamts9
uniprot id: A0A669BA95
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:pim3
gene id: 8128:pim3
uniprot id: A0A669CR41
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8128:LOC100698523
gene id: 8128:LOC100698523
uniprot id: A0A669B3I3
uniprot id: A0A669D4V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane

8128:LOC102080174
gene id: 8128:LOC102080174
uniprot id: I3KG67
names: Subcellular Location Annotation
messages: Membrane

8128:kpnb1
gene id: 8128:kpnb1
uniprot id: A0A669AZK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

8128:LOC100702877
gene id: 8128:LOC100702877
uniprot id: I3JVT6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

8128:LOC100691320
gene id: 8128:LOC100691320
uniprot id: I3IWU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

8128:exosc9
gene id: 8128:exosc9
uniprot id: I3J5Z1
names: Subcellular Location Annotation
messages: Cytoplasm

8128:itfg1
gene id: 8128:itfg1
uniprot id: I3J501
names: Similarity
messages: Belongs to the TIP family.

8128:coq7
gene id: 8128:coq7
uniprot id: A0A669EDW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

8128:phf10
gene id: 8128:phf10
uniprot id: A0A669DU81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

8128:kcng1
gene id: 8128:kcng1
uniprot id: I3KIA0
names: Subcellular Location Annotation
messages: Membrane

8128:slc35e1
gene id: 8128:slc35e1
uniprot id: A0A669E7V2
names: Subcellular Location Annotation
messages: Membrane

8128:dbnl
gene id: 8128:dbnl
uniprot id: A0A669DRJ2
uniprot id: A0A669EZ00
uniprot id: I3JWY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: Synapse
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: cytoskeleton
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

8128:kat2a
gene id: 8128:kat2a
uniprot id: I3IXQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

8128:LOC100690406
gene id: 8128:LOC100690406
uniprot id: I3KYV7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:gja10
gene id: 8128:gja10
uniprot id: I3IZH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:mboat7
gene id: 8128:mboat7
uniprot id: I3K4K3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100704637
gene id: 8128:LOC100704637
uniprot id: I3KWA9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8128:LOC100704989
gene id: 8128:LOC100704989
uniprot id: I3KQZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100703341
gene id: 8128:LOC100703341
uniprot id: A0A669CYE4
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

8128:slc44a4
gene id: 8128:slc44a4
uniprot id: I3K7A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8128:LOC100711751
gene id: 8128:LOC100711751
uniprot id: A0A669EY37
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100710985
gene id: 8128:LOC100710985
uniprot id: A0A669E7R0
uniprot id: A0A669FCC6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100697618
gene id: 8128:LOC100697618
uniprot id: I3JD99
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:LOC100703512
gene id: 8128:LOC100703512
uniprot id: A0A669DXG6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC109198956
gene id: 8128:LOC109198956
uniprot id: A0A669DWU0
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8128:slc6a2
gene id: 8128:slc6a2
uniprot id: A0A669E5J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:ndufb10
gene id: 8128:ndufb10
uniprot id: I3KKS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

8128:mcm9
gene id: 8128:mcm9
uniprot id: A0A669B0I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

8128:LOC100693182
gene id: 8128:LOC100693182
uniprot id: I3J1V0
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8128:LOC100707923
gene id: 8128:LOC100707923
uniprot id: I3K6I8
names: Subcellular Location Annotation
messages: Membrane

8128:cmtr1
gene id: 8128:cmtr1
uniprot id: A0A669BBN8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

8128:LOC100711586
gene id: 8128:LOC100711586
uniprot id: A0A669BK16
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:spi1
gene id: 8128:spi1
uniprot id: I3J491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:sec16a
gene id: 8128:sec16a
uniprot id: A0A669E3S7
uniprot id: I3JKN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

8128:ddx31
gene id: 8128:ddx31
uniprot id: I3IWA7
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:fgf17
gene id: 8128:fgf17
uniprot id: I3KWJ0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:kcnk5
gene id: 8128:kcnk5
uniprot id: I3KU36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:LOC100698303
gene id: 8128:LOC100698303
uniprot id: I3JDJ1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100698414
gene id: 8128:LOC100698414
uniprot id: A0A669BXN9
uniprot id: I3KGV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

8128:cdpf1
gene id: 8128:cdpf1
uniprot id: A0A669D4F6
names: Similarity
messages: Belongs to the CDPF1 family.

8128:rassf3
gene id: 8128:rassf3
uniprot id: A0A669E1V5
names: Subcellular Location Annotation
messages: cytoskeleton

8128:LOC100709253
gene id: 8128:LOC100709253
uniprot id: I3J8L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

8128:tnip2
gene id: 8128:tnip2
uniprot id: I3JVD6
names: Subcellular Location Annotation
messages: Cytoplasm

8128:grhpr
gene id: 8128:grhpr
uniprot id: I3JQS5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

8128:LOC100695545
gene id: 8128:LOC100695545
uniprot id: A0A669CIT0
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8128:LOC100708574
gene id: 8128:LOC100708574
uniprot id: I3JBU6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100694082
gene id: 8128:LOC100694082
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:csnk2a2
gene id: 8128:csnk2a2
uniprot id: A0A669B1K1
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC109200115
gene id: 8128:LOC109200115
uniprot id: A0A669DNE3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC102079510
gene id: 8128:LOC102079510
uniprot id: I3KJB8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100704832
gene id: 8128:LOC100704832
uniprot id: I3JM16
names: Subcellular Location Annotation
messages: Membrane

8128:taf6l
gene id: 8128:taf6l
uniprot id: A0A669CRG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

8128:gdap1l1
gene id: 8128:gdap1l1
uniprot id: I3KI55
names: Similarity
messages: Belongs to the GST superfamily.

8128:yme1l1
gene id: 8128:yme1l1
uniprot id: A0A669E7Q3
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

8128:fam118b
gene id: 8128:fam118b
uniprot id: A0A669BB13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM118 family.
messages: Cajal body
messages: May play a role in Cajal bodies formation.

8128:LOC100706333
gene id: 8128:LOC100706333
uniprot id: A0A669DJ54
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100691005
gene id: 8128:LOC100691005
uniprot id: I3JC53
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

8128:LOC100709416
gene id: 8128:LOC100709416
uniprot id: I3JMY8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100690035
gene id: 8128:LOC100690035
uniprot id: I3K1Y8
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC102081907
gene id: 8128:LOC102081907
uniprot id: I3KD86
uniprot id: I3KD87
names: Subcellular Location Annotation
messages: Membrane

8128:gtf2b
gene id: 8128:gtf2b
uniprot id: I3JWS6
names: Similarity
messages: Belongs to the TFIIB family.
messages: Belongs to the cyclin family. Cyclin AB subfamily.

8128:dnpep
gene id: 8128:dnpep
uniprot id: A0A669DTT1
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

8128:LOC100700681
gene id: 8128:LOC100700681
uniprot id: A0A669EQF8
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:ppard
gene id: 8128:ppard
uniprot id: I3K1E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:LOC100703160
gene id: 8128:LOC100703160
uniprot id: I3J1Y2
names: Subcellular Location Annotation
messages: Membrane

8128:lg15h6orf58
gene id: 8128:lg15h6orf58
uniprot id: A0A669CI57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

8128:LOC100534396
gene id: 8128:LOC100534396
uniprot id: Q98SW9
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100711582
gene id: 8128:LOC100711582
uniprot id: I3KHI4
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:degs1
gene id: 8128:degs1
uniprot id: I3K5Y0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Interacts with RLBP1; the interaction increases synthesis of chromophore-precursors by DEGS1.
messages: Membrane

8128:LOC100702325
gene id: 8128:LOC100702325
uniprot id: I3KVU2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100712335
gene id: 8128:LOC100712335
uniprot id: A0A669EIY1
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8128:susd1
gene id: 8128:susd1
uniprot id: I3KFZ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100694731
gene id: 8128:LOC100694731
uniprot id: A0A669CI39
names: Subcellular Location Annotation
messages: Membrane

8128:klhl22
gene id: 8128:klhl22
uniprot id: I3JYC6
names: Subcellular Location Annotation
messages: Lysosome
messages: Nucleus
messages: centrosome
messages: cytosol
messages: spindle

8128:LOC100690943
gene id: 8128:LOC100690943
uniprot id: I3KW20
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100712032
gene id: 8128:LOC100712032
uniprot id: I3KQ63
uniprot id: I3KQ64
names: Subcellular Location Annotation
messages: Cytoplasm

8128:ccser1
gene id: 8128:ccser1
uniprot id: I3KCV3
names: Similarity
messages: Belongs to the CCSER family.

8128:tbl3
gene id: 8128:tbl3
uniprot id: I3J206
names: Subcellular Location Annotation
messages: nucleolus

8128:kdr
gene id: 8128:kdr
uniprot id: I3J4B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:mau2
gene id: 8128:mau2
uniprot id: A0A669D3C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

8128:LOC100703062
gene id: 8128:LOC100703062
uniprot id: A0A669EFZ8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

8128:LOC100712354
gene id: 8128:LOC100712354
uniprot id: A0A669CS85
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

8128:LOC100689711
gene id: 8128:LOC100689711
uniprot id: A0A669C379
names: Similarity
messages: Belongs to the MHC class I family.

8128:abt1
gene id: 8128:abt1
uniprot id: I3IWF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

8128:tufm
gene id: 8128:tufm
uniprot id: I3KTG0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8128:LOC100696649
gene id: 8128:LOC100696649
uniprot id: I3JMH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

8128:LOC100700452
gene id: 8128:LOC100700452
uniprot id: A0A669BYD6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

8128:creb3l2
gene id: 8128:creb3l2
uniprot id: I3KN34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family. ATF subfamily.
messages: Binds DNA as a dimer.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8128:LOC100701568
gene id: 8128:LOC100701568
uniprot id: I3J6Q9
names: Similarity
messages: Belongs to the copine family.

8128:bloc1s2
gene id: 8128:bloc1s2
uniprot id: A0A669AZB6
names: Similarity
messages: Belongs to the BLOC1S2 family.

8128:LOC100696561
gene id: 8128:LOC100696561
uniprot id: I3J6Z8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

8128:LOC100702173
gene id: 8128:LOC100702173
uniprot id: I3JPS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

8128:LOC100698904
gene id: 8128:LOC100698904
uniprot id: I3KXQ5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100690378
gene id: 8128:LOC100690378
uniprot id: A0A669DJN1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100700387
gene id: 8128:LOC100700387
uniprot id: I3JCQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

8128:itprip
gene id: 8128:itprip
uniprot id: I3KY31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Cell membrane
messages: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.
messages: Membrane
messages: Nucleus outer membrane

8128:nhsl2
gene id: 8128:nhsl2
uniprot id: A0A669C0N5
uniprot id: I3K1C9
uniprot id: I3K1D0
names: Similarity
messages: Belongs to the NHS family.

8128:hs2st1
gene id: 8128:hs2st1
uniprot id: I3JWT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

8128:LOC100705190
gene id: 8128:LOC100705190
uniprot id: A0A669F7Y2
names: Similarity
messages: Belongs to the ANKRD34 family.

8128:golm1
gene id: 8128:golm1
uniprot id: I3KCK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

8128:LOC100709892
gene id: 8128:LOC100709892
uniprot id: A0A669CHX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8128:rbpj
gene id: 8128:rbpj
uniprot id: A0A669EM66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

8128:LOC100706976
gene id: 8128:LOC100706976
uniprot id: A0A669DHR3
names: Similarity
messages: Belongs to the RAMP family.

8128:uros
gene id: 8128:uros
uniprot id: A0A669AYF8
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

8128:notch1
gene id: 8128:notch1
uniprot id: I3JX40
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

8128:LOC100710044
gene id: 8128:LOC100710044
uniprot id: A0A669CBN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

8128:LOC100705212
gene id: 8128:LOC100705212
uniprot id: A0A669C014
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein phosphatase inhibitor 1 family.
messages: Cytoplasm
messages: Inhibitor of protein-phosphatase 1.

8128:LOC102083298
gene id: 8128:LOC102083298
uniprot id: I3K5S1
names: Similarity
messages: Belongs to the apolipoprotein L family.

8128:atp11a
gene id: 8128:atp11a
uniprot id: I3K308
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8128:LOC100690744
gene id: 8128:LOC100690744
uniprot id: I3KYZ0
names: Similarity
messages: Belongs to the nanos family.

8128:LOC100693164
gene id: 8128:LOC100693164
uniprot id: A0A669CRP8
uniprot id: A0A669E234
uniprot id: A0A669E9X3
uniprot id: I3JCD6
names: Similarity
messages: Belongs to the MAGUK family.

8128:st6galnac5
gene id: 8128:st6galnac5
uniprot id: I3KPS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:ilkap
gene id: 8128:ilkap
uniprot id: I3IXX7
names: Similarity
messages: Belongs to the PP2C family.

8128:LOC100710068
gene id: 8128:LOC100710068
uniprot id: I3JGV9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8128:LOC100695486
gene id: 8128:LOC100695486
uniprot id: I3KXK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100700919
gene id: 8128:LOC100700919
uniprot id: I3KIK4
names: Subcellular Location Annotation
messages: Nucleus

8128:tlx3
gene id: 8128:tlx3
uniprot id: A0A669EZE1
names: Subcellular Location Annotation
messages: Nucleus

8128:epb41l5
gene id: 8128:epb41l5
uniprot id: A0A669CLS8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Photoreceptor inner segment
messages: Plays a role in the formation and organization of tight junctions during the establishment of polarity in epithelial cells.

8128:ubp1
gene id: 8128:ubp1
uniprot id: I3J208
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

8128:acat1
gene id: 8128:acat1
uniprot id: A0A669CA51
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8128:gldn
gene id: 8128:gldn
uniprot id: I3IUA7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100705883
gene id: 8128:LOC100705883
uniprot id: A0A669DHX0
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:LOC100694356
gene id: 8128:LOC100694356
uniprot id: I3K851
names: Subcellular Location Annotation
messages: Membrane

8128:ess2
gene id: 8128:ess2
uniprot id: I3K8P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

8128:nagpa
gene id: 8128:nagpa
uniprot id: I3IZ42
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:amacr
gene id: 8128:amacr
uniprot id: I3JL51
names: Similarity
messages: Belongs to the CoA-transferase III family.

8128:LOC100534529
gene id: 8128:LOC100534529
uniprot id: Q29XY8
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100695177
gene id: 8128:LOC100695177
uniprot id: A0A0E3GM92
uniprot id: A0A669C7Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8128:fam167a
gene id: 8128:fam167a
uniprot id: A0A669C8P5
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

8128:LOC100707946
gene id: 8128:LOC100707946
uniprot id: I3IZ99
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

8128:ss18l2
gene id: 8128:ss18l2
uniprot id: A0A669CM91
names: Similarity
messages: Belongs to the SS18 family.

8128:nrg4
gene id: 8128:nrg4
uniprot id: I3KDM5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:cpm
gene id: 8128:cpm
uniprot id: I3JUI8
names: Similarity
messages: Belongs to the peptidase M14 family.

8128:LOC100706717
gene id: 8128:LOC100706717
uniprot id: A0A669E7P6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100694211
gene id: 8128:LOC100694211
uniprot id: I3JZ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8128:cdk5r1
gene id: 8128:cdk5r1
uniprot id: I3KPC4
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

8128:paqr9
gene id: 8128:paqr9
uniprot id: A0A669D9Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8128:LOC109204553
gene id: 8128:LOC109204553
uniprot id: A0A669D5J1
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100690570
gene id: 8128:LOC100690570
uniprot id: I3KHL7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8128:LOC100703109
gene id: 8128:LOC100703109
uniprot id: I3KDC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:cacfd1
gene id: 8128:cacfd1
uniprot id: A0A669CZW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

8128:itm2b
gene id: 8128:itm2b
uniprot id: I3KGX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8128:nr1h3
gene id: 8128:nr1h3
uniprot id: I3JEQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8128:LOC100699603
gene id: 8128:LOC100699603
uniprot id: I3KE14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8128:LOC102076382
gene id: 8128:LOC102076382
uniprot id: A0A669DHI8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100708443
gene id: 8128:LOC100708443
uniprot id: A0A669EVR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

8128:pknox2
gene id: 8128:pknox2
uniprot id: A0A669BJ44
uniprot id: I3KFG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8128:rpl9
gene id: 8128:rpl9
uniprot id: I3JR13
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

8128:sema4g
gene id: 8128:sema4g
uniprot id: A0A669EIA3
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100709386
gene id: 8128:LOC100709386
uniprot id: I3JRW1
names: Similarity
messages: Belongs to the SNF7 family.

8128:LOC100696514
gene id: 8128:LOC100696514
uniprot id: A0A669F8J7
uniprot id: I3IWZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: lamellipodium
messages: stress fiber

8128:polg
gene id: 8128:polg
uniprot id: A0A669D6L0
names: Function
names: Subcellular Location Annotation
messages: Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
messages: mitochondrion nucleoid

8128:LOC100703490
gene id: 8128:LOC100703490
uniprot id: I3J314
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8128:LOC100695516
gene id: 8128:LOC100695516
uniprot id: A0A669DG89
names: Similarity
messages: Belongs to the TMEM121 family.

8128:LOC100706637
gene id: 8128:LOC100706637
uniprot id: I3KWZ2
names: Subcellular Location Annotation
messages: cytoskeleton

8128:rida
gene id: 8128:rida
uniprot id: I3KHW6
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.

8128:pgap1
gene id: 8128:pgap1
uniprot id: I3KJ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

8128:LOC100689728
gene id: 8128:LOC100689728
uniprot id: A0A669BTA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:stk32a
gene id: 8128:stk32a
uniprot id: I3JNX4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100700669
gene id: 8128:LOC100700669
uniprot id: A0A669AZE9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100702471
gene id: 8128:LOC100702471
uniprot id: A0A669D405
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

8128:LOC102080669
gene id: 8128:LOC102080669
uniprot id: I3KRX7
names: Similarity
messages: Belongs to the EPS8 family.

8128:pip4p2
gene id: 8128:pip4p2
uniprot id: I3J2X2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8128:lrp12
gene id: 8128:lrp12
uniprot id: A0A669EQG3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:casc4
gene id: 8128:casc4
uniprot id: I3JG65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

8128:cldn15
gene id: 8128:cldn15
uniprot id: I3JS66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:LOC109194206
gene id: 8128:LOC109194206
uniprot id: I3JPI7
names: Similarity
messages: Belongs to the peptidase C14A family.

8128:bap1
gene id: 8128:bap1
uniprot id: I3KAQ1
names: Similarity
messages: Belongs to the peptidase C12 family.

8128:nsun6
gene id: 8128:nsun6
uniprot id: I3JFG3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

8128:cacnb2
gene id: 8128:cacnb2
uniprot id: A0A669BN02
uniprot id: A0A669C4P3
uniprot id: A0A669DIL3
uniprot id: I3JFG5
names: Function
names: Similarity
messages: Belongs to the calcium channel beta subunit family.
messages: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.

8128:LOC106098690
gene id: 8128:LOC106098690
uniprot id: A0A669CQY1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693228
gene id: 8128:LOC100693228
uniprot id: I3K298
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: Membrane

8128:atm
gene id: 8128:atm
uniprot id: I3JDG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Nucleus

8128:LOC100698131
gene id: 8128:LOC100698131
uniprot id: A0A669BDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8128:nupr1
gene id: 8128:nupr1
uniprot id: A0A669C5N5
names: Similarity
messages: Belongs to the NUPR family.

8128:LOC100705722
gene id: 8128:LOC100705722
uniprot id: A0A669C2X9
names: Similarity
messages: Belongs to the DNA photolyase class-2 family.

8128:LOC100705593
gene id: 8128:LOC100705593
uniprot id: A0A669D0N2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8128:fam131a
gene id: 8128:fam131a
uniprot id: I3JXI1
names: Similarity
messages: Belongs to the FAM131 family.

8128:kdelr3
gene id: 8128:kdelr3
uniprot id: A0A669B962
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100705800
gene id: 8128:LOC100705800
uniprot id: I3J8R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8128:nab1
gene id: 8128:nab1
uniprot id: I3K2N3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

8128:LOC100709321
gene id: 8128:LOC100709321
uniprot id: I3JCS1
uniprot id: I3JCS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:agbl5
gene id: 8128:agbl5
uniprot id: A0A669C8I9
uniprot id: I3IXK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Midbody
messages: Nucleus
messages: cytosol
messages: spindle

8128:mpv17l2
gene id: 8128:mpv17l2
uniprot id: I3K4G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

8128:suz12
gene id: 8128:suz12
uniprot id: I3KNV3
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

8128:mars
gene id: 8128:mars
uniprot id: A0A669B1E8
uniprot id: A0A669DSP3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8128:LOC102075730
gene id: 8128:LOC102075730
uniprot id: A0A669CCU7
names: Similarity
messages: Belongs to the arrestin family.

8128:LOC100701809
gene id: 8128:LOC100701809
uniprot id: A0A669BJ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

8128:smarcd2
gene id: 8128:smarcd2
uniprot id: I3KHZ3
names: Similarity
messages: Belongs to the SMARCD family.

8128:mep1b
gene id: 8128:mep1b
uniprot id: A0A669BNM7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:ociad1
gene id: 8128:ociad1
uniprot id: I3KNH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OCIAD1 family.
messages: Endosome
messages: Interacts with STAT3.
messages: Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.
messages: The OCIA domain is necessary and sufficient for endosomal localization.

8128:gpr119
gene id: 8128:gpr119
uniprot id: I3K6B0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:eomes
gene id: 8128:eomes
uniprot id: A0A669B177
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:LOC100706653
gene id: 8128:LOC100706653
uniprot id: I3KZW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

8128:LOC100694595
gene id: 8128:LOC100694595
uniprot id: A0A669ETY9
uniprot id: I3JXX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8128:LOC100696249
gene id: 8128:LOC100696249
uniprot id: I3KEC5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100693660
gene id: 8128:LOC100693660
uniprot id: A0A669EG53
names: Similarity
messages: Belongs to the pyridoxine kinase family.

8128:LOC100694009
gene id: 8128:LOC100694009
uniprot id: I3KC54
names: Subcellular Location Annotation
messages: Nucleus

8128:bbs2
gene id: 8128:bbs2
uniprot id: A0A669CDQ9
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

8128:LOC100711322
gene id: 8128:LOC100711322
uniprot id: A0A669B9D7
names: Similarity
messages: Belongs to the myozenin family.

8128:LOC100693510
gene id: 8128:LOC100693510
uniprot id: I3IY13
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100704373
gene id: 8128:LOC100704373
uniprot id: I3KZE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

8128:LOC100706438
gene id: 8128:LOC100706438
uniprot id: A0A669CII0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:setdb1
gene id: 8128:setdb1
uniprot id: I3JGZ5
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8128:acer3
gene id: 8128:acer3
uniprot id: A0A669D1I5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100709854
gene id: 8128:LOC100709854
uniprot id: I3K5U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8128:mrps5
gene id: 8128:mrps5
uniprot id: I3IXW6
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

8128:dll1
gene id: 8128:dll1
uniprot id: I3KK57
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8128:LOC109203025
gene id: 8128:LOC109203025
uniprot id: A0A669DFM2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100705914
gene id: 8128:LOC100705914
uniprot id: I3KK84
names: Similarity
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.

8128:psmd12
gene id: 8128:psmd12
uniprot id: I3JH38
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

8128:LOC100691082
gene id: 8128:LOC100691082
uniprot id: A0A669EBM3
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8128:coq5
gene id: 8128:coq5
uniprot id: I3JWK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

8128:LOC100701785
gene id: 8128:LOC100701785
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:LOC100694996
gene id: 8128:LOC100694996
uniprot id: I3KJ25
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

8128:nr0b2
gene id: 8128:nr0b2
uniprot id: Q8AUM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

8128:LOC100711069
gene id: 8128:LOC100711069
uniprot id: I3KE47
names: Similarity
messages: Belongs to the spectrin family.

8128:hadh
gene id: 8128:hadh
uniprot id: I3KLS8
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

8128:cct4
gene id: 8128:cct4
uniprot id: I3ITU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8128:xk
gene id: 8128:xk
uniprot id: A0A669DQF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:tbce
gene id: 8128:tbce
uniprot id: A0A669DCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

8128:LOC106097004
gene id: 8128:LOC106097004
uniprot id: I3J379
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100711003
gene id: 8128:LOC100711003
uniprot id: A0A669DH35
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:zdhhc9
gene id: 8128:zdhhc9
uniprot id: A0A669BZS8
uniprot id: A0A669C0M2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:nasp
gene id: 8128:nasp
uniprot id: A0A669DAI9
uniprot id: I3JQT2
uniprot id: I3JQT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

8128:LOC100703600
gene id: 8128:LOC100703600
uniprot id: I3JRS4
names: Subcellular Location Annotation
messages: cytoskeleton

8128:miga1
gene id: 8128:miga1
uniprot id: I3KPU0
names: Similarity
messages: Belongs to the mitoguardin family.

8128:LOC102079319
gene id: 8128:LOC102079319
uniprot id: A0A669BFB5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100694013
gene id: 8128:LOC100694013
uniprot id: I3J5T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

8128:ace2
gene id: 8128:ace2
uniprot id: A0A669DS63
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

8128:LOC100710257
gene id: 8128:LOC100710257
uniprot id: A0A669BWN0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

8128:LOC100698413
gene id: 8128:LOC100698413
uniprot id: I3KSG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNTX/VTX toxin family.
messages: Secreted

8128:LOC100698009
gene id: 8128:LOC100698009
uniprot id: I3IVD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

8128:LOC102080384
gene id: 8128:LOC102080384
uniprot id: A0A669C8S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

8128:LOC100698945
gene id: 8128:LOC100698945
uniprot id: I3KNR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

8128:LOC100710608
gene id: 8128:LOC100710608
uniprot id: I3KBZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:ndufa7
gene id: 8128:ndufa7
uniprot id: A0A669C8Z9
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA7 subunit family.
messages: Complex I is composed of 45 different subunits.

8128:LOC100711090
gene id: 8128:LOC100711090
uniprot id: I3J283
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100691436
gene id: 8128:LOC100691436
uniprot id: A0A669FBD9
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100710255
gene id: 8128:LOC100710255
uniprot id: A0A669EIW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

8128:prkra
gene id: 8128:prkra
uniprot id: I3JPJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRKRA family.
messages: perinuclear region

8128:LOC100705618
gene id: 8128:LOC100705618
uniprot id: A0A669DYL2
uniprot id: A0A669ESU2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC102080590
gene id: 8128:LOC102080590
uniprot id: A0A669DL43
names: Similarity
messages: Belongs to the MS4A family.

8128:LOC100700472
gene id: 8128:LOC100700472
uniprot id: I3KQX7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

8128:polr3b
gene id: 8128:polr3b
uniprot id: A0A669DSK9
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

8128:LOC100691693
gene id: 8128:LOC100691693
uniprot id: A0A669BJV1
names: Similarity
messages: Belongs to the peptidase M10A family.

8128:mpped1
gene id: 8128:mpped1
uniprot id: A0A669E4A6
names: Similarity
messages: Belongs to the UPF0046 family.

8128:sgsm3
gene id: 8128:sgsm3
uniprot id: I3J148
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

8128:LOC100691116
gene id: 8128:LOC100691116
uniprot id: A0A669BDX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100692215
gene id: 8128:LOC100692215
uniprot id: A0A669BF99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

8128:ncbp3
gene id: 8128:ncbp3
uniprot id: I3JKH5
names: Similarity
messages: Belongs to the NCBP3 family.

8128:entr1
gene id: 8128:entr1
uniprot id: A0A669EBL0
names: Similarity
messages: Belongs to the ENTR1 family.

8128:bfsp1
gene id: 8128:bfsp1
uniprot id: I3IV03
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cell cortex
messages: cytoskeleton

8128:LOC100695571
gene id: 8128:LOC100695571
uniprot id: A0A669DV03
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8128:LOC100703436
gene id: 8128:LOC100703436
uniprot id: A0A669E8F3
uniprot id: I3KDE0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

8128:LOC106096557
gene id: 8128:LOC106096557
uniprot id: A0A669CH32
names: Subcellular Location Annotation
messages: Nucleus

8128:eef1b2
gene id: 8128:eef1b2
uniprot id: I3KM89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

8128:dcaf10
gene id: 8128:dcaf10
uniprot id: I3IVB3
names: Function
names: Similarity
messages: Belongs to the WD repeat DCAF10 family.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

8128:cdh24
gene id: 8128:cdh24
uniprot id: I3KEI5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8128:sarm1
gene id: 8128:sarm1
uniprot id: A0A669C528
names: Similarity
messages: Belongs to the SARM1 family.

8128:LOC100534553
gene id: 8128:LOC100534553
uniprot id: A0A669EW19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC100690528
gene id: 8128:LOC100690528
uniprot id: I3KYW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:limk2
gene id: 8128:limk2
uniprot id: A0A669EYX2
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

8128:LOC100696095
gene id: 8128:LOC100696095
uniprot id: A0A669BEN7
names: Similarity
messages: Belongs to the FRAS1 family.

8128:LOC100689731
gene id: 8128:LOC100689731
uniprot id: A0A669BHI1
uniprot id: I3KT55
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

8128:nsa2
gene id: 8128:nsa2
uniprot id: A0A669B0F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

8128:LOC100705534
gene id: 8128:LOC100705534
uniprot id: A0A669BV28
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:fam135b
gene id: 8128:fam135b
uniprot id: I3JL96
names: Similarity
messages: Belongs to the FAM135 family.

8128:LOC100696844
gene id: 8128:LOC100696844
uniprot id: I3JWJ4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:jmjd1c
gene id: 8128:jmjd1c
uniprot id: A0A669E5C4
uniprot id: I3JJS9
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100702360
gene id: 8128:LOC100702360
uniprot id: I3JB06
names: Similarity
messages: Belongs to the multicopper oxidase family.

8128:LOC100705007
gene id: 8128:LOC100705007
uniprot id: I3IWQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8128:p2ry4
gene id: 8128:p2ry4
uniprot id: I3KXQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100709713
gene id: 8128:LOC100709713
uniprot id: A0A669BFM9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100704714
gene id: 8128:LOC100704714
uniprot id: A0A669B112
uniprot id: A0A669E8Q1
uniprot id: A0A669EER2
uniprot id: A0A669EYD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

8128:kmt5a
gene id: 8128:kmt5a
uniprot id: A0A669BLE4
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8128:LOC100710349
gene id: 8128:LOC100710349
uniprot id: I3JGB6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8128:mrps10
gene id: 8128:mrps10
uniprot id: A0A669DA60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

8128:LOC100708132
gene id: 8128:LOC100708132
uniprot id: A0A669D8D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

8128:LOC100710671
gene id: 8128:LOC100710671
uniprot id: I3K4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:cmtm8
gene id: 8128:cmtm8
uniprot id: A0A669C6I9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100704766
gene id: 8128:LOC100704766
uniprot id: I3K1S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:actr6
gene id: 8128:actr6
uniprot id: A0A669BXS1
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.

8128:slc33a1
gene id: 8128:slc33a1
uniprot id: I3JDJ3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100708012
gene id: 8128:LOC100708012
uniprot id: A0A669BW10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

8128:LOC100703583
gene id: 8128:LOC100703583
uniprot id: A0A669CBB8
uniprot id: I3JWL7
names: Similarity
messages: Belongs to the uridine kinase family.

