8078:adamts15a
gene id: 8078:adamts15a
uniprot id: A0A3Q2NTG8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8078:vps26c
gene id: 8078:vps26c
uniprot id: A0A3Q2PZE5
names: Similarity
messages: Belongs to the VPS26 family.

8078:LOC105927110
gene id: 8078:LOC105927110
uniprot id: A0A147A914
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

8078:tmem131l
gene id: 8078:tmem131l
uniprot id: A0A3Q2NR82
names: Similarity
messages: Belongs to the TMEM131 family.

8078:LOC105933410
gene id: 8078:LOC105933410
uniprot id: A0A3Q2P619
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

8078:thoc7
gene id: 8078:thoc7
uniprot id: A0A3Q2SU37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

8078:pyya
gene id: 8078:pyya
uniprot id: A0A3Q2QYK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

8078:LOC105932957
gene id: 8078:LOC105932957
uniprot id: A0A3Q2Q8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8078:impact
gene id: 8078:impact
uniprot id: A0A3Q2Q4N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

8078:nudt1
gene id: 8078:nudt1
uniprot id: A0A146NAI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

8078:tmem63a
gene id: 8078:tmem63a
uniprot id: A0A146P558
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

8078:foxi2
gene id: 8078:foxi2
uniprot id: A0A3Q2P3V6
names: Subcellular Location Annotation
messages: Nucleus

8078:mfsd5
gene id: 8078:mfsd5
uniprot id: A0A3Q2SN26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

8078:ccdc25
gene id: 8078:ccdc25
uniprot id: A0A3Q2TAW5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

8078:mccc2
gene id: 8078:mccc2
uniprot id: A0A3Q2Q9U7
names: Similarity
messages: Belongs to the AccD/PCCB family.

8078:LOC105916585
gene id: 8078:LOC105916585
uniprot id: A0A3Q2QFN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8078:farsb
gene id: 8078:farsb
uniprot id: A0A3Q2PZZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

8078:rps6kb1b
gene id: 8078:rps6kb1b
uniprot id: A0A146NMU4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8078:unga
gene id: 8078:unga
uniprot id: A0A3Q2TDL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

8078:yipf1
gene id: 8078:yipf1
uniprot id: A0A3Q2QJ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8078:cab39
gene id: 8078:cab39
uniprot id: A0A3Q2UEW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

8078:gtf2e1
gene id: 8078:gtf2e1
uniprot id: A0A146P9B7
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.

8078:taldo1
gene id: 8078:taldo1
uniprot id: A0A146P488
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

8078:LOC105921524
gene id: 8078:LOC105921524
uniprot id: A0A3Q2PX29
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:LOC105935267
gene id: 8078:LOC105935267
uniprot id: A0A3Q2P2S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

8078:hsd17b4
gene id: 8078:hsd17b4
uniprot id: A7BK66
names: Subcellular Location Annotation
messages: Peroxisome

8078:LOC105933370
gene id: 8078:LOC105933370
uniprot id: A0A146ZWW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8078:hyal1
gene id: 8078:hyal1
uniprot id: A0A3Q2QX68
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8078:LOC105916880
gene id: 8078:LOC105916880
uniprot id: A0A147AWW1
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8078:gpm6aa
gene id: 8078:gpm6aa
uniprot id: A0A3Q2P3U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8078:pigw
gene id: 8078:pigw
uniprot id: A0A3Q2P720
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

8078:LOC105929720
gene id: 8078:LOC105929720
uniprot id: A0A3Q2ULB0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8078:mtnr1aa
gene id: 8078:mtnr1aa
uniprot id: A0A3Q2PLZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

8078:bcas2
gene id: 8078:bcas2
uniprot id: A0A3Q2T885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

8078:LOC105934440
gene id: 8078:LOC105934440
uniprot id: A0A3Q2QV15
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

8078:LOC105915827
gene id: 8078:LOC105915827
uniprot id: A0A3Q2PQY8
names: Subcellular Location Annotation
messages: Secreted

8078:LOC105940183
gene id: 8078:LOC105940183
uniprot id: A0A3Q2NS12
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105920557
gene id: 8078:LOC105920557
uniprot id: A0A146TB79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

8078:LOC105917657
gene id: 8078:LOC105917657
uniprot id: A0A146NUV4
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105918766
gene id: 8078:LOC105918766
uniprot id: A0A147ASY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

8078:slc31a2
gene id: 8078:slc31a2
uniprot id: A0A3Q2QTS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

8078:rhot1b
gene id: 8078:rhot1b
uniprot id: A0A146VXH9
uniprot id: A0A146ZXE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

8078:LOC105935918
gene id: 8078:LOC105935918
uniprot id: A0A3Q2PTC3
names: Similarity
messages: Belongs to the cullin family.

8078:rbm10
gene id: 8078:rbm10
uniprot id: A0A3Q2QZY8
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105930302
gene id: 8078:LOC105930302
uniprot id: A0A3Q2PSV1
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

8078:vps26a
gene id: 8078:vps26a
uniprot id: A0A3Q2T699
names: Similarity
messages: Belongs to the VPS26 family.

8078:scamp2l
gene id: 8078:scamp2l
uniprot id: A0A147AZ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8078:riok2
gene id: 8078:riok2
uniprot id: A0A147AA84
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

8078:il17d
gene id: 8078:il17d
uniprot id: A0A3Q2QT25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

8078:extl3
gene id: 8078:extl3
uniprot id: A0A3Q2PKR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8078:zgc:152951
gene id: 8078:zgc:152951
uniprot id: A0A3Q2P7K3
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

8078:slc33a1
gene id: 8078:slc33a1
uniprot id: A0A3Q2Q364
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105929218
gene id: 8078:LOC105929218
uniprot id: A0A3Q2PDW5
names: Similarity
messages: Belongs to the heme oxygenase family.

8078:smad7
gene id: 8078:smad7
uniprot id: A0A3Q2U1L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8078:LOC105938046
gene id: 8078:LOC105938046
uniprot id: A0A146P6L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

8078:aqp3a
gene id: 8078:aqp3a
uniprot id: C1ITJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

8078:LOC105926037
gene id: 8078:LOC105926037
uniprot id: A0A3Q2P071
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

8078:LOC105916244
gene id: 8078:LOC105916244
uniprot id: A0A3Q2QZC7
names: Similarity
messages: Belongs to the SLITRK family.

8078:bcl9l
gene id: 8078:bcl9l
uniprot id: A0A3Q2R0C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

8078:LOC105938845
gene id: 8078:LOC105938845
uniprot id: A0A146ZM80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8078:ttc25
gene id: 8078:ttc25
uniprot id: A0A3Q2PDP8
names: Subcellular Location Annotation
messages: cilium axoneme

8078:slc25a43
gene id: 8078:slc25a43
uniprot id: A0A3Q2PN38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:si:ch211-168f7.5
gene id: 8078:si:ch211-168f7.5
uniprot id: A0A3Q2NS82
names: Similarity
messages: Belongs to the dapper family.

8078:LOC105921460
gene id: 8078:LOC105921460
uniprot id: A0A3Q2NRH2
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8078:zgc:171971
gene id: 8078:zgc:171971
uniprot id: A0A3Q2U0S3
names: Subcellular Location Annotation
messages: Nucleus

8078:pofut2
gene id: 8078:pofut2
uniprot id: A0A3Q2P4I9
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

8078:tgfb1a
gene id: 8078:tgfb1a
uniprot id: A0A3Q2TRI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

8078:coq8b
gene id: 8078:coq8b
uniprot id: A0A3Q2QUJ6
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8078:LOC105933371
gene id: 8078:LOC105933371
uniprot id: A0A146ZWQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8078:enpp4
gene id: 8078:enpp4
uniprot id: A0A3Q2QWQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Cell membrane
messages: Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
messages: Membrane

8078:creb5b
gene id: 8078:creb5b
uniprot id: A0A3Q2PJU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.
messages: Binds to the cAMP response element and activates transcription.
messages: Nucleus

8078:LOC105939685
gene id: 8078:LOC105939685
uniprot id: A0A3Q2SZ67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homomer. Forms heteromers with ACKR4.
messages: Membrane

8078:lpgat1
gene id: 8078:lpgat1
uniprot id: A0A3Q2Q163
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8078:KEG95 p12
gene id: 8078:KEG95_p12
uniprot id: B7U806
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

8078:LOC105937309
gene id: 8078:LOC105937309
uniprot id: A0A3Q2Q528
names: Similarity
messages: Belongs to the globin family.

8078:slc25a22a
gene id: 8078:slc25a22a
uniprot id: A0A3Q2NW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:ugp2b
gene id: 8078:ugp2b
uniprot id: A0A3Q2QLH7
uniprot id: A0A3Q2UBE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

8078:LOC105916616
gene id: 8078:LOC105916616
uniprot id: A0A3Q2QWW4
names: Similarity
messages: Belongs to the beta-catenin family.

8078:rgs7bpb
gene id: 8078:rgs7bpb
uniprot id: A0A3Q2TDM1
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

8078:prkar2ab
gene id: 8078:prkar2ab
uniprot id: A0A3Q2NW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

8078:tbx3a
gene id: 8078:tbx3a
uniprot id: A0A3Q2ULD1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:LOC105931064
gene id: 8078:LOC105931064
uniprot id: A0A147A1E2
names: Subcellular Location Annotation
messages: Nucleus

8078:rps18
gene id: 8078:rps18
uniprot id: A0A3Q2QDP3
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

8078:LOC105921498
gene id: 8078:LOC105921498
uniprot id: A0A3Q2PZ96
names: Subcellular Location Annotation
messages: Membrane

8078:edc3
gene id: 8078:edc3
uniprot id: A0A3Q2P8J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

8078:banf1
gene id: 8078:banf1
uniprot id: A0A3Q2NZA7
names: Subcellular Location Annotation
messages: Nucleus

8078:tmtc2a
gene id: 8078:tmtc2a
uniprot id: A0A3Q2PZZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8078:tpt1
gene id: 8078:tpt1
uniprot id: A0A3Q2P9M9
names: Similarity
messages: Belongs to the TCTP family.

8078:nim1k
gene id: 8078:nim1k
uniprot id: A0A147A0T6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:emc7
gene id: 8078:emc7
uniprot id: A0A3Q2P7U3
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

8078:c3h1orf43
gene id: 8078:c3h1orf43
uniprot id: A0A3Q2QZ15
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

8078:LOC105939963
gene id: 8078:LOC105939963
uniprot id: A0A146ZIH9
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

8078:fam174b
gene id: 8078:fam174b
uniprot id: A0A146Y2C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

8078:LOC105933117
gene id: 8078:LOC105933117
uniprot id: A0A146ZYK3
names: Subcellular Location Annotation
messages: Membrane

8078:hpda
gene id: 8078:hpda
uniprot id: A0A146YM59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

8078:etv7
gene id: 8078:etv7
uniprot id: A0A3Q2P0D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:LOC105927040
gene id: 8078:LOC105927040
uniprot id: A0A146X0R7
names: Similarity
messages: Belongs to the peptidase M14 family.

8078:desi1b
gene id: 8078:desi1b
uniprot id: A0A147A2T8
names: Similarity
messages: Belongs to the DeSI family.

8078:atp6v1c1a
gene id: 8078:atp6v1c1a
uniprot id: A0A146ZXE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

8078:fggy
gene id: 8078:fggy
uniprot id: A0A3Q2PL59
names: Similarity
messages: Belongs to the FGGY kinase family.

8078:syngr3a
gene id: 8078:syngr3a
uniprot id: A0A3Q2Q9M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

8078:LOC105938334
gene id: 8078:LOC105938334
uniprot id: A0A3Q2PLB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Cytoplasm
messages: Nucleus

8078:cyfip2
gene id: 8078:cyfip2
uniprot id: A0A3Q2R1N5
names: Similarity
messages: Belongs to the CYFIP family.

8078:LOC105925436
gene id: 8078:LOC105925436
uniprot id: A0A3Q2P3M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8078:LOC105929272
gene id: 8078:LOC105929272
uniprot id: A0A3Q2QMJ9
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:ptpn2a
gene id: 8078:ptpn2a
uniprot id: A0A146P4K4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

8078:qpctla
gene id: 8078:qpctla
uniprot id: A0A3Q2P1M1
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

8078:tcp11l1
gene id: 8078:tcp11l1
uniprot id: A0A3Q2R237
names: Similarity
messages: Belongs to the TCP11 family.

8078:atp9b
gene id: 8078:atp9b
uniprot id: A0A3Q2PPT9
uniprot id: A0A3Q2PQ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8078:lpl
gene id: 8078:lpl
uniprot id: A0A3Q2Q9B9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

8078:tes
gene id: 8078:tes
uniprot id: A0A3Q2P9C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

8078:mrpl16
gene id: 8078:mrpl16
uniprot id: A0A3Q2PKV0
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

8078:tmtc4
gene id: 8078:tmtc4
uniprot id: A0A3Q2PA57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8078:taf13
gene id: 8078:taf13
uniprot id: A0A3Q2PH89
names: Subcellular Location Annotation
messages: Nucleus

8078:arg1
gene id: 8078:arg1
uniprot id: A0A3Q2PVT5
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

8078:LOC105928174
gene id: 8078:LOC105928174
uniprot id: A0A146WUY6
names: Similarity
messages: Belongs to the peptidase M67C family.

8078:sumo2a
gene id: 8078:sumo2a
uniprot id: A0A3Q2QAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8078:pah
gene id: 8078:pah
uniprot id: A0A3Q2NTL3
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

8078:mindy1
gene id: 8078:mindy1
uniprot id: A0A3Q2PP02
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

8078:ccdc58
gene id: 8078:ccdc58
uniprot id: A0A146ZLI7
names: Similarity
messages: Belongs to the MIX23 family.

8078:birc2
gene id: 8078:birc2
uniprot id: A0A3Q2QW44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

8078:LOC105935246
gene id: 8078:LOC105935246
uniprot id: A0A3Q2QQV0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-97 and Arg-100) that bind to malonylated and succinylated substrates and define the specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
messages: Nucleus
messages: cytosol

8078:lsm14aa
gene id: 8078:lsm14aa
uniprot id: A0A3Q2PWU1
names: Similarity
messages: Belongs to the LSM14 family.

8078:LOC105929538
gene id: 8078:LOC105929538
uniprot id: A0A3Q2NMK5
names: Similarity
messages: Belongs to the fl(2)d family.

8078:stk17al
gene id: 8078:stk17al
uniprot id: A0A3Q2PCG9
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:hdac3
gene id: 8078:hdac3
uniprot id: A0A3Q2TU68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

8078:eml1
gene id: 8078:eml1
uniprot id: A0A146WT98
names: Similarity
messages: Belongs to the WD repeat EMAP family.

8078:LOC105931183
gene id: 8078:LOC105931183
uniprot id: A0A146PN06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

8078:dipk1b
gene id: 8078:dipk1b
uniprot id: A0A147A5V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

8078:LOC105925186
gene id: 8078:LOC105925186
uniprot id: A0A3Q2TG62
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8078:tcn2
gene id: 8078:tcn2
uniprot id: A0A3Q2QTF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

8078:dusp7
gene id: 8078:dusp7
uniprot id: A0A146P5E5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8078:LOC105925809
gene id: 8078:LOC105925809
uniprot id: A0A147B647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8078:LOC105930249
gene id: 8078:LOC105930249
uniprot id: A0A3Q2PUY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:hnrpkl
gene id: 8078:hnrpkl
uniprot id: A0A3Q2R458
names: Subcellular Location Annotation
messages: nucleoplasm

8078:csnk1g1
gene id: 8078:csnk1g1
uniprot id: A0A146YND5
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

8078:dlx1a
gene id: 8078:dlx1a
uniprot id: A0A146XTC8
names: Subcellular Location Annotation
messages: Nucleus

8078:cachd1
gene id: 8078:cachd1
uniprot id: A0A3Q2Q5V3
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

8078:dedd
gene id: 8078:dedd
uniprot id: A0A3Q2P412
names: Subcellular Location Annotation
messages: nucleolus

8078:ptenb
gene id: 8078:ptenb
uniprot id: A0A147AZ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

8078:nle1
gene id: 8078:nle1
uniprot id: A0A3Q2QUZ6
names: Subcellular Location Annotation
messages: nucleolus

8078:psmb13a
gene id: 8078:psmb13a
uniprot id: A0A3Q2T681
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8078:crppa
gene id: 8078:crppa
uniprot id: A0A3Q2QGH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Homodimer.
messages: cytosol

8078:LOC105940374
gene id: 8078:LOC105940374
uniprot id: A0A147B0E2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:minpp1b
gene id: 8078:minpp1b
uniprot id: A0A3Q2PXH0
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

8078:fam118b
gene id: 8078:fam118b
uniprot id: A9CQJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM118 family.
messages: Cajal body
messages: May play a role in Cajal bodies formation.

8078:LOC105936085
gene id: 8078:LOC105936085
uniprot id: A0A3Q2PD72
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

8078:baiap2a
gene id: 8078:baiap2a
uniprot id: A0A146W7B9
uniprot id: A0A3Q2PGN7
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

8078:LOC105925263
gene id: 8078:LOC105925263
uniprot id: A0A3Q2PNJ7
names: Subcellular Location Annotation
messages: Membrane

8078:tgif1
gene id: 8078:tgif1
uniprot id: A0A147AUD2
names: Subcellular Location Annotation
messages: Nucleus

8078:cfap45
gene id: 8078:cfap45
uniprot id: A0A3Q2PM25
names: Similarity
messages: Belongs to the CFAP45 family.

8078:pparaa
gene id: 8078:pparaa
uniprot id: A0A3Q2P6Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:LOC105928645
gene id: 8078:LOC105928645
uniprot id: A0A146WPA3
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

8078:si:dkey-246i14.3
gene id: 8078:si:dkey-246i14.3
uniprot id: A0A147A762
uniprot id: A0A3Q2PXV5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105933394
gene id: 8078:LOC105933394
uniprot id: A0A3Q2P9U8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105933637
gene id: 8078:LOC105933637
uniprot id: A0A3Q2QZZ6
names: Similarity
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.

8078:zgc:101785
gene id: 8078:zgc:101785
uniprot id: A0A3Q2PW66
names: Similarity
messages: Belongs to the annexin family.

8078:LOC105920285
gene id: 8078:LOC105920285
uniprot id: A0A146Z7X7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:cited4b
gene id: 8078:cited4b
uniprot id: A0A3Q2PD65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

8078:pnpo
gene id: 8078:pnpo
uniprot id: A0A146ZQW7
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

8078:si:ch1073-459j12.1
gene id: 8078:si:ch1073-459j12.1
uniprot id: A0A3Q2P9A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

8078:LOC105933013
gene id: 8078:LOC105933013
uniprot id: A0A3Q2Q688
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.

8078:LOC105915822
gene id: 8078:LOC105915822
uniprot id: A0A146P913
names: Similarity
messages: Belongs to the SMARCD family.

8078:slc8a3
gene id: 8078:slc8a3
uniprot id: A0A3Q2NW66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

8078:LOC105919214
gene id: 8078:LOC105919214
uniprot id: A0A146RX85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

8078:LOC105926900
gene id: 8078:LOC105926900
uniprot id: A0A3Q2PRJ2
uniprot id: A0A3Q2THL2
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

8078:glyctk
gene id: 8078:glyctk
uniprot id: A0A3Q2ULX1
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

8078:sf1
gene id: 8078:sf1
uniprot id: A0A3Q2R2D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

8078:rp2
gene id: 8078:rp2
uniprot id: A0A3Q2QKW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

8078:rpl12
gene id: 8078:rpl12
uniprot id: A0A3Q2T665
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

8078:LOC105930324
gene id: 8078:LOC105930324
uniprot id: A0A3Q2QN28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Homodimer.

8078:fam110a
gene id: 8078:fam110a
uniprot id: A0A3Q2Q3E9
names: Similarity
messages: Belongs to the FAM110 family.

8078:sypb
gene id: 8078:sypb
uniprot id: A0A3Q2Q2X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8078:skor2
gene id: 8078:skor2
uniprot id: A0A147A4T4
names: Similarity
messages: Belongs to the SKI family.

8078:cdca9
gene id: 8078:cdca9
uniprot id: A0A3Q2R0E4
names: Similarity
messages: Belongs to the borealin family.

8078:p3h2
gene id: 8078:p3h2
uniprot id: A0A3Q2SZA0
names: Similarity
messages: Belongs to the leprecan family.

8078:LOC105937937
gene id: 8078:LOC105937937
uniprot id: A0A3Q2P8F0
names: Subcellular Location Annotation
messages: Nucleus
messages: Vesicle
messages: clathrin-coated pit
messages: clathrin-coated vesicle

8078:irx7
gene id: 8078:irx7
uniprot id: A0A3Q2Q7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8078:LOC105933168
gene id: 8078:LOC105933168
uniprot id: A0A3Q2QV09
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cilium basal body

8078:pdcd5
gene id: 8078:pdcd5
uniprot id: A0A3Q2UP95
names: Similarity
messages: Belongs to the PDCD5 family.

8078:LOC105920787
gene id: 8078:LOC105920787
uniprot id: A0A3Q2QCQ9
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8078:atg4da
gene id: 8078:atg4da
uniprot id: A0A3Q2QFG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8078:LOC105932901
gene id: 8078:LOC105932901
uniprot id: A0A3Q2NX00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

8078:crhr1
gene id: 8078:crhr1
uniprot id: A0A3Q2PBS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

8078:slu7
gene id: 8078:slu7
uniprot id: A0A3Q2PFF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

8078:LOC105924954
gene id: 8078:LOC105924954
uniprot id: A0A3Q2TGQ4
names: Similarity
messages: Belongs to the ATG8 family.

8078:slc25a44a
gene id: 8078:slc25a44a
uniprot id: A0A3Q2PT05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:tec
gene id: 8078:tec
uniprot id: A0A3Q2NQ06
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8078:LOC105936646
gene id: 8078:LOC105936646
uniprot id: A0A3Q2P657
names: Similarity
messages: Belongs to the S-100 family.

8078:cx52.6
gene id: 8078:cx52.6
uniprot id: A0A3Q2QHV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8078:aadac
gene id: 8078:aadac
uniprot id: A0A3Q2QV02
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

8078:eif4ebp1
gene id: 8078:eif4ebp1
uniprot id: A0A3Q2TG43
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

8078:gna13b
gene id: 8078:gna13b
uniprot id: A0A146V978
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

8078:ptger1c
gene id: 8078:ptger1c
uniprot id: A0A3Q2PKF4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:LOC105930243
gene id: 8078:LOC105930243
uniprot id: A0A3Q2PV92
names: Similarity
messages: Belongs to the peptidase C14A family.

8078:LOC105931721
gene id: 8078:LOC105931721
uniprot id: A0A3Q2QE54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

8078:ebna1bp2
gene id: 8078:ebna1bp2
uniprot id: A0A146VDE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: Required for the processing of the 27S pre-rRNA.
messages: nucleolus

8078:trim2a
gene id: 8078:trim2a
uniprot id: A0A3Q2TYR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

8078:keap1b
gene id: 8078:keap1b
uniprot id: A0A3Q2QGP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KEAP1 family.
messages: Cytoplasm
messages: Nucleus

8078:ints7
gene id: 8078:ints7
uniprot id: A0A3Q2Q2T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus

8078:tmtc2b
gene id: 8078:tmtc2b
uniprot id: A0A147AB39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8078:cdkn2aipnl
gene id: 8078:cdkn2aipnl
uniprot id: A0A3Q2R044
names: Similarity
messages: Belongs to the CARF family.

8078:atp7b
gene id: 8078:atp7b
uniprot id: A0A3Q2QTJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

8078:gdf3
gene id: 8078:gdf3
uniprot id: A0A3Q2PJK7
names: Similarity
messages: Belongs to the TGF-beta family.

8078:KEG95 p08
gene id: 8078:KEG95_p08
uniprot id: B7U7V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

8078:lrrc8aa
gene id: 8078:lrrc8aa
uniprot id: A0A146SGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8078:LOC105931421
gene id: 8078:LOC105931421
uniprot id: A0A146P6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8078:ltb4r2b
gene id: 8078:ltb4r2b
uniprot id: A0A3Q2U231
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:LOC105921308
gene id: 8078:LOC105921308
uniprot id: A0A3Q2P2A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

8078:zgc:77849
gene id: 8078:zgc:77849
uniprot id: A0A3Q2PFN0
names: Similarity
messages: Belongs to the TAPR1 family.

8078:lrig3
gene id: 8078:lrig3
uniprot id: A0A3Q2QUR5
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105916404
gene id: 8078:LOC105916404
uniprot id: B1B605
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:adra2b
gene id: 8078:adra2b
uniprot id: A0A3Q2TSF1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:ube2al
gene id: 8078:ube2al
uniprot id: Q8JHF8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:fscn2b
gene id: 8078:fscn2b
uniprot id: A0A146ZS62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

8078:rpl8
gene id: 8078:rpl8
uniprot id: A0A3Q2T3N2
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

8078:LOC105937542
gene id: 8078:LOC105937542
uniprot id: A0A3Q2NMC4
names: Similarity
messages: Belongs to the beta-catenin family.

8078:adora1b
gene id: 8078:adora1b
uniprot id: A0A3Q2NX84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

8078:zwilch
gene id: 8078:zwilch
uniprot id: A0A3Q2NY69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

8078:sardh
gene id: 8078:sardh
uniprot id: A0A3Q2PCC1
names: Similarity
messages: Belongs to the GcvT family.

8078:notum1b
gene id: 8078:notum1b
uniprot id: A0A3Q2PUA8
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

8078:myo1f
gene id: 8078:myo1f
uniprot id: A0A146ZL72
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8078:LOC105921140
gene id: 8078:LOC105921140
uniprot id: A0A3Q2PHM1
names: Subcellular Location Annotation
messages: Membrane

8078:ppfia1
gene id: 8078:ppfia1
uniprot id: A0A3Q2PRP2
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

8078:stam2
gene id: 8078:stam2
uniprot id: A0A3Q2QS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

8078:ddo
gene id: 8078:ddo
uniprot id: A0A146W5P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

8078:aoc1
gene id: 8078:aoc1
uniprot id: A0A146ZZ13
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

8078:elovl8b
gene id: 8078:elovl8b
uniprot id: A0A146WWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

8078:chmp4c
gene id: 8078:chmp4c
uniprot id: A0A3Q2TCJ2
names: Similarity
messages: Belongs to the SNF7 family.

8078:sde2
gene id: 8078:sde2
uniprot id: A0A3Q2P065
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Nucleus

8078:surf6
gene id: 8078:surf6
uniprot id: A0A3Q2TYQ6
names: Similarity
messages: Belongs to the SURF6 family.

8078:parvaa
gene id: 8078:parvaa
uniprot id: A0A146MZ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

8078:dio1
gene id: 8078:dio1
uniprot id: Q804E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the iodothyronine deiodinase family.
messages: Endoplasmic reticulum membrane
messages: Expressed in liver.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).

8078:rer1
gene id: 8078:rer1
uniprot id: A0A146NN51
uniprot id: A0A3Q2NRA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

8078:LOC105927082
gene id: 8078:LOC105927082
uniprot id: A0A3Q2U4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

8078:mrpl27
gene id: 8078:mrpl27
uniprot id: A0A3Q2QFB1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

8078:rpsa
gene id: 8078:rpsa
uniprot id: A0A3Q2T3T1
names: Caution
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

8078:tnksa
gene id: 8078:tnksa
uniprot id: A0A147A1E8
names: Similarity
messages: Belongs to the ARTD/PARP family.

8078:tmem17
gene id: 8078:tmem17
uniprot id: A0A3Q2P7Z1
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105931970
gene id: 8078:LOC105931970
uniprot id: A0A3Q2PTE7
names: Function
messages: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.

8078:ndufv2
gene id: 8078:ndufv2
uniprot id: A0A146P565
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

8078:slc25a28
gene id: 8078:slc25a28
uniprot id: A0A146ZL33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:rraga
gene id: 8078:rraga
uniprot id: A0A3Q2Q5L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

8078:rpl9
gene id: 8078:rpl9
uniprot id: A0A3Q2T1V7
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

8078:fgf20b
gene id: 8078:fgf20b
uniprot id: A0A3Q2PMY9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8078:fzr1a
gene id: 8078:fzr1a
uniprot id: A0A146P7F2
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

8078:xgb
gene id: 8078:xgb
uniprot id: A0A147AXV7
names: Similarity
messages: Belongs to the globin family.

8078:LOC105925205
gene id: 8078:LOC105925205
uniprot id: A0A147AD79
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytosol

8078:LOC105935500
gene id: 8078:LOC105935500
uniprot id: A0A3Q2QIQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COA8 family.
messages: Mitochondrion inner membrane

8078:slc31a1
gene id: 8078:slc31a1
uniprot id: A0A3Q2SWT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

8078:akirin2
gene id: 8078:akirin2
uniprot id: A0A146ZL09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

8078:LOC105929450
gene id: 8078:LOC105929450
uniprot id: A0A3Q2Q4C3
names: Similarity
messages: Belongs to the HINT family.

8078:LOC105939773
gene id: 8078:LOC105939773
uniprot id: A0A3Q2NSW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane

8078:LOC105924743
gene id: 8078:LOC105924743
uniprot id: A0A3Q2PC22
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:itpka
gene id: 8078:itpka
uniprot id: A0A3Q2QE01
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8078:trappc6bl
gene id: 8078:trappc6bl
uniprot id: A0A147AP82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

8078:pigu
gene id: 8078:pigu
uniprot id: A0A3Q2QWK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:kcnab1a
gene id: 8078:kcnab1a
uniprot id: A0A3Q2Q3J0
uniprot id: A0A3Q2Q5B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8078:kpna2
gene id: 8078:kpna2
uniprot id: A0A146WGP5
names: Similarity
messages: Belongs to the importin alpha family.

8078:nme5
gene id: 8078:nme5
uniprot id: A0A3Q2QND1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8078:gdf6a
gene id: 8078:gdf6a
uniprot id: A0A3Q2U8F8
names: Similarity
messages: Belongs to the TGF-beta family.

8078:bet1l
gene id: 8078:bet1l
uniprot id: A0A3Q2P7B5
names: Subcellular Location Annotation
messages: Membrane

8078:thrb
gene id: 8078:thrb
uniprot id: A0A3Q2ULY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8078:pa2g4b
gene id: 8078:pa2g4b
uniprot id: A0A146P612
names: Similarity
messages: Belongs to the peptidase M24 family.

8078:sf3b6
gene id: 8078:sf3b6
uniprot id: A0A3Q2R2H4
names: Subcellular Location Annotation
messages: Nucleus

8078:ano8b
gene id: 8078:ano8b
uniprot id: A0A3Q2Q1I3
uniprot id: A0A3Q2R1Q4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105923910
gene id: 8078:LOC105923910
uniprot id: A0A3Q2UF67
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:vkorc1
gene id: 8078:vkorc1
uniprot id: A0A3Q2Q8X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:LOC105928872
gene id: 8078:LOC105928872
uniprot id: A0A3Q2Q4D3
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:vac14
gene id: 8078:vac14
uniprot id: A0A3Q2PMP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAC14 family.
messages: Endosome membrane
messages: Microsome membrane

8078:tshz3a
gene id: 8078:tshz3a
uniprot id: A0A3Q2QL41
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

8078:klc2
gene id: 8078:klc2
uniprot id: A0A3Q2UP05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8078:tfpia
gene id: 8078:tfpia
uniprot id: A0A3Q2PHQ1
names: Subcellular Location Annotation
messages: Secreted

8078:LOC105938731
gene id: 8078:LOC105938731
uniprot id: A0A3Q2R0V6
names: Similarity
messages: Belongs to the DDIT4 family.

8078:abhd3
gene id: 8078:abhd3
uniprot id: A0A147B4I9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

8078:LOC105923069
gene id: 8078:LOC105923069
uniprot id: Q8AY58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

8078:LOC105925664
gene id: 8078:LOC105925664
uniprot id: A0A3Q2TL16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

8078:ela3l
gene id: 8078:ela3l
uniprot id: A0A3Q2QVX2
names: Subcellular Location Annotation
messages: extracellular space

8078:fundc1
gene id: 8078:fundc1
uniprot id: A0A146ZT26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

8078:LOC105928602
gene id: 8078:LOC105928602
uniprot id: A0A3Q2SUH0
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

8078:gpr155b
gene id: 8078:gpr155b
uniprot id: A0A3Q2UBW4
names: Subcellular Location Annotation
messages: Membrane

8078:nkiras2
gene id: 8078:nkiras2
uniprot id: A0A3Q2QLE0
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

8078:LOC105937293
gene id: 8078:LOC105937293
uniprot id: A0A3Q2NPE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

8078:dtx2
gene id: 8078:dtx2
uniprot id: A0A3Q2P078
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8078:tspan7b
gene id: 8078:tspan7b
uniprot id: A0A3Q2PCJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:nmur3
gene id: 8078:nmur3
uniprot id: A0A3Q2PFJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

8078:snx33
gene id: 8078:snx33
uniprot id: A0A3Q2QWM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8078:tmem167b
gene id: 8078:tmem167b
uniprot id: A0A3Q2P043
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:alpi.1
gene id: 8078:alpi.1
uniprot id: A0A146ZXB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline phosphatase family.
messages: Cell membrane
messages: Membrane

8078:plpp4
gene id: 8078:plpp4
uniprot id: A0A3Q2PU74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8078:eif1axb
gene id: 8078:eif1axb
uniprot id: A0A146NDG5
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

8078:LOC105925621
gene id: 8078:LOC105925621
uniprot id: A0A3Q2PXB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm

8078:yme1l1b
gene id: 8078:yme1l1b
uniprot id: A0A146P5X4
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

8078:KEG95 p13
gene id: 8078:KEG95_p13
uniprot id: B7U805
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

8078:tmem38a
gene id: 8078:tmem38a
uniprot id: A0A3Q2P8U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

8078:LOC105932302
gene id: 8078:LOC105932302
uniprot id: A0A3Q2SS72
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8078:wee1
gene id: 8078:wee1
uniprot id: A0A146NSJ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

8078:ribc1
gene id: 8078:ribc1
uniprot id: A0A147A5H7
names: Similarity
messages: Belongs to the RIB43A family.

8078:adgrl4
gene id: 8078:adgrl4
uniprot id: A0A3Q2NUV3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:zbtb8os
gene id: 8078:zbtb8os
uniprot id: A0A3Q2PQH4
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

8078:foxa2
gene id: 8078:foxa2
uniprot id: A0A3Q2P4G7
names: Subcellular Location Annotation
messages: Nucleus

8078:ints14
gene id: 8078:ints14
uniprot id: A0A146NEP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

8078:f13a1b
gene id: 8078:f13a1b
uniprot id: A0A3Q2PYI7
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8078:p2rx4b
gene id: 8078:p2rx4b
uniprot id: A0A3Q2QB29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8078:sept10
gene id: 8078:sept10
uniprot id: A0A3Q2QTZ0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8078:gusb
gene id: 8078:gusb
uniprot id: A0A146P5C5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homotetramer.
messages: Inhibited by L-aspartic acid.
messages: Lysosome
messages: Plays an important role in the degradation of dermatan and keratan sulfates.

8078:matk
gene id: 8078:matk
uniprot id: A0A146ZQY1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8078:LOC105935548
gene id: 8078:LOC105935548
uniprot id: A0A3Q2P9N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8078:ppib
gene id: 8078:ppib
uniprot id: A0A3Q2PTP4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8078:uxs1
gene id: 8078:uxs1
uniprot id: A0A3Q2QPN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

8078:serpini1
gene id: 8078:serpini1
uniprot id: A0A3Q2Q4S4
names: Similarity
messages: Belongs to the serpin family.

8078:crabp2b
gene id: 8078:crabp2b
uniprot id: A0A146VP21
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8078:ilf3b
gene id: 8078:ilf3b
uniprot id: A0A146WJ95
uniprot id: A0A3Q2QI25
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8078:LOC105915937
gene id: 8078:LOC105915937
uniprot id: A0A3Q2QPX0
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

8078:dhtkd1
gene id: 8078:dhtkd1
uniprot id: A0A146PEE1
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

8078:porb
gene id: 8078:porb
uniprot id: A0A146P438
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

8078:LOC105927731
gene id: 8078:LOC105927731
uniprot id: A0A3Q2NVH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

8078:LOC105936367
gene id: 8078:LOC105936367
uniprot id: A0A3Q2Q6X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8078:ube2s
gene id: 8078:ube2s
uniprot id: A0A3Q2QSD1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:eaf1
gene id: 8078:eaf1
uniprot id: A0A147AU01
names: Similarity
messages: Belongs to the EAF family.

8078:stx3a
gene id: 8078:stx3a
uniprot id: A0A3Q2QR60
names: Similarity
messages: Belongs to the syntaxin family.

8078:LOC105939107
gene id: 8078:LOC105939107
uniprot id: A0A3Q2T0Y4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:snx11
gene id: 8078:snx11
uniprot id: A0A3Q2NZF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

8078:fut8b
gene id: 8078:fut8b
uniprot id: A0A3Q2ST03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

8078:smu1a
gene id: 8078:smu1a
uniprot id: A0A3Q2PIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

8078:c1d
gene id: 8078:c1d
uniprot id: A0A3Q2PAA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Nucleus
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

8078:lhfpl2a
gene id: 8078:lhfpl2a
uniprot id: A0A3Q2QLY1
names: Subcellular Location Annotation
messages: Membrane

8078:ctnnal1
gene id: 8078:ctnnal1
uniprot id: A0A3Q2NME6
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

8078:LOC105917072
gene id: 8078:LOC105917072
uniprot id: A0A3Q2PB62
names: Similarity
messages: Belongs to the cytochrome b5 family.

8078:pvalb7
gene id: 8078:pvalb7
uniprot id: A0A3Q2UAA7
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8078:tram2
gene id: 8078:tram2
uniprot id: A0A3Q2Q460
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

8078:stim2a
gene id: 8078:stim2a
uniprot id: A0A146P3H2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:LOC105937679
gene id: 8078:LOC105937679
uniprot id: A0A146ZN34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8078:srp9
gene id: 8078:srp9
uniprot id: A0A3Q2T6Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

8078:pvalb9
gene id: 8078:pvalb9
uniprot id: A0A147AZJ0
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8078:lacc1
gene id: 8078:lacc1
uniprot id: A0A146ZJ38
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

8078:coq8ab
gene id: 8078:coq8ab
uniprot id: A0A3Q2NU13
uniprot id: A0A3Q2Q9L5
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8078:gars1
gene id: 8078:gars1
uniprot id: A0A146P442
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

8078:coq8aa
gene id: 8078:coq8aa
uniprot id: A0A3Q2Q0G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane
messages: Mitochondrion

8078:xiap
gene id: 8078:xiap
uniprot id: A0A3Q2NQI4
names: Similarity
messages: Belongs to the IAP family.

8078:lrrc8ab
gene id: 8078:lrrc8ab
uniprot id: A0A3Q2R087
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8078:LOC105930975
gene id: 8078:LOC105930975
uniprot id: A0A3Q2PC21
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:zgc:158803
gene id: 8078:zgc:158803
uniprot id: A0A3Q2P3C5
names: Similarity
messages: Belongs to the Luc7 family.

8078:LOC105918202
gene id: 8078:LOC105918202
uniprot id: A0A146Z8V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8078:rpn1
gene id: 8078:rpn1
uniprot id: A0A146X5B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8078:dipk1c
gene id: 8078:dipk1c
uniprot id: A0A3Q2QMC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

8078:cacul1
gene id: 8078:cacul1
uniprot id: A0A3Q2P376
names: Similarity
messages: Belongs to the cullin family.

8078:kdm5ba
gene id: 8078:kdm5ba
uniprot id: A0A3Q2P3J0
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

8078:LOC105936166
gene id: 8078:LOC105936166
uniprot id: A0A3Q2U798
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8078:psme3
gene id: 8078:psme3
uniprot id: A0A3Q2QL54
names: Similarity
messages: Belongs to the PA28 family.

8078:ppat
gene id: 8078:ppat
uniprot id: A0A3Q2NNE4
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

8078:LOC105932435
gene id: 8078:LOC105932435
uniprot id: A0A146ZYF1
names: Subcellular Location Annotation
messages: extracellular space

8078:kcnj8
gene id: 8078:kcnj8
uniprot id: A0A3Q2P9Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8078:stxbp1a
gene id: 8078:stxbp1a
uniprot id: A0A3Q2QRH5
uniprot id: A0A3Q2QTU5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8078:rflna
gene id: 8078:rflna
uniprot id: A0A147A5T6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

8078:impdh2
gene id: 8078:impdh2
uniprot id: A0A3Q2PSF0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

8078:alg10
gene id: 8078:alg10
uniprot id: A0A3Q2SSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Membrane

8078:sost
gene id: 8078:sost
uniprot id: A0A146ZP03
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the sclerostin family.
messages: Interacts with LRP4 (via the extracellular domain); the interaction facilitates the inhibition of Wnt signaling. Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling. Interacts with LRP6.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

8078:med4
gene id: 8078:med4
uniprot id: A0A146UUC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8078:LOC105932610
gene id: 8078:LOC105932610
uniprot id: A0A3Q2TF01
names: Similarity
messages: Belongs to the SH2B adapter family.

8078:pdss1
gene id: 8078:pdss1
uniprot id: A0A3Q2Q693
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8078:spg7
gene id: 8078:spg7
uniprot id: A0A146NDZ4
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

8078:LOC105917704
gene id: 8078:LOC105917704
uniprot id: A0A3Q2P9V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8078:LOC105920525
gene id: 8078:LOC105920525
uniprot id: A0A3Q2T957
names: Subcellular Location Annotation
messages: Membrane

8078:atp2a3
gene id: 8078:atp2a3
uniprot id: A0A3Q2T9V8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8078:casq1a
gene id: 8078:casq1a
uniprot id: A0A3Q2QUP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

8078:grin2ca
gene id: 8078:grin2ca
uniprot id: A0A154MI97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

8078:ogna
gene id: 8078:ogna
uniprot id: A0A147AZ25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
messages: extracellular matrix

8078:LOC105929867
gene id: 8078:LOC105929867
uniprot id: A0A3Q2T7U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

8078:LOC105939596
gene id: 8078:LOC105939596
uniprot id: A0A3Q2QIY5
names: Similarity
messages: Belongs to the CCSER family.

8078:rps27.1
gene id: 8078:rps27.1
uniprot id: A0A3Q2QN23
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

8078:si:ch211-232b12.5
gene id: 8078:si:ch211-232b12.5
uniprot id: A0A3Q2NRG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8078:ins
gene id: 8078:ins
uniprot id: A0A3Q2SXP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

8078:slc5a3b
gene id: 8078:slc5a3b
uniprot id: A0A146Q070
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8078:zgc:112052
gene id: 8078:zgc:112052
uniprot id: A0A3Q2PDM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

8078:gpr4
gene id: 8078:gpr4
uniprot id: A0A3Q2TPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:ndufa3
gene id: 8078:ndufa3
uniprot id: A0A146WT02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA3 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane
messages: Mitochondrion inner membrane

8078:lbh
gene id: 8078:lbh
uniprot id: A0A3Q2UMT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus

8078:rhpn2
gene id: 8078:rhpn2
uniprot id: A0A146ZWF9
names: Similarity
messages: Belongs to the RHPN family.

8078:lft1
gene id: 8078:lft1
uniprot id: A0A146ZPF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

8078:LOC105936423
gene id: 8078:LOC105936423
uniprot id: A0A3Q2NPU1
names: Similarity
messages: Belongs to the SNF7 family.

8078:sgcg
gene id: 8078:sgcg
uniprot id: A0A3Q2UI88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: cytoskeleton
messages: sarcolemma

8078:chrdl2
gene id: 8078:chrdl2
uniprot id: A0A3Q2QPD3
names: Subcellular Location Annotation
messages: Secreted

8078:ap1s3a
gene id: 8078:ap1s3a
uniprot id: A0A147A9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

8078:LOC105929534
gene id: 8078:LOC105929534
uniprot id: A0A3Q2Q5Q3
names: Similarity
messages: Belongs to the OXR1 family.

8078:rgma
gene id: 8078:rgma
uniprot id: A0A146SLP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

8078:bcl2l1
gene id: 8078:bcl2l1
uniprot id: A0A3Q2QPL9
names: Similarity
messages: Belongs to the Bcl-2 family.

8078:evla
gene id: 8078:evla
uniprot id: A0A3Q2P3H4
uniprot id: A0A3Q2P4C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: lamellipodium
messages: stress fiber

8078:map3k21
gene id: 8078:map3k21
uniprot id: A0A3Q2QYY2
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

8078:LOC105916074
gene id: 8078:LOC105916074
uniprot id: A0A146NVL9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:ndufs6
gene id: 8078:ndufs6
uniprot id: A0A146W7Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

8078:LOC105925913
gene id: 8078:LOC105925913
uniprot id: A0A146X760
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

8078:psmd9
gene id: 8078:psmd9
uniprot id: A0A3Q2Q765
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

8078:ifrd1
gene id: 8078:ifrd1
uniprot id: A0A3Q2SMZ3
names: Similarity
messages: Belongs to the IFRD family.

8078:si:dkey-1h24.2
gene id: 8078:si:dkey-1h24.2
uniprot id: A0A147AYS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:kdsr
gene id: 8078:kdsr
uniprot id: A0A3Q2PPP7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:fam53b
gene id: 8078:fam53b
uniprot id: A0A146X4S5
names: Similarity
messages: Belongs to the FAM53 family.

8078:tnfsf13b
gene id: 8078:tnfsf13b
uniprot id: A0A3Q2PQ13
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8078:ndufs8b
gene id: 8078:ndufs8b
uniprot id: A0A146W1N3
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

8078:akt3a
gene id: 8078:akt3a
uniprot id: A0A3Q2PW73
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

8078:mpeg1.1
gene id: 8078:mpeg1.1
uniprot id: A0A3Q2PGI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

8078:hs2st1a
gene id: 8078:hs2st1a
uniprot id: A0A147ADV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

8078:LOC105926380
gene id: 8078:LOC105926380
uniprot id: A0A3Q2PRE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

8078:paqr7b
gene id: 8078:paqr7b
uniprot id: A0A3Q2PT37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8078:map1lc3b
gene id: 8078:map1lc3b
uniprot id: A0A3Q2SUH9
names: Similarity
messages: Belongs to the ATG8 family.

8078:smc6
gene id: 8078:smc6
uniprot id: A0A3Q2NT46
names: Subcellular Location Annotation
messages: Chromosome

8078:dvl1a
gene id: 8078:dvl1a
uniprot id: A0A3Q2TRA3
names: Similarity
messages: Belongs to the DSH family.

8078:drd4-rs
gene id: 8078:drd4-rs
uniprot id: A0A146ZRB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:agpat5
gene id: 8078:agpat5
uniprot id: A0A147B172
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8078:LOC105930601
gene id: 8078:LOC105930601
uniprot id: A0A3Q2P1C0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C14A family.
messages: Cytoplasm
messages: Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (Caspase-6 subunit p18) and a 11 kDa (Caspase-6 subunit p11) subunit.
messages: Nucleus

8078:LOC105928534
gene id: 8078:LOC105928534
uniprot id: A0A3Q2PV68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8078:spata18
gene id: 8078:spata18
uniprot id: A0A146SM04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIEAP family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

8078:LOC105923613
gene id: 8078:LOC105923613
uniprot id: A0A3Q2PLQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

8078:atp23
gene id: 8078:atp23
uniprot id: A0A147A4M9
names: Similarity
messages: Belongs to the peptidase M76 family.

8078:noc2l
gene id: 8078:noc2l
uniprot id: A0A3Q2QB11
names: Similarity
messages: Belongs to the NOC2 family.

8078:hoxb3a
gene id: 8078:hoxb3a
uniprot id: A0A147AQI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8078:reep3b
gene id: 8078:reep3b
uniprot id: A0A146ZT39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

8078:LOC105931567
gene id: 8078:LOC105931567
uniprot id: A0A3Q2UEC0
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: C1 is a calcium-dependent trimolecular complex of C1q, C1r and C1s in the molar ration of 1:2:2. C1r is a dimer of identical chains, each of which is activated by cleavage into two chains, A and B, connected by disulfide bonds.
messages: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8078:si:dkey-79d12.5
gene id: 8078:si:dkey-79d12.5
uniprot id: A0A3Q2P9T5
names: Similarity
messages: Belongs to the BTG family.

8078:slc30a7
gene id: 8078:slc30a7
uniprot id: A0A3Q2Q712
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Homooligomer.
messages: Membrane
messages: trans-Golgi network membrane

8078:susd1
gene id: 8078:susd1
uniprot id: A0A3Q2U3U9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:vdac1
gene id: 8078:vdac1
uniprot id: A0A3Q2UMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

8078:LOC105915883
gene id: 8078:LOC105915883
uniprot id: A0A3Q2PLM7
names: Similarity
messages: Belongs to the dapper family.

8078:cmpk
gene id: 8078:cmpk
uniprot id: A0A3Q2PPF2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

8078:cpsf6
gene id: 8078:cpsf6
uniprot id: A0A146ZB73
uniprot id: A0A3Q2QXU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Cytoplasm
messages: Nucleus speckle
messages: nucleoplasm

8078:mrpl3
gene id: 8078:mrpl3
uniprot id: A0A3Q2NME4
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

8078:gnb2
gene id: 8078:gnb2
uniprot id: A0A146MZG3
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8078:hpxa
gene id: 8078:hpxa
uniprot id: A0A147A2T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemopexin family.
messages: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
messages: Secreted

8078:ssbp1
gene id: 8078:ssbp1
uniprot id: A0A146NN19
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

8078:nrp1a
gene id: 8078:nrp1a
uniprot id: A0A3Q2QWY8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105917435
gene id: 8078:LOC105917435
uniprot id: A0A3Q2PSM4
names: Similarity
messages: Belongs to the intermediate filament family.

8078:ip6k2b
gene id: 8078:ip6k2b
uniprot id: A0A146P6R5
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8078:exoc3l2a
gene id: 8078:exoc3l2a
uniprot id: A0A3Q2NX82
names: Similarity
messages: Belongs to the SEC6 family.

8078:ap3s2
gene id: 8078:ap3s2
uniprot id: A0A3Q2PBH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

8078:si:ch211-233h19.2
gene id: 8078:si:ch211-233h19.2
uniprot id: A0A146ZIT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

8078:brpf1
gene id: 8078:brpf1
uniprot id: A0A3Q2NNR8
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105915758
gene id: 8078:LOC105915758
uniprot id: A0A3Q2UG58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

8078:LOC105927912
gene id: 8078:LOC105927912
uniprot id: A0A146Z4N4
names: Subcellular Location Annotation
messages: Membrane

8078:prop1
gene id: 8078:prop1
uniprot id: A0A3Q2QZR6
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105915412
gene id: 8078:LOC105915412
uniprot id: A0A3Q2P9N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8078:taf6l
gene id: 8078:taf6l
uniprot id: A0A3Q2R485
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

8078:naxe
gene id: 8078:naxe
uniprot id: A0A3Q2PP90
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Secreted

8078:LOC105935972
gene id: 8078:LOC105935972
uniprot id: A0A146PBJ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:LOC105933186
gene id: 8078:LOC105933186
uniprot id: A0A3Q2UKQ0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8078:asrgl1
gene id: 8078:asrgl1
uniprot id: A0A3Q2PTB5
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8078:LOC105934656
gene id: 8078:LOC105934656
uniprot id: A0A3Q2PQL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105930022
gene id: 8078:LOC105930022
uniprot id: A0A3Q2PJF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:enkur
gene id: 8078:enkur
uniprot id: A0A3Q2Q7Y8
names: Subcellular Location Annotation
messages: cilium axoneme

8078:gipc3
gene id: 8078:gipc3
uniprot id: A0A3Q2QW84
names: Similarity
messages: Belongs to the GIPC family.

8078:hbp1
gene id: 8078:hbp1
uniprot id: A0A3Q2U7B9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

8078:LOC105937203
gene id: 8078:LOC105937203
uniprot id: A0A3Q2P0W0
names: Similarity
messages: Belongs to the SMEK family.

8078:LOC105931589
gene id: 8078:LOC105931589
uniprot id: A0A3Q2PFS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

8078:cpsf4
gene id: 8078:cpsf4
uniprot id: A0A3Q2QK36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

8078:LOC105934303
gene id: 8078:LOC105934303
uniprot id: A0A146ZVX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8078:dhrs7
gene id: 8078:dhrs7
uniprot id: A0A3Q2QG58
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:LOC105916436
gene id: 8078:LOC105916436
uniprot id: A0A146YMZ5
names: Subcellular Location Annotation
messages: Membrane

8078:acad11
gene id: 8078:acad11
uniprot id: A0A3Q2QU29
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8078:si:ch211-244c8.4
gene id: 8078:si:ch211-244c8.4
uniprot id: A0A3Q2UI98
names: Similarity
messages: Belongs to the Amer family.

8078:ampd3b
gene id: 8078:ampd3b
uniprot id: A0A3Q2R1D2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

8078:mdh1ab
gene id: 8078:mdh1ab
uniprot id: A0A3Q2T603
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

8078:lin7a
gene id: 8078:lin7a
uniprot id: A0A3Q2R0Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

8078:trim32
gene id: 8078:trim32
uniprot id: A0A3Q2QAG7
names: Similarity
messages: Belongs to the TRIM/RBCC family.

8078:rb1
gene id: 8078:rb1
uniprot id: Q5J3Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

8078:zgc:172121
gene id: 8078:zgc:172121
uniprot id: A0A147ACG9
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

8078:zgc:101100
gene id: 8078:zgc:101100
uniprot id: A0A3Q2R1D3
names: Subcellular Location Annotation
messages: Nucleus

8078:cln5
gene id: 8078:cln5
uniprot id: A0A3Q2PDE4
names: Similarity
messages: Belongs to the CLN5 family.

8078:aldh5a1
gene id: 8078:aldh5a1
uniprot id: A0A146P5F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
messages: Homotetramer.
messages: Mitochondrion

8078:sfrp2l
gene id: 8078:sfrp2l
uniprot id: A0A147AH70
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:yars1
gene id: 8078:yars1
uniprot id: A0A3Q2UQA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus

8078:dgkaa
gene id: 8078:dgkaa
uniprot id: A0A3Q2QDR3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8078:LOC105919870
gene id: 8078:LOC105919870
uniprot id: A0A146PEA8
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

8078:mfsd8l1
gene id: 8078:mfsd8l1
uniprot id: A0A3Q2PT00
names: Subcellular Location Annotation
messages: Membrane

8078:antxr2a
gene id: 8078:antxr2a
uniprot id: A0A147A729
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

8078:fam83d
gene id: 8078:fam83d
uniprot id: A0A3Q2Q630
names: Similarity
messages: Belongs to the FAM83 family.

8078:nrm
gene id: 8078:nrm
uniprot id: A0A3Q2P8L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Membrane
messages: Nucleus inner membrane

8078:rpa1
gene id: 8078:rpa1
uniprot id: A0A3Q2U0G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

8078:gadd45gb.1
gene id: 8078:gadd45gb.1
uniprot id: A0A3Q2PLQ2
names: Similarity
messages: Belongs to the GADD45 family.

8078:foxj1a
gene id: 8078:foxj1a
uniprot id: A0A3Q2Q1V7
names: Subcellular Location Annotation
messages: Nucleus

8078:polr2f
gene id: 8078:polr2f
uniprot id: A0A146ZNR2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: Nucleus

8078:LOC105939654
gene id: 8078:LOC105939654
uniprot id: A0A3Q2P1A6
names: Subcellular Location Annotation
messages: extracellular space

8078:LOC105917979
gene id: 8078:LOC105917979
uniprot id: A0A3Q2UPM2
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

8078:eif2s2
gene id: 8078:eif2s2
uniprot id: A0A146ZR01
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

8078:LOC105918293
gene id: 8078:LOC105918293
uniprot id: A0A3Q2QNA4
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

8078:slitrk4
gene id: 8078:slitrk4
uniprot id: A0A146YBL5
names: Similarity
messages: Belongs to the SLITRK family.

8078:stat5a
gene id: 8078:stat5a
uniprot id: A0A146P8C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8078:LOC105933206
gene id: 8078:LOC105933206
uniprot id: A0A146VZZ2
uniprot id: A0A146ZYD1
uniprot id: A0A3Q2UJI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

8078:noc4l
gene id: 8078:noc4l
uniprot id: A0A3Q2QII2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Nucleus membrane

8078:aldocb
gene id: 8078:aldocb
uniprot id: A0A147AR05
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

8078:ppa1a
gene id: 8078:ppa1a
uniprot id: A0A3Q2QNI9
names: Similarity
messages: Belongs to the PPase family.

8078:meis3
gene id: 8078:meis3
uniprot id: A0A147APM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8078:LOC105932586
gene id: 8078:LOC105932586
uniprot id: A0A3Q2QSC7
names: Similarity
messages: Belongs to the peptidase C14A family.

8078:eif4e2
gene id: 8078:eif4e2
uniprot id: A0A3Q2TZQ4
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

8078:hoxa13b
gene id: 8078:hoxa13b
uniprot id: A0A3Q2PKG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8078:cenpl
gene id: 8078:cenpl
uniprot id: A0A147AM15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

8078:LOC105939868
gene id: 8078:LOC105939868
uniprot id: A0A146UXT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

8078:lsm14b
gene id: 8078:lsm14b
uniprot id: A0A3Q2U4A3
names: Similarity
messages: Belongs to the LSM14 family.

8078:dpysl2b
gene id: 8078:dpysl2b
uniprot id: A0A147A8U7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

8078:usp1
gene id: 8078:usp1
uniprot id: A0A3Q2NP83
names: Similarity
messages: Belongs to the peptidase C19 family.

8078:hmgb1b
gene id: 8078:hmgb1b
uniprot id: A0A3Q2PCW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

8078:si:ch211-121a2.4
gene id: 8078:si:ch211-121a2.4
uniprot id: A0A3Q2NN47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

8078:hyal3
gene id: 8078:hyal3
uniprot id: A0A3Q2QVX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Early endosome
messages: Endoplasmic reticulum
messages: Endosome
messages: Membrane
messages: acrosome

8078:slc37a3
gene id: 8078:slc37a3
uniprot id: A0A3Q2P5X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8078:metap2a
gene id: 8078:metap2a
uniprot id: A0A3Q2Q760
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

8078:kansl2
gene id: 8078:kansl2
uniprot id: A0A3Q2QKR6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

8078:LOC105931220
gene id: 8078:LOC105931220
uniprot id: A0A3Q2NQZ2
uniprot id: A0A3Q2Q7S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

8078:sncb
gene id: 8078:sncb
uniprot id: A0A3Q2U6H0
names: Similarity
messages: Belongs to the synuclein family.

8078:tprg1
gene id: 8078:tprg1
uniprot id: A0A3Q2P7Y6
names: Similarity
messages: Belongs to the TPRG1 family.

8078:LOC105927638
gene id: 8078:LOC105927638
uniprot id: A0A3Q2Q2B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:tafa5l
gene id: 8078:tafa5l
uniprot id: A0A147ABK4
names: Similarity
messages: Belongs to the TAFA family.

8078:agxt2
gene id: 8078:agxt2
uniprot id: A0A3Q2SU96
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

8078:pgap6
gene id: 8078:pgap6
uniprot id: A0A3Q2PI85
uniprot id: A0A3Q2QRS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

8078:dennd11
gene id: 8078:dennd11
uniprot id: A0A3Q2P0S1
names: Similarity
messages: Belongs to the DENND11 family.

8078:LOC105919235
gene id: 8078:LOC105919235
uniprot id: A0A3Q2TJH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

8078:slc16a7
gene id: 8078:slc16a7
uniprot id: A0A146WRZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8078:LOC105926012
gene id: 8078:LOC105926012
uniprot id: A0A3Q2P0G6
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8078:tspan36
gene id: 8078:tspan36
uniprot id: A0A3Q2PPZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:gadd45aa
gene id: 8078:gadd45aa
uniprot id: A0A3Q2UL35
names: Similarity
messages: Belongs to the GADD45 family.

8078:LOC105937254
gene id: 8078:LOC105937254
uniprot id: A0A3Q2Q7W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

8078:LOC105928565
gene id: 8078:LOC105928565
uniprot id: A0A3Q2QQH1
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

8078:ift20
gene id: 8078:ift20
uniprot id: A0A3Q2Q5K6
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

8078:anxa13
gene id: 8078:anxa13
uniprot id: A0A146P462
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8078:pdhx
gene id: 8078:pdhx
uniprot id: A0A3Q2QHQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

8078:LOC105936828
gene id: 8078:LOC105936828
uniprot id: A0A146ZQ03
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8078:ada
gene id: 8078:ada
uniprot id: A0A147AT74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

8078:LOC105940135
gene id: 8078:LOC105940135
uniprot id: A0A3Q2NVF2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8078:ube2b
gene id: 8078:ube2b
uniprot id: A0A3Q2PXH3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:LOC105937874
gene id: 8078:LOC105937874
uniprot id: A0A3Q2NXP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

8078:dtd1
gene id: 8078:dtd1
uniprot id: A0A3Q2NZW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

8078:l3mbtl2
gene id: 8078:l3mbtl2
uniprot id: A0A3Q2PNW4
uniprot id: A0A3Q2PPY5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, BAT8 and YAF2.
messages: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.

8078:LOC105927892
gene id: 8078:LOC105927892
uniprot id: A0A3Q2Q5C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

8078:dnase1
gene id: 8078:dnase1
uniprot id: A0A3Q2QZQ1
names: Similarity
messages: Belongs to the DNase I family.

8078:gbp
gene id: 8078:gbp
uniprot id: A0A3Q2PF41
names: Similarity
messages: Belongs to the GSK-3-binding protein family.

8078:gtf2f1
gene id: 8078:gtf2f1
uniprot id: A0A3Q2UHE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

8078:egr1
gene id: 8078:egr1
uniprot id: A0A3Q2QMG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

8078:LOC105938951
gene id: 8078:LOC105938951
uniprot id: A0A3Q2PFE4
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

8078:zdhhc2
gene id: 8078:zdhhc2
uniprot id: A0A146WL20
uniprot id: A0A146WNA9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8078:slc48a1a
gene id: 8078:slc48a1a
uniprot id: A0A146ZSZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.
messages: Lysosome membrane
messages: Membrane

8078:LOC105925299
gene id: 8078:LOC105925299
uniprot id: A0A146Z4Z3
names: Subcellular Location Annotation
messages: Membrane
messages: chromaffin granule membrane

8078:atp10a
gene id: 8078:atp10a
uniprot id: A0A147ACK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8078:nr1d2a
gene id: 8078:nr1d2a
uniprot id: A0A3Q2P5S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8078:LOC105917156
gene id: 8078:LOC105917156
uniprot id: A0A3Q2QFK2
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

8078:LOC105919210
gene id: 8078:LOC105919210
uniprot id: A0A3Q2QLM6
names: Subunit
messages: Monomer.

8078:supt4h1
gene id: 8078:supt4h1
uniprot id: A0A146P4Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

8078:LOC105934707
gene id: 8078:LOC105934707
uniprot id: A0A3Q2NP50
names: Similarity
messages: Belongs to the ARTD/PARP family.

8078:rom1a
gene id: 8078:rom1a
uniprot id: A0A147A003
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

8078:zgc:92313
gene id: 8078:zgc:92313
uniprot id: A0A3Q2Q6S9
names: Subcellular Location Annotation
messages: extracellular space

8078:cript
gene id: 8078:cript
uniprot id: A0A146Y7H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

8078:nr4a3
gene id: 8078:nr4a3
uniprot id: A0A147B071
uniprot id: A0A3Q2QPZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:LOC105920348
gene id: 8078:LOC105920348
uniprot id: A0A3Q2PQY1
names: Similarity
messages: Belongs to the WAPL family.

8078:sec31a
gene id: 8078:sec31a
uniprot id: A0A3Q2U4S2
uniprot id: A0A3Q2U4V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

8078:LOC105929808
gene id: 8078:LOC105929808
uniprot id: A0A3Q2TFS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:LOC105932300
gene id: 8078:LOC105932300
uniprot id: A0A3Q2NSP5
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:fgf1a
gene id: 8078:fgf1a
uniprot id: A0A3Q2T6H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

8078:eri1
gene id: 8078:eri1
uniprot id: A0A3Q2NSY6
names: Subcellular Location Annotation
messages: Cytoplasm

8078:LOC105930425
gene id: 8078:LOC105930425
uniprot id: A0A3Q2PGY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:tmem186
gene id: 8078:tmem186
uniprot id: A0A3Q2QM72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM186 family.
messages: Membrane

8078:npm3
gene id: 8078:npm3
uniprot id: A0A3Q2Q8F0
names: Similarity
messages: Belongs to the nucleoplasmin family.

8078:mybpha
gene id: 8078:mybpha
uniprot id: A0A3Q2QAQ1
names: Subcellular Location Annotation
messages: Membrane

8078:pank4
gene id: 8078:pank4
uniprot id: A0A146V1L8
names: Similarity
names: Subunit
messages: Belongs to the type II pantothenate kinase family.
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.

8078:magoh
gene id: 8078:magoh
uniprot id: A0A146NEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

8078:tmod2
gene id: 8078:tmod2
uniprot id: A0A3Q2U6Z6
names: Subcellular Location Annotation
messages: cytoskeleton

8078:ints12
gene id: 8078:ints12
uniprot id: A0A3Q2R1C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 12 family.
messages: Nucleus

8078:crema
gene id: 8078:crema
uniprot id: A0A3Q2QNH7
names: Subcellular Location Annotation
messages: Nucleus

8078:tspan18b
gene id: 8078:tspan18b
uniprot id: A0A3Q2T262
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:eif4enif1
gene id: 8078:eif4enif1
uniprot id: A0A3Q2PKH9
names: Subcellular Location Annotation
messages: Cytoplasm

8078:lhfpl6
gene id: 8078:lhfpl6
uniprot id: A0A3Q2PGJ5
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105928256
gene id: 8078:LOC105928256
uniprot id: A0A3Q2QKJ5
names: Similarity
messages: Belongs to the CDR2 family.

8078:uck1
gene id: 8078:uck1
uniprot id: A0A3Q2QGJ5
names: Similarity
messages: Belongs to the uridine kinase family.

8078:LOC105928229
gene id: 8078:LOC105928229
uniprot id: A0A146XCW3
names: Similarity
messages: Belongs to the fatty acid desaturase type 1 family.

8078:laptm4a
gene id: 8078:laptm4a
uniprot id: A0A3Q2TS70
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

8078:ugt2b3
gene id: 8078:ugt2b3
uniprot id: A0A3Q2NU28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8078:LOC105918354
gene id: 8078:LOC105918354
uniprot id: A0A146P9L1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8078:mrps18c
gene id: 8078:mrps18c
uniprot id: A0A3Q2PV11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Mitochondrion

8078:c12h2orf68
gene id: 8078:c12h2orf68
uniprot id: A0A147A9J2
names: Similarity
messages: Belongs to the UPF0561 family.

8078:arf1
gene id: 8078:arf1
uniprot id: A0A3Q2QK20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8078:slc16a4
gene id: 8078:slc16a4
uniprot id: A0A3Q2NXG1
names: Subcellular Location Annotation
messages: Membrane

8078:kcnk1b
gene id: 8078:kcnk1b
uniprot id: A0A147AHC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

8078:slc8b1
gene id: 8078:slc8b1
uniprot id: A0A147A9C9
names: Subcellular Location Annotation
messages: Membrane

8078:mfn2
gene id: 8078:mfn2
uniprot id: A0A3Q2T690
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8078:mmp19
gene id: 8078:mmp19
uniprot id: A0A146V2C6
names: Similarity
messages: Belongs to the peptidase M10A family.

8078:rgs9bp
gene id: 8078:rgs9bp
uniprot id: A0A3Q2QX57
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

8078:derl3
gene id: 8078:derl3
uniprot id: A0A3Q2Q152
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

8078:LOC105934955
gene id: 8078:LOC105934955
uniprot id: A0A3Q2QTQ3
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

8078:LOC105921474
gene id: 8078:LOC105921474
uniprot id: A0A3Q2Q428
names: Similarity
messages: Belongs to the IUNH family.

8078:LOC105933356
gene id: 8078:LOC105933356
uniprot id: A0A3Q2QP82
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

8078:p2rx5
gene id: 8078:p2rx5
uniprot id: A0A3Q2QLN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8078:txlna
gene id: 8078:txlna
uniprot id: A0A3Q2THC8
names: Similarity
messages: Belongs to the taxilin family.

8078:si:ch211-39i2.2
gene id: 8078:si:ch211-39i2.2
uniprot id: A0A3Q2PP74
names: Similarity
messages: Belongs to the DDIT4 family.

8078:sdc4
gene id: 8078:sdc4
uniprot id: A0A3Q2T8E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

8078:nptnb
gene id: 8078:nptnb
uniprot id: A0A146WF42
names: Subcellular Location Annotation
messages: Membrane

8078:ywhae1
gene id: 8078:ywhae1
uniprot id: A0A146N3A6
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8078:pdgfd
gene id: 8078:pdgfd
uniprot id: A0A3Q2NTU4
names: Caution
names: Subunit
messages: Homodimer; disulfide-linked. Interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:pigx
gene id: 8078:pigx
uniprot id: A0A146WQ68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.

8078:tmprss2
gene id: 8078:tmprss2
uniprot id: A0A3Q2PH13
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8078:egr3
gene id: 8078:egr3
uniprot id: A0A3Q2TLT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

8078:LOC105934166
gene id: 8078:LOC105934166
uniprot id: A0A3Q2Q1X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8078:bmp15
gene id: 8078:bmp15
uniprot id: A0A146ZTS6
names: Similarity
messages: Belongs to the TGF-beta family.

8078:LOC105925770
gene id: 8078:LOC105925770
uniprot id: A0A3Q2QRU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

8078:prox1a
gene id: 8078:prox1a
uniprot id: A0A3Q2NNC1
names: Subcellular Location Annotation
messages: Nucleus

8078:uhrf1
gene id: 8078:uhrf1
uniprot id: A0A146UWL1
names: Subcellular Location Annotation
messages: Nucleus

8078:serbp1a
gene id: 8078:serbp1a
uniprot id: A0A146W2M4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8078:shroom1
gene id: 8078:shroom1
uniprot id: A0A3Q2NVZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

8078:LOC105918367
gene id: 8078:LOC105918367
uniprot id: A0A146NTR7
names: Similarity
messages: Belongs to the peptidase C14A family.

8078:zmp:0000000521
gene id: 8078:zmp:0000000521
uniprot id: A0A146MK78
names: Similarity
messages: Belongs to the SPIN/STSY family.

8078:tnfrsf1b
gene id: 8078:tnfrsf1b
uniprot id: A0A3Q2Q1Z5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:meis1b
gene id: 8078:meis1b
uniprot id: A0A146W2K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8078:arrdc3a
gene id: 8078:arrdc3a
uniprot id: A0A146P4E6
names: Similarity
messages: Belongs to the arrestin family.

8078:fmnl1a
gene id: 8078:fmnl1a
uniprot id: A0A146NZ57
names: Similarity
messages: Belongs to the formin homology family.

8078:atp5if1
gene id: 8078:atp5if1
uniprot id: A0A146VP86
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

8078:tmem38b
gene id: 8078:tmem38b
uniprot id: A0A3Q2Q8G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

8078:fam199x
gene id: 8078:fam199x
uniprot id: A0A146NVV2
names: Similarity
messages: Belongs to the FAM199 family.

8078:nr2f5
gene id: 8078:nr2f5
uniprot id: A0A146MR75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:dipk2ab
gene id: 8078:dipk2ab
uniprot id: A0A3Q2THD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

8078:pcolceb
gene id: 8078:pcolceb
uniprot id: A0A3Q2NXA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105918461
gene id: 8078:LOC105918461
uniprot id: A0A3Q2STQ4
names: Similarity
messages: Belongs to the FAM102 family.

8078:LOC105935076
gene id: 8078:LOC105935076
uniprot id: Q6RIA8
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:LOC105919263
gene id: 8078:LOC105919263
uniprot id: A0A3Q2UKN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8078:eps8l3b
gene id: 8078:eps8l3b
uniprot id: A0A3Q2NYY9
names: Similarity
messages: Belongs to the EPS8 family.

8078:arpc4
gene id: 8078:arpc4
uniprot id: A0A146P736
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

8078:homer1b
gene id: 8078:homer1b
uniprot id: A0A147ACR7
uniprot id: A0A3Q2NZU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

8078:actr8
gene id: 8078:actr8
uniprot id: A0A3Q2UQH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

8078:LOC105916446
gene id: 8078:LOC105916446
uniprot id: A0A3Q2QNI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

8078:LOC105931042
gene id: 8078:LOC105931042
uniprot id: A0A146P5R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

8078:hsd17b10
gene id: 8078:hsd17b10
uniprot id: A0A3Q2PC82
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:rpl18a
gene id: 8078:rpl18a
uniprot id: A0A3Q2QIF2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

8078:LOC105931784
gene id: 8078:LOC105931784
uniprot id: A0A3Q2NY71
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

8078:zdhhc9
gene id: 8078:zdhhc9
uniprot id: A0A146P4F1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8078:ubiad1
gene id: 8078:ubiad1
uniprot id: A0A146P3U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

8078:pld1b
gene id: 8078:pld1b
uniprot id: A0A147AXC1
names: Similarity
messages: Belongs to the phospholipase D family.

8078:dapk3
gene id: 8078:dapk3
uniprot id: A0A146QQI8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:LOC105938470
gene id: 8078:LOC105938470
uniprot id: A0A3Q2NS56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8078:LOC105939023
gene id: 8078:LOC105939023
uniprot id: A0A146V2Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:LOC105916168
gene id: 8078:LOC105916168
uniprot id: A0A3Q2SZ82
names: Similarity
messages: Belongs to the peptidase M14 family.

8078:LOC105937825
gene id: 8078:LOC105937825
uniprot id: A0A3Q2PMG8
names: Function
names: Similarity
messages: Belongs to the intermediate filament family.
messages: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.

8078:slc44a5b
gene id: 8078:slc44a5b
uniprot id: A0A3Q2Q590
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8078:pou4f2
gene id: 8078:pou4f2
uniprot id: A0A3Q2QEZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8078:intu
gene id: 8078:intu
uniprot id: A0A3Q2Q1N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inturned family.
messages: Cell surface
messages: cilium basal body

8078:nek8
gene id: 8078:nek8
uniprot id: A0A147AWS2
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

8078:dhrs1
gene id: 8078:dhrs1
uniprot id: A0A3Q2PS77
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:lsm7
gene id: 8078:lsm7
uniprot id: A0A3Q2QDD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

8078:LOC105934257
gene id: 8078:LOC105934257
uniprot id: A0A146ZUZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

8078:foxe1
gene id: 8078:foxe1
uniprot id: A0A146QN90
names: Subcellular Location Annotation
messages: Nucleus

8078:cdh11
gene id: 8078:cdh11
uniprot id: A0A146Q7N1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8078:LOC105940280
gene id: 8078:LOC105940280
uniprot id: A0A146P5B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

8078:sult1st6
gene id: 8078:sult1st6
uniprot id: A0A146YQB1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8078:LOC105930940
gene id: 8078:LOC105930940
uniprot id: A0A3Q2UFL3
names: Subunit
messages: Monomer and homodimer; homodimerization is induced by binding of the substrate.

8078:cdkn2aip
gene id: 8078:cdkn2aip
uniprot id: A0A3Q2PPS4
names: Similarity
messages: Belongs to the CARF family.

8078:fam83b
gene id: 8078:fam83b
uniprot id: A0A3Q2QFN6
names: Similarity
messages: Belongs to the FAM83 family.

8078:LOC105939041
gene id: 8078:LOC105939041
uniprot id: A0A3Q2U9H6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8078:rpe
gene id: 8078:rpe
uniprot id: A0A3Q2QVU4
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

8078:ppargc1b
gene id: 8078:ppargc1b
uniprot id: A0A3Q2UFX4
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105929953
gene id: 8078:LOC105929953
uniprot id: A0A3Q2P8G0
uniprot id: A0A3Q2QIU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8078:scrn3
gene id: 8078:scrn3
uniprot id: A0A3Q2NY05
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

8078:adssl
gene id: 8078:adssl
uniprot id: A0A3Q2NZE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

8078:LOC105936522
gene id: 8078:LOC105936522
uniprot id: A0A3Q2QTW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

8078:rpl39
gene id: 8078:rpl39
uniprot id: A0A3Q2QX78
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

8078:eif3c
gene id: 8078:eif3c
uniprot id: A0A146YHT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8078:LOC105931420
gene id: 8078:LOC105931420
uniprot id: A0A3Q2QXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

8078:LOC105937993
gene id: 8078:LOC105937993
uniprot id: A0A3Q2T006
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:parp16
gene id: 8078:parp16
uniprot id: A0A3Q2QHH5
names: Similarity
messages: Belongs to the ARTD/PARP family.

8078:czib
gene id: 8078:czib
uniprot id: A0A3Q2TDP9
names: Similarity
messages: Belongs to the UPF0587 family.

8078:chaf1b
gene id: 8078:chaf1b
uniprot id: A0A3Q2PRJ3
names: Subcellular Location Annotation
messages: Nucleus

8078:ppm1na
gene id: 8078:ppm1na
uniprot id: A0A3Q2QUZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8078:LOC105919068
gene id: 8078:LOC105919068
uniprot id: A0A3Q2PBN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8078:si:dkey-251i10.1
gene id: 8078:si:dkey-251i10.1
uniprot id: A0A147AR18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

8078:sncgb
gene id: 8078:sncgb
uniprot id: A0A3Q2P9B0
names: Similarity
messages: Belongs to the synuclein family.

8078:svild
gene id: 8078:svild
uniprot id: A0A3Q2PQ28
names: Similarity
messages: Belongs to the villin/gelsolin family.

8078:cep57
gene id: 8078:cep57
uniprot id: A0A3Q2QDH5
names: Similarity
messages: Belongs to the translokin family.

8078:LOC105933849
gene id: 8078:LOC105933849
uniprot id: A0A3Q2T1C7
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8078:taf5l
gene id: 8078:taf5l
uniprot id: A0A3Q2SSM5
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

8078:klhl22
gene id: 8078:klhl22
uniprot id: A0A3Q2QLZ7
names: Subcellular Location Annotation
messages: Lysosome
messages: Nucleus
messages: centrosome
messages: cytosol
messages: spindle

8078:nr2f1a
gene id: 8078:nr2f1a
uniprot id: A0A3Q2P467
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:man1a1
gene id: 8078:man1a1
uniprot id: A0A3Q2P6V5
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8078:agmat
gene id: 8078:agmat
uniprot id: A0A146ZT02
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

8078:LOC105939131
gene id: 8078:LOC105939131
uniprot id: A0A3Q2QBZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8078:trhr2
gene id: 8078:trhr2
uniprot id: A0A3Q2PPP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

8078:fabp3
gene id: 8078:fabp3
uniprot id: Q90W92
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8078:ccnf
gene id: 8078:ccnf
uniprot id: A0A3Q2T6I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: centriole
messages: perinuclear region

8078:runx3
gene id: 8078:runx3
uniprot id: A0A147ABD8
uniprot id: A0A3Q2P2K1
names: Subcellular Location Annotation
messages: Nucleus

8078:cd44b
gene id: 8078:cd44b
uniprot id: A0A3Q2P830
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

8078:LOC105921058
gene id: 8078:LOC105921058
uniprot id: A0A3Q2QAS7
uniprot id: A0A3Q2SVL2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:aldh8a1
gene id: 8078:aldh8a1
uniprot id: A0A3Q2U5A1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8078:gpr37a
gene id: 8078:gpr37a
uniprot id: A0A3Q2R0C7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:cuedc2
gene id: 8078:cuedc2
uniprot id: A0A3Q2Q107
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

8078:rbck1
gene id: 8078:rbck1
uniprot id: A0A146VJ08
names: Similarity
messages: Belongs to the RBR family.

8078:mrps30
gene id: 8078:mrps30
uniprot id: A0A3Q2NVS3
names: Subcellular Location Annotation
messages: Mitochondrion

8078:rxraa
gene id: 8078:rxraa
uniprot id: A0A3Q2QQ23
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

8078:scara5
gene id: 8078:scara5
uniprot id: A0A3Q2UFW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCARA5 family.
messages: Cell membrane
messages: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways.
messages: Homotrimer.
messages: Membrane

8078:ppp1r10
gene id: 8078:ppp1r10
uniprot id: A0A3Q2PR99
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers.

8078:LOC105933673
gene id: 8078:LOC105933673
uniprot id: A0A146ZWD8
names: Subcellular Location Annotation
messages: cytoskeleton

8078:fam193b
gene id: 8078:fam193b
uniprot id: A0A3Q2QGD2
names: Similarity
messages: Belongs to the FAM193 family.

8078:LOC105926326
gene id: 8078:LOC105926326
uniprot id: A0A3Q2PID8
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

8078:LOC105927741
gene id: 8078:LOC105927741
uniprot id: A0A3Q2NVI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8078:kiz
gene id: 8078:kiz
uniprot id: A0A147ACH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kizuna family.
messages: Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
messages: centrosome
messages: cilium basal body

8078:maea
gene id: 8078:maea
uniprot id: A0A146NUX1
names: Subcellular Location Annotation
messages: Nucleus matrix

8078:LOC105923427
gene id: 8078:LOC105923427
uniprot id: A0A3Q2PNT3
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:hsp90aa1.2
gene id: 8078:hsp90aa1.2
uniprot id: A0A3Q2PUA0
names: Similarity
messages: Belongs to the heat shock protein 90 family.

8078:ctps1a
gene id: 8078:ctps1a
uniprot id: A0A146NWA6
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

8078:pnp6
gene id: 8078:pnp6
uniprot id: A0A3Q2QLS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

8078:LOC105916095
gene id: 8078:LOC105916095
uniprot id: A0A3Q2QIT5
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

8078:smo
gene id: 8078:smo
uniprot id: A0A3Q2PWF8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:anapc1
gene id: 8078:anapc1
uniprot id: A0A3Q2P293
names: Similarity
messages: Belongs to the APC1 family.

8078:si:dkey-91i10.3
gene id: 8078:si:dkey-91i10.3
uniprot id: A0A3Q2PN25
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:fam221a
gene id: 8078:fam221a
uniprot id: A0A3Q2PNF4
names: Similarity
messages: Belongs to the FAM221 family.

8078:tmem245
gene id: 8078:tmem245
uniprot id: A0A146PSG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

8078:dcp1a
gene id: 8078:dcp1a
uniprot id: A0A3Q2R2N3
names: Similarity
messages: Belongs to the DCP1 family.

8078:LOC105933124
gene id: 8078:LOC105933124
uniprot id: A0A3Q2PVL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

8078:camk2g2
gene id: 8078:camk2g2
uniprot id: A0A3Q2P2B8
uniprot id: A0A3Q2SYD2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8078:nrn1lb
gene id: 8078:nrn1lb
uniprot id: A0A3Q2PEA2
names: Similarity
messages: Belongs to the neuritin family.

8078:LOC105927195
gene id: 8078:LOC105927195
uniprot id: A0A3Q2P2T4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:LOC105931389
gene id: 8078:LOC105931389
uniprot id: A0A146W8E2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

8078:LOC105931403
gene id: 8078:LOC105931403
uniprot id: A0A147A1X8
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

8078:wdr12
gene id: 8078:wdr12
uniprot id: A0A3Q2QFS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

8078:tbpl1
gene id: 8078:tbpl1
uniprot id: A0A146WCR6
names: Similarity
messages: Belongs to the TBP family.

8078:opa3
gene id: 8078:opa3
uniprot id: A0A3Q2Q0L8
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

8078:ctbs
gene id: 8078:ctbs
uniprot id: A0A3Q2STU4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

8078:pdia6
gene id: 8078:pdia6
uniprot id: A0A146WBP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

8078:tgfbr2b
gene id: 8078:tgfbr2b
uniprot id: A0A3Q2P867
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Membrane raft

8078:cldn5b
gene id: 8078:cldn5b
uniprot id: A0A3Q2ST31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8078:xkr6b
gene id: 8078:xkr6b
uniprot id: A0A3Q2ULX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8078:sh3bgrl
gene id: 8078:sh3bgrl
uniprot id: A0A146P5Q2
names: Similarity
messages: Belongs to the SH3BGR family.

8078:fzd5
gene id: 8078:fzd5
uniprot id: A0A146P5Q0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:dlb
gene id: 8078:dlb
uniprot id: A0A3Q2NWL4
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8078:jam2b
gene id: 8078:jam2b
uniprot id: A0A3Q2PGK5
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105915960
gene id: 8078:LOC105915960
uniprot id: A0A3Q2PGK7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8078:acvrl1
gene id: 8078:acvrl1
uniprot id: A0A3Q2Q3Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8078:fam83hb
gene id: 8078:fam83hb
uniprot id: A0A3Q2TAF8
names: Similarity
messages: Belongs to the FAM83 family.

8078:LOC105917680
gene id: 8078:LOC105917680
uniprot id: A0A146YF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8078:cacfd1
gene id: 8078:cacfd1
uniprot id: A0A147A5Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

8078:etv1
gene id: 8078:etv1
uniprot id: A0A146ZSN3
uniprot id: A0A3Q2P7Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:camk1db
gene id: 8078:camk1db
uniprot id: A0A3Q2P2J6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:slc25a37
gene id: 8078:slc25a37
uniprot id: A0A3Q2PVC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:cry-dash
gene id: 8078:cry-dash
uniprot id: A0A3Q2UEZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

8078:pdia3
gene id: 8078:pdia3
uniprot id: A0A3Q2QWP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8078:riok3
gene id: 8078:riok3
uniprot id: A0A3Q2UBU2
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

8078:spry1
gene id: 8078:spry1
uniprot id: A0A3Q2QUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: Cytoplasm
messages: Membrane

8078:apom
gene id: 8078:apom
uniprot id: A0A146Y5M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
messages: Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.
messages: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
messages: Secreted

8078:pusl1
gene id: 8078:pusl1
uniprot id: A0A3Q2SXR4
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

8078:pla2g4ab
gene id: 8078:pla2g4ab
uniprot id: A0A3Q2QPS7
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

8078:insig1
gene id: 8078:insig1
uniprot id: A0A147AUB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

8078:kmt5aa
gene id: 8078:kmt5aa
uniprot id: A0A146P704
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8078:LOC105937252
gene id: 8078:LOC105937252
uniprot id: A0A3Q2U0H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8078:ercc1
gene id: 8078:ercc1
uniprot id: A0A3Q2P558
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

8078:got1
gene id: 8078:got1
uniprot id: A0A3Q2NRB0
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

8078:ism2b
gene id: 8078:ism2b
uniprot id: A0A3Q2NY87
names: Similarity
messages: Belongs to the isthmin family.

8078:prmt7
gene id: 8078:prmt7
uniprot id: A0A3Q2PYI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

8078:lpar1
gene id: 8078:lpar1
uniprot id: A0A147A4M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

8078:LOC105931257
gene id: 8078:LOC105931257
uniprot id: A0A3Q2NRZ7
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

8078:ocrl
gene id: 8078:ocrl
uniprot id: A0A146X994
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

8078:LOC105917817
gene id: 8078:LOC105917817
uniprot id: A0A3Q2P0G4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:LOC105925237
gene id: 8078:LOC105925237
uniprot id: A0A3Q2THP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

8078:gng13b
gene id: 8078:gng13b
uniprot id: A0A3Q2PYS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8078:igf1
gene id: 8078:igf1
uniprot id: A0A146PAT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8078:hsd17b12b
gene id: 8078:hsd17b12b
uniprot id: A0A3Q2QJQ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:tmem39b
gene id: 8078:tmem39b
uniprot id: A0A3Q2QUV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

8078:LOC105934611
gene id: 8078:LOC105934611
uniprot id: A0A146VR56
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:micos13
gene id: 8078:micos13
uniprot id: A0A3Q2PEY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

8078:emc3
gene id: 8078:emc3
uniprot id: A0A147A9Y7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

8078:LOC105915442
gene id: 8078:LOC105915442
uniprot id: A0A3Q2QG98
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

8078:krt1-c5
gene id: 8078:krt1-c5
uniprot id: A0A146VBL8
names: Similarity
messages: Belongs to the intermediate filament family.

8078:LOC105920784
gene id: 8078:LOC105920784
uniprot id: A0A3Q2P0J8
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8078:LOC105925841
gene id: 8078:LOC105925841
uniprot id: A0A3Q2T9T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:lin28b
gene id: 8078:lin28b
uniprot id: A0A3Q2R209
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

8078:LOC105915798
gene id: 8078:LOC105915798
uniprot id: A0A3Q2PTJ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:naf1
gene id: 8078:naf1
uniprot id: A0A146NUK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

8078:LOC105933444
gene id: 8078:LOC105933444
uniprot id: A0A146ZWQ0
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

8078:LOC105919289
gene id: 8078:LOC105919289
uniprot id: A0A3Q2TDG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

8078:LOC105931846
gene id: 8078:LOC105931846
uniprot id: A0A146W608
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

8078:LOC105929813
gene id: 8078:LOC105929813
uniprot id: A0A3Q2PJW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

8078:tnfaip1
gene id: 8078:tnfaip1
uniprot id: A0A3Q2SNH8
names: Similarity
messages: Belongs to the BACURD family.

8078:parp12a
gene id: 8078:parp12a
uniprot id: A0A3Q2T7C2
names: Similarity
messages: Belongs to the ARTD/PARP family.

8078:acsl1a
gene id: 8078:acsl1a
uniprot id: A0A3Q2Q2G5
uniprot id: A0A3Q2Q2G9
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8078:npvf
gene id: 8078:npvf
uniprot id: A0A3Q2QNR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

8078:ndrg3a
gene id: 8078:ndrg3a
uniprot id: A0A3Q2PV88
names: Similarity
messages: Belongs to the NDRG family.

8078:gpr37b
gene id: 8078:gpr37b
uniprot id: A0A146SHK2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:coq3
gene id: 8078:coq3
uniprot id: A0A3Q2P9H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

8078:LOC105929210
gene id: 8078:LOC105929210
uniprot id: A0A3Q2PKV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

8078:pde4d
gene id: 8078:pde4d
uniprot id: A0A3Q2PR07
uniprot id: A0A3Q2TGT4
uniprot id: A0A3Q2TGV6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8078:notum1a
gene id: 8078:notum1a
uniprot id: A0A3Q2QFA3
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

8078:ccser2a
gene id: 8078:ccser2a
uniprot id: A0A3Q2R4Q6
uniprot id: A0A3Q2UR46
names: Similarity
messages: Belongs to the CCSER family.

8078:mrpl35
gene id: 8078:mrpl35
uniprot id: A0A3Q2U8M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

8078:psmf1
gene id: 8078:psmf1
uniprot id: A0A3Q2TL33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

8078:LOC105927138
gene id: 8078:LOC105927138
uniprot id: A0A3Q2NYW5
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

8078:fam155a
gene id: 8078:fam155a
uniprot id: A0A3Q2P2U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

8078:LOC105920731
gene id: 8078:LOC105920731
uniprot id: A0A3Q2QJI5
names: Subcellular Location Annotation
messages: Membrane

8078:nudcd1
gene id: 8078:nudcd1
uniprot id: A0A3Q2SYZ7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8078:slc1a9
gene id: 8078:slc1a9
uniprot id: A0A3Q2P138
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8078:pde6hb
gene id: 8078:pde6hb
uniprot id: A0A3Q2QDG7
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8078:LOC105915363
gene id: 8078:LOC105915363
uniprot id: A0A3Q2PE41
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8078:ppil1
gene id: 8078:ppil1
uniprot id: A0A3Q2PK95
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8078:nectin3a
gene id: 8078:nectin3a
uniprot id: A0A3Q2P7V3
names: Subcellular Location Annotation
messages: Membrane

8078:ube2ka
gene id: 8078:ube2ka
uniprot id: A0A3Q2Q3W3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:LOC105930312
gene id: 8078:LOC105930312
uniprot id: A0A147A2S0
names: Subcellular Location Annotation
messages: Membrane

8078:rnft2
gene id: 8078:rnft2
uniprot id: A0A3Q2NW05
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105929708
gene id: 8078:LOC105929708
uniprot id: A0A147A428
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

8078:LOC105931967
gene id: 8078:LOC105931967
uniprot id: A0A3Q2PP09
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

8078:synm
gene id: 8078:synm
uniprot id: A0A3Q2SUB9
names: Similarity
messages: Belongs to the intermediate filament family.

8078:irx1a
gene id: 8078:irx1a
uniprot id: A0A3Q2QDX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8078:alg2
gene id: 8078:alg2
uniprot id: A0A3Q2PK09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

8078:tspan12
gene id: 8078:tspan12
uniprot id: A0A146ZSH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:bud31
gene id: 8078:bud31
uniprot id: A0A146NUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

8078:tor4aa
gene id: 8078:tor4aa
uniprot id: A0A147AVV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Membrane

8078:ide
gene id: 8078:ide
uniprot id: A0A3Q2PZG4
uniprot id: A0A3Q2R2U5
names: Similarity
messages: Belongs to the peptidase M16 family.

8078:LOC105934646
gene id: 8078:LOC105934646
uniprot id: A0A3Q2NPX9
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8078:LOC105915823
gene id: 8078:LOC105915823
uniprot id: A0A146P5Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8078:cass4
gene id: 8078:cass4
uniprot id: A0A146ZW30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

8078:phf10
gene id: 8078:phf10
uniprot id: A0A3Q2PBC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

8078:cnn2
gene id: 8078:cnn2
uniprot id: A0A3Q2QC12
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

8078:ppm1k
gene id: 8078:ppm1k
uniprot id: A0A3Q2TJ09
names: Similarity
messages: Belongs to the PP2C family.

8078:LOC105916199
gene id: 8078:LOC105916199
uniprot id: A0A3Q2SXQ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8078:hoxd3a
gene id: 8078:hoxd3a
uniprot id: A0A3Q2QEA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8078:mns1
gene id: 8078:mns1
uniprot id: A0A3Q2TT03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

8078:tbce
gene id: 8078:tbce
uniprot id: A0A3Q2U921
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

8078:ppm1lb
gene id: 8078:ppm1lb
uniprot id: A0A3Q2QSS0
names: Similarity
messages: Belongs to the PP2C family.

8078:rack1
gene id: 8078:rack1
uniprot id: A0A3Q2T9P9
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

8078:smim22
gene id: 8078:smim22
uniprot id: A0A3Q2P7A9
names: Subcellular Location Annotation
messages: Membrane

8078:cldn1
gene id: 8078:cldn1
uniprot id: A0A3Q2PQ53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8078:ccz1
gene id: 8078:ccz1
uniprot id: A0A3Q2UMH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCZ1 family.
messages: Lysosome membrane

8078:si:ch211-282j22.3
gene id: 8078:si:ch211-282j22.3
uniprot id: A0A3Q2QLG4
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8078:ap4e1
gene id: 8078:ap4e1
uniprot id: A0A3Q2QLY7
names: Function
names: Similarity
names: Subunit
messages: AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
messages: Adaptor protein complex 4 (AP-4) is a heterotetramer composed of two large adaptins, a medium adaptin and a small adaptin.
messages: Belongs to the adaptor complexes large subunit family.

8078:ccnd2b
gene id: 8078:ccnd2b
uniprot id: A0A3Q2NSD7
uniprot id: A0A3Q2NSH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus

8078:gpbp1l1
gene id: 8078:gpbp1l1
uniprot id: A0A146P6A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

8078:bcl2l10
gene id: 8078:bcl2l10
uniprot id: A0A3Q2PJS5
names: Similarity
messages: Belongs to the Bcl-2 family.

8078:LOC105932017
gene id: 8078:LOC105932017
uniprot id: A0A3Q2QMM6
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8078:cutc
gene id: 8078:cutc
uniprot id: A0A3Q2NUY2
names: Similarity
messages: Belongs to the CutC family.

8078:dnajb12a
gene id: 8078:dnajb12a
uniprot id: A0A3Q2Q283
names: Subcellular Location Annotation
messages: Membrane

8078:ids
gene id: 8078:ids
uniprot id: A0A3Q2R1D6
names: Similarity
messages: Belongs to the sulfatase family.

8078:fgf19
gene id: 8078:fgf19
uniprot id: A0A3Q2PY93
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8078:LOC105927455
gene id: 8078:LOC105927455
uniprot id: A0A3Q2PLG5
names: Similarity
messages: Belongs to the glutamine synthetase family.

8078:cep20
gene id: 8078:cep20
uniprot id: A0A3Q2QS26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: cilium basal body

8078:cmpk2
gene id: 8078:cmpk2
uniprot id: A0A3Q2T8N2
names: Similarity
messages: Belongs to the thymidylate kinase family.

8078:si:dkey-23f9.4
gene id: 8078:si:dkey-23f9.4
uniprot id: A0A3Q2NSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

8078:fam3c
gene id: 8078:fam3c
uniprot id: A0A3Q2NVR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

8078:cd164
gene id: 8078:cd164
uniprot id: A0A3Q2Q3U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

8078:agbl5
gene id: 8078:agbl5
uniprot id: A0A146NPI0
uniprot id: A0A3Q2NYI8
uniprot id: A0A3Q2QCU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Midbody
messages: Nucleus
messages: cytosol
messages: spindle

8078:hspa8b
gene id: 8078:hspa8b
uniprot id: A0A3Q2NXR1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8078:maf1b
gene id: 8078:maf1b
uniprot id: A0A3Q2QQH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

8078:camsap1b
gene id: 8078:camsap1b
uniprot id: A0A3Q2Q8K7
uniprot id: A0A3Q2TZX5
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8078:LOC105926859
gene id: 8078:LOC105926859
uniprot id: A0A146NR17
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8078:elac2
gene id: 8078:elac2
uniprot id: A0A3Q2QRM6
names: Similarity
messages: Belongs to the RNase Z family.

8078:eftud2
gene id: 8078:eftud2
uniprot id: A0A146NNI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Nucleus

8078:ehd1a
gene id: 8078:ehd1a
uniprot id: A0A147A5Y7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8078:mutyh
gene id: 8078:mutyh
uniprot id: A0A3Q2Q6V8
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

8078:vkorc1l1
gene id: 8078:vkorc1l1
uniprot id: A0A3Q2P6Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:LOC105931093
gene id: 8078:LOC105931093
uniprot id: A0A147A245
names: Similarity
messages: Belongs to the CDK2AP family.

8078:lipca
gene id: 8078:lipca
uniprot id: A0A3Q2QW75
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:LOC105934724
gene id: 8078:LOC105934724
uniprot id: A0A3Q2Q2P3
uniprot id: A0A3Q2Q3R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

8078:etfb
gene id: 8078:etfb
uniprot id: A0A3Q2QZN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

8078:LOC105925275
gene id: 8078:LOC105925275
uniprot id: A0A3Q2PM16
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:dtx3
gene id: 8078:dtx3
uniprot id: A0A3Q2R2P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8078:rdh10a
gene id: 8078:rdh10a
uniprot id: A0A3Q2PSW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8078:LOC105933629
gene id: 8078:LOC105933629
uniprot id: A0A3Q2Q2C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

8078:zgc:162612
gene id: 8078:zgc:162612
uniprot id: A0A147A3N1
names: Subcellular Location Annotation
messages: Nucleus

8078:hibadhb
gene id: 8078:hibadhb
uniprot id: A0A146P678
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

8078:mospd1
gene id: 8078:mospd1
uniprot id: A0A3Q2QRK8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

8078:chac2
gene id: 8078:chac2
uniprot id: A0A3Q2TPL4
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

8078:aplp1
gene id: 8078:aplp1
uniprot id: A0A3Q2QND5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:soul3
gene id: 8078:soul3
uniprot id: A0A3Q2SXM9
names: Similarity
messages: Belongs to the HEBP family.

8078:slc35e3
gene id: 8078:slc35e3
uniprot id: A0A3Q2U9I6
names: Subcellular Location Annotation
messages: Membrane

8078:tecpr1b
gene id: 8078:tecpr1b
uniprot id: A0A3Q2NS34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TECPR1 family.
messages: Lysosome membrane
messages: autophagosome membrane

8078:tent5aa
gene id: 8078:tent5aa
uniprot id: A0A3Q2QGC3
names: Similarity
messages: Belongs to the TENT family.

8078:erg28
gene id: 8078:erg28
uniprot id: A0A146P8E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:tmem86a
gene id: 8078:tmem86a
uniprot id: A0A3Q2QJT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

8078:LOC105934024
gene id: 8078:LOC105934024
uniprot id: A0A3Q2NU87
names: Similarity
messages: Belongs to the mTERF family.

8078:hmmr
gene id: 8078:hmmr
uniprot id: A0A3Q2Q1R6
names: Subcellular Location Annotation
messages: spindle

8078:drd2l
gene id: 8078:drd2l
uniprot id: A0A3Q2U6X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:elp6
gene id: 8078:elp6
uniprot id: A0A146P9Y3
names: Similarity
messages: Belongs to the ELP6 family.

8078:cfap410
gene id: 8078:cfap410
uniprot id: A0A147A2P1
names: Similarity
messages: Belongs to the SDS22 family.

8078:shbg
gene id: 8078:shbg
uniprot id: A0A3Q2NPU9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:ran
gene id: 8078:ran
uniprot id: A0A3Q2PL99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

8078:LOC105935265
gene id: 8078:LOC105935265
uniprot id: A0A3Q2NYE1
names: Similarity
messages: Belongs to the OSBP family.

8078:LOC105915474
gene id: 8078:LOC105915474
uniprot id: A0A147A5P9
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

8078:LOC105925725
gene id: 8078:LOC105925725
uniprot id: A0A3Q2PT18
names: Similarity
messages: Belongs to the NKAP family.

8078:six6a
gene id: 8078:six6a
uniprot id: A0A3Q2QEP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

8078:dio2
gene id: 8078:dio2
uniprot id: P79747
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iodothyronine deiodinase family.
messages: Membrane
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.

8078:LOC105918739
gene id: 8078:LOC105918739
uniprot id: A0A3Q2PEE7
names: Similarity
messages: Belongs to the methyltransferase superfamily.

8078:f11r.1
gene id: 8078:f11r.1
uniprot id: A0A3Q2Q7U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily.
messages: Cell membrane
messages: Membrane
messages: tight junction

8078:irf4a
gene id: 8078:irf4a
uniprot id: A0A3Q2UHD8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:dusp4
gene id: 8078:dusp4
uniprot id: A0A3Q2QL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

8078:kiaa1191
gene id: 8078:kiaa1191
uniprot id: A0A146P2S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P33MONOX family.
messages: Cytoplasm

8078:plpbp
gene id: 8078:plpbp
uniprot id: A0A3Q2QN12
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

8078:fbxo31
gene id: 8078:fbxo31
uniprot id: A0A146P6Q5
names: Similarity
names: Subunit
messages: Belongs to the FBXO31 family.
messages: Part of a SCF (SKP1-cullin-F-box) protein ligase complex.

8078:LOC105939507
gene id: 8078:LOC105939507
uniprot id: A0A146ZJJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

8078:eed
gene id: 8078:eed
uniprot id: A0A3Q2QTH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ESC family.
messages: Nucleus

8078:ccnk
gene id: 8078:ccnk
uniprot id: A0A3Q2SW04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8078:spi1a
gene id: 8078:spi1a
uniprot id: A0A3Q2PC66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:parp2
gene id: 8078:parp2
uniprot id: A0A3Q2UQX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

8078:LOC105916840
gene id: 8078:LOC105916840
uniprot id: A0A3Q2QXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8078:LOC105926698
gene id: 8078:LOC105926698
uniprot id: A0A3Q2Q862
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8078:ipo9
gene id: 8078:ipo9
uniprot id: A0A146VIV1
names: Subcellular Location Annotation
messages: Cytoplasm

8078:LOC105927172
gene id: 8078:LOC105927172
uniprot id: A0A3Q2P087
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

8078:ppp1r14bb
gene id: 8078:ppp1r14bb
uniprot id: A0A3Q2P9K3
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8078:hhex
gene id: 8078:hhex
uniprot id: A0A146P4P7
names: Subcellular Location Annotation
messages: Nucleus

8078:hoxc5a
gene id: 8078:hoxc5a
uniprot id: A0A146WMM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8078:sf3b1
gene id: 8078:sf3b1
uniprot id: A0A3Q2PJ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

8078:si:ch73-374l24.1
gene id: 8078:si:ch73-374l24.1
uniprot id: A0A3Q2UGX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane

8078:pim2
gene id: 8078:pim2
uniprot id: A0A147APH5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8078:LOC105936346
gene id: 8078:LOC105936346
uniprot id: A0A3Q2NSC5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:s100z
gene id: 8078:s100z
uniprot id: A0A3Q2NZM5
names: Similarity
messages: Belongs to the S-100 family.

8078:marcksb
gene id: 8078:marcksb
uniprot id: A0A3Q2QJT1
names: Similarity
messages: Belongs to the MARCKS family.

8078:ap1m1
gene id: 8078:ap1m1
uniprot id: A0A3Q2U9X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

8078:LOC105919158
gene id: 8078:LOC105919158
uniprot id: A0A146P5Z1
names: Subcellular Location Annotation
messages: Membrane

8078:ndufb5
gene id: 8078:ndufb5
uniprot id: A0A3Q2P3Y3
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB5 subunit family.
messages: Complex I is composed of 45 different subunits.

8078:LOC105935766
gene id: 8078:LOC105935766
uniprot id: A0A3Q2Q7P6
names: Similarity
messages: Belongs to the SELO family.

8078:cdc6
gene id: 8078:cdc6
uniprot id: A0A146WBX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
messages: Nucleus

8078:kbtbd8
gene id: 8078:kbtbd8
uniprot id: A0A147AB85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

8078:LOC105916761
gene id: 8078:LOC105916761
uniprot id: A0A3Q2Q333
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8078:LOC105920159
gene id: 8078:LOC105920159
uniprot id: A0A3Q2QF78
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

8078:sypl2b
gene id: 8078:sypl2b
uniprot id: A0A3Q2QA50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8078:slc25a15a
gene id: 8078:slc25a15a
uniprot id: A0A3Q2PHA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:gsr
gene id: 8078:gsr
uniprot id: A0A146QZD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

8078:akr1a1b
gene id: 8078:akr1a1b
uniprot id: A0A3Q2QP76
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8078:LOC105938329
gene id: 8078:LOC105938329
uniprot id: A0A3Q2QS74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

8078:LOC105932604
gene id: 8078:LOC105932604
uniprot id: A0A3Q2UKP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

8078:uros
gene id: 8078:uros
uniprot id: A0A3Q2PCK1
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

8078:tpra1
gene id: 8078:tpra1
uniprot id: A0A3Q2P3F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

8078:angptl4
gene id: 8078:angptl4
uniprot id: A0A3Q2NZC6
names: Subcellular Location Annotation
messages: Secreted

8078:tsen34
gene id: 8078:tsen34
uniprot id: A0A147AMQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

8078:LOC105924246
gene id: 8078:LOC105924246
uniprot id: A0A3Q2PFI4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

8078:mmaa
gene id: 8078:mmaa
uniprot id: A0A3Q2P3V1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

8078:si:dkey-57a22.15
gene id: 8078:si:dkey-57a22.15
uniprot id: A0A3Q2SXS7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8078:ldlrad3
gene id: 8078:ldlrad3
uniprot id: A0A3Q2QJV1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:zic6
gene id: 8078:zic6
uniprot id: A0A147ABT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

8078:st8sia2
gene id: 8078:st8sia2
uniprot id: A0A3Q2QFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8078:mpp6a
gene id: 8078:mpp6a
uniprot id: A0A146X5C5
names: Similarity
messages: Belongs to the MAGUK family.

8078:cab39l1
gene id: 8078:cab39l1
uniprot id: A0A147A4X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

8078:cnr1
gene id: 8078:cnr1
uniprot id: A0A146ZKY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids. Mediates many cannabinoid-induced effects in the central nervous system (CNS), as well as in peripheral tissues. Signaling typically involves reduction in cyclic AMP.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

8078:LOC105934853
gene id: 8078:LOC105934853
uniprot id: A0A146VRA6
names: Similarity
messages: Belongs to the intermediate filament family.

8078:cart4
gene id: 8078:cart4
uniprot id: A0A146ZMW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8078:LOC105931135
gene id: 8078:LOC105931135
uniprot id: A0A3Q2QE96
names: Similarity
messages: Belongs to the cornifelin family.

8078:tyw3
gene id: 8078:tyw3
uniprot id: A0A3Q2Q6D8
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

8078:snx25
gene id: 8078:snx25
uniprot id: A0A146NCC4
names: Similarity
messages: Belongs to the sorting nexin family.

8078:LOC105916435
gene id: 8078:LOC105916435
uniprot id: A0A3Q2QQD9
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8078:becn1
gene id: 8078:becn1
uniprot id: A0A3Q2P973
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beclin family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Mitochondrion membrane
messages: Plays a central role in autophagy.
messages: autophagosome
messages: trans-Golgi network membrane

8078:med24
gene id: 8078:med24
uniprot id: A0A3Q2PE51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

8078:anapc11
gene id: 8078:anapc11
uniprot id: A0A3Q2TZJ3
names: Similarity
messages: Belongs to the RING-box family.

8078:ndrg1a
gene id: 8078:ndrg1a
uniprot id: A0A3Q2NMD9
names: Similarity
messages: Belongs to the NDRG family.

8078:med20
gene id: 8078:med20
uniprot id: A0A147A8Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8078:tpk1
gene id: 8078:tpk1
uniprot id: A0A3Q2Q991
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

8078:tmem47
gene id: 8078:tmem47
uniprot id: A0A3Q2P372
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8078:utp11
gene id: 8078:utp11
uniprot id: A0A3Q2QW56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

8078:LOC105921473
gene id: 8078:LOC105921473
uniprot id: A0A3Q2UQL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

8078:slc35a3b
gene id: 8078:slc35a3b
uniprot id: A0A3Q2PR65
uniprot id: A0A3Q2UK48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

8078:rtcb
gene id: 8078:rtcb
uniprot id: A0A3Q2P827
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

8078:usp16
gene id: 8078:usp16
uniprot id: A0A3Q2QD72
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. USP16 subfamily.
messages: Homotetramer.
messages: Nucleus
messages: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
messages: The UBP-type zinc finger binds 3 zinc ions that form a pair of cross-braced ring fingers encapsulated within a third zinc finger in the primary structure. It recognizes the C-terminal tail of free ubiquitin.

8078:rev3l
gene id: 8078:rev3l
uniprot id: A0A146TAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

8078:dpy19l3
gene id: 8078:dpy19l3
uniprot id: A0A3Q2TKU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

8078:sec22c
gene id: 8078:sec22c
uniprot id: A0A3Q2PG66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

8078:LOC105940172
gene id: 8078:LOC105940172
uniprot id: A0A3Q2PRS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8078:LOC105926182
gene id: 8078:LOC105926182
uniprot id: A0A3Q2Q1F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
messages: Mitochondrion outer membrane

8078:gpam
gene id: 8078:gpam
uniprot id: A0A3Q2TE34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
messages: Mitochondrion outer membrane

8078:nuf2
gene id: 8078:nuf2
uniprot id: A0A3Q2QKH8
names: Similarity
messages: Belongs to the NUF2 family.

8078:b3galt6
gene id: 8078:b3galt6
uniprot id: A0A3Q2NZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:nampt1
gene id: 8078:nampt1
uniprot id: A0A3Q2QGT8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

8078:hoxa11b
gene id: 8078:hoxa11b
uniprot id: A0A3Q2PKH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8078:washc5
gene id: 8078:washc5
uniprot id: A0A3Q2Q934
names: Similarity
messages: Belongs to the strumpellin family.

8078:amigo1
gene id: 8078:amigo1
uniprot id: A0A3Q2QA52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

8078:gnb1b
gene id: 8078:gnb1b
uniprot id: A0A146VWZ2
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8078:fam131a
gene id: 8078:fam131a
uniprot id: A0A3Q2UR11
names: Similarity
messages: Belongs to the FAM131 family.

8078:LOC105915535
gene id: 8078:LOC105915535
uniprot id: A0A147AZZ3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8078:mapk1
gene id: 8078:mapk1
uniprot id: A0A3Q2PGS7
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8078:tada2a
gene id: 8078:tada2a
uniprot id: A0A147AY78
names: Subcellular Location Annotation
messages: Nucleus

8078:acadl
gene id: 8078:acadl
uniprot id: A0A3Q2P6F0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Homotetramer.
messages: Mitochondrion matrix

8078:mapk12a
gene id: 8078:mapk12a
uniprot id: A0A3Q2PE60
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8078:taf10
gene id: 8078:taf10
uniprot id: A0A3Q2NQN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus
messages: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.

8078:pdpr
gene id: 8078:pdpr
uniprot id: A0A3Q2Q5U5
names: Similarity
messages: Belongs to the GcvT family.

8078:cntnap1
gene id: 8078:cntnap1
uniprot id: A0A147B122
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:vps45
gene id: 8078:vps45
uniprot id: A0A3Q2PNG0
uniprot id: A0A3Q2PPK4
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8078:tada1
gene id: 8078:tada1
uniprot id: A0A146P5K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TADA1 family.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

8078:LOC105933336
gene id: 8078:LOC105933336
uniprot id: A0A3Q2UB15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
messages: Belongs to the actin family. ARP2 subfamily.
messages: Component of the Arp2/3 complex.
messages: cytoskeleton

8078:polr3d
gene id: 8078:polr3d
uniprot id: A0A146X264
names: Subcellular Location Annotation
messages: Nucleus

8078:arsj
gene id: 8078:arsj
uniprot id: A0A146RXL5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8078:vax2
gene id: 8078:vax2
uniprot id: A0A147ABT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMX homeobox family.
messages: Nucleus

8078:tmem41aa
gene id: 8078:tmem41aa
uniprot id: A0A3Q2QEX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

8078:tnfsf12
gene id: 8078:tnfsf12
uniprot id: A0A3Q2QTM3
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8078:tmem198b
gene id: 8078:tmem198b
uniprot id: A0A146YPZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

8078:LOC105936323
gene id: 8078:LOC105936323
uniprot id: A0A3Q2Q9A5
names: Function
names: Similarity
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

8078:clic1
gene id: 8078:clic1
uniprot id: A0A146MWK8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8078:mrpl11
gene id: 8078:mrpl11
uniprot id: A0A3Q2TE86
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

8078:wnt6b
gene id: 8078:wnt6b
uniprot id: A0A3Q2QC98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8078:mtfr1l
gene id: 8078:mtfr1l
uniprot id: A0A147AR44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

8078:hs3st3b1a
gene id: 8078:hs3st3b1a
uniprot id: A0A3Q2QMN2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8078:LOC105930200
gene id: 8078:LOC105930200
uniprot id: A0A3Q2QZ28
names: Similarity
messages: Belongs to the peptidase C2 family.

8078:prdx2
gene id: 8078:prdx2
uniprot id: A0A3Q2PJP8
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

8078:c7h2orf49
gene id: 8078:c7h2orf49
uniprot id: A0A3Q2PFD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

8078:LOC105934206
gene id: 8078:LOC105934206
uniprot id: A0A3Q2PVB0
names: Similarity
messages: Belongs to the acid ceramidase family.

8078:LOC105932988
gene id: 8078:LOC105932988
uniprot id: A0A3Q2SRS4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8078:cct6a
gene id: 8078:cct6a
uniprot id: A0A3Q2R409
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8078:zdhhc23b
gene id: 8078:zdhhc23b
uniprot id: A0A3Q2PRW0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8078:si:ch73-206p6.1
gene id: 8078:si:ch73-206p6.1
uniprot id: A0A147AUE2
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

8078:yipf6
gene id: 8078:yipf6
uniprot id: A0A3Q2QXC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

8078:cdc42se1
gene id: 8078:cdc42se1
uniprot id: A0A3Q2UJE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

8078:usp44
gene id: 8078:usp44
uniprot id: A0A3Q2NTQ4
names: Similarity
messages: Belongs to the peptidase C19 family.

8078:LOC105917811
gene id: 8078:LOC105917811
uniprot id: A0A3Q2P0H0
names: Similarity
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

8078:si:ch211-225p5.8
gene id: 8078:si:ch211-225p5.8
uniprot id: A0A3Q2Q2X7
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105930245
gene id: 8078:LOC105930245
uniprot id: A0A3Q2PVR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:frzb
gene id: 8078:frzb
uniprot id: A0A3Q2U9W5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

8078:LOC105940239
gene id: 8078:LOC105940239
uniprot id: A0A3Q2Q6S7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

8078:LOC105939499
gene id: 8078:LOC105939499
uniprot id: A0A146ZKS7
names: Similarity
messages: Belongs to the SNF7 family.

8078:mst1
gene id: 8078:mst1
uniprot id: A0A3Q2PXJ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8078:LOC105931269
gene id: 8078:LOC105931269
uniprot id: A0A147A0W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

8078:coq6
gene id: 8078:coq6
uniprot id: A0A3Q2PP29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

8078:LOC105927615
gene id: 8078:LOC105927615
uniprot id: A0A3Q2QRN3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:LOC118556010
gene id: 8078:LOC118556010
uniprot id: A0A3Q2U429
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:LOC105932439
gene id: 8078:LOC105932439
uniprot id: A0A3Q2PZQ9
names: Subcellular Location Annotation
messages: extracellular space

8078:arrdc1a
gene id: 8078:arrdc1a
uniprot id: A0A3Q2UC93
names: Similarity
messages: Belongs to the arrestin family.

8078:dock4b
gene id: 8078:dock4b
uniprot id: A0A3Q2NMF9
names: Similarity
messages: Belongs to the DOCK family.

8078:si:ch1073-280e3.1
gene id: 8078:si:ch1073-280e3.1
uniprot id: A0A3Q2QT83
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8078:pts
gene id: 8078:pts
uniprot id: A0A146P4L4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

8078:fgfr1a
gene id: 8078:fgfr1a
uniprot id: A0A3Q2NNK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Nucleus
messages: Vesicle
messages: cytosol

8078:hs2st1b
gene id: 8078:hs2st1b
uniprot id: A0A146RSA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

8078:nek7
gene id: 8078:nek7
uniprot id: A0A3Q2P1P1
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:LOC105929126
gene id: 8078:LOC105929126
uniprot id: A0A146WLC6
names: Similarity
messages: Belongs to the OSBP family.

8078:LOC105939462
gene id: 8078:LOC105939462
uniprot id: A0A3Q2PX88
uniprot id: A0A3Q2PYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:LOC105920196
gene id: 8078:LOC105920196
uniprot id: A0A3Q2U3F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS26 family.
messages: Mitochondrion

8078:ubxn1
gene id: 8078:ubxn1
uniprot id: A0A3Q2SRC8
names: Subcellular Location Annotation
messages: Cytoplasm

8078:cops2
gene id: 8078:cops2
uniprot id: A0A3Q2NRV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN2 family.
messages: Cytoplasm
messages: Nucleus

8078:ca14
gene id: 8078:ca14
uniprot id: A0A3Q2Q1T3
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

8078:mbtd1
gene id: 8078:mbtd1
uniprot id: A0A146VKW7
uniprot id: A0A3Q2NTS3
names: Subcellular Location Annotation
messages: Nucleus

8078:oxa1l
gene id: 8078:oxa1l
uniprot id: A0A3Q2QU72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

8078:hspd1
gene id: 8078:hspd1
uniprot id: A0A3Q2PHR8
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

8078:LOC105936286
gene id: 8078:LOC105936286
uniprot id: A0A146VHG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

8078:clrn2
gene id: 8078:clrn2
uniprot id: A0A3Q2U9U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

8078:LOC105928200
gene id: 8078:LOC105928200
uniprot id: A0A3Q2Q098
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8078:zgc:123305
gene id: 8078:zgc:123305
uniprot id: A0A3Q2P465
names: Similarity
messages: Belongs to the lipin family.

8078:dna2
gene id: 8078:dna2
uniprot id: A0A3Q2PBZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Mitochondrion
messages: Nucleus

8078:rab3c
gene id: 8078:rab3c
uniprot id: A0A3Q2QVJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

8078:LOC105934594
gene id: 8078:LOC105934594
uniprot id: A0A146MV12
names: Similarity
messages: Belongs to the SPIN/STSY family.

8078:otx1
gene id: 8078:otx1
uniprot id: A0A146ZX27
names: Subcellular Location Annotation
messages: Nucleus

8078:zgc:113425
gene id: 8078:zgc:113425
uniprot id: A0A3Q2P2J1
names: Similarity
messages: Belongs to the MS4A family.

8078:mat1a
gene id: 8078:mat1a
uniprot id: A0A3Q2Q592
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

8078:LOC105940262
gene id: 8078:LOC105940262
uniprot id: A0A3Q2SP58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:uts1
gene id: 8078:uts1
uniprot id: A0A3Q2T4R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

8078:lrp13
gene id: 8078:lrp13
uniprot id: A0A3Q2QC91
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:ppm1ba
gene id: 8078:ppm1ba
uniprot id: A0A3Q2PVN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8078:ddb2
gene id: 8078:ddb2
uniprot id: A0A3Q2TRK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

8078:LOC105929743
gene id: 8078:LOC105929743
uniprot id: A0A146WKL4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8078:fam32a
gene id: 8078:fam32a
uniprot id: A0A3Q2NW28
names: Similarity
messages: Belongs to the FAM32 family.

8078:znf408
gene id: 8078:znf408
uniprot id: A0A146ZL74
names: Subcellular Location Annotation
messages: Nucleus

8078:lgmn
gene id: 8078:lgmn
uniprot id: A0A3Q2QBU2
names: Similarity
messages: Belongs to the peptidase C13 family.

8078:LOC105926744
gene id: 8078:LOC105926744
uniprot id: A0A146P478
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8078:LOC105938070
gene id: 8078:LOC105938070
uniprot id: A0A3Q2P1H9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:LOC105926735
gene id: 8078:LOC105926735
uniprot id: A0A3Q2TRP7
uniprot id: A0A3Q2TRQ2
names: Similarity
messages: Belongs to the FAM131 family.

8078:LOC105933848
gene id: 8078:LOC105933848
uniprot id: A0A146ZVV5
names: Subcellular Location Annotation
messages: Membrane

8078:hspa4a
gene id: 8078:hspa4a
uniprot id: A0A3Q2U1X0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8078:zgc:109982
gene id: 8078:zgc:109982
uniprot id: A0A3Q2PC26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

8078:mrps33
gene id: 8078:mrps33
uniprot id: A0A3Q2QJM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

8078:LOC105937628
gene id: 8078:LOC105937628
uniprot id: A0A3Q2PWM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:ggps1
gene id: 8078:ggps1
uniprot id: A0A3Q2NUJ6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8078:LOC105936132
gene id: 8078:LOC105936132
uniprot id: A0A3Q2PA01
uniprot id: A0A3Q2T402
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

8078:toe1
gene id: 8078:toe1
uniprot id: A0A3Q2Q168
names: Similarity
messages: Belongs to the CAF1 family.

8078:si:ch211-107n13.1
gene id: 8078:si:ch211-107n13.1
uniprot id: A0A146ZUR5
names: Similarity
messages: Belongs to the FAM110 family.

8078:dync1li1
gene id: 8078:dync1li1
uniprot id: A0A146VA31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

8078:smarca5
gene id: 8078:smarca5
uniprot id: A0A3Q2QEF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

8078:LOC105933007
gene id: 8078:LOC105933007
uniprot id: A0A3Q2NS80
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8078:tph1a
gene id: 8078:tph1a
uniprot id: A0A3Q2QLB5
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

8078:cltcl1
gene id: 8078:cltcl1
uniprot id: A0A3Q2P2C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

8078:LOC105927790
gene id: 8078:LOC105927790
uniprot id: A0A147A7V7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

8078:lrp4
gene id: 8078:lrp4
uniprot id: A0A147A0L2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:get1
gene id: 8078:get1
uniprot id: A0A3Q2TDQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:sept8a
gene id: 8078:sept8a
uniprot id: A0A3Q2NVV6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8078:LOC105926937
gene id: 8078:LOC105926937
uniprot id: A0A147A9G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCHP family.
messages: cytoskeleton

8078:gpt2l
gene id: 8078:gpt2l
uniprot id: A0A3Q2PSW4
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

8078:slc6a15
gene id: 8078:slc6a15
uniprot id: A0A147B2W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8078:lgals3a
gene id: 8078:lgals3a
uniprot id: A0A3Q2NUP0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

8078:cwf19l2
gene id: 8078:cwf19l2
uniprot id: A0A3Q2ST19
names: Similarity
messages: Belongs to the CWF19 family.

8078:csrnp2
gene id: 8078:csrnp2
uniprot id: A0A3Q2P1M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8078:camsap1a
gene id: 8078:camsap1a
uniprot id: A0A3Q2P430
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8078:cdc123
gene id: 8078:cdc123
uniprot id: A0A147AWY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

8078:zgc:162297
gene id: 8078:zgc:162297
uniprot id: A0A3Q2ULT1
names: Similarity
messages: Belongs to the BtpA family.

8078:mogs
gene id: 8078:mogs
uniprot id: A0A3Q2R340
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

8078:dcaf11
gene id: 8078:dcaf11
uniprot id: A0A3Q2SZD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat LEC14B family.
messages: Interacts with DDB1 and CUL4A.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

8078:grpr
gene id: 8078:grpr
uniprot id: A0A3Q2P8T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:LOC105935154
gene id: 8078:LOC105935154
uniprot id: A0A3Q2U7L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

8078:nr0b1
gene id: 8078:nr0b1
uniprot id: A0A3Q2PDC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

8078:LOC105916535
gene id: 8078:LOC105916535
uniprot id: A0A3Q2PUE1
uniprot id: A0A3Q2QYT7
names: Subcellular Location Annotation
messages: Membrane

8078:si:ch211-247n2.1
gene id: 8078:si:ch211-247n2.1
uniprot id: A0A3Q2PER8
names: Subcellular Location Annotation
messages: Membrane

8078:hdgfl2
gene id: 8078:hdgfl2
uniprot id: A0A3Q2NV97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

8078:s1pr5a
gene id: 8078:s1pr5a
uniprot id: A0A3Q2QJ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8078:tmem144b
gene id: 8078:tmem144b
uniprot id: A0A146ZR25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

8078:egr2b
gene id: 8078:egr2b
uniprot id: A0A146ZI36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

8078:iah1
gene id: 8078:iah1
uniprot id: A0A3Q2P2Z6
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

8078:manea
gene id: 8078:manea
uniprot id: A0A3Q2TMY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:fgf23
gene id: 8078:fgf23
uniprot id: A0A3Q2SRF6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8078:exoc8
gene id: 8078:exoc8
uniprot id: A0A3Q2PL17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: growth cone
messages: perinuclear region

8078:LOC105939139
gene id: 8078:LOC105939139
uniprot id: A0A3Q2U4Q8
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105920697
gene id: 8078:LOC105920697
uniprot id: A0A3Q2U3V8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:mthfd1b
gene id: 8078:mthfd1b
uniprot id: A0A146YHL0
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

8078:mrps15
gene id: 8078:mrps15
uniprot id: A0A3Q2Q4I9
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

8078:mis12
gene id: 8078:mis12
uniprot id: A0A3Q2PA28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mis12 family.
messages: kinetochore

8078:adss2
gene id: 8078:adss2
uniprot id: A0A147A7I1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

8078:hspa14
gene id: 8078:hspa14
uniprot id: A0A3Q2PB96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Component of ribosome-associated complex (RAC), a heterodimer composed of Hsp70/DnaK-type chaperone HSPA14 and Hsp40/DnaJ-type chaperone DNAJC2.
messages: Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity.
messages: cytosol

8078:LOC105937401
gene id: 8078:LOC105937401
uniprot id: A0A146ZPR2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8078:letmd1
gene id: 8078:letmd1
uniprot id: A0A3Q2NZN3
names: Subcellular Location Annotation
messages: Membrane

8078:slc26a2
gene id: 8078:slc26a2
uniprot id: A0A3Q2PII8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sulfate transporter. May play a role in endochondral bone formation.

8078:arrdc3b
gene id: 8078:arrdc3b
uniprot id: A0A3Q2NUJ2
names: Similarity
messages: Belongs to the arrestin family.

8078:b3gnt9
gene id: 8078:b3gnt9
uniprot id: A0A147AN14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:sbk3
gene id: 8078:sbk3
uniprot id: A0A3Q2PN18
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:sesn2
gene id: 8078:sesn2
uniprot id: A0A3Q2QG64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

8078:hnf1a
gene id: 8078:hnf1a
uniprot id: A0A3Q2Q3G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

8078:peli3
gene id: 8078:peli3
uniprot id: A0A3Q2PKS0
names: Similarity
messages: Belongs to the pellino family.

8078:LOC105932083
gene id: 8078:LOC105932083
uniprot id: A0A3Q2QMM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

8078:e2f1
gene id: 8078:e2f1
uniprot id: A0A147ABI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8078:gucy1a2
gene id: 8078:gucy1a2
uniprot id: A0A147AHR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

8078:LOC105929719
gene id: 8078:LOC105929719
uniprot id: A0A3Q2TDB8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:LOC105940153
gene id: 8078:LOC105940153
uniprot id: A0A3Q2SSG3
names: Subcellular Location Annotation
messages: Membrane

8078:serpinf2b
gene id: 8078:serpinf2b
uniprot id: A0A3Q2NTZ8
names: Similarity
messages: Belongs to the serpin family.

8078:sfrp5
gene id: 8078:sfrp5
uniprot id: A0A3Q2NR37
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105915649
gene id: 8078:LOC105915649
uniprot id: A0A3Q2R314
names: Similarity
messages: Belongs to the CCDC149 family.

8078:LOC105919682
gene id: 8078:LOC105919682
uniprot id: A0A147B4K3
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm

8078:cxcl19
gene id: 8078:cxcl19
uniprot id: A0A3Q2PSZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

8078:lrrc4cb
gene id: 8078:lrrc4cb
uniprot id: A0A147B4N7
names: Subcellular Location Annotation
messages: Membrane

8078:mapkapk3
gene id: 8078:mapkapk3
uniprot id: A0A3Q2NZJ0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:LOC105918337
gene id: 8078:LOC105918337
uniprot id: A0A3Q2QE87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8078:ctsl
gene id: 8078:ctsl
uniprot id: Q6XRF7
names: Similarity
messages: Belongs to the peptidase C1 family.

8078:ovca2
gene id: 8078:ovca2
uniprot id: A0A3Q2PGU4
names: Similarity
messages: Belongs to the LovG family.

8078:ctnnb1
gene id: 8078:ctnnb1
uniprot id: A0A3Q2PQH5
names: Similarity
messages: Belongs to the beta-catenin family.

8078:ciao2b
gene id: 8078:ciao2b
uniprot id: A0A3Q2QKS4
names: Similarity
messages: Belongs to the MIP18 family.

8078:LOC105929560
gene id: 8078:LOC105929560
uniprot id: A0A3Q2SNW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

8078:s1pr5b
gene id: 8078:s1pr5b
uniprot id: A0A146P5C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8078:mag
gene id: 8078:mag
uniprot id: A0A146ZJ29
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105916730
gene id: 8078:LOC105916730
uniprot id: A0A3Q2NW14
names: Subcellular Location Annotation
messages: Membrane

8078:prdm1a
gene id: 8078:prdm1a
uniprot id: A0A146YZQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

8078:LOC105933672
gene id: 8078:LOC105933672
uniprot id: A0A147B1Q1
names: Similarity
messages: Belongs to the PACS family.

8078:eif5
gene id: 8078:eif5
uniprot id: A0A146ZTL3
names: Function
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).

8078:ints9
gene id: 8078:ints9
uniprot id: A0A3Q2Q3P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

8078:tpd52l2b
gene id: 8078:tpd52l2b
uniprot id: A0A3Q2PMT7
uniprot id: A0A3Q2PMU7
uniprot id: A0A3Q2QUJ9
names: Similarity
messages: Belongs to the TPD52 family.

8078:narf
gene id: 8078:narf
uniprot id: A0A3Q2PRT6
names: Similarity
messages: Belongs to the NARF family.

8078:pacs2
gene id: 8078:pacs2
uniprot id: A0A3Q2Q9W6
uniprot id: A0A3Q2STK1
names: Similarity
messages: Belongs to the PACS family.

8078:LOC105933580
gene id: 8078:LOC105933580
uniprot id: A0A3Q2SSN8
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

8078:zgc:91976
gene id: 8078:zgc:91976
uniprot id: A0A146P6B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

8078:tmem53
gene id: 8078:tmem53
uniprot id: A0A3Q2Q166
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

8078:napsa
gene id: 8078:napsa
uniprot id: A0A3Q2QBQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

8078:LOC105915840
gene id: 8078:LOC105915840
uniprot id: A0A147B075
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: centrosome
messages: spindle pole

8078:tbx15
gene id: 8078:tbx15
uniprot id: A0A146ZLR0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:hal
gene id: 8078:hal
uniprot id: A0A3Q2QE42
names: Similarity
messages: Belongs to the PAL/histidase family.

8078:dkc1
gene id: 8078:dkc1
uniprot id: A0A146V763
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

8078:pip4p2
gene id: 8078:pip4p2
uniprot id: A0A3Q2PFQ6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8078:loxl3b
gene id: 8078:loxl3b
uniprot id: A0A146Y163
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8078:gpc4
gene id: 8078:gpc4
uniprot id: A0A3Q2PNN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

8078:pigg
gene id: 8078:pigg
uniprot id: A0A147A567
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:LOC105926390
gene id: 8078:LOC105926390
uniprot id: A0A3Q2THZ6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:utp23
gene id: 8078:utp23
uniprot id: A0A3Q2P5G0
names: Subcellular Location Annotation
messages: nucleolus

8078:ccnd1
gene id: 8078:ccnd1
uniprot id: A0A146Y9P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus

8078:LOC105923741
gene id: 8078:LOC105923741
uniprot id: A0A3Q2QFP4
names: Similarity
messages: Belongs to the ARTD/PARP family.

8078:imp4
gene id: 8078:imp4
uniprot id: A0A3Q2UQ49
names: Subcellular Location Annotation
messages: nucleolus

8078:atp13a2
gene id: 8078:atp13a2
uniprot id: A0A3Q2PEU4
uniprot id: A0A3Q2QNN6
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

8078:pnp5a
gene id: 8078:pnp5a
uniprot id: A0A146P745
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

8078:LOC105930913
gene id: 8078:LOC105930913
uniprot id: A0A3Q2QRB2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8078:tmem35
gene id: 8078:tmem35
uniprot id: A0A3Q2PPT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

8078:prdm1c
gene id: 8078:prdm1c
uniprot id: A0A3Q2Q2G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

8078:anapc16
gene id: 8078:anapc16
uniprot id: A0A147B5W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

8078:postnb
gene id: 8078:postnb
uniprot id: A0A3Q2QGG8
names: Subcellular Location Annotation
messages: extracellular matrix

8078:ppil4
gene id: 8078:ppil4
uniprot id: A0A146P4M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8078:LOC105931695
gene id: 8078:LOC105931695
uniprot id: A0A3Q2P373
names: Subcellular Location Annotation
messages: Nucleus

8078:march9
gene id: 8078:march9
uniprot id: A0A3Q2PC39
names: Subcellular Location Annotation
messages: Membrane

8078:c13h18orf21
gene id: 8078:c13h18orf21
uniprot id: A0A146ZNF8
names: Similarity
messages: Belongs to the UPF0711 family.

8078:bmp1a
gene id: 8078:bmp1a
uniprot id: A0A3Q2UMH0
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105925986
gene id: 8078:LOC105925986
uniprot id: A0A3Q2U7B7
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

8078:max
gene id: 8078:max
uniprot id: A0A3Q2P8P4
uniprot id: A0A3Q2QH48
uniprot id: A0A3Q2QI29
names: Similarity
messages: Belongs to the MAX family.

8078:cmtm6
gene id: 8078:cmtm6
uniprot id: A0A3Q2R012
names: Subcellular Location Annotation
messages: Membrane

8078:nrp2a
gene id: 8078:nrp2a
uniprot id: A0A147AMC7
uniprot id: A0A3Q2UNI9
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:glod4
gene id: 8078:glod4
uniprot id: A0A3Q2NTE0
names: Similarity
messages: Belongs to the glyoxalase I family.

8078:kif11
gene id: 8078:kif11
uniprot id: A0A3Q2P1B0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8078:gart
gene id: 8078:gart
uniprot id: A0A3Q2QYK5
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

8078:fth1b
gene id: 8078:fth1b
uniprot id: A0A146P870
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8078:LOC105920901
gene id: 8078:LOC105920901
uniprot id: A0A3Q2PYG5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8078:ulk3
gene id: 8078:ulk3
uniprot id: A0A3Q2QI31
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:has2
gene id: 8078:has2
uniprot id: A0A3Q2QFC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NodC/HAS family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane

8078:ctdp1
gene id: 8078:ctdp1
uniprot id: A0A146ZSK2
names: Subcellular Location Annotation
messages: Nucleus

8078:nr1d4a
gene id: 8078:nr1d4a
uniprot id: A0A3Q2TW70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8078:rplp2
gene id: 8078:rplp2
uniprot id: A0A147A816
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Heterodimer with RPLP1 at the lateral ribosomal stalk of the large ribosomal subunit.
messages: Plays an important role in the elongation step of protein synthesis.

8078:fynb
gene id: 8078:fynb
uniprot id: A0A3Q2PAZ4
uniprot id: A0A3Q2PBH3
uniprot id: A0A3Q2PCM5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8078:suds3
gene id: 8078:suds3
uniprot id: A0A146P6X2
names: Subcellular Location Annotation
messages: Nucleus

8078:bpgm
gene id: 8078:bpgm
uniprot id: A0A3Q2P0M9
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

8078:tmbim1a
gene id: 8078:tmbim1a
uniprot id: A0A3Q2PTK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8078:naalad2
gene id: 8078:naalad2
uniprot id: A0A146XG42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

8078:LOC105934677
gene id: 8078:LOC105934677
uniprot id: A0A3Q2TXD6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8078:rapsn
gene id: 8078:rapsn
uniprot id: A0A147B2Y9
names: Similarity
messages: Belongs to the RAPsyn family.

8078:stip1
gene id: 8078:stip1
uniprot id: A0A3Q2QCY7
names: Subcellular Location Annotation
messages: Cytoplasm

8078:dhrs11a
gene id: 8078:dhrs11a
uniprot id: A0A3Q2T7V3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:cfap97
gene id: 8078:cfap97
uniprot id: A0A3Q2R3J7
names: Similarity
messages: Belongs to the CFAP97 family.

8078:pkd2
gene id: 8078:pkd2
uniprot id: A0A146YVX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Cell membrane
messages: Membrane
messages: cilium membrane

8078:alg8
gene id: 8078:alg8
uniprot id: A0A3Q2QCH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:vat1
gene id: 8078:vat1
uniprot id: A0A3Q2QPY9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8078:coro1a
gene id: 8078:coro1a
uniprot id: A0A3Q2QBC4
names: Similarity
messages: Belongs to the WD repeat coronin family.