8128:tead1
gene id: 8128:tead1
uniprot id: A0A669BW43
uniprot id: A0A669DZ52
uniprot id: I3JFA5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100711327
gene id: 8128:LOC100711327
uniprot id: A0A669ER40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. FIT1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol.
messages: Membrane

8128:LOC100697719
gene id: 8128:LOC100697719
uniprot id: A0A669ERD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:tacr3b
gene id: 8128:tacr3b
uniprot id: A0A075QUD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:lhx2
gene id: 8128:lhx2
uniprot id: A0A669BLA9
names: Subcellular Location Annotation
messages: Nucleus

8128:gtpbp3
gene id: 8128:gtpbp3
uniprot id: I3JV23
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

8128:ndufaf1
gene id: 8128:ndufaf1
uniprot id: I3KU85
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

8128:LOC100702441
gene id: 8128:LOC100702441
uniprot id: A0A669B2I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:LOC100693567
gene id: 8128:LOC100693567
uniprot id: A0A669BCK5
names: Subcellular Location Annotation
messages: Nucleus

8128:mknk2
gene id: 8128:mknk2
uniprot id: I3JUY9
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100709650
gene id: 8128:LOC100709650
uniprot id: A0A669D0M3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Secreted

8128:LOC100711773
gene id: 8128:LOC100711773
uniprot id: I3JY55
names: Similarity
messages: Belongs to the BRINP family.

8128:ltn1
gene id: 8128:ltn1
uniprot id: I3JAZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

8128:map1lc3c
gene id: 8128:map1lc3c
uniprot id: I3JI36
names: Similarity
messages: Belongs to the ATG8 family.

8128:LOC100701325
gene id: 8128:LOC100701325
uniprot id: I3IUN2
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

8128:LOC100708728
gene id: 8128:LOC100708728
uniprot id: A0A669BED9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:thrb
gene id: 8128:thrb
uniprot id: A0A669CGQ3
uniprot id: S5SY58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8128:pithd1
gene id: 8128:pithd1
uniprot id: A0A669D7E7
names: Similarity
messages: Belongs to the PITHD1 family.

8128:LOC100690411
gene id: 8128:LOC100690411
uniprot id: A0A669C3H3
uniprot id: A0A669DQU1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

8128:ddx20
gene id: 8128:ddx20
uniprot id: I3K3H0
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:LOC100695760
gene id: 8128:LOC100695760
uniprot id: A0A669CXL8
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

8128:kdelc2
gene id: 8128:kdelc2
uniprot id: I3JY89
names: Similarity
messages: Belongs to the KDELC family.

8128:LOC100700758
gene id: 8128:LOC100700758
uniprot id: A0A669EZZ6
uniprot id: I3KFJ1
names: Similarity
messages: Belongs to the phospholipase D family.

8128:smo
gene id: 8128:smo
uniprot id: I3K0M9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:galt
gene id: 8128:galt
uniprot id: A0A669B7I3
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

8128:LOC100710389
gene id: 8128:LOC100710389
uniprot id: I3IYM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8128:lmbr1
gene id: 8128:lmbr1
uniprot id: I3JF56
names: Similarity
messages: Belongs to the LIMR family.

8128:LOC100706419
gene id: 8128:LOC100706419
uniprot id: A0A669BAC7
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8128:sfrp5
gene id: 8128:sfrp5
uniprot id: I3KPS6
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:il17rb
gene id: 8128:il17rb
uniprot id: A0A669F6L0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC106098144
gene id: 8128:LOC106098144
uniprot id: I3KYF7
names: Subcellular Location Annotation
messages: Membrane

8128:lhx4
gene id: 8128:lhx4
uniprot id: I3J0L0
names: Subcellular Location Annotation
messages: Nucleus

8128:lrig1
gene id: 8128:lrig1
uniprot id: A0A669DSX1
names: Subcellular Location Annotation
messages: Membrane

8128:rprm
gene id: 8128:rprm
uniprot id: I3KZ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reprimo family.
messages: Cytoplasm
messages: Membrane

8128:tamm41
gene id: 8128:tamm41
uniprot id: I3KA83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

8128:tlcd1
gene id: 8128:tlcd1
uniprot id: I3K622
names: Subcellular Location Annotation
messages: Membrane

8128:rad17
gene id: 8128:rad17
uniprot id: I3K8S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

8128:LOC100712573
gene id: 8128:LOC100712573
uniprot id: A0A0E3M3Y5
uniprot id: A0A669FAX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

8128:LOC100689964
gene id: 8128:LOC100689964
uniprot id: A0A669C7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

8128:LOC100703516
gene id: 8128:LOC100703516
uniprot id: A0A669EC11
names: Similarity
messages: Belongs to the globin family.

8128:LOC106099041
gene id: 8128:LOC106099041
uniprot id: A0A669BGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

8128:pde6g
gene id: 8128:pde6g
uniprot id: A0A669ENM5
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8128:LOC100692540
gene id: 8128:LOC100692540
uniprot id: I3K4V5
names: Similarity
messages: Belongs to the sorting nexin family.

8128:hgf
gene id: 8128:hgf
uniprot id: I3KCE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.
messages: extracellular space

8128:LOC100701786
gene id: 8128:LOC100701786
uniprot id: I3JW66
names: Similarity
messages: Belongs to the SPSB family.

8128:vps16
gene id: 8128:vps16
uniprot id: A0A669BMK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS16 family.
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: Vesicle

8128:LOC100707265
gene id: 8128:LOC100707265
uniprot id: I3IZM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

8128:fam69c
gene id: 8128:fam69c
uniprot id: I3K6T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

8128:ghrhr
gene id: 8128:ghrhr
uniprot id: I3J1A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8128:LOC100696631
gene id: 8128:LOC100696631
uniprot id: A0A669CM64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100706668
gene id: 8128:LOC100706668
uniprot id: I3JE51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:wdfy2
gene id: 8128:wdfy2
uniprot id: A0A669D3P2
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8128:entpd4
gene id: 8128:entpd4
uniprot id: I3K115
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8128:LOC100712082
gene id: 8128:LOC100712082
uniprot id: I3K223
names: Subcellular Location Annotation
messages: Membrane

8128:pth2r
gene id: 8128:pth2r
uniprot id: I3J9R4
names: Subcellular Location Annotation
messages: Membrane

8128:vipas39
gene id: 8128:vipas39
uniprot id: I3KS64
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Vesicle

8128:psat1
gene id: 8128:psat1
uniprot id: A0A669BJ95
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

8128:LOC100690604
gene id: 8128:LOC100690604
uniprot id: I3KMY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

8128:serpine2
gene id: 8128:serpine2
uniprot id: A0A669EQF9
uniprot id: I3JXD9
names: Similarity
messages: Belongs to the serpin family.

8128:trmt1l
gene id: 8128:trmt1l
uniprot id: A0A669BBG2
uniprot id: A0A669DPT5
uniprot id: I3JLW1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

8128:LOC100701219
gene id: 8128:LOC100701219
uniprot id: I3J3P5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:kdm3b
gene id: 8128:kdm3b
uniprot id: A0A669BEC8
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC109202854
gene id: 8128:LOC109202854
uniprot id: A0A669CU47
names: Similarity
messages: Belongs to the asteroid family.

8128:LOC109196579
gene id: 8128:LOC109196579
uniprot id: A0A669BX17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:LOC100708690
gene id: 8128:LOC100708690
uniprot id: I3KRL8
names: Similarity
messages: Belongs to the TEX28 family.

8128:LOC100702602
gene id: 8128:LOC100702602
uniprot id: I3J3G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space

8128:clspn
gene id: 8128:clspn
uniprot id: I3K7N2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100704650
gene id: 8128:LOC100704650
uniprot id: A0A669DS93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100708397
gene id: 8128:LOC100708397
uniprot id: A0A669AYT7
uniprot id: I3JRT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8128:LOC100709400
gene id: 8128:LOC100709400
uniprot id: A0A669DIC3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100698111
gene id: 8128:LOC100698111
uniprot id: I3KVS1
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

8128:LOC100705538
gene id: 8128:LOC100705538
uniprot id: I3J8S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC100690161
gene id: 8128:LOC100690161
uniprot id: I3KU67
names: Similarity
messages: Belongs to the JIP scaffold family.

8128:rpf1
gene id: 8128:rpf1
uniprot id: I3JKC7
names: Subcellular Location Annotation
messages: nucleolus

8128:LOC100704006
gene id: 8128:LOC100704006
uniprot id: I3K730
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

8128:LOC100705848
gene id: 8128:LOC100705848
uniprot id: I3JBX5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC100709940
gene id: 8128:LOC100709940
uniprot id: A0A669B439
names: Similarity
messages: Belongs to the pellino family.

8128:mthfr
gene id: 8128:mthfr
uniprot id: A0A669EMQ0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

8128:fam83d
gene id: 8128:fam83d
uniprot id: I3KWT3
names: Similarity
messages: Belongs to the FAM83 family.

8128:LOC100706525
gene id: 8128:LOC100706525
uniprot id: I3JZM9
names: Similarity
messages: Belongs to the arrestin family.

8128:LOC106097128
gene id: 8128:LOC106097128
uniprot id: A0A669C870
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100699795
gene id: 8128:LOC100699795
uniprot id: I3JY64
names: Similarity
messages: Belongs to the phosducin family.

8128:LOC100700729
gene id: 8128:LOC100700729
uniprot id: I3KSP4
names: Similarity
messages: Belongs to the LRRFIP family.

8128:cdc42ep5
gene id: 8128:cdc42ep5
uniprot id: A0A669BW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8128:LOC100695262
gene id: 8128:LOC100695262
uniprot id: I3JJD7
names: Similarity
messages: Belongs to the PRORSD1 family.

8128:LOC100703646
gene id: 8128:LOC100703646
uniprot id: I3K6A0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:atp5pd
gene id: 8128:atp5pd
uniprot id: I3J116
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

8128:LOC100702362
gene id: 8128:LOC100702362
uniprot id: A0A669DSC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

8128:LOC100695863
gene id: 8128:LOC100695863
uniprot id: A0A669F7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC100705944
gene id: 8128:LOC100705944
uniprot id: I3KR15
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100712349
gene id: 8128:LOC100712349
uniprot id: A0A669F372
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC102078622
gene id: 8128:LOC102078622
uniprot id: A0A669BUQ7
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100706353
gene id: 8128:LOC100706353
uniprot id: I3KZR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8128:lxn
gene id: 8128:lxn
uniprot id: I3J7B5
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

8128:LOC100703931
gene id: 8128:LOC100703931
uniprot id: A0A669EZQ7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:cfi
gene id: 8128:cfi
uniprot id: A0A669FAF3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:ccna2
gene id: 8128:ccna2
uniprot id: I3IYJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8128:sf3a1
gene id: 8128:sf3a1
uniprot id: I3JXP8
names: Subcellular Location Annotation
messages: Nucleus

8128:phactr2
gene id: 8128:phactr2
uniprot id: I3IWL7
uniprot id: I3IWL8
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

8128:LOC100703715
gene id: 8128:LOC100703715
uniprot id: A0A669CS67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:dync1h1
gene id: 8128:dync1h1
uniprot id: I3JBA9
uniprot id: I3JBB0
names: Similarity
messages: Belongs to the dynein heavy chain family.

8128:chrnb1
gene id: 8128:chrnb1
uniprot id: I3KQ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100705398
gene id: 8128:LOC100705398
uniprot id: A0A669EBC3
names: Similarity
messages: Belongs to the peptidase M14 family.

8128:p2ry1
gene id: 8128:p2ry1
uniprot id: I3KXU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100691340
gene id: 8128:LOC100691340
uniprot id: I3JD53
names: Subcellular Location Annotation
messages: Nucleus

8128:slc44a5
gene id: 8128:slc44a5
uniprot id: A0A669C290
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8128:cldn5
gene id: 8128:cldn5
uniprot id: I3KX91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:nhp2
gene id: 8128:nhp2
uniprot id: A0A669EPX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

8128:rexo4
gene id: 8128:rexo4
uniprot id: I3KVW1
names: Similarity
messages: Belongs to the REXO4 family.

8128:sars
gene id: 8128:sars
uniprot id: I3JRF3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

8128:acvr1c
gene id: 8128:acvr1c
uniprot id: I3JQY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8128:LOC100701807
gene id: 8128:LOC100701807
uniprot id: I3JE60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

8128:LOC100693419
gene id: 8128:LOC100693419
uniprot id: I3KYP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8128:LOC100694605
gene id: 8128:LOC100694605
uniprot id: I3KNZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

8128:LOC100709408
gene id: 8128:LOC100709408
uniprot id: A0A669EUL7
names: Similarity
messages: Belongs to the RRM Spen family.

8128:ncln
gene id: 8128:ncln
uniprot id: A0A669BUX4
names: Similarity
messages: Belongs to the nicastrin family.

8128:LOC100706574
gene id: 8128:LOC100706574
uniprot id: I3J4B7
names: Similarity
messages: Belongs to the intermediate filament family.

8128:rnf10
gene id: 8128:rnf10
uniprot id: A0A669E8Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF10 family.
messages: Cytoplasm

8128:LOC100692649
gene id: 8128:LOC100692649
uniprot id: I3J4C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8128:tmem132e
gene id: 8128:tmem132e
uniprot id: I3K6F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8128:gorab
gene id: 8128:gorab
uniprot id: I3JLY8
names: Similarity
messages: Belongs to the GORAB family.

8128:LOC100712429
gene id: 8128:LOC100712429
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:LOC100699343
gene id: 8128:LOC100699343
uniprot id: I3JH20
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:psmd6
gene id: 8128:psmd6
uniprot id: I3KX10
names: Similarity
messages: Belongs to the proteasome subunit S10 family.

8128:rnf7
gene id: 8128:rnf7
uniprot id: A0A669DNI6
names: Similarity
messages: Belongs to the RING-box family.

8128:LOC100710618
gene id: 8128:LOC100710618
uniprot id: I3K4Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100699569
gene id: 8128:LOC100699569
uniprot id: A0A669CN94
uniprot id: I3JFK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

8128:rbm17
gene id: 8128:rbm17
uniprot id: I3K1B1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

8128:pnpla6
gene id: 8128:pnpla6
uniprot id: A0A669ELB4
uniprot id: A0A669FBF8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:tmem144
gene id: 8128:tmem144
uniprot id: I3IY56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

8128:bmt2
gene id: 8128:bmt2
uniprot id: I3JQL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BMT2 family.
messages: Interacts with the GATOR1 complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine. Interacts with the KICSTOR complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine.
messages: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.

8128:dhh
gene id: 8128:dhh
uniprot id: A0A669DSS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

8128:usp49
gene id: 8128:usp49
uniprot id: I3KRU8
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:ift20
gene id: 8128:ift20
uniprot id: I3JWH9
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

8128:f5
gene id: 8128:f5
uniprot id: I3KHH1
names: Similarity
messages: Belongs to the multicopper oxidase family.

8128:LOC100697878
gene id: 8128:LOC100697878
uniprot id: I3KNM0
names: Similarity
messages: Belongs to the Luc7 family.

8128:atp10b
gene id: 8128:atp10b
uniprot id: I3K562
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8128:LOC100699350
gene id: 8128:LOC100699350
uniprot id: A0A669DNZ3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100695628
gene id: 8128:LOC100695628
uniprot id: A0A669D3F2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:cldn20
gene id: 8128:cldn20
uniprot id: A0A669DU30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:LOC100703857
gene id: 8128:LOC100703857
uniprot id: A0A669B1U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

8128:tubgcp3
gene id: 8128:tubgcp3
uniprot id: I3K301
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

8128:LOC100696847
gene id: 8128:LOC100696847
uniprot id: I3JVC2
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

8128:LOC100698493
gene id: 8128:LOC100698493
uniprot id: A0A669ET33
uniprot id: I3J7Y5
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

8128:LOC102077238
gene id: 8128:LOC102077238
uniprot id: I3KRZ5
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

8128:crtc1
gene id: 8128:crtc1
uniprot id: I3K462
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100702095
gene id: 8128:LOC100702095
uniprot id: A0A669DYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100704945
gene id: 8128:LOC100704945
uniprot id: I3IVW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8128:med18
gene id: 8128:med18
uniprot id: I3KGZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8128:wnt6
gene id: 8128:wnt6
uniprot id: I3J9F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8128:LOC100695303
gene id: 8128:LOC100695303
uniprot id: A0A669B6P3
uniprot id: I3JAD8
names: Subcellular Location Annotation
messages: extracellular matrix

8128:aff2
gene id: 8128:aff2
uniprot id: I3KFL5
names: Similarity
messages: Belongs to the AF4 family.

8128:dot1l
gene id: 8128:dot1l
uniprot id: A0A669BJT4
uniprot id: A0A669BMB3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus

8128:LOC109197370
gene id: 8128:LOC109197370
uniprot id: A0A669C289
names: Subcellular Location Annotation
messages: Membrane

8128:pltp
gene id: 8128:pltp
uniprot id: A0A669DK25
names: Similarity
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

8128:LOC100700551
gene id: 8128:LOC100700551
uniprot id: I3JLA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:ppp2r5d
gene id: 8128:ppp2r5d
uniprot id: I3JJB6
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8128:LOC100698257
gene id: 8128:LOC100698257
uniprot id: A0A669ENQ9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100710481
gene id: 8128:LOC100710481
uniprot id: A0A669D2L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC100710000
gene id: 8128:LOC100710000
uniprot id: A0A669BWR8
uniprot id: A0A669D5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Nucleus

8128:use1
gene id: 8128:use1
uniprot id: I3J097
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:fundc1
gene id: 8128:fundc1
uniprot id: I3KHC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

8128:ttc36
gene id: 8128:ttc36
uniprot id: I3JEF5
names: Similarity
messages: Belongs to the TTC36 family.

8128:ca14
gene id: 8128:ca14
uniprot id: I3JGR3
uniprot id: I3JGR4
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

8128:LOC100707615
gene id: 8128:LOC100707615
uniprot id: I3J3S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:txnrd2
gene id: 8128:txnrd2
uniprot id: I3KFL9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

8128:phax
gene id: 8128:phax
uniprot id: I3KZ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

8128:tnpo1
gene id: 8128:tnpo1
uniprot id: A0A669D5D7
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100700177
gene id: 8128:LOC100700177
uniprot id: I3IXG1
names: Subcellular Location Annotation
messages: sarcolemma

8128:cct8
gene id: 8128:cct8
uniprot id: I3JB44
uniprot id: I3JB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

8128:fabp2
gene id: 8128:fabp2
uniprot id: I3KM58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

8128:LOC100705530
gene id: 8128:LOC100705530
uniprot id: I3JBN5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:vps35
gene id: 8128:vps35
uniprot id: I3JD66
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

8128:clcn7
gene id: 8128:clcn7
uniprot id: I3KF32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

8128:dvl1
gene id: 8128:dvl1
uniprot id: I3KJK3
names: Similarity
messages: Belongs to the DSH family.

8128:pgap3
gene id: 8128:pgap3
uniprot id: A0A669DPA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Membrane

8128:LOC100692781
gene id: 8128:LOC100692781
uniprot id: I3J1B6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:bloc1s3
gene id: 8128:bloc1s3
uniprot id: I3JBQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S3 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).
messages: Cytoplasm

8128:LOC100705387
gene id: 8128:LOC100705387
uniprot id: A0A669CL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAMHD1 family.
messages: Chromosome

8128:LOC100708943
gene id: 8128:LOC100708943
uniprot id: A0A669E1M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC100702460
gene id: 8128:LOC100702460
uniprot id: I3K1R2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8128:s1pr1
gene id: 8128:s1pr1
uniprot id: I3KY83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC102077009
gene id: 8128:LOC102077009
uniprot id: A0A669B1Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

8128:cdc37
gene id: 8128:cdc37
uniprot id: A0A669DZ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

8128:fam72a
gene id: 8128:fam72a
uniprot id: I3KT40
names: Similarity
messages: Belongs to the FAM72 family.

8128:LOC100711249
gene id: 8128:LOC100711249
uniprot id: I3J3M1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

8128:LOC100707058
gene id: 8128:LOC100707058
uniprot id: I3KV01
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100699275
gene id: 8128:LOC100699275
uniprot id: I3IYR3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:LOC100694889
gene id: 8128:LOC100694889
uniprot id: I3K9U1
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

8128:LOC100710993
gene id: 8128:LOC100710993
uniprot id: A0A669CDW1
uniprot id: A0A669CH61
uniprot id: A0A669CM90
uniprot id: I3KKL7
names: Similarity
messages: Belongs to the BRAG family.

8128:LOC100707592
gene id: 8128:LOC100707592
uniprot id: A0A669EZA8
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

8128:LOC100702705
gene id: 8128:LOC100702705
uniprot id: I3JSZ3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:lg4h16orf58
gene id: 8128:lg4h16orf58
uniprot id: I3JU18
names: Similarity
messages: Belongs to the RUS1 family.

8128:osgepl1
gene id: 8128:osgepl1
uniprot id: I3KJ85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Mitochondrion
messages: Monomer.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

8128:LOC106096431
gene id: 8128:LOC106096431
uniprot id: A0A669BH60
uniprot id: A0A669C1K4
uniprot id: A0A669E7N1
uniprot id: A0A669EJZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

8128:LOC100706641
gene id: 8128:LOC100706641
uniprot id: I3JJQ1
names: Similarity
messages: Belongs to the SOGA family.

8128:tbc1d23
gene id: 8128:tbc1d23
uniprot id: A0A669ET95
uniprot id: I3JK59
names: Subcellular Location Annotation
messages: trans-Golgi network

8128:LOC102082028
gene id: 8128:LOC102082028
uniprot id: I3JTF1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100708303
gene id: 8128:LOC100708303
uniprot id: I3JJP7
names: Subcellular Location Annotation
messages: Cytoplasm

8128:rpl37
gene id: 8128:rpl37
uniprot id: I3JKS5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

8128:eif3b
gene id: 8128:eif3b
uniprot id: I3J5H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

8128:hps5
gene id: 8128:hps5
uniprot id: I3KES8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

8128:glut1
gene id: 8128:glut1
uniprot id: D2SYY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane
messages: Photoreceptor inner segment

8128:ppfia1
gene id: 8128:ppfia1
uniprot id: I3KEZ9
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

8128:rc3h1
gene id: 8128:rc3h1
uniprot id: I3JUH9
names: Subcellular Location Annotation
messages: P-body

8128:sft2d1
gene id: 8128:sft2d1
uniprot id: A0A669F172
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

8128:LOC102080527
gene id: 8128:LOC102080527
uniprot id: A0A669BXY2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8128:stoml2
gene id: 8128:stoml2
uniprot id: I3K5R5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8128:bbs10
gene id: 8128:bbs10
uniprot id: I3KCZ4
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

8128:LOC100702181
gene id: 8128:LOC100702181
uniprot id: A0A669BIQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

8128:LOC100706767
gene id: 8128:LOC100706767
uniprot id: I3JIY9
uniprot id: I3JIZ0
names: Similarity
messages: Belongs to the FAM131 family.

8128:LOC100709627
gene id: 8128:LOC100709627
uniprot id: I3JMD9
names: Subcellular Location Annotation
messages: cytoskeleton

8128:LOC100698007
gene id: 8128:LOC100698007
uniprot id: A0A669BKV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

8128:LOC100711727
gene id: 8128:LOC100711727
uniprot id: A0A669EWJ5
names: Similarity
messages: Belongs to the villin/gelsolin family.

8128:tmem47
gene id: 8128:tmem47
uniprot id: I3IZX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8128:pmvk
gene id: 8128:pmvk
uniprot id: I3IYT1
names: Subcellular Location Annotation
messages: cytosol

8128:LOC100698417
gene id: 8128:LOC100698417
uniprot id: I3KQ06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:ahcyl2
gene id: 8128:ahcyl2
uniprot id: I3KIY4
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

8128:LOC109201894
gene id: 8128:LOC109201894
uniprot id: A0A669DFV1
names: Similarity
messages: Belongs to the globin family.

8128:uckl1
gene id: 8128:uckl1
uniprot id: A0A669BE61
uniprot id: A0A669BEA6
uniprot id: A0A669CKT1
names: Similarity
messages: Belongs to the uridine kinase family.

8128:LOC100695498
gene id: 8128:LOC100695498
uniprot id: A0A669F8R8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100705715
gene id: 8128:LOC100705715
uniprot id: I3KEC4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100700539
gene id: 8128:LOC100700539
uniprot id: I3K4A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

8128:LOC100697611
gene id: 8128:LOC100697611
uniprot id: I3K3G5
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

8128:LOC100711983
gene id: 8128:LOC100711983
uniprot id: A0A669CWT3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:stn1
gene id: 8128:stn1
uniprot id: I3JQS4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

8128:hoxb8
gene id: 8128:hoxb8
uniprot id: A0A669E785
names: Subcellular Location Annotation
messages: Nucleus

8128:kcnj8
gene id: 8128:kcnj8
uniprot id: I3KNF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:LOC100705716
gene id: 8128:LOC100705716
uniprot id: I3K4I3
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8128:xdh
gene id: 8128:xdh
uniprot id: I3JR46
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Peroxisome

8128:LOC100697268
gene id: 8128:LOC100697268
uniprot id: I3K1V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

8128:LOC100694737
gene id: 8128:LOC100694737
uniprot id: A0A669BRG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

8128:ccnb1
gene id: 8128:ccnb1
uniprot id: I3K4W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8128:tshr
gene id: 8128:tshr
uniprot id: A0A669F7L8
uniprot id: Q98TF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

8128:ube2a
gene id: 8128:ube2a
uniprot id: A0A669EWB4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:LOC100702382
gene id: 8128:LOC100702382
uniprot id: I3JIK0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

8128:snx17
gene id: 8128:snx17
uniprot id: I3KDS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8128:LOC100701694
gene id: 8128:LOC100701694
uniprot id: I3KUQ3
names: Similarity
messages: Belongs to the TGF-beta family.

8128:cdc73
gene id: 8128:cdc73
uniprot id: A0A669DMW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC73 family.
messages: Nucleus

8128:greb1
gene id: 8128:greb1
uniprot id: I3KKK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

8128:madd
gene id: 8128:madd
uniprot id: A0A669E4L5
uniprot id: A0A669EVA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MADD family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8128:rps16
gene id: 8128:rps16
uniprot id: I3ITR9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

8128:LOC100703342
gene id: 8128:LOC100703342
uniprot id: I3JNA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

8128:LOC100699025
gene id: 8128:LOC100699025
uniprot id: A0A669AZN2
uniprot id: I3KBN5
names: Similarity
messages: Belongs to the DNase I family.

8128:LOC100693354
gene id: 8128:LOC100693354
uniprot id: A0A669B126
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8128:LOC100697792
gene id: 8128:LOC100697792
uniprot id: A0A669AYE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

8128:tcf7
gene id: 8128:tcf7
uniprot id: A0A669CF41
uniprot id: A0A669DID9
uniprot id: I3KKX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8128:mocs3
gene id: 8128:mocs3
uniprot id: A0A669C1D5
uniprot id: I3JMZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

8128:mars2
gene id: 8128:mars2
uniprot id: A0A669EYR4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8128:LOC100710794
gene id: 8128:LOC100710794
uniprot id: A0A669DHZ3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:terf1
gene id: 8128:terf1
uniprot id: I3KA17
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus

8128:luc7l3
gene id: 8128:luc7l3
uniprot id: I3J191
names: Similarity
messages: Belongs to the Luc7 family.

8128:serpine3
gene id: 8128:serpine3
uniprot id: I3KK73
names: Similarity
messages: Belongs to the serpin family.

8128:LOC100694260
gene id: 8128:LOC100694260
uniprot id: I3KLS9
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100703209
gene id: 8128:LOC100703209
uniprot id: A0A669D6Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:dhrs7b
gene id: 8128:dhrs7b
uniprot id: I3KTG3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100706047
gene id: 8128:LOC100706047
uniprot id: A0A669ENI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:prdm4
gene id: 8128:prdm4
uniprot id: I3KIX3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC102077511
gene id: 8128:LOC102077511
uniprot id: I3KP61
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100708026
gene id: 8128:LOC100708026
uniprot id: I3KXD4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100705489
gene id: 8128:LOC100705489
uniprot id: A0A669B8F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:ndufs7
gene id: 8128:ndufs7
uniprot id: I3K4B9
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

8128:LOC106096620
gene id: 8128:LOC106096620
uniprot id: A0A669D5A5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC102075892
gene id: 8128:LOC102075892
uniprot id: A0A669D5F7
names: Similarity
messages: Belongs to the peptidase C48 family.

8128:LOC100695763
gene id: 8128:LOC100695763
uniprot id: I3JAI4
names: Subcellular Location Annotation
messages: extracellular space

8128:inpp4b
gene id: 8128:inpp4b
uniprot id: I3KLG0
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

8128:chmp7
gene id: 8128:chmp7
uniprot id: I3JYA5
names: Similarity
messages: Belongs to the SNF7 family.

8128:tmco4
gene id: 8128:tmco4
uniprot id: A0A669EUI8
names: Similarity
messages: Belongs to the TMCO4 family.

8128:LOC100699619
gene id: 8128:LOC100699619
uniprot id: A0A669EYA1
names: Similarity
messages: Belongs to the Bcl-2 family.

8128:med13l
gene id: 8128:med13l
uniprot id: I3IUF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8128:LOC100704882
gene id: 8128:LOC100704882
uniprot id: A0A669B8B4
uniprot id: I3JQU0
names: Similarity
messages: Belongs to the WAL family.

8128:lin28b
gene id: 8128:lin28b
uniprot id: I3KBL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

8128:LOC100709772
gene id: 8128:LOC100709772
uniprot id: A0A669CCJ8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

8128:LOC100700639
gene id: 8128:LOC100700639
uniprot id: A0A669F323
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8128:LOC106097937
gene id: 8128:LOC106097937
uniprot id: A0A669CVU9
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

8128:ptk7
gene id: 8128:ptk7
uniprot id: I3JV77
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100710173
gene id: 8128:LOC100710173
uniprot id: A0A669DCC5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8128:LOC100709494
gene id: 8128:LOC100709494
uniprot id: I3KRN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

8128:sncg
gene id: 8128:sncg
uniprot id: A0A669D7L8
uniprot id: I3JIZ8
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.

8128:irf7
gene id: 8128:irf7
uniprot id: A0A669F082
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:rpgrip1l
gene id: 8128:rpgrip1l
uniprot id: I3KPB9
names: Similarity
messages: Belongs to the RPGRIP1 family.

8128:LOC100699762
gene id: 8128:LOC100699762
uniprot id: I3K4Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

8128:LOC100695963
gene id: 8128:LOC100695963
uniprot id: I3J777
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100712344
gene id: 8128:LOC100712344
uniprot id: A0A669CK87
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:tubgcp5
gene id: 8128:tubgcp5
uniprot id: I3JA83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

8128:nme6
gene id: 8128:nme6
uniprot id: A0A669E7S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8128:tpm1
gene id: 8128:tpm1
uniprot id: A0A669BV14
uniprot id: A0A669EPI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8128:LOC100697050
gene id: 8128:LOC100697050
uniprot id: I3K2W2
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8128:LOC100695394
gene id: 8128:LOC100695394
uniprot id: I3KMW0
uniprot id: I3KMW3
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8128:LOC100693391
gene id: 8128:LOC100693391
uniprot id: I3IUS7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:vma21
gene id: 8128:vma21
uniprot id: A0A669CGA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

8128:tp73
gene id: 8128:tp73
uniprot id: A0A669D526
uniprot id: A0A669DDD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Nucleus

8128:LOC100709787
gene id: 8128:LOC100709787
uniprot id: I3JR49
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:fgfbp2
gene id: 8128:fgfbp2
uniprot id: A0A669BQH4
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

8128:LOC100692852
gene id: 8128:LOC100692852
uniprot id: I3KXC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:LOC100692920
gene id: 8128:LOC100692920
uniprot id: I3J4C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8128:LOC100690579
gene id: 8128:LOC100690579
uniprot id: I3JE64
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:dcp2
gene id: 8128:dcp2
uniprot id: A0A669BXG0
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

8128:med26
gene id: 8128:med26
uniprot id: I3K481
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 26 family.
messages: Nucleus

8128:LOC100710201
gene id: 8128:LOC100710201
uniprot id: A0A669F3L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC102077352
gene id: 8128:LOC102077352
uniprot id: A0A669E031
names: Subcellular Location Annotation
messages: Membrane

8128:qprt
gene id: 8128:qprt
uniprot id: I3J5I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

8128:LOC100703698
gene id: 8128:LOC100703698
uniprot id: A0A669DRL7
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

8128:fam19a5
gene id: 8128:fam19a5
uniprot id: A0A669EYK0
names: Similarity
messages: Belongs to the TAFA family.

8128:gpr4
gene id: 8128:gpr4
uniprot id: A0A669ET06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100703249
gene id: 8128:LOC100703249
uniprot id: A0A669EX55
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8128:LOC100709284
gene id: 8128:LOC100709284
uniprot id: A0A669EDU4
uniprot id: I3JIB7
uniprot id: I3JIB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100694076
gene id: 8128:LOC100694076
uniprot id: A0A669EYP7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:sap18
gene id: 8128:sap18
uniprot id: I3K1N3
names: Function
names: Similarity
messages: Belongs to the SAP18 family.
messages: Involved in the tethering of the SIN3 complex to core histone proteins.

8128:klc2
gene id: 8128:klc2
uniprot id: A0A669DG02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8128:ezh1
gene id: 8128:ezh1
uniprot id: I3IY40
names: Subcellular Location Annotation
messages: Nucleus

8128:cwc15
gene id: 8128:cwc15
uniprot id: A0A669DUK0
names: Similarity
messages: Belongs to the CWC15 family.

8128:ghr1
gene id: 8128:ghr1
uniprot id: Q49B48
names: Function
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

8128:tnn
gene id: 8128:tnn
uniprot id: I3JUA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

8128:p2ry8
gene id: 8128:p2ry8
uniprot id: I3JIB4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:sgcg
gene id: 8128:sgcg
uniprot id: I3JD95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: cytoskeleton
messages: sarcolemma

8128:LOC100693723
gene id: 8128:LOC100693723
uniprot id: I3JWE7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8128:LOC100699650
gene id: 8128:LOC100699650
uniprot id: A0A669D0R9
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:cd247
gene id: 8128:cd247
uniprot id: I3JR30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

8128:sgcz
gene id: 8128:sgcz
uniprot id: A0A669BD41
uniprot id: I3KGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

8128:LOC100708499
gene id: 8128:LOC100708499
uniprot id: I3JY65
names: Similarity
messages: Belongs to the dickkopf family.

8128:LOC100712419
gene id: 8128:LOC100712419
uniprot id: A0A669DCB9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

8128:mrto4
gene id: 8128:mrto4
uniprot id: I3KA58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

8128:tnfaip3
gene id: 8128:tnfaip3
uniprot id: I3IWW3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:dyrk2
gene id: 8128:dyrk2
uniprot id: A0A669CGW2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8128:LOC100701565
gene id: 8128:LOC100701565
uniprot id: I3J825
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8128:LOC100691547
gene id: 8128:LOC100691547
uniprot id: A0A669B1J0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8128:ip6k1
gene id: 8128:ip6k1
uniprot id: I3J982
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8128:LOC100710729
gene id: 8128:LOC100710729
uniprot id: I3KG98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

8128:b3gnt3
gene id: 8128:b3gnt3
uniprot id: I3K445
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:phox2b
gene id: 8128:phox2b
uniprot id: I3IYN7
names: Subcellular Location Annotation
messages: Nucleus

8128:fam199x
gene id: 8128:fam199x
uniprot id: A0A669C7L7
names: Similarity
messages: Belongs to the FAM199 family.

8128:LOC100699612
gene id: 8128:LOC100699612
uniprot id: A0A669ET39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

8128:gal3st1
gene id: 8128:gal3st1
uniprot id: I3K7E4
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

8128:enpep
gene id: 8128:enpep
uniprot id: A0A669B7C2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homodimer; disulfide-linked.

8128:ackr4
gene id: 8128:ackr4
uniprot id: I3KXB5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:tet2
gene id: 8128:tet2
uniprot id: A0A669CSS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

8128:cct3
gene id: 8128:cct3
uniprot id: I3KDS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8128:LOC100707723
gene id: 8128:LOC100707723
uniprot id: I3K7F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8128:colgalt1
gene id: 8128:colgalt1
uniprot id: I3J0H9
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

8128:LOC100691455
gene id: 8128:LOC100691455
uniprot id: A0A669C6W5
names: Subcellular Location Annotation
messages: Synapse

8128:LOC100704877
gene id: 8128:LOC100704877
uniprot id: A0A669EXH1
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

8128:myo16
gene id: 8128:myo16
uniprot id: A0A669AW69
uniprot id: A0A669EBU8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100710420
gene id: 8128:LOC100710420
uniprot id: I3JHY9
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

8128:LOC100706519
gene id: 8128:LOC100706519
uniprot id: A0A669BIZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100690550
gene id: 8128:LOC100690550
uniprot id: I3K0W4
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100693140
gene id: 8128:LOC100693140
uniprot id: A0A669DIU7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC109201805
gene id: 8128:LOC109201805
uniprot id: A0A669B853
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

8128:dio3
gene id: 8128:dio3
uniprot id: Q9I966
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

8128:pdxp
gene id: 8128:pdxp
uniprot id: A0A669B1B3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

8128:sez6l2
gene id: 8128:sez6l2
uniprot id: I3KCE7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:sec63
gene id: 8128:sec63
uniprot id: A0A669BUM6
names: Subcellular Location Annotation
messages: Membrane

8128:foxb2
gene id: 8128:foxb2
uniprot id: I3KYU6
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100709969
gene id: 8128:LOC100709969
uniprot id: I3JUD3
names: Subcellular Location Annotation
messages: cytoskeleton

8128:supt3h
gene id: 8128:supt3h
uniprot id: A0A669EIU0
names: Subcellular Location Annotation
messages: Nucleus

8128:azin1
gene id: 8128:azin1
uniprot id: I3KHU2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

8128:LOC100693750
gene id: 8128:LOC100693750
uniprot id: A0A669BCE5
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:cpsf4
gene id: 8128:cpsf4
uniprot id: A0A669BZ71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

8128:LOC100703953
gene id: 8128:LOC100703953
uniprot id: A0A669EA08
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

8128:LOC100692367
gene id: 8128:LOC100692367
uniprot id: I3J1U2
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8128:rhbdl2
gene id: 8128:rhbdl2
uniprot id: I3KHD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

8128:nsmce1
gene id: 8128:nsmce1
uniprot id: I3KH73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus
messages: RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Involved in maintenance of genome integrity, DNA damage response and DNA repair.
messages: telomere

8128:LOC100710235
gene id: 8128:LOC100710235
uniprot id: I3K0M1
names: Subcellular Location Annotation
messages: Membrane

8128:sfxn1
gene id: 8128:sfxn1
uniprot id: A0A669F2N3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

8128:LOC100702614
gene id: 8128:LOC100702614
uniprot id: A0A669EMX8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100711140
gene id: 8128:LOC100711140
uniprot id: A0A669DKE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100699493
gene id: 8128:LOC100699493
uniprot id: A0A669E9P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane

8128:rnmt
gene id: 8128:rnmt
uniprot id: I3KDT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus

8128:coro2a
gene id: 8128:coro2a
uniprot id: I3KLM7
names: Similarity
messages: Belongs to the WD repeat coronin family.

8128:LOC100705311
gene id: 8128:LOC100705311
uniprot id: I3JE97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum axoneme

8128:gtf2a2
gene id: 8128:gtf2a2
uniprot id: A0A669D1S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

8128:LOC100701777
gene id: 8128:LOC100701777
uniprot id: I3IX58
names: Similarity
messages: Belongs to the intermediate filament family.

8128:dpyd
gene id: 8128:dpyd
uniprot id: A0A669BWS3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

8128:LOC100698932
gene id: 8128:LOC100698932
uniprot id: I3JL68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8128:cd63
gene id: 8128:cd63
uniprot id: A0A669C286
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100711616
gene id: 8128:LOC100711616
uniprot id: I3IYQ6
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100694155
gene id: 8128:LOC100694155
uniprot id: I3J630
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

8128:LOC100711404
gene id: 8128:LOC100711404
uniprot id: A0A669D183
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

8128:LOC100691191
gene id: 8128:LOC100691191
uniprot id: I3J5V0
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

8128:LOC100690432
gene id: 8128:LOC100690432
uniprot id: I3KIT5
names: Subcellular Location Annotation
messages: Membrane

8128:ppt2
gene id: 8128:ppt2
uniprot id: A0A669E3C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the palmitoyl-protein thioesterase family.
messages: Lysosome

8128:sostdc1
gene id: 8128:sostdc1
uniprot id: I3JHG1
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100690644
gene id: 8128:LOC100690644
uniprot id: A0A669BR63
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

8128:LOC100697822
gene id: 8128:LOC100697822
uniprot id: I3IVR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

8128:pigh
gene id: 8128:pigh
uniprot id: A0A669E4T1
names: Similarity
messages: Belongs to the PIGH family.

8128:LOC102078781
gene id: 8128:LOC102078781
uniprot id: A0A669EX61
names: Subcellular Location Annotation
messages: Membrane

8128:pola2
gene id: 8128:pola2
uniprot id: I3JCK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

8128:piwil2
gene id: 8128:piwil2
uniprot id: I3JYQ7
names: Similarity
messages: Belongs to the argonaute family.

8128:rpa3
gene id: 8128:rpa3
uniprot id: A0A669F1N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

8128:LOC100692791
gene id: 8128:LOC100692791
uniprot id: I3JNK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:rnf157
gene id: 8128:rnf157
uniprot id: A0A669E060
uniprot id: A0A669EUX1
uniprot id: I3KVL2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

8128:LOC100702118
gene id: 8128:LOC100702118
uniprot id: A0A669BK79
names: Subcellular Location Annotation
messages: Nucleus

8128:rnf40
gene id: 8128:rnf40
uniprot id: I3KVH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

8128:washc3
gene id: 8128:washc3
uniprot id: I3ITX6
names: Similarity
messages: Belongs to the CCDC53 family.

8128:LOC100693658
gene id: 8128:LOC100693658
uniprot id: I3J083
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100692029
gene id: 8128:LOC100692029
uniprot id: I3J7F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:dao
gene id: 8128:dao
uniprot id: A0A669DIA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

8128:LOC109203811
gene id: 8128:LOC109203811
uniprot id: A0A669DS91
names: Subcellular Location Annotation
messages: Membrane

8128:svop
gene id: 8128:svop
uniprot id: I3K6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8128:usp9x
gene id: 8128:usp9x
uniprot id: A0A669C712
uniprot id: A0A669EWD1
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:nudt21
gene id: 8128:nudt21
uniprot id: I3JED5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

8128:tac1
gene id: 8128:tac1
uniprot id: A0A669D9N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

8128:LOC100698323
gene id: 8128:LOC100698323
uniprot id: A0A669BAV6
uniprot id: A0A669BH73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus

8128:npc1l1
gene id: 8128:npc1l1
uniprot id: I3JXJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

8128:pbx3
gene id: 8128:pbx3
uniprot id: A0A669CIY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8128:fzd6
gene id: 8128:fzd6
uniprot id: I3IU79
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100692530
gene id: 8128:LOC100692530
uniprot id: A0A669D773
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8128:LOC100690812
gene id: 8128:LOC100690812
uniprot id: I3J0Y1
uniprot id: I3J0Y2
names: Similarity
messages: Belongs to the epsin family.

8128:got1
gene id: 8128:got1
uniprot id: A0A669C4C3
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

8128:ctso
gene id: 8128:ctso
uniprot id: I3IXW1
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:nol6
gene id: 8128:nol6
uniprot id: I3KG46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

8128:LOC100706618
gene id: 8128:LOC100706618
uniprot id: A0A669DI77
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

8128:LOC106096464
gene id: 8128:LOC106096464
uniprot id: A0A669BYX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane

8128:dbx1
gene id: 8128:dbx1
uniprot id: I3JJG6
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100709804
gene id: 8128:LOC100709804
uniprot id: A0A669EQN2
names: Similarity
messages: Belongs to the S-100 family.

8128:ficd
gene id: 8128:ficd
uniprot id: I3K6W5
names: Similarity
messages: Belongs to the fic family.

8128:foxp1
gene id: 8128:foxp1
uniprot id: I3KWP1
names: Subcellular Location Annotation
messages: Nucleus

8128:rfx2
gene id: 8128:rfx2
uniprot id: A0A669BY59
uniprot id: I3JUT5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100703837
gene id: 8128:LOC100703837
uniprot id: A0A669DCN8
names: Similarity
messages: Belongs to the UPF0046 family.

8128:mrps9
gene id: 8128:mrps9
uniprot id: I3K727
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

8128:penk
gene id: 8128:penk
uniprot id: A0A669F4Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

8128:dhrs11
gene id: 8128:dhrs11
uniprot id: I3K4P5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:glo1
gene id: 8128:glo1
uniprot id: A0A669CC49
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

8128:zcchc8
gene id: 8128:zcchc8
uniprot id: I3K6E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

8128:LOC100711007
gene id: 8128:LOC100711007
uniprot id: I3K5C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the janus family.
messages: Cytoplasm
messages: Exhibits phosphohistidine phosphatase activity.
messages: Monomer.

8128:pik3cg
gene id: 8128:pik3cg
uniprot id: A0A669D155
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8128:LOC100703707
gene id: 8128:LOC100703707
uniprot id: A0A669BGA2
names: Similarity
messages: Belongs to the FBPase class 1 family.

8128:ets1
gene id: 8128:ets1
uniprot id: A0A669BP67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:acot8
gene id: 8128:acot8
uniprot id: I3KWL7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8128:arpc2
gene id: 8128:arpc2
uniprot id: A0A669CER7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

8128:LOC100695749
gene id: 8128:LOC100695749
uniprot id: A0A669E8H9
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8128:syne3
gene id: 8128:syne3
uniprot id: I3JR94
names: Similarity
messages: Belongs to the nesprin family.

8128:LOC100706143
gene id: 8128:LOC100706143
uniprot id: I3JKZ1
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8128:kif3a
gene id: 8128:kif3a
uniprot id: I3KN69
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:zw10
gene id: 8128:zw10
uniprot id: I3KLC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZW10 family.
messages: kinetochore

8128:ctgf
gene id: 8128:ctgf
uniprot id: I3IWD0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100711542
gene id: 8128:LOC100711542
uniprot id: A0A669CJH1
uniprot id: A0A669DXB1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:lg5h12orf10
gene id: 8128:lg5h12orf10
uniprot id: I3JC73
names: Similarity
messages: Belongs to the MYG1 family.

8128:LOC100703351
gene id: 8128:LOC100703351
uniprot id: I3J8N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8128:fez2
gene id: 8128:fez2
uniprot id: A0A669BUQ6
uniprot id: A0A669EQY6
names: Similarity
messages: Belongs to the zygin family.

8128:uchl1
gene id: 8128:uchl1
uniprot id: Q8AV65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C12 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:pttg1
gene id: 8128:pttg1
uniprot id: I3J2T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100702997
gene id: 8128:LOC100702997
uniprot id: I3K1F7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100707466
gene id: 8128:LOC100707466
uniprot id: A0A669EC39
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

8128:dynlt1
gene id: 8128:dynlt1
uniprot id: I3K6L2
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8128:polr2i
gene id: 8128:polr2i
uniprot id: I3JD43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

8128:LOC100701932
gene id: 8128:LOC100701932
uniprot id: A0A669EWQ6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8128:kif3b
gene id: 8128:kif3b
uniprot id: I3IVI3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:LOC100694244
gene id: 8128:LOC100694244
uniprot id: A0A669C7B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8128:LOC100709923
gene id: 8128:LOC100709923
uniprot id: A0A669BNK0
names: Subcellular Location Annotation
messages: Secreted

8128:LOC100700730
gene id: 8128:LOC100700730
uniprot id: I3JWL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8128:six2
gene id: 8128:six2
uniprot id: I3IX50
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100694410
gene id: 8128:LOC100694410
uniprot id: I3KYL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

8128:LOC100690727
gene id: 8128:LOC100690727
uniprot id: A0A669B9U1
names: Similarity
messages: Belongs to the RRP1 family.

8128:mcoln3
gene id: 8128:mcoln3
uniprot id: I3JQN6
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8128:ifi30
gene id: 8128:ifi30
uniprot id: I3K4E6
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

8128:otub1
gene id: 8128:otub1
uniprot id: A0A669B986
names: Similarity
messages: Belongs to the peptidase C65 family.

8128:LOC100689896
gene id: 8128:LOC100689896
uniprot id: I3IYR6
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

8128:dirc2
gene id: 8128:dirc2
uniprot id: A0A669F8Y9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100711480
gene id: 8128:LOC100711480
uniprot id: I3KMX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

8128:LOC100705341
gene id: 8128:LOC100705341
uniprot id: A0A669B767
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:tmem106c
gene id: 8128:tmem106c
uniprot id: I3JRF7
names: Similarity
messages: Belongs to the TMEM106 family.

8128:LOC100690640
gene id: 8128:LOC100690640
uniprot id: I3J3J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

8128:slc8b1
gene id: 8128:slc8b1
uniprot id: A0A669D5H4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100697411
gene id: 8128:LOC100697411
uniprot id: A0A669F1X9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:ak3
gene id: 8128:ak3
uniprot id: A0A669CV18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

8128:LOC100704272
gene id: 8128:LOC100704272
uniprot id: A0A669AXN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

8128:LOC100698947
gene id: 8128:LOC100698947
uniprot id: A0A669CVY0
uniprot id: A0A669DPX9
names: Similarity
messages: Belongs to the copine family.

8128:arpin
gene id: 8128:arpin
uniprot id: I3JXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Arpin family.
messages: lamellipodium

8128:LOC100705283
gene id: 8128:LOC100705283
uniprot id: A0A669FA44
names: Subcellular Location Annotation
messages: Membrane

8128:syn2
gene id: 8128:syn2
uniprot id: A0A669BWJ1
names: Similarity
messages: Belongs to the synapsin family.

8128:LOC100699739
gene id: 8128:LOC100699739
uniprot id: A0A669BCW8
uniprot id: A0A669C4G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8128:fgf5
gene id: 8128:fgf5
uniprot id: A0A669C774
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heparin-binding growth factors family.
messages: Interacts with FGFR1 and FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
messages: Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.
messages: Secreted

8128:cenpt
gene id: 8128:cenpt
uniprot id: I3K0E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus

8128:LOC100692416
gene id: 8128:LOC100692416
uniprot id: A0A669CRX2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

8128:LOC100703700
gene id: 8128:LOC100703700
uniprot id: A0A669B5M8
uniprot id: I3IXH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

8128:ccnl1
gene id: 8128:ccnl1
uniprot id: A0A669B6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin L subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus speckle
messages: nucleoplasm

8128:creg2
gene id: 8128:creg2
uniprot id: I3K9W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

8128:hcrtr2
gene id: 8128:hcrtr2
uniprot id: I3JTL6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100707493
gene id: 8128:LOC100707493
uniprot id: A0A669CU13
uniprot id: A0A669E3Q9
uniprot id: A0A669F6F6
uniprot id: A0A669F9Q0
uniprot id: I3K1G4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

8128:arsj
gene id: 8128:arsj
uniprot id: I3JDD5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8128:LOC100700962
gene id: 8128:LOC100700962
uniprot id: A0A669D0A1
names: Similarity
messages: Belongs to the cornifelin family.

8128:prdm13
gene id: 8128:prdm13
uniprot id: I3IU48
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100690289
gene id: 8128:LOC100690289
uniprot id: I3KCG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8128:ric8b
gene id: 8128:ric8b
uniprot id: I3KBT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

8128:trhde
gene id: 8128:trhde
uniprot id: A0A669F9I6
names: Similarity
messages: Belongs to the peptidase M1 family.

8128:LOC100696049
gene id: 8128:LOC100696049
uniprot id: I3JWH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:foxo3
gene id: 8128:foxo3
uniprot id: I3K6H3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100692305
gene id: 8128:LOC100692305
uniprot id: I3J5T5
names: Similarity
messages: Belongs to the stathmin family.

8128:LOC100691947
gene id: 8128:LOC100691947
uniprot id: A0A669BI95
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8128:srp54
gene id: 8128:srp54
uniprot id: A0A669DBQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Nucleus speckle
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

8128:mtfmt
gene id: 8128:mtfmt
uniprot id: I3KBC2
names: Similarity
messages: Belongs to the Fmt family.

8128:LOC100697381
gene id: 8128:LOC100697381
uniprot id: A0A669D0Q3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100694913
gene id: 8128:LOC100694913
uniprot id: A0A669D125
uniprot id: A0A669F021
names: Similarity
messages: Belongs to the peptidase M10A family.

8128:LOC100708206
gene id: 8128:LOC100708206
uniprot id: A0A669CJQ4
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:LOC100691772
gene id: 8128:LOC100691772
uniprot id: I3KVL0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:LOC100707636
gene id: 8128:LOC100707636
uniprot id: I3JGR0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8128:anapc10
gene id: 8128:anapc10
uniprot id: I3K0T8
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

8128:cript
gene id: 8128:cript
uniprot id: A0A669CY41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

8128:ubald1
gene id: 8128:ubald1
uniprot id: I3KUT8
names: Similarity
messages: Belongs to the UBALD family.

8128:LOC100708656
gene id: 8128:LOC100708656
uniprot id: A0A669CI72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

8128:naa60
gene id: 8128:naa60
uniprot id: I3JHB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

8128:LOC100696176
gene id: 8128:LOC100696176
uniprot id: A0A669EVU9
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

8128:slc35e3
gene id: 8128:slc35e3
uniprot id: I3KNI0
names: Subcellular Location Annotation
messages: Membrane

8128:dph5
gene id: 8128:dph5
uniprot id: I3JLQ4
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

8128:LOC100707068
gene id: 8128:LOC100707068
uniprot id: I3KD77
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100703479
gene id: 8128:LOC100703479
uniprot id: I3KFF4
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100699470
gene id: 8128:LOC100699470
uniprot id: I3JBE5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100703194
gene id: 8128:LOC100703194
uniprot id: I3KQM9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

8128:LOC100689836
gene id: 8128:LOC100689836
uniprot id: I3J3G0
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8128:LOC100699532
gene id: 8128:LOC100699532
uniprot id: A0A669DGK5
uniprot id: I3KJT8
names: Subcellular Location Annotation
messages: Nucleus

8128:parp4
gene id: 8128:parp4
uniprot id: A0A669BHE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

8128:adam9
gene id: 8128:adam9
uniprot id: A0A669EFI6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:cast
gene id: 8128:cast
uniprot id: A0A669BSY3
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I27 (calpastatin) family.
messages: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.

8128:eaf2
gene id: 8128:eaf2
uniprot id: A0A669C6R4
names: Similarity
messages: Belongs to the EAF family.

8128:phyhipl
gene id: 8128:phyhipl
uniprot id: A0A669DKY4
uniprot id: A0A669E929
names: Similarity
messages: Belongs to the PHYHIP family.

8128:frk
gene id: 8128:frk
uniprot id: I3JZI4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:lg22h18orf21
gene id: 8128:lg22h18orf21
uniprot id: A0A669AZZ2
names: Similarity
messages: Belongs to the UPF0711 family.

8128:ciao2a
gene id: 8128:ciao2a
uniprot id: A0A669C5K1
names: Similarity
messages: Belongs to the MIP18 family.

8128:terf2ip
gene id: 8128:terf2ip
uniprot id: I3KA69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Nucleus
messages: telomere

8128:LOC100707523
gene id: 8128:LOC100707523
uniprot id: A0A669CGI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

8128:LOC100692694
gene id: 8128:LOC100692694
uniprot id: A0A669BY57
uniprot id: A0A669DBQ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

8128:LOC100691107
gene id: 8128:LOC100691107
uniprot id: I3JZ62
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

8128:LOC100712552
gene id: 8128:LOC100712552
uniprot id: A0A669BTX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

8128:LOC102079731
gene id: 8128:LOC102079731
uniprot id: I3KXN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:donson
gene id: 8128:donson
uniprot id: I3JBD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DONSON family.
messages: Nucleus

8128:LOC100691074
gene id: 8128:LOC100691074
uniprot id: A0A669C5S5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:dolpp1
gene id: 8128:dolpp1
uniprot id: I3JKA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

8128:LOC100706150
gene id: 8128:LOC100706150
uniprot id: I3J698
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

8128:LOC100693117
gene id: 8128:LOC100693117
uniprot id: A0A669BKN4
uniprot id: A0A669C0L3
names: Similarity
messages: Belongs to the TCF/LEF family.

8128:LOC102082339
gene id: 8128:LOC102082339
uniprot id: I3KR24
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100709859
gene id: 8128:LOC100709859
uniprot id: I3KSZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:eya4
gene id: 8128:eya4
uniprot id: A0A669EI72
uniprot id: A0A669EUR1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Nucleus

8128:acadvl
gene id: 8128:acadvl
uniprot id: I3JB46
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8128:med17
gene id: 8128:med17
uniprot id: I3IYP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8128:LOC100709898
gene id: 8128:LOC100709898
uniprot id: I3JME1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

8128:ildr1
gene id: 8128:ildr1
uniprot id: I3K9M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8128:mrpl43
gene id: 8128:mrpl43
uniprot id: A0A669B7C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

8128:LOC102081637
gene id: 8128:LOC102081637
uniprot id: A0A669BDC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:rbp7
gene id: 8128:rbp7
uniprot id: A0A669B611
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8128:LOC100699499
gene id: 8128:LOC100699499
uniprot id: A0A669B5K9
names: Subcellular Location Annotation
messages: extracellular space

8128:caskin2
gene id: 8128:caskin2
uniprot id: I3KTW6
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100707385
gene id: 8128:LOC100707385
uniprot id: I3KQK0
names: Similarity
messages: Belongs to the BRINP family.

8128:LOC100534558
gene id: 8128:LOC100534558
uniprot id: Q1KL30
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8128:adamts16
gene id: 8128:adamts16
uniprot id: I3JJD5
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:ap2s1
gene id: 8128:ap2s1
uniprot id: A0A669AW68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: coated pit

8128:aars
gene id: 8128:aars
uniprot id: I3JYY5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

8128:LOC100705280
gene id: 8128:LOC100705280
uniprot id: A0A669AV73
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:LOC100708276
gene id: 8128:LOC100708276
uniprot id: I3JE96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100692292
gene id: 8128:LOC100692292
uniprot id: I3KDZ9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:LOC100710292
gene id: 8128:LOC100710292
uniprot id: A0A669BPW0
uniprot id: A0A669ED75
uniprot id: I3K0E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8128:LOC100696521
gene id: 8128:LOC100696521
uniprot id: I3IXT3
names: Subcellular Location Annotation
messages: Membrane

8128:isca1
gene id: 8128:isca1
uniprot id: A0A669E4N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

8128:osbpl6
gene id: 8128:osbpl6
uniprot id: A0A669DIY2
names: Similarity
messages: Belongs to the OSBP family.

8128:LOC100699482
gene id: 8128:LOC100699482
uniprot id: I3KNR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8128:LOC100697834
gene id: 8128:LOC100697834
uniprot id: I3J8P6
names: Similarity
messages: Belongs to the FMO family.

8128:LOC100712231
gene id: 8128:LOC100712231
uniprot id: A0A669D3L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:sap30l
gene id: 8128:sap30l
uniprot id: I3K696
names: Similarity
messages: Belongs to the SAP30 family.

8128:ints11
gene id: 8128:ints11
uniprot id: A0A669BNI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Nucleus

8128:ost4
gene id: 8128:ost4
uniprot id: A0A669EEL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:vwc2l
gene id: 8128:vwc2l
uniprot id: I3J8V5
names: Subcellular Location Annotation
messages: Synapse

8128:LOC100701071
gene id: 8128:LOC100701071
uniprot id: A0A669CWA8
uniprot id: I3K4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC100712370
gene id: 8128:LOC100712370
uniprot id: A0A669BTY0
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8128:LOC100696670
gene id: 8128:LOC100696670
uniprot id: I3KMQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

8128:LOC100700200
gene id: 8128:LOC100700200
uniprot id: I3J7V1
names: Subcellular Location Annotation
messages: Nucleus

8128:stxbp2
gene id: 8128:stxbp2
uniprot id: I3J0C2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8128:nup58
gene id: 8128:nup58
uniprot id: A0A669CL99
uniprot id: A0A669EWG7
names: Subcellular Location Annotation
messages: nuclear pore complex

8128:LOC100692910
gene id: 8128:LOC100692910
uniprot id: A0A669EX46
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8128:ubac2
gene id: 8128:ubac2
uniprot id: A0A669D565
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100707970
gene id: 8128:LOC100707970
uniprot id: A0A669DQG8
uniprot id: A0A669EF20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8128:slco5a1
gene id: 8128:slco5a1
uniprot id: I3K9V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8128:LOC100694302
gene id: 8128:LOC100694302
uniprot id: A0A669DF56
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:fam102b
gene id: 8128:fam102b
uniprot id: A0A669C110
names: Similarity
messages: Belongs to the FAM102 family.

8128:timm21
gene id: 8128:timm21
uniprot id: I3KA90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

8128:LOC100695768
gene id: 8128:LOC100695768
uniprot id: I3JIV6
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8128:LOC100711696
gene id: 8128:LOC100711696
uniprot id: I3KVC3
names: Similarity
messages: Belongs to the serpin family.

8128:cfap206
gene id: 8128:cfap206
uniprot id: I3IZL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP206 family.
messages: cilium axoneme
messages: cilium basal body

8128:tmem134
gene id: 8128:tmem134
uniprot id: I3KBB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Membrane

8128:polr2j
gene id: 8128:polr2j
uniprot id: I3IUP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

8128:LOC100698337
gene id: 8128:LOC100698337
uniprot id: A0A669CJF8
names: Similarity
messages: Belongs to the FAM110 family.

8128:ddx18
gene id: 8128:ddx18
uniprot id: I3JM49
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.