8078:nos1
gene id: 8078:nos1
uniprot id: Q6QN93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
messages: dendritic spine
messages: sarcolemma

8078:entpd5a
gene id: 8078:entpd5a
uniprot id: A0A147B4Z6
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8078:spsb1
gene id: 8078:spsb1
uniprot id: A0A3Q2QAL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

8078:LOC105927358
gene id: 8078:LOC105927358
uniprot id: A0A3Q2PUC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Membrane

8078:LOC105933890
gene id: 8078:LOC105933890
uniprot id: A0A3Q2SXQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

8078:hoxb1b
gene id: 8078:hoxb1b
uniprot id: A0A146ZQV9
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105929179
gene id: 8078:LOC105929179
uniprot id: A0A3Q2PJR2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:gnrh3
gene id: 8078:gnrh3
uniprot id: A9CSE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins.

8078:LOC105938943
gene id: 8078:LOC105938943
uniprot id: A0A3Q2PGW8
names: Subcellular Location Annotation
messages: extracellular space

8078:rpl23a
gene id: 8078:rpl23a
uniprot id: A0A3Q2PRQ4
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

8078:sypl1
gene id: 8078:sypl1
uniprot id: A0A147B277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8078:lxn
gene id: 8078:lxn
uniprot id: A0A3Q2NZQ6
uniprot id: A0A3Q2QBH5
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

8078:cep44
gene id: 8078:cep44
uniprot id: A0A3Q2QGA7
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

8078:arhgef3
gene id: 8078:arhgef3
uniprot id: A0A146V637
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

8078:sh3glb1a
gene id: 8078:sh3glb1a
uniprot id: A0A3Q2PXH1
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Mitochondrion outer membrane

8078:sh3gl3b
gene id: 8078:sh3gl3b
uniprot id: A0A147A503
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane

8078:sec22a
gene id: 8078:sec22a
uniprot id: A0A146P5X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

8078:zgc:162989
gene id: 8078:zgc:162989
uniprot id: A0A3Q2P510
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8078:serpinh1b
gene id: 8078:serpinh1b
uniprot id: A0A3Q2SNP2
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

8078:xrcc6
gene id: 8078:xrcc6
uniprot id: A0A3Q2UJZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus

8078:itpkcb
gene id: 8078:itpkcb
uniprot id: A0A3Q2P0Q4
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8078:tyk2
gene id: 8078:tyk2
uniprot id: A0A3Q2Q4W7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

8078:snrpa
gene id: 8078:snrpa
uniprot id: A0A3Q2QD32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM U1 A/B'' family.
messages: Nucleus

8078:fshb
gene id: 8078:fshb
uniprot id: P30971
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

8078:tmc8
gene id: 8078:tmc8
uniprot id: A0A3Q2PTZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

8078:adra2c
gene id: 8078:adra2c
uniprot id: A0A146SDJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:ca4a
gene id: 8078:ca4a
uniprot id: A0A3Q2T2J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cell membrane
messages: Interacts with SLC4A4.
messages: Membrane
messages: Reversible hydration of carbon dioxide.

8078:slc26a10
gene id: 8078:slc26a10
uniprot id: A0A3Q2NMH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

8078:tmem121ab
gene id: 8078:tmem121ab
uniprot id: A0A3Q2QRS1
names: Similarity
messages: Belongs to the TMEM121 family.

8078:ppp6c
gene id: 8078:ppp6c
uniprot id: A0A146Z634
names: Similarity
messages: Belongs to the PPP phosphatase family.

8078:eif2b2
gene id: 8078:eif2b2
uniprot id: A0A146P5E4
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

8078:LOC105933985
gene id: 8078:LOC105933985
uniprot id: A0A146ZWP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PARI family.
messages: Cytoplasm
messages: Nucleus

8078:chmp2ba
gene id: 8078:chmp2ba
uniprot id: A0A3Q2TF15
names: Similarity
messages: Belongs to the SNF7 family.

8078:cxcr4b
gene id: 8078:cxcr4b
uniprot id: A0A146UVB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8078:mrps10
gene id: 8078:mrps10
uniprot id: A0A3Q2Q5M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

8078:pclaf
gene id: 8078:pclaf
uniprot id: A0A3Q2PUB5
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

8078:LOC105931004
gene id: 8078:LOC105931004
uniprot id: A0A3Q2P2X4
names: Similarity
messages: Belongs to the RRM CPEB family.

8078:neurod1
gene id: 8078:neurod1
uniprot id: A0A146WVZ1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8078:marcksl1a
gene id: 8078:marcksl1a
uniprot id: A0A3Q2P1F2
names: Similarity
messages: Belongs to the MARCKS family.

8078:LOC105928192
gene id: 8078:LOC105928192
uniprot id: A0A3Q2PCD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

8078:tmem200a
gene id: 8078:tmem200a
uniprot id: A0A3Q2R286
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

8078:cc2d1b
gene id: 8078:cc2d1b
uniprot id: A0A3Q2NXU1
names: Similarity
messages: Belongs to the CC2D1 family.

8078:mboat1
gene id: 8078:mboat1
uniprot id: A0A3Q2PP22
names: Subcellular Location Annotation
messages: Membrane

8078:cln8
gene id: 8078:cln8
uniprot id: A0A3Q2P6C2
names: Subcellular Location Annotation
messages: Membrane

8078:camk1da
gene id: 8078:camk1da
uniprot id: A0A146YM37
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:pgpep1
gene id: 8078:pgpep1
uniprot id: A0A146P774
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

8078:LOC105930632
gene id: 8078:LOC105930632
uniprot id: A0A3Q2QC09
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:nadka
gene id: 8078:nadka
uniprot id: A0A146P6D9
names: Similarity
messages: Belongs to the NAD kinase family.

8078:coq4
gene id: 8078:coq4
uniprot id: A0A146ZUH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

8078:si:dkey-202e22.2
gene id: 8078:si:dkey-202e22.2
uniprot id: A0A3Q2NZH0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:pdcd4a
gene id: 8078:pdcd4a
uniprot id: A0A3Q2R355
names: Similarity
messages: Belongs to the PDCD4 family.

8078:cldn23a
gene id: 8078:cldn23a
uniprot id: A0A3Q2PCW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8078:tet1
gene id: 8078:tet1
uniprot id: A0A3Q2Q7I6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

8078:pld3
gene id: 8078:pld3
uniprot id: A0A3Q2PX14
names: Similarity
messages: Belongs to the phospholipase D family.

8078:ccnt2a
gene id: 8078:ccnt2a
uniprot id: A0A146VL02
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

8078:ezra
gene id: 8078:ezra
uniprot id: A0A3Q2QIZ1
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8078:pik3c2a
gene id: 8078:pik3c2a
uniprot id: A0A146X6I5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8078:LOC105932166
gene id: 8078:LOC105932166
uniprot id: A0A3Q2P321
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

8078:nxph1
gene id: 8078:nxph1
uniprot id: A0A147AVS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8078:atg12
gene id: 8078:atg12
uniprot id: A0A3Q2TET2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Ubiquitin-like protein involved in autophagic vesicle formation.

8078:dram1
gene id: 8078:dram1
uniprot id: A0A3Q2NZC9
names: Subcellular Location Annotation
messages: Membrane

8078:hnrnpk
gene id: 8078:hnrnpk
uniprot id: A0A146Z6V6
names: Subcellular Location Annotation
messages: nucleoplasm

8078:LOC105921461
gene id: 8078:LOC105921461
uniprot id: A0A146S4T4
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8078:wnt1
gene id: 8078:wnt1
uniprot id: A0A147A667
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8078:tspan17
gene id: 8078:tspan17
uniprot id: A0A3Q2P453
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:pfkfb2b
gene id: 8078:pfkfb2b
uniprot id: A0A3Q2PF52
uniprot id: A0A3Q2PG12
uniprot id: A0A3Q2PG16
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8078:LOC105925471
gene id: 8078:LOC105925471
uniprot id: A0A3Q2QDD8
uniprot id: A0A3Q2QE92
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8078:sys1
gene id: 8078:sys1
uniprot id: A0A146NJP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

8078:shpk
gene id: 8078:shpk
uniprot id: A0A3Q2PD21
names: Similarity
messages: Belongs to the FGGY kinase family.

8078:LOC105935925
gene id: 8078:LOC105935925
uniprot id: A0A3Q2QWB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.
messages: extracellular space

8078:LOC105938012
gene id: 8078:LOC105938012
uniprot id: A0A3Q2P0S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

8078:kif19
gene id: 8078:kif19
uniprot id: A0A3Q2P6D9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8078:sox1a
gene id: 8078:sox1a
uniprot id: A0A146RG25
names: Subcellular Location Annotation
messages: Nucleus

8078:phf5a
gene id: 8078:phf5a
uniprot id: A0A3Q2PEL5
names: Similarity
messages: Belongs to the PHF5 family.

8078:vdac3
gene id: 8078:vdac3
uniprot id: A0A3Q2SZI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
messages: Interacts with ARMC12 in a TBC1D21-dependent manner.
messages: Mitochondrion outer membrane

8078:ntn4
gene id: 8078:ntn4
uniprot id: A0A3Q2NTA0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:nfe2l1b
gene id: 8078:nfe2l1b
uniprot id: A0A3Q2NZ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. CNC subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8078:hprt1
gene id: 8078:hprt1
uniprot id: A0A3Q2PNA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

8078:LOC105938368
gene id: 8078:LOC105938368
uniprot id: A0A3Q2TCV4
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8078:LOC105928803
gene id: 8078:LOC105928803
uniprot id: A0A3Q2Q708
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

8078:pigl
gene id: 8078:pigl
uniprot id: A0A3Q2P2L4
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

8078:pym1
gene id: 8078:pym1
uniprot id: A0A3Q2NZD6
uniprot id: A0A3Q2NZL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pym family.
messages: Cytoplasm
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

8078:snrpg
gene id: 8078:snrpg
uniprot id: A0A3Q2PD77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

8078:LOC105934131
gene id: 8078:LOC105934131
uniprot id: A0A3Q2NNU7
names: Subcellular Location Annotation
messages: Nucleus

8078:inpp5b
gene id: 8078:inpp5b
uniprot id: A0A3Q2Q4J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

8078:LOC105930248
gene id: 8078:LOC105930248
uniprot id: A0A146MYF7
names: Similarity
messages: Belongs to the peptidase C14A family.

8078:LOC105922506
gene id: 8078:LOC105922506
uniprot id: A0A146P9L1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8078:hs3st2
gene id: 8078:hs3st2
uniprot id: A0A3Q2QYE8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8078:dhx15
gene id: 8078:dhx15
uniprot id: A0A3Q2Q288
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

8078:elp2
gene id: 8078:elp2
uniprot id: A0A3Q2NMG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

8078:mef2aa
gene id: 8078:mef2aa
uniprot id: A0A3Q2QBG5
names: Subcellular Location Annotation
messages: Nucleus

8078:zc3hc1
gene id: 8078:zc3hc1
uniprot id: A0A146P6D0
names: Subcellular Location Annotation
messages: Nucleus

8078:cpn1
gene id: 8078:cpn1
uniprot id: A0A3Q2P7U9
names: Similarity
messages: Belongs to the peptidase M14 family.

8078:ucp1
gene id: 8078:ucp1
uniprot id: A0A3Q2QEV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:thbs2a
gene id: 8078:thbs2a
uniprot id: A0A3Q2P1R9
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:numbl
gene id: 8078:numbl
uniprot id: A0A3Q2QU14
uniprot id: A0A3Q2QUH9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a role in the process of neurogenesis.

8078:LOC105937801
gene id: 8078:LOC105937801
uniprot id: A0A3Q2PMK5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8078:ntmt1
gene id: 8078:ntmt1
uniprot id: A0A3Q2NW60
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

8078:trnt1
gene id: 8078:trnt1
uniprot id: A0A3Q2PWG7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

8078:atad1b
gene id: 8078:atad1b
uniprot id: A0A147B0P5
names: Similarity
messages: Belongs to the AAA ATPase family.

8078:LOC105938273
gene id: 8078:LOC105938273
uniprot id: Q27R93
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

8078:lin54
gene id: 8078:lin54
uniprot id: A0A147A1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

8078:isca2
gene id: 8078:isca2
uniprot id: A0A147B554
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

8078:mffa
gene id: 8078:mffa
uniprot id: A0A3Q2NQS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

8078:cwc15
gene id: 8078:cwc15
uniprot id: A0A3Q2Q6Y0
names: Similarity
messages: Belongs to the CWC15 family.

8078:LOC105932531
gene id: 8078:LOC105932531
uniprot id: A0A146U606
names: Subcellular Location Annotation
messages: Membrane

8078:hhat
gene id: 8078:hhat
uniprot id: A0A3Q2QCN5
names: Subcellular Location Annotation
messages: Membrane

8078:ext1b
gene id: 8078:ext1b
uniprot id: A0A146SHU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8078:tbxas1
gene id: 8078:tbxas1
uniprot id: A0A3Q2QAZ5
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:atp6v1f
gene id: 8078:atp6v1f
uniprot id: A0A3Q2R4Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8078:arv1
gene id: 8078:arv1
uniprot id: A0A3Q2QQN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

8078:hopx
gene id: 8078:hopx
uniprot id: A0A3Q2PRH2
names: Subcellular Location Annotation
messages: Nucleus

8078:mmd2a
gene id: 8078:mmd2a
uniprot id: A0A3Q2UAJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8078:rbm47
gene id: 8078:rbm47
uniprot id: A0A3Q2P3X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Nucleus

8078:pmchl
gene id: 8078:pmchl
uniprot id: A0A147A8J1
names: Function
messages: Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.

8078:gngt2b
gene id: 8078:gngt2b
uniprot id: A0A3Q2PXU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8078:slc35a2
gene id: 8078:slc35a2
uniprot id: A0A3Q2PQ12
uniprot id: A0A3Q2UJR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

8078:LOC105921146
gene id: 8078:LOC105921146
uniprot id: A0A3Q2QPE6
names: Subcellular Location Annotation
messages: Membrane

8078:grna
gene id: 8078:grna
uniprot id: A0A3Q2U4M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8078:metap1
gene id: 8078:metap1
uniprot id: A0A3Q2U1B2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

8078:roraa
gene id: 8078:roraa
uniprot id: A0A3Q2NQN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:nfx1
gene id: 8078:nfx1
uniprot id: A0A3Q2UKF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

8078:LOC105936250
gene id: 8078:LOC105936250
uniprot id: A0A3Q2P926
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

8078:serpinf2a
gene id: 8078:serpinf2a
uniprot id: A0A146P9K0
names: Similarity
messages: Belongs to the serpin family.

8078:malsu1
gene id: 8078:malsu1
uniprot id: A0A3Q2PMH6
names: Similarity
messages: Belongs to the Iojap/RsfS family.

8078:brpf3b
gene id: 8078:brpf3b
uniprot id: A0A3Q2UD57
names: Subcellular Location Annotation
messages: Nucleus

8078:foxo3b
gene id: 8078:foxo3b
uniprot id: A0A146WIX4
names: Subcellular Location Annotation
messages: Nucleus

8078:si:ch211-117c9.5
gene id: 8078:si:ch211-117c9.5
uniprot id: A0A3Q2QXF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8078:gba
gene id: 8078:gba
uniprot id: A0A3Q2Q153
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

8078:calub
gene id: 8078:calub
uniprot id: A0A3Q2SQP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus
messages: Melanosome
messages: Membrane
messages: Sarcoplasmic reticulum lumen
messages: Secreted

8078:LOC105928844
gene id: 8078:LOC105928844
uniprot id: A0A3Q2NN74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8078:tlcd4b
gene id: 8078:tlcd4b
uniprot id: A0A3Q2P851
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105916871
gene id: 8078:LOC105916871
uniprot id: A0A3Q2QVP5
names: Subcellular Location Annotation
messages: Nucleus

8078:asl
gene id: 8078:asl
uniprot id: A0A3Q2TRL9
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

8078:runx1
gene id: 8078:runx1
uniprot id: A0A3Q2P5I9
names: Subcellular Location Annotation
messages: Nucleus

8078:actl6a
gene id: 8078:actl6a
uniprot id: A0A146QKQ0
names: Similarity
messages: Belongs to the actin family.

8078:LOC105927705
gene id: 8078:LOC105927705
uniprot id: A0A3Q2SV26
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:hcrtr2
gene id: 8078:hcrtr2
uniprot id: A0A147B183
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:nr2f6a
gene id: 8078:nr2f6a
uniprot id: A0A3Q2NZ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:rps10
gene id: 8078:rps10
uniprot id: A0A3Q2QT27
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

8078:ppme1
gene id: 8078:ppme1
uniprot id: A0A3Q2Q533
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

8078:LOC105926283
gene id: 8078:LOC105926283
uniprot id: A0A147AB25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TYROBP family.
messages: Cell membrane
messages: Membrane

8078:fxr2
gene id: 8078:fxr2
uniprot id: A0A3Q2Q4T1
names: Similarity
messages: Belongs to the FMR1 family.

8078:rab21
gene id: 8078:rab21
uniprot id: A0A146Z1E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Cytoplasmic vesicle membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: neuron projection
messages: trans-Golgi network

8078:ddx31
gene id: 8078:ddx31
uniprot id: A0A3Q2QHD6
names: Similarity
messages: Belongs to the DEAD box helicase family.

8078:gab1
gene id: 8078:gab1
uniprot id: A0A3Q2QDG6
uniprot id: A0A3Q2SZI9
names: Similarity
messages: Belongs to the GAB family.

8078:smc5
gene id: 8078:smc5
uniprot id: A0A3Q2U1Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Nucleus

8078:kpna6
gene id: 8078:kpna6
uniprot id: A0A3Q2QUB6
names: Similarity
messages: Belongs to the importin alpha family.

8078:scarb1
gene id: 8078:scarb1
uniprot id: A0A146YJX1
names: Similarity
messages: Belongs to the CD36 family.

8078:LOC105932231
gene id: 8078:LOC105932231
uniprot id: A0A3Q2QC33
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

8078:ddx11
gene id: 8078:ddx11
uniprot id: A0A3Q2NUU3
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

8078:LOC105916997
gene id: 8078:LOC105916997
uniprot id: A0A3Q2QNF9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:itih5
gene id: 8078:itih5
uniprot id: A0A3Q2P7X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

8078:LOC105931074
gene id: 8078:LOC105931074
uniprot id: A0A3Q2NZF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

8078:zeb2a
gene id: 8078:zeb2a
uniprot id: A0A3Q2NSU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
messages: Nucleus

8078:tns2a
gene id: 8078:tns2a
uniprot id: A0A3Q2PJ47
uniprot id: A0A3Q2QSB9
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8078:ubl3a
gene id: 8078:ubl3a
uniprot id: A0A146VAU3
names: Subcellular Location Annotation
messages: Membrane

8078:dnaaf1
gene id: 8078:dnaaf1
uniprot id: A0A3Q2NQU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF1 family.
messages: cilium

8078:nhp2
gene id: 8078:nhp2
uniprot id: A0A146NSP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

8078:LOC105939103
gene id: 8078:LOC105939103
uniprot id: A0A146ZKB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

8078:eml3
gene id: 8078:eml3
uniprot id: A0A3Q2TVD2
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

8078:slc51a
gene id: 8078:slc51a
uniprot id: A0A3Q2QAT4
names: Subcellular Location Annotation
messages: Membrane

8078:nectin1b
gene id: 8078:nectin1b
uniprot id: A0A3Q2TRG7
names: Subcellular Location Annotation
messages: Membrane

8078:senp8
gene id: 8078:senp8
uniprot id: A0A3Q2QRH1
names: Similarity
messages: Belongs to the peptidase C48 family.

8078:LOC105927311
gene id: 8078:LOC105927311
uniprot id: A0A147A9M0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:fbxo46
gene id: 8078:fbxo46
uniprot id: A0A3Q2THK3
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

8078:crsp7
gene id: 8078:crsp7
uniprot id: A0A146ZVT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 26 family.
messages: Nucleus

8078:sap130a
gene id: 8078:sap130a
uniprot id: A0A3Q2P7K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

8078:sec23b
gene id: 8078:sec23b
uniprot id: A0A146NQ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8078:LOC105919409
gene id: 8078:LOC105919409
uniprot id: A0A3Q2UC08
names: Similarity
messages: Belongs to the stathmin family.

8078:hhatlb
gene id: 8078:hhatlb
uniprot id: A0A146V5W3
uniprot id: A0A3Q2UEM3
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105927067
gene id: 8078:LOC105927067
uniprot id: A0A3Q2QG68
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

8078:hpse
gene id: 8078:hpse
uniprot id: A0A3Q2QEM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

8078:rsad1
gene id: 8078:rsad1
uniprot id: A0A146RIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Mitochondrion

8078:LOC105915995
gene id: 8078:LOC105915995
uniprot id: A0A3Q2PFI5
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8078:atp2b1a
gene id: 8078:atp2b1a
uniprot id: A0A3Q2PZY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:itga5
gene id: 8078:itga5
uniprot id: A0A3Q2QE34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8078:hoxc8a
gene id: 8078:hoxc8a
uniprot id: A0A147A5M3
names: Subcellular Location Annotation
messages: Nucleus

8078:prokr1a
gene id: 8078:prokr1a
uniprot id: A0A3Q2PJ83
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:chmp1a
gene id: 8078:chmp1a
uniprot id: A0A3Q2QFM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF7 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

8078:zgc:113531
gene id: 8078:zgc:113531
uniprot id: A0A147B1I7
names: Subcellular Location Annotation
messages: Synapse

8078:tecpr1a
gene id: 8078:tecpr1a
uniprot id: A0A3Q2TMW8
names: Similarity
messages: Belongs to the TECPR1 family.

8078:atad1a
gene id: 8078:atad1a
uniprot id: A0A3Q2U876
names: Similarity
messages: Belongs to the AAA ATPase family.

8078:ipo8
gene id: 8078:ipo8
uniprot id: A0A3Q2NW20
names: Subcellular Location Annotation
messages: Cytoplasm

8078:slc5a8l
gene id: 8078:slc5a8l
uniprot id: A0A147A7D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8078:LOC105927647
gene id: 8078:LOC105927647
uniprot id: A0A3Q2P3N1
names: Similarity
messages: Belongs to the peptidase S1C family.

8078:LOC105930239
gene id: 8078:LOC105930239
uniprot id: A0A3Q2PVZ9
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8078:galr1a
gene id: 8078:galr1a
uniprot id: A0A3Q2QSJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8078:lancl1
gene id: 8078:lancl1
uniprot id: A0A146P6X6
names: Similarity
messages: Belongs to the LanC-like protein family.

8078:vldlr
gene id: 8078:vldlr
uniprot id: A0A146VFP2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: clathrin-coated pit

8078:ier2a
gene id: 8078:ier2a
uniprot id: A0A3Q2PJY6
names: Similarity
messages: Belongs to the IER family.

8078:soul5
gene id: 8078:soul5
uniprot id: A0A3Q2TX60
names: Similarity
messages: Belongs to the HEBP family.

8078:lyrm9
gene id: 8078:lyrm9
uniprot id: A0A3Q2NNC4
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

8078:apoeb
gene id: 8078:apoeb
uniprot id: A0A3Q2PE76
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8078:prkcdb
gene id: 8078:prkcdb
uniprot id: A0A3Q2QA33
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

8078:elf2b
gene id: 8078:elf2b
uniprot id: A0A3Q2PGM5
uniprot id: A0A3Q2TAK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:mrpl42
gene id: 8078:mrpl42
uniprot id: A0A3Q2QWC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

8078:sec63
gene id: 8078:sec63
uniprot id: A0A3Q2P593
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105938805
gene id: 8078:LOC105938805
uniprot id: A0A3Q2QY20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:emx3
gene id: 8078:emx3
uniprot id: A0A3Q2PBC0
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105915241
gene id: 8078:LOC105915241
uniprot id: A0A146YVD4
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

8078:dnaja2b
gene id: 8078:dnaja2b
uniprot id: A0A3Q2Q9A9
names: Subcellular Location Annotation
messages: Membrane

8078:ehd2b
gene id: 8078:ehd2b
uniprot id: A0A3Q2TPX4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8078:LOC105931190
gene id: 8078:LOC105931190
uniprot id: A0A3Q2Q981
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8078:LOC105930103
gene id: 8078:LOC105930103
uniprot id: A0A3Q2NX80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

8078:grhprb
gene id: 8078:grhprb
uniprot id: A0A3Q2QH66
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

8078:bora
gene id: 8078:bora
uniprot id: A0A3Q2Q114
names: Similarity
messages: Belongs to the BORA family.

8078:ppp1r12a
gene id: 8078:ppp1r12a
uniprot id: A0A3Q2Q138
uniprot id: A0A3Q2R079
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

8078:tmem161b
gene id: 8078:tmem161b
uniprot id: A0A3Q2P426
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

8078:zfhx3
gene id: 8078:zfhx3
uniprot id: A0A146ZIK0
names: Subcellular Location Annotation
messages: Nucleus

8078:opn7d
gene id: 8078:opn7d
uniprot id: A0A3Q2R4I5
names: Subcellular Location Annotation
messages: Membrane

8078:pax3a
gene id: 8078:pax3a
uniprot id: A0A3Q2PTR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8078:mrps17
gene id: 8078:mrps17
uniprot id: A0A3Q2UQZ9
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

8078:mafa
gene id: 8078:mafa
uniprot id: A0A3Q2Q007
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

8078:LOC105930278
gene id: 8078:LOC105930278
uniprot id: A0A3Q2TNU6
names: Subcellular Location Annotation
messages: Nucleus

8078:ormdl2
gene id: 8078:ormdl2
uniprot id: A0A3Q2U3Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

8078:cers1
gene id: 8078:cers1
uniprot id: A0A146ZPS0
names: Subcellular Location Annotation
messages: Membrane

8078:polr1e
gene id: 8078:polr1e
uniprot id: A0A3Q2P825
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

8078:zdhhc20b
gene id: 8078:zdhhc20b
uniprot id: A0A3Q2NWN4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8078:slc2a3b
gene id: 8078:slc2a3b
uniprot id: A0A3Q2PMV7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8078:acsl2
gene id: 8078:acsl2
uniprot id: A0A147A9N6
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8078:LOC105919892
gene id: 8078:LOC105919892
uniprot id: A0A3Q2PKP4
names: Subcellular Location Annotation
messages: Membrane

8078:dusp27
gene id: 8078:dusp27
uniprot id: A0A3Q2QN86
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8078:ext1c
gene id: 8078:ext1c
uniprot id: A0A147AVU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8078:LOC105936683
gene id: 8078:LOC105936683
uniprot id: A0A146P7G1
names: Similarity
messages: Belongs to the UTP6 family.

8078:cstf3
gene id: 8078:cstf3
uniprot id: A0A3Q2PZ51
names: Subcellular Location Annotation
messages: Nucleus

8078:prdx1
gene id: 8078:prdx1
uniprot id: A0A146NSX5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

8078:rtn4a
gene id: 8078:rtn4a
uniprot id: A0A3Q2SNN4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:slc35a3a
gene id: 8078:slc35a3a
uniprot id: A0A3Q2SPR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

8078:uba1
gene id: 8078:uba1
uniprot id: A0A3Q2R0U1
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

8078:sft2d1
gene id: 8078:sft2d1
uniprot id: A0A146NRQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

8078:usp11
gene id: 8078:usp11
uniprot id: A0A3Q2QPG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

8078:xpo7
gene id: 8078:xpo7
uniprot id: A0A146WCJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

8078:hacd2
gene id: 8078:hacd2
uniprot id: A0A3Q2QS29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105936803
gene id: 8078:LOC105936803
uniprot id: A0A3Q2P3F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel MCLC family.
messages: Membrane
messages: Nucleus membrane

8078:nsun5
gene id: 8078:nsun5
uniprot id: A0A3Q2Q339
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

8078:meis2a
gene id: 8078:meis2a
uniprot id: A0A147AC55
uniprot id: A0A3Q2PWR5
uniprot id: A0A3Q2PYJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8078:kcnh1a
gene id: 8078:kcnh1a
uniprot id: A0A3Q2SYG5
names: Subcellular Location Annotation
messages: Membrane

8078:smarcb1a
gene id: 8078:smarcb1a
uniprot id: A0A146NTZ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

8078:nrg1
gene id: 8078:nrg1
uniprot id: A0A3Q2NQN8
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105926138
gene id: 8078:LOC105926138
uniprot id: A0A3Q2PYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8078:soul4
gene id: 8078:soul4
uniprot id: A0A3Q2PMX3
names: Similarity
messages: Belongs to the HEBP family.

8078:LOC105918966
gene id: 8078:LOC105918966
uniprot id: A0A147ASH6
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8078:LOC105935686
gene id: 8078:LOC105935686
uniprot id: A0A3Q2NX38
names: Subcellular Location Annotation
messages: Membrane

8078:ppil3
gene id: 8078:ppil3
uniprot id: A0A3Q2Q055
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8078:LOC105916403
gene id: 8078:LOC105916403
uniprot id: A0A147AXX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8078:snu13b
gene id: 8078:snu13b
uniprot id: A0A3Q2SY79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

8078:stoml1
gene id: 8078:stoml1
uniprot id: A0A3Q2NWU0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8078:ngfa
gene id: 8078:ngfa
uniprot id: A0A3Q2R1G5
names: Similarity
messages: Belongs to the NGF-beta family.

8078:timm21
gene id: 8078:timm21
uniprot id: A0A3Q2TL83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

8078:cops4
gene id: 8078:cops4
uniprot id: A0A3Q2P0N9
uniprot id: A0A3Q2QCT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

8078:myot
gene id: 8078:myot
uniprot id: A0A147B340
names: Subcellular Location Annotation
messages: Membrane

8078:paqr7a
gene id: 8078:paqr7a
uniprot id: A0A146ZWP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8078:LOC105918759
gene id: 8078:LOC105918759
uniprot id: A0A3Q2PFI6
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

8078:LOC105922004
gene id: 8078:LOC105922004
uniprot id: A0A147B5B6
names: Subcellular Location Annotation
messages: cytoskeleton

8078:lmbr1
gene id: 8078:lmbr1
uniprot id: A0A3Q2QS35
names: Similarity
messages: Belongs to the LIMR family.

8078:LOC105940079
gene id: 8078:LOC105940079
uniprot id: A0A3Q2QHU9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:LOC105925281
gene id: 8078:LOC105925281
uniprot id: A0A147ACQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

8078:nfrkb
gene id: 8078:nfrkb
uniprot id: A0A3Q2PN95
names: Subcellular Location Annotation
messages: Nucleus

8078:grm6b
gene id: 8078:grm6b
uniprot id: A0A3Q2QYK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8078:kdm2aa
gene id: 8078:kdm2aa
uniprot id: A0A146YFF4
uniprot id: A0A3Q2STC4
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8078:rap1gds1
gene id: 8078:rap1gds1
uniprot id: A0A3Q2NSH0
uniprot id: A0A3Q2NSK1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: cytosol

8078:adsl
gene id: 8078:adsl
uniprot id: A0A3Q2NZ51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

8078:atp6v0a1a
gene id: 8078:atp6v0a1a
uniprot id: A0A3Q2PCH9
uniprot id: A0A3Q2PCK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8078:pop7
gene id: 8078:pop7
uniprot id: A0A3Q2QNV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like Alba family.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
messages: nucleolus

8078:fgf12a
gene id: 8078:fgf12a
uniprot id: A0A3Q2PUR2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8078:sec23a
gene id: 8078:sec23a
uniprot id: A0A3Q2NVQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8078:tubd1
gene id: 8078:tubd1
uniprot id: A0A3Q2Q4K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Nucleus
messages: centriole
messages: cilium

8078:LOC105934800
gene id: 8078:LOC105934800
uniprot id: A0A146NLQ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:tmem147
gene id: 8078:tmem147
uniprot id: A0A3Q2PPB0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:aplp2
gene id: 8078:aplp2
uniprot id: A0A3Q2R203
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105918834
gene id: 8078:LOC105918834
uniprot id: A0A146SFP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8078:tp53
gene id: 8078:tp53
uniprot id: A0A146P3Z1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Nucleus

8078:eif3i
gene id: 8078:eif3i
uniprot id: A0A3Q2QVZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8078:pcmtd1
gene id: 8078:pcmtd1
uniprot id: A0A3Q2UDQ4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

8078:LOC105924042
gene id: 8078:LOC105924042
uniprot id: A0A147B3T7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8078:atp5pb
gene id: 8078:atp5pb
uniprot id: A0A3Q2NYH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

8078:mtfr1
gene id: 8078:mtfr1
uniprot id: A0A146YX06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

8078:tmem267
gene id: 8078:tmem267
uniprot id: A0A146WMN2
names: Subcellular Location Annotation
messages: Membrane

8078:hmbox1b
gene id: 8078:hmbox1b
uniprot id: A0A3Q2U5A6
names: Subcellular Location Annotation
messages: Nucleus

8078:KEG95 p03
gene id: 8078:KEG95_p03
uniprot id: B7U7W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

8078:tmprss4a
gene id: 8078:tmprss4a
uniprot id: A0A3Q2QCX2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8078:LOC105917980
gene id: 8078:LOC105917980
uniprot id: A0A3Q2Q1V1
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

8078:si:dkey-33c12.3
gene id: 8078:si:dkey-33c12.3
uniprot id: A0A3Q2SW96
names: Similarity
messages: Belongs to the intermediate filament family.

8078:phactr4b
gene id: 8078:phactr4b
uniprot id: A0A3Q2PPD8
uniprot id: A0A3Q2QT76
uniprot id: A0A3Q2QTW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

8078:nab1b
gene id: 8078:nab1b
uniprot id: A0A3Q2QXK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

8078:naa40
gene id: 8078:naa40
uniprot id: A0A146Z5U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

8078:ednraa
gene id: 8078:ednraa
uniprot id: B1PCG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

8078:LOC105934622
gene id: 8078:LOC105934622
uniprot id: A0A3Q2SPW3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8078:ddi2
gene id: 8078:ddi2
uniprot id: A0A3Q2R0I8
names: Similarity
messages: Belongs to the DDI1 family.

8078:barx1
gene id: 8078:barx1
uniprot id: A0A3Q2NQD2
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105934139
gene id: 8078:LOC105934139
uniprot id: A0A3Q2TX53
uniprot id: A0A3Q2TX56
names: Subcellular Location Annotation
messages: Membrane

8078:susd6
gene id: 8078:susd6
uniprot id: A0A3Q2QI60
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105933834
gene id: 8078:LOC105933834
uniprot id: A0A146XFA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: Endomembrane system
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: clathrin-coated pit
messages: cytosol
messages: synaptic vesicle membrane

8078:cmtm8b
gene id: 8078:cmtm8b
uniprot id: A0A3Q2QT04
names: Subcellular Location Annotation
messages: Membrane

8078:zcchc4
gene id: 8078:zcchc4
uniprot id: A0A147AC64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC4 family.
messages: Cytoplasm
messages: nucleolus

8078:LOC105915994
gene id: 8078:LOC105915994
uniprot id: A0A3Q2PEQ2
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8078:elp3
gene id: 8078:elp3
uniprot id: A0A146NUC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

8078:LOC105927062
gene id: 8078:LOC105927062
uniprot id: A0A3Q2U9N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

8078:LOC105935531
gene id: 8078:LOC105935531
uniprot id: A0A3Q2P932
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:glyr1
gene id: 8078:glyr1
uniprot id: A0A146P4L0
uniprot id: A0A146ZMI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Chromosome

8078:LOC105932749
gene id: 8078:LOC105932749
uniprot id: A0A3Q2TAG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8078:lpcat4
gene id: 8078:lpcat4
uniprot id: A0A3Q2QZI2
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8078:kcnj2a
gene id: 8078:kcnj2a
uniprot id: A0A3Q2T5R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Membrane

8078:tubgcp3
gene id: 8078:tubgcp3
uniprot id: A0A3Q2Q1C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

8078:rps3a
gene id: 8078:rps3a
uniprot id: A0A3Q2P581
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).
messages: Cytoplasm

8078:mrps9
gene id: 8078:mrps9
uniprot id: A0A3Q2U843
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

8078:LOC105930290
gene id: 8078:LOC105930290
uniprot id: A0A3Q2TJ92
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

8078:LOC105921149
gene id: 8078:LOC105921149
uniprot id: A0A3Q2QNL9
names: Subcellular Location Annotation
messages: Membrane

8078:ppa1b
gene id: 8078:ppa1b
uniprot id: A0A146ZKZ1
names: Similarity
messages: Belongs to the PPase family.

8078:acads
gene id: 8078:acads
uniprot id: A0A3Q2ST36
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8078:LOC105917712
gene id: 8078:LOC105917712
uniprot id: A0A3Q2QHY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

8078:sh3rf1
gene id: 8078:sh3rf1
uniprot id: A0A146X9B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3RF family.
messages: lamellipodium
messages: perinuclear region
messages: trans-Golgi network

8078:LOC105921517
gene id: 8078:LOC105921517
uniprot id: A0A3Q2QYA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8078:LOC105919136
gene id: 8078:LOC105919136
uniprot id: A0A3Q2R0R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

8078:LOC105938137
gene id: 8078:LOC105938137
uniprot id: A0A3Q2STE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

8078:cx39.4
gene id: 8078:cx39.4
uniprot id: A0A146NVF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8078:LOC105939721
gene id: 8078:LOC105939721
uniprot id: A0A3Q2QAQ6
names: Function
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

8078:tm4sf5
gene id: 8078:tm4sf5
uniprot id: A0A3Q2QVY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8078:trarg1a
gene id: 8078:trarg1a
uniprot id: A0A146ZQI1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8078:gem
gene id: 8078:gem
uniprot id: A0A3Q2PIG9
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

8078:LOC105916146
gene id: 8078:LOC105916146
uniprot id: A0A3Q2P3N6
names: Subcellular Location Annotation
messages: Nucleus

8078:gpr18
gene id: 8078:gpr18
uniprot id: A0A3Q2QK74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

8078:map1lc3a
gene id: 8078:map1lc3a
uniprot id: A0A3Q2PQW7
names: Similarity
messages: Belongs to the ATG8 family.

8078:clul1
gene id: 8078:clul1
uniprot id: A0A3Q2PTD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

8078:zgc:85843
gene id: 8078:zgc:85843
uniprot id: A0A3Q2NS02
names: Subcellular Location Annotation
messages: Membrane

8078:cdk14
gene id: 8078:cdk14
uniprot id: A0A3Q2P3R8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:si:dkey-165a24.9
gene id: 8078:si:dkey-165a24.9
uniprot id: A0A146NTH8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:bnip1a
gene id: 8078:bnip1a
uniprot id: A0A3Q2QFT6
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105927453
gene id: 8078:LOC105927453
uniprot id: A0A3Q2TD29
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

8078:tmem205
gene id: 8078:tmem205
uniprot id: A0A3Q2P7Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

8078:hacd3
gene id: 8078:hacd3
uniprot id: A0A3Q2Q9U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:LOC105916365
gene id: 8078:LOC105916365
uniprot id: A0A3Q2PS37
uniprot id: A0A3Q2QUB4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8078:top2b
gene id: 8078:top2b
uniprot id: A0A3Q2PTU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

8078:zgc:110366
gene id: 8078:zgc:110366
uniprot id: A0A3Q2QVZ1
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8078:cdkn1d
gene id: 8078:cdkn1d
uniprot id: A0A3Q2P7C7
names: Similarity
messages: Belongs to the CDI family.

8078:ddah1
gene id: 8078:ddah1
uniprot id: A0A3Q2Q4U0
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

8078:LOC105925882
gene id: 8078:LOC105925882
uniprot id: A0A3Q2UDM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

8078:LOC105930455
gene id: 8078:LOC105930455
uniprot id: A0A3Q2T969
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

8078:hoxd12a
gene id: 8078:hoxd12a
uniprot id: A0A3Q2P309
names: Subcellular Location Annotation
messages: Nucleus

8078:ralaa
gene id: 8078:ralaa
uniprot id: A0A3Q2Q6R2
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8078:LOC105916057
gene id: 8078:LOC105916057
uniprot id: A0A146RAL7
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

8078:sema3aa
gene id: 8078:sema3aa
uniprot id: A0A147B6E4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:crabp1a
gene id: 8078:crabp1a
uniprot id: A0A3Q2QUU3
names: Function
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.

8078:mettl4
gene id: 8078:mettl4
uniprot id: A0A3Q2QN71
names: Similarity
messages: Belongs to the MT-A70-like family.

8078:hoxd10a
gene id: 8078:hoxd10a
uniprot id: A0A3Q2QEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8078:LOC105927767
gene id: 8078:LOC105927767
uniprot id: A0A146WV33
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105935220
gene id: 8078:LOC105935220
uniprot id: A0A146VNC7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

8078:snrpe
gene id: 8078:snrpe
uniprot id: A0A3Q2TN38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

8078:mmp15b
gene id: 8078:mmp15b
uniprot id: A0A147ABV3
names: Similarity
messages: Belongs to the peptidase M10A family.

8078:fmc1
gene id: 8078:fmc1
uniprot id: A0A3Q2QD40
names: Similarity
messages: Belongs to the FMC1 family.

8078:tmem165
gene id: 8078:tmem165
uniprot id: A0A3Q2PHJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

8078:ppp1r2
gene id: 8078:ppp1r2
uniprot id: A0A146WRS0
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

8078:nme7
gene id: 8078:nme7
uniprot id: A0A146NSG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: cilium axoneme
messages: lamellipodium
messages: ruffle

8078:poll
gene id: 8078:poll
uniprot id: A0A3Q2R380
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus

8078:arl6ip4
gene id: 8078:arl6ip4
uniprot id: A0A3Q2PQC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL6IP4 family.
messages: Nucleus speckle
messages: nucleolus

8078:ern2
gene id: 8078:ern2
uniprot id: A0A3Q2Q8E2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:irf2bp1
gene id: 8078:irf2bp1
uniprot id: A0A3Q2R177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

8078:hpdl
gene id: 8078:hpdl
uniprot id: A0A3Q2PDX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

8078:anapc13
gene id: 8078:anapc13
uniprot id: A0A3Q2T2N0
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

8078:gfm1
gene id: 8078:gfm1
uniprot id: A0A3Q2NZP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion

8078:olfm1b
gene id: 8078:olfm1b
uniprot id: A0A146WNR1
uniprot id: A0A3Q2NQ19
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8078:morf4l1
gene id: 8078:morf4l1
uniprot id: A0A147B2Z9
names: Subcellular Location Annotation
messages: Nucleus

8078:tmem88a
gene id: 8078:tmem88a
uniprot id: A0A3Q2SVT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

8078:shha
gene id: 8078:shha
uniprot id: A0A147AUC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

8078:lin7b
gene id: 8078:lin7b
uniprot id: A0A147B3M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

8078:capza1b
gene id: 8078:capza1b
uniprot id: A0A3Q2QXU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

8078:nfyba
gene id: 8078:nfyba
uniprot id: A0A3Q2PM32
names: Function
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.

8078:hgd
gene id: 8078:hgd
uniprot id: A0A3Q2Q8W0
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

8078:LOC105937663
gene id: 8078:LOC105937663
uniprot id: A0A3Q2PXT4
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

8078:pax1a
gene id: 8078:pax1a
uniprot id: A0A147ABF7
names: Subcellular Location Annotation
messages: Nucleus

8078:fgf5
gene id: 8078:fgf5
uniprot id: A0A3Q2PGD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heparin-binding growth factors family.
messages: Interacts with FGFR1 and FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
messages: Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.
messages: Secreted

8078:hacd1
gene id: 8078:hacd1
uniprot id: A0A146YBY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105933138
gene id: 8078:LOC105933138
uniprot id: A0A3Q2PVP3
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105931849
gene id: 8078:LOC105931849
uniprot id: A0A3Q2R2Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

8078:igf2b
gene id: 8078:igf2b
uniprot id: A0A3Q2QK98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8078:spra
gene id: 8078:spra
uniprot id: A0A3Q2QER1
names: Similarity
messages: Belongs to the sepiapterin reductase family.

8078:ca7
gene id: 8078:ca7
uniprot id: A0A3Q2TJB5
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8078:yju2
gene id: 8078:yju2
uniprot id: A0A3Q2T3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

8078:LOC105935247
gene id: 8078:LOC105935247
uniprot id: A0A146VN27
names: Subcellular Location Annotation
messages: Membrane

8078:tmem115
gene id: 8078:tmem115
uniprot id: A0A3Q2PSX2
names: Subcellular Location Annotation
messages: Membrane

8078:yaf2
gene id: 8078:yaf2
uniprot id: A0A3Q2P2X3
names: Subcellular Location Annotation
messages: Nucleus

8078:foxp4
gene id: 8078:foxp4
uniprot id: A0A3Q2R0L9
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105915920
gene id: 8078:LOC105915920
uniprot id: A0A3Q2QR58
names: Similarity
messages: Belongs to the myozenin family.

8078:rab32a
gene id: 8078:rab32a
uniprot id: A0A3Q2Q4I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8078:barhl2
gene id: 8078:barhl2
uniprot id: A0A3Q2UB19
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105931717
gene id: 8078:LOC105931717
uniprot id: A0A3Q2P1R8
names: Similarity
messages: Belongs to the intermediate filament family.

8078:ghitm
gene id: 8078:ghitm
uniprot id: A0A3Q2QN07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8078:ucmaa
gene id: 8078:ucmaa
uniprot id: A0A147AWW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

8078:ndufb6
gene id: 8078:ndufb6
uniprot id: A0A3Q2Q1U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8078:LOC105935522
gene id: 8078:LOC105935522
uniprot id: A0A3Q2QIK4
names: Similarity
messages: Belongs to the SEC6 family.

8078:klc1a
gene id: 8078:klc1a
uniprot id: A0A3Q2QIQ8
uniprot id: A0A3Q2QJ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8078:cry5
gene id: 8078:cry5
uniprot id: A0A147A3E3
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

8078:LOC105920033
gene id: 8078:LOC105920033
uniprot id: A0A3Q2P8E3
names: Subcellular Location Annotation
messages: extracellular space

8078:mcrip2
gene id: 8078:mcrip2
uniprot id: A0A3Q2PFJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

8078:sparc
gene id: 8078:sparc
uniprot id: A0A3Q2PLF1
names: Similarity
messages: Belongs to the SPARC family.

8078:api5
gene id: 8078:api5
uniprot id: A0A147ABQ0
names: Similarity
messages: Belongs to the API5 family.

8078:srp19
gene id: 8078:srp19
uniprot id: A0A3Q2QX80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm

8078:LOC105918299
gene id: 8078:LOC105918299
uniprot id: A0A3Q2SZX0
names: Subcellular Location Annotation
messages: extracellular space

8078:adprm
gene id: 8078:adprm
uniprot id: A0A3Q2QZG3
names: Similarity
names: Subunit
messages: Belongs to the ADPRibase-Mn family.
messages: Monomer.

8078:rprd1b
gene id: 8078:rprd1b
uniprot id: A0A3Q2Q5T9
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

8078:khdrbs1a
gene id: 8078:khdrbs1a
uniprot id: A0A3Q2PQF6
names: Similarity
messages: Belongs to the KHDRBS family.

8078:LOC105925775
gene id: 8078:LOC105925775
uniprot id: A0A3Q2PNY8
uniprot id: A0A3Q2QSW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

8078:aldh6a1
gene id: 8078:aldh6a1
uniprot id: A0A147B663
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

8078:afmid
gene id: 8078:afmid
uniprot id: A0A147AZ47
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: Nucleus
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
messages: cytosol

8078:prpf31
gene id: 8078:prpf31
uniprot id: A0A146P6G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Cajal body

8078:ampd1
gene id: 8078:ampd1
uniprot id: A0A3Q2QK40
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

8078:LOC105930221
gene id: 8078:LOC105930221
uniprot id: A0A3Q2PYY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8078:pklr
gene id: 8078:pklr
uniprot id: A0A3Q2R1L8
uniprot id: A0A3Q2UQ79
names: Similarity
messages: Belongs to the pyruvate kinase family.

8078:LOC105938382
gene id: 8078:LOC105938382
uniprot id: A0A146ZMY6
names: Similarity
messages: Belongs to the actin family.

8078:kri1
gene id: 8078:kri1
uniprot id: A0A3Q2P944
names: Similarity
messages: Belongs to the KRI1 family.

8078:prpf19
gene id: 8078:prpf19
uniprot id: A0A146ZIR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

8078:map1lc3cl
gene id: 8078:map1lc3cl
uniprot id: A0A3Q2NS05
names: Similarity
messages: Belongs to the ATG8 family.

8078:si:dkey-190g6.2
gene id: 8078:si:dkey-190g6.2
uniprot id: A0A3Q2P016
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

8078:LOC105932715
gene id: 8078:LOC105932715
uniprot id: A0A3Q2QN20
names: Subcellular Location Annotation
messages: Nucleus

8078:slc46a3
gene id: 8078:slc46a3
uniprot id: A0A146Z6C9
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105937441
gene id: 8078:LOC105937441
uniprot id: A0A146ZNK3
names: Similarity
messages: Belongs to the ZC3H12 family.

8078:LOC105932136
gene id: 8078:LOC105932136
uniprot id: A0A3Q2P2M7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

8078:upp2
gene id: 8078:upp2
uniprot id: A0A3Q2Q2K3
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

8078:btf3l4
gene id: 8078:btf3l4
uniprot id: A0A3Q2R329
names: Similarity
messages: Belongs to the NAC-beta family.

8078:si:ch211-120k19.1
gene id: 8078:si:ch211-120k19.1
uniprot id: A0A3Q2TV86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

8078:LOC105924696
gene id: 8078:LOC105924696
uniprot id: A0A3Q2QK06
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:neu1
gene id: 8078:neu1
uniprot id: A0A146NNZ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8078:hmgn3
gene id: 8078:hmgn3
uniprot id: A0A3Q2QZU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

8078:LOC105938272
gene id: 8078:LOC105938272
uniprot id: A0A3Q2QXT4
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

8078:LOC105917855
gene id: 8078:LOC105917855
uniprot id: A0A3Q2NXW5
names: Similarity
messages: Belongs to the HMBS family.

8078:tbl1xr1b
gene id: 8078:tbl1xr1b
uniprot id: A0A3Q2QSX9
names: Similarity
messages: Belongs to the WD repeat EBI family.

8078:flot1b
gene id: 8078:flot1b
uniprot id: A0A3Q2QJ20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

8078:prdx6
gene id: 8078:prdx6
uniprot id: A0A3Q2NMU9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

8078:cdk6
gene id: 8078:cdk6
uniprot id: A0A3Q2PF56
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:pkp1b
gene id: 8078:pkp1b
uniprot id: A0A3Q2PQ68
names: Similarity
messages: Belongs to the beta-catenin family.

8078:myoc
gene id: 8078:myoc
uniprot id: A0A3Q2Q3Y5
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion intermembrane space
messages: Mitochondrion outer membrane
messages: Rough endoplasmic reticulum
messages: cilium
messages: extracellular exosome
messages: extracellular space

8078:ssh2a
gene id: 8078:ssh2a
uniprot id: A0A3Q2NN78
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

8078:adamts1
gene id: 8078:adamts1
uniprot id: A0A3Q2PX51
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8078:LOC105931226
gene id: 8078:LOC105931226
uniprot id: A0A3Q2NRV1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8078:drd4b
gene id: 8078:drd4b
uniprot id: A0A146ZM55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:LOC105919999
gene id: 8078:LOC105919999
uniprot id: A0A3Q2PD61
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

8078:LOC105926745
gene id: 8078:LOC105926745
uniprot id: A0A3Q2UNX9
names: Similarity
messages: Belongs to the potassium channel KCNE family.

8078:eipr1
gene id: 8078:eipr1
uniprot id: A0A3Q2P100
names: Similarity
messages: Belongs to the WD repeat EIPR1 family.

8078:hdac5
gene id: 8078:hdac5
uniprot id: A0A3Q2P7S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

8078:dmrta2
gene id: 8078:dmrta2
uniprot id: A0A3Q2NW91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

8078:LOC105917477
gene id: 8078:LOC105917477
uniprot id: A0A146YIC4
names: Subcellular Location Annotation
messages: Nucleus

8078:top3a
gene id: 8078:top3a
uniprot id: A0A3Q2R064
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

8078:sox19b
gene id: 8078:sox19b
uniprot id: A0A3Q2TCX5
names: Subcellular Location Annotation
messages: Nucleus

8078:ldhba
gene id: 8078:ldhba
uniprot id: A0A146WJR7
uniprot id: P20373
names: Function
names: Polymorphism
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.
messages: Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
messages: Isolates from various regions of the US and Canada show some variations. PubMed:8105474 has sequenced LDH-B isolates called Florida 1A, 1B, 2A and 2B; Georgia 2A and 2B; Maine 2A; New Jersey 121A, 121B, 137A, 137B and 197B; Nova Scotia 1A, 1B, 2A and 2B.

8078:ncam3
gene id: 8078:ncam3
uniprot id: A0A3Q2PPN3
names: Subcellular Location Annotation
messages: Membrane

8078:fmnl2a
gene id: 8078:fmnl2a
uniprot id: A0A3Q2P3G1
uniprot id: A0A3Q2P4C2
names: Similarity
messages: Belongs to the formin homology family.

8078:map2k4a
gene id: 8078:map2k4a
uniprot id: A0A3Q2QRL1
uniprot id: A0A3Q2TE07
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:cldn7a
gene id: 8078:cldn7a
uniprot id: A0A3Q2NS33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8078:obsl1a
gene id: 8078:obsl1a
uniprot id: A0A3Q2PPH7
names: Subcellular Location Annotation
messages: Membrane

8078:nr4a1
gene id: 8078:nr4a1
uniprot id: A0A3Q2NZR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:LOC105920967
gene id: 8078:LOC105920967
uniprot id: A0A3Q2U397
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

8078:noxred1
gene id: 8078:noxred1
uniprot id: A0A147B500
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

8078:ecrg4a
gene id: 8078:ecrg4a
uniprot id: A0A3Q2PFI9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

8078:LOC105917634
gene id: 8078:LOC105917634
uniprot id: A0A147AV97
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8078:fa2h
gene id: 8078:fa2h
uniprot id: A0A147A4E3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:rusf1
gene id: 8078:rusf1
uniprot id: A0A3Q2T6J6
names: Similarity
messages: Belongs to the RUS1 family.

8078:surf4
gene id: 8078:surf4
uniprot id: A0A3Q2NV21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

8078:trappc3
gene id: 8078:trappc3
uniprot id: A0A146P711
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

8078:sdhaf1
gene id: 8078:sdhaf1
uniprot id: A0A3Q2QFD2
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

8078:LOC105928603
gene id: 8078:LOC105928603
uniprot id: A0A7D3QBG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8078:LOC105935688
gene id: 8078:LOC105935688
uniprot id: A0A146VKM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

8078:LOC105932700
gene id: 8078:LOC105932700
uniprot id: A0A3Q2PKG6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8078:rbm48
gene id: 8078:rbm48
uniprot id: A0A3Q2QF72
names: Similarity
messages: Belongs to the RBM48 family.

8078:armc1
gene id: 8078:armc1
uniprot id: A0A3Q2NU46
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8078:LOC105921455
gene id: 8078:LOC105921455
uniprot id: A0A3Q2TZ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8078:mst1rb
gene id: 8078:mst1rb
uniprot id: A0A147B1N9
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:sptssb
gene id: 8078:sptssb
uniprot id: A0A3Q2PNN3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:hoxa9a
gene id: 8078:hoxa9a
uniprot id: A0A3Q2QQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8078:LOC105919001
gene id: 8078:LOC105919001
uniprot id: A0A3Q2SRJ9
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

8078:cct3
gene id: 8078:cct3
uniprot id: A0A3Q2PPY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8078:LOC105919031
gene id: 8078:LOC105919031
uniprot id: A0A3Q2Q6S8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:mis18a
gene id: 8078:mis18a
uniprot id: A0A146PA37
names: Function
names: Subcellular Location Annotation
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

8078:wasf1
gene id: 8078:wasf1
uniprot id: A0A147A4J2
uniprot id: A0A3Q2NN31
uniprot id: A0A3Q2NN32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8078:LOC118556000
gene id: 8078:LOC118556000
uniprot id: A0A3Q2PZL0
names: Similarity
messages: Belongs to the peptidase C1 family.

8078:ugt8
gene id: 8078:ugt8
uniprot id: A0A3Q2P3V3
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

8078:pcolce2b
gene id: 8078:pcolce2b
uniprot id: A0A147AUT3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:slc25a16
gene id: 8078:slc25a16
uniprot id: A0A3Q2NQS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:mnd1
gene id: 8078:mnd1
uniprot id: A0A146P497
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

8078:LOC105919032
gene id: 8078:LOC105919032
uniprot id: A0A3Q2Q845
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8078:eva1ba
gene id: 8078:eva1ba
uniprot id: A0A3Q2SNB9
names: Similarity
messages: Belongs to the EVA1 family.

8078:pfkla
gene id: 8078:pfkla
uniprot id: A0A3Q2U7R3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:aldh3b2
gene id: 8078:aldh3b2
uniprot id: A0A146WZI9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8078:rabac1
gene id: 8078:rabac1
uniprot id: A0A146W6R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8078:LOC105935034
gene id: 8078:LOC105935034
uniprot id: A0A146YYV6
names: Similarity
messages: Belongs to the TTC39 family.

8078:barx2
gene id: 8078:barx2
uniprot id: A0A3Q2NR59
names: Subcellular Location Annotation
messages: Nucleus

8078:epgn
gene id: 8078:epgn
uniprot id: A0A3Q2QAQ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:rad50
gene id: 8078:rad50
uniprot id: A0A3Q2P9U9
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

8078:ctsf
gene id: 8078:ctsf
uniprot id: A0A3Q2QT37
names: Similarity
messages: Belongs to the peptidase C1 family.

8078:map2k5
gene id: 8078:map2k5
uniprot id: A0A3Q2NT95
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:LOC105937466
gene id: 8078:LOC105937466
uniprot id: A0A3Q2P172
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

8078:gimap4
gene id: 8078:gimap4
uniprot id: A0A3Q2QPS9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8078:LOC105929417
gene id: 8078:LOC105929417
uniprot id: A0A3Q2Q6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:LOC105937411
gene id: 8078:LOC105937411
uniprot id: A0A3Q2Q4N5
names: Similarity
messages: Belongs to the sorting nexin family.

8078:ptgs2b
gene id: 8078:ptgs2b
uniprot id: Q6QNF2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Microsome membrane

8078:bdh1
gene id: 8078:bdh1
uniprot id: A0A3Q2QQT2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:LOC105920903
gene id: 8078:LOC105920903
uniprot id: A0A3Q2PYG0
names: Subcellular Location Annotation
messages: Membrane

8078:nat10
gene id: 8078:nat10
uniprot id: A0A146V5R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with THUMPD1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

8078:pik3r2
gene id: 8078:pik3r2
uniprot id: A0A3Q2NZT5
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

8078:man2b2
gene id: 8078:man2b2
uniprot id: A0A3Q2QTG9
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

8078:dusp2
gene id: 8078:dusp2
uniprot id: A0A3Q2Q026
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

8078:LOC105916248
gene id: 8078:LOC105916248
uniprot id: A0A3Q2PZU0
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:rbx1
gene id: 8078:rbx1
uniprot id: A0A3Q2QZ35
names: Similarity
messages: Belongs to the RING-box family.

8078:LOC105934263
gene id: 8078:LOC105934263
uniprot id: A0A146VTF9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:myo9aa
gene id: 8078:myo9aa
uniprot id: A0A146YNK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Cytoplasm
messages: Membrane
messages: Synapse
messages: growth cone

8078:chst2b
gene id: 8078:chst2b
uniprot id: A0A3Q2PQ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8078:mmp13b
gene id: 8078:mmp13b
uniprot id: A0A147ASB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Secreted

8078:LOC105917683
gene id: 8078:LOC105917683
uniprot id: A0A3Q2QID5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8078:cfl2
gene id: 8078:cfl2
uniprot id: A0A146ML52
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

8078:LOC105935109
gene id: 8078:LOC105935109
uniprot id: A0A146VNZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

8078:cdk11b
gene id: 8078:cdk11b
uniprot id: A0A3Q2PF08
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

8078:arpp19b
gene id: 8078:arpp19b
uniprot id: A0A3Q2PB42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

8078:LOC105916612
gene id: 8078:LOC105916612
uniprot id: A0A3Q2P4S5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8078:sdhb
gene id: 8078:sdhb
uniprot id: A0A3Q2NWP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

8078:grk6
gene id: 8078:grk6
uniprot id: A0A3Q2QSU1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8078:LOC105936496
gene id: 8078:LOC105936496
uniprot id: A0A146ZQC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

8078:adh5
gene id: 8078:adh5
uniprot id: A0A3Q2T0S8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

8078:rnf7
gene id: 8078:rnf7
uniprot id: A0A3Q2SQX2
names: Similarity
messages: Belongs to the RING-box family.

8078:si:dkey-264d12.4
gene id: 8078:si:dkey-264d12.4
uniprot id: A0A3Q2QVW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

8078:efhb
gene id: 8078:efhb
uniprot id: A0A3Q2P5C9
names: Subcellular Location Annotation
messages: cilium axoneme

8078:tspan33b
gene id: 8078:tspan33b
uniprot id: A0A146X470
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:nsmce2
gene id: 8078:nsmce2
uniprot id: A0A3Q2NVQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

8078:nrd1a
gene id: 8078:nrd1a
uniprot id: A0A146P5C6
names: Similarity
messages: Belongs to the peptidase M16 family.

8078:psma3
gene id: 8078:psma3
uniprot id: A0A3Q2NXC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8078:mcm7
gene id: 8078:mcm7
uniprot id: A0A3Q2PJV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

8078:hsd17b1
gene id: 8078:hsd17b1
uniprot id: A0A3Q2PCE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Favors the reduction of estrogens and androgens. Uses preferentially NADH.

8078:gpsm2
gene id: 8078:gpsm2
uniprot id: A0A3Q2NSH8
uniprot id: A0A3Q2Q7B8
names: Similarity
messages: Belongs to the GPSM family.

8078:hlx1
gene id: 8078:hlx1
uniprot id: A0A146P4I2
uniprot id: A0A3Q2UQV3
names: Subcellular Location Annotation
messages: Nucleus

8078:hoxa10b
gene id: 8078:hoxa10b
uniprot id: A0A3Q2PLH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8078:prox2
gene id: 8078:prox2
uniprot id: A0A147B670
names: Subcellular Location Annotation
messages: Nucleus

8078:slc6a1b
gene id: 8078:slc6a1b
uniprot id: A0A147A1J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8078:dlgap5
gene id: 8078:dlgap5
uniprot id: A0A3Q2UMG7
names: Similarity
messages: Belongs to the SAPAP family.

8078:wdr82
gene id: 8078:wdr82
uniprot id: A0A146NM43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

8078:tapt1b
gene id: 8078:tapt1b
uniprot id: A0A3Q2PA44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

8078:mfn1b
gene id: 8078:mfn1b
uniprot id: A0A3Q2SZU9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8078:hoxc13a
gene id: 8078:hoxc13a
uniprot id: A0A147A5K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8078:fam126a
gene id: 8078:fam126a
uniprot id: A0A146ZND1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8078:LOC105929498
gene id: 8078:LOC105929498
uniprot id: A0A3Q2NNR1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8078:ddx54
gene id: 8078:ddx54
uniprot id: A0A3Q2PSF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: nucleolus

8078:supt3h
gene id: 8078:supt3h
uniprot id: A0A3Q2T997
names: Subcellular Location Annotation
messages: Nucleus

8078:tctex1d2
gene id: 8078:tctex1d2
uniprot id: A0A3Q2T1C3
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8078:LOC105928969
gene id: 8078:LOC105928969
uniprot id: A0A146WP87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8078:pi4k2b
gene id: 8078:pi4k2b
uniprot id: A0A146WAH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

8078:haao
gene id: 8078:haao
uniprot id: A0A3Q2PU97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

8078:uck2a
gene id: 8078:uck2a
uniprot id: A0A3Q2PH17
names: Similarity
names: Subunit
messages: Belongs to the uridine kinase family.
messages: Homotetramer.

8078:LOC105924628
gene id: 8078:LOC105924628
uniprot id: A0A3Q2T7D2
names: Similarity
messages: Belongs to the ARTD/PARP family.

8078:sema6dl
gene id: 8078:sema6dl
uniprot id: A0A146P6E9
uniprot id: A0A3Q2NRB2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:opn1mw1
gene id: 8078:opn1mw1
uniprot id: A0A146ZY89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8078:LOC105934152
gene id: 8078:LOC105934152
uniprot id: A0A146VVL4
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

8078:nsrp1
gene id: 8078:nsrp1
uniprot id: A0A3Q2SUA3
names: Similarity
messages: Belongs to the NSRP1 family.

8078:gins1
gene id: 8078:gins1
uniprot id: A0A3Q2U8D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

8078:hnf1ba
gene id: 8078:hnf1ba
uniprot id: A0A146VRN3
uniprot id: A0A146VSF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

8078:tmem214
gene id: 8078:tmem214
uniprot id: A0A3Q2TAV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM214 family.
messages: Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.
messages: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:suox
gene id: 8078:suox
uniprot id: A0A3Q2P499
names: Function
messages: Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.

8078:lbr
gene id: 8078:lbr
uniprot id: A0A146ZQH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus inner membrane

8078:ppp6r2a
gene id: 8078:ppp6r2a
uniprot id: A0A3Q2PIW8
names: Similarity
messages: Belongs to the SAPS family.

8078:slc30a5
gene id: 8078:slc30a5
uniprot id: A0A3Q2NXF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Membrane
messages: trans-Golgi network membrane

8078:atp10d
gene id: 8078:atp10d
uniprot id: A0A3Q2QSF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8078:prmt5
gene id: 8078:prmt5
uniprot id: A0A3Q2PPR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Nucleus

8078:lhb
gene id: 8078:lhb
uniprot id: P30972
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

8078:sulf1
gene id: 8078:sulf1
uniprot id: A0A3Q2PSP9
uniprot id: A0A3Q2QUQ0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8078:gap43
gene id: 8078:gap43
uniprot id: A0A3Q2PME7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neuromodulin family.
messages: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
messages: Cell membrane
messages: Membrane
messages: Palmitoylated. Palmitoylation is essential for plasma membrane association.
messages: Synapse
messages: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
messages: filopodium membrane
messages: growth cone membrane

8078:slc41a1
gene id: 8078:slc41a1
uniprot id: A0A3Q2PN60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8078:anp32e
gene id: 8078:anp32e
uniprot id: A0A3Q2QUS3
names: Similarity
messages: Belongs to the ANP32 family.

8078:LOC105938937
gene id: 8078:LOC105938937
uniprot id: A0A146SNF1
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:gng3
gene id: 8078:gng3
uniprot id: A0A3Q2NZX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8078:zgc:103586
gene id: 8078:zgc:103586
uniprot id: A0A3Q2PRG7
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

8078:mos
gene id: 8078:mos
uniprot id: A0A146NRU3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:ildr1a
gene id: 8078:ildr1a
uniprot id: A0A3Q2T447
names: Subcellular Location Annotation
messages: Membrane

8078:gde1
gene id: 8078:gde1
uniprot id: A0A3Q2PFL7
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8078:rev1
gene id: 8078:rev1
uniprot id: A0A3Q2QML8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

8078:ppp2r5cb
gene id: 8078:ppp2r5cb
uniprot id: A0A146Y500
uniprot id: A0A146Y513
uniprot id: A0A146Y579
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8078:polr2i
gene id: 8078:polr2i
uniprot id: A0A3Q2PLH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

8078:LOC105925267
gene id: 8078:LOC105925267
uniprot id: A0A146SIY2
names: Subcellular Location Annotation
messages: Membrane

8078:zgc:73226
gene id: 8078:zgc:73226
uniprot id: A0A3Q2U5I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

8078:tfb2m
gene id: 8078:tfb2m
uniprot id: A0A3Q2UM63
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

8078:inab
gene id: 8078:inab
uniprot id: A0A3Q2R2W3
names: Similarity
messages: Belongs to the intermediate filament family.

8078:LOC105930665
gene id: 8078:LOC105930665
uniprot id: A0A3Q2NVZ7
names: Similarity
messages: Belongs to the UPF0729 family.

8078:memo1
gene id: 8078:memo1
uniprot id: A0A146P7B4
names: Similarity
messages: Belongs to the MEMO1 family.

8078:atp7a
gene id: 8078:atp7a
uniprot id: A0A3Q2P9K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

8078:zgc:92606
gene id: 8078:zgc:92606
uniprot id: A0A3Q2QS79
names: Similarity
messages: Belongs to the ATG8 family.

8078:cxadr
gene id: 8078:cxadr
uniprot id: A0A3Q2UHV3
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105922952
gene id: 8078:LOC105922952
uniprot id: A0A3Q2TME9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8078:LOC105932738
gene id: 8078:LOC105932738
uniprot id: A0A3Q2PDH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

8078:cplane2
gene id: 8078:cplane2
uniprot id: A0A3Q2QYE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
messages: cilium basal body

8078:sgms2a
gene id: 8078:sgms2a
uniprot id: A0A3Q2P061
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

8078:LOC105938142
gene id: 8078:LOC105938142
uniprot id: A0A3Q2NT86
uniprot id: A0A3Q2U002
names: Similarity
messages: Belongs to the CD36 family.

8078:LOC105916194
gene id: 8078:LOC105916194
uniprot id: A0A3Q2TVZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8078:LOC105938050
gene id: 8078:LOC105938050
uniprot id: A0A3Q2SWU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

8078:slc7a9
gene id: 8078:slc7a9
uniprot id: A0A146WII0
names: Subcellular Location Annotation
messages: Membrane

8078:tk1
gene id: 8078:tk1
uniprot id: A0A3Q2PVX2
names: Similarity
messages: Belongs to the thymidine kinase family.

8078:narfl
gene id: 8078:narfl
uniprot id: A0A146P4N5
names: Similarity
messages: Belongs to the NARF family.

8078:zgc:113363
gene id: 8078:zgc:113363
uniprot id: A0A3Q2QUJ7
names: Similarity
messages: Belongs to the MDFI family.

8078:rpl34
gene id: 8078:rpl34
uniprot id: A0A3Q2Q0A0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

8078:LOC105933732
gene id: 8078:LOC105933732
uniprot id: A0A147B2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8078:LOC105918661
gene id: 8078:LOC105918661
uniprot id: A0A3Q2QR41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8078:LOC105916388
gene id: 8078:LOC105916388
uniprot id: A0A3Q2QPZ6
names: Similarity
messages: Belongs to the RRM CPEB family.

8078:LOC105929336
gene id: 8078:LOC105929336
uniprot id: A0A146WK02
uniprot id: A0A147A5K0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8078:pigc
gene id: 8078:pigc
uniprot id: A0A3Q2NMX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

8078:tmem39a
gene id: 8078:tmem39a
uniprot id: A0A3Q2U9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

8078:phf8
gene id: 8078:phf8
uniprot id: A0A3Q2NMD0
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8078:LOC105927848
gene id: 8078:LOC105927848
uniprot id: A0A3Q2UQS6
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:mcama
gene id: 8078:mcama
uniprot id: A0A3Q2R0L3
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105931012
gene id: 8078:LOC105931012
uniprot id: A0A3Q2QIY1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

8078:pthlhb
gene id: 8078:pthlhb
uniprot id: A0A3Q2P1A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8078:naa38
gene id: 8078:naa38
uniprot id: A0A3Q2PQX0
names: Function
names: Similarity
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

8078:LOC105931120
gene id: 8078:LOC105931120
uniprot id: A0A3Q2P0H1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

8078:LOC105931461
gene id: 8078:LOC105931461
uniprot id: A0A3Q2QSH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

8078:LOC105937576
gene id: 8078:LOC105937576
uniprot id: A0A3Q2NME1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

8078:LOC105928900
gene id: 8078:LOC105928900
uniprot id: A0A3Q2NMV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8078:LOC105934238
gene id: 8078:LOC105934238
uniprot id: A0A3Q2UK92
names: Similarity
messages: Belongs to the intermediate filament family.

8078:drd5a
gene id: 8078:drd5a
uniprot id: A0A146P1Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:ogfod1
gene id: 8078:ogfod1
uniprot id: A0A3Q2PCI0
names: Similarity
messages: Belongs to the TPA1 family.

8078:LOC105922996
gene id: 8078:LOC105922996
uniprot id: A0A3Q2UKC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8078:fam122b
gene id: 8078:fam122b
uniprot id: A0A3Q2PLT1
names: Similarity
messages: Belongs to the FAM122 family.

8078:bokb
gene id: 8078:bokb
uniprot id: A0A3Q2Q345
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

8078:si:dkey-6i22.5
gene id: 8078:si:dkey-6i22.5
uniprot id: A0A146NPS0
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

8078:LOC105928804
gene id: 8078:LOC105928804
uniprot id: A0A3Q2Q6Z1
names: Subcellular Location Annotation
messages: Cell membrane

8078:apoob
gene id: 8078:apoob
uniprot id: A0A146YMN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

8078:zgc:91910
gene id: 8078:zgc:91910
uniprot id: A0A3Q2P481
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8078:gosr2
gene id: 8078:gosr2
uniprot id: A0A3Q2QDE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

8078:LOC105925437
gene id: 8078:LOC105925437
uniprot id: A0A3Q2QF42
names: Similarity
messages: Belongs to the arrestin family.

8078:LOC105916242
gene id: 8078:LOC105916242
uniprot id: A0A3Q2PZW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

8078:LOC105928559
gene id: 8078:LOC105928559
uniprot id: A0A147A6A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8078:gpx8
gene id: 8078:gpx8
uniprot id: A0A146P8R0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

8078:bms1
gene id: 8078:bms1
uniprot id: A0A3Q2NU08
names: Subcellular Location Annotation
messages: nucleolus

8078:tcta
gene id: 8078:tcta
uniprot id: A0A146ZXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTA family.
messages: Membrane

8078:upf3b
gene id: 8078:upf3b
uniprot id: A0A146X8F3
names: Similarity
messages: Belongs to the RENT3 family.

8078:pcolcea
gene id: 8078:pcolcea
uniprot id: A0A3Q2QCK5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:colgalt2
gene id: 8078:colgalt2
uniprot id: A0A3Q2Q511
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

8078:cdc25b
gene id: 8078:cdc25b
uniprot id: A0A146ZY34
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

8078:stx11a
gene id: 8078:stx11a
uniprot id: A0A3Q2NPJ3
names: Similarity
messages: Belongs to the syntaxin family.

8078:sars1
gene id: 8078:sars1
uniprot id: A0A3Q2PJD1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

8078:tbl3
gene id: 8078:tbl3
uniprot id: A0A3Q2Q5Q0
names: Subcellular Location Annotation
messages: nucleolus

8078:LOC105921488
gene id: 8078:LOC105921488
uniprot id: A0A146XR51
names: Similarity
messages: Belongs to the ZC3H12 family.

8078:mmp14a
gene id: 8078:mmp14a
uniprot id: A0A3Q2PV69
names: Similarity
messages: Belongs to the peptidase M10A family.

8078:pik3c2g
gene id: 8078:pik3c2g
uniprot id: A0A3Q2QGP1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8078:src
gene id: 8078:src
uniprot id: A0A3Q2PHF7
uniprot id: A0A3Q2TB50
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8078:mrpl52
gene id: 8078:mrpl52
uniprot id: A0A3Q2QY02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

8078:kdm4b
gene id: 8078:kdm4b
uniprot id: A0A3Q2PMD7
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

8078:LOC105926082
gene id: 8078:LOC105926082
uniprot id: A0A3Q2QC93
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2A).
messages: cytosol

8078:trim45
gene id: 8078:trim45
uniprot id: A0A3Q2QL31
names: Similarity
messages: Belongs to the TRIM/RBCC family.

8078:LOC105939261
gene id: 8078:LOC105939261
uniprot id: A0A3Q2R3G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

8078:esr1
gene id: 8078:esr1
uniprot id: A0A3Q2Q3W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer. Can form a heterodimer with ER-beta.
messages: Nucleus
messages: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

8078:prkci
gene id: 8078:prkci
uniprot id: A0A146R973
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

8078:LOC105928245
gene id: 8078:LOC105928245
uniprot id: A0A3Q2QJI1
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8078:LOC105927136
gene id: 8078:LOC105927136
uniprot id: A0A3Q2NZ15
names: Similarity
messages: Belongs to the STRIP family.

8078:atpv0e2
gene id: 8078:atpv0e2
uniprot id: A0A3Q2Q6T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8078:tlr18
gene id: 8078:tlr18
uniprot id: A0A3Q2P652
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8078:LOC105929041
gene id: 8078:LOC105929041
uniprot id: A0A147A584
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

8078:cog1
gene id: 8078:cog1
uniprot id: A0A3Q2QGW3
uniprot id: A0A3Q2U8P8
names: Similarity
messages: Belongs to the COG1 family.

8078:mcamb
gene id: 8078:mcamb
uniprot id: A0A3Q2QBN4
uniprot id: A0A3Q2U3M7
names: Subcellular Location Annotation
messages: Membrane

8078:mllt11
gene id: 8078:mllt11
uniprot id: A0A3Q2PPQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

8078:eloca
gene id: 8078:eloca
uniprot id: A0A3Q2TK59
names: Similarity
messages: Belongs to the SKP1 family.

8078:mpc2b
gene id: 8078:mpc2b
uniprot id: A0A3Q2TBI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

8078:tgfbr1b
gene id: 8078:tgfbr1b
uniprot id: A0A3Q2NZ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8078:LOC105923581
gene id: 8078:LOC105923581
uniprot id: A0A3Q2QXD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8078:LOC105928210
gene id: 8078:LOC105928210
uniprot id: A0A3Q2PBN7
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8078:epha7
gene id: 8078:epha7
uniprot id: A0A3Q2QDK1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:prlrb
gene id: 8078:prlrb
uniprot id: A0A3Q2NV47
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

8078:med25
gene id: 8078:med25
uniprot id: A0A3Q2QAC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 25 family.
messages: Nucleus

8078:LOC105919898
gene id: 8078:LOC105919898
uniprot id: A0A3Q2PKZ2
names: Similarity
messages: Belongs to the MAGUK family.

8078:LOC105938336
gene id: 8078:LOC105938336
uniprot id: A0A3Q2QSG1
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

8078:slc2a13b
gene id: 8078:slc2a13b
uniprot id: A0A146Z4I6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8078:yif1b
gene id: 8078:yif1b
uniprot id: A0A146P5G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

8078:samm50
gene id: 8078:samm50
uniprot id: A0A147AAV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

8078:itgav
gene id: 8078:itgav
uniprot id: A0A3Q2Q6P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8078:cdk2ap2
gene id: 8078:cdk2ap2
uniprot id: A0A3Q2P3Q7
names: Similarity
messages: Belongs to the CDK2AP family.

8078:LOC105916387
gene id: 8078:LOC105916387
uniprot id: A0A146YQ76
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

8078:LOC105934487
gene id: 8078:LOC105934487
uniprot id: A0A3Q2Q8B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

8078:npm1a
gene id: 8078:npm1a
uniprot id: A0A3Q2T8F3
names: Similarity
messages: Belongs to the nucleoplasmin family.

8078:cables2a
gene id: 8078:cables2a
uniprot id: A0A146VMX1
uniprot id: A0A3Q2SVN5
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

8078:dlx2a
gene id: 8078:dlx2a
uniprot id: A0A3Q2NVC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8078:hlfb
gene id: 8078:hlfb
uniprot id: A0A3Q2PWE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

8078:LOC105916366
gene id: 8078:LOC105916366
uniprot id: A0A3Q2TH01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8078:LOC105920556
gene id: 8078:LOC105920556
uniprot id: A0A3Q2PEX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

8078:slc7a2
gene id: 8078:slc7a2
uniprot id: A0A3Q2PKY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8078:nck2a
gene id: 8078:nck2a
uniprot id: A0A3Q2T9K0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

8078:psma8
gene id: 8078:psma8
uniprot id: A0A3Q2PLE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8078:usp30
gene id: 8078:usp30
uniprot id: A0A3Q2PK66
names: Similarity
messages: Belongs to the peptidase C19 family.

8078:LOC105930440
gene id: 8078:LOC105930440
uniprot id: A0A147A2J5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:mak16
gene id: 8078:mak16
uniprot id: A0A3Q2P250
names: Similarity
messages: Belongs to the MAK16 family.

8078:ephb3a
gene id: 8078:ephb3a
uniprot id: A0A3Q2UJK9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:gapdhs
gene id: 8078:gapdhs
uniprot id: A0A3Q2QUD4
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

8078:LOC105918763
gene id: 8078:LOC105918763
uniprot id: A0A3Q2PF84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8078:fgf3
gene id: 8078:fgf3
uniprot id: A0A3Q2R1P1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8078:LOC105930703
gene id: 8078:LOC105930703
uniprot id: A0A3Q2PYS8
names: Subcellular Location Annotation
messages: Nucleus

8078:adam17a
gene id: 8078:adam17a
uniprot id: A0A3Q2QF38
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:ets1
gene id: 8078:ets1
uniprot id: A0A146TT93
uniprot id: A0A147B2S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:akr1a1a
gene id: 8078:akr1a1a
uniprot id: A0A3Q2UBE8
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8078:chrnb1
gene id: 8078:chrnb1
uniprot id: A0A147ASD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8078:onecut3a
gene id: 8078:onecut3a
uniprot id: A0A3Q2PDK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8078:eif3m
gene id: 8078:eif3m
uniprot id: A0A3Q2UNJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8078:cflara
gene id: 8078:cflara
uniprot id: A0A3Q2P6J7
names: Similarity
messages: Belongs to the peptidase C14A family.

8078:lcorl
gene id: 8078:lcorl
uniprot id: A0A3Q2P4L1
names: Subcellular Location Annotation
messages: Nucleus

8078:setd7
gene id: 8078:setd7
uniprot id: A0A3Q2P1K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.
messages: Chromosome
messages: Nucleus

8078:rxfp2a
gene id: 8078:rxfp2a
uniprot id: A0A3Q2Q5T6
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:si:zfos-323e3.4
gene id: 8078:si:zfos-323e3.4
uniprot id: A0A3Q2QFU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8078:nfyal
gene id: 8078:nfyal
uniprot id: A0A146W694
uniprot id: A0A146W901
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

8078:LOC105930722
gene id: 8078:LOC105930722
uniprot id: A0A147A1X1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8078:LOC105916591
gene id: 8078:LOC105916591
uniprot id: A0A147AXG8
names: Similarity
messages: Belongs to the phospholipase D family.

8078:idi1
gene id: 8078:idi1
uniprot id: A0A3Q2PUE0
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

8078:tpd52
gene id: 8078:tpd52
uniprot id: A0A3Q2QN55
names: Similarity
messages: Belongs to the TPD52 family.

8078:irx1b
gene id: 8078:irx1b
uniprot id: A0A3Q2QX86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8078:med6
gene id: 8078:med6
uniprot id: A0A146MXZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8078:tor3a
gene id: 8078:tor3a
uniprot id: A0A146ZQR2
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

8078:faxca
gene id: 8078:faxca
uniprot id: A0A3Q2QHP4
names: Similarity
messages: Belongs to the FAX family.

8078:LOC105918830
gene id: 8078:LOC105918830
uniprot id: A0A3Q2P8L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8078:notch3
gene id: 8078:notch3
uniprot id: A0A3Q2NP27
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

8078:LOC105917425
gene id: 8078:LOC105917425
uniprot id: A0A3Q2PU77
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:tle3a
gene id: 8078:tle3a
uniprot id: A0A146Z2X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8078:mb
gene id: 8078:mb
uniprot id: A0A3Q2P474
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

8078:mmp23ba
gene id: 8078:mmp23ba
uniprot id: A0A146X7R3
names: Caution
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:gdi1
gene id: 8078:gdi1
uniprot id: A0A3Q2PGC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

8078:slc25a35
gene id: 8078:slc25a35
uniprot id: A0A3Q2Q6Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:si:dkey-206f10.1
gene id: 8078:si:dkey-206f10.1
uniprot id: A0A3Q2NNA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8078:polh
gene id: 8078:polh
uniprot id: A0A3Q2Q6T1
names: Subcellular Location Annotation
messages: Nucleus

8078:impdh1b
gene id: 8078:impdh1b
uniprot id: A0A146ZTU3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

8078:txndc5
gene id: 8078:txndc5
uniprot id: A0A3Q2QB18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8078:hadh
gene id: 8078:hadh
uniprot id: A0A3Q2QDA3
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

8078:lix1l
gene id: 8078:lix1l
uniprot id: A0A3Q2QG66
names: Similarity
messages: Belongs to the LIX1 family.

8078:crb1
gene id: 8078:crb1
uniprot id: A0A146YA33
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:polr3h
gene id: 8078:polr3h
uniprot id: A0A3Q2PXV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

8078:LOC105917960
gene id: 8078:LOC105917960
uniprot id: A0A3Q2R3T7
names: Similarity
messages: Belongs to the IL-6 superfamily.

8078:fbln5
gene id: 8078:fbln5
uniprot id: A0A3Q2QBB0
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105939112
gene id: 8078:LOC105939112
uniprot id: A0A3Q2P2H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:zgc:136461
gene id: 8078:zgc:136461
uniprot id: A0A147AN66
names: Subcellular Location Annotation
messages: extracellular space

8078:esr2a
gene id: 8078:esr2a
uniprot id: A0A3Q2PLZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8078:LOC105916182
gene id: 8078:LOC105916182
uniprot id: A0A147AZI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

8078:LOC105918562
gene id: 8078:LOC105918562
uniprot id: A0A3Q2QLK7
names: Subcellular Location Annotation
messages: extracellular space

8078:LOC105921212
gene id: 8078:LOC105921212
uniprot id: A0A3Q2QJB4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:stac
gene id: 8078:stac
uniprot id: A0A147AMH7
uniprot id: A0A3Q2TXE1
names: Subcellular Location Annotation
messages: sarcolemma

8078:e2f4
gene id: 8078:e2f4
uniprot id: A0A3Q2P7L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8078:ankrd13d
gene id: 8078:ankrd13d
uniprot id: A0A3Q2QS36
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

8078:LOC105935408
gene id: 8078:LOC105935408
uniprot id: A0A146VN41
names: Subcellular Location Annotation
messages: Membrane

8078:gabrd
gene id: 8078:gabrd
uniprot id: A0A3Q2PHX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8078:slc12a7b
gene id: 8078:slc12a7b
uniprot id: A0A146W6T7
uniprot id: A0A3Q2P595
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8078:srp14
gene id: 8078:srp14
uniprot id: A0A3Q2QGL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

8078:tmem184a
gene id: 8078:tmem184a
uniprot id: A0A3Q2QR68
names: Subcellular Location Annotation
messages: Membrane

8078:g6pca.1
gene id: 8078:g6pca.1
uniprot id: A0A3Q2PD10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8078:ckba
gene id: 8078:ckba
uniprot id: A0A146VLT5
uniprot id: A2Q010
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8078:grk7b
gene id: 8078:grk7b
uniprot id: A0A3Q2Q7Q0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8078:dpf2
gene id: 8078:dpf2
uniprot id: A0A3Q2NU10
names: Similarity
messages: Belongs to the requiem/DPF family.

8078:gabbr1a
gene id: 8078:gabbr1a
uniprot id: A0A146Y655
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

8078:ctbp1
gene id: 8078:ctbp1
uniprot id: A0A146NX38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

8078:jmjd1cb
gene id: 8078:jmjd1cb
uniprot id: A0A3Q2NW56
names: Subcellular Location Annotation
messages: Nucleus

8078:eif2s1b
gene id: 8078:eif2s1b
uniprot id: A0A3Q2Q8A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

8078:LOC105936145
gene id: 8078:LOC105936145
uniprot id: A0A3Q2T3C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8078:LOC105927044
gene id: 8078:LOC105927044
uniprot id: A0A147A970
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8078:LOC105917189
gene id: 8078:LOC105917189
uniprot id: A0A3Q2TI15
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

8078:nr1h5
gene id: 8078:nr1h5
uniprot id: A0A3Q2QLF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8078:mrpl51
gene id: 8078:mrpl51
uniprot id: A0A3Q2UEF5
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.

8078:hddc2
gene id: 8078:hddc2
uniprot id: A0A3Q2T400
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

8078:LOC105922073
gene id: 8078:LOC105922073
uniprot id: A0A3Q2SN95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

8078:smim7
gene id: 8078:smim7
uniprot id: A0A3Q2P7F2
names: Similarity
messages: Belongs to the SMIM7 family.

8078:tlx2
gene id: 8078:tlx2
uniprot id: A0A3Q2PY25
names: Subcellular Location Annotation
messages: Nucleus

8078:atp5if1b
gene id: 8078:atp5if1b
uniprot id: A0A3Q2NVA4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

8078:gng8
gene id: 8078:gng8
uniprot id: A0A3Q2PN52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8078:LOC105916185
gene id: 8078:LOC105916185
uniprot id: A0A146PGN9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8078:adam8b
gene id: 8078:adam8b
uniprot id: A0A3Q2SUY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105935166
gene id: 8078:LOC105935166
uniprot id: A0A3Q2PCI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

8078:LOC105930506
gene id: 8078:LOC105930506
uniprot id: A0A3Q2QMT8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105929311
gene id: 8078:LOC105929311
uniprot id: A0A3Q2NX75
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

8078:adcy7
gene id: 8078:adcy7
uniprot id: A0A146P416
uniprot id: A0A146P4C2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8078:LOC105920815
gene id: 8078:LOC105920815
uniprot id: A0A3Q2QCW9
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105929772
gene id: 8078:LOC105929772
uniprot id: A0A3Q2PQB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:ddit3
gene id: 8078:ddit3
uniprot id: A0A3Q2PPA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

8078:ahsa1b
gene id: 8078:ahsa1b
uniprot id: A0A3Q2QKB6
names: Similarity
messages: Belongs to the AHA1 family.

8078:kpna1
gene id: 8078:kpna1
uniprot id: A0A146V6A7
names: Similarity
messages: Belongs to the importin alpha family.

8078:LOC105933253
gene id: 8078:LOC105933253
uniprot id: A0A3Q2PJX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

8078:rcl1
gene id: 8078:rcl1
uniprot id: A0A3Q2QKK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.
messages: nucleolus

8078:KEG95 p05
gene id: 8078:KEG95_p05
uniprot id: B7U7W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

8078:lama4
gene id: 8078:lama4
uniprot id: A0A3Q2QL74
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:tspan34
gene id: 8078:tspan34
uniprot id: A0A3Q2UA22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:LOC105918368
gene id: 8078:LOC105918368
uniprot id: A0A3Q2U466
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

8078:LOC105933831
gene id: 8078:LOC105933831
uniprot id: A0A146U6B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

8078:ndufs2
gene id: 8078:ndufs2
uniprot id: A0A3Q2Q3Y4
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

8078:qars1
gene id: 8078:qars1
uniprot id: A0A3Q2SSW7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8078:LOC105928579
gene id: 8078:LOC105928579
uniprot id: A0A146P6N4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

8078:lrrn1
gene id: 8078:lrrn1
uniprot id: A0A3Q2PV71
names: Subcellular Location Annotation
messages: Membrane

8078:slc16a13
gene id: 8078:slc16a13
uniprot id: A0A3Q2SPF6
names: Subcellular Location Annotation
messages: Membrane

8078:plbd1
gene id: 8078:plbd1
uniprot id: A0A3Q2QYL8
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

8078:rhbdl3
gene id: 8078:rhbdl3
uniprot id: A0A146ZWE8
uniprot id: A0A3Q2NVI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

8078:anxa13l
gene id: 8078:anxa13l
uniprot id: A0A3Q2PX98
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8078:LOC105932297
gene id: 8078:LOC105932297
uniprot id: A0A3Q2NS93
names: Similarity
messages: Belongs to the BicD family.

8078:snf8
gene id: 8078:snf8
uniprot id: A0A146P6Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

8078:lhx3
gene id: 8078:lhx3
uniprot id: A0A3Q2QA95
names: Subcellular Location Annotation
messages: Nucleus

8078:gadd45ga
gene id: 8078:gadd45ga
uniprot id: A0A3Q2PU01
names: Similarity
messages: Belongs to the GADD45 family.

8078:dcn
gene id: 8078:dcn
uniprot id: A0A146WCV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN.
messages: May affect the rate of fibrils formation.
messages: extracellular matrix

8078:LOC105926568
gene id: 8078:LOC105926568
uniprot id: A0A3Q2NVE0
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:dusp1
gene id: 8078:dusp1
uniprot id: A0A3Q2U8J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

8078:uck2b
gene id: 8078:uck2b
uniprot id: A0A3Q2QQJ6
names: Similarity
names: Subunit
messages: Belongs to the uridine kinase family.
messages: Homotetramer.

8078:s1pr1
gene id: 8078:s1pr1
uniprot id: A0A146QCC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:LOC105925290
gene id: 8078:LOC105925290
uniprot id: A0A3Q2P8E9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8078:LOC105918013
gene id: 8078:LOC105918013
uniprot id: A0A3Q2QYI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

8078:LOC105930487
gene id: 8078:LOC105930487
uniprot id: A0A3Q2PD67
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8078:hat1
gene id: 8078:hat1
uniprot id: A0A3Q2PJ18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

8078:LOC105934667
gene id: 8078:LOC105934667
uniprot id: A0A3Q2QVL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:gucy1b1
gene id: 8078:gucy1b1
uniprot id: A0A3Q2Q0G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

8078:phospho2
gene id: 8078:phospho2
uniprot id: A0A3Q2PCE5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

8078:tcf7l2
gene id: 8078:tcf7l2
uniprot id: A0A3Q2QSA1
uniprot id: A0A3Q2TER9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8078:dph6
gene id: 8078:dph6
uniprot id: A0A3Q2QYS5
names: Similarity
messages: Belongs to the Diphthine--ammonia ligase family.

8078:calua
gene id: 8078:calua
uniprot id: A0A146VID8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus
messages: Melanosome
messages: Membrane
messages: Sarcoplasmic reticulum lumen
messages: Secreted

8078:baz1b
gene id: 8078:baz1b
uniprot id: A0A146PA69
names: Subcellular Location Annotation
messages: Nucleus

8078:mapta
gene id: 8078:mapta
uniprot id: A0A3Q2QHH9
uniprot id: A0A3Q2QJ81
names: Subcellular Location Annotation
messages: cytoskeleton

8078:sfmbt1
gene id: 8078:sfmbt1
uniprot id: A0A3Q2SVI8
names: Subcellular Location Annotation
messages: Nucleus

8078:epd
gene id: 8078:epd
uniprot id: A0A147A4N5
names: Similarity
messages: Belongs to the ependymin family.

8078:sema6bb
gene id: 8078:sema6bb
uniprot id: A0A3Q2NPN4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:nkain1
gene id: 8078:nkain1
uniprot id: A0A3Q2P4L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

8078:c11h11orf54
gene id: 8078:c11h11orf54
uniprot id: A0A3Q2QDT5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

8078:hk2
gene id: 8078:hk2
uniprot id: A0A146P523
uniprot id: A0A3Q2P0L3
names: Similarity
messages: Belongs to the hexokinase family.

8078:ccnl1a
gene id: 8078:ccnl1a
uniprot id: A0A3Q2NPC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin L subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus speckle
messages: nucleoplasm

8078:galnt7
gene id: 8078:galnt7
uniprot id: A0A3Q2NUV0
uniprot id: A0A3Q2NUY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8078:si:ch1073-358c10.1
gene id: 8078:si:ch1073-358c10.1
uniprot id: A0A3Q2P1H7
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

8078:srsf5b
gene id: 8078:srsf5b
uniprot id: A0A3Q2QGN7
names: Similarity
messages: Belongs to the splicing factor SR family.

8078:galnt2
gene id: 8078:galnt2
uniprot id: A0A3Q2P9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8078:prkab1b
gene id: 8078:prkab1b
uniprot id: A0A3Q2Q3L6
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

8078:mt2
gene id: 8078:mt2
uniprot id: B1B604
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

8078:mtrf1l
gene id: 8078:mtrf1l
uniprot id: A0A146MSJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

8078:LOC105936216
gene id: 8078:LOC105936216
uniprot id: A0A3Q2QFX5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

8078:eif2b4
gene id: 8078:eif2b4
uniprot id: A0A3Q2PWW0
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

8078:slc18b1
gene id: 8078:slc18b1
uniprot id: A0A3Q2NPD8
names: Subcellular Location Annotation
messages: Membrane

8078:gnpnat1
gene id: 8078:gnpnat1
uniprot id: A0A146WGM9
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

8078:maco1a
gene id: 8078:maco1a
uniprot id: A0A3Q2QY81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

8078:LOC105926971
gene id: 8078:LOC105926971
uniprot id: A0A3Q2T670
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: axon
messages: cytoskeleton

8078:LOC105917717
gene id: 8078:LOC105917717
uniprot id: A0A3Q2U9H0
names: Similarity
messages: Belongs to the GADD45 family.

8078:LOC105927361
gene id: 8078:LOC105927361
uniprot id: A0A3Q2TJY2
names: Subcellular Location Annotation
messages: Mitochondrion

8078:nfkb1
gene id: 8078:nfkb1
uniprot id: A0A3Q2PLD2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8078:ing5a
gene id: 8078:ing5a
uniprot id: A0A147A5T1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8078:mat2al
gene id: 8078:mat2al
uniprot id: A0A3Q2QDE5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

8078:mtf2
gene id: 8078:mtf2
uniprot id: A0A146P708
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

8078:LOC105933853
gene id: 8078:LOC105933853
uniprot id: A0A3Q2SWQ6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

8078:nrf1
gene id: 8078:nrf1
uniprot id: A0A146P3W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

8078:tat
gene id: 8078:tat
uniprot id: A0A3Q2QHF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

8078:si:ch211-161c3.6
gene id: 8078:si:ch211-161c3.6
uniprot id: A0A146ZW62
names: Similarity
messages: Belongs to the HMGA family.

8078:clic2
gene id: 8078:clic2
uniprot id: A0A3Q2QWN3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8078:LOC105935470
gene id: 8078:LOC105935470
uniprot id: A0A3Q2TCC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8078:hdac8
gene id: 8078:hdac8
uniprot id: A0A146NLK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility. In addition to protein deacetylase activity, also has protein-lysine deacylase activity: acts as a protein decrotonylase by mediating decrotonylation ((2E)-butenoyl) of histones.
messages: Nucleus

8078:pin4
gene id: 8078:pin4
uniprot id: A0A146NKX5
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

8078:tekt2
gene id: 8078:tekt2
uniprot id: A0A3Q2QS73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8078:u2af2a
gene id: 8078:u2af2a
uniprot id: A0A146VPP9
uniprot id: A0A3Q2PM90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

8078:si:ch1073-396h14.1
gene id: 8078:si:ch1073-396h14.1
uniprot id: A0A3Q2NVI0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:tomm20a
gene id: 8078:tomm20a
uniprot id: A0A146NVF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

8078:LOC105930152
gene id: 8078:LOC105930152
uniprot id: A0A3Q2UGH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

8078:aldh9a1b
gene id: 8078:aldh9a1b
uniprot id: A0A146X9N8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8078:st3gal2
gene id: 8078:st3gal2
uniprot id: A0A3Q2PR14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8078:nt5dc3
gene id: 8078:nt5dc3
uniprot id: A0A3Q2P4W8
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

8078:cndp2
gene id: 8078:cndp2
uniprot id: A0A3Q2U9J2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

8078:cenpj
gene id: 8078:cenpj
uniprot id: A0A3Q2TCZ9
names: Similarity
messages: Belongs to the TCP10 family.

8078:map3k8
gene id: 8078:map3k8
uniprot id: A0A3Q2P396
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8078:camsap3
gene id: 8078:camsap3
uniprot id: A0A146ZPU5
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8078:LOC105931871
gene id: 8078:LOC105931871
uniprot id: A0A3Q2NTX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

8078:minpp1a
gene id: 8078:minpp1a
uniprot id: A0A3Q2NQL3
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

8078:get3
gene id: 8078:get3
uniprot id: A0A146WAJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer.

8078:c18h19orf54
gene id: 8078:c18h19orf54
uniprot id: A0A3Q2NZV6
names: Similarity
messages: Belongs to the UPF0692 family.

8078:thap1
gene id: 8078:thap1
uniprot id: A0A146ZQ79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

8078:nipa2
gene id: 8078:nipa2
uniprot id: A0A146X8W6
uniprot id: A0A3Q2PCG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8078:LOC105922977
gene id: 8078:LOC105922977
uniprot id: A0A3Q2UKE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

8078:ptpa
gene id: 8078:ptpa
uniprot id: A0A146P527
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8078:marcksa
gene id: 8078:marcksa
uniprot id: A0A3Q2PRX3
names: Similarity
messages: Belongs to the MARCKS family.

8078:LOC105931489
gene id: 8078:LOC105931489
uniprot id: A0A147A0Q2
names: Similarity
messages: Belongs to the TOM1 family.

8078:LOC105936827
gene id: 8078:LOC105936827
uniprot id: A0A146VES9
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8078:nup35
gene id: 8078:nup35
uniprot id: A0A146ZMK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

8078:hoxa11a
gene id: 8078:hoxa11a
uniprot id: A0A146Q311
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8078:LOC105921746
gene id: 8078:LOC105921746
uniprot id: A0A3Q2UPR9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8078:LOC105937237
gene id: 8078:LOC105937237
uniprot id: A0A3Q2NUA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8078:cops6
gene id: 8078:cops6
uniprot id: A0A3Q2QST2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN6 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.
messages: Cytoplasm
messages: Nucleus

8078:usp12b
gene id: 8078:usp12b
uniprot id: A0A3Q2PX56
names: Similarity
messages: Belongs to the peptidase C19 family.

8078:LOC105925946
gene id: 8078:LOC105925946
uniprot id: A0A3Q2QF07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also functions as deacetylase for non-histone proteins.
messages: Nucleus

8078:gsk3ab
gene id: 8078:gsk3ab
uniprot id: A0A146P6Z1
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

8078:LOC105920605
gene id: 8078:LOC105920605
uniprot id: A0A3Q2NZZ5
names: Similarity
messages: Belongs to the PAIP2 family.

8078:kif22
gene id: 8078:kif22
uniprot id: A0A3Q2PIP5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8078:ankrd13a
gene id: 8078:ankrd13a
uniprot id: A0A3Q2PJB5
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

8078:LOC105926024
gene id: 8078:LOC105926024
uniprot id: A0A3Q2NZ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.
messages: Membrane
messages: Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins (By similarity). Plays a role in pronephric kidney tubule development.

8078:mlec
gene id: 8078:mlec
uniprot id: A0A3Q2R272
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:cspg4b
gene id: 8078:cspg4b
uniprot id: A0A3Q2U3L0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:srsf1b
gene id: 8078:srsf1b
uniprot id: A0A3Q2PQS5
names: Similarity
messages: Belongs to the splicing factor SR family.

8078:alg5
gene id: 8078:alg5
uniprot id: A0A3Q2Q6G8
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

8078:ctsl.1
gene id: 8078:ctsl.1
uniprot id: A0A3Q2P1J7
names: Similarity
messages: Belongs to the peptidase C1 family.

8078:dpt
gene id: 8078:dpt
uniprot id: A0A3Q2QJS2
names: Similarity
messages: Belongs to the dermatopontin family.

8078:cyldb
gene id: 8078:cyldb
uniprot id: A0A3Q2TKU9
names: Subcellular Location Annotation
messages: centrosome
messages: perinuclear region

8078:slit1a
gene id: 8078:slit1a
uniprot id: A0A3Q2Q8C9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:alg12
gene id: 8078:alg12
uniprot id: A0A3Q2QD30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:LOC105936935
gene id: 8078:LOC105936935
uniprot id: A0A3Q2NNR4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

8078:ppm1nb
gene id: 8078:ppm1nb
uniprot id: A0A3Q2NP02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8078:LOC105926201
gene id: 8078:LOC105926201
uniprot id: A0A147AAV7
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

8078:ctbp2l
gene id: 8078:ctbp2l
uniprot id: A0A3Q2PCF4
uniprot id: A0A3Q2PCV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

8078:si:ch1073-390k14.1
gene id: 8078:si:ch1073-390k14.1
uniprot id: A0A3Q2SQT0
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

8078:LOC105925575
gene id: 8078:LOC105925575
uniprot id: A0A147AD84
names: Similarity
messages: Belongs to the ependymin family.

8078:acta2
gene id: 8078:acta2
uniprot id: A0A147AZ76
names: Similarity
messages: Belongs to the actin family.

8078:LOC105933119
gene id: 8078:LOC105933119
uniprot id: A0A3Q2QZ54
names: Similarity
messages: Belongs to the VPS13 family.

8078:fam133b
gene id: 8078:fam133b
uniprot id: A0A3Q2PF73
names: Similarity
messages: Belongs to the FAM133 family.

8078:dpagt1
gene id: 8078:dpagt1
uniprot id: A0A3Q2NTP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:plekha8
gene id: 8078:plekha8
uniprot id: A0A3Q2PLN0
names: Subcellular Location Annotation
messages: Membrane
messages: trans-Golgi network membrane

8078:dcst2
gene id: 8078:dcst2
uniprot id: A0A3Q2PTS9
names: Subcellular Location Annotation
messages: Membrane

8078:lrrc4ba
gene id: 8078:lrrc4ba
uniprot id: A0A3Q2QAB3
names: Subcellular Location Annotation
messages: Membrane

8078:lcat
gene id: 8078:lcat
uniprot id: A0A3Q2QM13
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

8078:mon1bb
gene id: 8078:mon1bb
uniprot id: A0A3Q2QWI0
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

8078:aspn
gene id: 8078:aspn
uniprot id: A0A3Q2PRZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: extracellular matrix

8078:pvalb3
gene id: 8078:pvalb3
uniprot id: C0LEL6
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8078:mrpl20
gene id: 8078:mrpl20
uniprot id: A0A3Q2U270
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

8078:arsb
gene id: 8078:arsb
uniprot id: A0A147AU30
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8078:LOC105932943
gene id: 8078:LOC105932943
uniprot id: A0A3Q2QAE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

8078:LOC105930934
gene id: 8078:LOC105930934
uniprot id: A0A147A1H4
uniprot id: A0A3Q2PHL5
uniprot id: A0A3Q2PHN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

8078:aldoca
gene id: 8078:aldoca
uniprot id: A0A146ZUF4
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

8078:cnnm2b
gene id: 8078:cnnm2b
uniprot id: A0A147AUY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

8078:LOC105937928
gene id: 8078:LOC105937928
uniprot id: A0A146ZML4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:LOC105935514
gene id: 8078:LOC105935514
uniprot id: A0A3Q2UBI3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8078:daxx
gene id: 8078:daxx
uniprot id: A0A3Q2QJ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAXX family.
messages: Cytoplasm
messages: PML body
messages: centromere
messages: nucleolus
messages: nucleoplasm

8078:zgc:158296
gene id: 8078:zgc:158296
uniprot id: A0A3Q2TD01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

8078:ube2kb
gene id: 8078:ube2kb
uniprot id: A0A146PH93
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:LOC105927331
gene id: 8078:LOC105927331
uniprot id: A0A146R1T2
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

8078:LOC105933445
gene id: 8078:LOC105933445
uniprot id: A0A3Q2P4Q2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8078:epn1
gene id: 8078:epn1
uniprot id: A0A3Q2PLW2
names: Similarity
messages: Belongs to the epsin family.

8078:kcnk3a
gene id: 8078:kcnk3a
uniprot id: A0A3Q2R2T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8078:si:dkeyp-69e1.8
gene id: 8078:si:dkeyp-69e1.8
uniprot id: A0A3Q2P974
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8078:psenen
gene id: 8078:psenen
uniprot id: A0A146N3X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Golgi stack membrane
messages: Membrane

8078:etv5a
gene id: 8078:etv5a
uniprot id: A0A3Q2NPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:LOC105920925
gene id: 8078:LOC105920925
uniprot id: A0A3Q2NYE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:LOC105926421
gene id: 8078:LOC105926421
uniprot id: A0A3Q2PD08
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105920382
gene id: 8078:LOC105920382
uniprot id: A0A3Q2TFU5
names: Subcellular Location Annotation
messages: Cytoplasm

8078:ucmab
gene id: 8078:ucmab
uniprot id: A0A3Q2SZD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

8078:enkd1
gene id: 8078:enkd1
uniprot id: A0A3Q2T1Z4
names: Subcellular Location Annotation
messages: cilium axoneme

8078:smarca4a
gene id: 8078:smarca4a
uniprot id: A0A3Q2QK18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8078:zgc:154046
gene id: 8078:zgc:154046
uniprot id: A0A3Q2NP52
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8078:tmem98
gene id: 8078:tmem98
uniprot id: A0A147AY76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

8078:si:dkey-206d17.12
gene id: 8078:si:dkey-206d17.12
uniprot id: A0A3Q2NNE9
names: Similarity
messages: Belongs to the ZC3H12 family.

8078:LOC105937414
gene id: 8078:LOC105937414
uniprot id: A0A146ZNM5
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

8078:tie1
gene id: 8078:tie1
uniprot id: A0A3Q2NP85
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:cfap298
gene id: 8078:cfap298
uniprot id: A0A3Q2QUK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

8078:ncam1b
gene id: 8078:ncam1b
uniprot id: A0A3Q2NTG1
uniprot id: A0A3Q2NTW7
uniprot id: A0A3Q2U020
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

8078:trappc4
gene id: 8078:trappc4
uniprot id: A0A146NEI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

8078:LOC105931019
gene id: 8078:LOC105931019
uniprot id: A0A146WD86
uniprot id: A0A3Q2P8V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8078:pdha1b
gene id: 8078:pdha1b
uniprot id: A0A3Q2P142
uniprot id: A0A3Q2QCJ1
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

8078:mnx1
gene id: 8078:mnx1
uniprot id: A0A147AUH9
names: Subcellular Location Annotation
messages: Nucleus

8078:wscd1b
gene id: 8078:wscd1b
uniprot id: A0A147A395
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Membrane

8078:eif3g
gene id: 8078:eif3g
uniprot id: A0A146ZNS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

8078:LOC105925301
gene id: 8078:LOC105925301
uniprot id: A0A3Q2QR33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

8078:LOC105932551
gene id: 8078:LOC105932551
uniprot id: A0A146ZYF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:LOC105930989
gene id: 8078:LOC105930989
uniprot id: A0A3Q2PDM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8078:LOC105935675
gene id: 8078:LOC105935675
uniprot id: A0A3Q2Q9J2
uniprot id: A0A3Q2QAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

8078:LOC105919145
gene id: 8078:LOC105919145
uniprot id: A0A3Q2Q1S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane

8078:cltrn
gene id: 8078:cltrn
uniprot id: A0A3Q2QP07
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105939090
gene id: 8078:LOC105939090
uniprot id: A0A146ZKA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8078:avl9
gene id: 8078:avl9
uniprot id: A0A3Q2NUV4
names: Subcellular Location Annotation
messages: Endosome
messages: Recycling endosome

8078:pik3r1
gene id: 8078:pik3r1
uniprot id: A0A3Q2NRX4
uniprot id: A0A3Q2Q6Y5
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

8078:jph1a
gene id: 8078:jph1a
uniprot id: A0A146XRX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

8078:mpp1
gene id: 8078:mpp1
uniprot id: A0A3Q2QCP6
names: Similarity
messages: Belongs to the MAGUK family.

8078:nfu1
gene id: 8078:nfu1
uniprot id: A0A3Q2PVV1
names: Similarity
messages: Belongs to the NifU family.

8078:gnb3a
gene id: 8078:gnb3a
uniprot id: A0A147A199
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8078:LOC105930242
gene id: 8078:LOC105930242
uniprot id: A0A3Q2QWC2
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

8078:plbd2
gene id: 8078:plbd2
uniprot id: A0A3Q2PCT5
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

8078:epor
gene id: 8078:epor
uniprot id: A0A3Q2T2B8
names: Subcellular Location Annotation
messages: Membrane

8078:rps4x
gene id: 8078:rps4x
uniprot id: A0A3Q2PVB5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

8078:dnaaf4
gene id: 8078:dnaaf4
uniprot id: A0A3Q2PSQ4
names: Subcellular Location Annotation
messages: Dynein axonemal particle
messages: neuron projection

8078:cct8
gene id: 8078:cct8
uniprot id: A0A146Y257
uniprot id: A0A146Y3K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

8078:acta1b
gene id: 8078:acta1b
uniprot id: A0A3Q2P9J5
names: Similarity
messages: Belongs to the actin family.

8078:tert
gene id: 8078:tert
uniprot id: A0A3Q2Q2U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

8078:fli1
gene id: 8078:fli1
uniprot id: A0A3Q2QTT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:pard3ba
gene id: 8078:pard3ba
uniprot id: A0A3Q2R192
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

8078:sumo1
gene id: 8078:sumo1
uniprot id: A0A3Q2PQG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8078:crk
gene id: 8078:crk
uniprot id: A0A3Q2Q311
names: Similarity
messages: Belongs to the CRK family.

8078:hspb9
gene id: 8078:hspb9
uniprot id: A0A3Q2R3B4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8078:baz1a
gene id: 8078:baz1a
uniprot id: A0A3Q2NWZ7
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105918882
gene id: 8078:LOC105918882
uniprot id: A0A3Q2QDN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

8078:wars1
gene id: 8078:wars1
uniprot id: A0A3Q2NZA2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8078:zgc:174164
gene id: 8078:zgc:174164
uniprot id: A0A3Q2PCD2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:tango6
gene id: 8078:tango6
uniprot id: A0A3Q2QTG5
names: Similarity
messages: Belongs to the Tango6 family.

8078:LOC105930399
gene id: 8078:LOC105930399
uniprot id: A0A3Q2PIT4
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

8078:xirp2b
gene id: 8078:xirp2b
uniprot id: A0A146XRH5
names: Domain
names: Similarity
messages: Belongs to the Xin family.
messages: Xin repeats bind F-actin.

8078:epcam
gene id: 8078:epcam
uniprot id: A0A3Q2R1J1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:serp2
gene id: 8078:serp2
uniprot id: A0A3Q2QIR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

8078:tprkb
gene id: 8078:tprkb
uniprot id: A0A3Q2Q995
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

8078:polg2
gene id: 8078:polg2
uniprot id: A0A3Q2PGG3
names: Subcellular Location Annotation
messages: Mitochondrion

8078:azin1b
gene id: 8078:azin1b
uniprot id: A0A3Q2UFG2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

8078:LOC105932358
gene id: 8078:LOC105932358
uniprot id: A0A3Q2NS51
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:mtrf1
gene id: 8078:mtrf1
uniprot id: A0A3Q2TLR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

8078:slc16a2
gene id: 8078:slc16a2
uniprot id: A0A3Q2TZE8
names: Subcellular Location Annotation
messages: Membrane

8078:fntb
gene id: 8078:fntb
uniprot id: A0A147B1B9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

8078:LOC105939396
gene id: 8078:LOC105939396
uniprot id: A0A3Q2QXG1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:agpat4
gene id: 8078:agpat4
uniprot id: A0A3Q2SYY4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8078:eif4ea
gene id: 8078:eif4ea
uniprot id: A0A3Q2T0T9
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

8078:LOC105930800
gene id: 8078:LOC105930800
uniprot id: A0A3Q2PTP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

8078:LOC105921230
gene id: 8078:LOC105921230
uniprot id: A0A3Q2T4V3
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

8078:fbxo32
gene id: 8078:fbxo32
uniprot id: A0A3Q2NVM1
names: Subcellular Location Annotation
messages: Nucleus

8078:ubn2b
gene id: 8078:ubn2b
uniprot id: A0A3Q2P8R8
uniprot id: A0A3Q2P8T2
names: Similarity
messages: Belongs to the ubinuclein family.

8078:LOC105921509
gene id: 8078:LOC105921509
uniprot id: A0A147AM25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

8078:sfmbt2
gene id: 8078:sfmbt2
uniprot id: A0A146ZQ06
names: Subcellular Location Annotation
messages: Nucleus

8078:zfp36l2
gene id: 8078:zfp36l2
uniprot id: A0A3Q2PXW0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8078:zgc:162730
gene id: 8078:zgc:162730
uniprot id: A0A146P735
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8078:LOC105917326
gene id: 8078:LOC105917326
uniprot id: A0A3Q2Q259
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

8078:tm4sf18
gene id: 8078:tm4sf18
uniprot id: A0A3Q2NT92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8078:ches1
gene id: 8078:ches1
uniprot id: A0A3Q2SV47
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105933878
gene id: 8078:LOC105933878
uniprot id: A0A147B2R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

8078:LOC105933218
gene id: 8078:LOC105933218
uniprot id: A0A146ZY74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8078:tbxtb
gene id: 8078:tbxtb
uniprot id: A0A147AHD6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:rbbp8
gene id: 8078:rbbp8
uniprot id: A0A3Q2PYF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

8078:adck5
gene id: 8078:adck5
uniprot id: A0A146QHW6
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8078:dntt
gene id: 8078:dntt
uniprot id: A0A3Q2R089
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus
messages: Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.

8078:LOC105933324
gene id: 8078:LOC105933324
uniprot id: A0A146RLI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

8078:LOC105938561
gene id: 8078:LOC105938561
uniprot id: Q5J7A1
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:il1rapl1a
gene id: 8078:il1rapl1a
uniprot id: A0A3Q2QLQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: Membrane

8078:spast
gene id: 8078:spast
uniprot id: A0A3Q2TUE9
names: Similarity
messages: Belongs to the AAA ATPase family.

8078:LOC105937422
gene id: 8078:LOC105937422
uniprot id: A0A3Q2NN80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

8078:LOC105931341
gene id: 8078:LOC105931341
uniprot id: A0A3Q2R0E2
names: Subcellular Location Annotation
messages: Nucleus

8078:copz1
gene id: 8078:copz1
uniprot id: A0A3Q2Q570
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

8078:si:ch211-79k12.1
gene id: 8078:si:ch211-79k12.1
uniprot id: A0A3Q2PCV7
names: Subcellular Location Annotation
messages: Membrane

8078:elmo3
gene id: 8078:elmo3
uniprot id: A0A146Z0Q6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

8078:sirt4
gene id: 8078:sirt4
uniprot id: A0A3Q2PKR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

8078:zgc:101583
gene id: 8078:zgc:101583
uniprot id: A0A3Q2PJM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8078:ccnd3
gene id: 8078:ccnd3
uniprot id: A0A3Q2NXR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8078:LOC105915544
gene id: 8078:LOC105915544
uniprot id: A0A3Q2NT89
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

8078:lars2
gene id: 8078:lars2
uniprot id: A0A3Q2NQ03
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8078:vrtn
gene id: 8078:vrtn
uniprot id: A0A3Q2PWM4
names: Similarity
messages: Belongs to the vertnin family.

8078:LOC105934824
gene id: 8078:LOC105934824
uniprot id: A0A3Q2PV87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

8078:ndufa13
gene id: 8078:ndufa13
uniprot id: A0A3Q2SR94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

8078:phkb
gene id: 8078:phkb
uniprot id: A0A3Q2NPF3
uniprot id: A0A3Q2TXG6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

8078:phactr2
gene id: 8078:phactr2
uniprot id: A0A3Q2PWW3
uniprot id: A0A3Q2QZ32
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

8078:nbn
gene id: 8078:nbn
uniprot id: A0A3Q2QWD4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
messages: Component of the MRN complex.
messages: Nucleus
messages: telomere

8078:LOC105917265
gene id: 8078:LOC105917265
uniprot id: A0A147AW38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

8078:LOC105927236
gene id: 8078:LOC105927236
uniprot id: A0A3Q2NU37
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8078:LOC105916364
gene id: 8078:LOC105916364
uniprot id: A0A3Q2PR81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8078:LOC105934578
gene id: 8078:LOC105934578
uniprot id: A0A146RFK0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Cytoplasmic granule membrane
messages: Membrane
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

8078:npy7r
gene id: 8078:npy7r
uniprot id: A0A3Q2QHC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:si:ch1073-335m2.2
gene id: 8078:si:ch1073-335m2.2
uniprot id: A0A3Q2NW52
names: Similarity
messages: Belongs to the RRM Spen family.

8078:tmem177
gene id: 8078:tmem177
uniprot id: A0A146P6S7
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

8078:si:dkey-4e7.3
gene id: 8078:si:dkey-4e7.3
uniprot id: A0A3Q2PES3
names: Similarity
messages: Belongs to the IUNH family.

8078:rpl35
gene id: 8078:rpl35
uniprot id: A0A3Q2TT65
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

8078:mbtps2
gene id: 8078:mbtps2
uniprot id: A0A3Q2PEP1
names: Similarity
messages: Belongs to the peptidase M50A family.

8078:sec24a
gene id: 8078:sec24a
uniprot id: A0A146P525
uniprot id: A0A146V1D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8078:smpdl3a
gene id: 8078:smpdl3a
uniprot id: A0A3Q2Q5G0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

8078:arsia
gene id: 8078:arsia
uniprot id: A0A3Q2QFH0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8078:hmox2b
gene id: 8078:hmox2b
uniprot id: A0A147B3T5
names: Similarity
messages: Belongs to the heme oxygenase family.

8078:pbx3b
gene id: 8078:pbx3b
uniprot id: A0A147A5T8
uniprot id: A0A3Q2NPG5
uniprot id: A0A3Q2NPK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8078:chrna9a
gene id: 8078:chrna9a
uniprot id: A0A3Q2U7E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8078:tomm40l
gene id: 8078:tomm40l
uniprot id: A0A3Q2TE36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

8078:KEG95 p07
gene id: 8078:KEG95_p07
uniprot id: B7U7V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

8078:LOC105929039
gene id: 8078:LOC105929039
uniprot id: A0A147A5D3
names: Subcellular Location Annotation
messages: Membrane

8078:gdi2
gene id: 8078:gdi2
uniprot id: A0A3Q2QQR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

8078:esrrgb
gene id: 8078:esrrgb
uniprot id: Q2I6X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8078:LOC105939149
gene id: 8078:LOC105939149
uniprot id: A0A3Q2Q3A8
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

8078:ndufb8
gene id: 8078:ndufb8
uniprot id: A0A3Q2QLT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8078:LOC105934126
gene id: 8078:LOC105934126
uniprot id: A0A3Q2NP06
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:msna
gene id: 8078:msna
uniprot id: A0A3Q2Q7Z5
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8078:efna5a
gene id: 8078:efna5a
uniprot id: A0A3Q2PJ38
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:bace2
gene id: 8078:bace2
uniprot id: A0A3Q2Q4C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane

8078:LOC105934284
gene id: 8078:LOC105934284
uniprot id: A0A3Q2QNS8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

8078:LOC105938445
gene id: 8078:LOC105938445
uniprot id: A0A3Q2UFF0
names: Subcellular Location Annotation
messages: extracellular space

8078:slc35a1
gene id: 8078:slc35a1
uniprot id: A0A3Q2QZU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

8078:ltbp3
gene id: 8078:ltbp3
uniprot id: A0A146P647
uniprot id: A0A3Q2QBY9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8078:adprhl1
gene id: 8078:adprhl1
uniprot id: A0A3Q2P8Q1
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

8078:cluap1
gene id: 8078:cluap1
uniprot id: A0A146P5V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

8078:cd9a
gene id: 8078:cd9a
uniprot id: A0A3Q2Q8M2
uniprot id: A0A3Q2U177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:gcgb
gene id: 8078:gcgb
uniprot id: A0A3Q2Q486
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8078:dtx1
gene id: 8078:dtx1
uniprot id: A0A147A5U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8078:hmx3a
gene id: 8078:hmx3a
uniprot id: A0A3Q2QZW4
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105927217
gene id: 8078:LOC105927217
uniprot id: A0A3Q2P0D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8078:LOC105939195
gene id: 8078:LOC105939195
uniprot id: A0A3Q2SUC5
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8078:LOC105936418
gene id: 8078:LOC105936418
uniprot id: A0A146ZQM5
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8078:mturn
gene id: 8078:mturn
uniprot id: A0A146ZZF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

8078:dcaf13
gene id: 8078:dcaf13
uniprot id: A0A3Q2T3Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

8078:rps19
gene id: 8078:rps19
uniprot id: A0A3Q2T7B9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

8078:ezh1
gene id: 8078:ezh1
uniprot id: A0A3Q2SY46
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105925467
gene id: 8078:LOC105925467
uniprot id: A0A3Q2P3L0
names: Subcellular Location Annotation
messages: Nucleus

8078:aqp11
gene id: 8078:aqp11
uniprot id: A0A3Q2QG95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

8078:pim3
gene id: 8078:pim3
uniprot id: A0A3Q2U5M2
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8078:letm2
gene id: 8078:letm2
uniprot id: A0A3Q2UPS9
names: Subcellular Location Annotation
messages: Membrane

8078:sept3
gene id: 8078:sept3
uniprot id: A0A3Q2NXS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm

8078:LOC105938786
gene id: 8078:LOC105938786
uniprot id: A0A3Q2PZK7
names: Similarity
messages: Belongs to the yippee family.

8078:tspo
gene id: 8078:tspo
uniprot id: A0A3Q2PLS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

8078:LOC105917705
gene id: 8078:LOC105917705
uniprot id: A0A3Q2PAJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

8078:tnfrsfa
gene id: 8078:tnfrsfa
uniprot id: A0A3Q2PZD5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:kcnn3
gene id: 8078:kcnn3
uniprot id: A0A147A6E9
names: Subcellular Location Annotation
messages: Membrane

8078:papss1
gene id: 8078:papss1
uniprot id: A0A146P546
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

8078:fam120c
gene id: 8078:fam120c
uniprot id: A0A146QXI9
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

8078:scg2b
gene id: 8078:scg2b
uniprot id: A0A3Q2QVV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

8078:LOC105940369
gene id: 8078:LOC105940369
uniprot id: A0A3Q2QTB7
names: Subcellular Location Annotation
messages: Membrane

8078:washc3
gene id: 8078:washc3
uniprot id: A0A147A141
names: Similarity
messages: Belongs to the CCDC53 family.

8078:zgc:101540
gene id: 8078:zgc:101540
uniprot id: A0A3Q2QIS4
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8078:desma
gene id: 8078:desma
uniprot id: A0A3Q2P3Y0
names: Similarity
messages: Belongs to the intermediate filament family.

8078:stc1
gene id: 8078:stc1
uniprot id: A0A3Q2TLQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

8078:shcbp1
gene id: 8078:shcbp1
uniprot id: A0A3Q2PU68
names: Subcellular Location Annotation
messages: spindle

8078:cryba1l1
gene id: 8078:cryba1l1
uniprot id: A0A3Q2UGY1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8078:dgkab
gene id: 8078:dgkab
uniprot id: A0A3Q2P2J4
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8078:mfsd4b
gene id: 8078:mfsd4b
uniprot id: A0A3Q2T616
names: Subcellular Location Annotation
messages: Membrane

8078:jpt1a
gene id: 8078:jpt1a
uniprot id: A0A3Q2Q851
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

8078:LOC105933420
gene id: 8078:LOC105933420
uniprot id: A0A146ZWQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

8078:LOC105935439
gene id: 8078:LOC105935439
uniprot id: A0A3Q2PLU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 7B2 family.
messages: Secreted

8078:atp1b4
gene id: 8078:atp1b4
uniprot id: A0A3Q2TIS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8078:tada2b
gene id: 8078:tada2b
uniprot id: A0A147AXT8
names: Subcellular Location Annotation
messages: Nucleus

8078:ldha
gene id: 8078:ldha
uniprot id: Q92055
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.
messages: Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).

8078:uba3
gene id: 8078:uba3
uniprot id: A0A3Q2QAI7
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

8078:gpr155a
gene id: 8078:gpr155a
uniprot id: A0A3Q2QAZ2
names: Subcellular Location Annotation
messages: Membrane

8078:apeh
gene id: 8078:apeh
uniprot id: A0A3Q2PWI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

8078:dlx5a
gene id: 8078:dlx5a
uniprot id: A0A3Q2PMA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8078:clcn3
gene id: 8078:clcn3
uniprot id: A0A3Q2PZQ0
uniprot id: A0A3Q2R0M5
uniprot id: A0A3Q2UPF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8078:psmd1
gene id: 8078:psmd1
uniprot id: A0A3Q2NTW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

8078:gcat
gene id: 8078:gcat
uniprot id: A0A3Q2UAE8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

8078:kcnj15
gene id: 8078:kcnj15
uniprot id: A0A146ZK83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8078:LOC105934261
gene id: 8078:LOC105934261
uniprot id: A0A3Q2UJX1
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:lim2.3
gene id: 8078:lim2.3
uniprot id: A0A3Q2SVB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

8078:sae1
gene id: 8078:sae1
uniprot id: A0A146NTL0
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

8078:prepl
gene id: 8078:prepl
uniprot id: A0A3Q2PWW6
names: Similarity
messages: Belongs to the peptidase S9A family.

8078:gpx7
gene id: 8078:gpx7
uniprot id: A0A146NKF3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

8078:htr2b
gene id: 8078:htr2b
uniprot id: A0A3Q2NU96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

8078:LOC105918891
gene id: 8078:LOC105918891
uniprot id: A0A3Q2QEL4
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

8078:LOC105917273
gene id: 8078:LOC105917273
uniprot id: A0A3Q2NQB3
names: Subcellular Location Annotation
names: Subunit
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome
messages: Secreted

8078:ro60
gene id: 8078:ro60
uniprot id: A0A3Q2UJ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

8078:esrp2
gene id: 8078:esrp2
uniprot id: A0A146WDC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESRP family.
messages: Nucleus

8078:gtf2f2a
gene id: 8078:gtf2f2a
uniprot id: A0A3Q2SVI6
uniprot id: A0A3Q2U2U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

8078:flt4
gene id: 8078:flt4
uniprot id: A0A146QAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Nucleus

8078:sgo1
gene id: 8078:sgo1
uniprot id: A0A3Q2UGF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

8078:mef2cb
gene id: 8078:mef2cb
uniprot id: A0A3Q2QDS6
uniprot id: A0A3Q2QEC3
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105926760
gene id: 8078:LOC105926760
uniprot id: A0A3Q2Q1L0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8078:rogdi
gene id: 8078:rogdi
uniprot id: A0A146ZML2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Perikaryon
messages: Presynapse
messages: synaptic vesicle

8078:raf1a
gene id: 8078:raf1a
uniprot id: A0A146P6L9
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

8078:LOC105936691
gene id: 8078:LOC105936691
uniprot id: A0A3Q2PA70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

8078:mrpl46
gene id: 8078:mrpl46
uniprot id: A0A146S130
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

8078:dgat2
gene id: 8078:dgat2
uniprot id: A0A147A771
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:nutf2
gene id: 8078:nutf2
uniprot id: A0A3Q2U236
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

8078:nup58
gene id: 8078:nup58
uniprot id: A0A3Q2NUW1
names: Subcellular Location Annotation
messages: nuclear pore complex

8078:meox2a
gene id: 8078:meox2a
uniprot id: A0A146ZTD2
names: Subcellular Location Annotation
messages: Nucleus

8078:mocs3
gene id: 8078:mocs3
uniprot id: A0A3Q2T0X0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

8078:LOC105918730
gene id: 8078:LOC105918730
uniprot id: A0A3Q2PGS6
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:hacl1
gene id: 8078:hacl1
uniprot id: A0A3Q2QQC3
names: Similarity
messages: Belongs to the TPP enzyme family.

8078:LOC105917706
gene id: 8078:LOC105917706
uniprot id: A0A3Q2P8U6
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

8078:lrwd1
gene id: 8078:lrwd1
uniprot id: A0A3Q2R0Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

8078:midn
gene id: 8078:midn
uniprot id: A0A3Q2Q187
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105921022
gene id: 8078:LOC105921022
uniprot id: A0A3Q2PS17
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8078:supt6h
gene id: 8078:supt6h
uniprot id: A0A146YDQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

8078:dcp1b
gene id: 8078:dcp1b
uniprot id: A0A3Q2PWC6
names: Similarity
messages: Belongs to the DCP1 family.

8078:lsm6
gene id: 8078:lsm6
uniprot id: A0A3Q2P403
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

8078:LOC105931400
gene id: 8078:LOC105931400
uniprot id: A0A146WB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8078:LOC105923413
gene id: 8078:LOC105923413
uniprot id: A0A3Q2SRN0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8078:LOC105917266
gene id: 8078:LOC105917266
uniprot id: A0A3Q2NQB7
uniprot id: A0A3Q2Q5Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

8078:LOC105927117
gene id: 8078:LOC105927117
uniprot id: A0A3Q2P2W8
names: Subcellular Location Annotation
messages: cytoskeleton

8078:LOC105932046
gene id: 8078:LOC105932046
uniprot id: A0A3Q2PEZ4
names: Similarity
messages: Belongs to the SNF7 family.

8078:slc30a1a
gene id: 8078:slc30a1a
uniprot id: A0A146WBU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8078:baz2a
gene id: 8078:baz2a
uniprot id: A0A3Q2TIN0
names: Similarity
messages: Belongs to the WAL family.

8078:uba6
gene id: 8078:uba6
uniprot id: A0A3Q2T3K2
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

8078:atg13
gene id: 8078:atg13
uniprot id: A0A146XRA0
uniprot id: A0A3Q2R4C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

8078:gatm
gene id: 8078:gatm
uniprot id: A0A146NDI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine.
messages: Homodimer.
messages: Mitochondrion inner membrane

8078:LOC105920621
gene id: 8078:LOC105920621
uniprot id: A0A147B4C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:LOC105936485
gene id: 8078:LOC105936485
uniprot id: A0A146VGW9
uniprot id: A0A3Q2PY55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

8078:sgk2a
gene id: 8078:sgk2a
uniprot id: A0A146P4D4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:si:dkey-246g23.2
gene id: 8078:si:dkey-246g23.2
uniprot id: A0A146RE24
names: Subcellular Location Annotation
messages: Membrane

8078:gngt1
gene id: 8078:gngt1
uniprot id: A0A3Q2PE97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8078:coro1ca
gene id: 8078:coro1ca
uniprot id: A0A3Q2PMZ1
names: Similarity
messages: Belongs to the WD repeat coronin family.

8078:LOC105920544
gene id: 8078:LOC105920544
uniprot id: A0A3Q2UE72
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

8078:slc20a1a
gene id: 8078:slc20a1a
uniprot id: A0A3Q2SPH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

8078:ldb3b
gene id: 8078:ldb3b
uniprot id: A0A146WRU6
uniprot id: A0A3Q2P9F0
names: Subcellular Location Annotation
messages: Z line

8078:sh3pxd2b
gene id: 8078:sh3pxd2b
uniprot id: A0A3Q2PIF8
uniprot id: A0A3Q2PJF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

8078:tha1
gene id: 8078:tha1
uniprot id: A0A3Q2PAC5
names: Similarity
messages: Belongs to the threonine aldolase family.

8078:LOC105927319
gene id: 8078:LOC105927319
uniprot id: A0A3Q2TV08
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

8078:aqp1
gene id: 8078:aqp1
uniprot id: C1ITJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8078:pam16
gene id: 8078:pam16
uniprot id: A0A3Q2QJF0
names: Similarity
messages: Belongs to the TIM16/PAM16 family.

8078:dlgap4b
gene id: 8078:dlgap4b
uniprot id: A0A3Q2QDR4
names: Similarity
messages: Belongs to the SAPAP family.

8078:si:ch211-106h11.3
gene id: 8078:si:ch211-106h11.3
uniprot id: A0A147A4I6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:zgc:165507
gene id: 8078:zgc:165507
uniprot id: B6SCG8
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cytoplasm
messages: Membrane

8078:LOC105931738
gene id: 8078:LOC105931738
uniprot id: A0A3Q2QF34
names: Similarity
messages: Belongs to the intermediate filament family.

8078:ndufaf4
gene id: 8078:ndufaf4
uniprot id: A0A3Q2SWC9
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

8078:crot
gene id: 8078:crot
uniprot id: A0A3Q2TAT0
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8078:LOC105936749
gene id: 8078:LOC105936749
uniprot id: A0A3Q2P605
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:hs6st1a
gene id: 8078:hs6st1a
uniprot id: A0A146QV94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

8078:LOC105936259
gene id: 8078:LOC105936259
uniprot id: A0A3Q2PA83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: cytoskeleton

8078:LOC105922351
gene id: 8078:LOC105922351
uniprot id: A0A147AKD2
names: Similarity
messages: Belongs to the BLOC1S5 family.

8078:chst10
gene id: 8078:chst10
uniprot id: A0A3Q2PZT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:LOC105933145
gene id: 8078:LOC105933145
uniprot id: A0A3Q2PWU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8078:mgst2
gene id: 8078:mgst2
uniprot id: A0A3Q2U577
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

8078:tent5bb
gene id: 8078:tent5bb
uniprot id: A0A3Q2NXY2
names: Similarity
messages: Belongs to the TENT family.

8078:anapc5
gene id: 8078:anapc5
uniprot id: A0A3Q2T4X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

8078:dhrsx
gene id: 8078:dhrsx
uniprot id: A0A3Q2PM39
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:bloc1s3
gene id: 8078:bloc1s3
uniprot id: A0A146NUJ4
uniprot id: A0A3Q2QQR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S3 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).
messages: Cytoplasm

8078:tmem176
gene id: 8078:tmem176
uniprot id: A0A3Q2Q988
names: Similarity
messages: Belongs to the MS4A family.

8078:si:dkey-73n8.3
gene id: 8078:si:dkey-73n8.3
uniprot id: A0A3Q2NUC5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:LOC105935437
gene id: 8078:LOC105935437
uniprot id: A0A3Q2PQ03
names: Similarity
messages: Belongs to the Toll-like receptor family.

8078:rps27.2
gene id: 8078:rps27.2
uniprot id: A0A3Q2Q0K3
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

8078:LOC105916347
gene id: 8078:LOC105916347
uniprot id: A0A3Q2PTE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

8078:dkk3b
gene id: 8078:dkk3b
uniprot id: A0A3Q2TTH0
names: Similarity
messages: Belongs to the dickkopf family.

8078:dazap2
gene id: 8078:dazap2
uniprot id: A0A3Q2P1B5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: nuclear body

8078:nr2c1
gene id: 8078:nr2c1
uniprot id: A0A3Q2QF93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:ido1
gene id: 8078:ido1
uniprot id: A0A146P330
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

8078:cemip2
gene id: 8078:cemip2
uniprot id: A0A146RWW3
names: Similarity
messages: Belongs to the CEMIP family.

8078:mgat5
gene id: 8078:mgat5
uniprot id: A0A3Q2ULY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

8078:polr2eb
gene id: 8078:polr2eb
uniprot id: A0A146NPK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

8078:ypel2b
gene id: 8078:ypel2b
uniprot id: A0A3Q2NS15
names: Similarity
messages: Belongs to the yippee family.

8078:tars1
gene id: 8078:tars1
uniprot id: A0A3Q2U1U3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

8078:pithd1
gene id: 8078:pithd1
uniprot id: A0A3Q2QQJ9
names: Similarity
messages: Belongs to the PITHD1 family.

8078:snupn
gene id: 8078:snupn
uniprot id: A0A3Q2PSB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

8078:LOC105924201
gene id: 8078:LOC105924201
uniprot id: A0A3Q2NUT8
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8078:tcf7l1b
gene id: 8078:tcf7l1b
uniprot id: A0A3Q2TPI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8078:ddx1
gene id: 8078:ddx1
uniprot id: A0A3Q2P4V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule

8078:rps6ka2
gene id: 8078:rps6ka2
uniprot id: A0A3Q2PYJ4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8078:foxd3
gene id: 8078:foxd3
uniprot id: A0A3Q2Q4L6
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105934588
gene id: 8078:LOC105934588
uniprot id: A0A146VT27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8078:pigm
gene id: 8078:pigm
uniprot id: A0A3Q2PS46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

8078:rnft1
gene id: 8078:rnft1
uniprot id: A0A3Q2PLP9
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105940388
gene id: 8078:LOC105940388
uniprot id: A0A147B0C3
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

8078:LOC105930351
gene id: 8078:LOC105930351
uniprot id: A0A147A3N4
names: Similarity
messages: Belongs to the FAM124 family.