8128:kiz
gene id: 8128:kiz
uniprot id: I3JN07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kizuna family.
messages: Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
messages: centrosome
messages: cilium basal body

8128:LOC100691542
gene id: 8128:LOC100691542
uniprot id: A0A669CK88
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin Y subfamily.

8128:LOC100700254
gene id: 8128:LOC100700254
uniprot id: A0A669E2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8128:ugdh
gene id: 8128:ugdh
uniprot id: A0A669C260
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

8128:LOC100702641
gene id: 8128:LOC100702641
uniprot id: I3J854
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8128:tob2
gene id: 8128:tob2
uniprot id: A0A669EUC2
names: Similarity
messages: Belongs to the BTG family.

8128:LOC100702570
gene id: 8128:LOC100702570
uniprot id: I3KN98
names: Similarity
messages: Belongs to the DNase I family.

8128:LOC100691757
gene id: 8128:LOC100691757
uniprot id: I3KEU8
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

8128:LOC102076024
gene id: 8128:LOC102076024
uniprot id: I3K9J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8128:LOC100710470
gene id: 8128:LOC100710470
uniprot id: A0A669E7D5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100709865
gene id: 8128:LOC100709865
uniprot id: I3KZU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:znf532
gene id: 8128:znf532
uniprot id: I3JLF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

8128:LOC100704815
gene id: 8128:LOC100704815
uniprot id: A0A669ETU5
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:mus81
gene id: 8128:mus81
uniprot id: I3ITV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

8128:LOC100709771
gene id: 8128:LOC100709771
uniprot id: I3JAI6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC102080805
gene id: 8128:LOC102080805
uniprot id: A0A669CFI9
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

8128:sucnr1
gene id: 8128:sucnr1
uniprot id: I3J6K6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:cenpi
gene id: 8128:cenpi
uniprot id: A0A669BFY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

8128:tfb2m
gene id: 8128:tfb2m
uniprot id: I3KKE4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

8128:hoxc4
gene id: 8128:hoxc4
uniprot id: I3K2S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8128:LOC100701625
gene id: 8128:LOC100701625
uniprot id: A0A669BXI5
names: Similarity
messages: Belongs to the TGF-beta family.

8128:LOC102082014
gene id: 8128:LOC102082014
uniprot id: I3JA62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

8128:LOC100694084
gene id: 8128:LOC100694084
uniprot id: A0A669C4Z5
uniprot id: I3K849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

8128:LOC100699157
gene id: 8128:LOC100699157
uniprot id: I3KDK0
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC100706367
gene id: 8128:LOC100706367
uniprot id: A0A669F7B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

8128:mdk
gene id: 8128:mdk
uniprot id: I3KPB0
names: Similarity
messages: Belongs to the pleiotrophin family.

8128:LOC100689795
gene id: 8128:LOC100689795
uniprot id: A0A669CDM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

8128:dlx3
gene id: 8128:dlx3
uniprot id: A0A669CFE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8128:LOC100703074
gene id: 8128:LOC100703074
uniprot id: A0A669F506
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

8128:LOC100709375
gene id: 8128:LOC100709375
uniprot id: A0A669DXF2
uniprot id: I3JLP4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

8128:slc30a9
gene id: 8128:slc30a9
uniprot id: I3J295
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Membrane
messages: Nucleus
messages: Vesicle

8128:LOC109202463
gene id: 8128:LOC109202463
uniprot id: A0A669D266
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

8128:lg23h19orf70
gene id: 8128:lg23h19orf70
uniprot id: A0A669CWS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

8128:meis1
gene id: 8128:meis1
uniprot id: A0A669ENP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8128:lhfpl2
gene id: 8128:lhfpl2
uniprot id: A0A669DBF8
names: Subcellular Location Annotation
messages: Membrane

8128:ipo11
gene id: 8128:ipo11
uniprot id: I3KD68
names: Subcellular Location Annotation
messages: Cytoplasm

8128:trip13
gene id: 8128:trip13
uniprot id: I3J4L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.

8128:LOC100695275
gene id: 8128:LOC100695275
uniprot id: I3K635
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100695903
gene id: 8128:LOC100695903
uniprot id: I3IY91
names: Similarity
messages: Belongs to the TGF-beta family.

8128:LOC100691448
gene id: 8128:LOC100691448
uniprot id: I3J3P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

8128:homer3
gene id: 8128:homer3
uniprot id: I3K4I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

8128:kif22
gene id: 8128:kif22
uniprot id: I3JZZ1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:LOC100707752
gene id: 8128:LOC100707752
uniprot id: A0A669DS09
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

8128:LOC102077341
gene id: 8128:LOC102077341
uniprot id: A0A669CJ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. CNC subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8128:LOC109202907
gene id: 8128:LOC109202907
uniprot id: A0A669DBE6
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100702561
gene id: 8128:LOC100702561
uniprot id: I3ITU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:LOC100702792
gene id: 8128:LOC100702792
uniprot id: A0A669DBU0
uniprot id: A0A669F4J0
uniprot id: I3J9U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

8128:stat1
gene id: 8128:stat1
uniprot id: A0A669ES78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100696912
gene id: 8128:LOC100696912
uniprot id: A0A669CL39
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin Y subfamily.

8128:LOC100704534
gene id: 8128:LOC100704534
uniprot id: I3J8A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:vac14
gene id: 8128:vac14
uniprot id: I3KYP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAC14 family.
messages: Endosome membrane
messages: Microsome membrane

8128:LOC100690370
gene id: 8128:LOC100690370
uniprot id: I3J8F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8128:LOC102081250
gene id: 8128:LOC102081250
uniprot id: I3JX74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

8128:LOC100709989
gene id: 8128:LOC100709989
uniprot id: I3KHG7
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100695523
gene id: 8128:LOC100695523
uniprot id: I3JWG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:LOC102079422
gene id: 8128:LOC102079422
uniprot id: I3JXR0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:slc6a9
gene id: 8128:slc6a9
uniprot id: A0A669DHK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100709727
gene id: 8128:LOC100709727
uniprot id: I3K7H9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC102081783
gene id: 8128:LOC102081783
uniprot id: A0A669DY95
names: Subcellular Location Annotation
messages: Membrane

8128:atp6v1g1
gene id: 8128:atp6v1g1
uniprot id: A0A669CF55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8128:LOC100706139
gene id: 8128:LOC100706139
uniprot id: I3J7B2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:sin3a
gene id: 8128:sin3a
uniprot id: I3K4X6
names: Subcellular Location Annotation
messages: Nucleus

8128:slc30a7
gene id: 8128:slc30a7
uniprot id: I3JLP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Homooligomer.
messages: Membrane
messages: trans-Golgi network membrane

8128:LOC100701473
gene id: 8128:LOC100701473
uniprot id: I3JD69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8128:upf3b
gene id: 8128:upf3b
uniprot id: I3J2T5
names: Similarity
messages: Belongs to the RENT3 family.

8128:LOC100707261
gene id: 8128:LOC100707261
uniprot id: I3JCG3
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8128:LOC100699487
gene id: 8128:LOC100699487
uniprot id: I3KSG6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100697446
gene id: 8128:LOC100697446
uniprot id: I3K6S4
names: Subcellular Location Annotation
messages: Nucleus

8128:eml4
gene id: 8128:eml4
uniprot id: A0A669CMZ5
names: Similarity
messages: Belongs to the WD repeat EMAP family.

8128:snrpd3
gene id: 8128:snrpd3
uniprot id: I3J7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

8128:kcnc2
gene id: 8128:kcnc2
uniprot id: A0A669CN28
uniprot id: A0A669F970
names: Subcellular Location Annotation
messages: Membrane

8128:rabggtb
gene id: 8128:rabggtb
uniprot id: A0A669AZC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

8128:LOC100702940
gene id: 8128:LOC100702940
uniprot id: I3KFB7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: extracellular space

8128:LOC100703033
gene id: 8128:LOC100703033
uniprot id: I3KBN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:hbs1l
gene id: 8128:hbs1l
uniprot id: A0A669EGN9
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Interacts with the SKI complex.

8128:srsf5
gene id: 8128:srsf5
uniprot id: A0A669F2B6
names: Similarity
messages: Belongs to the splicing factor SR family.

8128:dlgap2
gene id: 8128:dlgap2
uniprot id: A0A669DTC6
names: Similarity
messages: Belongs to the SAPAP family.

8128:fbxo31
gene id: 8128:fbxo31
uniprot id: A0A669DTR3
uniprot id: I3KBP1
names: Similarity
names: Subunit
messages: Belongs to the FBXO31 family.
messages: Part of a SCF (SKP1-cullin-F-box) protein ligase complex.

8128:LOC100694789
gene id: 8128:LOC100694789
uniprot id: A0A669BJS5
uniprot id: A0A669EZA5
uniprot id: I3JKJ5
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8128:LOC100702473
gene id: 8128:LOC100702473
uniprot id: I3K6P1
names: Similarity
messages: Belongs to the TGF-beta family.

8128:LOC100699567
gene id: 8128:LOC100699567
uniprot id: I3KBV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

8128:LOC100711554
gene id: 8128:LOC100711554
uniprot id: A0A669EPC8
names: Similarity
messages: Belongs to the cytochrome b5 family.

8128:LOC100702791
gene id: 8128:LOC100702791
uniprot id: I3JPY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8128:hnf4a
gene id: 8128:hnf4a
uniprot id: A0A669DAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:LOC100701041
gene id: 8128:LOC100701041
uniprot id: A0A669CY78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

8128:LOC100693547
gene id: 8128:LOC100693547
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:LOC100691206
gene id: 8128:LOC100691206
uniprot id: I3KUU2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100704256
gene id: 8128:LOC100704256
uniprot id: I3KCZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:ssbp1
gene id: 8128:ssbp1
uniprot id: A0A669F4S5
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

8128:bcl9
gene id: 8128:bcl9
uniprot id: I3KG77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

8128:LOC100707873
gene id: 8128:LOC100707873
uniprot id: A0A669C8E0
uniprot id: I3KEA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

8128:LOC100695482
gene id: 8128:LOC100695482
uniprot id: A0A669DC57
names: Similarity
messages: Belongs to the actin family.

8128:LOC102081219
gene id: 8128:LOC102081219
uniprot id: I3JDG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

8128:psme3
gene id: 8128:psme3
uniprot id: I3KPF7
names: Similarity
messages: Belongs to the PA28 family.

8128:LOC100701549
gene id: 8128:LOC100701549
uniprot id: I3JYU2
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8128:LOC100694563
gene id: 8128:LOC100694563
uniprot id: A0A669C2Y3
names: Similarity
messages: Belongs to the PP2C family.

8128:hexb
gene id: 8128:hexb
uniprot id: A0A669DPT2
uniprot id: I3JYX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

8128:gstcd
gene id: 8128:gstcd
uniprot id: I3KLV6
names: Similarity
messages: Belongs to the GSTCD family.

8128:uba5
gene id: 8128:uba5
uniprot id: A0A669CLC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
messages: Golgi apparatus

8128:fam32a
gene id: 8128:fam32a
uniprot id: I3J1Z8
names: Similarity
messages: Belongs to the FAM32 family.

8128:cenph
gene id: 8128:cenph
uniprot id: I3K852
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

8128:galnt17
gene id: 8128:galnt17
uniprot id: I3JEU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:rsrp1
gene id: 8128:rsrp1
uniprot id: I3JN98
names: Similarity
messages: Belongs to the RSRP family.

8128:tmtc4
gene id: 8128:tmtc4
uniprot id: I3JI76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8128:loxl3
gene id: 8128:loxl3
uniprot id: A0A669BNP6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8128:LOC102076776
gene id: 8128:LOC102076776
uniprot id: I3JJ83
names: Similarity
messages: Belongs to the MHC class I family.

8128:LOC106096880
gene id: 8128:LOC106096880
uniprot id: A0A669D350
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100697787
gene id: 8128:LOC100697787
uniprot id: I3J5W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8128:LOC100692461
gene id: 8128:LOC100692461
uniprot id: I3KXC9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100702133
gene id: 8128:LOC100702133
uniprot id: A0A669BXP4
names: Subcellular Location Annotation
messages: Nucleus

8128:ankzf1
gene id: 8128:ankzf1
uniprot id: I3JR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

8128:LOC100708122
gene id: 8128:LOC100708122
uniprot id: I3KIB1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100696190
gene id: 8128:LOC100696190
uniprot id: A0A669B3N1
names: Similarity
messages: Belongs to the TMEM14 family.

8128:ndufaf3
gene id: 8128:ndufaf3
uniprot id: A0A669D9N5
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

8128:mis18a
gene id: 8128:mis18a
uniprot id: A0A669CD33
names: Function
names: Subcellular Location Annotation
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

8128:ift122
gene id: 8128:ift122
uniprot id: A0A669B4A3
names: Subcellular Location Annotation
messages: cilium

8128:LOC100698085
gene id: 8128:LOC100698085
uniprot id: I3J771
uniprot id: I3J772
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

8128:LOC100700541
gene id: 8128:LOC100700541
uniprot id: I3IXF4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100710579
gene id: 8128:LOC100710579
uniprot id: A0A669C2R6
uniprot id: A0A669DJ08
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8128:gba2
gene id: 8128:gba2
uniprot id: A0A669CIP9
names: Function
names: Similarity
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

8128:rab32
gene id: 8128:rab32
uniprot id: I3K6W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8128:LOC100708259
gene id: 8128:LOC100708259
uniprot id: I3JMW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC50/LEM3 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: secretory vesicle membrane

8128:LOC100698360
gene id: 8128:LOC100698360
uniprot id: I3KPJ9
names: Similarity
messages: Belongs to the pleurocidin family.

8128:itih2
gene id: 8128:itih2
uniprot id: A0A669C0R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

8128:LOC100697177
gene id: 8128:LOC100697177
uniprot id: I3J197
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Membrane

8128:LOC100707762
gene id: 8128:LOC100707762
uniprot id: A0A669DYE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

8128:LOC100704493
gene id: 8128:LOC100704493
uniprot id: A0A669FA96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8128:mrpl11
gene id: 8128:mrpl11
uniprot id: A0A669DLR7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

8128:LOC100698262
gene id: 8128:LOC100698262
uniprot id: I3KKI7
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

8128:pkp2
gene id: 8128:pkp2
uniprot id: A0A669ENL3
names: Similarity
messages: Belongs to the beta-catenin family.

8128:icmt
gene id: 8128:icmt
uniprot id: I3KNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:tmc8
gene id: 8128:tmc8
uniprot id: I3KRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

8128:rab9a
gene id: 8128:rab9a
uniprot id: I3KXY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

8128:hoga1
gene id: 8128:hoga1
uniprot id: I3IUP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.

8128:LOC100703874
gene id: 8128:LOC100703874
uniprot id: A0A669CL15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

8128:lasp1
gene id: 8128:lasp1
uniprot id: A0A669ELI5
names: Function
names: Subcellular Location Annotation
messages: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
messages: cell cortex
messages: cytoskeleton

8128:ippk
gene id: 8128:ippk
uniprot id: A0A669DEZ1
uniprot id: I3IVG3
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

8128:LOC100691835
gene id: 8128:LOC100691835
uniprot id: I3KAV8
names: Subcellular Location Annotation
messages: Secreted

8128:hnrnpul1
gene id: 8128:hnrnpul1
uniprot id: I3J855
names: Subcellular Location Annotation
messages: Nucleus

8128:mff
gene id: 8128:mff
uniprot id: A0A669ESB6
uniprot id: I3JDW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

8128:LOC100703802
gene id: 8128:LOC100703802
uniprot id: I3J2Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8128:LOC100711350
gene id: 8128:LOC100711350
uniprot id: I3JRR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

8128:LOC109195630
gene id: 8128:LOC109195630
uniprot id: I3KZ77
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:bbox1
gene id: 8128:bbox1
uniprot id: I3JET2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
messages: Cytoplasm

8128:olfm2
gene id: 8128:olfm2
uniprot id: A0A669ERK4
uniprot id: I3IUH3
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8128:LOC100698638
gene id: 8128:LOC100698638
uniprot id: I3JW63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:nampt
gene id: 8128:nampt
uniprot id: A0A669C2S7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

8128:LOC100711777
gene id: 8128:LOC100711777
uniprot id: I3KI92
names: Subcellular Location Annotation
messages: Nucleus

8128:stx18
gene id: 8128:stx18
uniprot id: I3KTK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.

8128:LOC100712528
gene id: 8128:LOC100712528
uniprot id: I3KD37
names: Similarity
messages: Belongs to the intermediate filament family.

8128:aplp2
gene id: 8128:aplp2
uniprot id: A0A669B5B0
uniprot id: A0A669F4R9
uniprot id: I3J8E9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100693777
gene id: 8128:LOC100693777
uniprot id: I3J8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8128:grn
gene id: 8128:grn
uniprot id: I3KNY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8128:ogfrl1
gene id: 8128:ogfrl1
uniprot id: A0A669DL16
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

8128:LOC100712137
gene id: 8128:LOC100712137
uniprot id: A0A669F410
names: Similarity
messages: Belongs to the cornifelin family.

8128:LOC100707138
gene id: 8128:LOC100707138
uniprot id: I3IZ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

8128:LOC100707943
gene id: 8128:LOC100707943
uniprot id: A0A669EM83
uniprot id: I3KBS2
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8128:LOC100704669
gene id: 8128:LOC100704669
uniprot id: A0A669DEZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

8128:crybb1
gene id: 8128:crybb1
uniprot id: I3JZQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

8128:srp9
gene id: 8128:srp9
uniprot id: A0A669F103
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

8128:LOC100694335
gene id: 8128:LOC100694335
uniprot id: I3KRG0
names: Subcellular Location Annotation
messages: Membrane

8128:arf1
gene id: 8128:arf1
uniprot id: I3JSS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8128:LOC100695354
gene id: 8128:LOC100695354
uniprot id: I3KZB8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100706730
gene id: 8128:LOC100706730
uniprot id: I3JTG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

8128:LOC100709869
gene id: 8128:LOC100709869
uniprot id: A0A669AZ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8128:hyi
gene id: 8128:hyi
uniprot id: I3JJX4
names: Function
names: Similarity
messages: Belongs to the hyi family.
messages: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

8128:mrpl35
gene id: 8128:mrpl35
uniprot id: I3KW67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

8128:LOC100534434
gene id: 8128:LOC100534434
uniprot id: A0A669FBS5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC109202667
gene id: 8128:LOC109202667
uniprot id: A0A669BT06
uniprot id: I3J427
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

8128:LOC100699797
gene id: 8128:LOC100699797
uniprot id: I3KUJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

8128:xrn1
gene id: 8128:xrn1
uniprot id: A0A669BQH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm

8128:lg16h3orf70
gene id: 8128:lg16h3orf70
uniprot id: A0A669D3W1
names: Similarity
messages: Belongs to the UPF0524 family.

8128:fbxl5
gene id: 8128:fbxl5
uniprot id: I3J4U0
names: Subcellular Location Annotation
messages: perinuclear region

8128:LOC100710560
gene id: 8128:LOC100710560
uniprot id: I3JUQ3
uniprot id: I3JUQ4
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

8128:pigp
gene id: 8128:pigp
uniprot id: A0A669C7R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

8128:LOC100689806
gene id: 8128:LOC100689806
uniprot id: A0A669EI69
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8128:mb21d2
gene id: 8128:mb21d2
uniprot id: I3IY24
names: Similarity
messages: Belongs to the mab-21 family.

8128:LOC100689876
gene id: 8128:LOC100689876
uniprot id: I3KJK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100706309
gene id: 8128:LOC100706309
uniprot id: A0A669E2E2
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

8128:ntf3
gene id: 8128:ntf3
uniprot id: A0A669D054
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

8128:LOC100699552
gene id: 8128:LOC100699552
uniprot id: I3IWT1
names: Similarity
messages: Belongs to the phospholipase D family.

8128:LOC100702954
gene id: 8128:LOC100702954
uniprot id: I3KVY5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:hint3
gene id: 8128:hint3
uniprot id: A0A669CMI9
names: Similarity
messages: Belongs to the HINT family.

8128:LOC100705157
gene id: 8128:LOC100705157
uniprot id: A0A075FJN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

8128:LOC100711132
gene id: 8128:LOC100711132
uniprot id: A0A669AXD6
names: Subcellular Location Annotation
messages: nucleolus

8128:LOC100700272
gene id: 8128:LOC100700272
uniprot id: A0A669CDS0
names: Subcellular Location Annotation
messages: Membrane

8128:dut
gene id: 8128:dut
uniprot id: I3K6Q1
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

8128:gprc5a
gene id: 8128:gprc5a
uniprot id: I3JNP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:rps26
gene id: 8128:rps26
uniprot id: I3KSA7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

8128:LOC102075498
gene id: 8128:LOC102075498
uniprot id: A0A669CJP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC100700261
gene id: 8128:LOC100700261
uniprot id: I3K486
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:hdac9
gene id: 8128:hdac9
uniprot id: I3J443
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus

8128:strn4
gene id: 8128:strn4
uniprot id: I3JFD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

8128:c5
gene id: 8128:c5
uniprot id: I3IW28
names: Subcellular Location Annotation
messages: Secreted

8128:LOC100709289
gene id: 8128:LOC100709289
uniprot id: A0A669D6Y9
uniprot id: I3KVA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

8128:LOC100697350
gene id: 8128:LOC100697350
uniprot id: I3KZZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8128:alg6
gene id: 8128:alg6
uniprot id: I3JQF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100706153
gene id: 8128:LOC100706153
uniprot id: I3IUR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC109204650
gene id: 8128:LOC109204650
uniprot id: A0A669CY97
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8128:LOC100701200
gene id: 8128:LOC100701200
uniprot id: I3JCS0
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

8128:zdhhc15
gene id: 8128:zdhhc15
uniprot id: A0A669BSR2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC100700735
gene id: 8128:LOC100700735
uniprot id: A0A669ERI6
names: Similarity
messages: Belongs to the PPP phosphatase family.

8128:LOC100692423
gene id: 8128:LOC100692423
uniprot id: I3KYB7
names: Subcellular Location Annotation
messages: Membrane

8128:zdhhc24
gene id: 8128:zdhhc24
uniprot id: A0A669DQB2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC100707403
gene id: 8128:LOC100707403
uniprot id: I3J7Y8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8128:LOC100695466
gene id: 8128:LOC100695466
uniprot id: A0A669B3J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

8128:LOC100706520
gene id: 8128:LOC100706520
uniprot id: I3JJF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

8128:bbs5
gene id: 8128:bbs5
uniprot id: I3JQB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: centriolar satellite
messages: cilium membrane

8128:LOC100690617
gene id: 8128:LOC100690617
uniprot id: I3L032
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100704073
gene id: 8128:LOC100704073
uniprot id: A0A669BZE9
uniprot id: I3J461
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

8128:nrxn1
gene id: 8128:nrxn1
uniprot id: A0A669BXH4
uniprot id: A0A669CYJ8
uniprot id: A0A669D8L8
uniprot id: A0A669EDX6
uniprot id: A0A669EHU8
uniprot id: A0A669FC76
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100705237
gene id: 8128:LOC100705237
uniprot id: A0A669DWN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

8128:LOC100696317
gene id: 8128:LOC100696317
uniprot id: I3JSV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:prim1
gene id: 8128:prim1
uniprot id: I3KK59
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

8128:wnt7b
gene id: 8128:wnt7b
uniprot id: I3JQH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8128:wrb
gene id: 8128:wrb
uniprot id: I3JDC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100702754
gene id: 8128:LOC100702754
uniprot id: A0A669DXF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

8128:tmem178a
gene id: 8128:tmem178a
uniprot id: I3KV19
names: Similarity
messages: Belongs to the TMEM178 family.

8128:slc1a5
gene id: 8128:slc1a5
uniprot id: I3JFC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8128:LOC100705310
gene id: 8128:LOC100705310
uniprot id: I3JE28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

8128:cdc45
gene id: 8128:cdc45
uniprot id: I3KAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

8128:iglon5
gene id: 8128:iglon5
uniprot id: A0A669EHX1
names: Subcellular Location Annotation
messages: Membrane

8128:pnn
gene id: 8128:pnn
uniprot id: A0A669CZ01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

8128:ppp2r5e
gene id: 8128:ppp2r5e
uniprot id: A0A669D3M8
uniprot id: A0A669E7F7
uniprot id: I3J006
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8128:LOC100701802
gene id: 8128:LOC100701802
uniprot id: I3KCA8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:lrp5
gene id: 8128:lrp5
uniprot id: A0A669C726
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:g6pc
gene id: 8128:g6pc
uniprot id: I3KPG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8128:cystm1
gene id: 8128:cystm1
uniprot id: A0A669BQS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYSTM1 family.
messages: Membrane

8128:LOC100699062
gene id: 8128:LOC100699062
uniprot id: I3KE10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

8128:LOC100703444
gene id: 8128:LOC100703444
uniprot id: I3KGC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:acbd7
gene id: 8128:acbd7
uniprot id: I3JFT2
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8128:LOC100699659
gene id: 8128:LOC100699659
uniprot id: A0A669CG08
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

8128:ccser2
gene id: 8128:ccser2
uniprot id: A0A669D7I0
uniprot id: A0A669E8W3
names: Similarity
messages: Belongs to the CCSER family.

8128:LOC100700532
gene id: 8128:LOC100700532
uniprot id: I3KZ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

8128:LOC100712494
gene id: 8128:LOC100712494
uniprot id: A0A669BUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

8128:snx5
gene id: 8128:snx5
uniprot id: I3JUP7
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

8128:LOC100704449
gene id: 8128:LOC100704449
uniprot id: I3J1T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

8128:dpys
gene id: 8128:dpys
uniprot id: A0A669DRM8
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

8128:magoh
gene id: 8128:magoh
uniprot id: I3KSV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

8128:LOC100696252
gene id: 8128:LOC100696252
uniprot id: I3JBQ2
names: Subcellular Location Annotation
messages: Membrane

8128:ranbp10
gene id: 8128:ranbp10
uniprot id: A0A669DM06
names: Similarity
messages: Belongs to the RANBP9/10 family.

8128:LOC100700979
gene id: 8128:LOC100700979
uniprot id: I3K574
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8128:fam136a
gene id: 8128:fam136a
uniprot id: I3J6N3
names: Similarity
messages: Belongs to the FAM136 family.

8128:nsg2
gene id: 8128:nsg2
uniprot id: A0A669DHQ1
names: Similarity
messages: Belongs to the NSG family.

8128:LOC100700264
gene id: 8128:LOC100700264
uniprot id: I3K1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:LOC100707634
gene id: 8128:LOC100707634
uniprot id: A0A669D7E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8128:LOC100695211
gene id: 8128:LOC100695211
uniprot id: I3KT92
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

8128:LOC109204099
gene id: 8128:LOC109204099
uniprot id: A0A669EDM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8128:nodal
gene id: 8128:nodal
uniprot id: I3KGQ3
names: Similarity
messages: Belongs to the TGF-beta family.

8128:tspan15
gene id: 8128:tspan15
uniprot id: I3KK37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:phf8
gene id: 8128:phf8
uniprot id: I3K1X4
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8128:antxr2
gene id: 8128:antxr2
uniprot id: A0A669BMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

8128:LOC100700535
gene id: 8128:LOC100700535
uniprot id: A0A669D3E7
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8128:bsx
gene id: 8128:bsx
uniprot id: A0A669ESL3
names: Subcellular Location Annotation
messages: Nucleus

8128:ruvbl1
gene id: 8128:ruvbl1
uniprot id: I3KS74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

8128:LOC100694525
gene id: 8128:LOC100694525
uniprot id: A0A669BCN8
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

8128:adamts18
gene id: 8128:adamts18
uniprot id: I3J506
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:cap1
gene id: 8128:cap1
uniprot id: A0A669C2I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

8128:LOC100534452
gene id: 8128:LOC100534452
uniprot id: A0A0B4J1Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

8128:cfdp1
gene id: 8128:cfdp1
uniprot id: I3J8D7
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

8128:slc2a11
gene id: 8128:slc2a11
uniprot id: A0A669DQ53
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8128:LOC100706964
gene id: 8128:LOC100706964
uniprot id: I3JGH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

8128:LOC100699090
gene id: 8128:LOC100699090
uniprot id: A0A669CMJ4
uniprot id: I3JFU5
names: Subcellular Location Annotation
messages: Nucleus

8128:zhx2
gene id: 8128:zhx2
uniprot id: I3JJZ8
uniprot id: I3JJZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8128:LOC100712401
gene id: 8128:LOC100712401
uniprot id: A0A669BTW8
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8128:LOC100690520
gene id: 8128:LOC100690520
uniprot id: I3JFX6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8128:apmap
gene id: 8128:apmap
uniprot id: I3JJA2
names: Similarity
messages: Belongs to the strictosidine synthase family.

8128:trdmt1
gene id: 8128:trdmt1
uniprot id: A0A669C5N2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

8128:eloc
gene id: 8128:eloc
uniprot id: A0A669CWR5
names: Similarity
messages: Belongs to the SKP1 family.

8128:LOC100694437
gene id: 8128:LOC100694437
uniprot id: A0A669F2A1
names: Similarity
messages: Belongs to the NifU family.

8128:fam207a
gene id: 8128:fam207a
uniprot id: A0A669F229
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

8128:LOC100691068
gene id: 8128:LOC100691068
uniprot id: I3JUI6
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:pex13
gene id: 8128:pex13
uniprot id: A0A669CCN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

8128:LOC100707894
gene id: 8128:LOC100707894
uniprot id: A0A669F1D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

8128:LOC100690818
gene id: 8128:LOC100690818
uniprot id: A0A669DSK4
names: Similarity
messages: Belongs to the cystatin family.

8128:stac3
gene id: 8128:stac3
uniprot id: I3J0T2
names: Subcellular Location Annotation
messages: sarcolemma

8128:nek7
gene id: 8128:nek7
uniprot id: A0A669DW94
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:cask
gene id: 8128:cask
uniprot id: A0A669CT94
names: Similarity
messages: Belongs to the MAGUK family.

8128:LOC100698519
gene id: 8128:LOC100698519
uniprot id: A0A669DSE4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100697048
gene id: 8128:LOC100697048
uniprot id: A0A669EQQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8128:LOC100700804
gene id: 8128:LOC100700804
uniprot id: I3IXG5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8128:LOC100701529
gene id: 8128:LOC100701529
uniprot id: A0A669DIF5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

8128:slc16a10
gene id: 8128:slc16a10
uniprot id: I3JZN1
names: Subcellular Location Annotation
messages: Membrane

8128:st3gal4
gene id: 8128:st3gal4
uniprot id: A0A669BV46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:amigo3
gene id: 8128:amigo3
uniprot id: I3KY24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

8128:LOC100702273
gene id: 8128:LOC100702273
uniprot id: A0A669DGN7
names: Similarity
messages: Belongs to the dynein intermediate chain family.

8128:epha5
gene id: 8128:epha5
uniprot id: A0A669BTY5
uniprot id: A0A669EKK7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100691977
gene id: 8128:LOC100691977
uniprot id: A0A669B921
uniprot id: A0A669D5X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

8128:LOC100694290
gene id: 8128:LOC100694290
uniprot id: A0A669B6S0
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

8128:riox2
gene id: 8128:riox2
uniprot id: I3JMC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
messages: nucleolus

8128:ap3s2
gene id: 8128:ap3s2
uniprot id: A0A669E7N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

8128:taf5l
gene id: 8128:taf5l
uniprot id: A0A669DMR7
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

8128:slc17a5
gene id: 8128:slc17a5
uniprot id: A0A669EZF5
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690964
gene id: 8128:LOC100690964
uniprot id: I3K0C7
names: Similarity
messages: Belongs to the TACO1 family.

8128:rack1
gene id: 8128:rack1
uniprot id: O42249
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.
messages: Cytoplasm
messages: Involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Required for VANGL2 membrane localization, inhibits Wnt signaling and regulates cellular polarization and oriented cell division during gastrulation (By similarity).

8128:LOC100696145
gene id: 8128:LOC100696145
uniprot id: I3JUP3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: dendrite

8128:pgm2l1
gene id: 8128:pgm2l1
uniprot id: A0A669CUP7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8128:LOC100691637
gene id: 8128:LOC100691637
uniprot id: I3K858
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

8128:LOC100693406
gene id: 8128:LOC100693406
uniprot id: A0A669ETF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

8128:LOC100699997
gene id: 8128:LOC100699997
uniprot id: I3KGG4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:rock2
gene id: 8128:rock2
uniprot id: A0A669BS19
uniprot id: A0A669E0E2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: Homodimer.
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
messages: centrosome

8128:LOC100691161
gene id: 8128:LOC100691161
uniprot id: I3JH10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

8128:rabep1
gene id: 8128:rabep1
uniprot id: A0A669B152
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

8128:LOC100534423
gene id: 8128:LOC100534423
uniprot id: I3J4C5
names: Subcellular Location Annotation
messages: Nucleus

8128:dck
gene id: 8128:dck
uniprot id: I3JYU0
names: Similarity
messages: Belongs to the DCK/DGK family.

8128:ftsj3
gene id: 8128:ftsj3
uniprot id: I3IZN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

8128:pptc7
gene id: 8128:pptc7
uniprot id: I3KG56
names: Similarity
messages: Belongs to the PP2C family.

8128:LOC100704314
gene id: 8128:LOC100704314
uniprot id: A0A669CUM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8128:LOC100701705
gene id: 8128:LOC100701705
uniprot id: I3K025
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

8128:dedd2
gene id: 8128:dedd2
uniprot id: A0A669B1K3
names: Subcellular Location Annotation
messages: nucleolus

8128:LOC100701067
gene id: 8128:LOC100701067
uniprot id: I3JER9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100707237
gene id: 8128:LOC100707237
uniprot id: I3JMT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8128:gatb
gene id: 8128:gatb
uniprot id: I3JUV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

8128:aox1
gene id: 8128:aox1
uniprot id: M1ZML5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Peroxisome

8128:LOC100697588
gene id: 8128:LOC100697588
uniprot id: A0A669C2L0
uniprot id: I3KG21
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100709259
gene id: 8128:LOC100709259
uniprot id: I3JCT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

8128:srrt
gene id: 8128:srrt
uniprot id: I3J900
names: Similarity
messages: Belongs to the ARS2 family.

8128:LOC100703615
gene id: 8128:LOC100703615
uniprot id: A0A669CCT8
names: Subcellular Location Annotation
messages: Nucleus

8128:ppp1r14c
gene id: 8128:ppp1r14c
uniprot id: I3IVJ1
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8128:LOC100693017
gene id: 8128:LOC100693017
uniprot id: A0A669BY52
names: Similarity
messages: Belongs to the TGF-beta family.

8128:eif3i
gene id: 8128:eif3i
uniprot id: A0A669CEE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8128:LOC100699911
gene id: 8128:LOC100699911
uniprot id: I3JDK5
names: Similarity
messages: Belongs to the RNase T2 family.

8128:LOC100701199
gene id: 8128:LOC100701199
uniprot id: I3JD60
names: Similarity
messages: Belongs to the SNF7 family.

8128:LOC100710636
gene id: 8128:LOC100710636
uniprot id: I3J898
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100712049
gene id: 8128:LOC100712049
uniprot id: I3KKF8
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8128:cisd2
gene id: 8128:cisd2
uniprot id: A0A669CM22
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize becn1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

8128:LOC100702166
gene id: 8128:LOC100702166
uniprot id: I3JSZ0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100690375
gene id: 8128:LOC100690375
uniprot id: I3JGA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8128:hoxd3
gene id: 8128:hoxd3
uniprot id: I3JPN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8128:tmem199
gene id: 8128:tmem199
uniprot id: A0A669E864
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC102080671
gene id: 8128:LOC102080671
uniprot id: A0A669DAX2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100700828
gene id: 8128:LOC100700828
uniprot id: I3K7I6
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100701297
gene id: 8128:LOC100701297
uniprot id: A0A669C565
names: Subcellular Location Annotation
messages: Nucleus

8128:pde1b
gene id: 8128:pde1b
uniprot id: I3JCG8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC100705613
gene id: 8128:LOC100705613
uniprot id: I3KFF1
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:fam120c
gene id: 8128:fam120c
uniprot id: A0A669B0P6
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

8128:phb
gene id: 8128:phb
uniprot id: I3IX27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

8128:zfhx3
gene id: 8128:zfhx3
uniprot id: A0A669DMI0
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100694113
gene id: 8128:LOC100694113
uniprot id: I3JN63
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:fam53b
gene id: 8128:fam53b
uniprot id: I3KGD6
names: Similarity
messages: Belongs to the FAM53 family.

8128:sh2b2
gene id: 8128:sh2b2
uniprot id: I3J7E1
names: Similarity
messages: Belongs to the SH2B adapter family.

8128:LOC100693478
gene id: 8128:LOC100693478
uniprot id: A0A669D3E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8128:LOC102078041
gene id: 8128:LOC102078041
uniprot id: I3KYA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

8128:heg1
gene id: 8128:heg1
uniprot id: I3J8Y7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:sepsecs
gene id: 8128:sepsecs
uniprot id: A0A669BGV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

8128:lrp4
gene id: 8128:lrp4
uniprot id: I3JJI4
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100696456
gene id: 8128:LOC100696456
uniprot id: I3KQ48
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:LOC100706607
gene id: 8128:LOC100706607
uniprot id: A0A669BZJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8128:LOC100709246
gene id: 8128:LOC100709246
uniprot id: A0A669BND1
uniprot id: A0A669DV09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

8128:lamtor3
gene id: 8128:lamtor3
uniprot id: A0A669F3R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR3 family.
messages: Endosome membrane
messages: Late endosome membrane

8128:rbck1
gene id: 8128:rbck1
uniprot id: I3JI92
names: Similarity
messages: Belongs to the RBR family.

8128:LOC100691663
gene id: 8128:LOC100691663
uniprot id: I3JIH8
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8128:LOC100534419
gene id: 8128:LOC100534419
uniprot id: A7BI99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:LOC100702436
gene id: 8128:LOC100702436
uniprot id: A0A669E1U8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100700051
gene id: 8128:LOC100700051
uniprot id: A0A669BFD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

8128:mttp
gene id: 8128:mttp
uniprot id: I3KAW4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:tmcc1
gene id: 8128:tmcc1
uniprot id: A0A669CVM5
uniprot id: A0A669EZC3
uniprot id: A0A669F5F3
uniprot id: I3KKT5
names: Similarity
messages: Belongs to the TEX28 family.

8128:LOC100703610
gene id: 8128:LOC100703610
uniprot id: A0A669BYX2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100709332
gene id: 8128:LOC100709332
uniprot id: I3J2E3
uniprot id: I3J2E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

8128:LOC100703461
gene id: 8128:LOC100703461
uniprot id: I3KW35
names: Similarity
messages: Belongs to the YY transcription factor family.

8128:LOC100692331
gene id: 8128:LOC100692331
uniprot id: A0A669C6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8128:hmx2
gene id: 8128:hmx2
uniprot id: I3IVN6
names: Subcellular Location Annotation
messages: Nucleus

8128:calcrl
gene id: 8128:calcrl
uniprot id: I3JAC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP). Receptor specificity may be modulated by accessory proteins. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

8128:LOC100702785
gene id: 8128:LOC100702785
uniprot id: I3J7S2
names: Similarity
messages: Belongs to the FAM168 family.

8128:LOC100710561
gene id: 8128:LOC100710561
uniprot id: I3KT06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

8128:anp32a
gene id: 8128:anp32a
uniprot id: A0A669BFJ9
names: Similarity
messages: Belongs to the ANP32 family.

8128:LOC109194741
gene id: 8128:LOC109194741
uniprot id: A0A669EEW0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:prkcq
gene id: 8128:prkcq
uniprot id: I3KN71
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

8128:LOC100696716
gene id: 8128:LOC100696716
uniprot id: A0A669EFA4
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

8128:LOC100711386
gene id: 8128:LOC100711386
uniprot id: A0A669DBW1
uniprot id: I3JNV6
names: Similarity
messages: Belongs to the JAKMIP family.

8128:emc3
gene id: 8128:emc3
uniprot id: A0A669DF25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

8128:fam160a2
gene id: 8128:fam160a2
uniprot id: I3KK96
names: Similarity
messages: Belongs to the FHIP family.

8128:LOC100711584
gene id: 8128:LOC100711584
uniprot id: I3JL52
names: Similarity
messages: Belongs to the myozenin family.

8128:LOC100695228
gene id: 8128:LOC100695228
uniprot id: A0A669CXR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:nrp2
gene id: 8128:nrp2
uniprot id: A0A669EMI6
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100699992
gene id: 8128:LOC100699992
uniprot id: I3K639
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

8128:dpy19l1
gene id: 8128:dpy19l1
uniprot id: I3JHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

8128:LOC100691147
gene id: 8128:LOC100691147
uniprot id: I3K937
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:lin7a
gene id: 8128:lin7a
uniprot id: A0A669EKB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

8128:LOC100709904
gene id: 8128:LOC100709904
uniprot id: A0A669BGM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

8128:ano3
gene id: 8128:ano3
uniprot id: I3JNI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

8128:LOC100707400
gene id: 8128:LOC100707400
uniprot id: A0A669AXT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

8128:LOC100697225
gene id: 8128:LOC100697225
uniprot id: I3K4P3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:crh
gene id: 8128:crh
uniprot id: I3KX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

8128:cc2d1a
gene id: 8128:cc2d1a
uniprot id: I3KML5
names: Similarity
messages: Belongs to the CC2D1 family.

8128:camsap1
gene id: 8128:camsap1
uniprot id: A0A669D572
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8128:ogn
gene id: 8128:ogn
uniprot id: I3IVI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
messages: extracellular matrix

8128:LOC100708195
gene id: 8128:LOC100708195
uniprot id: I3KXT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:rabac1
gene id: 8128:rabac1
uniprot id: I3K5T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8128:LOC102078595
gene id: 8128:LOC102078595
uniprot id: A0A669B254
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

8128:LOC100712040
gene id: 8128:LOC100712040
uniprot id: I3K8D8
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8128:LOC102077463
gene id: 8128:LOC102077463
uniprot id: A0A669EE19
names: Subcellular Location Annotation
messages: Membrane

8128:LOC109204285
gene id: 8128:LOC109204285
uniprot id: A0A669D429
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8128:hars
gene id: 8128:hars
uniprot id: A0A669C0W9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

8128:eva1a
gene id: 8128:eva1a
uniprot id: I3KBQ0
names: Similarity
messages: Belongs to the EVA1 family.

8128:bckdha
gene id: 8128:bckdha
uniprot id: I3J891
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BCKDHA family.
messages: Heterotetramer of alpha and beta chains.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

8128:LOC106096419
gene id: 8128:LOC106096419
uniprot id: A0A669CWQ1
names: Subcellular Location Annotation
messages: Membrane

8128:sprn
gene id: 8128:sprn
uniprot id: I3L067
names: Similarity
messages: Belongs to the SPRN family.

8128:tmem182
gene id: 8128:tmem182
uniprot id: A0A669F7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

8128:LOC100701790
gene id: 8128:LOC100701790
uniprot id: A0A669DTF5
names: Subcellular Location Annotation
messages: Nucleus

8128:capn15
gene id: 8128:capn15
uniprot id: I3KVT0
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:fam3a
gene id: 8128:fam3a
uniprot id: I3K1W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

8128:LOC100690783
gene id: 8128:LOC100690783
uniprot id: A0A669DVN8
uniprot id: A0A669EUA3
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

8128:atp11c
gene id: 8128:atp11c
uniprot id: A0A669BHK2
uniprot id: A0A669E1U5
uniprot id: A0A669F0M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8128:LOC100693659
gene id: 8128:LOC100693659
uniprot id: I3JV45
names: Similarity
messages: Belongs to the FAM102 family.

8128:ndfip1
gene id: 8128:ndfip1
uniprot id: A0A669CAN0
uniprot id: A0A669F5C2
names: Subcellular Location Annotation
messages: Membrane

8128:pif1
gene id: 8128:pif1
uniprot id: I3JWJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
messages: Mitochondrion
messages: Monomer.
messages: Nucleus

8128:LOC100708900
gene id: 8128:LOC100708900
uniprot id: A0A669CM67
names: Similarity
messages: Belongs to the peptidase C48 family.

8128:ckap5
gene id: 8128:ckap5
uniprot id: I3K4F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOG/XMAP215 family.
messages: kinetochore

8128:dbndd1
gene id: 8128:dbndd1
uniprot id: I3JE11
names: Similarity
messages: Belongs to the dysbindin family.

8128:gipc1
gene id: 8128:gipc1
uniprot id: I3J0R3
names: Similarity
messages: Belongs to the GIPC family.

8128:slc12a4
gene id: 8128:slc12a4
uniprot id: A0A669BAA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8128:LOC100693041
gene id: 8128:LOC100693041
uniprot id: I3JS71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

8128:LOC100702990
gene id: 8128:LOC100702990
uniprot id: I3J4X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

8128:cd36
gene id: 8128:cd36
uniprot id: A0A669EWU9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the CD36 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: Membrane raft

8128:LOC100700540
gene id: 8128:LOC100700540
uniprot id: A0A669EAI3
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8128:LOC102078032
gene id: 8128:LOC102078032
uniprot id: I3K6S9
names: Similarity
messages: Belongs to the RAMP family.

8128:LOC102078475
gene id: 8128:LOC102078475
uniprot id: A0A669BB10
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:prdm6
gene id: 8128:prdm6
uniprot id: I3K8D0
names: Subcellular Location Annotation
messages: Nucleus

8128:atg4d
gene id: 8128:atg4d
uniprot id: A0A669F5N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8128:LOC102079789
gene id: 8128:LOC102079789
uniprot id: I3JPE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane

8128:tfip11
gene id: 8128:tfip11
uniprot id: I3K7S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFP11/STIP family.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.
messages: Nucleus

8128:LOC100705560
gene id: 8128:LOC100705560
uniprot id: I3JZL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

8128:traf3
gene id: 8128:traf3
uniprot id: I3K142
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8128:LOC100691882
gene id: 8128:LOC100691882
uniprot id: A0A669CNI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm

8128:LOC100702982
gene id: 8128:LOC100702982
uniprot id: A0A669DHH6
uniprot id: A0A669E115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8128:grk6
gene id: 8128:grk6
uniprot id: A0A669CP56
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8128:hacl1
gene id: 8128:hacl1
uniprot id: A0A669D2V1
names: Similarity
messages: Belongs to the TPP enzyme family.

8128:dcp1a
gene id: 8128:dcp1a
uniprot id: I3J0I3
names: Similarity
messages: Belongs to the DCP1 family.

8128:dcaf11
gene id: 8128:dcaf11
uniprot id: I3JMX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat LEC14B family.
messages: Interacts with DDB1 and CUL4A.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

8128:LOC109199766
gene id: 8128:LOC109199766
uniprot id: A0A669DKS7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100708075
gene id: 8128:LOC100708075
uniprot id: I3K0C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC100710503
gene id: 8128:LOC100710503
uniprot id: I3KNM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:LOC100693448
gene id: 8128:LOC100693448
uniprot id: I3KZA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:LOC100699429
gene id: 8128:LOC100699429
uniprot id: A0A669DBW0
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

8128:romo1
gene id: 8128:romo1
uniprot id: A0A669DGF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

8128:LOC102082086
gene id: 8128:LOC102082086
uniprot id: A0A669B6L7
names: Similarity
messages: Belongs to the ARTD/PARP family.

8128:lrrc4
gene id: 8128:lrrc4
uniprot id: I3KYS0
names: Subcellular Location Annotation
messages: Membrane

8128:gtf3c5
gene id: 8128:gtf3c5
uniprot id: I3K5G8
names: Subcellular Location Annotation
messages: Nucleus

8128:fam114a2
gene id: 8128:fam114a2
uniprot id: I3KHX0
names: Similarity
messages: Belongs to the FAM114 family.

8128:LOC100704302
gene id: 8128:LOC100704302
uniprot id: I3JKB3
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

8128:LOC100698829
gene id: 8128:LOC100698829
uniprot id: I3KS86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC109204181
gene id: 8128:LOC109204181
uniprot id: A0A669DRM2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:frzb
gene id: 8128:frzb
uniprot id: A0A669CNZ4
uniprot id: I3KH54
names: Caution
names: Function
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

8128:chac1
gene id: 8128:chac1
uniprot id: A0A669B1P0
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

8128:cyp11b
gene id: 8128:cyp11b
uniprot id: A0A669D5X1
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100702008
gene id: 8128:LOC100702008
uniprot id: I3JAU9
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8128:LOC100705611
gene id: 8128:LOC100705611
uniprot id: A0A669B5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane

8128:LOC100701831
gene id: 8128:LOC100701831
uniprot id: A0A669DXD5
uniprot id: I3KG39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8128:nmnat2
gene id: 8128:nmnat2
uniprot id: I3IUR7
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

8128:mtus1
gene id: 8128:mtus1
uniprot id: A0A669C7W8
uniprot id: I3KM85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTUS1 family.
messages: Nucleus

8128:LOC100692622
gene id: 8128:LOC100692622
uniprot id: I3JCB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8128:LOC100710690
gene id: 8128:LOC100710690
uniprot id: I3JQQ5
names: Similarity
messages: Belongs to the HPF1 family.

8128:ckb
gene id: 8128:ckb
uniprot id: I3K3E7
uniprot id: I3K3E8
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8128:LOC100534441
gene id: 8128:LOC100534441
uniprot id: B7SU42
uniprot id: I3KY06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8128:fat1
gene id: 8128:fat1
uniprot id: A0A669DSQ2
uniprot id: I3JV89
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100706251
gene id: 8128:LOC100706251
uniprot id: I3KUY7
names: Similarity
messages: Belongs to the TOM1 family.

8128:LOC100694039
gene id: 8128:LOC100694039
uniprot id: A0A669F6E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane

8128:pole
gene id: 8128:pole
uniprot id: I3K7B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

8128:ankrd34a
gene id: 8128:ankrd34a
uniprot id: I3KYR0
names: Similarity
messages: Belongs to the ANKRD34 family.

8128:LOC100689898
gene id: 8128:LOC100689898
uniprot id: I3KU66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Membrane

8128:cnot8
gene id: 8128:cnot8
uniprot id: A0A669B0D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

8128:bcap31
gene id: 8128:bcap31
uniprot id: I3KB97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

8128:fam192a
gene id: 8128:fam192a
uniprot id: I3JYX9
names: Subcellular Location Annotation
messages: Nucleus

8128:pkp3
gene id: 8128:pkp3
uniprot id: A0A669DXZ2
uniprot id: I3JNG0
names: Similarity
messages: Belongs to the beta-catenin family.

8128:LOC100694808
gene id: 8128:LOC100694808
uniprot id: I3K013
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

8128:LOC100700586
gene id: 8128:LOC100700586
uniprot id: I3KW85
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100690407
gene id: 8128:LOC100690407
uniprot id: A0A669BX89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC102081895
gene id: 8128:LOC102081895
uniprot id: I3KYY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8128:agpat5
gene id: 8128:agpat5
uniprot id: I3JTF4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:LOC100697998
gene id: 8128:LOC100697998
uniprot id: I3IUD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8128:sema3a
gene id: 8128:sema3a
uniprot id: A0A669AWV4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:mettl6
gene id: 8128:mettl6
uniprot id: A0A669B029
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

8128:LOC109204782
gene id: 8128:LOC109204782
uniprot id: A0A669CHV2
names: Subcellular Location Annotation
messages: Membrane

8128:pld4
gene id: 8128:pld4
uniprot id: A0A669CM65
names: Similarity
messages: Belongs to the phospholipase D family.

8128:LOC100706253
gene id: 8128:LOC100706253
uniprot id: I3KGR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

8128:bloc1s5
gene id: 8128:bloc1s5
uniprot id: I3KB14
names: Similarity
messages: Belongs to the BLOC1S5 family.

8128:LOC102077314
gene id: 8128:LOC102077314
uniprot id: I3KKC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:nkiras1
gene id: 8128:nkiras1
uniprot id: A0A669BAN6
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

8128:LOC100697055
gene id: 8128:LOC100697055
uniprot id: A0A669DC60
uniprot id: A0A669DP57
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: lamellipodium

8128:npepl1
gene id: 8128:npepl1
uniprot id: A0A669DZ18
names: Similarity
messages: Belongs to the peptidase M17 family.

8128:pdrg1
gene id: 8128:pdrg1
uniprot id: A0A669CYQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

8128:LOC100707011
gene id: 8128:LOC100707011
uniprot id: I3JU43
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100704161
gene id: 8128:LOC100704161
uniprot id: I3K768
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPACA4/bouncer family.
messages: Cell membrane
messages: Membrane

8128:slc17a6
gene id: 8128:slc17a6
uniprot id: I3JNI1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100707074
gene id: 8128:LOC100707074
uniprot id: A0A669ET61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8128:rybp
gene id: 8128:rybp
uniprot id: I3KWN8
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100696343
gene id: 8128:LOC100696343
uniprot id: A0A669CHW1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100710458
gene id: 8128:LOC100710458
uniprot id: A0A669E1C0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

8128:LOC100711565
gene id: 8128:LOC100711565
uniprot id: A0A669BGT7
names: Similarity
messages: Belongs to the DCP1 family.

8128:tatdn1
gene id: 8128:tatdn1
uniprot id: A0A669EJY8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

8128:gli3
gene id: 8128:gli3
uniprot id: I3JGE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus

8128:impad1
gene id: 8128:impad1
uniprot id: I3KIL3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8128:lclat1
gene id: 8128:lclat1
uniprot id: I3IYM7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:phf5a
gene id: 8128:phf5a
uniprot id: A0A669D3P6
names: Similarity
messages: Belongs to the PHF5 family.

8128:LOC100703562
gene id: 8128:LOC100703562
uniprot id: I3KTD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:fam208a
gene id: 8128:fam208a
uniprot id: I3J995
names: Similarity
messages: Belongs to the TASOR family.

8128:LOC100698703
gene id: 8128:LOC100698703
uniprot id: A0A669B132
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:LOC100534515
gene id: 8128:LOC100534515
uniprot id: Q9YH32
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer. Can form a heterodimer with ER-alpha (By similarity).
messages: Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Nucleus

8128:hikeshi
gene id: 8128:hikeshi
uniprot id: I3KYD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

8128:LOC100708886
gene id: 8128:LOC100708886
uniprot id: A0A669BAQ7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:LOC100703084
gene id: 8128:LOC100703084
uniprot id: A0A669CRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

8128:s100z
gene id: 8128:s100z
uniprot id: A0A669E9S3
names: Similarity
messages: Belongs to the S-100 family.

8128:nck2
gene id: 8128:nck2
uniprot id: I3K9S8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

8128:LOC100710567
gene id: 8128:LOC100710567
uniprot id: A0A669B1F9
names: Similarity
messages: Belongs to the heme oxygenase family.

8128:LOC100697672
gene id: 8128:LOC100697672
uniprot id: I3KWT5
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

8128:LOC100708189
gene id: 8128:LOC100708189
uniprot id: A0A669E7N5
names: Similarity
messages: Belongs to the PDCD4 family.

8128:taf11
gene id: 8128:taf11
uniprot id: I3KJX7
names: Similarity
messages: Belongs to the TAF11 family.

8128:LOC100704224
gene id: 8128:LOC100704224
uniprot id: A0A669D0A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8128:apoc2
gene id: 8128:apoc2
uniprot id: I7J7S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C2 family.
messages: Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.
messages: Secreted

8128:polr3a
gene id: 8128:polr3a
uniprot id: A0A669E825
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

8128:LOC102081444
gene id: 8128:LOC102081444
uniprot id: I3K3V4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

8128:LOC100706692
gene id: 8128:LOC100706692
uniprot id: A0A669EKN9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:trit1
gene id: 8128:trit1
uniprot id: I3KE38
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

8128:LOC100692640
gene id: 8128:LOC100692640
uniprot id: A0A669EKH3
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8128:mdm1
gene id: 8128:mdm1
uniprot id: I3KNM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM1 family.
messages: Nucleus
messages: centriole

8128:atp5pf
gene id: 8128:atp5pf
uniprot id: A0A669ELQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion inner membrane

8128:LOC100706680
gene id: 8128:LOC100706680
uniprot id: A0A669E5G9
names: Subcellular Location Annotation
messages: Nucleus

8128:hspb1
gene id: 8128:hspb1
uniprot id: I3K4I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

8128:parn
gene id: 8128:parn
uniprot id: I3IUA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Cytoplasm
messages: Nucleus

8128:mcee
gene id: 8128:mcee
uniprot id: I3J4G2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

8128:LOC100711588
gene id: 8128:LOC100711588
uniprot id: A0A669F711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8128:xylb
gene id: 8128:xylb
uniprot id: A0A669DDU7
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

8128:LOC100696823
gene id: 8128:LOC100696823
uniprot id: A0A669EYV1
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

8128:nkd2
gene id: 8128:nkd2
uniprot id: A0A669C5H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8128:LOC100708704
gene id: 8128:LOC100708704
uniprot id: I3KDF8
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

8128:lgmn
gene id: 8128:lgmn
uniprot id: A0A669DA26
names: Similarity
messages: Belongs to the peptidase C13 family.

8128:LOC100692170
gene id: 8128:LOC100692170
uniprot id: A0A669E1A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm

8128:slc30a5
gene id: 8128:slc30a5
uniprot id: I3K4U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Membrane
messages: trans-Golgi network membrane

8128:tbx4
gene id: 8128:tbx4
uniprot id: I3JWA3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:LOC102079550
gene id: 8128:LOC102079550
uniprot id: A0A669BA41
names: Similarity
messages: Belongs to the peptidase S1B family.

8128:LOC100697174
gene id: 8128:LOC100697174
uniprot id: A0A669EQR1
uniprot id: A0A669F2E3
uniprot id: I3IU11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

8128:trmt112
gene id: 8128:trmt112
uniprot id: I3JD29
names: Similarity
messages: Belongs to the TRM112 family.

8128:tmlhe
gene id: 8128:tmlhe
uniprot id: I3J090
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

8128:LOC100709337
gene id: 8128:LOC100709337
uniprot id: A0A669C827
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8128:rps8
gene id: 8128:rps8
uniprot id: A0A669CYT8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

8128:LOC100711848
gene id: 8128:LOC100711848
uniprot id: I3K1X7
names: Similarity
messages: Belongs to the sorting nexin family.

8128:cdc42bpa
gene id: 8128:cdc42bpa
uniprot id: A0A669DHV6
uniprot id: A0A669F1K0
uniprot id: I3IY72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: lamellipodium

8128:marf1
gene id: 8128:marf1
uniprot id: A0A669DEB3
names: Subcellular Location Annotation
messages: Peroxisome

8128:unc119b
gene id: 8128:unc119b
uniprot id: A0A669ENG0
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8128:ddx41
gene id: 8128:ddx41
uniprot id: A0A669EFF5
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

8128:eif4enif1
gene id: 8128:eif4enif1
uniprot id: A0A669ETC2
names: Subcellular Location Annotation
messages: Cytoplasm

8128:snx19
gene id: 8128:snx19
uniprot id: I3KBS3
names: Similarity
messages: Belongs to the sorting nexin family.

8128:LOC100692904
gene id: 8128:LOC100692904
uniprot id: I3JKA6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100697435
gene id: 8128:LOC100697435
uniprot id: A0A669DRK2
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8128:enkur
gene id: 8128:enkur
uniprot id: A0A669CYH8
names: Subcellular Location Annotation
messages: cilium axoneme

8128:mrpl13
gene id: 8128:mrpl13
uniprot id: A0A669BHV0
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

8128:ror1
gene id: 8128:ror1
uniprot id: I3JQD8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100695100
gene id: 8128:LOC100695100
uniprot id: A0A669F7Q0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8128:rbp2
gene id: 8128:rbp2
uniprot id: I3KB88
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8128:tacr3a
gene id: 8128:tacr3a
uniprot id: I3KB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC102078829
gene id: 8128:LOC102078829
uniprot id: I3J7U7
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:nutf2
gene id: 8128:nutf2
uniprot id: I3JYP0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

8128:LOC100694289
gene id: 8128:LOC100694289
uniprot id: I3J637
names: Similarity
messages: Belongs to the taxilin family.

8128:LOC100689943
gene id: 8128:LOC100689943
uniprot id: I3KGW5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

8128:glrx2
gene id: 8128:glrx2
uniprot id: I3JY28
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

8128:LOC100711030
gene id: 8128:LOC100711030
uniprot id: A0A669DXC5
names: Similarity
messages: Belongs to the TAFA family.

8128:LOC100694598
gene id: 8128:LOC100694598
uniprot id: A0A669D8Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

8128:LOC100698833
gene id: 8128:LOC100698833
uniprot id: I3J0M8
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8128:pigl
gene id: 8128:pigl
uniprot id: I3K4U6
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

8128:dlgap3
gene id: 8128:dlgap3
uniprot id: I3JAP1
names: Similarity
messages: Belongs to the SAPAP family.

8128:mecp2
gene id: 8128:mecp2
uniprot id: A0A669B400
names: Subcellular Location Annotation
messages: Nucleus

8128:il17d
gene id: 8128:il17d
uniprot id: I3KF89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

8128:psma5
gene id: 8128:psma5
uniprot id: I3KT68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8128:LOC100698045
gene id: 8128:LOC100698045
uniprot id: A0A669B634
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

8128:LOC109198419
gene id: 8128:LOC109198419
uniprot id: A0A669D1D9
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100694715
gene id: 8128:LOC100694715
uniprot id: A0A669CMG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8128:polr2m
gene id: 8128:polr2m
uniprot id: I3JEM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRINL1 family.
messages: Nucleus

8128:chrdl2
gene id: 8128:chrdl2
uniprot id: I3JCH0
names: Subcellular Location Annotation
messages: Secreted

8128:nagk
gene id: 8128:nagk
uniprot id: A0A669BLQ0
uniprot id: A0A669CY83
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

8128:mettl14
gene id: 8128:mettl14
uniprot id: A0A669BV35
names: Similarity
messages: Belongs to the MT-A70-like family.