8078:fam168b
gene id: 8078:fam168b
uniprot id: A0A3Q2TP94
names: Similarity
messages: Belongs to the FAM168 family.

8078:LOC105920253
gene id: 8078:LOC105920253
uniprot id: A0A3Q2Q959
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105936528
gene id: 8078:LOC105936528
uniprot id: A0A3Q2ULH1
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:dyrk3
gene id: 8078:dyrk3
uniprot id: A0A3Q2TSA6
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8078:arl5c
gene id: 8078:arl5c
uniprot id: A0A3Q2PGS8
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8078:atf4a
gene id: 8078:atf4a
uniprot id: A0A3Q2QIL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

8078:pxmp2
gene id: 8078:pxmp2
uniprot id: A0A146N2Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

8078:ap4s1
gene id: 8078:ap4s1
uniprot id: A0A3Q2QBB4
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

8078:hmox1a
gene id: 8078:hmox1a
uniprot id: A0A3Q2QJC7
names: Similarity
messages: Belongs to the heme oxygenase family.

8078:LOC105939973
gene id: 8078:LOC105939973
uniprot id: A0A3Q2QRV1
names: Subcellular Location Annotation
messages: sarcolemma

8078:LOC105939441
gene id: 8078:LOC105939441
uniprot id: A0A3Q2QSR7
names: Subcellular Location Annotation
messages: Nucleus

8078:pdgfab
gene id: 8078:pdgfab
uniprot id: A0A146NDR9
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8078:ehf
gene id: 8078:ehf
uniprot id: A0A147AU95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:tvp23b
gene id: 8078:tvp23b
uniprot id: A0A3Q2QL00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

8078:pskh1
gene id: 8078:pskh1
uniprot id: A0A3Q2T7A5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:lingo1a
gene id: 8078:lingo1a
uniprot id: A0A3Q2PGC9
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105921604
gene id: 8078:LOC105921604
uniprot id: A0A3Q2Q2H3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8078:mcoln1a
gene id: 8078:mcoln1a
uniprot id: A0A3Q2Q7Z9
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8078:poc1bl
gene id: 8078:poc1bl
uniprot id: A0A3Q2NME2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8078:LOC105937985
gene id: 8078:LOC105937985
uniprot id: A0A3Q2P5G3
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8078:antxr1a
gene id: 8078:antxr1a
uniprot id: A0A147A9N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

8078:ddx5
gene id: 8078:ddx5
uniprot id: A0A146WGQ1
names: Similarity
messages: Belongs to the DEAD box helicase family.

8078:tet2
gene id: 8078:tet2
uniprot id: A0A3Q2R3G8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

8078:gatc
gene id: 8078:gatc
uniprot id: A0A147A9F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

8078:enoph1
gene id: 8078:enoph1
uniprot id: A0A146TUE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

8078:paf1
gene id: 8078:paf1
uniprot id: A0A146PAW1
names: Similarity
messages: Belongs to the PAF1 family.

8078:LOC105931565
gene id: 8078:LOC105931565
uniprot id: A0A3Q2QM99
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8078:serinc2
gene id: 8078:serinc2
uniprot id: A0A3Q2NYX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

8078:acsl3a
gene id: 8078:acsl3a
uniprot id: A0A147A9R6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8078:unc45b
gene id: 8078:unc45b
uniprot id: A0A3Q2QC10
names: Subcellular Location Annotation
messages: A band
messages: Z line
messages: perinuclear region

8078:cul4b
gene id: 8078:cul4b
uniprot id: A0A3Q2QV53
names: Similarity
messages: Belongs to the cullin family.

8078:rbm5
gene id: 8078:rbm5
uniprot id: A0A146XXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

8078:atp6v0d1
gene id: 8078:atp6v0d1
uniprot id: A0A3Q2Q2C7
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

8078:aldh1l1
gene id: 8078:aldh1l1
uniprot id: A0A3Q2QVF3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

8078:ubac2
gene id: 8078:ubac2
uniprot id: A0A3Q2R0U9
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105939096
gene id: 8078:LOC105939096
uniprot id: A0A3Q2QCJ5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8078:cysltr1
gene id: 8078:cysltr1
uniprot id: A0A3Q2QQY5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:cpb2
gene id: 8078:cpb2
uniprot id: A0A3Q2PZM4
names: Similarity
messages: Belongs to the peptidase M14 family.

8078:ankrd34c
gene id: 8078:ankrd34c
uniprot id: A0A3Q2NRY9
names: Similarity
messages: Belongs to the ANKRD34 family.

8078:zgc:194282
gene id: 8078:zgc:194282
uniprot id: A0A146YRK3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8078:abl1
gene id: 8078:abl1
uniprot id: A0A147A1P8
uniprot id: A0A3Q2QY23
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8078:LOC105929329
gene id: 8078:LOC105929329
uniprot id: A0A3Q2SP60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8078:gdpd5b
gene id: 8078:gdpd5b
uniprot id: A0A3Q2NNI9
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8078:hsd11b2
gene id: 8078:hsd11b2
uniprot id: A0A147ARD5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:LOC105938173
gene id: 8078:LOC105938173
uniprot id: A0A146V6X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8078:slc15a2
gene id: 8078:slc15a2
uniprot id: A0A147A3M5
names: Similarity
names: Subunit
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.

8078:si:dkey-33m11.6
gene id: 8078:si:dkey-33m11.6
uniprot id: A0A3Q2QBR0
names: Similarity
messages: Belongs to the CAMK2N family.

8078:prss1
gene id: 8078:prss1
uniprot id: A0A3Q2QBJ8
names: Subcellular Location Annotation
messages: extracellular space

8078:sec61a1
gene id: 8078:sec61a1
uniprot id: A0A146N3P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.
messages: Membrane
messages: Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins (By similarity). Plays a role in pronephric kidney tubule development.

8078:LOC105928405
gene id: 8078:LOC105928405
uniprot id: A0A3Q2NYG6
uniprot id: A0A3Q2QCU7
names: Subcellular Location Annotation
messages: extracellular space

8078:kmt5b
gene id: 8078:kmt5b
uniprot id: A0A3Q2QY91
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8078:LOC105918180
gene id: 8078:LOC105918180
uniprot id: A0A3Q2PK12
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

8078:med1
gene id: 8078:med1
uniprot id: A0A3Q2PMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8078:rmi1
gene id: 8078:rmi1
uniprot id: A0A3Q2Q188
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RMI1 family.
messages: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
messages: Nucleus

8078:nipsnap3a
gene id: 8078:nipsnap3a
uniprot id: A0A3Q2QD48
names: Similarity
messages: Belongs to the NipSnap family.

8078:rbp5
gene id: 8078:rbp5
uniprot id: A0A3Q2QP80
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8078:LOC105915650
gene id: 8078:LOC105915650
uniprot id: A0A146QX72
names: Subcellular Location Annotation
messages: Secreted

8078:plin3
gene id: 8078:plin3
uniprot id: A0A3Q2SPL5
names: Similarity
messages: Belongs to the perilipin family.

8078:capn9
gene id: 8078:capn9
uniprot id: A0A147A103
names: Similarity
messages: Belongs to the peptidase C2 family.

8078:sema3gb
gene id: 8078:sema3gb
uniprot id: A0A3Q2R0V0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:acer2
gene id: 8078:acer2
uniprot id: A0A3Q2PZH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

8078:LOC105926199
gene id: 8078:LOC105926199
uniprot id: A0A3Q2TNP8
names: Function
names: Similarity
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

8078:hs3st4
gene id: 8078:hs3st4
uniprot id: A0A3Q2R0Q2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8078:scn3b
gene id: 8078:scn3b
uniprot id: A0A3Q2P0L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

8078:kirrel3l
gene id: 8078:kirrel3l
uniprot id: A0A3Q2QM36
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105929694
gene id: 8078:LOC105929694
uniprot id: A0A3Q2Q086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium axoneme
messages: kinetochore
messages: spindle

8078:edem1
gene id: 8078:edem1
uniprot id: A0A3Q2QYU2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8078:far1
gene id: 8078:far1
uniprot id: A0A146WLG9
uniprot id: A0A3Q2UPV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

8078:gstcd
gene id: 8078:gstcd
uniprot id: A0A3Q2UPV4
names: Similarity
messages: Belongs to the GSTCD family.

8078:LOC105938942
gene id: 8078:LOC105938942
uniprot id: A0A146ZL03
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:LOC105935093
gene id: 8078:LOC105935093
uniprot id: A0A146PAH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

8078:sarm1
gene id: 8078:sarm1
uniprot id: A0A3Q2PYI2
names: Similarity
messages: Belongs to the SARM1 family.

8078:rars1
gene id: 8078:rars1
uniprot id: A0A3Q2UJH5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8078:cdc42ep4a
gene id: 8078:cdc42ep4a
uniprot id: A0A3Q2UEL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8078:hcn4
gene id: 8078:hcn4
uniprot id: A0A3Q2UQH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

8078:apoc2
gene id: 8078:apoc2
uniprot id: A0A3Q2PD28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C2 family.
messages: Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.
messages: Secreted

8078:LOC105927699
gene id: 8078:LOC105927699
uniprot id: A0A3Q2U646
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

8078:sf3a1
gene id: 8078:sf3a1
uniprot id: A0A3Q2QIN2
names: Subcellular Location Annotation
messages: Nucleus

8078:atf7a
gene id: 8078:atf7a
uniprot id: A0A3Q2QA88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

8078:dhx8
gene id: 8078:dhx8
uniprot id: A0A3Q2T808
names: Subcellular Location Annotation
messages: Nucleus

8078:xk
gene id: 8078:xk
uniprot id: A0A3Q2TBZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8078:noc3l
gene id: 8078:noc3l
uniprot id: A0A3Q2Q837
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: nucleolus

8078:tceanc2
gene id: 8078:tceanc2
uniprot id: A0A147A1I0
names: Subcellular Location Annotation
messages: Nucleus

8078:emp1
gene id: 8078:emp1
uniprot id: A0A3Q2QJN8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:adgra3
gene id: 8078:adgra3
uniprot id: A0A3Q2TTJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

8078:spon1a
gene id: 8078:spon1a
uniprot id: A0A3Q2PZP9
names: Subcellular Location Annotation
messages: extracellular matrix

8078:LOC105932267
gene id: 8078:LOC105932267
uniprot id: A0A3Q2QA56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8078:LOC105916411
gene id: 8078:LOC105916411
uniprot id: A0A3Q2QP48
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:slc52a2
gene id: 8078:slc52a2
uniprot id: A0A147AX30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

8078:cers2a
gene id: 8078:cers2a
uniprot id: A0A3Q2PF15
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8078:LOC105932851
gene id: 8078:LOC105932851
uniprot id: A0A146RR34
names: Subcellular Location Annotation
messages: Nucleus

8078:tpi1b
gene id: 8078:tpi1b
uniprot id: A0A3Q2PDL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

8078:cdkn1ba
gene id: 8078:cdkn1ba
uniprot id: A0A3Q2QFL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDI family.
messages: Cytoplasm
messages: Endosome
messages: Nucleus

8078:si:ch211-45c16.2
gene id: 8078:si:ch211-45c16.2
uniprot id: A0A3Q2P5I2
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8078:b4galt3
gene id: 8078:b4galt3
uniprot id: A0A3Q2R031
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8078:palm1b
gene id: 8078:palm1b
uniprot id: A0A3Q2PV08
names: Similarity
messages: Belongs to the paralemmin family.

8078:LOC105930298
gene id: 8078:LOC105930298
uniprot id: A0A146P6Q1
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

8078:LOC105918296
gene id: 8078:LOC105918296
uniprot id: A0A3Q2P3K0
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

8078:ngrn
gene id: 8078:ngrn
uniprot id: A0A3Q2SVF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

8078:LOC105936529
gene id: 8078:LOC105936529
uniprot id: A0A3Q2T2A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

8078:LOC105918667
gene id: 8078:LOC105918667
uniprot id: A0A3Q2QQX9
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

8078:ehd3
gene id: 8078:ehd3
uniprot id: A0A146P5R2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

8078:bmp7b
gene id: 8078:bmp7b
uniprot id: A0A3Q2NT54
names: Similarity
messages: Belongs to the TGF-beta family.

8078:utp18
gene id: 8078:utp18
uniprot id: A0A3Q2PW26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

8078:plac8l1
gene id: 8078:plac8l1
uniprot id: A0A3Q2T493
names: Similarity
messages: Belongs to the cornifelin family.

8078:flt3
gene id: 8078:flt3
uniprot id: A0A3Q2PN96
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:LOC105916911
gene id: 8078:LOC105916911
uniprot id: A0A3Q2TJQ4
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8078:fam98b
gene id: 8078:fam98b
uniprot id: A0A146X9D7
names: Similarity
messages: Belongs to the FAM98 family.

8078:LOC105931473
gene id: 8078:LOC105931473
uniprot id: A0A3Q2P8B3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8078:LOC105923754
gene id: 8078:LOC105923754
uniprot id: A0A3Q2TD93
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8078:pnrc2
gene id: 8078:pnrc2
uniprot id: A0A3Q2PTN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNRC family. PNRC2 subfamily.
messages: Nucleus
messages: P-body

8078:traf6
gene id: 8078:traf6
uniprot id: A0A146P7D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

8078:LOC105930409
gene id: 8078:LOC105930409
uniprot id: A0A146P5A4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

8078:psmg1
gene id: 8078:psmg1
uniprot id: A0A3Q2UNV8
names: Similarity
messages: Belongs to the PSMG1 family.

8078:lgsn
gene id: 8078:lgsn
uniprot id: A0A3Q2TZR9
names: Similarity
messages: Belongs to the glutamine synthetase family.

8078:LOC105929587
gene id: 8078:LOC105929587
uniprot id: A0A147A458
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8078:tcp11l2
gene id: 8078:tcp11l2
uniprot id: A0A3Q2QB39
names: Similarity
messages: Belongs to the TCP11 family.

8078:LOC105932515
gene id: 8078:LOC105932515
uniprot id: A0A3Q2PXI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

8078:guf1
gene id: 8078:guf1
uniprot id: A0A3Q2TGL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

8078:bmpr1ba
gene id: 8078:bmpr1ba
uniprot id: A0A3Q2PME0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8078:fshr
gene id: 8078:fshr
uniprot id: A3KEZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

8078:LOC105931479
gene id: 8078:LOC105931479
uniprot id: A0A146QCA9
uniprot id: A0A3Q2PHP3
names: Subcellular Location Annotation
messages: Nucleus

8078:fez1
gene id: 8078:fez1
uniprot id: A0A3Q2NVS2
names: Similarity
messages: Belongs to the zygin family.

8078:degs2
gene id: 8078:degs2
uniprot id: A0A3Q2P3D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:LOC105931213
gene id: 8078:LOC105931213
uniprot id: A0A3Q2Q6X5
names: Subcellular Location Annotation
messages: Nucleus

8078:si:ch73-174h16.4
gene id: 8078:si:ch73-174h16.4
uniprot id: A0A3Q2P760
names: Subcellular Location Annotation
messages: Cytoplasm

8078:nr1d2b
gene id: 8078:nr1d2b
uniprot id: A0A3Q2PUC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:idh2
gene id: 8078:idh2
uniprot id: A0A146W373
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

8078:xkr9
gene id: 8078:xkr9
uniprot id: A0A3Q2PT24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8078:LOC105938585
gene id: 8078:LOC105938585
uniprot id: A0A3Q2U6D6
names: Similarity
messages: Belongs to the TEX28 family.

8078:hmces
gene id: 8078:hmces
uniprot id: A0A3Q2QAU2
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

8078:eif2b1
gene id: 8078:eif2b1
uniprot id: A0A146P4E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

8078:LOC105935587
gene id: 8078:LOC105935587
uniprot id: A0A146VMM0
names: Similarity
messages: Belongs to the BANP/SMAR1 family.

8078:snx20
gene id: 8078:snx20
uniprot id: A0A3Q2QXD5
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

8078:ptges3l
gene id: 8078:ptges3l
uniprot id: A0A3Q2PW92
names: Similarity
messages: Belongs to the p23/wos2 family.

8078:LOC105935254
gene id: 8078:LOC105935254
uniprot id: A0A3Q2P218
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:dnajb14
gene id: 8078:dnajb14
uniprot id: A0A3Q2P198
names: Subcellular Location Annotation
messages: Membrane

8078:ldb2a
gene id: 8078:ldb2a
uniprot id: A0A146P5L1
names: Similarity
messages: Belongs to the LDB family.

8078:gins3
gene id: 8078:gins3
uniprot id: A0A3Q2PZ89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

8078:LOC105936520
gene id: 8078:LOC105936520
uniprot id: A0A146VFR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

8078:eomesa
gene id: 8078:eomesa
uniprot id: A0A3Q2QTB2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:LOC105925462
gene id: 8078:LOC105925462
uniprot id: A0A3Q2NZY8
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105935774
gene id: 8078:LOC105935774
uniprot id: A0A3Q2TYQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8078:hs6st2
gene id: 8078:hs6st2
uniprot id: A0A147ACN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

8078:yes1
gene id: 8078:yes1
uniprot id: A0A3Q2PUJ4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8078:pepd
gene id: 8078:pepd
uniprot id: A0A3Q2P8Z3
names: Similarity
messages: Belongs to the peptidase M24B family.

8078:dynlt1
gene id: 8078:dynlt1
uniprot id: A0A146WLG7
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8078:skia
gene id: 8078:skia
uniprot id: A0A3Q2PI48
names: Similarity
messages: Belongs to the SKI family.

8078:fzd3a
gene id: 8078:fzd3a
uniprot id: A0A146ZQP7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:si:ch73-352p4.8
gene id: 8078:si:ch73-352p4.8
uniprot id: A0A3Q2TST7
names: Subcellular Location Annotation
messages: Membrane

8078:wdr32
gene id: 8078:wdr32
uniprot id: A0A3Q2PBP9
names: Function
names: Similarity
messages: Belongs to the WD repeat DCAF10 family.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

8078:sap18
gene id: 8078:sap18
uniprot id: A0A146VM82
names: Function
names: Similarity
messages: Belongs to the SAP18 family.
messages: Involved in the tethering of the SIN3 complex to core histone proteins.

8078:clstn3
gene id: 8078:clstn3
uniprot id: A0A146MYP5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

8078:nop56
gene id: 8078:nop56
uniprot id: A0A3Q2NTJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

8078:camk2d1
gene id: 8078:camk2d1
uniprot id: A0A3Q2NY80
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8078:LOC105935181
gene id: 8078:LOC105935181
uniprot id: A0A3Q2P2Z7
names: Subcellular Location Annotation
messages: extracellular space

8078:cxcr3.2
gene id: 8078:cxcr3.2
uniprot id: A0A146ZKH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8078:fam20a
gene id: 8078:fam20a
uniprot id: A0A3Q2P1W6
names: Similarity
messages: Belongs to the FAM20 family.

8078:laptm4b
gene id: 8078:laptm4b
uniprot id: A0A147B2V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

8078:LOC105938985
gene id: 8078:LOC105938985
uniprot id: A0A3Q2PBV3
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105917250
gene id: 8078:LOC105917250
uniprot id: A0A3Q2NWC0
uniprot id: A0A3Q2NWE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Midbody
messages: Nucleus
messages: kinetochore
messages: spindle

8078:gtf2h4
gene id: 8078:gtf2h4
uniprot id: A0A3Q2R412
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

8078:LOC105918994
gene id: 8078:LOC105918994
uniprot id: A0A146Y8A6
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

8078:anxa3a
gene id: 8078:anxa3a
uniprot id: A0A3Q2T8H4
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8078:fabp6
gene id: 8078:fabp6
uniprot id: A0A3Q2UPY5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8078:trak2
gene id: 8078:trak2
uniprot id: A0A3Q2QDT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

8078:prodhb
gene id: 8078:prodhb
uniprot id: A0A3Q2NTN9
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

8078:slc25a46
gene id: 8078:slc25a46
uniprot id: A0A3Q2SWT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

8078:lmln
gene id: 8078:lmln
uniprot id: A0A3Q2NPB7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

8078:si:dkey-10o6.2
gene id: 8078:si:dkey-10o6.2
uniprot id: A0A3Q2PVX3
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

8078:senp2
gene id: 8078:senp2
uniprot id: A0A3Q2P6X5
names: Similarity
messages: Belongs to the peptidase C48 family.

8078:LOC105917538
gene id: 8078:LOC105917538
uniprot id: A0A3Q2PLB4
names: Similarity
messages: Belongs to the TMEM106 family.

8078:LOC105928689
gene id: 8078:LOC105928689
uniprot id: A0A3Q2NS71
names: Similarity
messages: Belongs to the requiem/DPF family.

8078:abcb6a
gene id: 8078:abcb6a
uniprot id: A0A3Q2PYW5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: extracellular exosome
messages: multivesicular body membrane

8078:rftn1a
gene id: 8078:rftn1a
uniprot id: A0A146ZUY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

8078:emsy
gene id: 8078:emsy
uniprot id: A0A3Q2R2G1
names: Subcellular Location Annotation
messages: Nucleus

8078:hnf4g
gene id: 8078:hnf4g
uniprot id: A0A3Q2U0V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

8078:ikbkb
gene id: 8078:ikbkb
uniprot id: A0A3Q2P2L2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8078:efna3b
gene id: 8078:efna3b
uniprot id: A0A147A6D6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:adss1
gene id: 8078:adss1
uniprot id: A0A147AXK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

8078:mych
gene id: 8078:mych
uniprot id: A0A3Q2NTN0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

8078:si:ch211-107o10.3
gene id: 8078:si:ch211-107o10.3
uniprot id: A0A3Q2QMW8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:casp3a
gene id: 8078:casp3a
uniprot id: A0A3Q2QJ73
names: Similarity
messages: Belongs to the peptidase C14A family.

8078:nppc
gene id: 8078:nppc
uniprot id: A0A146ZX80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

8078:mtmr6
gene id: 8078:mtmr6
uniprot id: A0A3Q2STG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

8078:supt16h
gene id: 8078:supt16h
uniprot id: A0A3Q2UNR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

8078:elf1
gene id: 8078:elf1
uniprot id: A0A3Q2TJC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:si:dkey-69o16.5
gene id: 8078:si:dkey-69o16.5
uniprot id: A0A3Q2TXF3
names: Similarity
messages: Belongs to the peptidase S51 family.

8078:epha6
gene id: 8078:epha6
uniprot id: A0A3Q2P7I5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:slc39a1
gene id: 8078:slc39a1
uniprot id: A0A146P788
names: Subcellular Location Annotation
messages: Membrane

8078:slc35b2
gene id: 8078:slc35b2
uniprot id: A0A3Q2NU73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

8078:slc35b4
gene id: 8078:slc35b4
uniprot id: A0A3Q2P2M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

8078:gmds
gene id: 8078:gmds
uniprot id: A0A3Q2QF03
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

8078:dok1b
gene id: 8078:dok1b
uniprot id: A0A3Q2NYU4
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

8078:acadvl
gene id: 8078:acadvl
uniprot id: A0A3Q2SPB6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8078:rps3
gene id: 8078:rps3
uniprot id: A0A3Q2R1J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: nucleolus
messages: spindle

8078:nppa
gene id: 8078:nppa
uniprot id: Q805E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

8078:LOC105915764
gene id: 8078:LOC105915764
uniprot id: A0A3Q2Q2C0
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8078:hip1rb
gene id: 8078:hip1rb
uniprot id: A0A3Q2PSL6
names: Similarity
messages: Belongs to the SLA2 family.

8078:LOC105931877
gene id: 8078:LOC105931877
uniprot id: A0A146ZZN2
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8078:sar1b
gene id: 8078:sar1b
uniprot id: A0A3Q2QXW3
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

8078:phgdh
gene id: 8078:phgdh
uniprot id: A0A146ZXD0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

8078:rps5
gene id: 8078:rps5
uniprot id: A0A3Q2T2D2
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

8078:LOC105932615
gene id: 8078:LOC105932615
uniprot id: A0A146ZYD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8078:cdca7b
gene id: 8078:cdca7b
uniprot id: A0A3Q2QMK7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8078:smpd2b
gene id: 8078:smpd2b
uniprot id: A0A3Q2PS60
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

8078:LOC105917343
gene id: 8078:LOC105917343
uniprot id: A0A3Q2R179
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8078:LOC105919737
gene id: 8078:LOC105919737
uniprot id: A0A3Q2PZ67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

8078:dbr1
gene id: 8078:dbr1
uniprot id: A0A146P7A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

8078:LOC105916249
gene id: 8078:LOC105916249
uniprot id: A0A147AZE1
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:slc5a6a
gene id: 8078:slc5a6a
uniprot id: A0A3Q2PD07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8078:b3gnt5b
gene id: 8078:b3gnt5b
uniprot id: A0A3Q2TGE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:dhx29
gene id: 8078:dhx29
uniprot id: A0A146NK48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC).

8078:ccm2
gene id: 8078:ccm2
uniprot id: A0A3Q2PVM5
names: Similarity
messages: Belongs to the CCM2 family.

8078:vps4a
gene id: 8078:vps4a
uniprot id: A0A146MLZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8078:mmgt1
gene id: 8078:mmgt1
uniprot id: A0A146NR12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

8078:LOC105935727
gene id: 8078:LOC105935727
uniprot id: A0A3Q2NT13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

8078:fam214a
gene id: 8078:fam214a
uniprot id: A0A3Q2QQ47
names: Similarity
messages: Belongs to the FAM214 family.

8078:fscn1a
gene id: 8078:fscn1a
uniprot id: A0A3Q2PBY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

8078:LOC105935349
gene id: 8078:LOC105935349
uniprot id: A0A3Q2TIT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

8078:fam167ab
gene id: 8078:fam167ab
uniprot id: A0A3Q2PVD9
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

8078:hoxa13a
gene id: 8078:hoxa13a
uniprot id: A0A3Q2PH48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8078:gpn2
gene id: 8078:gpn2
uniprot id: A0A3Q2PKE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

8078:mief1
gene id: 8078:mief1
uniprot id: A0A3Q2NZ94
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8078:KEG95 p09
gene id: 8078:KEG95_p09
uniprot id: B7U7V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase protein 8 family.
messages: Membrane
messages: Mitochondrion membrane

8078:setd6
gene id: 8078:setd6
uniprot id: A0A3Q2TPJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: Protein-lysine N-methyltransferase.

8078:csrnp1b
gene id: 8078:csrnp1b
uniprot id: A0A3Q2QMZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8078:boka
gene id: 8078:boka
uniprot id: A0A147ACI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

8078:LOC105935619
gene id: 8078:LOC105935619
uniprot id: A0A146VL03
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105930728
gene id: 8078:LOC105930728
uniprot id: A0A146SHG3
names: Subcellular Location Annotation
messages: Membrane

8078:sv2ca
gene id: 8078:sv2ca
uniprot id: A0A3Q2U4X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

8078:si:ch211-283g2.1
gene id: 8078:si:ch211-283g2.1
uniprot id: A0A3Q2PDA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8078:fuca2
gene id: 8078:fuca2
uniprot id: A0A3Q2NTJ2
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

8078:mmachc
gene id: 8078:mmachc
uniprot id: A0A3Q2Q5Q1
names: Similarity
messages: Belongs to the MMACHC family.

8078:LOC105920584
gene id: 8078:LOC105920584
uniprot id: A0A146S0A9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:LOC105938908
gene id: 8078:LOC105938908
uniprot id: A0A3Q2QQR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8078:cart2
gene id: 8078:cart2
uniprot id: A0A3Q2TJY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8078:vps4b
gene id: 8078:vps4b
uniprot id: A0A3Q2QSG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Late endosome membrane

8078:cldnf
gene id: 8078:cldnf
uniprot id: A0A3Q2Q034
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8078:arf2a
gene id: 8078:arf2a
uniprot id: A0A146YXG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8078:creb3l2
gene id: 8078:creb3l2
uniprot id: A0A3Q2NSL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family. ATF subfamily.
messages: Binds DNA as a dimer.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8078:mars1
gene id: 8078:mars1
uniprot id: A0A3Q2PPD1
uniprot id: A0A3Q2PPR0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8078:LOC105938610
gene id: 8078:LOC105938610
uniprot id: A0A3Q2QHW7
names: Subcellular Location Annotation
messages: Membrane

8078:ormdl3
gene id: 8078:ormdl3
uniprot id: A0A3Q2P0N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

8078:htra1a
gene id: 8078:htra1a
uniprot id: A0A3Q2TPG9
names: Similarity
messages: Belongs to the peptidase S1C family.

8078:rbfox2
gene id: 8078:rbfox2
uniprot id: A0A3Q2UAM2
names: Subcellular Location Annotation
messages: Nucleus

8078:ppie
gene id: 8078:ppie
uniprot id: A0A3Q2SZT5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.

8078:phyhiplb
gene id: 8078:phyhiplb
uniprot id: A0A3Q2Q2E6
names: Similarity
messages: Belongs to the PHYHIP family.

8078:ppp1r3b
gene id: 8078:ppp1r3b
uniprot id: A0A3Q2QCP3
names: Subunit
messages: Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.

8078:c12h12orf43
gene id: 8078:c12h12orf43
uniprot id: A0A3Q2Q3C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

8078:mterf4
gene id: 8078:mterf4
uniprot id: A0A3Q2TNX5
names: Similarity
messages: Belongs to the mTERF family.

8078:ndnf
gene id: 8078:ndnf
uniprot id: A0A3Q2PFB8
names: Subcellular Location Annotation
messages: Secreted

8078:ttyh2
gene id: 8078:ttyh2
uniprot id: A0A3Q2P663
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8078:ppp2cab
gene id: 8078:ppp2cab
uniprot id: A0A3Q2PW32
names: Similarity
messages: Belongs to the PPP phosphatase family.

8078:ppp6r3
gene id: 8078:ppp6r3
uniprot id: A0A3Q2U9C4
names: Similarity
messages: Belongs to the SAPS family.

8078:ggnbp2
gene id: 8078:ggnbp2
uniprot id: A0A3Q2PDG8
names: Function
messages: May be involved in spermatogenesis.

8078:usp10
gene id: 8078:usp10
uniprot id: A0A3Q2TAQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP10 subfamily.
messages: Cytoplasm
messages: Nucleus

8078:sgcb
gene id: 8078:sgcb
uniprot id: A0A3Q2QYT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The association between SGCB and SGCG is particularly strong while SGCA is loosely associated with the other sarcoglycans.
messages: cytoskeleton
messages: sarcolemma

8078:LOC105930792
gene id: 8078:LOC105930792
uniprot id: A0A3Q2T828
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

8078:sumo3b
gene id: 8078:sumo3b
uniprot id: A0A3Q2T080
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8078:LOC105928830
gene id: 8078:LOC105928830
uniprot id: A0A3Q2NMW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8078:clvs2
gene id: 8078:clvs2
uniprot id: A0A3Q2Q408
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

8078:grinaa
gene id: 8078:grinaa
uniprot id: A0A146P5J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8078:cnot8
gene id: 8078:cnot8
uniprot id: A0A3Q2QT19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

8078:LOC105918369
gene id: 8078:LOC105918369
uniprot id: A0A3Q2P0K1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8078:zgc:86896
gene id: 8078:zgc:86896
uniprot id: A0A3Q2P812
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.

8078:ablim3
gene id: 8078:ablim3
uniprot id: A0A3Q2PBX1
uniprot id: A0A3Q2QJY4
names: Subcellular Location Annotation
messages: Cytoplasm

8078:nr3c2
gene id: 8078:nr3c2
uniprot id: A0A147AAU5
names: Subcellular Location Annotation
messages: Nucleus

8078:f9a
gene id: 8078:f9a
uniprot id: A0A3Q2PNQ9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8078:LOC105936904
gene id: 8078:LOC105936904
uniprot id: A0A3Q2Q7K7
names: Similarity
messages: Belongs to the gamma-glutamyltransferase family.

8078:sgk1
gene id: 8078:sgk1
uniprot id: A0A146WFF5
uniprot id: A0A3Q2P2L1
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:zgc:91944
gene id: 8078:zgc:91944
uniprot id: A0A3Q2PPD2
uniprot id: A0A3Q2PQY7
names: Subcellular Location Annotation
messages: Nucleus

8078:peds1
gene id: 8078:peds1
uniprot id: A0A3Q2NZ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

8078:slc25a55a
gene id: 8078:slc25a55a
uniprot id: A0A3Q2QUJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:LOC105916431
gene id: 8078:LOC105916431
uniprot id: A0A3Q2QQV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

8078:LOC105934125
gene id: 8078:LOC105934125
uniprot id: Q587L0
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105919725
gene id: 8078:LOC105919725
uniprot id: A0A147AR68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

8078:LOC105937599
gene id: 8078:LOC105937599
uniprot id: A0A3Q2PZU1
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

8078:wee2
gene id: 8078:wee2
uniprot id: A0A3Q2SXF3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

8078:prkab1a
gene id: 8078:prkab1a
uniprot id: A0A3Q2Q9V4
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

8078:thbs1b
gene id: 8078:thbs1b
uniprot id: A0A146P5Y0
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:si:ch1073-416d2.3
gene id: 8078:si:ch1073-416d2.3
uniprot id: A0A3Q2QK90
names: Similarity
messages: Belongs to the serpin family.

8078:sox1b
gene id: 8078:sox1b
uniprot id: A0A3Q2R1M3
names: Subcellular Location Annotation
messages: Nucleus

8078:ttc36
gene id: 8078:ttc36
uniprot id: A0A3Q2PZA9
names: Similarity
messages: Belongs to the TTC36 family.

8078:plxna1b
gene id: 8078:plxna1b
uniprot id: A0A3Q2T028
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:prdx5
gene id: 8078:prdx5
uniprot id: A0A3Q2NZ09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Peroxisome matrix
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

8078:LOC105928142
gene id: 8078:LOC105928142
uniprot id: A0A3Q2UEU2
names: Similarity
messages: Belongs to the yippee family.

8078:tyr
gene id: 8078:tyr
uniprot id: A0A147AH67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

8078:lmod2b
gene id: 8078:lmod2b
uniprot id: A0A3Q2ULF4
names: Subcellular Location Annotation
messages: cytoskeleton

8078:foxl2l
gene id: 8078:foxl2l
uniprot id: A0A3Q2P5Y3
names: Subcellular Location Annotation
messages: Nucleus

8078:tbx5a
gene id: 8078:tbx5a
uniprot id: A0A3Q2TJZ7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:tmprss13a
gene id: 8078:tmprss13a
uniprot id: A0A3Q2QSH2
names: Subcellular Location Annotation
messages: extracellular space

8078:cav2
gene id: 8078:cav2
uniprot id: A0A3Q2U9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

8078:LOC105926458
gene id: 8078:LOC105926458
uniprot id: A0A3Q2UCJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: spindle pole

8078:ssbp3b
gene id: 8078:ssbp3b
uniprot id: A0A146MKC8
uniprot id: A0A3Q2NPF1
names: Subcellular Location Annotation
messages: Nucleus

8078:slc25a26
gene id: 8078:slc25a26
uniprot id: A0A3Q2Q9I7
uniprot id: A0A3Q2SUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:gosr1
gene id: 8078:gosr1
uniprot id: A0A3Q2R1G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

8078:gemin2
gene id: 8078:gemin2
uniprot id: A0A3Q2PY73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

8078:slc16a5a
gene id: 8078:slc16a5a
uniprot id: A0A3Q2NX71
names: Subcellular Location Annotation
messages: Membrane

8078:sepsecs
gene id: 8078:sepsecs
uniprot id: A0A3Q2Q230
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

8078:med13a
gene id: 8078:med13a
uniprot id: A0A146WSW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8078:npy2r
gene id: 8078:npy2r
uniprot id: A0A3Q2UIQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:cyfip1
gene id: 8078:cyfip1
uniprot id: A0A3Q2T6S7
names: Similarity
messages: Belongs to the CYFIP family.

8078:foxg1c
gene id: 8078:foxg1c
uniprot id: A0A3Q2PMK4
names: Subcellular Location Annotation
messages: Nucleus

8078:ywhag2
gene id: 8078:ywhag2
uniprot id: A0A3Q2PIG3
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8078:rtn1a
gene id: 8078:rtn1a
uniprot id: A0A3Q2T1M9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:tfec
gene id: 8078:tfec
uniprot id: A0A3Q2TW59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8078:onecut1
gene id: 8078:onecut1
uniprot id: A0A3Q2QP95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8078:xkr5a
gene id: 8078:xkr5a
uniprot id: A0A3Q2TV41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8078:LOC105927130
gene id: 8078:LOC105927130
uniprot id: A0A146Z5B9
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8078:polr2g
gene id: 8078:polr2g
uniprot id: A0A3Q2NST5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: Nucleus

8078:sox9a
gene id: 8078:sox9a
uniprot id: A0A3Q2PS99
names: Subcellular Location Annotation
messages: Nucleus

8078:mgrn1b
gene id: 8078:mgrn1b
uniprot id: A0A3Q2Q6E0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

8078:ackr4b
gene id: 8078:ackr4b
uniprot id: A0A3Q2QTJ2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:mfge8b
gene id: 8078:mfge8b
uniprot id: A0A3Q2PSU8
uniprot id: A0A3Q2PUJ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:fam160a1a
gene id: 8078:fam160a1a
uniprot id: A0A147AB99
names: Similarity
messages: Belongs to the FHIP family.

8078:tmem182a
gene id: 8078:tmem182a
uniprot id: A0A147A8D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

8078:nol11
gene id: 8078:nol11
uniprot id: A0A3Q2UJY6
names: Subcellular Location Annotation
messages: nucleolus

8078:greb1l
gene id: 8078:greb1l
uniprot id: A0A146P4H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

8078:LOC105925678
gene id: 8078:LOC105925678
uniprot id: A0A3Q2PV38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tollip family.
messages: Cytoplasm

8078:timm44
gene id: 8078:timm44
uniprot id: A0A3Q2QDS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

8078:LOC105921717
gene id: 8078:LOC105921717
uniprot id: A0A147B455
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

8078:ppiab
gene id: 8078:ppiab
uniprot id: A0A3Q2PTB6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8078:LOC105933655
gene id: 8078:LOC105933655
uniprot id: A0A3Q2R1N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8078:LOC105938144
gene id: 8078:LOC105938144
uniprot id: A0A146P7V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

8078:LOC105918028
gene id: 8078:LOC105918028
uniprot id: A0A3Q2PXD3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted
messages: Target cell membrane

8078:LOC105934565
gene id: 8078:LOC105934565
uniprot id: A0A3Q2Q686
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105932938
gene id: 8078:LOC105932938
uniprot id: A0A3Q2STD6
names: Similarity
messages: Belongs to the DeSI family.

8078:tbl1xr1a
gene id: 8078:tbl1xr1a
uniprot id: A0A3Q2PEL0
names: Similarity
messages: Belongs to the WD repeat EBI family.

8078:LOC105915439
gene id: 8078:LOC105915439
uniprot id: A0A3Q2QGA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

8078:txnl4a
gene id: 8078:txnl4a
uniprot id: A0A3Q2TG88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

8078:LOC105935706
gene id: 8078:LOC105935706
uniprot id: A0A3Q2QAG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8078:prickle1a
gene id: 8078:prickle1a
uniprot id: A0A3Q2NY65
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

8078:LOC105917073
gene id: 8078:LOC105917073
uniprot id: A0A3Q2UBI5
names: Similarity
messages: Belongs to the complex I LYR family.

8078:LOC105930638
gene id: 8078:LOC105930638
uniprot id: A0A146P5E6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8078:antxr1d
gene id: 8078:antxr1d
uniprot id: A0A146ZL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

8078:ptgfr
gene id: 8078:ptgfr
uniprot id: A0A3Q2NPE6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:LOC105936260
gene id: 8078:LOC105936260
uniprot id: A0A3Q2NZV4
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105929885
gene id: 8078:LOC105929885
uniprot id: A0A3Q2PGS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

8078:si:ch211-87j1.4
gene id: 8078:si:ch211-87j1.4
uniprot id: A0A3Q2PCP3
names: Similarity
messages: Belongs to the TMEM178 family.

8078:LOC105939993
gene id: 8078:LOC105939993
uniprot id: A0A3Q2PJZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:fam219b
gene id: 8078:fam219b
uniprot id: A0A3Q2PDA2
names: Similarity
messages: Belongs to the FAM219 family.

8078:npm1b
gene id: 8078:npm1b
uniprot id: A0A3Q2QZA0
names: Similarity
messages: Belongs to the nucleoplasmin family.

8078:zgc:154058
gene id: 8078:zgc:154058
uniprot id: A0A3Q2Q5D2
names: Subcellular Location Annotation
messages: Membrane

8078:nadk2
gene id: 8078:nadk2
uniprot id: A0A3Q2P2E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

8078:LOC105931893
gene id: 8078:LOC105931893
uniprot id: A0A3Q2Q352
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:dym
gene id: 8078:dym
uniprot id: A0A3Q2NVV1
names: Similarity
messages: Belongs to the dymeclin family.

8078:senp3b
gene id: 8078:senp3b
uniprot id: A0A147AWS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

8078:gdpgp1
gene id: 8078:gdpgp1
uniprot id: A0A3Q2P872
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDPGP1 family.
messages: Cytoplasm
messages: Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.

8078:tlcd1
gene id: 8078:tlcd1
uniprot id: A0A147AWZ1
names: Subcellular Location Annotation
messages: Membrane

8078:p2ry8
gene id: 8078:p2ry8
uniprot id: A0A3Q2T4K3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:aida
gene id: 8078:aida
uniprot id: A0A3Q2R387
names: Similarity
messages: Belongs to the AIDA family.

8078:mrto4
gene id: 8078:mrto4
uniprot id: A0A3Q2Q3K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

8078:tut1
gene id: 8078:tut1
uniprot id: A0A3Q2QBS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Nucleus speckle
messages: nucleolus

8078:sema6a
gene id: 8078:sema6a
uniprot id: A0A147A0W5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:pdk4
gene id: 8078:pdk4
uniprot id: C6ZDP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8078:dpm1
gene id: 8078:dpm1
uniprot id: A0A3Q2QPG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex.

8078:arhgef7b
gene id: 8078:arhgef7b
uniprot id: A0A3Q2Q2F9
names: Subcellular Location Annotation
messages: lamellipodium

8078:pkn3
gene id: 8078:pkn3
uniprot id: A0A3Q2QCY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

8078:ndufc2
gene id: 8078:ndufc2
uniprot id: A0A3Q2QR14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane

8078:stag1a
gene id: 8078:stag1a
uniprot id: A0A3Q2PQJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

8078:hspa4l
gene id: 8078:hspa4l
uniprot id: A0A3Q2P6Y1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8078:bcl9
gene id: 8078:bcl9
uniprot id: A0A3Q2UKT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

8078:LOC105930426
gene id: 8078:LOC105930426
uniprot id: A0A3Q2PG54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8078:tmcc1b
gene id: 8078:tmcc1b
uniprot id: A0A3Q2Q8W5
names: Similarity
messages: Belongs to the TEX28 family.

8078:star
gene id: 8078:star
uniprot id: A0A3Q2P844
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

8078:zfhx2
gene id: 8078:zfhx2
uniprot id: A0A3Q2SZA9
names: Subcellular Location Annotation
messages: Nucleus

8078:entpd3
gene id: 8078:entpd3
uniprot id: A0A3Q2QB12
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8078:LOC105938719
gene id: 8078:LOC105938719
uniprot id: A0A3Q2NZU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8078:cpm
gene id: 8078:cpm
uniprot id: A0A146ZP65
names: Similarity
messages: Belongs to the peptidase M14 family.

8078:dbx1a
gene id: 8078:dbx1a
uniprot id: A0A146ZZL4
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105918865
gene id: 8078:LOC105918865
uniprot id: A0A3Q2QEM9
uniprot id: A0A3Q2QGA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:ola1
gene id: 8078:ola1
uniprot id: A0A3Q2P6B8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: nucleolus

8078:si:ch211-216b21.2
gene id: 8078:si:ch211-216b21.2
uniprot id: A0A3Q2PZ36
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8078:LOC105925557
gene id: 8078:LOC105925557
uniprot id: A0A3Q2Q2T5
names: Similarity
messages: Belongs to the peptidase C65 family.

8078:LOC105930240
gene id: 8078:LOC105930240
uniprot id: A0A3Q2QVK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8078:ppp1r1b
gene id: 8078:ppp1r1b
uniprot id: A0A3Q2PF36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein phosphatase inhibitor 1 family.
messages: Cytoplasm
messages: Inhibitor of protein-phosphatase 1.

8078:pdia4
gene id: 8078:pdia4
uniprot id: A0A146Z3N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8078:fahd2a
gene id: 8078:fahd2a
uniprot id: A0A3Q2Q1Q7
names: Similarity
messages: Belongs to the FAH family.

8078:LOC105935717
gene id: 8078:LOC105935717
uniprot id: A0A3Q2NTS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8078:slc25a40
gene id: 8078:slc25a40
uniprot id: A0A3Q2QVU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:stxbp5b
gene id: 8078:stxbp5b
uniprot id: A0A146ZYM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8078:ltb4r2a
gene id: 8078:ltb4r2a
uniprot id: A0A3Q2UAR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:LOC105937131
gene id: 8078:LOC105937131
uniprot id: A0A3Q2PA14
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:coq2
gene id: 8078:coq2
uniprot id: A0A3Q2Q8P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

8078:mvda
gene id: 8078:mvda
uniprot id: A0A3Q2TRR7
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

8078:acvr1ba
gene id: 8078:acvr1ba
uniprot id: A0A147A6C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8078:gata2b
gene id: 8078:gata2b
uniprot id: A0A147AA00
names: Subcellular Location Annotation
messages: Nucleus

8078:lrit1a
gene id: 8078:lrit1a
uniprot id: A0A3Q2R1B9
names: Subcellular Location Annotation
messages: Membrane

8078:pik3c3
gene id: 8078:pik3c3
uniprot id: A0A146P539
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
messages: Midbody

8078:kcnmb2
gene id: 8078:kcnmb2
uniprot id: A0A147ACV8
names: Subcellular Location Annotation
messages: Membrane

8078:cd81a
gene id: 8078:cd81a
uniprot id: A0A3Q2QWN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:LOC105939295
gene id: 8078:LOC105939295
uniprot id: A0A146P806
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Nucleus
messages: telomere

8078:cpeb2
gene id: 8078:cpeb2
uniprot id: A0A3Q2QMM3
names: Similarity
messages: Belongs to the RRM CPEB family.

8078:LOC105917523
gene id: 8078:LOC105917523
uniprot id: A0A3Q2QV55
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

8078:galr2b
gene id: 8078:galr2b
uniprot id: A0A147B449
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8078:tefb
gene id: 8078:tefb
uniprot id: A0A146YD29
uniprot id: A0A3Q2PY17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

8078:msh5
gene id: 8078:msh5
uniprot id: A0A3Q2PJN2
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

8078:smarcd2
gene id: 8078:smarcd2
uniprot id: A0A3Q2PNP6
names: Similarity
messages: Belongs to the SMARCD family.

8078:msx2b
gene id: 8078:msx2b
uniprot id: A0A147B4L6
names: Subcellular Location Annotation
messages: Nucleus

8078:ogg1
gene id: 8078:ogg1
uniprot id: A0A3Q2SSW2
names: Similarity
messages: Belongs to the type-1 OGG1 family.

8078:gpr183a
gene id: 8078:gpr183a
uniprot id: A0A3Q2QJD3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:LOC105935110
gene id: 8078:LOC105935110
uniprot id: A0A3Q2T0U7
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8078:LOC105928007
gene id: 8078:LOC105928007
uniprot id: A0A3Q2PTR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

8078:pcsk1
gene id: 8078:pcsk1
uniprot id: A0A3Q2R4F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
messages: Vesicle
messages: secretory vesicle

8078:vill
gene id: 8078:vill
uniprot id: A0A3Q2PGQ8
names: Similarity
messages: Belongs to the villin/gelsolin family.

8078:esama
gene id: 8078:esama
uniprot id: A0A3Q2NVN7
names: Subcellular Location Annotation
messages: Membrane

8078:borcs5
gene id: 8078:borcs5
uniprot id: A0A3Q2PXC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

8078:LOC105929951
gene id: 8078:LOC105929951
uniprot id: A0A3Q2QGP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:scamp1
gene id: 8078:scamp1
uniprot id: A0A3Q2TVI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8078:smad3b
gene id: 8078:smad3b
uniprot id: A0A3Q2R110
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8078:elmo1
gene id: 8078:elmo1
uniprot id: A0A3Q2P3X9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

8078:emc4
gene id: 8078:emc4
uniprot id: A0A146PKA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC4 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:syt1b
gene id: 8078:syt1b
uniprot id: A0A3Q2NV90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

8078:cplx3b
gene id: 8078:cplx3b
uniprot id: A0A146WFL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8078:cdr2a
gene id: 8078:cdr2a
uniprot id: A0A3Q2QPG3
names: Similarity
messages: Belongs to the CDR2 family.

8078:rngtt
gene id: 8078:rngtt
uniprot id: A0A3Q2PZW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

8078:casc3
gene id: 8078:casc3
uniprot id: A0A3Q2PLL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASC3 family.
messages: Nucleus speckle
messages: dendrite
messages: perinuclear region

8078:LOC105939784
gene id: 8078:LOC105939784
uniprot id: A0A3Q2Q902
names: Similarity
messages: Belongs to the intermediate filament family.

8078:gnsa
gene id: 8078:gnsa
uniprot id: A0A3Q2U4S6
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8078:LOC105936384
gene id: 8078:LOC105936384
uniprot id: A0A3Q2NQ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

8078:LOC105919772
gene id: 8078:LOC105919772
uniprot id: A0A3Q2PVX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

8078:LOC105935984
gene id: 8078:LOC105935984
uniprot id: A0A3Q2PPW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8078:srsf2a
gene id: 8078:srsf2a
uniprot id: A0A3Q2QL53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus

8078:mpp2a
gene id: 8078:mpp2a
uniprot id: A0A3Q2PWJ1
names: Similarity
messages: Belongs to the MAGUK family.

8078:zgc:110158
gene id: 8078:zgc:110158
uniprot id: A0A146MPD9
uniprot id: A0A146V1S5
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105921579
gene id: 8078:LOC105921579
uniprot id: A0A3Q2PQE0
names: Similarity
messages: Belongs to the cystatin family.

8078:sema3b
gene id: 8078:sema3b
uniprot id: A0A147A626
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:inha
gene id: 8078:inha
uniprot id: Q5MCQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
messages: Secreted

8078:fgf10b
gene id: 8078:fgf10b
uniprot id: A0A3Q2P0T4
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8078:LOC105926463
gene id: 8078:LOC105926463
uniprot id: A0A3Q2PBT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

8078:rgra
gene id: 8078:rgra
uniprot id: A0A3Q2Q1C1
names: Subcellular Location Annotation
messages: Membrane

8078:ppp5c
gene id: 8078:ppp5c
uniprot id: A0A3Q2UP45
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

8078:iars1
gene id: 8078:iars1
uniprot id: A0A3Q2QRD1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8078:LOC105924267
gene id: 8078:LOC105924267
uniprot id: A0A3Q2PFD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8078:anxa5b
gene id: 8078:anxa5b
uniprot id: A0A3Q2T3S7
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8078:six3a
gene id: 8078:six3a
uniprot id: A0A146PAH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

8078:si:ch1073-284b18.2
gene id: 8078:si:ch1073-284b18.2
uniprot id: A0A146VAM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

8078:slc39a9
gene id: 8078:slc39a9
uniprot id: A0A3Q2QCK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: May act as a zinc-influx transporter.
messages: Membrane

8078:LOC105940026
gene id: 8078:LOC105940026
uniprot id: A0A146ZIE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

8078:LOC105936313
gene id: 8078:LOC105936313
uniprot id: A0A3Q2U0M9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105938599
gene id: 8078:LOC105938599
uniprot id: A0A3Q2P8D4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8078:LOC105936635
gene id: 8078:LOC105936635
uniprot id: A0A3Q2PDD6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

8078:LOC105930878
gene id: 8078:LOC105930878
uniprot id: A0A147A1V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8078:znf703
gene id: 8078:znf703
uniprot id: A0A3Q2SXG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

8078:npepps
gene id: 8078:npepps
uniprot id: A0A147A116
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8078:atxn10
gene id: 8078:atxn10
uniprot id: A0A3Q2P6V4
names: Function
names: Similarity
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.

8078:rps24
gene id: 8078:rps24
uniprot id: A0A3Q2Q1V0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

8078:akt1
gene id: 8078:akt1
uniprot id: A0A146YLY1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

8078:use1
gene id: 8078:use1
uniprot id: A0A3Q2QBB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:pus1
gene id: 8078:pus1
uniprot id: A0A3Q2P9P1
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

8078:ndufv1
gene id: 8078:ndufv1
uniprot id: A0A3Q2PBE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

8078:ccdc135
gene id: 8078:ccdc135
uniprot id: A0A3Q2NWD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC7 family.
messages: cilium axoneme
messages: flagellum
messages: flagellum axoneme

8078:pbx2
gene id: 8078:pbx2
uniprot id: A0A3Q2PHZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8078:kif3b
gene id: 8078:kif3b
uniprot id: A0A3Q2T7X3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8078:sec61g
gene id: 8078:sec61g
uniprot id: A0A3Q2ST14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:dhcr7
gene id: 8078:dhcr7
uniprot id: A0A3Q2PTS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

8078:ndufb3
gene id: 8078:ndufb3
uniprot id: A0A3Q2PTQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

8078:lipeb
gene id: 8078:lipeb
uniprot id: A0A3Q2QEX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'GDXG' lipolytic enzyme family.
messages: Cell membrane
messages: Lipid droplet
messages: caveola
messages: cytosol

8078:slc35a5
gene id: 8078:slc35a5
uniprot id: A0A146RPL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

8078:lrit1b
gene id: 8078:lrit1b
uniprot id: A0A3Q2UCM0
names: Subcellular Location Annotation
messages: Membrane

8078:trappc5
gene id: 8078:trappc5
uniprot id: A0A3Q2P7E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

8078:phykpl
gene id: 8078:phykpl
uniprot id: A0A147B5T7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

8078:mogat3b
gene id: 8078:mogat3b
uniprot id: A0A3Q2SRH2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:stx17
gene id: 8078:stx17
uniprot id: A0A3Q2UH43
names: Similarity
messages: Belongs to the syntaxin family.

8078:LOC105920501
gene id: 8078:LOC105920501
uniprot id: A0A3Q2QQ92
names: Similarity
messages: Belongs to the DDRGK1 family.

8078:amotl2a
gene id: 8078:amotl2a
uniprot id: A0A3Q2QI10
names: Similarity
messages: Belongs to the angiomotin family.

8078:tmem45a
gene id: 8078:tmem45a
uniprot id: A0A3Q2QM33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

8078:zgc:92907
gene id: 8078:zgc:92907
uniprot id: A0A3Q2TDJ1
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

8078:LOC105934703
gene id: 8078:LOC105934703
uniprot id: A0A147B644
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

8078:cd40
gene id: 8078:cd40
uniprot id: A0A3Q2ST21
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:plp2
gene id: 8078:plp2
uniprot id: A0A3Q2R2I2
names: Subcellular Location Annotation
messages: Membrane

8078:thrap3a
gene id: 8078:thrap3a
uniprot id: A0A3Q2NMZ6
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

8078:rabggtb
gene id: 8078:rabggtb
uniprot id: A0A3Q2QEA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

8078:hoxc9a
gene id: 8078:hoxc9a
uniprot id: A0A147A6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8078:tmem218
gene id: 8078:tmem218
uniprot id: A0A3Q2Q8S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

8078:trex4
gene id: 8078:trex4
uniprot id: A0A3Q2QXK4
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

8078:tbxa2r
gene id: 8078:tbxa2r
uniprot id: A0A3Q2QVX0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:hoxa3a
gene id: 8078:hoxa3a
uniprot id: A0A3Q2QNV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8078:rflnb
gene id: 8078:rflnb
uniprot id: A0A146ZQG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

8078:LOC105938314
gene id: 8078:LOC105938314
uniprot id: A0A3Q2QVR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 26 family.
messages: Nucleus

8078:prr5a
gene id: 8078:prr5a
uniprot id: A0A3Q2PXR0
names: Similarity
messages: Belongs to the PROTOR family.

8078:dlx6a
gene id: 8078:dlx6a
uniprot id: A0A146ZV06
names: Subcellular Location Annotation
messages: Nucleus

8078:hs3st1l2
gene id: 8078:hs3st1l2
uniprot id: A0A3Q2TUT9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8078:LOC105934246
gene id: 8078:LOC105934246
uniprot id: A0A146ZV26
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

8078:ccnd2a
gene id: 8078:ccnd2a
uniprot id: A0A3Q2QIH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus

8078:areg
gene id: 8078:areg
uniprot id: A0A3Q2NZ87
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:gipc2
gene id: 8078:gipc2
uniprot id: A0A3Q2SV98
names: Similarity
messages: Belongs to the GIPC family.

8078:nmba
gene id: 8078:nmba
uniprot id: A0A3Q2Q832
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted

8078:lpar2b
gene id: 8078:lpar2b
uniprot id: A0A3Q2QYS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

8078:hsc70
gene id: 8078:hsc70
uniprot id: A0A147APF5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8078:timm10
gene id: 8078:timm10
uniprot id: A0A3Q2QPC5
names: Function
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.

8078:mrpl23
gene id: 8078:mrpl23
uniprot id: A0A3Q2PBC3
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

8078:nkx2.5
gene id: 8078:nkx2.5
uniprot id: A0A3Q2P2U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NK-2 homeobox family.
messages: Nucleus

8078:si:ch211-198n5.11
gene id: 8078:si:ch211-198n5.11
uniprot id: A0A3Q2P8F2
names: Similarity
messages: Belongs to the AccD/PCCB family.

8078:LOC105932597
gene id: 8078:LOC105932597
uniprot id: A0A3Q2QTI9
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8078:gata4
gene id: 8078:gata4
uniprot id: A0A3Q2NNI8
names: Subcellular Location Annotation
messages: Nucleus

8078:rpf2
gene id: 8078:rpf2
uniprot id: A0A3Q2UBN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

8078:coro2ba
gene id: 8078:coro2ba
uniprot id: A0A147AZ80
names: Similarity
messages: Belongs to the WD repeat coronin family.

8078:pa2g4a
gene id: 8078:pa2g4a
uniprot id: A0A146P7B3
names: Similarity
messages: Belongs to the peptidase M24 family.

8078:dcst1
gene id: 8078:dcst1
uniprot id: A0A3Q2QV83
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105918027
gene id: 8078:LOC105918027
uniprot id: A0A3Q2PV55
uniprot id: A0A3Q2QX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

8078:cnot2
gene id: 8078:cnot2
uniprot id: A0A146P420
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

8078:llph
gene id: 8078:llph
uniprot id: A0A3Q2P294
names: Similarity
messages: Belongs to the learning-associated protein family.

8078:supt20
gene id: 8078:supt20
uniprot id: A0A146PZC6
names: Similarity
messages: Belongs to the SPT20 family.

8078:kdm5c
gene id: 8078:kdm5c
uniprot id: A0A3Q2R1F3
uniprot id: A0A3Q2UPS2
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

8078:LOC105929556
gene id: 8078:LOC105929556
uniprot id: A0A3Q2R222
names: Similarity
messages: Belongs to the peptidase S9A family.

8078:cks2
gene id: 8078:cks2
uniprot id: A0A3Q2UQ93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

8078:LOC105916452
gene id: 8078:LOC105916452
uniprot id: A0A3Q2PEY9
names: Subcellular Location Annotation
messages: Cytoplasm

8078:LOC105917274
gene id: 8078:LOC105917274
uniprot id: A0A3Q2NQ38
names: Similarity
messages: Belongs to the DCC1 family.

8078:nup88
gene id: 8078:nup88
uniprot id: A0A147A2W5
names: Subcellular Location Annotation
messages: nuclear pore complex

8078:cdc42ep3
gene id: 8078:cdc42ep3
uniprot id: A0A3Q2Q1P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8078:capn3b
gene id: 8078:capn3b
uniprot id: A0A147A1T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

8078:LOC105920700
gene id: 8078:LOC105920700
uniprot id: A0A146N8W4
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

8078:dse
gene id: 8078:dse
uniprot id: A0A3Q2QD06
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

8078:fip1l1b
gene id: 8078:fip1l1b
uniprot id: A0A3Q2NUK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

8078:fgf4
gene id: 8078:fgf4
uniprot id: A0A3Q2QZG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

8078:LOC105931109
gene id: 8078:LOC105931109
uniprot id: A0A3Q2SX37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

8078:mmp14b
gene id: 8078:mmp14b
uniprot id: A0A3Q2QWI1
names: Similarity
messages: Belongs to the peptidase M10A family.

8078:slc39a8
gene id: 8078:slc39a8
uniprot id: A0A3Q2PDC4
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105921350
gene id: 8078:LOC105921350
uniprot id: A0A3Q2NYH0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:b3gnt7l
gene id: 8078:b3gnt7l
uniprot id: A0A146RFC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:kpnb1
gene id: 8078:kpnb1
uniprot id: A0A3Q2PY90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

8078:ssr3
gene id: 8078:ssr3
uniprot id: A0A3Q2NPB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

8078:tmem65
gene id: 8078:tmem65
uniprot id: A0A3Q2PFY7
names: Subcellular Location Annotation
messages: Membrane

8078:chsy1
gene id: 8078:chsy1
uniprot id: A0A3Q2TM64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8078:rps6ka1
gene id: 8078:rps6ka1
uniprot id: A0A146WY28
uniprot id: A0A3Q2SY22
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8078:si:ch211-251b21.1
gene id: 8078:si:ch211-251b21.1
uniprot id: A0A146XTB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8078:cdc5l
gene id: 8078:cdc5l
uniprot id: A0A3Q2PH78
names: Similarity
messages: Belongs to the CEF1 family.

8078:cdx4
gene id: 8078:cdx4
uniprot id: A0A3Q2PN75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

8078:tle2a
gene id: 8078:tle2a
uniprot id: A0A3Q2Q8A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8078:tmem269
gene id: 8078:tmem269
uniprot id: A0A3Q2QEH2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

8078:tbl1x
gene id: 8078:tbl1x
uniprot id: A0A3Q2PZ98
names: Similarity
messages: Belongs to the WD repeat EBI family.

8078:eef1akmt1
gene id: 8078:eef1akmt1
uniprot id: A0A146V5I5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

8078:sart3
gene id: 8078:sart3
uniprot id: A0A3Q2QRI7
names: Subcellular Location Annotation
messages: nucleoplasm

8078:txnl4b
gene id: 8078:txnl4b
uniprot id: A0A3Q2PKM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

8078:KEG95 p06
gene id: 8078:KEG95_p06
uniprot id: B7U7X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

8078:msx1a
gene id: 8078:msx1a
uniprot id: A0A146ZZW6
names: Subcellular Location Annotation
messages: Nucleus

8078:notch1a
gene id: 8078:notch1a
uniprot id: A0A3Q2P3Q3
uniprot id: A0A3Q2QEQ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

8078:atp6v0b
gene id: 8078:atp6v0b
uniprot id: A0A147B0Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

8078:usp2a
gene id: 8078:usp2a
uniprot id: A0A146P676
uniprot id: A0A3Q2PY14
names: Similarity
messages: Belongs to the peptidase C19 family.

8078:LOC105932290
gene id: 8078:LOC105932290
uniprot id: A0A3Q2NSN7
names: Similarity
messages: Belongs to the BRAG family.

8078:LOC105923602
gene id: 8078:LOC105923602
uniprot id: A0A146P4B2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:tatdn2
gene id: 8078:tatdn2
uniprot id: A0A3Q2SZM4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

8078:ikbke
gene id: 8078:ikbke
uniprot id: A0A146VRV0
names: Subcellular Location Annotation
messages: Cytoplasm

8078:taf7
gene id: 8078:taf7
uniprot id: A0A3Q2PR23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

8078:LOC105931408
gene id: 8078:LOC105931408
uniprot id: A0A146MYJ1
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

8078:hoxd4a
gene id: 8078:hoxd4a
uniprot id: A0A3Q2P331
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8078:hoxd11a
gene id: 8078:hoxd11a
uniprot id: A0A3Q2P431
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8078:clic5b
gene id: 8078:clic5b
uniprot id: A0A3Q2PYS4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8078:ddah2
gene id: 8078:ddah2
uniprot id: A0A147A045
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

8078:acss2l
gene id: 8078:acss2l
uniprot id: A0A3Q2U1B1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8078:rpa3
gene id: 8078:rpa3
uniprot id: A0A3Q2QV74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

8078:LOC105925392
gene id: 8078:LOC105925392
uniprot id: A0A3Q2PF88
names: Subcellular Location Annotation
messages: extracellular space

8078:gtf2a1
gene id: 8078:gtf2a1
uniprot id: A0A3Q2SV66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

8078:pycr3
gene id: 8078:pycr3
uniprot id: A0A3Q2U688
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

8078:LOC105933333
gene id: 8078:LOC105933333
uniprot id: A0A146ZY60
names: Similarity
messages: Belongs to the pyridoxine kinase family.

8078:smarcd1
gene id: 8078:smarcd1
uniprot id: A0A146P7L8
names: Similarity
messages: Belongs to the SMARCD family.

8078:LOC105931013
gene id: 8078:LOC105931013
uniprot id: A0A146P9K2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

8078:LOC105935931
gene id: 8078:LOC105935931
uniprot id: A0A3Q2PUK3
uniprot id: A0A3Q2QVR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

8078:dmgdh
gene id: 8078:dmgdh
uniprot id: A0A147AT58
names: Similarity
messages: Belongs to the GcvT family.

8078:LOC105927325
gene id: 8078:LOC105927325
uniprot id: A0A3Q2R3Y4
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105937021
gene id: 8078:LOC105937021
uniprot id: A0A3Q2Q0H0
names: Subcellular Location Annotation
messages: Membrane

8078:gorasp2
gene id: 8078:gorasp2
uniprot id: A0A3Q2PUW1
names: Similarity
messages: Belongs to the GORASP family.

8078:chrd
gene id: 8078:chrd
uniprot id: A0A147AAR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chordin family.
messages: Secreted

8078:eif3ba
gene id: 8078:eif3ba
uniprot id: A0A3Q2NRT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

8078:junbb
gene id: 8078:junbb
uniprot id: A0A146P7B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8078:agt
gene id: 8078:agt
uniprot id: A0A3Q2PZR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

8078:polr1f
gene id: 8078:polr1f
uniprot id: A0A3Q2TA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

8078:med29
gene id: 8078:med29
uniprot id: A0A3Q2P143
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 29 family.
messages: Nucleus

8078:LOC105940237
gene id: 8078:LOC105940237
uniprot id: A0A3Q2NQJ9
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

8078:bnip4
gene id: 8078:bnip4
uniprot id: A0A3Q2QYE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

8078:LOC105933396
gene id: 8078:LOC105933396
uniprot id: A0A3Q2P9X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:LOC105927111
gene id: 8078:LOC105927111
uniprot id: A0A146P5U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

8078:LOC105927012
gene id: 8078:LOC105927012
uniprot id: A0A3Q2UIP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

8078:LOC105933269
gene id: 8078:LOC105933269
uniprot id: A0A3Q2NWM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8078:sgtb
gene id: 8078:sgtb
uniprot id: A0A147B452
names: Similarity
messages: Belongs to the SGT family.

8078:stambpl1
gene id: 8078:stambpl1
uniprot id: A0A147B0H1
names: Similarity
messages: Belongs to the peptidase M67C family.

8078:ipmkb
gene id: 8078:ipmkb
uniprot id: A0A3Q2NUK7
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8078:retreg3
gene id: 8078:retreg3
uniprot id: A0A146YXB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Membrane

8078:agxtb
gene id: 8078:agxtb
uniprot id: A0A146VA34
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

8078:LOC105919204
gene id: 8078:LOC105919204
uniprot id: A0A3Q2R0F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

8078:LOC105925566
gene id: 8078:LOC105925566
uniprot id: A0A146NQL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm

8078:coro1b
gene id: 8078:coro1b
uniprot id: A0A3Q2SQ20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat coronin family.
messages: Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction.
messages: stress fiber

8078:LOC105925196
gene id: 8078:LOC105925196
uniprot id: A0A3Q2QSC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:zgc:101744
gene id: 8078:zgc:101744
uniprot id: A0A3Q2T3M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

8078:LOC105917155
gene id: 8078:LOC105917155
uniprot id: A0A3Q2P2N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

8078:rae1
gene id: 8078:rae1
uniprot id: A0A3Q2U472
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat rae1 family.
messages: spindle pole

8078:spns2
gene id: 8078:spns2
uniprot id: A0A3Q2PMW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

8078:LOC105932301
gene id: 8078:LOC105932301
uniprot id: A0A146W698
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8078:LOC105936839
gene id: 8078:LOC105936839
uniprot id: A0A146P6C0
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

8078:slc35f6
gene id: 8078:slc35f6
uniprot id: A0A3Q2Q3N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

8078:top2a
gene id: 8078:top2a
uniprot id: A0A3Q2U469
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

8078:LOC105929594
gene id: 8078:LOC105929594
uniprot id: A0A3Q2Q0J5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:ttc38
gene id: 8078:ttc38
uniprot id: A0A3Q2NYU5
names: Similarity
messages: Belongs to the TTC38 family.

8078:spopla
gene id: 8078:spopla
uniprot id: A0A3Q2PBA9
names: Similarity
messages: Belongs to the Tdpoz family.