8128:LOC109197029
gene id: 8128:LOC109197029
uniprot id: A0A669BD48
uniprot id: A0A669EC09
uniprot id: A0A669EZP2
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:stac
gene id: 8128:stac
uniprot id: I3J6L3
uniprot id: I3J6L4
names: Subcellular Location Annotation
messages: sarcolemma

8128:mfsd1
gene id: 8128:mfsd1
uniprot id: A0A669AWS6
uniprot id: A0A669DSF4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC102080585
gene id: 8128:LOC102080585
uniprot id: I3JT34
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:cse1l
gene id: 8128:cse1l
uniprot id: Q8AY73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPO2/CSE1 family.
messages: Cytoplasm
messages: Export receptor for importin alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm (By similarity). Negatively regulates fluid secretion and plays a role in fluid homeostasis by down-regulating cftr activity (By similarity).
messages: Interacts with cftr.
messages: Nucleus

8128:LOC100695502
gene id: 8128:LOC100695502
uniprot id: I3KUL2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8128:unc119
gene id: 8128:unc119
uniprot id: I3JN60
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8128:LOC100703896
gene id: 8128:LOC100703896
uniprot id: I3J882
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8128:LOC109204162
gene id: 8128:LOC109204162
uniprot id: A0A669D2J7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100700351
gene id: 8128:LOC100700351
uniprot id: I3KTB9
names: Similarity
messages: Belongs to the CAMK2N family.

8128:gabrb2
gene id: 8128:gabrb2
uniprot id: A0A669C6C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100705132
gene id: 8128:LOC100705132
uniprot id: I3KH58
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC100708980
gene id: 8128:LOC100708980
uniprot id: A0A669CCA5
names: Similarity
messages: Belongs to the NAC-beta family.

8128:LOC100697206
gene id: 8128:LOC100697206
uniprot id: I3J4F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8128:LOC100534432
gene id: 8128:LOC100534432
uniprot id: Q8UVJ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:uhrf2
gene id: 8128:uhrf2
uniprot id: I3K980
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100699221
gene id: 8128:LOC100699221
uniprot id: A0A669B2E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

8128:tctex1d2
gene id: 8128:tctex1d2
uniprot id: A0A669DQT5
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8128:ikbkb
gene id: 8128:ikbkb
uniprot id: I3KAB1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:vldlr
gene id: 8128:vldlr
uniprot id: A0A669C3X7
uniprot id: I3K4J3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: clathrin-coated pit

8128:LOC100712136
gene id: 8128:LOC100712136
uniprot id: A0A669CPQ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:myod1
gene id: 8128:myod1
uniprot id: D2XRC0
uniprot id: I3JXI0
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8128:snx21
gene id: 8128:snx21
uniprot id: I3KBP3
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

8128:tmod4
gene id: 8128:tmod4
uniprot id: A0A669DLY7
names: Subcellular Location Annotation
messages: cytoskeleton

8128:LOC100705584
gene id: 8128:LOC100705584
uniprot id: A0A669AX05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

8128:kdelc1
gene id: 8128:kdelc1
uniprot id: I3J987
names: Similarity
messages: Belongs to the KDELC family.

8128:nudt1
gene id: 8128:nudt1
uniprot id: A0A669D9F9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

8128:LOC100707330
gene id: 8128:LOC100707330
uniprot id: A0A669BMU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

8128:npnt
gene id: 8128:npnt
uniprot id: A0A669D3S4
uniprot id: I3KLV1
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC109204552
gene id: 8128:LOC109204552
uniprot id: A0A669CM53
names: Subcellular Location Annotation
messages: extracellular space

8128:gpr180
gene id: 8128:gpr180
uniprot id: I3KDR3
names: Subcellular Location Annotation
messages: Membrane

8128:miga2
gene id: 8128:miga2
uniprot id: I3JK98
names: Similarity
messages: Belongs to the mitoguardin family.

8128:ptger3
gene id: 8128:ptger3
uniprot id: A0A669EF83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:ctnnbip1
gene id: 8128:ctnnbip1
uniprot id: I3J291
names: Similarity
messages: Belongs to the CTNNBIP1 family.

8128:itga1
gene id: 8128:itga1
uniprot id: A0A669F7F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:slc29a3
gene id: 8128:slc29a3
uniprot id: I3JUD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

8128:riox1
gene id: 8128:riox1
uniprot id: A0A669B6X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. NO66 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
messages: nucleolus

8128:atp6v1f
gene id: 8128:atp6v1f
uniprot id: A0A669EGV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8128:tbrg1
gene id: 8128:tbrg1
uniprot id: I3JCQ6
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100711978
gene id: 8128:LOC100711978
uniprot id: A0A669C3Z2
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

8128:snta1
gene id: 8128:snta1
uniprot id: I3JI75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

8128:hoxa13
gene id: 8128:hoxa13
uniprot id: A0A669B7P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8128:LOC100701524
gene id: 8128:LOC100701524
uniprot id: A0A669CW10
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:b4galt2
gene id: 8128:b4galt2
uniprot id: I3JS58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8128:rab38
gene id: 8128:rab38
uniprot id: I3JC47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8128:LOC100708184
gene id: 8128:LOC100708184
uniprot id: I3JKM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:eya3
gene id: 8128:eya3
uniprot id: A0A669CFK7
uniprot id: I3K803
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

8128:LOC102077830
gene id: 8128:LOC102077830
uniprot id: I3KAG7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100697197
gene id: 8128:LOC100697197
uniprot id: A0A669CJA2
uniprot id: A0A669CVG4
uniprot id: A0A669D709
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:hagh
gene id: 8128:hagh
uniprot id: I3KKQ9
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8128:rbp4
gene id: 8128:rbp4
uniprot id: I3KHT1
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8128:nuf2
gene id: 8128:nuf2
uniprot id: A0A669DKJ9
names: Similarity
messages: Belongs to the NUF2 family.

8128:nkx2-5
gene id: 8128:nkx2-5
uniprot id: I3KME6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NK-2 homeobox family.
messages: Nucleus

8128:LOC100705895
gene id: 8128:LOC100705895
uniprot id: I3JXE3
names: Similarity
messages: Belongs to the peptidase S28 family.

8128:ppil1
gene id: 8128:ppil1
uniprot id: A0A669CE69
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8128:LOC100691316
gene id: 8128:LOC100691316
uniprot id: A0A0E3JRK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted
messages: Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.

8128:znf703
gene id: 8128:znf703
uniprot id: A0A669CZ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

8128:ccnj
gene id: 8128:ccnj
uniprot id: I3KC38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8128:LOC100701613
gene id: 8128:LOC100701613
uniprot id: I3JH08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

8128:LOC100698925
gene id: 8128:LOC100698925
uniprot id: A0A669B7I8
names: Domain
names: Similarity
messages: Belongs to the Xin family.
messages: Xin repeats bind F-actin.

8128:epcam
gene id: 8128:epcam
uniprot id: A0A669D2W1
uniprot id: A0A669DKU9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:dars2
gene id: 8128:dars2
uniprot id: I3KIK8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

8128:arpc1a
gene id: 8128:arpc1a
uniprot id: A0A669C5T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

8128:pard3
gene id: 8128:pard3
uniprot id: I3J6X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

8128:akap9
gene id: 8128:akap9
uniprot id: A0A669C522
uniprot id: A0A669CVR8
names: Subcellular Location Annotation
messages: centrosome

8128:LOC100703167
gene id: 8128:LOC100703167
uniprot id: A0A669DRJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC100697673
gene id: 8128:LOC100697673
uniprot id: I3KWP2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

8128:pou4f1
gene id: 8128:pou4f1
uniprot id: A0A669BVY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8128:LOC100692669
gene id: 8128:LOC100692669
uniprot id: A0A669EJ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:aar2
gene id: 8128:aar2
uniprot id: A0A669DBC1
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

8128:LOC102080705
gene id: 8128:LOC102080705
uniprot id: A0A669CQJ0
names: Similarity
messages: Belongs to the ARTD/PARP family.

8128:sumf2
gene id: 8128:sumf2
uniprot id: A0A669D1G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

8128:LOC100697255
gene id: 8128:LOC100697255
uniprot id: I3JVL5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

8128:vps37a
gene id: 8128:vps37a
uniprot id: I3KH67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

8128:pcyox1
gene id: 8128:pcyox1
uniprot id: I3J6N4
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

8128:cul1
gene id: 8128:cul1
uniprot id: I3KMB9
names: Similarity
messages: Belongs to the cullin family.

8128:lg12h2orf68
gene id: 8128:lg12h2orf68
uniprot id: I3K6L6
names: Similarity
messages: Belongs to the UPF0561 family.

8128:LOC100693986
gene id: 8128:LOC100693986
uniprot id: I3KID1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:snrpd2
gene id: 8128:snrpd2
uniprot id: A0A669D448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

8128:LOC100690400
gene id: 8128:LOC100690400
uniprot id: A0A669BYV7
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

8128:LOC100694372
gene id: 8128:LOC100694372
uniprot id: I3K604
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: cytosol

8128:LOC100698626
gene id: 8128:LOC100698626
uniprot id: I3K6H1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

8128:ssbp2
gene id: 8128:ssbp2
uniprot id: A0A669EVQ2
names: Subcellular Location Annotation
messages: Nucleus

8128:tspan14
gene id: 8128:tspan14
uniprot id: I3JIT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100694460
gene id: 8128:LOC100694460
uniprot id: I3JWC2
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

8128:prss56
gene id: 8128:prss56
uniprot id: I3JUX8
names: Subcellular Location Annotation
messages: extracellular space

8128:minar1
gene id: 8128:minar1
uniprot id: A0A669BE11
names: Similarity
messages: Belongs to the MINAR family.

8128:LOC100704914
gene id: 8128:LOC100704914
uniprot id: A0A669CSM7
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:slc30a1
gene id: 8128:slc30a1
uniprot id: A0A669D7Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8128:pparg
gene id: 8128:pparg
uniprot id: W6EBH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8128:rngtt
gene id: 8128:rngtt
uniprot id: A0A669B394
uniprot id: A0A669BQT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

8128:dusp13
gene id: 8128:dusp13
uniprot id: I3KGY9
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8128:ankh
gene id: 8128:ankh
uniprot id: A0A669EZG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

8128:LOC100710693
gene id: 8128:LOC100710693
uniprot id: A0A669DXU8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100697825
gene id: 8128:LOC100697825
uniprot id: I3J545
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8128:LOC100700997
gene id: 8128:LOC100700997
uniprot id: I3J2D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

8128:slc7a14
gene id: 8128:slc7a14
uniprot id: I3IWX6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100700876
gene id: 8128:LOC100700876
uniprot id: I3KUP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

8128:sugt1
gene id: 8128:sugt1
uniprot id: I3KR02
names: Similarity
messages: Belongs to the SGT1 family.

8128:LOC100706109
gene id: 8128:LOC100706109
uniprot id: A0A669F5C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

8128:LOC109203849
gene id: 8128:LOC109203849
uniprot id: A0A669AVR8
names: Similarity
messages: Belongs to the peptidase M10A family.

8128:LOC100708121
gene id: 8128:LOC100708121
uniprot id: I3IZK2
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

8128:usp4
gene id: 8128:usp4
uniprot id: I3KS31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

8128:dr1
gene id: 8128:dr1
uniprot id: A0A669BJ13
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

8128:pde7b
gene id: 8128:pde7b
uniprot id: A0A669DEJ1
uniprot id: A0A669E4V7
uniprot id: A0A669E8D9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC100690322
gene id: 8128:LOC100690322
uniprot id: A0A669D3J9
uniprot id: I3KQP9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC100699682
gene id: 8128:LOC100699682
uniprot id: I3KQA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:adcy2
gene id: 8128:adcy2
uniprot id: A0A669D0K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8128:hsd17b12
gene id: 8128:hsd17b12
uniprot id: I3KET1
uniprot id: Q49RB0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:satb2
gene id: 8128:satb2
uniprot id: A0A669AY25
uniprot id: A0A669BYW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8128:LOC100709447
gene id: 8128:LOC100709447
uniprot id: I3JL75
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

8128:usp14
gene id: 8128:usp14
uniprot id: A0A669AWQ1
names: Similarity
names: Subunit
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
messages: Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS.

8128:LOC102083261
gene id: 8128:LOC102083261
uniprot id: I3J6G3
names: Similarity
messages: Belongs to the HEBP family.

8128:LOC100698516
gene id: 8128:LOC100698516
uniprot id: A0A669C098
uniprot id: A0A669C9Z5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8128:LOC100694454
gene id: 8128:LOC100694454
uniprot id: I3J7I7
names: Similarity
messages: Belongs to the HEBP family.

8128:lsm4
gene id: 8128:lsm4
uniprot id: I3K4G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

8128:rrh
gene id: 8128:rrh
uniprot id: A0A669EZF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8128:LOC100708190
gene id: 8128:LOC100708190
uniprot id: I3J4L9
names: Subcellular Location Annotation
messages: Nucleus

8128:ids
gene id: 8128:ids
uniprot id: A0A669DGC3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8128:LOC100709152
gene id: 8128:LOC100709152
uniprot id: A0A669BHI3
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

8128:rad52
gene id: 8128:rad52
uniprot id: I3KC09
names: Similarity
messages: Belongs to the RAD52 family.

8128:srp14
gene id: 8128:srp14
uniprot id: A0A669EUC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

8128:LOC100706002
gene id: 8128:LOC100706002
uniprot id: A0A669FAW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:mgat1
gene id: 8128:mgat1
uniprot id: I3J1Q3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

8128:LOC100690513
gene id: 8128:LOC100690513
uniprot id: I3JEU1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100704785
gene id: 8128:LOC100704785
uniprot id: A0A669C2U8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

8128:LOC100692269
gene id: 8128:LOC100692269
uniprot id: I3J9R5
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8128:aldh1l2
gene id: 8128:aldh1l2
uniprot id: I3K1V3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

8128:LOC100710863
gene id: 8128:LOC100710863
uniprot id: I3JCZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

8128:LOC100703100
gene id: 8128:LOC100703100
uniprot id: I3KQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

8128:LOC100692470
gene id: 8128:LOC100692470
uniprot id: I3KF36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8128:slc7a6os
gene id: 8128:slc7a6os
uniprot id: I3J552
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

8128:gclc
gene id: 8128:gclc
uniprot id: I3JTI9
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

8128:smpdl3b
gene id: 8128:smpdl3b
uniprot id: I3KH04
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

8128:ndufb3
gene id: 8128:ndufb3
uniprot id: A0A669B799
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

8128:LOC100704795
gene id: 8128:LOC100704795
uniprot id: I3JP45
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

8128:LOC100694299
gene id: 8128:LOC100694299
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:LOC100705554
gene id: 8128:LOC100705554
uniprot id: A0A669DBD5
names: Subcellular Location Annotation
messages: Membrane

8128:slc10a7
gene id: 8128:slc10a7
uniprot id: A0A669DJD2
uniprot id: I3K0U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Cell membrane
messages: Does not show transport activity towards bile acids or steroid sulfates.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

8128:LOC100704335
gene id: 8128:LOC100704335
uniprot id: I3JPJ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100705676
gene id: 8128:LOC100705676
uniprot id: A0A669BUK9
uniprot id: A0A669ET94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8128:LOC100700216
gene id: 8128:LOC100700216
uniprot id: I3KQB1
names: Similarity
messages: Belongs to the PPase family.

8128:gabrg2
gene id: 8128:gabrg2
uniprot id: A0A669EZ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100691717
gene id: 8128:LOC100691717
uniprot id: I3J8H2
uniprot id: I3J8H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:ube2b
gene id: 8128:ube2b
uniprot id: A0A669CEE7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:LOC100693281
gene id: 8128:LOC100693281
uniprot id: I3K9S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8128:akt1
gene id: 8128:akt1
uniprot id: A0A669EM09
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

8128:LOC100690465
gene id: 8128:LOC100690465
uniprot id: I3JC37
names: Subcellular Location Annotation
messages: Membrane

8128:arl2
gene id: 8128:arl2
uniprot id: I3K7D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

8128:LOC100694220
gene id: 8128:LOC100694220
uniprot id: I3KT21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to type I and type II collagen.
messages: extracellular matrix

8128:dap3
gene id: 8128:dap3
uniprot id: I3JGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

8128:iapp
gene id: 8128:iapp
uniprot id: A0A669CPH9
names: Function
names: Similarity
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

8128:rpf2
gene id: 8128:rpf2
uniprot id: A0A669F704
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

8128:ndufs2
gene id: 8128:ndufs2
uniprot id: I3KPP7
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

8128:LOC100690786
gene id: 8128:LOC100690786
uniprot id: A0A669C8V2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

8128:dmrta2
gene id: 8128:dmrta2
uniprot id: I3J267
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

8128:aifm1
gene id: 8128:aifm1
uniprot id: I3K501
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

8128:fam198a
gene id: 8128:fam198a
uniprot id: A0A669AV16
names: Similarity
messages: Belongs to the GASK family.

8128:cct5
gene id: 8128:cct5
uniprot id: A0A669AYJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8128:pfkfb3
gene id: 8128:pfkfb3
uniprot id: A0A669E380
uniprot id: I3K1B8
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8128:LOC100697091
gene id: 8128:LOC100697091
uniprot id: A0A669C684
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

8128:tinagl1
gene id: 8128:tinagl1
uniprot id: A0A669CF44
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:LOC106098040
gene id: 8128:LOC106098040
uniprot id: A0A669DLM8
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

8128:zdhhc3
gene id: 8128:zdhhc3
uniprot id: I3KUG1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC100697735
gene id: 8128:LOC100697735
uniprot id: I3IUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:adra1b
gene id: 8128:adra1b
uniprot id: A0A669CJ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

8128:LOC100703102
gene id: 8128:LOC100703102
uniprot id: I3KYT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100699212
gene id: 8128:LOC100699212
uniprot id: A0A669AW37
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100696606
gene id: 8128:LOC100696606
uniprot id: I3KWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:LOC100706095
gene id: 8128:LOC100706095
uniprot id: A0A669E7E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

8128:sigirr
gene id: 8128:sigirr
uniprot id: I3JNG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: Membrane

8128:LOC100707667
gene id: 8128:LOC100707667
uniprot id: A0A669E258
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100705425
gene id: 8128:LOC100705425
uniprot id: I3K297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:hnrnph1
gene id: 8128:hnrnph1
uniprot id: I3KMN9
names: Subcellular Location Annotation
messages: nucleoplasm

8128:LOC100697903
gene id: 8128:LOC100697903
uniprot id: I3KER0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:slc25a32
gene id: 8128:slc25a32
uniprot id: I3IU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:kif20a
gene id: 8128:kif20a
uniprot id: I3JCB6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:cmtm4
gene id: 8128:cmtm4
uniprot id: A0A669DAR1
names: Subcellular Location Annotation
messages: Membrane

8128:gtdc1
gene id: 8128:gtdc1
uniprot id: I3JEM3
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

8128:LOC100700667
gene id: 8128:LOC100700667
uniprot id: I3KAC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:cdk2ap1
gene id: 8128:cdk2ap1
uniprot id: A0A669B684
names: Similarity
messages: Belongs to the CDK2AP family.

8128:sgk2
gene id: 8128:sgk2
uniprot id: A0A669D525
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:slc26a5
gene id: 8128:slc26a5
uniprot id: I3JMN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

8128:LOC100709406
gene id: 8128:LOC100709406
uniprot id: I3IYE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

8128:cth
gene id: 8128:cth
uniprot id: A0A669EUB1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

8128:LOC100701398
gene id: 8128:LOC100701398
uniprot id: I3K3P0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8128:LOC100706728
gene id: 8128:LOC100706728
uniprot id: I3KH94
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

8128:osgep
gene id: 8128:osgep
uniprot id: I3K266
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least TP53RK, TPRKB, OSGEP and LAGE3; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
messages: Cytoplasm
messages: Nucleus

8128:fev
gene id: 8128:fev
uniprot id: A0A669DFY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:LOC100699955
gene id: 8128:LOC100699955
uniprot id: I3JX72
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100707472
gene id: 8128:LOC100707472
uniprot id: I3KLC9
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8128:LOC102080377
gene id: 8128:LOC102080377
uniprot id: A0A669CKK5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100709519
gene id: 8128:LOC100709519
uniprot id: I3J8R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

8128:LOC100534448
gene id: 8128:LOC100534448
uniprot id: D3TJN8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8128:arl5a
gene id: 8128:arl5a
uniprot id: A0A669F3K1
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8128:pkd2
gene id: 8128:pkd2
uniprot id: I3KLL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Cell membrane
messages: Membrane
messages: cilium membrane

8128:pcsk2
gene id: 8128:pcsk2
uniprot id: I3IUZ6
names: Similarity
messages: Belongs to the peptidase S8 family.

8128:snx6
gene id: 8128:snx6
uniprot id: I3JYE0
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

8128:traf6
gene id: 8128:traf6
uniprot id: I3JEV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

8128:LOC100691481
gene id: 8128:LOC100691481
uniprot id: A0A669BB12
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8128:taf4
gene id: 8128:taf4
uniprot id: A0A669ENR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

8128:LOC100700644
gene id: 8128:LOC100700644
uniprot id: A0A669AW21
names: Similarity
messages: Belongs to the PPDPF family.

8128:LOC100711859
gene id: 8128:LOC100711859
uniprot id: I3JLE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.

8128:LOC100534577
gene id: 8128:LOC100534577
uniprot id: I3K5D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:cpped1
gene id: 8128:cpped1
uniprot id: I3KUS8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.

8128:capza2
gene id: 8128:capza2
uniprot id: A0A669C8N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

8128:LOC100704491
gene id: 8128:LOC100704491
uniprot id: A0A669DVW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

8128:cpn1
gene id: 8128:cpn1
uniprot id: A0A669EWQ9
names: Similarity
messages: Belongs to the peptidase M14 family.

8128:LOC106097921
gene id: 8128:LOC106097921
uniprot id: I3K1G2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:LOC100711262
gene id: 8128:LOC100711262
uniprot id: A0A669DGW1
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

8128:samd4a
gene id: 8128:samd4a
uniprot id: A0A669F6R0
uniprot id: I3JJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

8128:LOC100702055
gene id: 8128:LOC100702055
uniprot id: I3JWT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

8128:kctd10
gene id: 8128:kctd10
uniprot id: A0A669DCS9
names: Similarity
messages: Belongs to the BACURD family.

8128:lacc1
gene id: 8128:lacc1
uniprot id: I3KGV1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

8128:slc6a17
gene id: 8128:slc6a17
uniprot id: A0A669C5H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC100695332
gene id: 8128:LOC100695332
uniprot id: A0A669DD91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

8128:LOC100709793
gene id: 8128:LOC100709793
uniprot id: I3KFR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Membrane

8128:LOC100534398
gene id: 8128:LOC100534398
uniprot id: A0A669B0L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

8128:ndufaf4
gene id: 8128:ndufaf4
uniprot id: A0A669F2C8
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

8128:LOC100692674
gene id: 8128:LOC100692674
uniprot id: I3KVG2
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

8128:LOC100711397
gene id: 8128:LOC100711397
uniprot id: A0A669E5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:cmtm3
gene id: 8128:cmtm3
uniprot id: A0A669EA84
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100699154
gene id: 8128:LOC100699154
uniprot id: A0A669B745
uniprot id: A0A669B9A4
uniprot id: A0A669EU10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nectin family.
messages: Membrane

8128:odr4
gene id: 8128:odr4
uniprot id: I3KIG1
names: Function
names: Similarity
messages: Belongs to the ODR-4 family.
messages: May play a role in the trafficking of a subset of G-protein coupled receptors.

8128:LOC100705329
gene id: 8128:LOC100705329
uniprot id: A0A669EC38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8128:LOC100696093
gene id: 8128:LOC100696093
uniprot id: I3K2L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

8128:LOC100704054
gene id: 8128:LOC100704054
uniprot id: A0A669DNN1
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:wdr46
gene id: 8128:wdr46
uniprot id: I3KKV2
names: Subcellular Location Annotation
messages: nucleolus

8128:mogat2
gene id: 8128:mogat2
uniprot id: I3JZH1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100697082
gene id: 8128:LOC100697082
uniprot id: I3JET7
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

8128:pigc
gene id: 8128:pigc
uniprot id: I3J3P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

8128:pdc
gene id: 8128:pdc
uniprot id: I3JUR0
names: Similarity
messages: Belongs to the phosducin family.

8128:LOC100708116
gene id: 8128:LOC100708116
uniprot id: I3J6Y0
names: Similarity
messages: Belongs to the peptidase C14A family.

8128:LOC100710835
gene id: 8128:LOC100710835
uniprot id: A0A669ETB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

8128:cltb
gene id: 8128:cltb
uniprot id: A0A669BS30
uniprot id: A0A669C2Q8
uniprot id: A0A669CV51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

8128:ppp3r1
gene id: 8128:ppp3r1
uniprot id: A0A669B2I9
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

8128:LOC100697335
gene id: 8128:LOC100697335
uniprot id: I3JYA3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

8128:pcna
gene id: 8128:pcna
uniprot id: A0A669EG94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

8128:LOC100693075
gene id: 8128:LOC100693075
uniprot id: I3J5L3
names: Subcellular Location Annotation
messages: Membrane

8128:itgav
gene id: 8128:itgav
uniprot id: A0A669DY15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:LOC100709493
gene id: 8128:LOC100709493
uniprot id: I3JUL7
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:cemip2
gene id: 8128:cemip2
uniprot id: A0A669CVC4
names: Similarity
messages: Belongs to the CEMIP family.

8128:LOC109203641
gene id: 8128:LOC109203641
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:mc1r
gene id: 8128:mc1r
uniprot id: I3KZZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

8128:nppc
gene id: 8128:nppc
uniprot id: A0A669E8F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

8128:LOC100700462
gene id: 8128:LOC100700462
uniprot id: A0A669EQ53
names: Similarity
messages: Belongs to the GADD45 family.

8128:LOC100690575
gene id: 8128:LOC100690575
uniprot id: A0A669CWZ4
names: Subcellular Location Annotation
messages: Membrane

8128:rnf34
gene id: 8128:rnf34
uniprot id: I3JXL7
uniprot id: I3JXL8
names: Subcellular Location Annotation
messages: Cell membrane

8128:dgat2
gene id: 8128:dgat2
uniprot id: I3JZG8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:gle1
gene id: 8128:gle1
uniprot id: A0A669DSA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

8128:LOC100696822
gene id: 8128:LOC100696822
uniprot id: I3JK42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:lrfn1
gene id: 8128:lrfn1
uniprot id: I3JYL8
names: Subcellular Location Annotation
messages: Membrane

8128:rev3l
gene id: 8128:rev3l
uniprot id: A0A669E491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

8128:LOC100694836
gene id: 8128:LOC100694836
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:LOC100704269
gene id: 8128:LOC100704269
uniprot id: I3KHA7
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8128:mmaa
gene id: 8128:mmaa
uniprot id: I3JUN4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

8128:gata4
gene id: 8128:gata4
uniprot id: A8DS45
names: Subcellular Location Annotation
messages: Nucleus

8128:mcam
gene id: 8128:mcam
uniprot id: A0A669BPB8
uniprot id: A0A669C0Z7
uniprot id: A0A669D4Y8
uniprot id: A0A669F5I3
uniprot id: I3JG45
uniprot id: I3JG46
names: Subcellular Location Annotation
messages: Membrane

8128:lgi3
gene id: 8128:lgi3
uniprot id: I3JYB0
names: Subcellular Location Annotation
messages: Secreted

8128:LOC100705155
gene id: 8128:LOC100705155
uniprot id: I3K296
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

8128:entpd1
gene id: 8128:entpd1
uniprot id: A0A669EZK1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8128:LOC100705775
gene id: 8128:LOC100705775
uniprot id: A0A669EMX6
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

8128:LOC100689910
gene id: 8128:LOC100689910
uniprot id: I3KD46
names: Subcellular Location Annotation
messages: Membrane

8128:coq10b
gene id: 8128:coq10b
uniprot id: I3K866
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

8128:kansl2
gene id: 8128:kansl2
uniprot id: I3KI70
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

8128:LOC100698585
gene id: 8128:LOC100698585
uniprot id: A0A669EEP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

8128:LOC100703058
gene id: 8128:LOC100703058
uniprot id: A0A669BH76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:rrp12
gene id: 8128:rrp12
uniprot id: I3JSX8
names: Similarity
messages: Belongs to the RRP12 family.

8128:ston1
gene id: 8128:ston1
uniprot id: I3JU32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: May be involved in the endocytic machinery.

8128:LOC102081706
gene id: 8128:LOC102081706
uniprot id: A0A669AZM0
uniprot id: A0A669D7K2
uniprot id: A0A669DHG2
names: Similarity
messages: Belongs to the FAM161 family.

8128:dnm3
gene id: 8128:dnm3
uniprot id: A0A669D5U0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8128:LOC100693277
gene id: 8128:LOC100693277
uniprot id: A0A669ECK2
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC109195020
gene id: 8128:LOC109195020
uniprot id: A0A669E292
names: Similarity
messages: Belongs to the peptidase S1B family.

8128:LOC100711363
gene id: 8128:LOC100711363
uniprot id: A0A669EF85
uniprot id: I3IW54
names: Similarity
messages: Belongs to the SOGA family.

8128:cnot11
gene id: 8128:cnot11
uniprot id: A0A669BHJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100693479
gene id: 8128:LOC100693479
uniprot id: I3KYU0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:ldlr
gene id: 8128:ldlr
uniprot id: I3JN97
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100706178
gene id: 8128:LOC100706178
uniprot id: I3IX63
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:cct7
gene id: 8128:cct7
uniprot id: I3Y506
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

8128:LOC100702113
gene id: 8128:LOC100702113
uniprot id: I3JG39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

8128:LOC100703644
gene id: 8128:LOC100703644
uniprot id: I3K9Q3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8128:LOC100697502
gene id: 8128:LOC100697502
uniprot id: I3IW57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8128:hnf1b
gene id: 8128:hnf1b
uniprot id: A0A669BVT1
uniprot id: A0A669E3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

8128:LOC100695278
gene id: 8128:LOC100695278
uniprot id: A0A669BDY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Oligomer.

8128:LOC100707465
gene id: 8128:LOC100707465
uniprot id: I3J8M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

8128:snap23
gene id: 8128:snap23
uniprot id: I3IX07
uniprot id: I3IX08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: synaptosome

8128:LOC100700497
gene id: 8128:LOC100700497
uniprot id: I3K6P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:LOC106097693
gene id: 8128:LOC106097693
uniprot id: I3JGV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

8128:rxfp1
gene id: 8128:rxfp1
uniprot id: A0A669DZI6
uniprot id: I3IY71
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100708708
gene id: 8128:LOC100708708
uniprot id: A0A669DW39
names: Similarity
messages: Belongs to the BZW family.

8128:lg18h1orf123
gene id: 8128:lg18h1orf123
uniprot id: A0A669CC61
names: Similarity
messages: Belongs to the UPF0587 family.

8128:rab18
gene id: 8128:rab18
uniprot id: I3J744
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

8128:LOC100690457
gene id: 8128:LOC100690457
uniprot id: I3K9V5
names: Subcellular Location Annotation
messages: extracellular space

8128:btg3
gene id: 8128:btg3
uniprot id: I3K8K6
names: Similarity
messages: Belongs to the BTG family.