8078:LOC105937129
gene id: 8078:LOC105937129
uniprot id: A0A3Q2QFJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8078:csgalnact1a
gene id: 8078:csgalnact1a
uniprot id: A0A3Q2R4N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8078:ppp1r14c
gene id: 8078:ppp1r14c
uniprot id: A0A3Q2T0N0
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8078:LOC105935395
gene id: 8078:LOC105935395
uniprot id: A0A3Q2PRA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

8078:rps8a
gene id: 8078:rps8a
uniprot id: A0A147AWH2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

8078:prkab2
gene id: 8078:prkab2
uniprot id: A0A146MVT0
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

8078:LOC105916443
gene id: 8078:LOC105916443
uniprot id: A0A3Q2PX38
uniprot id: A0A3Q2TMX8
names: Similarity
messages: Belongs to the PROTOR family.

8078:ndufa12
gene id: 8078:ndufa12
uniprot id: A0A3Q2SS75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8078:prdm2b
gene id: 8078:prdm2b
uniprot id: A0A3Q2TKR1
names: Subcellular Location Annotation
messages: Nucleus

8078:pigv
gene id: 8078:pigv
uniprot id: A0A3Q2PL62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

8078:prorp
gene id: 8078:prorp
uniprot id: A0A146NQH5
names: Similarity
messages: Belongs to the PPR family. P subfamily.

8078:pard6gb
gene id: 8078:pard6gb
uniprot id: A0A3Q2PVN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

8078:gamt
gene id: 8078:gamt
uniprot id: A0A3Q2PQS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor.
messages: Monomer.

8078:lypla2
gene id: 8078:lypla2
uniprot id: A0A3Q2QQK7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

8078:bcam
gene id: 8078:bcam
uniprot id: A0A3Q2QKT2
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105935575
gene id: 8078:LOC105935575
uniprot id: A0A146ZS74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8078:slc49a3
gene id: 8078:slc49a3
uniprot id: A0A3Q2UF72
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105924967
gene id: 8078:LOC105924967
uniprot id: A0A146PAK9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8078:LOC105928214
gene id: 8078:LOC105928214
uniprot id: A0A146WRZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

8078:tgm1l1
gene id: 8078:tgm1l1
uniprot id: A0A3Q2P199
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8078:LOC105916426
gene id: 8078:LOC105916426
uniprot id: A0A3Q2QQF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: Secreted
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

8078:dpysl2a
gene id: 8078:dpysl2a
uniprot id: A0A3Q2Q942
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

8078:mterf3
gene id: 8078:mterf3
uniprot id: A0A3Q2PHX9
names: Similarity
messages: Belongs to the mTERF family.

8078:rps9
gene id: 8078:rps9
uniprot id: A0A3Q2TG40
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs.

8078:mblac1
gene id: 8078:mblac1
uniprot id: A0A3Q2PKH4
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8078:igfbp2a
gene id: 8078:igfbp2a
uniprot id: A0A146SI87
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:tmem184c
gene id: 8078:tmem184c
uniprot id: A0A3Q2P4D8
names: Subcellular Location Annotation
messages: Membrane

8078:opn3
gene id: 8078:opn3
uniprot id: A0A3Q2Q0K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8078:myca
gene id: 8078:myca
uniprot id: A0A3Q2QM26
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

8078:ube2nb
gene id: 8078:ube2nb
uniprot id: A0A147B537
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:slc26a3.1
gene id: 8078:slc26a3.1
uniprot id: A0A3Q2QTM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Chloride/bicarbonate exchanger.
messages: Membrane

8078:srrd
gene id: 8078:srrd
uniprot id: A0A3Q2T6T0
names: Similarity
messages: Belongs to the SRR1 family.

8078:desmb
gene id: 8078:desmb
uniprot id: A0A146P3X6
names: Similarity
messages: Belongs to the intermediate filament family.

8078:nkx2.2a
gene id: 8078:nkx2.2a
uniprot id: A0A3Q2P4H0
names: Subcellular Location Annotation
messages: Nucleus

8078:st6galnac
gene id: 8078:st6galnac
uniprot id: A0A3Q2TA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8078:LOC105926042
gene id: 8078:LOC105926042
uniprot id: A0A147ABD1
names: Similarity
messages: Belongs to the dysbindin family.

8078:LOC105922003
gene id: 8078:LOC105922003
uniprot id: A0A3Q2NN84
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

8078:prim2
gene id: 8078:prim2
uniprot id: A0A3Q2Q406
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

8078:timp2a
gene id: 8078:timp2a
uniprot id: A0A3Q2QKU4
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

8078:rnf157
gene id: 8078:rnf157
uniprot id: A0A3Q2PC55
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

8078:kpna3
gene id: 8078:kpna3
uniprot id: A0A3Q2QND0
names: Similarity
messages: Belongs to the importin alpha family.

8078:cdh2
gene id: 8078:cdh2
uniprot id: A0A3Q2QRX8
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8078:LOC105922255
gene id: 8078:LOC105922255
uniprot id: A0A147B655
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8078:rybpb
gene id: 8078:rybpb
uniprot id: A0A3Q2PSH8
names: Subcellular Location Annotation
messages: Nucleus

8078:irf3
gene id: 8078:irf3
uniprot id: A0A3Q2SRL0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:ppifa
gene id: 8078:ppifa
uniprot id: A0A3Q2PZS5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8078:LOC105937192
gene id: 8078:LOC105937192
uniprot id: A0A3Q2P2Y4
names: Subcellular Location Annotation
messages: Membrane

8078:skap1
gene id: 8078:skap1
uniprot id: A0A146ZS30
names: Similarity
messages: Belongs to the SKAP family.

8078:prkar1ab
gene id: 8078:prkar1ab
uniprot id: A0A3Q2P2V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

8078:hyal2a
gene id: 8078:hyal2a
uniprot id: A0A146ZW78
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8078:LOC105921530
gene id: 8078:LOC105921530
uniprot id: A0A146XQS5
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

8078:psmc5
gene id: 8078:psmc5
uniprot id: A0A3Q2PP58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

8078:uba52
gene id: 8078:uba52
uniprot id: A0A3Q2QSU2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

8078:LOC105916889
gene id: 8078:LOC105916889
uniprot id: A0A3Q2PNR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

8078:bicd2
gene id: 8078:bicd2
uniprot id: A0A3Q2P0T1
names: Similarity
messages: Belongs to the BicD family.

8078:slc6a17
gene id: 8078:slc6a17
uniprot id: A0A147A0V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8078:pdhb
gene id: 8078:pdhb
uniprot id: A0A3Q2U6L0
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

8078:nup133
gene id: 8078:nup133
uniprot id: A0A3Q2U073
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

8078:fan1
gene id: 8078:fan1
uniprot id: A0A3Q2UAY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

8078:vars1
gene id: 8078:vars1
uniprot id: A0A3Q2P9S8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8078:plxna2
gene id: 8078:plxna2
uniprot id: A0A3Q2QDG5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105928915
gene id: 8078:LOC105928915
uniprot id: A0A3Q2Q5S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8078:slc12a1
gene id: 8078:slc12a1
uniprot id: A0A146ZRX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

8078:LOC105937286
gene id: 8078:LOC105937286
uniprot id: A0A3Q2NSX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

8078:LOC105939684
gene id: 8078:LOC105939684
uniprot id: A0A3Q2SZ72
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:LOC105932281
gene id: 8078:LOC105932281
uniprot id: A0A3Q2NU45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

8078:clstn1
gene id: 8078:clstn1
uniprot id: A0A3Q2P5B3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

8078:LOC105915965
gene id: 8078:LOC105915965
uniprot id: A0A3Q2UF09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit F family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8078:LOC105932070
gene id: 8078:LOC105932070
uniprot id: A0A3Q2PF44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8078:cdc26
gene id: 8078:cdc26
uniprot id: A0A3Q2NNS3
names: Similarity
messages: Belongs to the CDC26 family.

8078:naa25
gene id: 8078:naa25
uniprot id: A0A3Q2PYY7
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

8078:esrp1
gene id: 8078:esrp1
uniprot id: A0A3Q2PHX8
uniprot id: A0A3Q2TBH2
names: Subcellular Location Annotation
messages: Nucleus

8078:ugdh
gene id: 8078:ugdh
uniprot id: A0A3Q2T1M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

8078:LOC105926415
gene id: 8078:LOC105926415
uniprot id: A0A3Q2T4Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

8078:acsf2
gene id: 8078:acsf2
uniprot id: A0A3Q2U2M3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8078:trmo
gene id: 8078:trmo
uniprot id: A0A3Q2TL69
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

8078:atp5fa1
gene id: 8078:atp5fa1
uniprot id: A0A3Q2QFN1
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

8078:maco1b
gene id: 8078:maco1b
uniprot id: A0A146X5H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

8078:fzd10
gene id: 8078:fzd10
uniprot id: A0A3Q2Q6H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

8078:aqp7
gene id: 8078:aqp7
uniprot id: A0A3Q2Q9L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8078:selenoi
gene id: 8078:selenoi
uniprot id: A0A146WCB1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

8078:tomt
gene id: 8078:tomt
uniprot id: A0A3Q2NSX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Endoplasmic reticulum

8078:ngfb
gene id: 8078:ngfb
uniprot id: A0A3Q2TIE1
names: Similarity
messages: Belongs to the NGF-beta family.

8078:LOC105918398
gene id: 8078:LOC105918398
uniprot id: A0A3Q2NZP6
names: Subcellular Location Annotation
messages: Membrane

8078:coq10b
gene id: 8078:coq10b
uniprot id: A0A3Q2PHU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

8078:dbpb
gene id: 8078:dbpb
uniprot id: A0A146NLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

8078:hoxa2b
gene id: 8078:hoxa2b
uniprot id: Q1KMN0
names: Subcellular Location Annotation
messages: Nucleus

8078:dlx4b
gene id: 8078:dlx4b
uniprot id: A0A3Q2QZG7
names: Subcellular Location Annotation
messages: Nucleus

8078:slc17a5
gene id: 8078:slc17a5
uniprot id: A0A3Q2PBI7
names: Subcellular Location Annotation
messages: Membrane

8078:mrpl22
gene id: 8078:mrpl22
uniprot id: A0A146ZVX0
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

8078:eif3s10
gene id: 8078:eif3s10
uniprot id: A0A3Q2TK65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

8078:LOC105937122
gene id: 8078:LOC105937122
uniprot id: A0A146ZQG3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105931353
gene id: 8078:LOC105931353
uniprot id: A0A146NN14
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

8078:tmed3
gene id: 8078:tmed3
uniprot id: A0A3Q2PEL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

8078:LOC105934150
gene id: 8078:LOC105934150
uniprot id: A0A3Q2SP51
names: Subcellular Location Annotation
messages: Nucleus

8078:slco2b1
gene id: 8078:slco2b1
uniprot id: A0A146XWM9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:csgalnact2
gene id: 8078:csgalnact2
uniprot id: A0A146NFX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8078:timm23a
gene id: 8078:timm23a
uniprot id: A0A146X2N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

8078:LOC105930841
gene id: 8078:LOC105930841
uniprot id: A0A3Q2QV00
names: Subcellular Location Annotation
messages: Nucleus

8078:rpain
gene id: 8078:rpain
uniprot id: A0A3Q2QST7
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105939312
gene id: 8078:LOC105939312
uniprot id: A0A146ZJU2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

8078:gpr137ba
gene id: 8078:gpr137ba
uniprot id: A0A3Q2SWV0
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

8078:cdc34b
gene id: 8078:cdc34b
uniprot id: A0A3Q2Q6Z6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:LOC105918418
gene id: 8078:LOC105918418
uniprot id: A0A3Q2Q9Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

8078:gpr157
gene id: 8078:gpr157
uniprot id: A0A3Q2SW27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 5 family.
messages: Membrane

8078:lhcgr
gene id: 8078:lhcgr
uniprot id: A3KEZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

8078:fis1
gene id: 8078:fis1
uniprot id: A0A3Q2TH78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

8078:uox
gene id: 8078:uox
uniprot id: A0A3Q2QAR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

8078:hoxd9a
gene id: 8078:hoxd9a
uniprot id: A0A3Q2P303
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8078:LOC105928867
gene id: 8078:LOC105928867
uniprot id: Q9PTR1
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:LOC105915360
gene id: 8078:LOC105915360
uniprot id: A0A3Q2T780
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8078:LOC105931052
gene id: 8078:LOC105931052
uniprot id: A0A147A1H0
names: Similarity
messages: Belongs to the RAMP family.

8078:igfbp7
gene id: 8078:igfbp7
uniprot id: A0A3Q2PMS0
names: Subcellular Location Annotation
messages: Membrane

8078:pou3f3b
gene id: 8078:pou3f3b
uniprot id: A0A3Q2U840
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

8078:mrps18b
gene id: 8078:mrps18b
uniprot id: A0A3Q2QVF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily.
messages: Mitochondrion

8078:LOC105916105
gene id: 8078:LOC105916105
uniprot id: A0A3Q2QHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

8078:LOC105917431
gene id: 8078:LOC105917431
uniprot id: A0A3Q2PT98
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

8078:arpp19a
gene id: 8078:arpp19a
uniprot id: A0A3Q2PJC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

8078:LOC105930299
gene id: 8078:LOC105930299
uniprot id: A0A146WHD5
uniprot id: A0A3Q2PVV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

8078:tmem263
gene id: 8078:tmem263
uniprot id: A0A3Q2P3S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

8078:LOC105928424
gene id: 8078:LOC105928424
uniprot id: A0A147A6F2
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105931215
gene id: 8078:LOC105931215
uniprot id: A0A3Q2NR27
names: Subcellular Location Annotation
messages: Nucleus

8078:unkl
gene id: 8078:unkl
uniprot id: A0A3Q2NSB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

8078:si:ch211-217a12.1
gene id: 8078:si:ch211-217a12.1
uniprot id: A0A146Z3I7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

8078:timm8a
gene id: 8078:timm8a
uniprot id: A0A3Q2QPN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8078:lrit3a
gene id: 8078:lrit3a
uniprot id: A0A3Q2P4V0
names: Subcellular Location Annotation
messages: Membrane

8078:txlnbb
gene id: 8078:txlnbb
uniprot id: A0A3Q2NTM1
names: Similarity
messages: Belongs to the taxilin family.

8078:LOC105938431
gene id: 8078:LOC105938431
uniprot id: A0A3Q2QM23
names: Similarity
messages: Belongs to the cystatin family.

8078:rapgef2
gene id: 8078:rapgef2
uniprot id: A0A3Q2PVJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAPGEF2 family.
messages: Cell junction
messages: Endosome
messages: Late endosome
messages: perinuclear region

8078:dynll1
gene id: 8078:dynll1
uniprot id: A0A3Q2P7M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8078:LOC105936189
gene id: 8078:LOC105936189
uniprot id: A0A3Q2P4M6
uniprot id: A0A3Q2P4V7
names: Similarity
messages: Belongs to the peptidase C19 family.

8078:limk2
gene id: 8078:limk2
uniprot id: A0A146WZS0
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

8078:fam49bb
gene id: 8078:fam49bb
uniprot id: A0A146NUY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

8078:tfpi2
gene id: 8078:tfpi2
uniprot id: A0A3Q2UDU6
names: Subcellular Location Annotation
messages: Secreted

8078:LOC105917006
gene id: 8078:LOC105917006
uniprot id: A0A3Q2PGE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:st8sia1
gene id: 8078:st8sia1
uniprot id: A0A3Q2Q094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8078:ephb6
gene id: 8078:ephb6
uniprot id: A0A3Q2QS28
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:rpl13a
gene id: 8078:rpl13a
uniprot id: A0A3Q2STR0
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

8078:gab2
gene id: 8078:gab2
uniprot id: A0A3Q2QPA2
names: Similarity
messages: Belongs to the GAB family.

8078:prtfdc1a
gene id: 8078:prtfdc1a
uniprot id: A0A146ZRY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

8078:med19a
gene id: 8078:med19a
uniprot id: A0A3Q2PJF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8078:itgb8
gene id: 8078:itgb8
uniprot id: A0A3Q2QNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

8078:LOC105929138
gene id: 8078:LOC105929138
uniprot id: A0A3Q2PUW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

8078:mapkapk2a
gene id: 8078:mapkapk2a
uniprot id: A0A3Q2Q017
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:ppp1r15b
gene id: 8078:ppp1r15b
uniprot id: A0A3Q2PXK5
names: Similarity
messages: Belongs to the PPP1R15 family.

8078:LOC105940229
gene id: 8078:LOC105940229
uniprot id: A0A3Q2NQW0
uniprot id: A0A3Q2NQX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

8078:plppr1
gene id: 8078:plppr1
uniprot id: A0A3Q2UEE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: May play a role in neurite outgrowth and neurogenesis.
messages: Membrane
messages: neuron projection

8078:lhx4
gene id: 8078:lhx4
uniprot id: A0A3Q2QA06
names: Subcellular Location Annotation
messages: Nucleus

8078:nop10
gene id: 8078:nop10
uniprot id: A0A3Q2TQ04
names: Similarity
messages: Belongs to the NOP10 family.

8078:LOC105930935
gene id: 8078:LOC105930935
uniprot id: A0A147A1Q0
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin Y subfamily.

8078:zic4
gene id: 8078:zic4
uniprot id: A0A3Q2PRL0
uniprot id: A0A3Q2THL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

8078:LOC105918352
gene id: 8078:LOC105918352
uniprot id: A0A146P9L1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8078:LOC105934098
gene id: 8078:LOC105934098
uniprot id: A0A3Q2Q6P6
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105930946
gene id: 8078:LOC105930946
uniprot id: A0A3Q2PK38
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8078:mfsd11
gene id: 8078:mfsd11
uniprot id: A0A3Q2R247
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

8078:p2ry1
gene id: 8078:p2ry1
uniprot id: A0A3Q2PSK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:LOC105927298
gene id: 8078:LOC105927298
uniprot id: A0A146NWL4
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:ptges
gene id: 8078:ptges
uniprot id: A0A3Q2Q7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

8078:cdk2
gene id: 8078:cdk2
uniprot id: A0A3Q2T0B4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:slc49a4
gene id: 8078:slc49a4
uniprot id: A0A3Q2QTR5
names: Subcellular Location Annotation
messages: Membrane

8078:ing2
gene id: 8078:ing2
uniprot id: A0A3Q2R2B8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8078:p2ry2.1
gene id: 8078:p2ry2.1
uniprot id: A0A3Q2ST74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:LOC105925860
gene id: 8078:LOC105925860
uniprot id: A0A146P762
names: Similarity
messages: Belongs to the SIKE family.

8078:si:ch211-201h21.5
gene id: 8078:si:ch211-201h21.5
uniprot id: A0A3Q2P955
names: Similarity
messages: Belongs to the IUNH family.

8078:sostdc1a
gene id: 8078:sostdc1a
uniprot id: A0A3Q2P7G5
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:timeless
gene id: 8078:timeless
uniprot id: A0A3Q2P483
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Nucleus

8078:LOC105922465
gene id: 8078:LOC105922465
uniprot id: A0A147AK08
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8078:mknk2b
gene id: 8078:mknk2b
uniprot id: A0A3Q2R1J2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:entpd1
gene id: 8078:entpd1
uniprot id: A0A3Q2TPB9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8078:katnal1
gene id: 8078:katnal1
uniprot id: A0A147A8A7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

8078:faxcb
gene id: 8078:faxcb
uniprot id: A0A3Q2P9I2
names: Similarity
messages: Belongs to the FAX family.

8078:parp1
gene id: 8078:parp1
uniprot id: A0A3Q2NNA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.

8078:LOC105921095
gene id: 8078:LOC105921095
uniprot id: A0A146NSL0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

8078:slc43a3b
gene id: 8078:slc43a3b
uniprot id: A0A3Q2PJ17
names: Subcellular Location Annotation
messages: Membrane

8078:g6pc3
gene id: 8078:g6pc3
uniprot id: A0A146ZZE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8078:tmco3
gene id: 8078:tmco3
uniprot id: A0A3Q2QIS8
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105936186
gene id: 8078:LOC105936186
uniprot id: A0A146ZRF3
names: Subcellular Location Annotation
messages: Membrane

8078:asf1bb
gene id: 8078:asf1bb
uniprot id: A0A146QPL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

8078:LOC105937306
gene id: 8078:LOC105937306
uniprot id: A0A146NLM5
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:rab4b
gene id: 8078:rab4b
uniprot id: A0A3Q2QUX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

8078:pdrg1
gene id: 8078:pdrg1
uniprot id: A0A3Q2QXQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

8078:nsun6
gene id: 8078:nsun6
uniprot id: A0A3Q2UGV7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:foxo6b
gene id: 8078:foxo6b
uniprot id: A0A3Q2Q644
names: Subcellular Location Annotation
messages: Nucleus

8078:ap1m3
gene id: 8078:ap1m3
uniprot id: A0A3Q2NP48
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

8078:rbl2
gene id: 8078:rbl2
uniprot id: A0A3Q2QYB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

8078:cdk5r1b
gene id: 8078:cdk5r1b
uniprot id: A0A3Q2QBV6
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

8078:panx3
gene id: 8078:panx3
uniprot id: A0A3Q2NV82
uniprot id: A0A3Q2NV88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8078:csf1ra
gene id: 8078:csf1ra
uniprot id: A0A3Q2TBM6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:LOC105920531
gene id: 8078:LOC105920531
uniprot id: A0A3Q2QM03
names: Similarity
messages: Belongs to the ANP32 family.

8078:tlcd5a
gene id: 8078:tlcd5a
uniprot id: A0A146P3L9
names: Subcellular Location Annotation
messages: Membrane

8078:cth1
gene id: 8078:cth1
uniprot id: A0A3Q2Q424
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8078:alg11
gene id: 8078:alg11
uniprot id: A0A3Q2PZI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

8078:canx
gene id: 8078:canx
uniprot id: A0A3Q2P1L0
names: Similarity
messages: Belongs to the calreticulin family.

8078:rnd3a
gene id: 8078:rnd3a
uniprot id: A0A3Q2QYC2
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

8078:pmp22b
gene id: 8078:pmp22b
uniprot id: A0A146NMF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

8078:LOC105927989
gene id: 8078:LOC105927989
uniprot id: A0A147A7E4
names: Similarity
messages: Belongs to the copine family.

8078:gcnt3
gene id: 8078:gcnt3
uniprot id: A0A146Q1A9
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8078:arhgef28a
gene id: 8078:arhgef28a
uniprot id: A0A146Z052
names: Subcellular Location Annotation
messages: Cytoplasm

8078:tubg1
gene id: 8078:tubg1
uniprot id: A0A147B104
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.
messages: centrosome

8078:pfdn5
gene id: 8078:pfdn5
uniprot id: A0A3Q2PH74
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

8078:LOC105933072
gene id: 8078:LOC105933072
uniprot id: A0A3Q2R1M5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8078:dhdds
gene id: 8078:dhdds
uniprot id: A0A3Q2UL19
names: Similarity
messages: Belongs to the UPP synthase family.

8078:ppargc1a
gene id: 8078:ppargc1a
uniprot id: A0A3Q2UPT7
names: Subcellular Location Annotation
messages: PML body

8078:lbx2
gene id: 8078:lbx2
uniprot id: A0A146ZZP5
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105939056
gene id: 8078:LOC105939056
uniprot id: A0A3Q2U823
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8078:polr2c
gene id: 8078:polr2c
uniprot id: A0A147A554
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

8078:LOC105915406
gene id: 8078:LOC105915406
uniprot id: A0A3Q2PB24
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8078:casp7
gene id: 8078:casp7
uniprot id: A0A3Q2T323
names: Similarity
messages: Belongs to the peptidase C14A family.

8078:fam20b
gene id: 8078:fam20b
uniprot id: A0A3Q2SN86
names: Similarity
messages: Belongs to the FAM20 family.

8078:g6pca.2
gene id: 8078:g6pca.2
uniprot id: A0A3Q2QL01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8078:ninj1
gene id: 8078:ninj1
uniprot id: A0A3Q2P051
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

8078:rorca
gene id: 8078:rorca
uniprot id: A0A3Q2NPQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:atp5pf
gene id: 8078:atp5pf
uniprot id: A0A3Q2PXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion inner membrane

8078:dlg5a
gene id: 8078:dlg5a
uniprot id: A0A3Q2PZM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cytoplasm

8078:gmfg
gene id: 8078:gmfg
uniprot id: A0A3Q2Q8J7
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

8078:tsc22d3
gene id: 8078:tsc22d3
uniprot id: A0A3Q2NSQ7
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

8078:usta
gene id: 8078:usta
uniprot id: A0A3Q2NN19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

8078:LOC105934100
gene id: 8078:LOC105934100
uniprot id: A0A146ZVE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

8078:LOC105927400
gene id: 8078:LOC105927400
uniprot id: F6KV77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

8078:cryabb
gene id: 8078:cryabb
uniprot id: A0A3Q2QTJ3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8078:med22
gene id: 8078:med22
uniprot id: A0A3Q2QYE5
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8078:LOC105919840
gene id: 8078:LOC105919840
uniprot id: A0A3Q2UJT2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8078:igf2bp3
gene id: 8078:igf2bp3
uniprot id: A0A3Q2PM28
names: Similarity
messages: Belongs to the RRM IMP/VICKZ family.

8078:nop14
gene id: 8078:nop14
uniprot id: A0A3Q2U135
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

8078:LOC105919889
gene id: 8078:LOC105919889
uniprot id: A0A3Q2UI04
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

8078:plagl2
gene id: 8078:plagl2
uniprot id: A0A3Q2T819
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

8078:sema4e
gene id: 8078:sema4e
uniprot id: A0A3Q2SQ77
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:tgfa
gene id: 8078:tgfa
uniprot id: A0A3Q2TCP0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:inpp5d
gene id: 8078:inpp5d
uniprot id: A0A3Q2P8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

8078:LOC105936238
gene id: 8078:LOC105936238
uniprot id: A0A146NN81
names: Similarity
messages: Belongs to the BZW family.

8078:atp5l
gene id: 8078:atp5l
uniprot id: A0A3Q2PSL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

8078:gmpr
gene id: 8078:gmpr
uniprot id: A0A3Q2TMH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

8078:dolk
gene id: 8078:dolk
uniprot id: A0A3Q2P640
names: Similarity
messages: Belongs to the polyprenol kinase family.

8078:ankha
gene id: 8078:ankha
uniprot id: A0A3Q2PBV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

8078:arpc4l
gene id: 8078:arpc4l
uniprot id: A0A3Q2P008
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

8078:kmt5ab
gene id: 8078:kmt5ab
uniprot id: A0A3Q2PQL6
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8078:LOC105929480
gene id: 8078:LOC105929480
uniprot id: A0A3Q2Q474
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

8078:LOC105938174
gene id: 8078:LOC105938174
uniprot id: A0A3Q2Q1T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

8078:smarcal1
gene id: 8078:smarcal1
uniprot id: A0A3Q2QFK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
messages: Nucleus

8078:osbpl9
gene id: 8078:osbpl9
uniprot id: A0A146NMX0
uniprot id: A0A3Q2Q9K0
names: Similarity
messages: Belongs to the OSBP family.

8078:LOC105925574
gene id: 8078:LOC105925574
uniprot id: A0A3Q2Q245
names: Similarity
messages: Belongs to the ependymin family.

8078:cog7
gene id: 8078:cog7
uniprot id: A0A3Q2NQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:LOC105932788
gene id: 8078:LOC105932788
uniprot id: A0A146YZS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8078:onecutl
gene id: 8078:onecutl
uniprot id: A0A3Q2QHD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8078:srpra
gene id: 8078:srpra
uniprot id: A0A3Q2PQR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane

8078:LOC105926939
gene id: 8078:LOC105926939
uniprot id: A0A3Q2UB70
names: Similarity
messages: Belongs to the peptidase M1 family.

8078:homer2
gene id: 8078:homer2
uniprot id: A0A146P4G0
uniprot id: A0A3Q2P0H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Postsynaptic density
messages: Synapse

8078:sfxn3
gene id: 8078:sfxn3
uniprot id: A0A146P6U0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

8078:LOC105925611
gene id: 8078:LOC105925611
uniprot id: A0A147AC23
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8078:dnmt3ab
gene id: 8078:dnmt3ab
uniprot id: A0A3Q2NP64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

8078:steap4
gene id: 8078:steap4
uniprot id: A0A3Q2TDB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

8078:LOC105937144
gene id: 8078:LOC105937144
uniprot id: A0A147AZK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8078:nipa1
gene id: 8078:nipa1
uniprot id: A0A3Q2QM91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8078:sulf2a
gene id: 8078:sulf2a
uniprot id: A0A146Z6H0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8078:pelp1
gene id: 8078:pelp1
uniprot id: A0A3Q2PJM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Cytoplasm
messages: Nucleus

8078:LOC105934828
gene id: 8078:LOC105934828
uniprot id: A0A3Q2QZ73
names: Subcellular Location Annotation
messages: extracellular space

8078:gnas
gene id: 8078:gnas
uniprot id: A0A3Q2Q5K4
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

8078:nr1i2
gene id: 8078:nr1i2
uniprot id: A6N8S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:LOC105938043
gene id: 8078:LOC105938043
uniprot id: A0A3Q2P074
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8078:nol12
gene id: 8078:nol12
uniprot id: A0A3Q2QBA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

8078:bpnt1
gene id: 8078:bpnt1
uniprot id: A0A3Q2PY84
uniprot id: A0A3Q2R1Q5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8078:dhrs3b
gene id: 8078:dhrs3b
uniprot id: A0A3Q2QKU8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:vps53
gene id: 8078:vps53
uniprot id: A0A3Q2TNM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

8078:rplp0
gene id: 8078:rplp0
uniprot id: A0A3Q2Q9C5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

8078:myom3
gene id: 8078:myom3
uniprot id: A0A3Q2PTK1
names: Subcellular Location Annotation
messages: Membrane

8078:cpa5
gene id: 8078:cpa5
uniprot id: A0A3Q2T4B7
names: Similarity
messages: Belongs to the peptidase M14 family.

8078:n4bp3
gene id: 8078:n4bp3
uniprot id: A0A3Q2P4S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Cytoplasmic vesicle
messages: Vesicle
messages: axon
messages: dendrite

8078:LOC105925492
gene id: 8078:LOC105925492
uniprot id: A0A3Q2QFM3
names: Similarity
messages: Belongs to the arrestin family.

8078:tmem183a
gene id: 8078:tmem183a
uniprot id: A0A3Q2R2I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

8078:rxrgb
gene id: 8078:rxrgb
uniprot id: A0A3Q2R498
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

8078:LOC105918723
gene id: 8078:LOC105918723
uniprot id: A0A3Q2QLZ0
names: Similarity
messages: Belongs to the NDRG family.

8078:pmch
gene id: 8078:pmch
uniprot id: A0A3Q2NTZ0
names: Function
messages: Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.

8078:exoc7
gene id: 8078:exoc7
uniprot id: A0A146X4F0
uniprot id: A0A3Q2PAB5
uniprot id: A0A3Q2PC11
uniprot id: A0A3Q2QL30
names: Function
names: Similarity
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

8078:tspan33a
gene id: 8078:tspan33a
uniprot id: A0A3Q2QY86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:slc4a1a
gene id: 8078:slc4a1a
uniprot id: A0A146VAG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

8078:LOC105933133
gene id: 8078:LOC105933133
uniprot id: A0A146W0H0
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.

8078:seta
gene id: 8078:seta
uniprot id: A0A3Q2PDY7
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

8078:LOC105932260
gene id: 8078:LOC105932260
uniprot id: A0A3Q2QDY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

8078:LOC105940216
gene id: 8078:LOC105940216
uniprot id: A0A146ZHY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Cell membrane
messages: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.
messages: Membrane
messages: Nucleus outer membrane

8078:rbm8a
gene id: 8078:rbm8a
uniprot id: A0A3Q2PGE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

8078:LOC105935648
gene id: 8078:LOC105935648
uniprot id: A0A3Q2SVM6
names: Subcellular Location Annotation
messages: Membrane

8078:dag1
gene id: 8078:dag1
uniprot id: A0A3Q2T857
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

8078:myclb
gene id: 8078:myclb
uniprot id: A0A3Q2R1I4
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

8078:dnajc22
gene id: 8078:dnajc22
uniprot id: A0A3Q2NMH7
names: Function
names: Subcellular Location Annotation
messages: May function as a co-chaperone.
messages: Membrane

8078:pdgfbb
gene id: 8078:pdgfbb
uniprot id: A0A3Q2QBK1
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8078:LOC105915826
gene id: 8078:LOC105915826
uniprot id: A0A3Q2PQY0
names: Subcellular Location Annotation
messages: Secreted

8078:LOC105936364
gene id: 8078:LOC105936364
uniprot id: A0A3Q2NST2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
messages: Membrane

8078:prss16
gene id: 8078:prss16
uniprot id: A0A3Q2Q0H7
names: Similarity
messages: Belongs to the peptidase S28 family.

8078:rps25
gene id: 8078:rps25
uniprot id: A0A146YRG3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

8078:pacc1
gene id: 8078:pacc1
uniprot id: A0A3Q2QLC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

8078:ireb2
gene id: 8078:ireb2
uniprot id: A0A3Q2QX11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Cytoplasm
messages: RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

8078:si:dkey-197c15.6
gene id: 8078:si:dkey-197c15.6
uniprot id: A0A3Q2Q6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

8078:acaa1
gene id: 8078:acaa1
uniprot id: A0A147AS21
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8078:LOC105923864
gene id: 8078:LOC105923864
uniprot id: A0A3Q2QP71
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8078:gstz1
gene id: 8078:gstz1
uniprot id: A0A3Q2QTR0
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

8078:stx7l
gene id: 8078:stx7l
uniprot id: A0A3Q2QZ58
names: Similarity
messages: Belongs to the syntaxin family.

8078:pno1
gene id: 8078:pno1
uniprot id: A0A3Q2QI41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNO1 family.
messages: nucleolus

8078:hspb7
gene id: 8078:hspb7
uniprot id: A0A3Q2PF85
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8078:cdc42se2
gene id: 8078:cdc42se2
uniprot id: A0A3Q2QG54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

8078:glrx
gene id: 8078:glrx
uniprot id: A0A3Q2UQW5
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

8078:LOC105933535
gene id: 8078:LOC105933535
uniprot id: A0A146P7J7
names: Caution
names: Similarity
messages: Belongs to the Ntn-hydrolase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:mrpl37
gene id: 8078:mrpl37
uniprot id: A0A3Q2QD96
names: Subcellular Location Annotation
messages: Mitochondrion

8078:cpox
gene id: 8078:cpox
uniprot id: A0A3Q2P2G1
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

8078:dao.2
gene id: 8078:dao.2
uniprot id: A0A3Q2TDY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

8078:foxb1a
gene id: 8078:foxb1a
uniprot id: A0A146S1D5
names: Subcellular Location Annotation
messages: Nucleus

8078:ppfibp1b
gene id: 8078:ppfibp1b
uniprot id: A0A3Q2QH54
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

8078:LOC105939953
gene id: 8078:LOC105939953
uniprot id: A0A146ZIH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein phosphatase inhibitor 1 family.
messages: Cytoplasm
messages: Inhibitor of protein-phosphatase 1.

8078:upf2
gene id: 8078:upf2
uniprot id: A0A3Q2QIP1
names: Subcellular Location Annotation
messages: Cytoplasm

8078:aqr
gene id: 8078:aqr
uniprot id: A0A3Q2PXV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWF11 family.
messages: Nucleus

8078:LOC105928863
gene id: 8078:LOC105928863
uniprot id: A0A3Q2Q3V7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

8078:cdip1
gene id: 8078:cdip1
uniprot id: A0A146P508
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

8078:snx19a
gene id: 8078:snx19a
uniprot id: A0A147A4U9
names: Similarity
messages: Belongs to the sorting nexin family.

8078:pik3cb
gene id: 8078:pik3cb
uniprot id: A0A3Q2UNI5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8078:LOC105920817
gene id: 8078:LOC105920817
uniprot id: A0A3Q2NZI9
names: Similarity
messages: Belongs to the KHDC4 family.

8078:atxn1l
gene id: 8078:atxn1l
uniprot id: A0A146ZIF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

8078:LOC105923746
gene id: 8078:LOC105923746
uniprot id: A0A3Q2QH14
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

8078:scamp4
gene id: 8078:scamp4
uniprot id: A0A146ZYS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8078:ficd
gene id: 8078:ficd
uniprot id: A0A3Q2TEN5
names: Similarity
messages: Belongs to the fic family.

8078:efnb1
gene id: 8078:efnb1
uniprot id: A0A3Q2NQL9
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:tbxta
gene id: 8078:tbxta
uniprot id: A0A3Q2NYC2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:spns3
gene id: 8078:spns3
uniprot id: A0A3Q2PNF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

8078:ecsit
gene id: 8078:ecsit
uniprot id: A0A146YPK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ECSIT family.
messages: Cytoplasm
messages: Mitochondrion
messages: Nucleus

8078:coq7
gene id: 8078:coq7
uniprot id: A0A146WBC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

8078:c14h20orf27
gene id: 8078:c14h20orf27
uniprot id: A0A146P6Z0
names: Similarity
messages: Belongs to the UPF0687 family.

8078:LOC105915428
gene id: 8078:LOC105915428
uniprot id: A0A3Q2P9A2
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8078:slc66a1
gene id: 8078:slc66a1
uniprot id: A0A3Q2QLJ7
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105936610
gene id: 8078:LOC105936610
uniprot id: A0A3Q2QLT4
names: Subcellular Location Annotation
messages: Membrane

8078:per2
gene id: 8078:per2
uniprot id: A0A3Q2P0E4
uniprot id: A0A3Q2QBF1
uniprot id: A0A3Q2U408
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8078:cntfr
gene id: 8078:cntfr
uniprot id: A0A3Q2QBZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.
messages: Membrane

8078:sh3bgrl3
gene id: 8078:sh3bgrl3
uniprot id: A0A3Q2Q9W3
names: Similarity
messages: Belongs to the SH3BGR family.

8078:prickle1b
gene id: 8078:prickle1b
uniprot id: A0A3Q2P348
uniprot id: A0A3Q2QFX8
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

8078:LOC105932799
gene id: 8078:LOC105932799
uniprot id: A0A3Q2UBW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

8078:anks1b
gene id: 8078:anks1b
uniprot id: A0A3Q2SV05
names: Subcellular Location Annotation
messages: Cytoplasm

8078:sgk3
gene id: 8078:sgk3
uniprot id: A0A3Q2NUF7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

8078:fkbp4
gene id: 8078:fkbp4
uniprot id: A0A3Q2NUQ9
names: Subcellular Location Annotation
messages: Mitochondrion
messages: cytoskeleton
messages: cytosol

8078:si:ch211-210c8.6
gene id: 8078:si:ch211-210c8.6
uniprot id: A0A3Q2P0Z4
names: Subcellular Location Annotation
messages: Membrane

8078:klhl40b
gene id: 8078:klhl40b
uniprot id: A0A146ZLM0
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

8078:cplx4c
gene id: 8078:cplx4c
uniprot id: A0A147A1J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8078:cd40lg
gene id: 8078:cd40lg
uniprot id: A0A147ABR9
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8078:oxct1a
gene id: 8078:oxct1a
uniprot id: A0A3Q2PTQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

8078:pax9
gene id: 8078:pax9
uniprot id: A0A3Q2TX04
uniprot id: A0A3Q2TX14
names: Subcellular Location Annotation
messages: Nucleus

8078:gtf2h3
gene id: 8078:gtf2h3
uniprot id: A0A146P6C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

8078:sbds
gene id: 8078:sbds
uniprot id: A0A3Q2PZU8
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

8078:aldh1a2
gene id: 8078:aldh1a2
uniprot id: A0A3Q2ULK8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8078:slco2a1
gene id: 8078:slco2a1
uniprot id: A0A146N573
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8078:sptlc3
gene id: 8078:sptlc3
uniprot id: A0A146UBA2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

8078:map2k2a
gene id: 8078:map2k2a
uniprot id: A0A3Q2PDS6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:LOC105931566
gene id: 8078:LOC105931566
uniprot id: A0A147B3B6
names: Similarity
messages: Belongs to the peptidase M10A family.

8078:ckmt1
gene id: 8078:ckmt1
uniprot id: A0A3Q2ULQ0
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8078:nme6
gene id: 8078:nme6
uniprot id: A0A3Q2QXN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8078:LOC105934270
gene id: 8078:LOC105934270
uniprot id: A0A3Q2PPK5
names: Similarity
messages: Belongs to the importin alpha family.

8078:zgc:86839
gene id: 8078:zgc:86839
uniprot id: A0A3Q2QAV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

8078:popdc2
gene id: 8078:popdc2
uniprot id: A0A146ZLR8
names: Similarity
messages: Belongs to the popeye family.

8078:tysnd1
gene id: 8078:tysnd1
uniprot id: A0A3Q2TT20
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

8078:si:ch73-12o23.1
gene id: 8078:si:ch73-12o23.1
uniprot id: A0A3Q2PXV4
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:peli1b
gene id: 8078:peli1b
uniprot id: A0A3Q2PCH0
names: Similarity
messages: Belongs to the pellino family.

8078:LOC105927784
gene id: 8078:LOC105927784
uniprot id: A0A3Q2NQT5
names: Similarity
messages: Belongs to the SNF7 family.

8078:zgc:110789
gene id: 8078:zgc:110789
uniprot id: A0A3Q2QDG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

8078:LOC105935590
gene id: 8078:LOC105935590
uniprot id: A0A146P4D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8078:dda1
gene id: 8078:dda1
uniprot id: A0A3Q2UQ72
names: Similarity
messages: Belongs to the DDA1 family.

8078:LOC105937381
gene id: 8078:LOC105937381
uniprot id: A0A3Q2NNJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

8078:tmcc1a
gene id: 8078:tmcc1a
uniprot id: A0A147B355
names: Similarity
messages: Belongs to the TEX28 family.

8078:abhd16a
gene id: 8078:abhd16a
uniprot id: A0A146NNZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. ABHD16 family.
messages: Membrane

8078:ca6
gene id: 8078:ca6
uniprot id: A0A146PJU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reversible hydration of carbon dioxide. Its role in saliva is unknown.
messages: Secreted

8078:asic1b
gene id: 8078:asic1b
uniprot id: A0A3Q2QDU5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:tmem106c
gene id: 8078:tmem106c
uniprot id: A0A3Q2QSD7
names: Similarity
messages: Belongs to the TMEM106 family.

8078:irf2bp2a
gene id: 8078:irf2bp2a
uniprot id: A0A147ATN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

8078:ror1
gene id: 8078:ror1
uniprot id: A0A3Q2NNY7
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:rpap2
gene id: 8078:rpap2
uniprot id: A0A147AQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.

8078:rrn3
gene id: 8078:rrn3
uniprot id: A0A3Q2QID6
names: Similarity
messages: Belongs to the RRN3 family.

8078:slc20a2
gene id: 8078:slc20a2
uniprot id: A0A3Q2NYS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

8078:LOC105938938
gene id: 8078:LOC105938938
uniprot id: A0A146V2L0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:sfpq
gene id: 8078:sfpq
uniprot id: A0A3Q2QQT1
names: Subcellular Location Annotation
messages: Nucleus speckle

8078:tubb4bl
gene id: 8078:tubb4bl
uniprot id: A0A147A0B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8078:LOC105928529
gene id: 8078:LOC105928529
uniprot id: A0A3Q2PTP9
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

8078:chmp5a
gene id: 8078:chmp5a
uniprot id: A0A3Q2QU44
names: Similarity
messages: Belongs to the SNF7 family.

8078:smdt1b
gene id: 8078:smdt1b
uniprot id: A0A3Q2P3F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

8078:sugp1
gene id: 8078:sugp1
uniprot id: A0A3Q2Q7N8
names: Subcellular Location Annotation
messages: Nucleus

8078:panx2
gene id: 8078:panx2
uniprot id: A0A3Q2PDM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8078:wbp4
gene id: 8078:wbp4
uniprot id: A0A3Q2PUJ6
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105917711
gene id: 8078:LOC105917711
uniprot id: A0A147AV73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8078:ppdpfb
gene id: 8078:ppdpfb
uniprot id: A0A3Q2TFF4
names: Similarity
messages: Belongs to the PPDPF family.

8078:LOC105938152
gene id: 8078:LOC105938152
uniprot id: A0A3Q2PZT1
names: Similarity
messages: Belongs to the CFAP157 family.

8078:six7
gene id: 8078:six7
uniprot id: A0A146RP65
names: Subcellular Location Annotation
messages: Nucleus

8078:smc1a
gene id: 8078:smc1a
uniprot id: A0A3Q2SMY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

8078:LOC105925761
gene id: 8078:LOC105925761
uniprot id: A0A3Q2PG26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

8078:LOC105931139
gene id: 8078:LOC105931139
uniprot id: A0A146ZYW2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8078:ftsj1
gene id: 8078:ftsj1
uniprot id: A0A3Q2T1E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

8078:dldh
gene id: 8078:dldh
uniprot id: A0A3Q2QIQ9
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

8078:LOC105917291
gene id: 8078:LOC105917291
uniprot id: A0A3Q2PRD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

8078:eif4ebp3l
gene id: 8078:eif4ebp3l
uniprot id: A0A3Q2NQ80
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

8078:mapk9
gene id: 8078:mapk9
uniprot id: A0A3Q2QNL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

8078:mettl14
gene id: 8078:mettl14
uniprot id: A0A146ZR94
names: Similarity
messages: Belongs to the MT-A70-like family.

8078:ier3ip1
gene id: 8078:ier3ip1
uniprot id: A0A3Q2QCY9
names: Similarity
messages: Belongs to the YOS1 family.

8078:mrps11
gene id: 8078:mrps11
uniprot id: A0A3Q2NNR7
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

8078:LOC105940102
gene id: 8078:LOC105940102
uniprot id: A0A3Q2P714
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

8078:abcc1
gene id: 8078:abcc1
uniprot id: A0A3Q2T472
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

8078:gna12a
gene id: 8078:gna12a
uniprot id: A0A3Q2Q6W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

8078:ube2g1a
gene id: 8078:ube2g1a
uniprot id: A0A146NPQ7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:acsf3
gene id: 8078:acsf3
uniprot id: A0A146S230
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8078:polr2h
gene id: 8078:polr2h
uniprot id: A0A3Q2QVB9
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

8078:LOC105931188
gene id: 8078:LOC105931188
uniprot id: A0A3Q2QA13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

8078:LOC105926654
gene id: 8078:LOC105926654
uniprot id: A0A3Q2NRD6
names: Subcellular Location Annotation
messages: Membrane

8078:si:dkey-185m8.2
gene id: 8078:si:dkey-185m8.2
uniprot id: A0A3Q2PXC4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8078:LOC105931069
gene id: 8078:LOC105931069
uniprot id: A0A147A2G7
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

8078:lef1
gene id: 8078:lef1
uniprot id: A0A3Q2P2G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8078:cables1
gene id: 8078:cables1
uniprot id: A0A3Q2P567
uniprot id: A0A3Q2P575
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

8078:LOC105928230
gene id: 8078:LOC105928230
uniprot id: A0A3Q2PBR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

8078:polr3f
gene id: 8078:polr3f
uniprot id: A0A3Q2QCS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

8078:mgmt
gene id: 8078:mgmt
uniprot id: A0A147A8Q4
names: Similarity
messages: Belongs to the MGMT family.

8078:LOC105940168
gene id: 8078:LOC105940168
uniprot id: A0A146SN76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

8078:sdhaf3
gene id: 8078:sdhaf3
uniprot id: A0A3Q2PSC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

8078:dph5
gene id: 8078:dph5
uniprot id: A0A3Q2NRW7
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

8078:ptn
gene id: 8078:ptn
uniprot id: A0A3Q2T922
names: Similarity
messages: Belongs to the pleiotrophin family.

8078:calr3b
gene id: 8078:calr3b
uniprot id: A0A3Q2QIT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

8078:LOC105928034
gene id: 8078:LOC105928034
uniprot id: A0A3Q2TF20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:LOC105938253
gene id: 8078:LOC105938253
uniprot id: A0A3Q2QZD0
names: Function
messages: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

8078:LOC105939524
gene id: 8078:LOC105939524
uniprot id: A0A146UYM7
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8078:lum
gene id: 8078:lum
uniprot id: A0A3Q2NW18
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to laminin.
messages: extracellular matrix

8078:LOC105940210
gene id: 8078:LOC105940210
uniprot id: A0A3Q2NR58
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8078:LOC105926766
gene id: 8078:LOC105926766
uniprot id: A0A3Q2Q1F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC43A transporter (TC 2.A.1.44) family.
messages: Membrane

8078:zgc:63587
gene id: 8078:zgc:63587
uniprot id: A0A3Q2PSV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

8078:ints10
gene id: 8078:ints10
uniprot id: A0A146ZIQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

8078:otc
gene id: 8078:otc
uniprot id: A0A147A9A6
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

8078:slc16a1a
gene id: 8078:slc16a1a
uniprot id: A0A146WVH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

8078:pcsk7
gene id: 8078:pcsk7
uniprot id: A0A3Q2QST9
names: Similarity
messages: Belongs to the peptidase S8 family.

8078:irf2
gene id: 8078:irf2
uniprot id: A0A3Q2P025
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:mmp9
gene id: 8078:mmp9
uniprot id: A0A146ZZU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: extracellular matrix

8078:ifi30
gene id: 8078:ifi30
uniprot id: A0A3Q2QBN1
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

8078:fbxl5
gene id: 8078:fbxl5
uniprot id: A0A3Q2PG58
names: Subcellular Location Annotation
messages: perinuclear region

8078:ptger4b
gene id: 8078:ptger4b
uniprot id: A0A146PMJ0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

8078:sh3bp4a
gene id: 8078:sh3bp4a
uniprot id: A0A147AY60
names: Subcellular Location Annotation
messages: Nucleus
messages: Vesicle
messages: clathrin-coated pit
messages: clathrin-coated vesicle

8078:saraf
gene id: 8078:saraf
uniprot id: A0A3Q2Q8F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:tmpob
gene id: 8078:tmpob
uniprot id: A0A3Q2QEQ9
names: Similarity
messages: Belongs to the LEM family.

8078:tmem201
gene id: 8078:tmem201
uniprot id: A0A147AYF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

8078:dclre1b
gene id: 8078:dclre1b
uniprot id: A0A3Q2SUZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

8078:psma1
gene id: 8078:psma1
uniprot id: A0A147ABE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8078:atl1
gene id: 8078:atl1
uniprot id: A0A3Q2NU81
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

8078:LOC105915653
gene id: 8078:LOC105915653
uniprot id: A0A3Q2TS18
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:dnmt1
gene id: 8078:dnmt1
uniprot id: A0A3Q2NPG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

8078:bmp16
gene id: 8078:bmp16
uniprot id: A0A3Q2P232
names: Similarity
messages: Belongs to the TGF-beta family.

8078:fgd5a
gene id: 8078:fgd5a
uniprot id: A0A3Q2NXM5
names: Subcellular Location Annotation
messages: cytoskeleton

8078:atp6v1c1b
gene id: 8078:atp6v1c1b
uniprot id: A0A3Q2TAP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

8078:mon1a
gene id: 8078:mon1a
uniprot id: A0A3Q2TNA6
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

8078:patl1
gene id: 8078:patl1
uniprot id: A0A3Q2PR29
names: Similarity
messages: Belongs to the PAT1 family.

8078:gucy1a1
gene id: 8078:gucy1a1
uniprot id: A0A147B0V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

8078:afg1lb
gene id: 8078:afg1lb
uniprot id: A0A3Q2SN38
names: Similarity
messages: Belongs to the AFG1 ATPase family.

8078:oplah
gene id: 8078:oplah
uniprot id: A0A3Q2NVC4
names: Similarity
messages: Belongs to the oxoprolinase family.

8078:bloc1s6
gene id: 8078:bloc1s6
uniprot id: A0A146ZRY1
names: Function
names: Similarity
messages: Belongs to the BLOC1S6 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

8078:LOC105935626
gene id: 8078:LOC105935626
uniprot id: A0A3Q2U4I7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

8078:map2k1
gene id: 8078:map2k1
uniprot id: A0A146YL43
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:LOC105917820
gene id: 8078:LOC105917820
uniprot id: A0A3Q2P0N5
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

8078:ddx20
gene id: 8078:ddx20
uniprot id: A0A3Q2PXE2
names: Similarity
messages: Belongs to the DEAD box helicase family.

8078:ppardb
gene id: 8078:ppardb
uniprot id: A0A147A0T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:sfr1
gene id: 8078:sfr1
uniprot id: A0A3Q2SQB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

8078:fkbp6
gene id: 8078:fkbp6
uniprot id: A0A3Q2Q030
names: Function
names: Similarity
messages: Belongs to the FKBP6 family.
messages: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

8078:rab14l
gene id: 8078:rab14l
uniprot id: A0A146WBA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

8078:kcnb2
gene id: 8078:kcnb2
uniprot id: A0A146P426
names: Subcellular Location Annotation
messages: Membrane
messages: Perikaryon

8078:cog4
gene id: 8078:cog4
uniprot id: A0A146P578
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

8078:vangl1
gene id: 8078:vangl1
uniprot id: A0A3Q2QPC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8078:LOC105918091
gene id: 8078:LOC105918091
uniprot id: A0A147AVL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8078:eya4
gene id: 8078:eya4
uniprot id: A0A3Q2QWL3
uniprot id: A0A3Q2TKQ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Nucleus

8078:psmc3
gene id: 8078:psmc3
uniprot id: A0A146ZKE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

8078:LOC105930723
gene id: 8078:LOC105930723
uniprot id: A0A3Q2UNZ2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8078:crebl2
gene id: 8078:crebl2
uniprot id: A0A3Q2PBT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

8078:gpd2
gene id: 8078:gpd2
uniprot id: A0A3Q2PQH9
uniprot id: A0A3Q2QSZ4
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

8078:unc119.1
gene id: 8078:unc119.1
uniprot id: A0A3Q2Q3F2
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8078:galnt6
gene id: 8078:galnt6
uniprot id: A0A147A5G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8078:timm8b
gene id: 8078:timm8b
uniprot id: A0A3Q2NN76
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8078:fas
gene id: 8078:fas
uniprot id: A0A3Q2TYD0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105915460
gene id: 8078:LOC105915460
uniprot id: A0A3Q2QG32
names: Similarity
messages: Belongs to the RCAN family.

8078:lzts2a
gene id: 8078:lzts2a
uniprot id: A0A146ZL16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LZTS2 family.
messages: Cytoplasm
messages: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
messages: centrosome

8078:LOC105928041
gene id: 8078:LOC105928041
uniprot id: A0A3Q2UJJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

8078:zdhhc5a
gene id: 8078:zdhhc5a
uniprot id: A0A3Q2QQD7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8078:LOC105940178
gene id: 8078:LOC105940178
uniprot id: A0A3Q2NST1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:nat9
gene id: 8078:nat9
uniprot id: A0A3Q2QJ55
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

8078:cryba2b
gene id: 8078:cryba2b
uniprot id: A0A146ZQZ1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8078:LOC105919179
gene id: 8078:LOC105919179
uniprot id: A0A146Y5A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8078:igsf8
gene id: 8078:igsf8
uniprot id: A0A3Q2PP98
names: Subcellular Location Annotation
messages: Membrane

8078:stat3
gene id: 8078:stat3
uniprot id: A0A3Q2QMS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8078:zgc:91890
gene id: 8078:zgc:91890
uniprot id: A0A3Q2QGQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

8078:sf3a3
gene id: 8078:sf3a3
uniprot id: A0A3Q2PW21
names: Similarity
messages: Belongs to the SF3A3 family.

8078:rpl31
gene id: 8078:rpl31
uniprot id: A0A3Q2QZW2
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

8078:mfap3l
gene id: 8078:mfap3l
uniprot id: A0A147B2T8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:btf3
gene id: 8078:btf3
uniprot id: A0A146YZZ3
names: Similarity
messages: Belongs to the NAC-beta family.

8078:atp8b1
gene id: 8078:atp8b1
uniprot id: A0A3Q2PDI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8078:rfng
gene id: 8078:rfng
uniprot id: A0A3Q2NUY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:fbxo25
gene id: 8078:fbxo25
uniprot id: A0A146WJ61
uniprot id: A0A146WLQ3
names: Subcellular Location Annotation
messages: Nucleus

8078:wnt16
gene id: 8078:wnt16
uniprot id: A0A3Q2QMY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8078:smarcad1a
gene id: 8078:smarcad1a
uniprot id: A0A146Z2W6
names: Subcellular Location Annotation
messages: Chromosome

8078:LOC105934444
gene id: 8078:LOC105934444
uniprot id: A0A3Q2P8M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8078:LOC105940043
gene id: 8078:LOC105940043
uniprot id: A0A3Q2QLP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

8078:cdh15
gene id: 8078:cdh15
uniprot id: A0A3Q2PT79
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8078:LOC105928056
gene id: 8078:LOC105928056
uniprot id: A0A3Q2QF54
names: Subcellular Location Annotation
messages: nucleoplasm

8078:LOC105939053
gene id: 8078:LOC105939053
uniprot id: A0A146PCC1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8078:txnrd3
gene id: 8078:txnrd3
uniprot id: A0A3Q2PNW1
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

8078:dync1i2a
gene id: 8078:dync1i2a
uniprot id: A0A3Q2QQ91
uniprot id: A0A3Q2UGU5
names: Similarity
messages: Belongs to the dynein intermediate chain family.

8078:kif26ab
gene id: 8078:kif26ab
uniprot id: A0A3Q2PNX8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8078:rab3ab
gene id: 8078:rab3ab
uniprot id: A0A3Q2QT84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

8078:dapk2b
gene id: 8078:dapk2b
uniprot id: A0A3Q2NQ15
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:xpo1a
gene id: 8078:xpo1a
uniprot id: A0A3Q2NRC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

8078:ldlrb
gene id: 8078:ldlrb
uniprot id: A0A3Q2P3Y8
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:thoc5
gene id: 8078:thoc5
uniprot id: A0A3Q2QK71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

8078:LOC105919586
gene id: 8078:LOC105919586
uniprot id: A0A3Q2SU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

8078:prkaa2
gene id: 8078:prkaa2
uniprot id: A0A147A6B7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

8078:LOC105929365
gene id: 8078:LOC105929365
uniprot id: A0A146WK74
names: Similarity
messages: Belongs to the spectrin family.

8078:naga
gene id: 8078:naga
uniprot id: A0A146PAA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

8078:sox4a
gene id: 8078:sox4a
uniprot id: A0A3Q2PTB3
names: Subcellular Location Annotation
messages: Nucleus

8078:ptk2bb
gene id: 8078:ptk2bb
uniprot id: A0A3Q2PYM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

8078:rnf8
gene id: 8078:rnf8
uniprot id: A0A3Q2TW06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.
messages: E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF). H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also catalyzes the formation of 'Lys-48'-linked polyubiquitin chains, leading to degradation of substrate proteins. In addition to its function in damage signaling, also plays a role in higher-order chromatin structure by mediating extensive chromatin decondensation.
messages: Homodimer. Forms a E2-E3 ubiquitin ligase complex composed of the RNF8 homodimer and a E2 heterodimer of UBE2N and UBE2V2.
messages: Nucleus
messages: The FHA domain specifically recognizes and binds ATM-phosphorylated MDC1.

8078:si:ch73-335m24.2
gene id: 8078:si:ch73-335m24.2
uniprot id: A0A146P6R2
names: Similarity
messages: Belongs to the EVA1 family.

8078:LOC105938549
gene id: 8078:LOC105938549
uniprot id: A0A146V4N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8078:LOC105915575
gene id: 8078:LOC105915575
uniprot id: A0A146PGJ6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8078:spon2b
gene id: 8078:spon2b
uniprot id: A0A147B4E2
names: Subcellular Location Annotation
messages: extracellular matrix

8078:ptges3b
gene id: 8078:ptges3b
uniprot id: A0A3Q2QWS0
names: Similarity
messages: Belongs to the p23/wos2 family.

8078:zgc:162707
gene id: 8078:zgc:162707
uniprot id: A0A146P4H2
names: Similarity
messages: Belongs to the UPF0524 family.

8078:slc25a24
gene id: 8078:slc25a24
uniprot id: A0A3Q2TZU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8078:sh3rf2
gene id: 8078:sh3rf2
uniprot id: A0A3Q2UBZ2
names: Similarity
messages: Belongs to the SH3RF family.

8078:adam19b
gene id: 8078:adam19b
uniprot id: A0A3Q2U5Y7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105937385
gene id: 8078:LOC105937385
uniprot id: A0A3Q2P1B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

8078:idh1
gene id: 8078:idh1
uniprot id: A0A3Q2Q584
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

8078:LOC105929926
gene id: 8078:LOC105929926
uniprot id: A0A3Q2T452
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8078:pex5
gene id: 8078:pex5
uniprot id: A0A3Q2QL05
uniprot id: A0A3Q2QLL9
uniprot id: A0A3Q2UCT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
messages: Cytoplasm
messages: Membrane

8078:prpf3
gene id: 8078:prpf3
uniprot id: A0A146P611
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

8078:eif6
gene id: 8078:eif6
uniprot id: A0A3Q2PSI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

8078:ap1g2
gene id: 8078:ap1g2
uniprot id: A0A147A2R4
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8078:ntn1b
gene id: 8078:ntn1b
uniprot id: A0A146WJ15
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105940286
gene id: 8078:LOC105940286
uniprot id: A0A146UUW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

8078:sec11a
gene id: 8078:sec11a
uniprot id: A0A3Q2PE49
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:LOC105938925
gene id: 8078:LOC105938925
uniprot id: A0A3Q2QQT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

8078:LOC105938449
gene id: 8078:LOC105938449
uniprot id: A0A3Q2PE02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8078:grm8a
gene id: 8078:grm8a
uniprot id: A0A3Q2QHH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8078:LOC105937123
gene id: 8078:LOC105937123
uniprot id: A0A3Q2QJ51
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8078:LOC105939781
gene id: 8078:LOC105939781
uniprot id: A0A3Q2Q8B1
names: Similarity
messages: Belongs to the MS4A family.

8078:bnip1b
gene id: 8078:bnip1b
uniprot id: A0A3Q2PYT8
names: Subcellular Location Annotation
messages: Membrane

8078:zeb1b
gene id: 8078:zeb1b
uniprot id: A0A3Q2P3J3
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

8078:dgcr6
gene id: 8078:dgcr6
uniprot id: A0A146N0F3
names: Similarity
messages: Belongs to the gonadal family.

8078:cstf1
gene id: 8078:cstf1
uniprot id: A0A3Q2QVH1
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105918964
gene id: 8078:LOC105918964
uniprot id: A0A147ATM2
names: Similarity
messages: Belongs to the NDRG family.

8078:cmtm4
gene id: 8078:cmtm4
uniprot id: A0A3Q2TJK3
names: Subcellular Location Annotation
messages: Membrane

8078:dis3l2
gene id: 8078:dis3l2
uniprot id: A0A3Q2QXN8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

8078:pik3ip1
gene id: 8078:pik3ip1
uniprot id: A0A3Q2QRT1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:bnip3lb
gene id: 8078:bnip3lb
uniprot id: A0A3Q2TD15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

8078:slc35e1
gene id: 8078:slc35e1
uniprot id: A0A3Q2PPR8
names: Subcellular Location Annotation
messages: Membrane

8078:trpc6a
gene id: 8078:trpc6a
uniprot id: A0A147AR03
names: Subcellular Location Annotation
messages: Membrane

8078:rarga
gene id: 8078:rarga
uniprot id: A0A146WQB1
uniprot id: A0A3Q2NMK4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8078:LOC105916922
gene id: 8078:LOC105916922
uniprot id: A0A3Q2TE46
names: Similarity
messages: Belongs to the DEAD box helicase family.

8078:chrna2b
gene id: 8078:chrna2b
uniprot id: A0A3Q2QYX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8078:c2h11orf58
gene id: 8078:c2h11orf58
uniprot id: A0A3Q2QXX9
names: Similarity
messages: Belongs to the SMAP family.

8078:pou6f1
gene id: 8078:pou6f1
uniprot id: A0A146ZU48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8078:LOC105919629
gene id: 8078:LOC105919629
uniprot id: A0A146NY35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8078:mchr1a
gene id: 8078:mchr1a
uniprot id: A0A3Q2QAA4
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

8078:tspan5a
gene id: 8078:tspan5a
uniprot id: A0A146YWU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:npc1
gene id: 8078:npc1
uniprot id: A0A3Q2P4X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

8078:ccr9b
gene id: 8078:ccr9b
uniprot id: A0A146P796
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:isoc2
gene id: 8078:isoc2
uniprot id: A0A146ZTH0
names: Similarity
messages: Belongs to the isochorismatase family.

8078:LOC105936358
gene id: 8078:LOC105936358
uniprot id: A0A146ZR40
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

8078:tm9sf3
gene id: 8078:tm9sf3
uniprot id: A0A146NE05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

8078:polr2j
gene id: 8078:polr2j
uniprot id: A0A3Q2P123
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

8078:igsf3
gene id: 8078:igsf3
uniprot id: A0A3Q2TK26
names: Subcellular Location Annotation
messages: Membrane

8078:inka2
gene id: 8078:inka2
uniprot id: A0A3Q2PNU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

8078:LOC105923210
gene id: 8078:LOC105923210
uniprot id: A0A147B3Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

8078:cpxm2
gene id: 8078:cpxm2
uniprot id: A0A3Q2T6C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

8078:LOC105935579
gene id: 8078:LOC105935579
uniprot id: A0A146ZTD8
names: Subcellular Location Annotation
messages: Membrane

8078:cnrip1a
gene id: 8078:cnrip1a
uniprot id: A0A3Q2QPH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

8078:tmed7
gene id: 8078:tmed7
uniprot id: A0A3Q2Q2I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

8078:LOC105935197
gene id: 8078:LOC105935197
uniprot id: A0A146ZSX9
names: Similarity
messages: Belongs to the peptidase M10A family.

8078:trpc4b
gene id: 8078:trpc4b
uniprot id: A0A146ZMF2
names: Subcellular Location Annotation
messages: Membrane

8078:pglyrp2
gene id: 8078:pglyrp2
uniprot id: A0A3Q2Q7Z2
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

8078:LOC105926394
gene id: 8078:LOC105926394
uniprot id: A0A3Q2PPS0
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105919116
gene id: 8078:LOC105919116
uniprot id: A0A3Q2TVK0
names: Subcellular Location Annotation
messages: extracellular space

8078:retsat
gene id: 8078:retsat
uniprot id: A0A3Q2PDR7
names: Similarity
messages: Belongs to the Rab GDI family.

8078:zgc:114130
gene id: 8078:zgc:114130
uniprot id: A0A3Q2TAS1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8078:LOC105932877
gene id: 8078:LOC105932877
uniprot id: A0A146ZXV6
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

8078:ctsh
gene id: 8078:ctsh
uniprot id: Q6XPZ8
names: Similarity
messages: Belongs to the peptidase C1 family.

8078:bud13
gene id: 8078:bud13
uniprot id: A0A146Y227
names: Similarity
messages: Belongs to the CWC26 family.

8078:zic1
gene id: 8078:zic1
uniprot id: A0A147AUC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

8078:tppp3
gene id: 8078:tppp3
uniprot id: A0A147ASF9
names: Similarity
messages: Belongs to the TPPP family.

8078:slc43a2b
gene id: 8078:slc43a2b
uniprot id: A0A3Q2PRI6
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105930140
gene id: 8078:LOC105930140
uniprot id: A0A147A2Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8078:spcs1
gene id: 8078:spcs1
uniprot id: A0A3Q2TQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:eloa
gene id: 8078:eloa
uniprot id: A0A3Q2QSY0
names: Subcellular Location Annotation
messages: Nucleus

8078:suz12b
gene id: 8078:suz12b
uniprot id: A0A147AQ98
uniprot id: A0A3Q2QC77
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

8078:s100s
gene id: 8078:s100s
uniprot id: A0A3Q2PCU2
names: Similarity
messages: Belongs to the S-100 family.

8078:atf4b
gene id: 8078:atf4b
uniprot id: A0A3Q2QDC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

8078:s1pr4
gene id: 8078:s1pr4
uniprot id: A0A3Q2QDC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8078:tardbpl
gene id: 8078:tardbpl
uniprot id: A0A146VWA2
names: Subcellular Location Annotation
messages: Nucleus

8078:ccdc90b
gene id: 8078:ccdc90b
uniprot id: A0A3Q2NYX7
names: Similarity
messages: Belongs to the CCDC90 family.

8078:dkk2
gene id: 8078:dkk2
uniprot id: A0A147AV58
names: Similarity
messages: Belongs to the dickkopf family.

8078:naa10
gene id: 8078:naa10
uniprot id: A0A146WM94
uniprot id: A0A3Q2Q437
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

8078:LOC105933267
gene id: 8078:LOC105933267
uniprot id: A0A3Q2PHF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8078:tecrb
gene id: 8078:tecrb
uniprot id: A0A3Q2PC97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:LOC105926034
gene id: 8078:LOC105926034
uniprot id: A0A3Q2NWC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8078:arrdc1b
gene id: 8078:arrdc1b
uniprot id: A0A3Q2TEM5
names: Similarity
messages: Belongs to the arrestin family.

8078:slc25a47a
gene id: 8078:slc25a47a
uniprot id: A0A3Q2QYW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:eif3s6ip
gene id: 8078:eif3s6ip
uniprot id: A0A3Q2PUQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8078:eomesb
gene id: 8078:eomesb
uniprot id: A0A3Q2NWD8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:LOC105932478
gene id: 8078:LOC105932478
uniprot id: A0A3Q2R0S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:syne3
gene id: 8078:syne3
uniprot id: A0A3Q2Q6J4
names: Similarity
messages: Belongs to the nesprin family.

8078:LOC105915510
gene id: 8078:LOC105915510
uniprot id: A0A3Q2Q490
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105917323
gene id: 8078:LOC105917323
uniprot id: A0A3Q2R2B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

8078:LOC105934693
gene id: 8078:LOC105934693
uniprot id: A0A3Q2SP88
names: Similarity
messages: Belongs to the MELT/VEPH family.

8078:LOC105920356
gene id: 8078:LOC105920356
uniprot id: A0A3Q2QUF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105918758
gene id: 8078:LOC105918758
uniprot id: A0A3Q2PDT1
names: Subcellular Location Annotation
messages: Membrane

8078:nudt6
gene id: 8078:nudt6
uniprot id: A0A3Q2QUT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

8078:selenos
gene id: 8078:selenos
uniprot id: A0A3Q2PWB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein S family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:s100a10a
gene id: 8078:s100a10a
uniprot id: A0A3Q2QMS4
names: Similarity
messages: Belongs to the S-100 family.

8078:gda
gene id: 8078:gda
uniprot id: A0A147AAI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

8078:lbx1b
gene id: 8078:lbx1b
uniprot id: A0A3Q2Q6A3
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105926430
gene id: 8078:LOC105926430
uniprot id: A0A3Q2PAB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

8078:rrp7a
gene id: 8078:rrp7a
uniprot id: A0A3Q2NZT9
names: Similarity
messages: Belongs to the RRP7 family.

8078:cdc42
gene id: 8078:cdc42
uniprot id: A0A146Y9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

8078:LOC118556101
gene id: 8078:LOC118556101
uniprot id: A0A146P4L0
uniprot id: A0A146ZMI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Chromosome

8078:tsfm
gene id: 8078:tsfm
uniprot id: A0A3Q2TAB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

8078:serinc5
gene id: 8078:serinc5
uniprot id: A0A146P5L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Cell membrane
messages: Membrane

8078:arg2
gene id: 8078:arg2
uniprot id: A2Q011
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

8078:ltn1
gene id: 8078:ltn1
uniprot id: A0A3Q2PU65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

8078:vamp2
gene id: 8078:vamp2
uniprot id: A0A146ZYY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane
messages: synaptic vesicle membrane

8078:vps35l
gene id: 8078:vps35l
uniprot id: A0A3Q2QVS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS35L family.
messages: Endosome

8078:LOC105915261
gene id: 8078:LOC105915261
uniprot id: A0A3Q2U241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8078:vps18
gene id: 8078:vps18
uniprot id: A0A3Q2QYR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

8078:tardbp
gene id: 8078:tardbp
uniprot id: A0A3Q2QYC0
names: Subcellular Location Annotation
messages: Nucleus

8078:bcl2b
gene id: 8078:bcl2b
uniprot id: A0A3Q2PN77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

8078:gtf2h1
gene id: 8078:gtf2h1
uniprot id: A0A147AWI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

8078:LOC105939439
gene id: 8078:LOC105939439
uniprot id: A0A3Q2UGQ8
names: Similarity
messages: Belongs to the BTG family.

8078:dusp6
gene id: 8078:dusp6
uniprot id: A0A3Q2QHU6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8078:mapre2
gene id: 8078:mapre2
uniprot id: A0A3Q2QMV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

8078:gramd1c
gene id: 8078:gramd1c
uniprot id: A0A3Q2QUQ9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:LOC105931878
gene id: 8078:LOC105931878
uniprot id: A0A3Q2TQW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

f3
gene id: 8078:il17a/f3
uniprot id: A0A3Q2P2D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

8078:LOC105919236
gene id: 8078:LOC105919236
uniprot id: A0A3Q2PTN0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8078:dars1
gene id: 8078:dars1
uniprot id: A0A3Q2PCI2
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

8078:LOC105928030
gene id: 8078:LOC105928030
uniprot id: A0A3Q2QSY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:eno1b
gene id: 8078:eno1b
uniprot id: A0A146ZX16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

8078:sult4a1
gene id: 8078:sult4a1
uniprot id: A0A146YZV4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8078:mlf1
gene id: 8078:mlf1
uniprot id: A0A3Q2P159
uniprot id: A0A3Q2P1C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

8078:chst3b
gene id: 8078:chst3b
uniprot id: A0A146SJG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8078:hjv
gene id: 8078:hjv
uniprot id: A0A3Q2Q271
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

8078:LOC105929187
gene id: 8078:LOC105929187
uniprot id: B1PCG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:LOC105921684
gene id: 8078:LOC105921684
uniprot id: A0A3Q2PKW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: cytoskeleton

8078:wdfy2
gene id: 8078:wdfy2
uniprot id: A0A3Q2PMG4
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8078:il1fma
gene id: 8078:il1fma
uniprot id: A0A3Q2P9F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

8078:pptc7a
gene id: 8078:pptc7a
uniprot id: A0A3Q2NYG1
names: Similarity
messages: Belongs to the PP2C family.

8078:eva1c
gene id: 8078:eva1c
uniprot id: A0A146Z7V6
names: Similarity
messages: Belongs to the EVA1 family.

8078:mul1b
gene id: 8078:mul1b
uniprot id: A0A3Q2QEJ3
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105938734
gene id: 8078:LOC105938734
uniprot id: A0A3Q2U0P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

8078:irx5a
gene id: 8078:irx5a
uniprot id: A0A3Q2QDW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8078:apoc1
gene id: 8078:apoc1
uniprot id: A0A3Q2QLB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C1 family.
messages: Secreted

8078:ccng1
gene id: 8078:ccng1
uniprot id: A0A146NWC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin G subfamily.
messages: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
messages: Nucleus

8078:LOC105926699
gene id: 8078:LOC105926699
uniprot id: A0A3Q2Q7V5
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8078:LOC105928244
gene id: 8078:LOC105928244
uniprot id: A0A3Q2QM10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

8078:LOC105931054
gene id: 8078:LOC105931054
uniprot id: A0A3Q2T1V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

8078:unc93b1
gene id: 8078:unc93b1
uniprot id: A0A3Q2PH02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

8078:LOC105915657
gene id: 8078:LOC105915657
uniprot id: A0A146YSP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:gsdmeb
gene id: 8078:gsdmeb
uniprot id: A0A3Q2PMV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

8078:pknox2
gene id: 8078:pknox2
uniprot id: A0A3Q2NVD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8078:uroc1
gene id: 8078:uroc1
uniprot id: A0A3Q2P2P0
names: Similarity
messages: Belongs to the urocanase family.

8078:fdft1
gene id: 8078:fdft1
uniprot id: A0A146NR57
uniprot id: A0A3Q2NNH3
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

8078:olfml2ba
gene id: 8078:olfml2ba
uniprot id: A0A3Q2Q2T4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:mrps7
gene id: 8078:mrps7
uniprot id: A0A3Q2TZF8
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

8078:hexdc
gene id: 8078:hexdc
uniprot id: A0A3Q2UKG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

8078:tcp1
gene id: 8078:tcp1
uniprot id: A0A3Q2TVX0
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

8078:gdap1
gene id: 8078:gdap1
uniprot id: A0A146RSX9
names: Similarity
messages: Belongs to the GST superfamily.

8078:capzb
gene id: 8078:capzb
uniprot id: A0A146N3S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

8078:LOC105915898
gene id: 8078:LOC105915898
uniprot id: A0A3Q2PMA2
names: Similarity
messages: Belongs to the LCA5 family.

8078:wnt9b
gene id: 8078:wnt9b
uniprot id: A0A147B100
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8078:LOC105931242
gene id: 8078:LOC105931242
uniprot id: A0A3Q2Q8Q7
names: Similarity
messages: Belongs to the hexokinase family.

8078:rnf121
gene id: 8078:rnf121
uniprot id: A0A3Q2NRX1
names: Subcellular Location Annotation
messages: Membrane

8078:tpp1
gene id: 8078:tpp1
uniprot id: A0A3Q2P3I7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:erap2
gene id: 8078:erap2
uniprot id: A0A3Q2QJC4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8078:LOC105939538
gene id: 8078:LOC105939538
uniprot id: A0A3Q2UCZ0
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105937313
gene id: 8078:LOC105937313
uniprot id: A0A146VBL5
names: Similarity
messages: Belongs to the globin family.

8078:sugt1
gene id: 8078:sugt1
uniprot id: A0A3Q2PVT8
names: Similarity
messages: Belongs to the SGT1 family.

8078:LOC105937216
gene id: 8078:LOC105937216
uniprot id: A0A3Q2U4N1
names: Similarity
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.

8078:man1b1a
gene id: 8078:man1b1a
uniprot id: A0A146WYT4
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8078:mrm2
gene id: 8078:mrm2
uniprot id: A0A147ANF6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

8078:rpl15
gene id: 8078:rpl15
uniprot id: A0A3Q2QWR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

8078:esrra
gene id: 8078:esrra
uniprot id: A0A3Q2NZ75
uniprot id: Q2I6X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8078:LOC105920176
gene id: 8078:LOC105920176
uniprot id: A0A3Q2U436
names: Similarity
messages: Belongs to the peptidase C2 family.

8078:LOC105926764
gene id: 8078:LOC105926764
uniprot id: A0A147AAQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:kat6b
gene id: 8078:kat6b
uniprot id: A0A3Q2PD57
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

8078:LOC105934070
gene id: 8078:LOC105934070
uniprot id: A0A3Q2Q7Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:LOC105938234
gene id: 8078:LOC105938234
uniprot id: A0A146P4T4
names: Similarity
messages: Belongs to the filamin family.

8078:agrp
gene id: 8078:agrp
uniprot id: A0A3Q2QTB4
names: Subcellular Location Annotation
messages: Secreted

8078:ndufs4
gene id: 8078:ndufs4
uniprot id: A0A3Q2SWM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

8078:dbnlb
gene id: 8078:dbnlb
uniprot id: A0A3Q2PYP3
uniprot id: A0A3Q2QYZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: Synapse
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: cytoskeleton
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

8078:kcnk10b
gene id: 8078:kcnk10b
uniprot id: A0A3Q2NVN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8078:hibadha
gene id: 8078:hibadha
uniprot id: A0A3Q2QNP2
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

8078:rpia
gene id: 8078:rpia
uniprot id: A0A3Q2T0N7
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

8078:rabggta
gene id: 8078:rabggta
uniprot id: A0A3Q2NNA6
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.

8078:LOC105917426
gene id: 8078:LOC105917426
uniprot id: A0A3Q2PTG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8078:prl
gene id: 8078:prl
uniprot id: A0A3Q2PMS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

8078:LOC105927685
gene id: 8078:LOC105927685
uniprot id: A0A3Q2QHL3
names: Subcellular Location Annotation
messages: Membrane

8078:cfl1
gene id: 8078:cfl1
uniprot id: A0A3Q2PKJ8
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

8078:hlfa
gene id: 8078:hlfa
uniprot id: A0A3Q2U819
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

8078:zfpl1
gene id: 8078:zfpl1
uniprot id: A0A3Q2SWX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZFPL1 family.
messages: Membrane
messages: Required for cis-Golgi integrity and efficient ER to Golgi transport.
messages: The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.
messages: cis-Golgi network membrane

8078:LOC105932614
gene id: 8078:LOC105932614
uniprot id: A0A3Q2TCB0
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8078:srsf5a
gene id: 8078:srsf5a
uniprot id: A0A146ZXL3
names: Similarity
messages: Belongs to the splicing factor SR family.

8078:LOC105926958
gene id: 8078:LOC105926958
uniprot id: A0A3Q2QLM2
names: Similarity
messages: Belongs to the AAA ATPase family.

8078:erf
gene id: 8078:erf
uniprot id: A0A3Q2QEI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:immp1l
gene id: 8078:immp1l
uniprot id: A0A3Q2TPE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

8078:ptdss1a
gene id: 8078:ptdss1a
uniprot id: A0A3Q2TET5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:lpar2a
gene id: 8078:lpar2a
uniprot id: A0A3Q2QRR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

8078:vasnb
gene id: 8078:vasnb
uniprot id: A0A147B3N5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:prune
gene id: 8078:prune
uniprot id: A0A3Q2PGT7
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

8078:gmppaa
gene id: 8078:gmppaa
uniprot id: A0A146P434
uniprot id: A0A3Q2PAM4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

8078:rad23b
gene id: 8078:rad23b
uniprot id: A0A3Q2Q9V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

8078:LOC105935556
gene id: 8078:LOC105935556
uniprot id: A0A3Q2T405
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8078:cpt1ab
gene id: 8078:cpt1ab
uniprot id: A0A147AU53
uniprot id: A0A3Q2UB24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

8078:rpl7a
gene id: 8078:rpl7a
uniprot id: A0A3Q2SQG8
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

8078:mmd
gene id: 8078:mmd
uniprot id: A0A154MIE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8078:ndufaf3
gene id: 8078:ndufaf3
uniprot id: A0A3Q2QB76
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

8078:LOC105931056
gene id: 8078:LOC105931056
uniprot id: A0A3Q2U7V3
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

8078:zdhhc3a
gene id: 8078:zdhhc3a
uniprot id: A0A3Q2U7M7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8078:anxa6
gene id: 8078:anxa6
uniprot id: A0A147B5K3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

8078:ssr2
gene id: 8078:ssr2
uniprot id: A0A3Q2QV69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

8078:tradd
gene id: 8078:tradd
uniprot id: A0A3Q2UC33
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

8078:tbx20
gene id: 8078:tbx20
uniprot id: A0A3Q2UGH2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:cdc14b
gene id: 8078:cdc14b
uniprot id: A0A3Q2PSD3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

8078:slc12a9
gene id: 8078:slc12a9
uniprot id: A0A3Q2Q8R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

8078:men1
gene id: 8078:men1
uniprot id: A0A3Q2TVF8
names: Subcellular Location Annotation
messages: Nucleus

8078:cpe
gene id: 8078:cpe
uniprot id: A0A3Q2QHQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Membrane
messages: secretory vesicle membrane

8078:LOC105924023
gene id: 8078:LOC105924023
uniprot id: A0A3Q2NYA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8078:spire2
gene id: 8078:spire2
uniprot id: A0A3Q2PWQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

8078:LOC105930255
gene id: 8078:LOC105930255
uniprot id: A0A3Q2TLC6
names: Similarity
messages: Belongs to the chondromodulin-1 family.

8078:LOC105925805
gene id: 8078:LOC105925805
uniprot id: A0A146NRI0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:pou5f3
gene id: 8078:pou5f3
uniprot id: A0A146ZZD5
uniprot id: A0A3Q2PAT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8078:LOC105932949
gene id: 8078:LOC105932949
uniprot id: A0A146P6W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

8078:mdfic
gene id: 8078:mdfic
uniprot id: A0A3Q2NMI9
names: Similarity
messages: Belongs to the MDFI family.

8078:slc1a5
gene id: 8078:slc1a5
uniprot id: A0A3Q2PPR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8078:lsm14ab
gene id: 8078:lsm14ab
uniprot id: A0A3Q2R174
names: Similarity
messages: Belongs to the LSM14 family.

8078:ebag9
gene id: 8078:ebag9
uniprot id: A0A3Q2QHI9
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

8078:LOC105917682
gene id: 8078:LOC105917682
uniprot id: A0A3Q2QIY2
names: Subcellular Location Annotation
messages: Membrane

8078:shc1
gene id: 8078:shc1
uniprot id: A0A3Q2QZG4
names: Subcellular Location Annotation
messages: Cytoplasm

8078:lpcat3
gene id: 8078:lpcat3
uniprot id: A0A146WAM8
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105918551
gene id: 8078:LOC105918551
uniprot id: A0A3Q2PEH6
names: Subcellular Location Annotation
messages: extracellular space

8078:pigf
gene id: 8078:pigf
uniprot id: A0A3Q2SY40
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:tead1a
gene id: 8078:tead1a
uniprot id: A0A147A599
names: Subcellular Location Annotation
messages: Nucleus

8078:slc4a2b
gene id: 8078:slc4a2b
uniprot id: A0A3Q2PQZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane
messages: Plasma membrane anion exchange protein of wide distribution.

8078:eif4g3a
gene id: 8078:eif4g3a
uniprot id: A0A3Q2PEB5
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

8078:LOC105927176
gene id: 8078:LOC105927176
uniprot id: A0A3Q2QFU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8078:cldn15a
gene id: 8078:cldn15a
uniprot id: A0A3Q2PQ21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8078:slc25a34
gene id: 8078:slc25a34
uniprot id: A0A3Q2NWD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:paqr3a
gene id: 8078:paqr3a
uniprot id: A0A3Q2PEC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8078:KEG95 p10
gene id: 8078:KEG95_p10
uniprot id: B7U7V6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8078:LOC105934446
gene id: 8078:LOC105934446
uniprot id: A0A3Q2QAL7
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:pamr1
gene id: 8078:pamr1
uniprot id: A0A3Q2P8B2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8078:rps16
gene id: 8078:rps16
uniprot id: A0A3Q2TS26
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

8078:fam219aa
gene id: 8078:fam219aa
uniprot id: A0A146ZZQ7
names: Similarity
messages: Belongs to the FAM219 family.

8078:qkia
gene id: 8078:qkia
uniprot id: A0A147A804
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8078:kcnk12
gene id: 8078:kcnk12
uniprot id: A0A3Q2QCG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8078:hnrnpub
gene id: 8078:hnrnpub
uniprot id: A0A146ZPG4
names: Subcellular Location Annotation
messages: Nucleus

8078:tmem9
gene id: 8078:tmem9
uniprot id: A0A146P6Y4
names: Similarity
messages: Belongs to the TMEM9 family.

8078:LOC105928901
gene id: 8078:LOC105928901
uniprot id: A0A3Q2NMV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8078:LOC105934276
gene id: 8078:LOC105934276
uniprot id: A0A3Q2TFK1
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

8078:LOC105927346
gene id: 8078:LOC105927346
uniprot id: A0A3Q2PU76
names: Similarity
messages: Belongs to the CDR2 family.

8078:LOC105934153
gene id: 8078:LOC105934153
uniprot id: A0A3Q2NP56
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:slc25a10
gene id: 8078:slc25a10
uniprot id: A0A3Q2QIK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:cds2
gene id: 8078:cds2
uniprot id: A0A3Q2QCI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

8078:LOC105934893
gene id: 8078:LOC105934893
uniprot id: A0A146ZUT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:LOC105917269
gene id: 8078:LOC105917269
uniprot id: A0A3Q2Q6S2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8078:LOC105933169
gene id: 8078:LOC105933169
uniprot id: A0A3Q2PTI0
names: Similarity
messages: Belongs to the alkaline phosphatase family.

8078:ube2e1
gene id: 8078:ube2e1
uniprot id: A0A3Q2PVV6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:trabd2a
gene id: 8078:trabd2a
uniprot id: A0A147A1E3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

8078:LOC105936162
gene id: 8078:LOC105936162
uniprot id: A0A3Q2QHT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

8078:LOC105935934
gene id: 8078:LOC105935934
uniprot id: A0A3Q2QYH3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8078:rsl24d1
gene id: 8078:rsl24d1
uniprot id: A0A3Q2PBL6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

8078:galnt3
gene id: 8078:galnt3
uniprot id: A0A147AM81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8078:nat15
gene id: 8078:nat15
uniprot id: A0A146P6E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

8078:ddx3xa
gene id: 8078:ddx3xa
uniprot id: A0A3Q2QHW6
names: Similarity
messages: Belongs to the DEAD box helicase family.

8078:LOC105915630
gene id: 8078:LOC105915630
uniprot id: A0A3Q2Q3J5
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

8078:bbs5
gene id: 8078:bbs5
uniprot id: A0A3Q2Q383
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: centriolar satellite
messages: cilium membrane

8078:LOC105931401
gene id: 8078:LOC105931401
uniprot id: A0A3Q2PWM2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: caveola

8078:LOC105939657
gene id: 8078:LOC105939657
uniprot id: A0A3Q2P147
names: Subcellular Location Annotation
messages: extracellular space

8078:LOC105935101
gene id: 8078:LOC105935101
uniprot id: A0A3Q2PC73
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

8078:cmtm7
gene id: 8078:cmtm7
uniprot id: A0A3Q2PU03
names: Subcellular Location Annotation
messages: Membrane

8078:llgl1
gene id: 8078:llgl1
uniprot id: A0A3Q2NXB7
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

8078:fxyd7
gene id: 8078:fxyd7
uniprot id: A0A147ABF4
names: Similarity
messages: Belongs to the FXYD family.

8078:thrsp
gene id: 8078:thrsp
uniprot id: A0A3Q2QR18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

8078:dpys
gene id: 8078:dpys
uniprot id: A0A3Q2PA98
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

8078:hsd17b12a
gene id: 8078:hsd17b12a
uniprot id: A0A3Q2PV17
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:nkx2.3
gene id: 8078:nkx2.3
uniprot id: A0A3Q2NR81
names: Subcellular Location Annotation
messages: Nucleus

8078:mrpl49
gene id: 8078:mrpl49
uniprot id: A0A3Q2PDZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

8078:mtnr1c
gene id: 8078:mtnr1c
uniprot id: A0A3Q2P6Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

8078:necap1
gene id: 8078:necap1
uniprot id: A0A3Q2QTT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

8078:skp1
gene id: 8078:skp1
uniprot id: A0A3Q2QXP9
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.

8078:fam72a
gene id: 8078:fam72a
uniprot id: A0A146NMS8
names: Similarity
messages: Belongs to the FAM72 family.

8078:pus3
gene id: 8078:pus3
uniprot id: A0A146NPH3
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

8078:echdc2
gene id: 8078:echdc2
uniprot id: A0A3Q2SN85
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

8078:LOC105933136
gene id: 8078:LOC105933136
uniprot id: A0A3Q2QYE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

8078:uncx
gene id: 8078:uncx
uniprot id: A0A3Q2TD36
names: Subcellular Location Annotation
messages: Nucleus

8078:dgke
gene id: 8078:dgke
uniprot id: A0A146ZJ99
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8078:slc25a1b
gene id: 8078:slc25a1b
uniprot id: A0A3Q2PXC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:rorb
gene id: 8078:rorb
uniprot id: A0A146PMM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:rgs7bpa
gene id: 8078:rgs7bpa
uniprot id: A0A3Q2PS94
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

8078:stc2a
gene id: 8078:stc2a
uniprot id: A0A3Q2QE75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

8078:LOC105921160
gene id: 8078:LOC105921160
uniprot id: A0A3Q2NXT6
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:kcnj5
gene id: 8078:kcnj5
uniprot id: A0A147B2T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8078:wapla
gene id: 8078:wapla
uniprot id: A0A3Q2PX62
names: Similarity
messages: Belongs to the WAPL family.

8078:LOC105940381
gene id: 8078:LOC105940381
uniprot id: A0A147B1H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

8078:stxbp3
gene id: 8078:stxbp3
uniprot id: A0A3Q2TZY2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8078:LOC105923320
gene id: 8078:LOC105923320
uniprot id: A0A147AIH8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:sqlea
gene id: 8078:sqlea
uniprot id: A0A3Q2T4I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

8078:LOC105940217
gene id: 8078:LOC105940217
uniprot id: A0A146PXI4
names: Similarity
messages: Belongs to the dickkopf family.

8078:coq9
gene id: 8078:coq9
uniprot id: A0A3Q2QZT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

8078:me2
gene id: 8078:me2
uniprot id: A0A3Q2QT56
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

8078:itm2ca
gene id: 8078:itm2ca
uniprot id: A0A3Q2PFV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8078:LOC105936208
gene id: 8078:LOC105936208
uniprot id: A0A147B185
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

8078:atp6v1d
gene id: 8078:atp6v1d
uniprot id: A0A147A243
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: clathrin-coated vesicle membrane

8078:trim3b
gene id: 8078:trim3b
uniprot id: A0A147AP22
uniprot id: A0A3Q2PD60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

8078:LOC105938393
gene id: 8078:LOC105938393
uniprot id: A0A3Q2UGB2
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105939372
gene id: 8078:LOC105939372
uniprot id: A0A146MLU0
uniprot id: A0A3Q2PX31
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8078:LOC105933260
gene id: 8078:LOC105933260
uniprot id: A0A3Q2UID0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8078:brms1
gene id: 8078:brms1
uniprot id: A0A3Q2T4Q4
names: Subcellular Location Annotation
messages: Nucleus

8078:spats2
gene id: 8078:spats2
uniprot id: A0A146VNM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPATS2 family.
messages: Cytoplasm

8078:mul1a
gene id: 8078:mul1a
uniprot id: A0A3Q2PX55
names: Subcellular Location Annotation
messages: Membrane

8078:emx2
gene id: 8078:emx2
uniprot id: A0A3Q2QVY3
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105925922
gene id: 8078:LOC105925922
uniprot id: A0A146Z4J1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

8078:LOC105930489
gene id: 8078:LOC105930489
uniprot id: A0A3Q2PGM2
names: Subcellular Location Annotation
messages: Membrane

8078:dync2li1
gene id: 8078:dync2li1
uniprot id: A0A3Q2TN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

8078:marveld1
gene id: 8078:marveld1
uniprot id: A0A3Q2Q698
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105932227
gene id: 8078:LOC105932227
uniprot id: A0A3Q2NV00
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8078:cd74a
gene id: 8078:cd74a
uniprot id: A0A146NX42
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:pygl
gene id: 8078:pygl
uniprot id: A0A3Q2SSZ1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

8078:zgc:65851
gene id: 8078:zgc:65851
uniprot id: A0A3Q2QCG4
names: Similarity
messages: Belongs to the intermediate filament family.

8078:rnaset2
gene id: 8078:rnaset2
uniprot id: A0A3Q2TP96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

8078:LOC105919371
gene id: 8078:LOC105919371
uniprot id: A0A3Q2PE59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8078:utp25
gene id: 8078:utp25
uniprot id: A0A146PAF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

8078:pus10
gene id: 8078:pus10
uniprot id: A0A3Q2SQW1
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

8078:aqp12
gene id: 8078:aqp12
uniprot id: A0A3Q2NN53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:sntg2
gene id: 8078:sntg2
uniprot id: A0A3Q2SU71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

8078:rbpjb
gene id: 8078:rbpjb
uniprot id: A0A3Q2PNS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

8078:LOC105918003
gene id: 8078:LOC105918003
uniprot id: A0A3Q2PZ60
names: Similarity
messages: Belongs to the BTG family.

8078:bxdc2
gene id: 8078:bxdc2
uniprot id: A0A3Q2U1R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

8078:LOC105939347
gene id: 8078:LOC105939347
uniprot id: A0A146P6I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

8078:smad1
gene id: 8078:smad1
uniprot id: A0A3Q2P3U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8078:n6amt1
gene id: 8078:n6amt1
uniprot id: A0A3Q2PVI3
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

8078:dsc2l
gene id: 8078:dsc2l
uniprot id: A0A3Q2TEA6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: desmosome

8078:prdm8
gene id: 8078:prdm8
uniprot id: A0A3Q2STQ8
names: Subcellular Location Annotation
messages: Nucleus

8078:trap1
gene id: 8078:trap1
uniprot id: A0A3Q2PB48
names: Similarity
messages: Belongs to the heat shock protein 90 family.

8078:LOC105926790
gene id: 8078:LOC105926790
uniprot id: A0A3Q2PYE2
names: Similarity
messages: Belongs to the PHYHIP family.

8078:ildr2
gene id: 8078:ildr2
uniprot id: A0A3Q2PHQ6
uniprot id: A0A3Q2PIQ9
uniprot id: A0A3Q2TBB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8078:ywhaz
gene id: 8078:ywhaz
uniprot id: Q9DF39
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8078:get4
gene id: 8078:get4
uniprot id: A0A3Q2QTI7
names: Similarity
messages: Belongs to the GET4 family.

8078:celsr2
gene id: 8078:celsr2
uniprot id: A0A3Q2NXZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

8078:LOC105933032
gene id: 8078:LOC105933032
uniprot id: A0A3Q2R2L5
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8078:plxnd1
gene id: 8078:plxnd1
uniprot id: A0A146NXC4
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:ilk
gene id: 8078:ilk
uniprot id: A0A3Q2QVN5
names: Subcellular Location Annotation
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

8078:mrpl17
gene id: 8078:mrpl17
uniprot id: A0A3Q2SYD8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

8078:recql4
gene id: 8078:recql4
uniprot id: A0A3Q2QJN6
names: Subcellular Location Annotation
messages: Nucleus

8078:nlk1
gene id: 8078:nlk1
uniprot id: A0A3Q2R3A6
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8078:LOC105918170
gene id: 8078:LOC105918170
uniprot id: A0A147B5Q3
names: Similarity
messages: Belongs to the FAM53 family.

8078:LOC105931131
gene id: 8078:LOC105931131
uniprot id: A0A3Q2SWV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:foxh1
gene id: 8078:foxh1
uniprot id: A0A147B388
names: Subcellular Location Annotation
messages: Nucleus

8078:chmp5b
gene id: 8078:chmp5b
uniprot id: A0A3Q2QML7
names: Similarity
messages: Belongs to the SNF7 family.

8078:zgc:85777
gene id: 8078:zgc:85777
uniprot id: A0A3Q2PE61
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8078:pmepa1
gene id: 8078:pmepa1
uniprot id: A0A147AM68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

8078:LOC105926391
gene id: 8078:LOC105926391
uniprot id: A0A146P925
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:alg6
gene id: 8078:alg6
uniprot id: A0A3Q2Q522
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:pafah1b1b
gene id: 8078:pafah1b1b
uniprot id: A0A146NG06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Component of the cytosolic PAF-AH (I) heterotetrameric enzyme, which is composed of PAFAH1B1 (beta), PAFAH1B2 (alpha2) and PAFAH1B3 (alpha1) subunits. The catalytic activity of the enzyme resides in the alpha1 (PAFAH1B3) and alpha2 (PAFAH1B2) subunits, whereas the beta subunit (PAFAH1B1) has regulatory activity. Trimer formation is not essential for the catalytic activity (By similarity). Interacts with dynein, dynactin, nde1 and ndel1.
messages: Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
messages: centrosome
messages: cytoskeleton

8078:LOC105921089
gene id: 8078:LOC105921089
uniprot id: A0A3Q2NY90
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8078:LOC105927090
gene id: 8078:LOC105927090
uniprot id: A0A3Q2Q7H0
uniprot id: A0A3Q2Q7H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

8078:hpxb
gene id: 8078:hpxb
uniprot id: A0A3Q2PIT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemopexin family.
messages: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
messages: Secreted

8078:LOC105929863
gene id: 8078:LOC105929863
uniprot id: A0A146P376
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

8078:tasp1
gene id: 8078:tasp1
uniprot id: A0A3Q2R1C7
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8078:jak2b
gene id: 8078:jak2b
uniprot id: A0A3Q2NVM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

8078:dop1a
gene id: 8078:dop1a
uniprot id: A0A3Q2P8H4
names: Similarity
messages: Belongs to the dopey family.

8078:LOC105918783
gene id: 8078:LOC105918783
uniprot id: A0A3Q2QME6
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105934266
gene id: 8078:LOC105934266
uniprot id: A0A146ZUX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

8078:orc4
gene id: 8078:orc4
uniprot id: A0A3Q2U1V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

8078:ywhaba
gene id: 8078:ywhaba
uniprot id: A0A146Z0X1
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8078:polrmt
gene id: 8078:polrmt
uniprot id: A0A3Q2R093
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

8078:LOC105935986
gene id: 8078:LOC105935986
uniprot id: A0A3Q2PPX5
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

8078:tmed10
gene id: 8078:tmed10
uniprot id: A0A3Q2NNW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:mgat1a
gene id: 8078:mgat1a
uniprot id: A0A3Q2R0D0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

8078:gabpa
gene id: 8078:gabpa
uniprot id: A0A3Q2QUQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:sf3b5
gene id: 8078:sf3b5
uniprot id: A0A3Q2PWV9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

8078:LOC105917267
gene id: 8078:LOC105917267
uniprot id: A0A146YHG5
names: Similarity
messages: Belongs to the DNase I family.

8078:chrm5b
gene id: 8078:chrm5b
uniprot id: A0A3Q2QHL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8078:LOC105931812
gene id: 8078:LOC105931812
uniprot id: A0A3Q2QB35
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

8078:c2h16orf70
gene id: 8078:c2h16orf70
uniprot id: A0A146P5T8
names: Similarity
messages: Belongs to the PHAF1 family.

8078:LOC105921936
gene id: 8078:LOC105921936
uniprot id: A0A3Q2T491
names: Similarity
messages: Belongs to the PPP phosphatase family.

8078:LOC105919524
gene id: 8078:LOC105919524
uniprot id: A0A3Q2QCY6
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

8078:tmem8b
gene id: 8078:tmem8b
uniprot id: A0A147A6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

8078:pgm3
gene id: 8078:pgm3
uniprot id: A0A3Q2P6Z2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

8078:slc25a42
gene id: 8078:slc25a42
uniprot id: A0A3Q2SRA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:ccdc43
gene id: 8078:ccdc43
uniprot id: A0A3Q2QKZ8
names: Similarity
messages: Belongs to the CCDC43 family.

8078:stoml2
gene id: 8078:stoml2
uniprot id: A0A3Q2PJ99
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8078:rpl27a
gene id: 8078:rpl27a
uniprot id: A0A3Q2PWJ4
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

8078:ndufa10
gene id: 8078:ndufa10
uniprot id: A0A3Q2NZL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.
messages: Mitochondrion matrix

8078:ppp2r3c
gene id: 8078:ppp2r3c
uniprot id: A0A147AC67
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8078:mindy3
gene id: 8078:mindy3
uniprot id: A0A3Q2QUI8
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

8078:LOC105932944
gene id: 8078:LOC105932944
uniprot id: A0A146ZXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane

8078:naif1
gene id: 8078:naif1
uniprot id: A0A3Q2NW08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

8078:LOC105932256
gene id: 8078:LOC105932256
uniprot id: A0A3Q2NX40
uniprot id: A0A3Q2QAB9
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

8078:slc52a3
gene id: 8078:slc52a3
uniprot id: A0A146P500
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

8078:psmc4
gene id: 8078:psmc4
uniprot id: A0A146P6E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
messages: Cytoplasm

8078:ribc2
gene id: 8078:ribc2
uniprot id: A0A3Q2U4D0
names: Similarity
messages: Belongs to the RIB43A family.

8078:traf2b
gene id: 8078:traf2b
uniprot id: A0A146RFG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8078:LOC105930929
gene id: 8078:LOC105930929
uniprot id: A0A3Q2T5K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

8078:LOC105928311
gene id: 8078:LOC105928311
uniprot id: A0A3Q2P4P6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with RET in the pituitary gland; this interaction prevents the formation of the AIP-survivin complex.
messages: May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.

8078:foxm1
gene id: 8078:foxm1
uniprot id: A0A3Q2Q0A4
names: Subcellular Location Annotation
messages: Nucleus

8078:sgf29
gene id: 8078:sgf29
uniprot id: A0A3Q2Q3B5
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105917881
gene id: 8078:LOC105917881
uniprot id: A0A3Q2Q9M8
uniprot id: A0A3Q2QAI0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

8078:ccnh
gene id: 8078:ccnh
uniprot id: A0A3Q2QF23
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

8078:slc44a4
gene id: 8078:slc44a4
uniprot id: A0A3Q2QFF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8078:si:ch211-30b16.2
gene id: 8078:si:ch211-30b16.2
uniprot id: A0A3Q2UM46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:coro2a
gene id: 8078:coro2a
uniprot id: A0A3Q2QWZ4
uniprot id: A0A3Q2QYL2
names: Similarity
messages: Belongs to the WD repeat coronin family.

8078:trmt10c
gene id: 8078:trmt10c
uniprot id: A0A3Q2QRM8
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

8078:si:ch211-286o17.1
gene id: 8078:si:ch211-286o17.1
uniprot id: A0A3Q2UJA6
names: Subcellular Location Annotation
messages: Membrane

8078:ptgdsa
gene id: 8078:ptgdsa
uniprot id: A0A3Q2QKT4
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8078:zbed4
gene id: 8078:zbed4
uniprot id: A0A3Q2QDQ6
names: Subcellular Location Annotation
messages: Nucleus

8078:hdac4
gene id: 8078:hdac4
uniprot id: A0A146VKQ0
uniprot id: A0A146ZTC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

8078:yy1a
gene id: 8078:yy1a
uniprot id: A0A3Q2QFD1
names: Similarity
messages: Belongs to the YY transcription factor family.

8078:LOC105932434
gene id: 8078:LOC105932434
uniprot id: A0A146ZZQ1
names: Subcellular Location Annotation
messages: extracellular space

8078:LOC105925834
gene id: 8078:LOC105925834
uniprot id: A0A3Q2QT29
names: Similarity
messages: Belongs to the peptidase S1B family.

8078:ttll1
gene id: 8078:ttll1
uniprot id: A0A3Q2QBS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin polyglutamylase family.
messages: cilium basal body

8078:LOC105918069
gene id: 8078:LOC105918069
uniprot id: A0A147AUW6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:fdxr
gene id: 8078:fdxr
uniprot id: A0A3Q2PQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion
messages: Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

8078:zgc:110410
gene id: 8078:zgc:110410
uniprot id: A0A3Q2SU56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8078:LOC105938047
gene id: 8078:LOC105938047
uniprot id: A0A3Q2SVS1
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105930161
gene id: 8078:LOC105930161
uniprot id: A0A3Q2Q120
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

8078:vti1a
gene id: 8078:vti1a
uniprot id: A0A146RUY0
uniprot id: A0A3Q2QU07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

8078:zdhhc20a
gene id: 8078:zdhhc20a
uniprot id: A0A3Q2QTD9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8078:cd151
gene id: 8078:cd151
uniprot id: A0A3Q2Q0G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:LOC105936190
gene id: 8078:LOC105936190
uniprot id: A0A3Q2P5Z2
names: Subcellular Location Annotation
messages: Nucleus

8078:rbp7a
gene id: 8078:rbp7a
uniprot id: A0A3Q2P549
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8078:dynll2a
gene id: 8078:dynll2a
uniprot id: A0A147B751
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8078:pex13
gene id: 8078:pex13
uniprot id: A0A3Q2QWX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

8078:si:ch211-130m23.3
gene id: 8078:si:ch211-130m23.3
uniprot id: A0A146XAX9
names: Subcellular Location Annotation
messages: Nucleus

8078:ndufb4
gene id: 8078:ndufb4
uniprot id: A0A3Q2Q8U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8078:LOC105932549
gene id: 8078:LOC105932549
uniprot id: A0A3Q2UMF1
names: Similarity
messages: Belongs to the SLITRK family.

8078:hsd20b2
gene id: 8078:hsd20b2
uniprot id: A0A3Q2TZI7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:sdr42e1
gene id: 8078:sdr42e1
uniprot id: A0A3Q2R0C2
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8078:btg3
gene id: 8078:btg3
uniprot id: A0A146P4H4
names: Similarity
messages: Belongs to the BTG family.

8078:LOC105939744
gene id: 8078:LOC105939744
uniprot id: A0A146QK76
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

8078:syvn1
gene id: 8078:syvn1
uniprot id: A0A146WL55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRD1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:dpep1
gene id: 8078:dpep1
uniprot id: A0A3Q2ULP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

8078:si:dkey-261h17.1
gene id: 8078:si:dkey-261h17.1
uniprot id: A0A3Q2P1V7
names: Subcellular Location Annotation
messages: Membrane

8078:ube4b
gene id: 8078:ube4b
uniprot id: A0A146P4M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

8078:slc47a3
gene id: 8078:slc47a3
uniprot id: A0A3Q2Q9W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

8078:LOC105932789
gene id: 8078:LOC105932789
uniprot id: A0A3Q2PBT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

8078:leo1
gene id: 8078:leo1
uniprot id: A0A3Q2QFT8
names: Similarity
messages: Belongs to the LEO1 family.

8078:LOC105931415
gene id: 8078:LOC105931415
uniprot id: A0A147A0Q6
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8078:mtmr7a
gene id: 8078:mtmr7a
uniprot id: A0A147A505
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8078:otulina
gene id: 8078:otulina
uniprot id: A0A3Q2T6M3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8078:LOC105921046
gene id: 8078:LOC105921046
uniprot id: A0A146NYH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

8078:LOC105930979
gene id: 8078:LOC105930979
uniprot id: A0A3Q2PGL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8078:fgf18a
gene id: 8078:fgf18a
uniprot id: A0A3Q2NQL7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8078:actr5
gene id: 8078:actr5
uniprot id: A0A146ZQP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family. ARP5 subfamily.
messages: Nucleus

8078:desi1a
gene id: 8078:desi1a
uniprot id: A0A3Q2NXP8
names: Similarity
messages: Belongs to the DeSI family.

8078:lsm12b
gene id: 8078:lsm12b
uniprot id: A0A3Q2TNF0
names: Similarity
messages: Belongs to the LSM12 family.

8078:ube2d4
gene id: 8078:ube2d4
uniprot id: A0A3Q2TPG5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:LOC105916461
gene id: 8078:LOC105916461
uniprot id: A0A3Q2QLI4
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105937322
gene id: 8078:LOC105937322
uniprot id: A0A3Q2NPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

8078:epoa
gene id: 8078:epoa
uniprot id: A0A3Q2PED5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
messages: Secreted

8078:anapc15
gene id: 8078:anapc15
uniprot id: A0A3Q2NSV0
names: Similarity
messages: Belongs to the APC15 family.

8078:irak1bp1
gene id: 8078:irak1bp1
uniprot id: A0A3Q2QZU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

8078:LOC105928332
gene id: 8078:LOC105928332
uniprot id: A0A3Q2QHZ7
names: Similarity
messages: Belongs to the HPF1 family.

8078:LOC105917279
gene id: 8078:LOC105917279
uniprot id: A0A3Q2Q5N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zyxin/ajuba family.
messages: Cytoplasm
messages: Nucleus

8078:kmt5c
gene id: 8078:kmt5c
uniprot id: A0A3Q2QC52
names: Subcellular Location Annotation
messages: Nucleus

8078:gna11b
gene id: 8078:gna11b
uniprot id: A0A3Q2P8M7
uniprot id: A0A3Q2P8N1
uniprot id: A0A3Q2QHL2
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8078:LOC105934564
gene id: 8078:LOC105934564
uniprot id: A0A3Q2NSA3
names: Similarity
messages: Belongs to the complex I LYR family.

8078:im:7138535
gene id: 8078:im:7138535
uniprot id: A0A3Q2SVV1
names: Similarity
messages: Belongs to the FAM98 family.

8078:LOC105937864
gene id: 8078:LOC105937864
uniprot id: A0A3Q2QQG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

8078:hdhd2
gene id: 8078:hdhd2
uniprot id: A0A3Q2NYJ3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

8078:LOC105933190
gene id: 8078:LOC105933190
uniprot id: A0A3Q2TFH7
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105922040
gene id: 8078:LOC105922040
uniprot id: A0A3Q2Q4H1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8078:LOC105938398
gene id: 8078:LOC105938398
uniprot id: A0A3Q2PHZ3
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8078:LOC105926860
gene id: 8078:LOC105926860
uniprot id: A0A3Q2TL04
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8078:map3k12
gene id: 8078:map3k12
uniprot id: A0A147A6A2
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: May be an activator of the JNK/SAPK pathway.

8078:foxe3
gene id: 8078:foxe3
uniprot id: A0A147A8G5
names: Subcellular Location Annotation
messages: Nucleus

8078:ivd
gene id: 8078:ivd
uniprot id: A0A3Q2QET0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8078:exoc1
gene id: 8078:exoc1
uniprot id: A0A3Q2NNL1
names: Similarity
messages: Belongs to the SEC3 family.

8078:pde7a
gene id: 8078:pde7a
uniprot id: A0A146YX53
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8078:aspa
gene id: 8078:aspa
uniprot id: A0A3Q2P068
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

8078:vgll4a
gene id: 8078:vgll4a
uniprot id: A0A3Q2NSU9
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

8078:dlx3b
gene id: 8078:dlx3b
uniprot id: A0A147B0M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8078:LOC105926719
gene id: 8078:LOC105926719
uniprot id: A0A3Q2NRI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

8078:LOC105915281
gene id: 8078:LOC105915281
uniprot id: A0A147B1C3
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105916103
gene id: 8078:LOC105916103
uniprot id: A0A146YQ69
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
messages: Nucleus matrix
messages: The LD (leucine and aspartate-rich) motif 3 mediates interaction with GIT1 and functions as a nuclear export signal.
messages: cytoskeleton
messages: focal adhesion

8078:pdcb
gene id: 8078:pdcb
uniprot id: A0A147AWP2
names: Similarity
messages: Belongs to the phosducin family.

8078:tpm4a
gene id: 8078:tpm4a
uniprot id: A0A146P4T3
uniprot id: A0A3Q2Q9D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8078:LOC105926383
gene id: 8078:LOC105926383
uniprot id: A0A146X4E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

8078:LOC105927083
gene id: 8078:LOC105927083
uniprot id: A0A3Q2NXP1
names: Subcellular Location Annotation
messages: Membrane
messages: basement membrane

8078:LOC105939525
gene id: 8078:LOC105939525
uniprot id: A0A3Q2T707
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8078:aldob
gene id: 8078:aldob
uniprot id: A0A3Q2U5N4
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

8078:LOC105922761
gene id: 8078:LOC105922761
uniprot id: A0A3Q2P3X0
names: Similarity
messages: Belongs to the cornifelin family.

8078:trpv1
gene id: 8078:trpv1
uniprot id: A0A3Q2T7K8
names: Subcellular Location Annotation
messages: Membrane

8078:gpm6bb
gene id: 8078:gpm6bb
uniprot id: A0A3Q2R282
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8078:gtf2b
gene id: 8078:gtf2b
uniprot id: A0A3Q2PR97
names: Similarity
messages: Belongs to the TFIIB family.
messages: Belongs to the cyclin family. Cyclin AB subfamily.

8078:LOC105926332
gene id: 8078:LOC105926332
uniprot id: A0A147ABN7
names: Similarity
messages: Belongs to the stathmin family.

8078:LOC105916143
gene id: 8078:LOC105916143
uniprot id: A0A146YR48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8078:LOC105921507
gene id: 8078:LOC105921507
uniprot id: A0A3Q2UQ84
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

8078:cnrip1b
gene id: 8078:cnrip1b
uniprot id: A0A146ZWT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

8078:lancl2
gene id: 8078:lancl2
uniprot id: A0A146XUA1
names: Similarity
messages: Belongs to the LanC-like protein family.

8078:atf7b
gene id: 8078:atf7b
uniprot id: A0A146VD53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

8078:eda
gene id: 8078:eda
uniprot id: A0A3Q2T2K8
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8078:efna5b
gene id: 8078:efna5b
uniprot id: A0A3Q2PTT1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:znf503
gene id: 8078:znf503
uniprot id: A0A3Q2QQV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

8078:si:dkeyp-23e4.3
gene id: 8078:si:dkeyp-23e4.3
uniprot id: A0A3Q2PN87
uniprot id: A0A3Q2PPF3
names: Subcellular Location Annotation
messages: Cytoplasm

8078:gatb
gene id: 8078:gatb
uniprot id: A0A146P799
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

8078:LOC105929809
gene id: 8078:LOC105929809
uniprot id: A0A3Q2QUU9
names: Similarity
messages: Belongs to the TAFA family.

8078:LOC105927271
gene id: 8078:LOC105927271
uniprot id: A0A147A9I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:LOC105931335
gene id: 8078:LOC105931335
uniprot id: A0A3Q2PVE3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

8078:klhl21
gene id: 8078:klhl21
uniprot id: A0A3Q2NU56
names: Subcellular Location Annotation
messages: spindle

8078:rnasekb
gene id: 8078:rnasekb
uniprot id: A0A3Q2PBF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane

8078:ano6
gene id: 8078:ano6
uniprot id: A0A3Q2QVZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

8078:cpz
gene id: 8078:cpz
uniprot id: A0A3Q2UGM9
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:st3gal5
gene id: 8078:st3gal5
uniprot id: A0A147ATU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8078:sv2ba
gene id: 8078:sv2ba
uniprot id: A0A3Q2TVG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8078:cxcl8a
gene id: 8078:cxcl8a
uniprot id: A0A3Q2P873
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

8078:mtmr4
gene id: 8078:mtmr4
uniprot id: A0A3Q2QIJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

8078:epha2b
gene id: 8078:epha2b
uniprot id: A0A3Q2QNF3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:rad52
gene id: 8078:rad52
uniprot id: A0A3Q2QZE6
names: Similarity
messages: Belongs to the RAD52 family.

8078:cav3
gene id: 8078:cav3
uniprot id: A0A3Q2QBR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola
messages: sarcolemma

8078:LOC105917532
gene id: 8078:LOC105917532
uniprot id: A0A3Q2QTP7
names: Subcellular Location Annotation
names: Subunit
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

8078:unk
gene id: 8078:unk
uniprot id: A0A3Q2PQN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

8078:ddx47
gene id: 8078:ddx47
uniprot id: A0A3Q2UBY2
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

8078:LOC105936689
gene id: 8078:LOC105936689
uniprot id: A0A3Q2P892
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8078:LOC105916429
gene id: 8078:LOC105916429
uniprot id: A0A3Q2UFU6
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

8078:ap3d1
gene id: 8078:ap3d1
uniprot id: A0A146VDS6
uniprot id: A0A3Q2NV63
uniprot id: A0A3Q2NVT2
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8078:epn3a
gene id: 8078:epn3a
uniprot id: A0A3Q2PJB4
names: Similarity
messages: Belongs to the epsin family.

8078:LOC105926221
gene id: 8078:LOC105926221
uniprot id: A0A3Q2QA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

8078:tnfrsf1a
gene id: 8078:tnfrsf1a
uniprot id: A0A3Q2PH96
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105938462
gene id: 8078:LOC105938462
uniprot id: A0A3Q2T823
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

8078:LOC105921773
gene id: 8078:LOC105921773
uniprot id: A0A146Z782
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

8078:clptm1
gene id: 8078:clptm1
uniprot id: A0A3Q2SY06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

8078:pkn1b
gene id: 8078:pkn1b
uniprot id: A0A3Q2P7L9
uniprot id: A0A3Q2P7R3
uniprot id: A0A3Q2QJC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

8078:glulb
gene id: 8078:glulb
uniprot id: A0A146P4K3
names: Similarity
messages: Belongs to the glutamine synthetase family.

8078:slx4
gene id: 8078:slx4
uniprot id: A0A3Q2PEE9
names: Similarity
messages: Belongs to the SLX4 family.

8078:mif
gene id: 8078:mif
uniprot id: Q0ZBS1
names: Similarity
messages: Belongs to the MIF family.

8078:xylt1
gene id: 8078:xylt1
uniprot id: A0A3Q2PNY0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

8078:ciao1
gene id: 8078:ciao1
uniprot id: A0A3Q2NV57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.

8078:LOC105928662
gene id: 8078:LOC105928662
uniprot id: A0A3Q2NUG8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

8078:optn
gene id: 8078:optn
uniprot id: A0A3Q2ULM9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Endosome
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

8078:aco1
gene id: 8078:aco1
uniprot id: A0A3Q2NZ03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Conversely, when cellular iron levels are high, binds a 4Fe-4S cluster which precludes RNA binding activity and promotes the aconitase activity, the isomerization of citrate to isocitrate via cis-aconitate.
messages: cytosol

8078:wasf2
gene id: 8078:wasf2
uniprot id: A0A147B3I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8078:mpv17
gene id: 8078:mpv17
uniprot id: A0A3Q2PB80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

8078:plxna4
gene id: 8078:plxna4
uniprot id: A0A3Q2R115
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105939791
gene id: 8078:LOC105939791
uniprot id: A0A3Q2NS07
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:isy1
gene id: 8078:isy1
uniprot id: A0A3Q2QDX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

8078:crx
gene id: 8078:crx
uniprot id: A0A3Q2NWA6
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105915748
gene id: 8078:LOC105915748
uniprot id: A0A3Q2QWJ3
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105931958
gene id: 8078:LOC105931958
uniprot id: A0A3Q2PRH9
uniprot id: A0A3Q2TH84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

8078:chst12a
gene id: 8078:chst12a
uniprot id: A0A147AZT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:LOC105929399
gene id: 8078:LOC105929399
uniprot id: A0A3Q2TX75
names: Similarity
messages: Belongs to the calponin family.

8078:LOC105916801
gene id: 8078:LOC105916801
uniprot id: A0A3Q2PYW4
names: Subcellular Location Annotation
messages: Membrane

8078:dpf3
gene id: 8078:dpf3
uniprot id: A0A146ZN74
uniprot id: A0A3Q2PZB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the requiem/DPF family.
messages: Nucleus

8078:wfikkn1
gene id: 8078:wfikkn1
uniprot id: A0A3Q2R270
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Membrane

8078:cdc42ep4b
gene id: 8078:cdc42ep4b
uniprot id: A0A3Q2PZC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8078:vps52
gene id: 8078:vps52
uniprot id: A0A146XWE8
names: Similarity
messages: Belongs to the VPS52 family.

8078:timm13
gene id: 8078:timm13
uniprot id: A0A3Q2QE13
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8078:dnaja
gene id: 8078:dnaja
uniprot id: A0A3Q2SPY0
names: Subcellular Location Annotation
messages: Membrane

8078:cpda
gene id: 8078:cpda
uniprot id: A0A3Q2QZH7
names: Similarity
messages: Belongs to the peptidase M14 family.

8078:KEG95 p11
gene id: 8078:KEG95_p11
uniprot id: B7U7V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8078:arl8bb
gene id: 8078:arl8bb
uniprot id: A0A3Q2PX03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8078:atp1a2a
gene id: 8078:atp1a2a
uniprot id: Q8AY57
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:zgc:158291
gene id: 8078:zgc:158291
uniprot id: A0A3Q2NZI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8078:LOC105926571
gene id: 8078:LOC105926571
uniprot id: A0A3Q2Q8X0
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:pdk2a
gene id: 8078:pdk2a
uniprot id: C6ZDP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8078:cltca
gene id: 8078:cltca
uniprot id: A0A3Q2UIA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

8078:trabd2b
gene id: 8078:trabd2b
uniprot id: A0A3Q2Q3P5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

8078:pdk3a
gene id: 8078:pdk3a
uniprot id: A0A3Q2QBK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8078:eef1db
gene id: 8078:eef1db
uniprot id: A0A3Q2P382
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

8078:LOC105932294
gene id: 8078:LOC105932294
uniprot id: A0A3Q2QD78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

8078:LOC105916184
gene id: 8078:LOC105916184
uniprot id: A0A146P9L1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8078:amacr
gene id: 8078:amacr
uniprot id: A0A3Q2Q8M3
names: Similarity
messages: Belongs to the CoA-transferase III family.

8078:nemp1
gene id: 8078:nemp1
uniprot id: A0A3Q2NZK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

8078:snw1
gene id: 8078:snw1
uniprot id: A0A146NNG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

8078:klhl15
gene id: 8078:klhl15
uniprot id: A0A3Q2QCV8
names: Subcellular Location Annotation
messages: Nucleus

8078:spaw
gene id: 8078:spaw
uniprot id: A0A3Q2UJN3
names: Similarity
messages: Belongs to the TGF-beta family.

8078:cog8
gene id: 8078:cog8
uniprot id: A0A3Q2QFU1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG8 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane

8078:spic
gene id: 8078:spic
uniprot id: A0A146ZVP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:rag2
gene id: 8078:rag2
uniprot id: A0A147AUJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

8078:napbb
gene id: 8078:napbb
uniprot id: A0A3Q2PXP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

8078:LOC105930577
gene id: 8078:LOC105930577
uniprot id: A0A3Q2P7H6
names: Similarity
messages: Belongs to the TENT family.

8078:cd4-2.2
gene id: 8078:cd4-2.2
uniprot id: A0A3Q2PD16
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105925570
gene id: 8078:LOC105925570
uniprot id: A0A146X7M9
names: Similarity
messages: Belongs to the RASGRP family.

8078:atf1
gene id: 8078:atf1
uniprot id: A0A146ZQC9
names: Subcellular Location Annotation
messages: Nucleus

8078:btg1
gene id: 8078:btg1
uniprot id: A0A3Q2QB49
names: Function
names: Similarity
messages: Anti-proliferative protein.
messages: Belongs to the BTG family.

8078:dnajc16l
gene id: 8078:dnajc16l
uniprot id: A0A3Q2P000
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105936023
gene id: 8078:LOC105936023
uniprot id: A0A147B5H6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:cdk20
gene id: 8078:cdk20
uniprot id: A0A3Q2PG68
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:st3gal7
gene id: 8078:st3gal7
uniprot id: A0A146ZL39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8078:zdhhc12b
gene id: 8078:zdhhc12b
uniprot id: A0A3Q2QCW3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8078:LOC105921484
gene id: 8078:LOC105921484
uniprot id: A0A3Q2TTT7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8078:LOC105937305
gene id: 8078:LOC105937305
uniprot id: A0A3Q2NPU3
names: Similarity
messages: Belongs to the globin family.

8078:LOC105928053
gene id: 8078:LOC105928053
uniprot id: A0A3Q2QV58
names: Similarity
messages: Belongs to the TCP11 family.

8078:LOC105925726
gene id: 8078:LOC105925726
uniprot id: A0A3Q2QEI3
names: Similarity
messages: Belongs to the peptidase M10A family.

8078:lim2.2
gene id: 8078:lim2.2
uniprot id: A0A146W2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

8078:sh3bgrl2
gene id: 8078:sh3bgrl2
uniprot id: A0A3Q2PVH7
names: Similarity
messages: Belongs to the SH3BGR family.

8078:snrnp27
gene id: 8078:snrnp27
uniprot id: A0A3Q2QBM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

8078:etsrp
gene id: 8078:etsrp
uniprot id: A0A3Q2PCS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:tp53inp1
gene id: 8078:tp53inp1
uniprot id: A0A3Q2PI97
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

8078:waslb
gene id: 8078:waslb
uniprot id: A0A3Q2TJX5
names: Subcellular Location Annotation
messages: Nucleus

8078:foxj2
gene id: 8078:foxj2
uniprot id: A0A3Q2PLW6
names: Subcellular Location Annotation
messages: Nucleus

8078:hdac1
gene id: 8078:hdac1
uniprot id: A0A3Q2PPP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also functions as deacetylase for non-histone proteins.
messages: Nucleus

8078:ep300b
gene id: 8078:ep300b
uniprot id: A0A147AV07
names: Subcellular Location Annotation
messages: Cytoplasm

8078:LOC105934272
gene id: 8078:LOC105934272
uniprot id: A0A3Q2TFR3
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

8078:rnaseh2b
gene id: 8078:rnaseh2b
uniprot id: A0A146P2E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

8078:ints11
gene id: 8078:ints11
uniprot id: A0A3Q2P410
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Nucleus

8078:sox14
gene id: 8078:sox14
uniprot id: A0A3Q2SUW3
names: Subcellular Location Annotation
messages: Nucleus

8078:cbwd
gene id: 8078:cbwd
uniprot id: A0A3Q2PRA0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

8078:sh2b1
gene id: 8078:sh2b1
uniprot id: A0A3Q2R2E0
names: Similarity
messages: Belongs to the SH2B adapter family.

8078:rspo3
gene id: 8078:rspo3
uniprot id: A0A146RV12
names: Similarity
messages: Belongs to the R-spondin family.

8078:cnot7
gene id: 8078:cnot7
uniprot id: A0A3Q2QRY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

8078:scdb
gene id: 8078:scdb
uniprot id: A0A3Q2Q0S4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

8078:prkacba
gene id: 8078:prkacba
uniprot id: A0A3Q2NV38
uniprot id: A0A3Q2NV46
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

8078:LOC105939846
gene id: 8078:LOC105939846
uniprot id: A0A3Q2TUY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8078:psmb1
gene id: 8078:psmb1
uniprot id: A0A146MJP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

8078:nt5dc1
gene id: 8078:nt5dc1
uniprot id: A0A147ASM8
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

8078:foxd2
gene id: 8078:foxd2
uniprot id: A0A147A7M4
names: Subcellular Location Annotation
messages: Nucleus

8078:ckap2l
gene id: 8078:ckap2l
uniprot id: A0A3Q2Q3K0
names: Similarity
messages: Belongs to the CKAP2 family.

8078:chmp2a
gene id: 8078:chmp2a
uniprot id: A0A3Q2NYK5
names: Similarity
messages: Belongs to the SNF7 family.

8078:tmem254
gene id: 8078:tmem254
uniprot id: A0A3Q2TQB5
names: Subcellular Location Annotation
messages: Membrane

8078:fahd1
gene id: 8078:fahd1
uniprot id: A0A3Q2R481
names: Similarity
messages: Belongs to the FAH family.

8078:fgf2
gene id: 8078:fgf2
uniprot id: A0A146ZN04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Nucleus
messages: Secreted

8078:arsk
gene id: 8078:arsk
uniprot id: A0A3Q2PTF4
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8078:eef1g
gene id: 8078:eef1g
uniprot id: A0A3Q2Q8D6
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

8078:LOC105916463
gene id: 8078:LOC105916463
uniprot id: A0A3Q2PFG9
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105921276
gene id: 8078:LOC105921276
uniprot id: A0A3Q2P5L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

8078:proza
gene id: 8078:proza
uniprot id: A0A3Q2QPG9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:meltf
gene id: 8078:meltf
uniprot id: A0A3Q2Q5R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted
messages: Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.

8078:mettl16
gene id: 8078:mettl16
uniprot id: A0A3Q2PZF2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

8078:znf706
gene id: 8078:znf706
uniprot id: A0A3Q2P5J4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8078:hoxb2a
gene id: 8078:hoxb2a
uniprot id: A0A3Q2PIG7
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105938740
gene id: 8078:LOC105938740
uniprot id: A0A3Q2R2K3
names: Subcellular Location Annotation
messages: Cytoplasm

8078:napba
gene id: 8078:napba
uniprot id: A0A3Q2PFI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

8078:ezrb
gene id: 8078:ezrb
uniprot id: A0A146WBW4
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8078:mpg
gene id: 8078:mpg
uniprot id: A0A3Q2NRV4
names: Function
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

8078:ankle2
gene id: 8078:ankle2
uniprot id: A0A3Q2QD34
names: Similarity
messages: Belongs to the ANKLE2 family.

8078:si:ch211-181l5.2
gene id: 8078:si:ch211-181l5.2
uniprot id: A0A3Q2QNW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8078:necap2
gene id: 8078:necap2
uniprot id: A0A3Q2NX48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

8078:LOC105927737
gene id: 8078:LOC105927737
uniprot id: A0A3Q2NVF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8078:armc1l
gene id: 8078:armc1l
uniprot id: A0A3Q2P526
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8078:flr
gene id: 8078:flr
uniprot id: A0A3Q2UKE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

8078:smpd1
gene id: 8078:smpd1
uniprot id: A0A3Q2PSV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

8078:zgc:110319
gene id: 8078:zgc:110319
uniprot id: A0A3Q2TYF3
names: Similarity
messages: Belongs to the NifU family.

8078:galns
gene id: 8078:galns
uniprot id: A0A3Q2QVZ9
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfatase family.
messages: Homodimer.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8078:cratb
gene id: 8078:cratb
uniprot id: A0A3Q2QG74
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8078:lrrc4.2
gene id: 8078:lrrc4.2
uniprot id: A0A147B0R3
names: Subcellular Location Annotation
messages: Membrane

8078:slc25a14
gene id: 8078:slc25a14
uniprot id: A0A3Q2NZT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:rhbdd3
gene id: 8078:rhbdd3
uniprot id: A0A3Q2PMW4
names: Subcellular Location Annotation
messages: Membrane

8078:pdia2
gene id: 8078:pdia2
uniprot id: A0A3Q2SQP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8078:chrnb2
gene id: 8078:chrnb2
uniprot id: A0A3Q2PXT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8078:dmac2l
gene id: 8078:dmac2l
uniprot id: A0A146W307
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP synthase subunit s family.
messages: Homotetramer. Associates with ATP synthase.
messages: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
messages: Membrane
messages: Mitochondrion inner membrane

8078:rpl21
gene id: 8078:rpl21
uniprot id: A0A3Q2QTL7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

8078:pprc1
gene id: 8078:pprc1
uniprot id: A0A3Q2NUS1
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105934088
gene id: 8078:LOC105934088
uniprot id: A0A146ZVL0
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

8078:ccdc85cb
gene id: 8078:ccdc85cb
uniprot id: A0A3Q2NYB7
uniprot id: A0A3Q2SVY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

8078:LOC105924362
gene id: 8078:LOC105924362
uniprot id: A0A3Q2SRD3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

8078:atg5
gene id: 8078:atg5
uniprot id: A0A3Q2U857
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

8078:rpf1
gene id: 8078:rpf1
uniprot id: A0A3Q2U1A0
names: Subcellular Location Annotation
messages: nucleolus

8078:LOC105939729
gene id: 8078:LOC105939729
uniprot id: A0A3Q2U226
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8078:grm1a
gene id: 8078:grm1a
uniprot id: A0A3Q2Q5U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8078:tgm2l
gene id: 8078:tgm2l
uniprot id: A0A3Q2STS9
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8078:LOC105916363
gene id: 8078:LOC105916363
uniprot id: A0A147AY15
names: Subcellular Location Annotation
messages: Nucleus

8078:snx3
gene id: 8078:snx3
uniprot id: A0A3Q2NMN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome
messages: Endosome
messages: phagosome

8078:ogfrl1
gene id: 8078:ogfrl1
uniprot id: A0A3Q2QWE2
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

8078:LOC105927645
gene id: 8078:LOC105927645
uniprot id: A0A3Q2QCV6
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8078:fgfbp2a
gene id: 8078:fgfbp2a
uniprot id: A0A146ZZN6
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

8078:acsl5
gene id: 8078:acsl5
uniprot id: A0A146V8A4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8078:itga1
gene id: 8078:itga1
uniprot id: A0A146V6U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8078:LOC105919514
gene id: 8078:LOC105919514
uniprot id: A0A3Q2P2Z1
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:adra2db
gene id: 8078:adra2db
uniprot id: A0A147B5S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:prim1
gene id: 8078:prim1
uniprot id: A0A3Q2PQJ5
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

8078:nubp1
gene id: 8078:nubp1
uniprot id: A0A3Q2Q9Z3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Cell projection
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

8078:wnt2ba
gene id: 8078:wnt2ba
uniprot id: A0A146ZRG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8078:dusp10
gene id: 8078:dusp10
uniprot id: A0A147A235
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8078:rcan3
gene id: 8078:rcan3
uniprot id: A0A3Q2P0P6
uniprot id: A0A3Q2QC21
names: Similarity
messages: Belongs to the RCAN family.

8078:LOC105926017
gene id: 8078:LOC105926017
uniprot id: A0A146PHH7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8078:aimp2
gene id: 8078:aimp2
uniprot id: A0A3Q2NSA6
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

8078:mrpl4
gene id: 8078:mrpl4
uniprot id: A0A3Q2SS70
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

8078:LOC105917509
gene id: 8078:LOC105917509
uniprot id: A0A3Q2TGP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

8078:stmn2b
gene id: 8078:stmn2b
uniprot id: A0A147A2D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stathmin family.
messages: Cytoplasm
messages: Membrane
messages: lamellipodium

8078:xylb
gene id: 8078:xylb
uniprot id: A0A146XXZ2
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

8078:glud1b
gene id: 8078:glud1b
uniprot id: A0A146P519
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

8078:atp6ap1a
gene id: 8078:atp6ap1a
uniprot id: A0A3Q2PQA0
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

8078:LOC105938994
gene id: 8078:LOC105938994
uniprot id: A0A3Q2QCV0
names: Similarity
messages: Belongs to the YOS1 family.

8078:prkacaa
gene id: 8078:prkacaa
uniprot id: A0A146W7X3
uniprot id: A0A146ZZB9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

8078:sfrp1a
gene id: 8078:sfrp1a
uniprot id: A0A3Q2Q4F2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:dnase1l1
gene id: 8078:dnase1l1
uniprot id: A0A146VGC3
names: Similarity
messages: Belongs to the DNase I family.

8078:zic2a
gene id: 8078:zic2a
uniprot id: A0A3Q2PAF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

8078:anpepa
gene id: 8078:anpepa
uniprot id: A0A3Q2PZH2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8078:tmem244
gene id: 8078:tmem244
uniprot id: A0A3Q2TQU4
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105932522
gene id: 8078:LOC105932522
uniprot id: A0A3Q2PUT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

8078:LOC105939188
gene id: 8078:LOC105939188
uniprot id: A0A3Q2QBP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:slx1b
gene id: 8078:slx1b
uniprot id: A0A3Q2Q3U4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:scamp3
gene id: 8078:scamp3
uniprot id: A0A146P7R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8078:LOC105934584
gene id: 8078:LOC105934584
uniprot id: A0A146P638
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

8078:LOC105937633
gene id: 8078:LOC105937633
uniprot id: A0A3Q2PXT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

8078:tatdn1
gene id: 8078:tatdn1
uniprot id: A0A3Q2PDX3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

8078:cnep1r1
gene id: 8078:cnep1r1
uniprot id: A0A3Q2QNH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNEP1R1 family.
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane

8078:LOC105916833
gene id: 8078:LOC105916833
uniprot id: A0A3Q2PVB1
names: Similarity
messages: Belongs to the peptidase C19 family.

8078:LOC105926025
gene id: 8078:LOC105926025
uniprot id: A0A3Q2P027
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

8078:mtmr9
gene id: 8078:mtmr9
uniprot id: A0A3Q2TLH1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8078:LOC105931906
gene id: 8078:LOC105931906
uniprot id: A0A3Q2QZ30
names: Similarity
messages: Belongs to the peptidase C1 family.

8078:si:ch73-141c7.1
gene id: 8078:si:ch73-141c7.1
uniprot id: A0A3Q2QL73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

8078:mfsd9
gene id: 8078:mfsd9
uniprot id: A0A3Q2PFA8
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105936134
gene id: 8078:LOC105936134
uniprot id: A0A146ZSC2
names: Similarity
messages: Belongs to the DDIT4 family.