8128:rab27a
gene id: 8128:rab27a
uniprot id: A0A669AWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

8128:LOC100704088
gene id: 8128:LOC100704088
uniprot id: A0A669F0J2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8128:LOC109203870
gene id: 8128:LOC109203870
uniprot id: A0A669DE93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8128:slc25a13
gene id: 8128:slc25a13
uniprot id: A0A669DN11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8128:acot13
gene id: 8128:acot13
uniprot id: A0A669E1D5
names: Similarity
messages: Belongs to the thioesterase PaaI family.

8128:khsrp
gene id: 8128:khsrp
uniprot id: I3J1F5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC106096465
gene id: 8128:LOC106096465
uniprot id: A0A669DDI7
names: Similarity
messages: Belongs to the MHC class I family.

8128:LOC100708619
gene id: 8128:LOC100708619
uniprot id: A0A669CEZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8128:granzyme
gene id: 8128:granzyme
uniprot id: G7Z062
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100712562
gene id: 8128:LOC100712562
uniprot id: A0A669E8T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

8128:LOC100696106
gene id: 8128:LOC100696106
uniprot id: I3KH42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-III AFP family.
messages: Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point. Binds to nascent ice crystals and prevents further growth.
messages: Secreted

8128:LOC100702196
gene id: 8128:LOC100702196
uniprot id: A0A669CSG5
names: Similarity
messages: Belongs to the AAA ATPase family.

8128:LOC100693919
gene id: 8128:LOC100693919
uniprot id: I3IUU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8128:LOC100702519
gene id: 8128:LOC100702519
uniprot id: I3KTF4
names: Similarity
messages: Belongs to the intermediate filament family.

8128:gpr83
gene id: 8128:gpr83
uniprot id: A0A669C666
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8128:LOC100690937
gene id: 8128:LOC100690937
uniprot id: A0A669BAQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8128:nop56
gene id: 8128:nop56
uniprot id: I3KX47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

8128:pou2f3
gene id: 8128:pou2f3
uniprot id: I3KL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

8128:LOC100700171
gene id: 8128:LOC100700171
uniprot id: A0A669E4Z6
names: Similarity
messages: Belongs to the FAM83 family.

8128:ppm1e
gene id: 8128:ppm1e
uniprot id: I3KL85
names: Similarity
messages: Belongs to the PP2C family.

8128:LOC100534412
gene id: 8128:LOC100534412
uniprot id: I3J505
names: Similarity
messages: Belongs to the actin family.

8128:LOC100706414
gene id: 8128:LOC100706414
uniprot id: I3IUS0
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8128:ptpn21
gene id: 8128:ptpn21
uniprot id: A0A669DLL6
uniprot id: I3IYU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

8128:LOC100706297
gene id: 8128:LOC100706297
uniprot id: A0A669CSL9
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:plpp4
gene id: 8128:plpp4
uniprot id: A0A669FA72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:LOC100698754
gene id: 8128:LOC100698754
uniprot id: A0A669C233
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8128:ccs
gene id: 8128:ccs
uniprot id: A0A669DIP2
names: Similarity
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.

8128:LOC100710620
gene id: 8128:LOC100710620
uniprot id: I3JIE1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

8128:LOC100709027
gene id: 8128:LOC100709027
uniprot id: A0A669AXB3
names: Similarity
messages: Belongs to the TPPP family.

8128:pex19
gene id: 8128:pex19
uniprot id: I3KDB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

8128:slc25a40
gene id: 8128:slc25a40
uniprot id: I3JFX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:fabp1
gene id: 8128:fabp1
uniprot id: I3KDH3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

8128:eml3
gene id: 8128:eml3
uniprot id: A0A669CWM6
uniprot id: I3J7H3
names: Similarity
messages: Belongs to the WD repeat EMAP family.

8128:ptpra
gene id: 8128:ptpra
uniprot id: I3KX25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100698412
gene id: 8128:LOC100698412
uniprot id: I3KP30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100702798
gene id: 8128:LOC100702798
uniprot id: A0A669EBH1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:stra6
gene id: 8128:stra6
uniprot id: I3KE07
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:mrm2
gene id: 8128:mrm2
uniprot id: A0A669EBG5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

8128:LOC100700186
gene id: 8128:LOC100700186
uniprot id: I3KSV7
names: Similarity
messages: Belongs to the glutamine synthetase family.

8128:LOC100706531
gene id: 8128:LOC100706531
uniprot id: A0A669B176
names: Similarity
messages: Belongs to the FAX family.

8128:LOC100704024
gene id: 8128:LOC100704024
uniprot id: I3KFF7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100701771
gene id: 8128:LOC100701771
uniprot id: I3JGL2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100694607
gene id: 8128:LOC100694607
uniprot id: A0A669DQP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Membrane
messages: Mitochondrion inner membrane

8128:ak4
gene id: 8128:ak4
uniprot id: I3JQB8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion matrix
messages: Monomer.

8128:LOC100692842
gene id: 8128:LOC100692842
uniprot id: I3JTC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC102081201
gene id: 8128:LOC102081201
uniprot id: I3JXV1
names: Similarity
messages: Belongs to the SEC6 family.

8128:atg4b
gene id: 8128:atg4b
uniprot id: A0A669E9M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: autophagosome
messages: cytosol

8128:LOC100699505
gene id: 8128:LOC100699505
uniprot id: A0A669EBD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

8128:mrpl4
gene id: 8128:mrpl4
uniprot id: A0A669B5X1
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

8128:LOC100698095
gene id: 8128:LOC100698095
uniprot id: I3K6F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8128:LOC102076869
gene id: 8128:LOC102076869
uniprot id: I3JS96
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:dna2
gene id: 8128:dna2
uniprot id: A0A669BMN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Mitochondrion
messages: Nucleus

8128:LOC100695648
gene id: 8128:LOC100695648
uniprot id: A0A669EFK9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:adck5
gene id: 8128:adck5
uniprot id: I3JLE0
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8128:mstn
gene id: 8128:mstn
uniprot id: A0A669DVE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

8128:LOC102079881
gene id: 8128:LOC102079881
uniprot id: I3KDX3
names: Similarity
messages: Belongs to the LCA5 family.

8128:LOC100696021
gene id: 8128:LOC100696021
uniprot id: I3K4X4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:pth2
gene id: 8128:pth2
uniprot id: Q24K57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8128:LOC100696018
gene id: 8128:LOC100696018
uniprot id: I3KXD7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100698089
gene id: 8128:LOC100698089
uniprot id: A0A669EKV9
names: Subcellular Location Annotation
messages: Nucleus

8128:ptprk
gene id: 8128:ptprk
uniprot id: A0A669CL27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

8128:LOC100696971
gene id: 8128:LOC100696971
uniprot id: A0A669DU61
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:LOC100693282
gene id: 8128:LOC100693282
uniprot id: I3JZ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Lysosome
messages: cytosol
messages: extracellular exosome

8128:slc7a9
gene id: 8128:slc7a9
uniprot id: I3J2E8
names: Subcellular Location Annotation
messages: Membrane

8128:mrpl30
gene id: 8128:mrpl30
uniprot id: A0A669B374
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

8128:LOC100695726
gene id: 8128:LOC100695726
uniprot id: I3IVT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8128:LOC100711895
gene id: 8128:LOC100711895
uniprot id: A0A669DWC8
names: Similarity
messages: Belongs to the p23/wos2 family.

8128:kirrel2
gene id: 8128:kirrel2
uniprot id: A0A669D2T6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100692768
gene id: 8128:LOC100692768
uniprot id: A0A669CAV0
names: Subcellular Location Annotation
messages: Synapse

8128:rrp8
gene id: 8128:rrp8
uniprot id: I3KJF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Probable methyltransferase required to silence rDNA.
messages: nucleolus

8128:babam1
gene id: 8128:babam1
uniprot id: I3JV16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BABAM1 family.
messages: Nucleus

8128:LOC102080222
gene id: 8128:LOC102080222
uniprot id: A0A669CKH1
names: Similarity
messages: Belongs to the globin family.

8128:otud7b
gene id: 8128:otud7b
uniprot id: A0A669BQI9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:p3h2
gene id: 8128:p3h2
uniprot id: I3IZV6
names: Similarity
messages: Belongs to the leprecan family.

8128:LOC102080261
gene id: 8128:LOC102080261
uniprot id: I3KD31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

8128:LOC100693800
gene id: 8128:LOC100693800
uniprot id: I3JZB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

8128:LOC100705055
gene id: 8128:LOC100705055
uniprot id: I3KZX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

8128:LOC100691981
gene id: 8128:LOC100691981
uniprot id: A0A669DN32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC100703788
gene id: 8128:LOC100703788
uniprot id: I3K1R3
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

8128:LOC100700821
gene id: 8128:LOC100700821
uniprot id: A0A669B5Z3
names: Subcellular Location Annotation
messages: Membrane

8128:tmem131l
gene id: 8128:tmem131l
uniprot id: I3JU60
names: Similarity
messages: Belongs to the TMEM131 family.

8128:LOC100709874
gene id: 8128:LOC100709874
uniprot id: I3KMF0
names: Similarity
messages: Belongs to the RRM CPEB family.

8128:LOC100692739
gene id: 8128:LOC100692739
uniprot id: I3KF40
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:rab3ip
gene id: 8128:rab3ip
uniprot id: A0A669B1E6
uniprot id: A0A669BE58
uniprot id: I3KNG7
names: Similarity
messages: Belongs to the SEC2 family.

8128:LOC100711201
gene id: 8128:LOC100711201
uniprot id: A0A669E4W4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100710600
gene id: 8128:LOC100710600
uniprot id: A0A669E6R6
uniprot id: I3JM51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

8128:zic2
gene id: 8128:zic2
uniprot id: I3JI73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

8128:LOC100692424
gene id: 8128:LOC100692424
uniprot id: I3IVA3
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8128:paip2b
gene id: 8128:paip2b
uniprot id: I3K7H0
names: Similarity
messages: Belongs to the PAIP2 family.

8128:ovol1
gene id: 8128:ovol1
uniprot id: I3ITV6
names: Subcellular Location Annotation
messages: Nucleus

8128:ctnnb1
gene id: 8128:ctnnb1
uniprot id: I3JJR7
names: Similarity
messages: Belongs to the beta-catenin family.

8128:LOC100712047
gene id: 8128:LOC100712047
uniprot id: A0A669BFE6
uniprot id: I3IWU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: cytoskeleton

8128:LOC100695190
gene id: 8128:LOC100695190
uniprot id: I3KKV7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:fdft1
gene id: 8128:fdft1
uniprot id: A0A669BDV8
uniprot id: A0A669F091
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

8128:ccdc25
gene id: 8128:ccdc25
uniprot id: A0A669CNA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

8128:LOC100711474
gene id: 8128:LOC100711474
uniprot id: I3JVQ6
names: Subcellular Location Annotation
messages: Membrane

8128:ran
gene id: 8128:ran
uniprot id: A0A669CSQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

8128:LOC100690838
gene id: 8128:LOC100690838
uniprot id: A0A669AZW8
uniprot id: A0A669B3L9
uniprot id: A0A669BK33
uniprot id: A0A669CIV5
uniprot id: A0A669D9K1
uniprot id: A0A669ETN5
uniprot id: I3KNT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

8128:LOC100708854
gene id: 8128:LOC100708854
uniprot id: I3KKF9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8128:nlgn3
gene id: 8128:nlgn3
uniprot id: A0A669C5E0
uniprot id: A0A669F8H4
uniprot id: I3KMX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8128:ddost
gene id: 8128:ddost
uniprot id: I3JHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

8128:LOC100710315
gene id: 8128:LOC100710315
uniprot id: I3KZ18
names: Subcellular Location Annotation
messages: Nucleus

8128:lck
gene id: 8128:lck
uniprot id: I3JN72
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:arap1
gene id: 8128:arap1
uniprot id: I3KIW8
uniprot id: I3KIW9
uniprot id: I3KIX0
names: Subcellular Location Annotation
messages: Cytoplasm

8128:crbn
gene id: 8128:crbn
uniprot id: A0A669BV84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

8128:trmt1
gene id: 8128:trmt1
uniprot id: A0A669E1E2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

8128:LOC100708685
gene id: 8128:LOC100708685
uniprot id: I3KZ13
names: Function
messages: Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.

8128:mrpl44
gene id: 8128:mrpl44
uniprot id: I3JDW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

8128:LOC102078258
gene id: 8128:LOC102078258
uniprot id: A0A669EGZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

8128:mlec
gene id: 8128:mlec
uniprot id: I3JZ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100699056
gene id: 8128:LOC100699056
uniprot id: I3K959
names: Similarity
messages: Belongs to the beta-catenin family.

8128:surf4
gene id: 8128:surf4
uniprot id: A0A669F2X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

8128:nit1
gene id: 8128:nit1
uniprot id: I3K5H5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

8128:LOC100696727
gene id: 8128:LOC100696727
uniprot id: I3KY78
names: Subcellular Location Annotation
messages: Membrane

8128:asphd2
gene id: 8128:asphd2
uniprot id: I3JZ24
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

8128:LOC100708271
gene id: 8128:LOC100708271
uniprot id: I3JLG9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100709287
gene id: 8128:LOC100709287
uniprot id: I3KL70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8128:ndufb5
gene id: 8128:ndufb5
uniprot id: I3IZS3
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB5 subunit family.
messages: Complex I is composed of 45 different subunits.

8128:LOC102082779
gene id: 8128:LOC102082779
uniprot id: A0A669CZU0
names: Subcellular Location Annotation
messages: Membrane

8128:cdh22
gene id: 8128:cdh22
uniprot id: I3JIA2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8128:LOC100698344
gene id: 8128:LOC100698344
uniprot id: I3KQ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8128:LOC100709506
gene id: 8128:LOC100709506
uniprot id: A0A669AYL1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

8128:LOC100690908
gene id: 8128:LOC100690908
uniprot id: I3IYI6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8128:fam149b1
gene id: 8128:fam149b1
uniprot id: I3IWF7
uniprot id: I3IWF8
names: Similarity
messages: Belongs to the FAM149 family.

8128:LOC100693503
gene id: 8128:LOC100693503
uniprot id: A0A669AX82
names: Similarity
messages: Belongs to the MAGUK family.

8128:hip1
gene id: 8128:hip1
uniprot id: A0A669EIW5
names: Similarity
messages: Belongs to the SLA2 family.

8128:LOC100705513
gene id: 8128:LOC100705513
uniprot id: I3JGI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:il1rap
gene id: 8128:il1rap
uniprot id: I3IXZ6
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

8128:fam171a1
gene id: 8128:fam171a1
uniprot id: A0A669DAL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

8128:taf7l
gene id: 8128:taf7l
uniprot id: I3J3A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

8128:tm9sf2
gene id: 8128:tm9sf2
uniprot id: A0A669BKI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

8128:LOC100698818
gene id: 8128:LOC100698818
uniprot id: A0A669BKK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

8128:atp1b2
gene id: 8128:atp1b2
uniprot id: I3J8Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8128:gng8
gene id: 8128:gng8
uniprot id: I3JBR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8128:LOC100711508
gene id: 8128:LOC100711508
uniprot id: A0A669EUJ3
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

8128:LOC100693977
gene id: 8128:LOC100693977
uniprot id: A0A669AW35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPPP family.
messages: cytoskeleton

8128:LOC100709373
gene id: 8128:LOC100709373
uniprot id: I3KYH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:LOC102076498
gene id: 8128:LOC102076498
uniprot id: I3JDV5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8128:psma2
gene id: 8128:psma2
uniprot id: I3JJY5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8128:LOC100697678
gene id: 8128:LOC100697678
uniprot id: A0A669BS50
uniprot id: I3J1U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

8128:LOC100695221
gene id: 8128:LOC100695221
uniprot id: A0A669F9X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Binds strongly to apatite and calcium.
messages: Secreted

8128:casd1
gene id: 8128:casd1
uniprot id: A0A669F1Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane

8128:LOC100711209
gene id: 8128:LOC100711209
uniprot id: A0A669BRW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8128:LOC100704594
gene id: 8128:LOC100704594
uniprot id: I3KZC9
names: Subcellular Location Annotation
messages: Membrane

8128:vamp4
gene id: 8128:vamp4
uniprot id: I3J3M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8128:armc1
gene id: 8128:armc1
uniprot id: I3K9M6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8128:KEH09 p02
gene id: 8128:KEH09_p02
uniprot id: D2KP35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

8128:ror2
gene id: 8128:ror2
uniprot id: I3JZ34
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100691083
gene id: 8128:LOC100691083
uniprot id: A0A669EFA7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

8128:rnaseh2a
gene id: 8128:rnaseh2a
uniprot id: I3KNM9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

8128:b3galt6
gene id: 8128:b3galt6
uniprot id: I3KZD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:adipor2
gene id: 8128:adipor2
uniprot id: I3K0X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8128:opn1sw
gene id: 8128:opn1sw
uniprot id: F8TJW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

8128:LOC100699906
gene id: 8128:LOC100699906
uniprot id: I3KSA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8128:LOC100708564
gene id: 8128:LOC100708564
uniprot id: A0A669BAH6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100701700
gene id: 8128:LOC100701700
uniprot id: A0A669DFS7
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

8128:acod1
gene id: 8128:acod1
uniprot id: A0A669BVS6
names: Similarity
messages: Belongs to the PrpD family.

8128:dlx2
gene id: 8128:dlx2
uniprot id: A0A669EET9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8128:LOC100695821
gene id: 8128:LOC100695821
uniprot id: A0A669CHS1
uniprot id: A0A669E312
uniprot id: I3J9J3
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:hoxb1
gene id: 8128:hoxb1
uniprot id: I3KP89
names: Subcellular Location Annotation
messages: Nucleus

8128:pik3c2a
gene id: 8128:pik3c2a
uniprot id: I3KEN4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8128:LOC100693184
gene id: 8128:LOC100693184
uniprot id: I3KQS9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8128:gng2
gene id: 8128:gng2
uniprot id: A0A669E7U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8128:ppa2
gene id: 8128:ppa2
uniprot id: I3KLW5
names: Similarity
messages: Belongs to the PPase family.

8128:LOC100695155
gene id: 8128:LOC100695155
uniprot id: I3KFE2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:LOC100699719
gene id: 8128:LOC100699719
uniprot id: I3KJR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8128:zer1
gene id: 8128:zer1
uniprot id: A0A669DMB5
names: Similarity
messages: Belongs to the zyg-11 family.

8128:LOC100708457
gene id: 8128:LOC100708457
uniprot id: A0A669F648
names: Subcellular Location Annotation
messages: Membrane

8128:ndufa5
gene id: 8128:ndufa5
uniprot id: I3K9P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8128:LOC100699693
gene id: 8128:LOC100699693
uniprot id: A0A669DE62
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

8128:polr1e
gene id: 8128:polr1e
uniprot id: I3JQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

8128:LOC100710188
gene id: 8128:LOC100710188
uniprot id: I3JJN9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:nkx2-3
gene id: 8128:nkx2-3
uniprot id: A0A669CZE5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100710204
gene id: 8128:LOC100710204
uniprot id: I3KGA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

8128:mrpl3
gene id: 8128:mrpl3
uniprot id: I3J122
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

8128:LOC100695723
gene id: 8128:LOC100695723
uniprot id: A0A669EPG7
uniprot id: I3J1J0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

8128:LOC100693310
gene id: 8128:LOC100693310
uniprot id: I3JNM3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:dlx5
gene id: 8128:dlx5
uniprot id: A0A669CUQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8128:treh
gene id: 8128:treh
uniprot id: I3JEG0
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

8128:LOC100692715
gene id: 8128:LOC100692715
uniprot id: I3K367
names: Subcellular Location Annotation
messages: Membrane

8128:tbca
gene id: 8128:tbca
uniprot id: I3KEB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

8128:LOC100711902
gene id: 8128:LOC100711902
uniprot id: A0A669DZM9
names: Subcellular Location Annotation
messages: extracellular space

8128:ntrk3
gene id: 8128:ntrk3
uniprot id: I3J4H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100707048
gene id: 8128:LOC100707048
uniprot id: A0A669BN11
uniprot id: A0A669ERZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

8128:LOC100704523
gene id: 8128:LOC100704523
uniprot id: A0A669BIU9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

8128:dars
gene id: 8128:dars
uniprot id: I3J9K3
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

8128:lamc1
gene id: 8128:lamc1
uniprot id: A0A669BFJ5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

8128:LOC100695035
gene id: 8128:LOC100695035
uniprot id: A0A669BEX6
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

8128:masp2
gene id: 8128:masp2
uniprot id: I3J215
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:edem1
gene id: 8128:edem1
uniprot id: A0A669EPC0
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8128:raf1
gene id: 8128:raf1
uniprot id: I3KKK9
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

8128:vps26c
gene id: 8128:vps26c
uniprot id: I3KL78
names: Similarity
messages: Belongs to the VPS26 family.

8128:LOC100703162
gene id: 8128:LOC100703162
uniprot id: I3JYV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

8128:LOC100702942
gene id: 8128:LOC100702942
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:LOC100702284
gene id: 8128:LOC100702284
uniprot id: I3JCT9
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

8128:LOC100709861
gene id: 8128:LOC100709861
uniprot id: A0A669EVL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:rrn3
gene id: 8128:rrn3
uniprot id: A0A669D4L1
names: Similarity
messages: Belongs to the RRN3 family.

8128:LOC100706381
gene id: 8128:LOC100706381
uniprot id: A0A669CSD5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8128:pspc1
gene id: 8128:pspc1
uniprot id: I3K1X3
names: Subcellular Location Annotation
messages: Nucleus speckle

8128:LOC100700431
gene id: 8128:LOC100700431
uniprot id: A0A669EH34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

8128:arl6ip5
gene id: 8128:arl6ip5
uniprot id: A0A669FCV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8128:otc
gene id: 8128:otc
uniprot id: I3K9Z9
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

8128:LOC100708525
gene id: 8128:LOC100708525
uniprot id: I3KME3
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

8128:LOC100700221
gene id: 8128:LOC100700221
uniprot id: A0A669E9D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8128:LOC100708615
gene id: 8128:LOC100708615
uniprot id: I3JCB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:snrnp200
gene id: 8128:snrnp200
uniprot id: I3JX75
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

8128:rbpms2
gene id: 8128:rbpms2
uniprot id: A0A669EYP6
uniprot id: I3JEH9
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100695807
gene id: 8128:LOC100695807
uniprot id: A0A669CLK0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:shoc2
gene id: 8128:shoc2
uniprot id: I3KHB1
names: Function
names: Similarity
messages: Belongs to the SHOC2 family.
messages: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

8128:g2e3
gene id: 8128:g2e3
uniprot id: I3J0C6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100693663
gene id: 8128:LOC100693663
uniprot id: I3KUC0
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100699208
gene id: 8128:LOC100699208
uniprot id: I3JQE2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100704356
gene id: 8128:LOC100704356
uniprot id: A0A669BZJ9
uniprot id: I3JDQ2
names: Subcellular Location Annotation
messages: extracellular matrix

8128:ccnb3
gene id: 8128:ccnb3
uniprot id: I3JIQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8128:LOC100692795
gene id: 8128:LOC100692795
uniprot id: A0A669ELZ5
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

8128:cemip
gene id: 8128:cemip
uniprot id: I3J0T0
names: Similarity
messages: Belongs to the CEMIP family.

8128:bccip
gene id: 8128:bccip
uniprot id: I3KGB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: spindle pole

8128:LOC102083160
gene id: 8128:LOC102083160
uniprot id: I3JJZ3
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:ccdc47
gene id: 8128:ccdc47
uniprot id: I3JU39
names: Subcellular Location Annotation
messages: Membrane
messages: Rough endoplasmic reticulum membrane

8128:gadd45b
gene id: 8128:gadd45b
uniprot id: I3JK22
names: Similarity
messages: Belongs to the GADD45 family.

8128:gchfr
gene id: 8128:gchfr
uniprot id: A0A669AZ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

8128:cdc6
gene id: 8128:cdc6
uniprot id: I3ITZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
messages: Nucleus

8128:LOC100696688
gene id: 8128:LOC100696688
uniprot id: A0A669E070
uniprot id: I3J2P9
names: Similarity
messages: Belongs to the MAGUK family.

8128:LOC100697412
gene id: 8128:LOC100697412
uniprot id: I3J1R6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:ndufa13
gene id: 8128:ndufa13
uniprot id: I3JV91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

8128:ppil4
gene id: 8128:ppil4
uniprot id: I3JZQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8128:ap3b1
gene id: 8128:ap3b1
uniprot id: I3KEB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

8128:adrb1
gene id: 8128:adrb1
uniprot id: I3KXX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:hcrt
gene id: 8128:hcrt
uniprot id: C7T453
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Synapse
messages: Vesicle

8128:stx16
gene id: 8128:stx16
uniprot id: I3KSY3
names: Similarity
messages: Belongs to the syntaxin family.

8128:LOC100697454
gene id: 8128:LOC100697454
uniprot id: A0A669CG70
names: Similarity
messages: Belongs to the yippee family.

8128:LOC100706093
gene id: 8128:LOC100706093
uniprot id: A0A669DCK4
names: Similarity
messages: Belongs to the GADD45 family.

8128:mrps30
gene id: 8128:mrps30
uniprot id: A0A669D771
names: Subcellular Location Annotation
messages: Mitochondrion

8128:LOC100710461
gene id: 8128:LOC100710461
uniprot id: I3KKN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8128:LOC100700947
gene id: 8128:LOC100700947
uniprot id: I3K0Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8128:clul1
gene id: 8128:clul1
uniprot id: I3JFL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

8128:thoc5
gene id: 8128:thoc5
uniprot id: I3K7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

8128:LOC100710159
gene id: 8128:LOC100710159
uniprot id: I3J0C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:LOC100708003
gene id: 8128:LOC100708003
uniprot id: A0A669BA31
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8128:ara
gene id: 8128:ara
uniprot id: Q8UWB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:LOC100706611
gene id: 8128:LOC100706611
uniprot id: I3JVC9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100694843
gene id: 8128:LOC100694843
uniprot id: I3KYD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:ss18l1
gene id: 8128:ss18l1
uniprot id: I3KKF4
names: Similarity
messages: Belongs to the SS18 family.

8128:garem1
gene id: 8128:garem1
uniprot id: I3JBC1
names: Similarity
messages: Belongs to the GAREM family.

8128:wdr76
gene id: 8128:wdr76
uniprot id: I3J2W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Interacts with CUL4A and/or CUL4B.
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

8128:LOC100702571
gene id: 8128:LOC100702571
uniprot id: A0A669BWV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:lgr6
gene id: 8128:lgr6
uniprot id: I3K336
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100706089
gene id: 8128:LOC100706089
uniprot id: I3KZQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8128:LOC100694738
gene id: 8128:LOC100694738
uniprot id: I3K7M4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: axon
messages: dendrite

8128:LOC100704922
gene id: 8128:LOC100704922
uniprot id: A0A669EW50
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100704616
gene id: 8128:LOC100704616
uniprot id: A0A669E593
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:LOC100690391
gene id: 8128:LOC100690391
uniprot id: A0A669C073
uniprot id: A0A669CLL9
uniprot id: I3JH44
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100700717
gene id: 8128:LOC100700717
uniprot id: A0A669DIK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

8128:trrap
gene id: 8128:trrap
uniprot id: A0A669EVQ1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. TRA1 subfamily.

8128:LOC100706088
gene id: 8128:LOC100706088
uniprot id: A0A669AY67
names: Subcellular Location Annotation
messages: Nucleus

8128:rft1
gene id: 8128:rft1
uniprot id: I3KS75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

8128:pik3r1
gene id: 8128:pik3r1
uniprot id: A0A669ESG1
uniprot id: A0A669EZC8
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

8128:LOC100692761
gene id: 8128:LOC100692761
uniprot id: A0A669D1R1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100691444
gene id: 8128:LOC100691444
uniprot id: A0A669C4C2
uniprot id: I3JSB0
names: Subcellular Location Annotation
messages: Cytoplasm

8128:map3k10
gene id: 8128:map3k10
uniprot id: I3J711
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

8128:LOC100694427
gene id: 8128:LOC100694427
uniprot id: A0A669DZ50
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:vbp1
gene id: 8128:vbp1
uniprot id: I3JIY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

8128:LOC100698144
gene id: 8128:LOC100698144
uniprot id: A0A669D433
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

8128:sptlc3
gene id: 8128:sptlc3
uniprot id: I3JUS1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

8128:LOC100707278
gene id: 8128:LOC100707278
uniprot id: I3JU45
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:ntng1
gene id: 8128:ntng1
uniprot id: I3JAV6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100696227
gene id: 8128:LOC100696227
uniprot id: I3J8K6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100699616
gene id: 8128:LOC100699616
uniprot id: I3JH21
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100690332
gene id: 8128:LOC100690332
uniprot id: I3JIJ1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:LOC100707650
gene id: 8128:LOC100707650
uniprot id: I3KQL3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100706266
gene id: 8128:LOC100706266
uniprot id: A0A669BGN3
names: Subcellular Location Annotation
messages: cell cortex
messages: cytoskeleton
messages: focal adhesion

8128:LOC100702843
gene id: 8128:LOC100702843
uniprot id: A0A669CJ90
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

8128:LOC100697881
gene id: 8128:LOC100697881
uniprot id: A0A669B0A4
uniprot id: A0A669D2J8
names: Subcellular Location Annotation
messages: ruffle membrane

8128:LOC100705966
gene id: 8128:LOC100705966
uniprot id: A0A669BPM9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8128:LOC100701512
gene id: 8128:LOC100701512
uniprot id: A0A669CJF7
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8128:LOC100699359
gene id: 8128:LOC100699359
uniprot id: A0A669B3P5
uniprot id: I3J316
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:nap1l1
gene id: 8128:nap1l1
uniprot id: A0A669EYW4
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

8128:pan2
gene id: 8128:pan2
uniprot id: A0A669EX83
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

8128:dlk2
gene id: 8128:dlk2
uniprot id: I3JJD2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:cep290
gene id: 8128:cep290
uniprot id: I3J7N0
names: Subcellular Location Annotation
messages: cilium basal body

8128:LOC102081429
gene id: 8128:LOC102081429
uniprot id: I3JJ49
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC102081897
gene id: 8128:LOC102081897
uniprot id: A0A669ELM0
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8128:LOC100707205
gene id: 8128:LOC100707205
uniprot id: A0A669E9V7
names: Subcellular Location Annotation
messages: Membrane

8128:eif3j
gene id: 8128:eif3j
uniprot id: I3JG77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8128:LOC100699674
gene id: 8128:LOC100699674
uniprot id: A0A669CFJ4
uniprot id: A0A669CIS0
uniprot id: A0A669CTT8
uniprot id: A0A669EUY5
uniprot id: I3JW26
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100708044
gene id: 8128:LOC100708044
uniprot id: I3KF83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:LOC100693707
gene id: 8128:LOC100693707
uniprot id: I3JRK5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:atl1
gene id: 8128:atl1
uniprot id: A0A669ESZ9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

8128:trub1
gene id: 8128:trub1
uniprot id: A0A669BC96
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

8128:LOC100692160
gene id: 8128:LOC100692160
uniprot id: A0A669CGV2
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

8128:LOC100707304
gene id: 8128:LOC100707304
uniprot id: I3JJ09
names: Subcellular Location Annotation
messages: Nucleus

8128:spon2
gene id: 8128:spon2
uniprot id: I3IXI2
names: Subcellular Location Annotation
messages: extracellular matrix

8128:LOC102079947
gene id: 8128:LOC102079947
uniprot id: I3KM86
names: Similarity
messages: Belongs to the NLRP family.