8078:LOC105938399
gene id: 8078:LOC105938399
uniprot id: A0A146V5A7
names: Similarity
messages: Belongs to the MAX family.

8078:LOC105933411
gene id: 8078:LOC105933411
uniprot id: A0A3Q2QEY0
uniprot id: A0A3Q2QFH7
uniprot id: A0A3Q2T129
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

8078:LOC105920662
gene id: 8078:LOC105920662
uniprot id: A0A146RPX8
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105933989
gene id: 8078:LOC105933989
uniprot id: A0A3Q2TM50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8078:LOC105934524
gene id: 8078:LOC105934524
uniprot id: A0A146ZUE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

8078:ralba
gene id: 8078:ralba
uniprot id: A0A3Q2P388
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8078:LOC105921487
gene id: 8078:LOC105921487
uniprot id: A0A147ALW8
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8078:zdhhc13
gene id: 8078:zdhhc13
uniprot id: A0A3Q2R1V7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8078:rpl6
gene id: 8078:rpl6
uniprot id: A0A3Q2P6B3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

8078:LOC105934899
gene id: 8078:LOC105934899
uniprot id: A0A3Q2PRJ8
uniprot id: A0A3Q2TIM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:mfsd6l
gene id: 8078:mfsd6l
uniprot id: A0A147A4E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

8078:LOC105928557
gene id: 8078:LOC105928557
uniprot id: A0A3Q2QC17
names: Similarity
messages: Belongs to the TAFA family.

8078:pla2g12a
gene id: 8078:pla2g12a
uniprot id: A0A3Q2QER2
names: Subcellular Location Annotation
messages: Secreted

8078:mrps12
gene id: 8078:mrps12
uniprot id: A0A3Q2QBH3
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

8078:tjp3
gene id: 8078:tjp3
uniprot id: A0A3Q2TUC8
names: Similarity
messages: Belongs to the MAGUK family.

8078:LOC105937289
gene id: 8078:LOC105937289
uniprot id: A0A3Q2NP39
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:cbfb
gene id: 8078:cbfb
uniprot id: A0A146XUM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

8078:LOC105927988
gene id: 8078:LOC105927988
uniprot id: A0A3Q2PU10
uniprot id: A0A3Q2PU90
names: Similarity
messages: Belongs to the copine family.

8078:LOC105917696
gene id: 8078:LOC105917696
uniprot id: A0A146Z8Q4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

8078:ptpn11b
gene id: 8078:ptpn11b
uniprot id: A0A3Q2PCP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

8078:LOC105930482
gene id: 8078:LOC105930482
uniprot id: Q9YI64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8078:LOC105936275
gene id: 8078:LOC105936275
uniprot id: A0A3Q2P1B7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:malt3
gene id: 8078:malt3
uniprot id: A0A3Q2SQV8
names: Subcellular Location Annotation
messages: Membrane

8078:rps27a
gene id: 8078:rps27a
uniprot id: A0A3Q2SNM2
names: Similarity
names: Subunit
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Ribosomal protein S27a is part of the 40S ribosomal subunit.

8078:rpl5a
gene id: 8078:rpl5a
uniprot id: A0A146XXG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

8078:LOC105931860
gene id: 8078:LOC105931860
uniprot id: A0A3Q2Q504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

8078:LOC105936748
gene id: 8078:LOC105936748
uniprot id: A0A3Q2QG14
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8078:plp1b
gene id: 8078:plp1b
uniprot id: A0A147A4K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8078:LOC105929020
gene id: 8078:LOC105929020
uniprot id: A0A3Q2TV20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

8078:LOC105930258
gene id: 8078:LOC105930258
uniprot id: A0A3Q2PUA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:abcc4
gene id: 8078:abcc4
uniprot id: A0A3Q2QR62
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Recycling endosome membrane

8078:plk4
gene id: 8078:plk4
uniprot id: A0A3Q2QH16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: centriole

8078:fto
gene id: 8078:fto
uniprot id: A0A3Q2QDU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

8078:LOC105918403
gene id: 8078:LOC105918403
uniprot id: A0A3Q2SW76
names: Similarity
messages: Belongs to the DEAD box helicase family.

8078:tpte
gene id: 8078:tpte
uniprot id: A0A3Q2PSW5
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8078:LOC105925216
gene id: 8078:LOC105925216
uniprot id: A0A3Q2QSB5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

8078:LOC105917806
gene id: 8078:LOC105917806
uniprot id: A0A3Q2P1A8
names: Subcellular Location Annotation
messages: Nucleus

8078:prpf38b
gene id: 8078:prpf38b
uniprot id: A0A3Q2NSG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

8078:LOC105931847
gene id: 8078:LOC105931847
uniprot id: A0A146NQ46
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

8078:kat6a
gene id: 8078:kat6a
uniprot id: A0A147B5J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

8078:LOC105927087
gene id: 8078:LOC105927087
uniprot id: A0A3Q2U305
names: Similarity
messages: Belongs to the CDI family.

8078:tcea3
gene id: 8078:tcea3
uniprot id: A0A3Q2PMI2
uniprot id: A0A3Q2TEE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

8078:adipor2
gene id: 8078:adipor2
uniprot id: A0A3Q2QX38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8078:cp
gene id: 8078:cp
uniprot id: A0A3Q2NSW9
names: Similarity
messages: Belongs to the multicopper oxidase family.

8078:creb1b
gene id: 8078:creb1b
uniprot id: A0A3Q2PKQ4
names: Subcellular Location Annotation
messages: Nucleus

8078:ak1
gene id: 8078:ak1
uniprot id: A0A147A1X5
uniprot id: A0A3Q2QA51
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

8078:ctss2.1
gene id: 8078:ctss2.1
uniprot id: Q6JZZ4
names: Similarity
messages: Belongs to the peptidase C1 family.

8078:psmd6
gene id: 8078:psmd6
uniprot id: A0A146P577
names: Similarity
messages: Belongs to the proteasome subunit S10 family.

8078:c1h1orf174
gene id: 8078:c1h1orf174
uniprot id: A0A146PZS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

8078:tmem265
gene id: 8078:tmem265
uniprot id: A0A147ABP5
names: Similarity
messages: Belongs to the TMEM121 family.

8078:LOC105931251
gene id: 8078:LOC105931251
uniprot id: A0A3Q2TZ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:ctsz
gene id: 8078:ctsz
uniprot id: Q6JZV5
names: Similarity
messages: Belongs to the peptidase C1 family.

8078:LOC105926021
gene id: 8078:LOC105926021
uniprot id: A0A147ABA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

8078:tlr1
gene id: 8078:tlr1
uniprot id: A0A3Q2Q1N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8078:rpl7l1
gene id: 8078:rpl7l1
uniprot id: A0A3Q2UCL3
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

8078:inka1b
gene id: 8078:inka1b
uniprot id: A0A3Q2UJ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

8078:nes
gene id: 8078:nes
uniprot id: A0A3Q2P2I9
names: Similarity
messages: Belongs to the intermediate filament family.

8078:LOC105915943
gene id: 8078:LOC105915943
uniprot id: A0A146YSF3
uniprot id: A0A147AYU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8078:cab39l
gene id: 8078:cab39l
uniprot id: A0A147AM20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

8078:soul5l
gene id: 8078:soul5l
uniprot id: A0A3Q2R0H7
names: Similarity
messages: Belongs to the HEBP family.

8078:tmem106ba
gene id: 8078:tmem106ba
uniprot id: A0A3Q2QJ90
names: Similarity
messages: Belongs to the TMEM106 family.

8078:atrn
gene id: 8078:atrn
uniprot id: A0A3Q2P4L3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:aldh3a2b
gene id: 8078:aldh3a2b
uniprot id: A0A146NI03
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8078:med27
gene id: 8078:med27
uniprot id: A0A3Q2QDZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 27 family.
messages: Nucleus

8078:armt1
gene id: 8078:armt1
uniprot id: A0A3Q2NMV9
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

8078:gnb3b
gene id: 8078:gnb3b
uniprot id: A0A3Q2NQK4
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8078:rtn2b
gene id: 8078:rtn2b
uniprot id: A0A3Q2SP20
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:mipb
gene id: 8078:mipb
uniprot id: A0A3Q2PSM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8078:LOC105933855
gene id: 8078:LOC105933855
uniprot id: A0A146SHJ7
names: Similarity
messages: Belongs to the TGF-beta family.

8078:LOC105920914
gene id: 8078:LOC105920914
uniprot id: A0A3Q2QYI8
names: Subcellular Location Annotation
messages: extracellular space

8078:LOC105929826
gene id: 8078:LOC105929826
uniprot id: A0A3Q2QSJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: extracellular matrix

8078:sting1
gene id: 8078:sting1
uniprot id: A0A147A5U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: autophagosome membrane
messages: perinuclear region

8078:fzr1b
gene id: 8078:fzr1b
uniprot id: A0A146RGT7
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

8078:tpst1
gene id: 8078:tpst1
uniprot id: A0A146NMR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

8078:slc27a4
gene id: 8078:slc27a4
uniprot id: A0A3Q2PDM3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8078:zgc:56095
gene id: 8078:zgc:56095
uniprot id: A0A3Q2NRH8
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8078:LOC105923263
gene id: 8078:LOC105923263
uniprot id: A0A3Q2QSV0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8078:derl1
gene id: 8078:derl1
uniprot id: A0A3Q2QGN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

8078:cxcl12b
gene id: 8078:cxcl12b
uniprot id: A0A3Q2UDL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

8078:loxl2b
gene id: 8078:loxl2b
uniprot id: A0A3Q2Q2P0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8078:mars2
gene id: 8078:mars2
uniprot id: A0A3Q2QP56
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8078:LOC105917275
gene id: 8078:LOC105917275
uniprot id: A0A3Q2Q6R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

8078:LOC105916230
gene id: 8078:LOC105916230
uniprot id: A0A3Q2R1K5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

8078:tmem167a
gene id: 8078:tmem167a
uniprot id: A0A146P636
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

8078:scoca
gene id: 8078:scoca
uniprot id: A0A3Q2PH33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

8078:p2rx7
gene id: 8078:p2rx7
uniprot id: A0A3Q2Q1R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8078:LOC105930702
gene id: 8078:LOC105930702
uniprot id: A0A3Q2TQR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:gh1
gene id: 8078:gh1
uniprot id: A0A3Q2P838
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

8078:spry2
gene id: 8078:spry2
uniprot id: A0A3Q2QZJ9
names: Similarity
messages: Belongs to the sprouty family.

8078:gcdhb
gene id: 8078:gcdhb
uniprot id: A0A3Q2QGG5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8078:LOC105917687
gene id: 8078:LOC105917687
uniprot id: A0A3Q2T539
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8078:tarbp2
gene id: 8078:tarbp2
uniprot id: A0A3Q2QSA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC.

8078:adcy9
gene id: 8078:adcy9
uniprot id: A0A3Q2T7E0
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

8078:gpr182
gene id: 8078:gpr182
uniprot id: A0A147B3H8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:strn4
gene id: 8078:strn4
uniprot id: A0A3Q2UJE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

8078:dus3l
gene id: 8078:dus3l
uniprot id: A0A3Q2P8R2
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

8078:LOC105918373
gene id: 8078:LOC105918373
uniprot id: A0A3Q2NZF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

8078:sigirr
gene id: 8078:sigirr
uniprot id: A0A3Q2QMY1
uniprot id: A0A3Q2T7J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: Membrane

8078:ppp3cca
gene id: 8078:ppp3cca
uniprot id: A0A3Q2R2M3
uniprot id: A0A3Q2R4H3
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

8078:sirt2
gene id: 8078:sirt2
uniprot id: A0A3Q2PFP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.

8078:slc37a4a
gene id: 8078:slc37a4a
uniprot id: A0A146YRB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8078:slc7a4
gene id: 8078:slc7a4
uniprot id: A0A147ARJ7
names: Subcellular Location Annotation
messages: Membrane

8078:mnat1
gene id: 8078:mnat1
uniprot id: A0A3Q2P4C0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

8078:purbb
gene id: 8078:purbb
uniprot id: A0A146R936
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

8078:LOC105932510
gene id: 8078:LOC105932510
uniprot id: A0A3Q2PWW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

8078:si:dkey-32e23.4
gene id: 8078:si:dkey-32e23.4
uniprot id: A0A147A9N4
uniprot id: A0A3Q2TLZ5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8078:clp1
gene id: 8078:clp1
uniprot id: A0A146P766
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

8078:cga
gene id: 8078:cga
uniprot id: P47744
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer. Glycoprotein hormones are heterodimers composed of a common alpha chain described here and a unique beta chain which confers their biological specificity to the different hormones.
messages: Secreted
messages: Shared alpha chain of heterodimeric glycoprotein hormones. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. Involved in gametogenesis and steroidogenesis.

8078:sybl1
gene id: 8078:sybl1
uniprot id: A0A146MZP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8078:mical1
gene id: 8078:mical1
uniprot id: A0A3Q2TB41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

8078:LOC105939086
gene id: 8078:LOC105939086
uniprot id: A0A3Q2QFE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. SMUG1 family.
messages: Nucleus

8078:ctsba
gene id: 8078:ctsba
uniprot id: Q6XPZ9
names: Similarity
messages: Belongs to the peptidase C1 family.

8078:atp6ap1lb
gene id: 8078:atp6ap1lb
uniprot id: A0A3Q2PZX0
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

8078:zgc:163080
gene id: 8078:zgc:163080
uniprot id: A0A3Q2P6N2
names: Similarity
messages: Belongs to the TMEM14 family.

8078:coro6
gene id: 8078:coro6
uniprot id: A0A3Q2SU89
names: Similarity
messages: Belongs to the WD repeat coronin family.

8078:tnpo1
gene id: 8078:tnpo1
uniprot id: A0A3Q2QXG8
names: Subcellular Location Annotation
messages: Cytoplasm

8078:chchd4b
gene id: 8078:chchd4b
uniprot id: A0A3Q2QEZ5
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

8078:rfc2
gene id: 8078:rfc2
uniprot id: A0A3Q2QLZ9
names: Similarity
messages: Belongs to the activator 1 small subunits family.

8078:pros1
gene id: 8078:pros1
uniprot id: A0A3Q2T466
names: Caution
names: Function
messages: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105915524
gene id: 8078:LOC105915524
uniprot id: A0A3Q2Q861
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:gins2
gene id: 8078:gins2
uniprot id: A0A3Q2PZI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

8078:isl2a
gene id: 8078:isl2a
uniprot id: A0A3Q2NR45
names: Subcellular Location Annotation
messages: Nucleus

8078:nxt2
gene id: 8078:nxt2
uniprot id: A0A147A0W2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

8078:LOC105929532
gene id: 8078:LOC105929532
uniprot id: A0A3Q2NNJ3
names: Similarity
messages: Belongs to the peptidase C1 family.

8078:lzic
gene id: 8078:lzic
uniprot id: A0A146YQ74
names: Similarity
messages: Belongs to the CTNNBIP1 family.

8078:p4ha1b
gene id: 8078:p4ha1b
uniprot id: A0A3Q2Q2R7
uniprot id: A0A3Q2TVB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

8078:aph1b
gene id: 8078:aph1b
uniprot id: A0A3Q2T3X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

8078:thbs4a
gene id: 8078:thbs4a
uniprot id: A0A3Q2P046
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105934245
gene id: 8078:LOC105934245
uniprot id: A0A146ZV47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:actb1
gene id: 8078:actb1
uniprot id: A0A146ZJT9
names: Similarity
messages: Belongs to the actin family.

8078:rps6
gene id: 8078:rps6
uniprot id: A0A147AZC7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

8078:tcea2
gene id: 8078:tcea2
uniprot id: A0A3Q2PP71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

8078:LOC105916760
gene id: 8078:LOC105916760
uniprot id: A0A3Q2Q449
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8078:mat2ab
gene id: 8078:mat2ab
uniprot id: A0A3Q2QT57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

8078:LOC105939143
gene id: 8078:LOC105939143
uniprot id: A0A3Q2SXU6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

8078:bcl7a
gene id: 8078:bcl7a
uniprot id: A0A3Q2U6J8
names: Similarity
messages: Belongs to the BCL7 family.

8078:trmu
gene id: 8078:trmu
uniprot id: A0A146ZQU8
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

8078:mark3a
gene id: 8078:mark3a
uniprot id: A0A3Q2P9T8
uniprot id: A0A3Q2QIU0
uniprot id: A0A3Q2QKR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

8078:mustn1a
gene id: 8078:mustn1a
uniprot id: A0A3Q2P2J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

8078:LOC105923499
gene id: 8078:LOC105923499
uniprot id: A0A3Q2TEQ5
names: Subcellular Location Annotation
messages: Z line

8078:foxf2a
gene id: 8078:foxf2a
uniprot id: A0A3Q2PL71
names: Subcellular Location Annotation
messages: Nucleus

8078:oat
gene id: 8078:oat
uniprot id: A0A3Q2UC13
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

8078:rdh14b
gene id: 8078:rdh14b
uniprot id: A0A3Q2QT42
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:ykt6
gene id: 8078:ykt6
uniprot id: A0A3Q2U557
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

8078:klhl36
gene id: 8078:klhl36
uniprot id: A0A3Q2P6M6
names: Function
messages: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

8078:tspy
gene id: 8078:tspy
uniprot id: A0A146ZU14
uniprot id: A0A3Q2UPJ5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

8078:e2f2
gene id: 8078:e2f2
uniprot id: A0A3Q2P2A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8078:eif1
gene id: 8078:eif1
uniprot id: A0A3Q2Q1L6
names: Similarity
messages: Belongs to the SUI1 family.

8078:si:dkey-246g23.4
gene id: 8078:si:dkey-246g23.4
uniprot id: A0A3Q2QDE6
names: Subcellular Location Annotation
messages: Membrane

8078:tprg1l
gene id: 8078:tprg1l
uniprot id: A0A146S572
names: Similarity
messages: Belongs to the TPRG1 family.

8078:si:dkey-172j4.3
gene id: 8078:si:dkey-172j4.3
uniprot id: A0A3Q2NSP3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8078:zgc:154006
gene id: 8078:zgc:154006
uniprot id: A0A3Q2U3N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

8078:sntb2
gene id: 8078:sntb2
uniprot id: A0A3Q2QYY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

8078:foxi3b
gene id: 8078:foxi3b
uniprot id: A0A3Q2T5S6
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105918004
gene id: 8078:LOC105918004
uniprot id: A0A3Q2PZ28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

8078:fn3krp
gene id: 8078:fn3krp
uniprot id: A0A3Q2QP57
names: Similarity
messages: Belongs to the fructosamine kinase family.

8078:LOC105917430
gene id: 8078:LOC105917430
uniprot id: A0A3Q2TKM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

8078:mxra5a
gene id: 8078:mxra5a
uniprot id: A0A146Y926
names: Subcellular Location Annotation
messages: Membrane

8078:vps33a
gene id: 8078:vps33a
uniprot id: A0A146P4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8078:atp1b3a
gene id: 8078:atp1b3a
uniprot id: A0A3Q2THK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8078:LOC105915284
gene id: 8078:LOC105915284
uniprot id: A0A3Q2PHJ4
names: Similarity
messages: Belongs to the SPSB family.

8078:eif1ad
gene id: 8078:eif1ad
uniprot id: A0A3Q2PQD9
names: Similarity
messages: Belongs to the EIF1AD family.

8078:slc25a39
gene id: 8078:slc25a39
uniprot id: A0A3Q2SXX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:apoa4a
gene id: 8078:apoa4a
uniprot id: A0A3Q2QQX4
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8078:trmt5
gene id: 8078:trmt5
uniprot id: A0A3Q2QFY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

8078:grk1a
gene id: 8078:grk1a
uniprot id: A0A3Q2P8H3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8078:draxin
gene id: 8078:draxin
uniprot id: A0A146ZLC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord.
messages: Secreted

8078:LOC105918867
gene id: 8078:LOC105918867
uniprot id: A0A3Q2P3E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:cgas
gene id: 8078:cgas
uniprot id: A0A3Q2PBB4
names: Similarity
messages: Belongs to the mab-21 family.

8078:pycr1a
gene id: 8078:pycr1a
uniprot id: A0A3Q2U7N8
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

8078:cog2
gene id: 8078:cog2
uniprot id: A0A3Q2R0M6
names: Similarity
messages: Belongs to the COG2 family.

8078:rpl4
gene id: 8078:rpl4
uniprot id: A0A3Q2QAI8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

8078:slc19a1
gene id: 8078:slc19a1
uniprot id: A0A3Q2PSF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

8078:mvb12a
gene id: 8078:mvb12a
uniprot id: A0A3Q2T768
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8078:pdlim1
gene id: 8078:pdlim1
uniprot id: A0A3Q2PL45
names: Subcellular Location Annotation
messages: Z line

8078:LOC105924753
gene id: 8078:LOC105924753
uniprot id: A0A3Q2UC97
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:fgfbp3
gene id: 8078:fgfbp3
uniprot id: A0A3Q2PJD4
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

8078:olfm2a
gene id: 8078:olfm2a
uniprot id: A0A146VB06
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8078:ahdc1
gene id: 8078:ahdc1
uniprot id: A0A147B3K1
names: Subcellular Location Annotation
messages: Nucleus

8078:gata2a
gene id: 8078:gata2a
uniprot id: A0A147ABB1
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105920415
gene id: 8078:LOC105920415
uniprot id: A0A3Q2PKL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

8078:cdkl1
gene id: 8078:cdkl1
uniprot id: A0A3Q2NUG6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:mtx3
gene id: 8078:mtx3
uniprot id: A0A3Q2NZE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

8078:c12h9orf78
gene id: 8078:c12h9orf78
uniprot id: A0A3Q2R042
names: Similarity
messages: Belongs to the TLS1 family.

8078:neu4
gene id: 8078:neu4
uniprot id: A0A3Q2SWZ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8078:gck
gene id: 8078:gck
uniprot id: A0A3Q2SYF3
names: Similarity
messages: Belongs to the hexokinase family.

8078:fam114a1
gene id: 8078:fam114a1
uniprot id: A0A3Q2QGP5
names: Similarity
messages: Belongs to the FAM114 family.

8078:pgk1
gene id: 8078:pgk1
uniprot id: A0A146P6J4
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

8078:alg3
gene id: 8078:alg3
uniprot id: A0A3Q2PWN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Belongs to the glycosyltransferase 58 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:stx2b
gene id: 8078:stx2b
uniprot id: A0A3Q2NP15
names: Similarity
messages: Belongs to the syntaxin family.

8078:glb1l
gene id: 8078:glb1l
uniprot id: A0A146NKP0
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

8078:si:ch73-21k16.5
gene id: 8078:si:ch73-21k16.5
uniprot id: A0A3Q2P6Q2
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

8078:LOC105936347
gene id: 8078:LOC105936347
uniprot id: A0A146ZQQ6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

8078:tmem87b
gene id: 8078:tmem87b
uniprot id: A0A3Q2U3Y1
names: Subcellular Location Annotation
messages: Membrane

8078:gtf2h5
gene id: 8078:gtf2h5
uniprot id: A0A3Q2TW99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

8078:chst3a
gene id: 8078:chst3a
uniprot id: A0A3Q2Q2Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8078:grcc10
gene id: 8078:grcc10
uniprot id: A0A146ZLC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

8078:mmp23bb
gene id: 8078:mmp23bb
uniprot id: A0A147AMC9
names: Caution
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105932499
gene id: 8078:LOC105932499
uniprot id: A0A146ZZN3
names: Subcellular Location Annotation
messages: Nucleus

8078:pgm5
gene id: 8078:pgm5
uniprot id: A0A3Q2THA2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8078:suclg1
gene id: 8078:suclg1
uniprot id: A0A146VEF5
uniprot id: A0A3Q2T098
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

8078:sfxn5b
gene id: 8078:sfxn5b
uniprot id: A0A3Q2NTV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

8078:ptgesl
gene id: 8078:ptgesl
uniprot id: A0A3Q2PD29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

8078:vgll2b
gene id: 8078:vgll2b
uniprot id: A0A3Q2P1P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

8078:yod1
gene id: 8078:yod1
uniprot id: A0A3Q2T977
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Cleaves both polyubiquitin and di-ubiquitin.

8078:smarca2
gene id: 8078:smarca2
uniprot id: A0A3Q2Q043
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8078:LOC105938015
gene id: 8078:LOC105938015
uniprot id: A0A3Q2P280
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:tmem30c
gene id: 8078:tmem30c
uniprot id: A0A3Q2PD34
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

8078:gsk3ba
gene id: 8078:gsk3ba
uniprot id: A0A3Q2QV75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Cytoplasm
messages: Nucleus

8078:LOC105937308
gene id: 8078:LOC105937308
uniprot id: A0A3Q2Q6E5
names: Similarity
messages: Belongs to the globin family.

8078:dnase2
gene id: 8078:dnase2
uniprot id: A0A3Q2TBG0
names: Similarity
messages: Belongs to the DNase II family.

8078:pex1
gene id: 8078:pex1
uniprot id: A0A3Q2QG12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

8078:trim33
gene id: 8078:trim33
uniprot id: A0A3Q2QLJ7
names: Subcellular Location Annotation
messages: Membrane

8078:gphnb
gene id: 8078:gphnb
uniprot id: A0A3Q2SSY4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

8078:metrnla
gene id: 8078:metrnla
uniprot id: A0A3Q2PHS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the meteorin family.
messages: Secreted

8078:atp2a2b
gene id: 8078:atp2a2b
uniprot id: A0A146P484
uniprot id: A0A3Q2P9R6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8078:cep63
gene id: 8078:cep63
uniprot id: A0A147ACG0
names: Similarity
messages: Belongs to the CEP63 family.

8078:pcna
gene id: 8078:pcna
uniprot id: A0A147A0R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

8078:LOC105927866
gene id: 8078:LOC105927866
uniprot id: A0A3Q2Q4G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

8078:golt1bb
gene id: 8078:golt1bb
uniprot id: A0A3Q2SYK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

8078:tagln
gene id: 8078:tagln
uniprot id: A0A3Q2PQE3
names: Similarity
messages: Belongs to the calponin family.

8078:nr3c1
gene id: 8078:nr3c1
uniprot id: A0A147B5Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

8078:tmem59l
gene id: 8078:tmem59l
uniprot id: A0A3Q2TY36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:LOC105939221
gene id: 8078:LOC105939221
uniprot id: C1K0Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8078:cav1
gene id: 8078:cav1
uniprot id: A0A3Q2T470
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

8078:trmt61a
gene id: 8078:trmt61a
uniprot id: A0A146NL90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

8078:ppm1bb
gene id: 8078:ppm1bb
uniprot id: A0A3Q2QDV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8078:grnb
gene id: 8078:grnb
uniprot id: A0A3Q2P8Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8078:LOC105919991
gene id: 8078:LOC105919991
uniprot id: A0A146QPL0
names: Subcellular Location Annotation
messages: Nucleus

8078:mark1
gene id: 8078:mark1
uniprot id: A0A3Q2Q276
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

8078:nploc4
gene id: 8078:nploc4
uniprot id: A0A146Q1K8
names: Similarity
messages: Belongs to the NPL4 family.

8078:dtnbp1b
gene id: 8078:dtnbp1b
uniprot id: A0A3Q2TML6
uniprot id: A0A3Q2TML9
names: Similarity
messages: Belongs to the dysbindin family.

8078:glra2
gene id: 8078:glra2
uniprot id: A0A146ZWA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

8078:itga8
gene id: 8078:itga8
uniprot id: A0A3Q2UKC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8078:LOC105933883
gene id: 8078:LOC105933883
uniprot id: A0A3Q2P0A7
names: Similarity
messages: Belongs to the peptidase C15 family.

8078:chac1
gene id: 8078:chac1
uniprot id: A0A3Q2UNC7
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

8078:acad9
gene id: 8078:acad9
uniprot id: A0A3Q2PEF5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8078:gdpd1
gene id: 8078:gdpd1
uniprot id: A0A3Q2NS06
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8078:six2a
gene id: 8078:six2a
uniprot id: A0A147A7G7
names: Subcellular Location Annotation
messages: Nucleus

8078:srp54
gene id: 8078:srp54
uniprot id: A0A3Q2Q8R7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Nucleus speckle
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

8078:tshz3b
gene id: 8078:tshz3b
uniprot id: A0A147AC18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

8078:ing3
gene id: 8078:ing3
uniprot id: A0A146PHD6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8078:tmem168b
gene id: 8078:tmem168b
uniprot id: A0A3Q2QRP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane

8078:ap3m2
gene id: 8078:ap3m2
uniprot id: A0A146NWC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus

8078:stmn1b
gene id: 8078:stmn1b
uniprot id: A0A3Q2PUE4
names: Similarity
messages: Belongs to the stathmin family.

8078:atp2a1l
gene id: 8078:atp2a1l
uniprot id: A0A3Q2U9F8
uniprot id: A0A3Q2U9G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8078:nudt19
gene id: 8078:nudt19
uniprot id: A0A3Q2P5N7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

8078:cdk4
gene id: 8078:cdk4
uniprot id: A0A3Q2P520
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:sin3b
gene id: 8078:sin3b
uniprot id: A0A3Q2NXU6
names: Subcellular Location Annotation
messages: Nucleus

8078:lamtor1
gene id: 8078:lamtor1
uniprot id: A0A3Q2Q932
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8078:cplx4a
gene id: 8078:cplx4a
uniprot id: A0A147A252
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8078:myog
gene id: 8078:myog
uniprot id: A0A3Q2R019
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8078:si:dkey-174m14.3
gene id: 8078:si:dkey-174m14.3
uniprot id: A0A3Q2PKM8
names: Subcellular Location Annotation
messages: Membrane

8078:tp53i11b
gene id: 8078:tp53i11b
uniprot id: A0A3Q2QFS6
names: Subcellular Location Annotation
messages: Membrane

8078:slc6a4a
gene id: 8078:slc6a4a
uniprot id: A0A3Q2NN97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8078:gk5
gene id: 8078:gk5
uniprot id: A0A3Q2PRH5
names: Similarity
messages: Belongs to the FGGY kinase family.

8078:rps15a
gene id: 8078:rps15a
uniprot id: A0A3Q2PMQ2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.

8078:clu
gene id: 8078:clu
uniprot id: A0A3Q2PMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus
messages: Secreted
messages: chromaffin granule
messages: cytosol

8078:snx18a
gene id: 8078:snx18a
uniprot id: A0A3Q2NZ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8078:lpar3
gene id: 8078:lpar3
uniprot id: A0A3Q2QQ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

8078:oprk1
gene id: 8078:oprk1
uniprot id: A0A3Q2PNX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:bbs2
gene id: 8078:bbs2
uniprot id: A0A146XU34
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

8078:apaf1
gene id: 8078:apaf1
uniprot id: A0A3Q2U2C5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Monomer. Oligomerizes upon binding of cytochrome c and dATP.
messages: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

8078:LOC105933241
gene id: 8078:LOC105933241
uniprot id: A0A3Q2QQB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8078:vps54
gene id: 8078:vps54
uniprot id: A0A3Q2Q739
names: Similarity
messages: Belongs to the VPS54 family.

8078:LOC105928871
gene id: 8078:LOC105928871
uniprot id: Q9PVI0
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:LOC105918655
gene id: 8078:LOC105918655
uniprot id: A0A3Q2UIG9
names: Similarity
messages: Belongs to the peptidase C14A family.

8078:rad21l1
gene id: 8078:rad21l1
uniprot id: A0A3Q2R326
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

8078:psmb8a
gene id: 8078:psmb8a
uniprot id: A0A3Q2PC00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8078:grhl1
gene id: 8078:grhl1
uniprot id: A0A3Q2P1N7
names: Subcellular Location Annotation
messages: Nucleus

8078:cd79b
gene id: 8078:cd79b
uniprot id: A0A146ZMN3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:LOC105938446
gene id: 8078:LOC105938446
uniprot id: A0A3Q2QNI7
names: Similarity
messages: Belongs to the GORASP family.

8078:LOC105932500
gene id: 8078:LOC105932500
uniprot id: A0A146W238
names: Subcellular Location Annotation
messages: cytoskeleton

8078:sh3bp5b
gene id: 8078:sh3bp5b
uniprot id: A0A3Q2PQB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

8078:plpp1a
gene id: 8078:plpp1a
uniprot id: A0A3Q2Q4U9
uniprot id: A0A3Q2UQY7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: caveola

8078:slc25a19
gene id: 8078:slc25a19
uniprot id: A0A3Q2TZH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:LOC105934102
gene id: 8078:LOC105934102
uniprot id: A0A3Q2TYA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

8078:fam168a
gene id: 8078:fam168a
uniprot id: A0A147AHB0
names: Similarity
messages: Belongs to the FAM168 family.

8078:ptger1a
gene id: 8078:ptger1a
uniprot id: A0A147A0I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:pex14
gene id: 8078:pex14
uniprot id: A0A3Q2PA78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

8078:LOC105930534
gene id: 8078:LOC105930534
uniprot id: A0A146WD25
names: Similarity
messages: Belongs to the TPD52 family.

8078:dnajb12b
gene id: 8078:dnajb12b
uniprot id: A0A3Q2QLY9
names: Subcellular Location Annotation
messages: Membrane

8078:zmp:0000001236
gene id: 8078:zmp:0000001236
uniprot id: A0A146ZUH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

8078:nab2
gene id: 8078:nab2
uniprot id: A0A3Q2QCM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

8078:rpl10
gene id: 8078:rpl10
uniprot id: A0A3Q2T6H3
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

8078:fam207a
gene id: 8078:fam207a
uniprot id: A0A3Q2QS00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

8078:sec22bb
gene id: 8078:sec22bb
uniprot id: A0A3Q2TY02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8078:elavl1a
gene id: 8078:elavl1a
uniprot id: A0A146NU63
names: Similarity
messages: Belongs to the RRM elav family.

8078:abitram
gene id: 8078:abitram
uniprot id: A0A3Q2NMD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

8078:zgc:92162
gene id: 8078:zgc:92162
uniprot id: A0A146P765
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

8078:kcnab2a
gene id: 8078:kcnab2a
uniprot id: A0A146RV23
uniprot id: A0A146V050
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

8078:fabp4a
gene id: 8078:fabp4a
uniprot id: A0A3Q2PFY1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8078:htr1fa
gene id: 8078:htr1fa
uniprot id: A0A3Q2QS39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

8078:cep76
gene id: 8078:cep76
uniprot id: A0A3Q2TL62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

8078:cylda
gene id: 8078:cylda
uniprot id: A0A3Q2PFX8
uniprot id: A0A3Q2UDP0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

8078:LOC105925291
gene id: 8078:LOC105925291
uniprot id: A0A3Q2UIS5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

8078:ada2a
gene id: 8078:ada2a
uniprot id: A0A3Q2QE59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

8078:gnrh1
gene id: 8078:gnrh1
uniprot id: A4UZ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted

8078:napab
gene id: 8078:napab
uniprot id: A0A3Q2QZC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

8078:psmd5
gene id: 8078:psmd5
uniprot id: A0A3Q2T0T3
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

8078:etv4
gene id: 8078:etv4
uniprot id: A0A146V8C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8078:gas6
gene id: 8078:gas6
uniprot id: A0A3Q2P8N8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105916568
gene id: 8078:LOC105916568
uniprot id: A0A3Q2QIF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

8078:rabep1
gene id: 8078:rabep1
uniprot id: A0A3Q2Q3Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

8078:LOC105938063
gene id: 8078:LOC105938063
uniprot id: A0A3Q2QDC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:cfap53
gene id: 8078:cfap53
uniprot id: A0A3Q2P1D7
names: Similarity
messages: Belongs to the CFAP53 family.

8078:castor1
gene id: 8078:castor1
uniprot id: A0A3Q2NW40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GATS family.
messages: cytosol

8078:LOC105917678
gene id: 8078:LOC105917678
uniprot id: A0A3Q2SXQ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8078:hbs1l
gene id: 8078:hbs1l
uniprot id: A0A146P493
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Interacts with the SKI complex.

8078:cchcr1
gene id: 8078:cchcr1
uniprot id: A0A3Q2TXV1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a regulator of keratinocyte proliferation or differentiation.
messages: Nucleus

8078:zdhhc24
gene id: 8078:zdhhc24
uniprot id: A0A3Q2Q7Y3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8078:slc25a1a
gene id: 8078:slc25a1a
uniprot id: A0A3Q2QUP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:cep19
gene id: 8078:cep19
uniprot id: A0A3Q2Q5I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

8078:LOC105917082
gene id: 8078:LOC105917082
uniprot id: A0A3Q2QV46
names: Similarity
messages: Belongs to the IFT43 family.

8078:LOC105934014
gene id: 8078:LOC105934014
uniprot id: A0A146P5W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:mid2
gene id: 8078:mid2
uniprot id: A0A147A6V7
names: Subcellular Location Annotation
messages: cytoskeleton

8078:ergic1
gene id: 8078:ergic1
uniprot id: A0A146NWC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8078:sar1ab
gene id: 8078:sar1ab
uniprot id: A0A3Q2R131
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

8078:rps20
gene id: 8078:rps20
uniprot id: A0A3Q2QZC1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

8078:prickle3
gene id: 8078:prickle3
uniprot id: A0A146ZU02
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

8078:LOC105916803
gene id: 8078:LOC105916803
uniprot id: A0A3Q2PZM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8078:LOC105930637
gene id: 8078:LOC105930637
uniprot id: A0A147A2B9
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:adcyap1a
gene id: 8078:adcyap1a
uniprot id: A0A3Q2T7V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8078:si:dkey-91m11.5
gene id: 8078:si:dkey-91m11.5
uniprot id: A0A3Q2NYK3
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

8078:LOC105929264
gene id: 8078:LOC105929264
uniprot id: A0A146QNH5
uniprot id: A0A3Q2PBC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: cytoskeleton

8078:arpc1b
gene id: 8078:arpc1b
uniprot id: A0A146UVS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

8078:ano10a
gene id: 8078:ano10a
uniprot id: A0A3Q2SZJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

8078:kcnk13b
gene id: 8078:kcnk13b
uniprot id: A0A3Q2NX72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8078:aff4
gene id: 8078:aff4
uniprot id: A0A146VKL2
names: Similarity
messages: Belongs to the AF4 family.

8078:reln
gene id: 8078:reln
uniprot id: A0A146P1Y2
uniprot id: A0A146PFF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reelin family.
messages: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Oligomer of disulfide-linked homodimers. Binds to the ectodomains of VLDLR and LRP8/APOER2.
messages: extracellular matrix

8078:c6
gene id: 8078:c6
uniprot id: A0A3Q2QQI5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:LOC105933357
gene id: 8078:LOC105933357
uniprot id: A0A3Q2QME2
names: Similarity
messages: Belongs to the COX20 family.

8078:LOC105924328
gene id: 8078:LOC105924328
uniprot id: A0A3Q2NSC1
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Cell membrane
messages: Homodimer.
messages: Membrane

8078:gabarapl2
gene id: 8078:gabarapl2
uniprot id: A0A3Q2R159
names: Similarity
messages: Belongs to the ATG8 family.

8078:mfsd14a2
gene id: 8078:mfsd14a2
uniprot id: A0A146NPA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8078:tnip2
gene id: 8078:tnip2
uniprot id: A0A3Q2Q751
names: Subcellular Location Annotation
messages: Cytoplasm

8078:LOC105919656
gene id: 8078:LOC105919656
uniprot id: A0A3Q2SQ00
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:psd2
gene id: 8078:psd2
uniprot id: A0A3Q2TFH0
names: Subcellular Location Annotation
messages: ruffle membrane

8078:LOC105928621
gene id: 8078:LOC105928621
uniprot id: A0A3Q2NVC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8078:si:ch1073-513e17.1
gene id: 8078:si:ch1073-513e17.1
uniprot id: A0A3Q2PLR2
names: Subcellular Location Annotation
messages: Membrane

8078:dis3l
gene id: 8078:dis3l
uniprot id: A0A3Q2Q5J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family.
messages: Cytoplasm

8078:tmem97
gene id: 8078:tmem97
uniprot id: A0A3Q2Q639
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM97/sigma-2 receptor family.
messages: Endoplasmic reticulum membrane
messages: Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

8078:srprb
gene id: 8078:srprb
uniprot id: A0A3Q2U3Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:fgd4a
gene id: 8078:fgd4a
uniprot id: A0A3Q2NZK2
uniprot id: A0A3Q2SWV6
names: Subcellular Location Annotation
messages: cytoskeleton

8078:LOC105916681
gene id: 8078:LOC105916681
uniprot id: A0A3Q2P0C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8078:LOC105926927
gene id: 8078:LOC105926927
uniprot id: A0A146P2E8
uniprot id: A0A3Q2PE11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

8078:LOC105937269
gene id: 8078:LOC105937269
uniprot id: A0A3Q2Q804
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

8078:LOC105939283
gene id: 8078:LOC105939283
uniprot id: A0A3Q2Q4X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Secreted

8078:msi1b
gene id: 8078:msi1b
uniprot id: A0A147AVZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

8078:bmp3
gene id: 8078:bmp3
uniprot id: A0A146WSG6
names: Similarity
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.

8078:ptgis
gene id: 8078:ptgis
uniprot id: A0A3Q2PG91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8078:elovl1b
gene id: 8078:elovl1b
uniprot id: A0A3Q2Q4V6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

8078:irf8
gene id: 8078:irf8
uniprot id: A0A3Q2R2L4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8078:ddx55
gene id: 8078:ddx55
uniprot id: A0A146WD70
names: Similarity
messages: Belongs to the DEAD box helicase family.

8078:akap8l
gene id: 8078:akap8l
uniprot id: A0A3Q2QYF8
names: Similarity
messages: Belongs to the AKAP95 family.

8078:vps37ba
gene id: 8078:vps37ba
uniprot id: A0A3Q2TVS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

8078:cmc4
gene id: 8078:cmc4
uniprot id: A0A3Q2NPG6
names: Similarity
messages: Belongs to the CMC4 family.

8078:cnot11
gene id: 8078:cnot11
uniprot id: A0A3Q2NPR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

8078:eogt
gene id: 8078:eogt
uniprot id: A0A147AC60
names: Similarity
messages: Belongs to the glycosyltransferase 61 family.

8078:emc2
gene id: 8078:emc2
uniprot id: A0A3Q2P692
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

8078:colgalt1b
gene id: 8078:colgalt1b
uniprot id: A0A3Q2QKM6
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

8078:zgc:153733
gene id: 8078:zgc:153733
uniprot id: A0A3Q2QK62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

8078:tapt1a
gene id: 8078:tapt1a
uniprot id: A0A3Q2QZF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

8078:si:ch211-236l14.4
gene id: 8078:si:ch211-236l14.4
uniprot id: A0A147AU69
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

8078:gins4
gene id: 8078:gins4
uniprot id: A0A3Q2QYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

8078:nit2
gene id: 8078:nit2
uniprot id: A0A147ACM6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

8078:tyms
gene id: 8078:tyms
uniprot id: A0A147AUQ4
names: Similarity
messages: Belongs to the thymidylate synthase family.

8078:sdc3
gene id: 8078:sdc3
uniprot id: A0A3Q2P3J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

8078:LOC105927340
gene id: 8078:LOC105927340
uniprot id: A0A3Q2QFR6
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

8078:bcr
gene id: 8078:bcr
uniprot id: A0A3Q2PBR3
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

8078:ifrd2
gene id: 8078:ifrd2
uniprot id: A0A3Q2ULM0
names: Similarity
messages: Belongs to the IFRD family.

8078:LOC105917967
gene id: 8078:LOC105917967
uniprot id: A0A147AVU1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8078:grem2a
gene id: 8078:grem2a
uniprot id: A0A3Q2R2J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

8078:mrpl47
gene id: 8078:mrpl47
uniprot id: A0A146ZPV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

8078:LOC105916613
gene id: 8078:LOC105916613
uniprot id: A0A146PZT9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8078:sec61b
gene id: 8078:sec61b
uniprot id: A0A3Q2UH04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

8078:LOC105932779
gene id: 8078:LOC105932779
uniprot id: A0A146QK65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8078:gpr184
gene id: 8078:gpr184
uniprot id: A0A3Q2PMD4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:pofut1
gene id: 8078:pofut1
uniprot id: A0A146P4I9
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

8078:nup85
gene id: 8078:nup85
uniprot id: A0A3Q2Q6M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

8078:igfbp5a
gene id: 8078:igfbp5a
uniprot id: A0A147B407
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:psat1
gene id: 8078:psat1
uniprot id: A0A3Q2NWM2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

8078:fgf16
gene id: 8078:fgf16
uniprot id: A0A3Q2QLD9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8078:tlr3
gene id: 8078:tlr3
uniprot id: A0A3Q2QSE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8078:me1
gene id: 8078:me1
uniprot id: A0A3Q2P7S3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

8078:bcat2
gene id: 8078:bcat2
uniprot id: A0A147AXL3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

8078:epha4l
gene id: 8078:epha4l
uniprot id: A0A3Q2PZK5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8078:ldhd
gene id: 8078:ldhd
uniprot id: A0A147A4B4
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

8078:LOC105930570
gene id: 8078:LOC105930570
uniprot id: Q2I6X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8078:prkcea
gene id: 8078:prkcea
uniprot id: A0A147ASQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

8078:LOC105928211
gene id: 8078:LOC105928211
uniprot id: A0A146P3X1
names: Similarity
messages: Belongs to the EPS8 family.

8078:slc30a9
gene id: 8078:slc30a9
uniprot id: A0A3Q2TZT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Membrane
messages: Nucleus
messages: Vesicle

8078:foxo1a
gene id: 8078:foxo1a
uniprot id: A0A3Q2PGD9
names: Subcellular Location Annotation
messages: Nucleus

8078:pde5ab
gene id: 8078:pde5ab
uniprot id: A0A3Q2U2W9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8078:fam120b
gene id: 8078:fam120b
uniprot id: A0A3Q2PA72
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

8078:c8b
gene id: 8078:c8b
uniprot id: A0A147ACL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:LOC105915928
gene id: 8078:LOC105915928
uniprot id: A0A3Q2PJ90
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105930384
gene id: 8078:LOC105930384
uniprot id: A0A3Q2PFW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

8078:ppfibp1a
gene id: 8078:ppfibp1a
uniprot id: A0A146P6Q8
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

8078:txn
gene id: 8078:txn
uniprot id: A0A3Q2PD90
names: Similarity
messages: Belongs to the thioredoxin family.

8078:LOC105940119
gene id: 8078:LOC105940119
uniprot id: A0A146UW98
uniprot id: A0A3Q2QHB2
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:utp15
gene id: 8078:utp15
uniprot id: A0A3Q2QF08
names: Subcellular Location Annotation
messages: nucleolus

8078:LOC105927519
gene id: 8078:LOC105927519
uniprot id: A0A3Q2QRI5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

8078:LOC105933882
gene id: 8078:LOC105933882
uniprot id: A0A3Q2U4B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8078:mrpl13
gene id: 8078:mrpl13
uniprot id: A0A146NUF8
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

8078:supv3l1
gene id: 8078:supv3l1
uniprot id: A0A3Q2QKM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

8078:LOC105934247
gene id: 8078:LOC105934247
uniprot id: A0A3Q2PPV3
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

8078:tead3b
gene id: 8078:tead3b
uniprot id: A0A146WV40
uniprot id: A0A147A7C9
uniprot id: A0A3Q2PQW8
uniprot id: A0A3Q2PS97
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

8078:pkig
gene id: 8078:pkig
uniprot id: A0A3Q2PN79
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

8078:ccn2a
gene id: 8078:ccn2a
uniprot id: A0A3Q2R1V9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:nceh1a
gene id: 8078:nceh1a
uniprot id: A0A3Q2PR33
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

8078:cd28
gene id: 8078:cd28
uniprot id: A0A147AV53
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105939592
gene id: 8078:LOC105939592
uniprot id: A0A146P4S8
names: Subcellular Location Annotation
messages: Membrane

8078:thbs4b
gene id: 8078:thbs4b
uniprot id: A0A3Q2P275
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105917414
gene id: 8078:LOC105917414
uniprot id: A0A3Q2PVQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

8078:pgam2
gene id: 8078:pgam2
uniprot id: A0A147A1N1
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

8078:LOC105932102
gene id: 8078:LOC105932102
uniprot id: A0A3Q2QM15
names: Subcellular Location Annotation
messages: Secreted

8078:arf3a
gene id: 8078:arf3a
uniprot id: A0A3Q2P5I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8078:LOC105919305
gene id: 8078:LOC105919305
uniprot id: A0A3Q2UE80
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8078:arpc1a
gene id: 8078:arpc1a
uniprot id: A0A146P805
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

8078:zgc:63972
gene id: 8078:zgc:63972
uniprot id: A0A146RGJ2
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

8078:ndc80
gene id: 8078:ndc80
uniprot id: A0A3Q2PP31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

8078:LOC105935468
gene id: 8078:LOC105935468
uniprot id: A0A3Q2PH03
names: Subcellular Location Annotation
messages: Membrane

8078:man1a2
gene id: 8078:man1a2
uniprot id: A0A147AWX4
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8078:mpp5b
gene id: 8078:mpp5b
uniprot id: A0A147A267
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: tight junction

8078:uso1
gene id: 8078:uso1
uniprot id: A0A3Q2QWI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VDP/USO1/EDE1 family.
messages: Membrane

8078:nmbb
gene id: 8078:nmbb
uniprot id: A0A3Q2QLC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted

8078:eif2ak3
gene id: 8078:eif2ak3
uniprot id: A0A3Q2QF33
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

8078:KEG95 p04
gene id: 8078:KEG95_p04
uniprot id: B7U7W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

8078:dop1b
gene id: 8078:dop1b
uniprot id: A0A3Q2TIV2
names: Similarity
messages: Belongs to the dopey family.

8078:slc25a15b
gene id: 8078:slc25a15b
uniprot id: A0A146WJZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8078:phox2a
gene id: 8078:phox2a
uniprot id: A0A3Q2NSL0
names: Subcellular Location Annotation
messages: Nucleus

8078:taf6
gene id: 8078:taf6
uniprot id: A0A3Q2Q961
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

8078:ptp4a2b
gene id: 8078:ptp4a2b
uniprot id: A0A3Q2PHJ2
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8078:ppm1aa
gene id: 8078:ppm1aa
uniprot id: A0A146WXS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8078:cdk5rap1
gene id: 8078:cdk5rap1
uniprot id: A0A3Q2QVY8
names: Similarity
messages: Belongs to the methylthiotransferase family. MiaB subfamily.

8078:bnip3la
gene id: 8078:bnip3la
uniprot id: A0A3Q2NVZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

8078:hdhd3
gene id: 8078:hdhd3
uniprot id: A0A3Q2QQ19
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

8078:si:dkey-44g17.6
gene id: 8078:si:dkey-44g17.6
uniprot id: A0A3Q2UGG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8078:zdhhc21
gene id: 8078:zdhhc21
uniprot id: A0A3Q2U9M0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8078:prf1.5
gene id: 8078:prf1.5
uniprot id: A0A3Q2PEN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

8078:LOC105937778
gene id: 8078:LOC105937778
uniprot id: A0A3Q2QVX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLMP family.
messages: Lysosome membrane
messages: Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.

8078:gabra5
gene id: 8078:gabra5
uniprot id: A0A3Q2QKX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8078:cd248b
gene id: 8078:cd248b
uniprot id: A0A3Q2QZI0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:ap1g1
gene id: 8078:ap1g1
uniprot id: A0A3Q2QPD8
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8078:tmtopsb
gene id: 8078:tmtopsb
uniprot id: A0A3Q2SS79
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:cavin4b
gene id: 8078:cavin4b
uniprot id: A0A3Q2Q9G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8078:nf2b
gene id: 8078:nf2b
uniprot id: A0A3Q2NWE7
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8078:ndufaf1
gene id: 8078:ndufaf1
uniprot id: A0A3Q2Q9Q8
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

8078:LOC105922384
gene id: 8078:LOC105922384
uniprot id: A0A3Q2PKH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

8078:ptgir
gene id: 8078:ptgir
uniprot id: A0A3Q2PQ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:tfb1m
gene id: 8078:tfb1m
uniprot id: A0A3Q2T1A6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

8078:itfg1
gene id: 8078:itfg1
uniprot id: A0A3Q2Q664
names: Similarity
messages: Belongs to the TIP family.

8078:brinp1
gene id: 8078:brinp1
uniprot id: A0A3Q2NUB1
names: Similarity
messages: Belongs to the BRINP family.

8078:slc19a3a
gene id: 8078:slc19a3a
uniprot id: A0A3Q2NQX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

8078:rpl10a
gene id: 8078:rpl10a
uniprot id: A0A3Q2Q992
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

8078:pcbd1
gene id: 8078:pcbd1
uniprot id: A0A3Q2PKU3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

8078:LOC105937393
gene id: 8078:LOC105937393
uniprot id: A0A3Q2Q4U6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

8078:LOC105931926
gene id: 8078:LOC105931926
uniprot id: A0A146NMR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

8078:ppp1r16b
gene id: 8078:ppp1r16b
uniprot id: A0A3Q2PPH5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:nsun3
gene id: 8078:nsun3
uniprot id: A0A3Q2UL21
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

8078:gng10
gene id: 8078:gng10
uniprot id: A0A3Q2UR39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8078:tdo2a
gene id: 8078:tdo2a
uniprot id: A0A3Q2P3F7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:slc50a1
gene id: 8078:slc50a1
uniprot id: A0A3Q2PYE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Membrane

8078:manbal
gene id: 8078:manbal
uniprot id: A0A3Q2UE83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

8078:slc26a6l
gene id: 8078:slc26a6l
uniprot id: A0A3Q2UI71
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:slc7a6os
gene id: 8078:slc7a6os
uniprot id: A0A146YEX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

8078:fam83fa
gene id: 8078:fam83fa
uniprot id: A0A3Q2PK75
names: Similarity
messages: Belongs to the FAM83 family.

8078:LOC105935326
gene id: 8078:LOC105935326
uniprot id: A0A146VN26
uniprot id: A0A3Q2UMU7
names: Similarity
messages: Belongs to the peptidase M10A family.

8078:unc119a
gene id: 8078:unc119a
uniprot id: A0A3Q2PYD4
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8078:braf
gene id: 8078:braf
uniprot id: A0A3Q2QWP1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

8078:hs3st1l1
gene id: 8078:hs3st1l1
uniprot id: A0A147AB12
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8078:actr1
gene id: 8078:actr1
uniprot id: A0A3Q2UC61
names: Similarity
messages: Belongs to the actin family.

8078:LOC105920695
gene id: 8078:LOC105920695
uniprot id: A0A3Q2QEW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

8078:htr2aa
gene id: 8078:htr2aa
uniprot id: A0A147AVZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

8078:fam110b
gene id: 8078:fam110b
uniprot id: A0A147B0Y4
names: Similarity
messages: Belongs to the FAM110 family.

8078:cmtm3
gene id: 8078:cmtm3
uniprot id: A0A147AXZ6
names: Subcellular Location Annotation
messages: Membrane

8078:fgf14
gene id: 8078:fgf14
uniprot id: A0A147A878
uniprot id: A0A3Q2PA46
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8078:chpt1
gene id: 8078:chpt1
uniprot id: A0A3Q2Q8D9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

8078:sox10
gene id: 8078:sox10
uniprot id: A0A3Q2NYL3
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105934783
gene id: 8078:LOC105934783
uniprot id: A0A146ZTV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8078:fgf24
gene id: 8078:fgf24
uniprot id: A0A146ZZU2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8078:etfa
gene id: 8078:etfa
uniprot id: A0A3Q2TYN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

8078:polb
gene id: 8078:polb
uniprot id: A0A146P7W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

8078:LOC105931470
gene id: 8078:LOC105931470
uniprot id: A0A3Q2QRV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

8078:LOC105938941
gene id: 8078:LOC105938941
uniprot id: A0A146P4I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

8078:LOC105933181
gene id: 8078:LOC105933181
uniprot id: A0A3Q2QT07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

8078:LOC105925191
gene id: 8078:LOC105925191
uniprot id: A0A147ACR2
names: Similarity
messages: Belongs to the BRINP family.

8078:cryl1
gene id: 8078:cryl1
uniprot id: A0A3Q2UHS7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

8078:sprn
gene id: 8078:sprn
uniprot id: A0A3Q2NXD7
names: Similarity
messages: Belongs to the SPRN family.

8078:trmt44
gene id: 8078:trmt44
uniprot id: A0A146ZUE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm

8078:epha2a
gene id: 8078:epha2a
uniprot id: A0A3Q2UN38
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:rprma
gene id: 8078:rprma
uniprot id: A0A3Q2P422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reprimo family.
messages: Cytoplasm
messages: Membrane

8078:LOC105935697
gene id: 8078:LOC105935697
uniprot id: A0A3Q2Q8S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8078:pdgfc
gene id: 8078:pdgfc
uniprot id: A0A146NKX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8078:capgb
gene id: 8078:capgb
uniprot id: A0A3Q2NPY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
messages: Cytoplasm
messages: Melanosome
messages: Nucleus
messages: lamellipodium
messages: ruffle

8078:LOC105928224
gene id: 8078:LOC105928224
uniprot id: A0A3Q2PB14
uniprot id: A0A3Q2UBH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

8078:phka2
gene id: 8078:phka2
uniprot id: A0A3Q2QIM4
uniprot id: A0A3Q2QK12
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

8078:cwc25
gene id: 8078:cwc25
uniprot id: A0A3Q2NXC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

8078:ovol1a
gene id: 8078:ovol1a
uniprot id: A0A3Q2NS79
names: Subcellular Location Annotation
messages: Nucleus

8078:il2rb
gene id: 8078:il2rb
uniprot id: A0A3Q2PB56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane

8078:LOC105927313
gene id: 8078:LOC105927313
uniprot id: A0A3Q2UNB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

8078:cluha
gene id: 8078:cluha
uniprot id: A0A3Q2QZU1
uniprot id: A0A3Q2UP38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

8078:LOC105929648
gene id: 8078:LOC105929648
uniprot id: A0A3Q2PS19
names: Subcellular Location Annotation
messages: Nucleus

8078:ippk
gene id: 8078:ippk
uniprot id: A0A3Q2UL06
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

8078:agpat2
gene id: 8078:agpat2
uniprot id: A0A3Q2QC25
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

8078:zfp36l1a
gene id: 8078:zfp36l1a
uniprot id: A0A3Q2TX07
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8078:mbpa
gene id: 8078:mbpa
uniprot id: A0A3Q2PNA3
uniprot id: A0A3Q2TFT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

8078:ackr4a
gene id: 8078:ackr4a
uniprot id: A0A3Q2Q7A4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:ednrba
gene id: 8078:ednrba
uniprot id: B1PCG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:ppp2r2ba
gene id: 8078:ppp2r2ba
uniprot id: A0A146ZC00
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

8078:hoxc12a
gene id: 8078:hoxc12a
uniprot id: A0A3Q2NMK6
names: Subcellular Location Annotation
messages: Nucleus

8078:tnfsf11
gene id: 8078:tnfsf11
uniprot id: A0A3Q2Q6P2
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8078:LOC105929479
gene id: 8078:LOC105929479
uniprot id: A0A3Q2Q4W8
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105935202
gene id: 8078:LOC105935202
uniprot id: A0A3Q2QTD4
names: Subcellular Location Annotation
messages: cytoskeleton

8078:kcnk5a
gene id: 8078:kcnk5a
uniprot id: A0A3Q2P637
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8078:si:ch211-261d7.3
gene id: 8078:si:ch211-261d7.3
uniprot id: A0A3Q2NZ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

8078:rps23
gene id: 8078:rps23
uniprot id: A0A3Q2UM36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Component of the 40S small ribosomal subunit.
messages: Rough endoplasmic reticulum

8078:gpatch11
gene id: 8078:gpatch11
uniprot id: A0A3Q2UQI4
names: Similarity
messages: Belongs to the GPATCH11 family.

8078:snx10a
gene id: 8078:snx10a
uniprot id: A0A146ZUU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

8078:LOC105916581
gene id: 8078:LOC105916581
uniprot id: A0A3Q2P616
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

8078:alas1
gene id: 8078:alas1
uniprot id: A0A146MZ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

8078:LOC105931278
gene id: 8078:LOC105931278
uniprot id: A0A3Q2NQQ2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
messages: Cytoplasm
messages: Interacts with GPHN.
messages: Postsynaptic density

8078:ndufs5
gene id: 8078:ndufs5
uniprot id: A0A3Q2P3L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

8078:mcts1
gene id: 8078:mcts1
uniprot id: A0A3Q2QWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

8078:psmd11b
gene id: 8078:psmd11b
uniprot id: A0A3Q2P0C0
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

8078:c2h15orf40
gene id: 8078:c2h15orf40
uniprot id: A0A147A3X1
names: Similarity
messages: Belongs to the UPF0235 family.

8078:ccne2
gene id: 8078:ccne2
uniprot id: A0A3Q2PK71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin E subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8078:LOC105920118
gene id: 8078:LOC105920118
uniprot id: A0A3Q2QFW5
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

8078:mab21l2
gene id: 8078:mab21l2
uniprot id: A0A146RF31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mab-21 family.
messages: Cytoplasm
messages: Nucleus

8078:ercc3
gene id: 8078:ercc3
uniprot id: A0A3Q2QCB1
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

8078:LOC105916108
gene id: 8078:LOC105916108
uniprot id: A0A3Q2QHN9
names: Similarity
messages: Belongs to the TACO1 family.

8078:orai2
gene id: 8078:orai2
uniprot id: A0A3Q2TSC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

8078:LOC105937298
gene id: 8078:LOC105937298
uniprot id: A0A3Q2Q6B4
names: Similarity
messages: Belongs to the globin family.

8078:LOC105917188
gene id: 8078:LOC105917188
uniprot id: A0A3Q2P0I7
names: Subcellular Location Annotation
messages: Membrane

8078:snx8a
gene id: 8078:snx8a
uniprot id: A0A3Q2PPI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

8078:prph2b
gene id: 8078:prph2b
uniprot id: A0A3Q2NTP7
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

8078:LOC105917531
gene id: 8078:LOC105917531
uniprot id: A0A3Q2PKV1
uniprot id: A0A3Q2QQ74
names: Similarity
messages: Belongs to the zygin family.

8078:aldh4a1
gene id: 8078:aldh4a1
uniprot id: A0A146YEB9
uniprot id: A0A3Q2P1T4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8078:LOC105932154
gene id: 8078:LOC105932154
uniprot id: A0A3Q2QF71
names: Subcellular Location Annotation
messages: Nucleus

8078:tlcd2
gene id: 8078:tlcd2
uniprot id: A0A3Q2TR59
names: Subcellular Location Annotation
messages: Membrane

8078:clcn5b
gene id: 8078:clcn5b
uniprot id: A0A146VQN7
uniprot id: A0A3Q2TM97
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:dpp7
gene id: 8078:dpp7
uniprot id: A0A3Q2QC99
names: Similarity
messages: Belongs to the peptidase S28 family.

8078:tmem88b
gene id: 8078:tmem88b
uniprot id: A0A3Q2QTK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

8078:tspan3a
gene id: 8078:tspan3a
uniprot id: A0A3Q2SQN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8078:parp14rs1
gene id: 8078:parp14rs1
uniprot id: A0A3Q2QEY1
names: Similarity
messages: Belongs to the ARTD/PARP family.

8078:ndufb9
gene id: 8078:ndufb9
uniprot id: A0A3Q2PDV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8078:LOC105931336
gene id: 8078:LOC105931336
uniprot id: A0A3Q2PZX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

8078:LOC105937977
gene id: 8078:LOC105937977
uniprot id: A0A3Q2QJC9
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

8078:mef2ca
gene id: 8078:mef2ca
uniprot id: A0A3Q2Q914
names: Subcellular Location Annotation
messages: Nucleus

8078:atl3
gene id: 8078:atl3
uniprot id: A0A146P3Z3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

8078:prkaa1
gene id: 8078:prkaa1
uniprot id: A0A146P626
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

8078:lap3
gene id: 8078:lap3
uniprot id: A0A3Q2P8N2
names: Similarity
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Homohexamer.

8078:acat2
gene id: 8078:acat2
uniprot id: A0A3Q2Q501
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8078:lrrc8da
gene id: 8078:lrrc8da
uniprot id: A0A3Q2QUF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8078:atp2b2
gene id: 8078:atp2b2
uniprot id: A0A147A2M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105924278
gene id: 8078:LOC105924278
uniprot id: A0A146Z5L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8078:LOC105939466
gene id: 8078:LOC105939466
uniprot id: A0A3Q2TP60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:LOC105926996
gene id: 8078:LOC105926996
uniprot id: A0A3Q2T8M8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8078:arid1aa
gene id: 8078:arid1aa
uniprot id: A0A3Q2QTE7
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC110366376
gene id: 8078:LOC110366376
uniprot id: A0A146PAP5
names: Similarity
messages: In the C-terminal section; belongs to the OMP decarboxylase family.
messages: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

8078:LOC105933129
gene id: 8078:LOC105933129
uniprot id: A0A146ZYA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

8078:LOC105939187
gene id: 8078:LOC105939187
uniprot id: A0A3Q2Q9G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8078:ufl1
gene id: 8078:ufl1
uniprot id: A0A146P5S7
names: Similarity
messages: Belongs to the UFL1 family.

8078:pde10a
gene id: 8078:pde10a
uniprot id: A0A3Q2QBQ4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8078:LOC105927205
gene id: 8078:LOC105927205
uniprot id: A0A3Q2U1E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8078:trub1
gene id: 8078:trub1
uniprot id: A0A3Q2Q907
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

8078:etfdh
gene id: 8078:etfdh
uniprot id: A0A3Q2QWD5
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

8078:map1lc3c
gene id: 8078:map1lc3c
uniprot id: A0A3Q2TDE3
names: Similarity
messages: Belongs to the ATG8 family.

8078:lhx5
gene id: 8078:lhx5
uniprot id: A0A3Q2P0V0
names: Subcellular Location Annotation
messages: Nucleus

8078:nmd3
gene id: 8078:nmd3
uniprot id: A0A3Q2PPR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

8078:esrrb
gene id: 8078:esrrb
uniprot id: A0A146ZA46
uniprot id: A0A147B510
uniprot id: Q2I6X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8078:vwa1
gene id: 8078:vwa1
uniprot id: A0A3Q2PBD1
names: Subcellular Location Annotation
messages: Membrane
messages: basement membrane

8078:ddx6
gene id: 8078:ddx6
uniprot id: A0A3Q2R2G7
names: Similarity
messages: Belongs to the DEAD box helicase family.

8078:tefm
gene id: 8078:tefm
uniprot id: A0A3Q2U663
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEFM family.
messages: Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery.
messages: mitochondrion nucleoid

8078:luc7l3
gene id: 8078:luc7l3
uniprot id: A0A3Q2UGV3
names: Similarity
messages: Belongs to the Luc7 family.

8078:LOC105931040
gene id: 8078:LOC105931040
uniprot id: A0A3Q2QH49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8078:LOC105920296
gene id: 8078:LOC105920296
uniprot id: A0A3Q2P2H3
names: Subcellular Location Annotation
messages: Cytoplasm

8078:c1galt1b
gene id: 8078:c1galt1b
uniprot id: A0A146VCW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

8078:btk
gene id: 8078:btk
uniprot id: A0A3Q2QPN0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8078:hspa9
gene id: 8078:hspa9
uniprot id: A0A3Q2QD71
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8078:mrpl19
gene id: 8078:mrpl19
uniprot id: A0A3Q2Q3H8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

8078:ctnna1
gene id: 8078:ctnna1
uniprot id: A0A3Q2QEP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: cytoskeleton

8078:prpsap2
gene id: 8078:prpsap2
uniprot id: A0A3Q2TQL2
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

8078:tob1b
gene id: 8078:tob1b
uniprot id: A0A146P4P9
names: Similarity
messages: Belongs to the BTG family.

8078:LOC105938342
gene id: 8078:LOC105938342
uniprot id: A0A3Q2QR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

8078:ighmbp2
gene id: 8078:ighmbp2
uniprot id: A0A3Q2PZH3
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

8078:ptdss2
gene id: 8078:ptdss2
uniprot id: A0A146Z2V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

8078:c2h11orf49
gene id: 8078:c2h11orf49
uniprot id: A0A3Q2PRQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: centriolar satellite

8078:arhgef18a
gene id: 8078:arhgef18a
uniprot id: A0A3Q2P8D0
names: Subcellular Location Annotation
messages: Cytoplasm

8078:naaladl1
gene id: 8078:naaladl1
uniprot id: A0A3Q2U1Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

8078:ints2
gene id: 8078:ints2
uniprot id: A0A3Q2QT01
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

8078:LOC105934305
gene id: 8078:LOC105934305
uniprot id: A0A3Q2PJ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8078:psmb5
gene id: 8078:psmb5
uniprot id: A0A3Q2PQK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB5 displays a chymotrypsin-like activity.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8078:LOC105918414
gene id: 8078:LOC105918414
uniprot id: A0A3Q2NY36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum axoneme

8078:si:dkey-5i3.5
gene id: 8078:si:dkey-5i3.5
uniprot id: A0A3Q2SQI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

8078:si:ch211-132g1.7
gene id: 8078:si:ch211-132g1.7
uniprot id: A0A147ARU5
names: Subcellular Location Annotation
messages: Membrane

8078:mpped1
gene id: 8078:mpped1
uniprot id: A0A147B2B1
names: Similarity
messages: Belongs to the UPF0046 family.

8078:LOC105930592
gene id: 8078:LOC105930592
uniprot id: A0A3Q2SY66
names: Similarity
messages: Belongs to the TTC39 family.

8078:lsm1
gene id: 8078:lsm1
uniprot id: A0A3Q2P7I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

8078:ripor1
gene id: 8078:ripor1
uniprot id: A0A3Q2PPW0
names: Similarity