8128:LOC100700742
gene id: 8128:LOC100700742
uniprot id: I3KYH9
names: Subcellular Location Annotation
messages: Membrane

8128:xpc
gene id: 8128:xpc
uniprot id: I3IZS0
names: Similarity
messages: Belongs to the XPC family.

8128:tmem115
gene id: 8128:tmem115
uniprot id: A0A669D8C0
names: Subcellular Location Annotation
messages: Membrane

8128:naif1
gene id: 8128:naif1
uniprot id: I3K404
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

8128:pdik1l
gene id: 8128:pdik1l
uniprot id: A0A669EQJ6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100698130
gene id: 8128:LOC100698130
uniprot id: A0A669C4Y2
names: Subcellular Location Annotation
messages: Nucleus

8128:dop1b
gene id: 8128:dop1b
uniprot id: I3KG90
names: Similarity
messages: Belongs to the dopey family.

8128:scube3
gene id: 8128:scube3
uniprot id: I3KJY2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:tmem256
gene id: 8128:tmem256
uniprot id: I3KQ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

8128:LOC109201897
gene id: 8128:LOC109201897
uniprot id: A0A669C646
names: Similarity
messages: Belongs to the globin family.

8128:tm6sf1
gene id: 8128:tm6sf1
uniprot id: I3IUJ9
names: Subcellular Location Annotation
messages: Membrane

8128:asic2
gene id: 8128:asic2
uniprot id: A0A669DWU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100699983
gene id: 8128:LOC100699983
uniprot id: I3KJR8
names: Similarity
messages: Belongs to the TAFA family.

8128:dcaf13
gene id: 8128:dcaf13
uniprot id: I3IU87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

8128:sdhc
gene id: 8128:sdhc
uniprot id: A0A669BB67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

8128:LOC100692353
gene id: 8128:LOC100692353
uniprot id: I3IV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

8128:LOC100703576
gene id: 8128:LOC100703576
uniprot id: A0A669DZF4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100702424
gene id: 8128:LOC100702424
uniprot id: A0A669EPQ5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100699256
gene id: 8128:LOC100699256
uniprot id: A0A669BNM2
uniprot id: A0A669EZB3
uniprot id: I3KJT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8128:usp20
gene id: 8128:usp20
uniprot id: A0A669DN48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

8128:plppr3
gene id: 8128:plppr3
uniprot id: I3JA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:LOC100703879
gene id: 8128:LOC100703879
uniprot id: A0A669CIW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8128:LOC109204578
gene id: 8128:LOC109204578
uniprot id: A0A669EQA5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100705760
gene id: 8128:LOC100705760
uniprot id: A0A669AZY5
uniprot id: A0A669C0H9
uniprot id: A0A669E482
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

8128:LOC100690103
gene id: 8128:LOC100690103
uniprot id: I3KT23
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Homotetramer.

8128:fzd5
gene id: 8128:fzd5
uniprot id: A0A669E751
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100692870
gene id: 8128:LOC100692870
uniprot id: I3KZD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

8128:mul1
gene id: 8128:mul1
uniprot id: I3KIH6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100694895
gene id: 8128:LOC100694895
uniprot id: I3KWJ3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:rtraf
gene id: 8128:rtraf
uniprot id: I3K1N5
names: Similarity
messages: Belongs to the RTRAF family.

8128:mthfs
gene id: 8128:mthfs
uniprot id: I3K8B7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

8128:LOC100697866
gene id: 8128:LOC100697866
uniprot id: A0A669DY04
names: Similarity
messages: Belongs to the TPRG1 family.

8128:kcnc1
gene id: 8128:kcnc1
uniprot id: A0A669BWF1
uniprot id: A0A669DEA8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100703221
gene id: 8128:LOC100703221
uniprot id: I3J305
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100705041
gene id: 8128:LOC100705041
uniprot id: A0A669BLL1
uniprot id: A0A669CK69
uniprot id: I3KFR0
uniprot id: I3KFR1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8128:csrnp3
gene id: 8128:csrnp3
uniprot id: A0A669BD97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8128:LOC100700287
gene id: 8128:LOC100700287
uniprot id: I3KNT1
names: Similarity
messages: Belongs to the heme oxygenase family.

8128:nxph2
gene id: 8128:nxph2
uniprot id: I3J9P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8128:med20
gene id: 8128:med20
uniprot id: I3KRU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8128:LOC100702891
gene id: 8128:LOC100702891
uniprot id: I3J6J6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8128:LOC100695939
gene id: 8128:LOC100695939
uniprot id: I3JCV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

8128:LOC109201896
gene id: 8128:LOC109201896
uniprot id: A0A669CWC7
names: Similarity
messages: Belongs to the globin family.

8128:parp6
gene id: 8128:parp6
uniprot id: I3J3J4
names: Similarity
messages: Belongs to the ARTD/PARP family.

8128:nup210
gene id: 8128:nup210
uniprot id: A0A669D7F8
names: Similarity
messages: Belongs to the NUP210 family.

8128:prlr
gene id: 8128:prlr
uniprot id: Q91513
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

8128:LOC100712554
gene id: 8128:LOC100712554
uniprot id: I3KN04
names: Subcellular Location Annotation
messages: cytoskeleton

8128:tmem242
gene id: 8128:tmem242
uniprot id: A0A669F2N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

8128:LOC100694727
gene id: 8128:LOC100694727
uniprot id: A0A669DUM7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8128:LOC100706765
gene id: 8128:LOC100706765
uniprot id: I3K799
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

8128:smad3
gene id: 8128:smad3
uniprot id: A0A669DLA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100690984
gene id: 8128:LOC100690984
uniprot id: I3K5Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

8128:nploc4
gene id: 8128:nploc4
uniprot id: I3KNQ4
names: Similarity
messages: Belongs to the NPL4 family.

8128:nop16
gene id: 8128:nop16
uniprot id: A0A669DWR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: nucleolus

8128:LOC100707350
gene id: 8128:LOC100707350
uniprot id: I3JDB0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

8128:chl1
gene id: 8128:chl1
uniprot id: A0A669DPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

8128:LOC106096438
gene id: 8128:LOC106096438
uniprot id: A0A669DDE2
uniprot id: A0A669EJJ4
names: Subcellular Location Annotation
messages: Membrane

8128:ube2g2
gene id: 8128:ube2g2
uniprot id: A0A669CH04
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:mbtps1
gene id: 8128:mbtps1
uniprot id: A0A669BKZ2
names: Similarity
messages: Belongs to the peptidase S8 family.

8128:klhl21
gene id: 8128:klhl21
uniprot id: A0A669DHF2
names: Subcellular Location Annotation
messages: spindle

8128:ino80d
gene id: 8128:ino80d
uniprot id: I3JPF6
names: Subcellular Location Annotation
messages: Nucleus

8128:dglucy
gene id: 8128:dglucy
uniprot id: I3K0U3
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

8128:cpsf2
gene id: 8128:cpsf2
uniprot id: I3JEY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

8128:LOC100707443
gene id: 8128:LOC100707443
uniprot id: A0A669EW57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Lysosome
messages: cytosol
messages: extracellular exosome

8128:slc19a1
gene id: 8128:slc19a1
uniprot id: I3IX33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

8128:LOC100700960
gene id: 8128:LOC100700960
uniprot id: I3J4R3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100706164
gene id: 8128:LOC100706164
uniprot id: I3KNV2
names: Similarity
messages: Belongs to the Bcl-2 family.

8128:LOC100698939
gene id: 8128:LOC100698939
uniprot id: I3K347
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100710134
gene id: 8128:LOC100710134
uniprot id: I3JJM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

8128:med14
gene id: 8128:med14
uniprot id: A0A669BX60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8128:tada3
gene id: 8128:tada3
uniprot id: I3KWW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

8128:cenpe
gene id: 8128:cenpe
uniprot id: A0A669EQQ4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:LOC100702684
gene id: 8128:LOC100702684
uniprot id: I3JNN4
names: Similarity
messages: Belongs to the multicopper oxidase family.

8128:LOC100695489
gene id: 8128:LOC100695489
uniprot id: I3JA98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8128:lef1
gene id: 8128:lef1
uniprot id: A0A669BPJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8128:LOC100695224
gene id: 8128:LOC100695224
uniprot id: A0A669CIZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

8128:ssx2ip
gene id: 8128:ssx2ip
uniprot id: I3JK82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

8128:cacng3
gene id: 8128:cacng3
uniprot id: I3KF70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

8128:cers1
gene id: 8128:cers1
uniprot id: I3J0B3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693655
gene id: 8128:LOC100693655
uniprot id: I3JW92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

8128:LOC100695795
gene id: 8128:LOC100695795
uniprot id: I3KUD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

8128:LOC106098411
gene id: 8128:LOC106098411
uniprot id: A0A669DME2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

8128:LOC106098461
gene id: 8128:LOC106098461
uniprot id: A0A669DJS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:LOC100698093
gene id: 8128:LOC100698093
uniprot id: A0A669CKZ8
names: Similarity
messages: Belongs to the ZC3H12 family.

8128:LOC100708175
gene id: 8128:LOC100708175
uniprot id: A0A669D3S9
uniprot id: I3KIQ6
names: Similarity
messages: Belongs to the calponin family.

8128:eya2
gene id: 8128:eya2
uniprot id: I3JIC1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

8128:henmt1
gene id: 8128:henmt1
uniprot id: I3JNS4
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

8128:LOC100705480
gene id: 8128:LOC100705480
uniprot id: I3KXX2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100693369
gene id: 8128:LOC100693369
uniprot id: I3JAE0
names: Similarity
messages: Belongs to the FRAS1 family.

8128:neu3a
gene id: 8128:neu3a
uniprot id: I3JCG9
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8128:mfap2
gene id: 8128:mfap2
uniprot id: I3KRR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

8128:grb2
gene id: 8128:grb2
uniprot id: A0A669EQK9
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

8128:LOC102078638
gene id: 8128:LOC102078638
uniprot id: I3JEY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

8128:pdk3
gene id: 8128:pdk3
uniprot id: I3KAB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8128:rnft1
gene id: 8128:rnft1
uniprot id: I3KLX1
names: Subcellular Location Annotation
messages: Membrane

8128:eif3d
gene id: 8128:eif3d
uniprot id: I3JTK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

8128:LOC100691711
gene id: 8128:LOC100691711
uniprot id: A0A669DXN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC100694496
gene id: 8128:LOC100694496
uniprot id: A0A669C8K7
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100708876
gene id: 8128:LOC100708876
uniprot id: I3JTG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

8128:LOC100709587
gene id: 8128:LOC100709587
uniprot id: I3KSN7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100698355
gene id: 8128:LOC100698355
uniprot id: A0A669E177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

8128:ciapin1
gene id: 8128:ciapin1
uniprot id: A0A669EE21
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

8128:stip1
gene id: 8128:stip1
uniprot id: A0A669BKD9
names: Subcellular Location Annotation
messages: Cytoplasm

8128:fli1
gene id: 8128:fli1
uniprot id: A0A669CRN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:slc6a14
gene id: 8128:slc6a14
uniprot id: A0A669DNA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:edn1
gene id: 8128:edn1
uniprot id: A0A669B3R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

8128:LOC100699861
gene id: 8128:LOC100699861
uniprot id: I3KTM4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:ifitm5
gene id: 8128:ifitm5
uniprot id: A0A669CZT5
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8128:olfml3
gene id: 8128:olfml3
uniprot id: A0A669E486
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OLFML3 family.
messages: Secreted

8128:LOC100705665
gene id: 8128:LOC100705665
uniprot id: I3KH77
names: Subcellular Location Annotation
messages: sarcolemma

8128:LOC100706349
gene id: 8128:LOC100706349
uniprot id: A0A669BT37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:zic3
gene id: 8128:zic3
uniprot id: I3J3G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

8128:fam206a
gene id: 8128:fam206a
uniprot id: I3J193
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

8128:LOC100694323
gene id: 8128:LOC100694323
uniprot id: A0A669C1U9
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:pah
gene id: 8128:pah
uniprot id: D4HNR5
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

8128:LOC100697746
gene id: 8128:LOC100697746
uniprot id: A0A669BXI2
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8128:LOC100710008
gene id: 8128:LOC100710008
uniprot id: I3KDN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

8128:LOC100707815
gene id: 8128:LOC100707815
uniprot id: A0A669CJ29
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:LOC109196662
gene id: 8128:LOC109196662
uniprot id: A0A669ET05
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:six3
gene id: 8128:six3
uniprot id: I3IX46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

8128:dync2li1
gene id: 8128:dync2li1
uniprot id: I3IX02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

8128:sirt2
gene id: 8128:sirt2
uniprot id: I3KII7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.

8128:tdrd5
gene id: 8128:tdrd5
uniprot id: I3K9I6
names: Subcellular Location Annotation
messages: Cytoplasm

8128:atp10d
gene id: 8128:atp10d
uniprot id: I3JZJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8128:hint1
gene id: 8128:hint1
uniprot id: I3IWZ9
names: Similarity
messages: Belongs to the HINT family.

8128:LOC100697817
gene id: 8128:LOC100697817
uniprot id: A0A669EWS7
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

8128:akirin1
gene id: 8128:akirin1
uniprot id: A0A669CDY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

8128:LOC100534482
gene id: 8128:LOC100534482
uniprot id: I3J9P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8128:hspb7
gene id: 8128:hspb7
uniprot id: A0A669EZV5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8128:LOC100711398
gene id: 8128:LOC100711398
uniprot id: I3J7B8
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

8128:LOC100711499
gene id: 8128:LOC100711499
uniprot id: I3JY48
names: Similarity
messages: Belongs to the BRINP family.

8128:LOC100691860
gene id: 8128:LOC100691860
uniprot id: A0A669CXH2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

8128:LOC100711814
gene id: 8128:LOC100711814
uniprot id: I3KYN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

8128:atg13
gene id: 8128:atg13
uniprot id: I3KDF0
uniprot id: I3KDF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

8128:timm10
gene id: 8128:timm10
uniprot id: A0A669FAA6
names: Function
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.

8128:LOC100696407
gene id: 8128:LOC100696407
uniprot id: A0A669E006
names: Subcellular Location Annotation
messages: Membrane

8128:oxct1
gene id: 8128:oxct1
uniprot id: A0A669CZI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

8128:retreg3
gene id: 8128:retreg3
uniprot id: A0A669B8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Membrane

8128:cpne2
gene id: 8128:cpne2
uniprot id: I3JYW0
names: Similarity
messages: Belongs to the copine family.

8128:recql5
gene id: 8128:recql5
uniprot id: I3KTK8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

8128:sgo1
gene id: 8128:sgo1
uniprot id: I3J2D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

8128:ppp2r5a
gene id: 8128:ppp2r5a
uniprot id: A0A669BMZ8
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8128:LOC100706746
gene id: 8128:LOC100706746
uniprot id: I3KMB3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

8128:dhcr7
gene id: 8128:dhcr7
uniprot id: I3J573
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

8128:mturn
gene id: 8128:mturn
uniprot id: A0A669BNY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

8128:LOC100700017
gene id: 8128:LOC100700017
uniprot id: I3J6B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100699288
gene id: 8128:LOC100699288
uniprot id: A0A669CAP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8128:LOC100707822
gene id: 8128:LOC100707822
uniprot id: A0A669CLY3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100694779
gene id: 8128:LOC100694779
uniprot id: A0A669AZ19
uniprot id: I3J9G7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:LOC100710332
gene id: 8128:LOC100710332
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:LOC100696554
gene id: 8128:LOC100696554
uniprot id: A0A669EKR2
names: Similarity
messages: Belongs to the MAGUK family.

8128:dok6
gene id: 8128:dok6
uniprot id: I3KA60
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

8128:stk38l
gene id: 8128:stk38l
uniprot id: A0A669CGP0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100699117
gene id: 8128:LOC100699117
uniprot id: I3JYG0
names: Subcellular Location Annotation
messages: Membrane

8128:sult1a4
gene id: 8128:sult1a4
uniprot id: I3K017
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:LOC100709019
gene id: 8128:LOC100709019
uniprot id: A0A669EEZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

8128:LOC100710841
gene id: 8128:LOC100710841
uniprot id: I3J7G5
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

8128:LOC102082801
gene id: 8128:LOC102082801
uniprot id: A0A669EI67
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

8128:LOC100693254
gene id: 8128:LOC100693254
uniprot id: I3K8A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

8128:LOC102081358
gene id: 8128:LOC102081358
uniprot id: I3JTH4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

8128:LOC100700113
gene id: 8128:LOC100700113
uniprot id: I3KVL0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:ift57
gene id: 8128:ift57
uniprot id: I3K385
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

8128:eif4ebp2
gene id: 8128:eif4ebp2
uniprot id: I3KQB4
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

8128:LOC100698653
gene id: 8128:LOC100698653
uniprot id: A0A669CEF4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100692284
gene id: 8128:LOC100692284
uniprot id: I3K109
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

8128:lhx5
gene id: 8128:lhx5
uniprot id: I3KE66
names: Subcellular Location Annotation
messages: Nucleus

8128:metrnl
gene id: 8128:metrnl
uniprot id: A0A669DVV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the meteorin family.
messages: Secreted

8128:c8a
gene id: 8128:c8a
uniprot id: A0A669BQU2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC102077503
gene id: 8128:LOC102077503
uniprot id: A0A669CB24
uniprot id: I3JUN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

8128:LOC100696193
gene id: 8128:LOC100696193
uniprot id: I3J7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

8128:atg2a
gene id: 8128:atg2a
uniprot id: I3JD01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

8128:LOC100709840
gene id: 8128:LOC100709840
uniprot id: I3JVH7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:stam2
gene id: 8128:stam2
uniprot id: A0A669DI81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

8128:rell1
gene id: 8128:rell1
uniprot id: I3JRZ5
names: Similarity
messages: Belongs to the RELT family.

8128:LOC100700011
gene id: 8128:LOC100700011
uniprot id: I3KQV2
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100706043
gene id: 8128:LOC100706043
uniprot id: A0A669FCD5
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC102082324
gene id: 8128:LOC102082324
uniprot id: A0A669DR32
uniprot id: A0A669E8N4
uniprot id: I3K3T0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:brpf1
gene id: 8128:brpf1
uniprot id: A0A669F8N4
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100697500
gene id: 8128:LOC100697500
uniprot id: I3IX00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:trmt61a
gene id: 8128:trmt61a
uniprot id: A0A669DQS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

8128:lhx1
gene id: 8128:lhx1
uniprot id: I3JW83
names: Subcellular Location Annotation
messages: Nucleus

8128:rpn1
gene id: 8128:rpn1
uniprot id: A0A669DJP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8128:tmem129
gene id: 8128:tmem129
uniprot id: I3KLN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

8128:LOC100707988
gene id: 8128:LOC100707988
uniprot id: A0A669EA80
uniprot id: I3KBL4
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8128:xkr9
gene id: 8128:xkr9
uniprot id: I3K9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:LOC100706809
gene id: 8128:LOC100706809
uniprot id: I3JA53
names: Subcellular Location Annotation
messages: Membrane

8128:smarcad1
gene id: 8128:smarcad1
uniprot id: I3KCW1
names: Subcellular Location Annotation
messages: Chromosome

8128:atxn10
gene id: 8128:atxn10
uniprot id: I3KIV6
names: Function
names: Similarity
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.

8128:LOC100708386
gene id: 8128:LOC100708386
uniprot id: I3J7G7
names: Similarity
messages: Belongs to the peptidase C14A family.

8128:zdhhc2
gene id: 8128:zdhhc2
uniprot id: A0A669CKW4
uniprot id: A0A669EI30
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC100706322
gene id: 8128:LOC100706322
uniprot id: A0A669BEW1
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

8128:LOC100700559
gene id: 8128:LOC100700559
uniprot id: A0A669E0F4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8128:LOC100695148
gene id: 8128:LOC100695148
uniprot id: I3KHZ8
names: Similarity
messages: Belongs to the epsin family.

8128:LOC100692647
gene id: 8128:LOC100692647
uniprot id: I3K8M8
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

8128:fgf16
gene id: 8128:fgf16
uniprot id: H2E8V5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:LOC100693874
gene id: 8128:LOC100693874
uniprot id: A0A669B5H9
uniprot id: A0A669BGK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

8128:LOC100705826
gene id: 8128:LOC100705826
uniprot id: I3KZQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8128:LOC109194179
gene id: 8128:LOC109194179
uniprot id: I3K3J8
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

8128:scarf1
gene id: 8128:scarf1
uniprot id: I3JN41
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100709536
gene id: 8128:LOC100709536
uniprot id: I3JZ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:kcnj5
gene id: 8128:kcnj5
uniprot id: I3JCW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

8128:LOC100704804
gene id: 8128:LOC100704804
uniprot id: A0A669C840
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100701180
gene id: 8128:LOC100701180
uniprot id: A0A669EJT0
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100690163
gene id: 8128:LOC100690163
uniprot id: I3KVC9
names: Similarity
messages: Belongs to the MAGUK family.

8128:LOC100703122
gene id: 8128:LOC100703122
uniprot id: I3KRZ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100704258
gene id: 8128:LOC100704258
uniprot id: I3KZX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

8128:LOC100695535
gene id: 8128:LOC100695535
uniprot id: A0A669F7H6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

8128:LOC100703810
gene id: 8128:LOC100703810
uniprot id: A0A669FBE5
uniprot id: I3JQP9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

8128:LOC100694183
gene id: 8128:LOC100694183
uniprot id: A0A669F500
names: Similarity
messages: Belongs to the actin family.

8128:wnt2
gene id: 8128:wnt2
uniprot id: A0A669DJH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8128:dyrk4
gene id: 8128:dyrk4
uniprot id: A0A669DS46
uniprot id: I3JVQ9
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8128:LOC100708840
gene id: 8128:LOC100708840
uniprot id: A0A669ELD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

8128:LOC100702951
gene id: 8128:LOC100702951
uniprot id: I3JNQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8128:mfsd3
gene id: 8128:mfsd3
uniprot id: I3JXD3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100701617
gene id: 8128:LOC100701617
uniprot id: A0A669EJI1
names: Similarity
messages: Belongs to the FAM102 family.

8128:LOC100693776
gene id: 8128:LOC100693776
uniprot id: I3IZG0
names: Similarity
messages: Belongs to the NipSnap family.

8128:LOC100691522
gene id: 8128:LOC100691522
uniprot id: A0A669CDH4
uniprot id: A0A669CV24
uniprot id: A0A669EPE1
names: Similarity
messages: Belongs to the DOCK family.

8128:kcnh5
gene id: 8128:kcnh5
uniprot id: A0A669CGA4
names: Subcellular Location Annotation
messages: Membrane

8128:prdm2
gene id: 8128:prdm2
uniprot id: I3J7V8
names: Subcellular Location Annotation
messages: Nucleus

8128:ttc39a
gene id: 8128:ttc39a
uniprot id: A0A669CDP6
uniprot id: I3J0V9
names: Similarity
messages: Belongs to the TTC39 family.

8128:LOC100705997
gene id: 8128:LOC100705997
uniprot id: A0A669E1N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

8128:slc8a3
gene id: 8128:slc8a3
uniprot id: A0A669EY91
uniprot id: I3KU69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100694521
gene id: 8128:LOC100694521
uniprot id: A0A669E2I3
uniprot id: A0A669ETU0
uniprot id: I3JKI6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:tada2b
gene id: 8128:tada2b
uniprot id: A0A669BVB8
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100694444
gene id: 8128:LOC100694444
uniprot id: A0A669F7A8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8128:LOC100708706
gene id: 8128:LOC100708706
uniprot id: A0A669DHM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

8128:LOC100705614
gene id: 8128:LOC100705614
uniprot id: I3KPQ8
names: Subcellular Location Annotation
messages: Nucleus

8128:cdc20
gene id: 8128:cdc20
uniprot id: I3JU40
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

8128:LOC100695566
gene id: 8128:LOC100695566
uniprot id: I3K2K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

8128:atp6v1h
gene id: 8128:atp6v1h
uniprot id: A0A669BMJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8128:LOC100712192
gene id: 8128:LOC100712192
uniprot id: I3KMI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:slc12a3
gene id: 8128:slc12a3
uniprot id: I3JX10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8128:bri3
gene id: 8128:bri3
uniprot id: A0A669EFF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRI3 family.
messages: Membrane
messages: perinuclear region

8128:LOC109202971
gene id: 8128:LOC109202971
uniprot id: A0A669DD40
names: Similarity
messages: Belongs to the helicase family.

8128:tsen34
gene id: 8128:tsen34
uniprot id: I3KKW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

8128:nop10
gene id: 8128:nop10
uniprot id: A0A669CQ45
names: Similarity
messages: Belongs to the NOP10 family.

8128:stk40
gene id: 8128:stk40
uniprot id: A0A669E054
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

8128:LOC100691573
gene id: 8128:LOC100691573
uniprot id: A0A669C9A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8128:dapk2
gene id: 8128:dapk2
uniprot id: A0A669BJW0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:barx2
gene id: 8128:barx2
uniprot id: I3JD09
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC102077686
gene id: 8128:LOC102077686
uniprot id: A0A669DBV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

8128:rps15a
gene id: 8128:rps15a
uniprot id: I3KRK7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.

8128:tmem186
gene id: 8128:tmem186
uniprot id: I3KZ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM186 family.
messages: Membrane

8128:kmt2d
gene id: 8128:kmt2d
uniprot id: I3K2C7
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100703038
gene id: 8128:LOC100703038
uniprot id: I3JX12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8128:LOC100697360
gene id: 8128:LOC100697360
uniprot id: I3K6U1
names: Similarity
messages: Belongs to the cytochrome b5 family.

8128:LOC100693120
gene id: 8128:LOC100693120
uniprot id: A0A669EYJ5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:LOC100697260
gene id: 8128:LOC100697260
uniprot id: I3K3H2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:fshb
gene id: 8128:fshb
uniprot id: Q7T2Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

8128:LOC100704294
gene id: 8128:LOC100704294
uniprot id: A0A669F4Z6
uniprot id: I3JLA7
names: Similarity
messages: Belongs to the WD repeat EMAP family.

8128:LOC100699600
gene id: 8128:LOC100699600
uniprot id: A0A669CST9
uniprot id: I3JJB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8128:psmd9
gene id: 8128:psmd9
uniprot id: I3K6A9
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

8128:hm13
gene id: 8128:hm13
uniprot id: A0A669CPM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

8128:LOC100706335
gene id: 8128:LOC100706335
uniprot id: A0A669BF46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8128:LOC100702285
gene id: 8128:LOC100702285
uniprot id: I3J0K8
names: Similarity
messages: Belongs to the PP2C family.

8128:LOC100703331
gene id: 8128:LOC100703331
uniprot id: I3IXB2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:atxn1l
gene id: 8128:atxn1l
uniprot id: I3JEV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

8128:prkar1b
gene id: 8128:prkar1b
uniprot id: A0A669BRE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

8128:nphs1
gene id: 8128:nphs1
uniprot id: I3J3Q6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100707093
gene id: 8128:LOC100707093
uniprot id: I3KZS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

8128:tctn2
gene id: 8128:tctn2
uniprot id: I3K6U3
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

8128:LOC100692985
gene id: 8128:LOC100692985
uniprot id: I3K895
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

8128:nxpe3
gene id: 8128:nxpe3
uniprot id: I3K9Y4
names: Similarity
messages: Belongs to the NXPE family.

8128:LOC100699665
gene id: 8128:LOC100699665
uniprot id: I3KQS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8128:LOC100706691
gene id: 8128:LOC100706691
uniprot id: I3JLI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8128:LOC100693138
gene id: 8128:LOC100693138
uniprot id: I3J297
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC109202221
gene id: 8128:LOC109202221
uniprot id: I3JIC7
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

8128:LOC100534480
gene id: 8128:LOC100534480
uniprot id: I3KCJ8
names: Subcellular Location Annotation
messages: Nucleus

8128:fkbp6
gene id: 8128:fkbp6
uniprot id: I3IWB1
names: Function
names: Similarity
messages: Belongs to the FKBP6 family.
messages: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

8128:mrps21
gene id: 8128:mrps21
uniprot id: A0A669B0R8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

8128:pdk4
gene id: 8128:pdk4
uniprot id: A0A669AXU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8128:pqlc1
gene id: 8128:pqlc1
uniprot id: A0A669BNL1
uniprot id: I3JLF2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100706142
gene id: 8128:LOC100706142
uniprot id: I3KKS4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8128:hsdl2
gene id: 8128:hsdl2
uniprot id: A0A669DTQ9
names: Subcellular Location Annotation
messages: Peroxisome

8128:arhgef28
gene id: 8128:arhgef28
uniprot id: A0A669ECQ2
uniprot id: A0A669EY67
uniprot id: I3JYX2
names: Subcellular Location Annotation
messages: Cytoplasm

8128:mad1l1
gene id: 8128:mad1l1
uniprot id: I3IUB8
names: Similarity
messages: Belongs to the MAD1 family.

8128:LOC102081240
gene id: 8128:LOC102081240
uniprot id: A0A669CS92
names: Subcellular Location Annotation
messages: Nucleus

8128:cplx4
gene id: 8128:cplx4
uniprot id: I3JLE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8128:galm
gene id: 8128:galm
uniprot id: A0A669DBH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldose epimerase family.
messages: Monomer.
messages: Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism.

8128:ubr1
gene id: 8128:ubr1
uniprot id: I3KW88
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

8128:riok2
gene id: 8128:riok2
uniprot id: I3K7Y2
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

8128:myog
gene id: 8128:myog
uniprot id: D2XRC2
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8128:mrps17
gene id: 8128:mrps17
uniprot id: A0A669BZI6
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

8128:slc39a8
gene id: 8128:slc39a8
uniprot id: I3KU46
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693506
gene id: 8128:LOC100693506
uniprot id: A0A669CIR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8128:irx6
gene id: 8128:irx6
uniprot id: A0A669BKI9
names: Subcellular Location Annotation
messages: Nucleus

8128:cep162
gene id: 8128:cep162
uniprot id: I3KI94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP162 family.
messages: centriole

8128:gata6
gene id: 8128:gata6
uniprot id: A0A669CMQ1
names: Subcellular Location Annotation
messages: Nucleus

8128:ak5
gene id: 8128:ak5
uniprot id: I3KPS9
names: Similarity
messages: Belongs to the adenylate kinase family.

8128:tmem244
gene id: 8128:tmem244
uniprot id: I3IWB0
names: Subcellular Location Annotation
messages: Membrane

8128:mcts1
gene id: 8128:mcts1
uniprot id: I3J2X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

8128:LOC100705803
gene id: 8128:LOC100705803
uniprot id: A0A669DHY7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100700643
gene id: 8128:LOC100700643
uniprot id: I3JYC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100700607
gene id: 8128:LOC100700607
uniprot id: A0A669E7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus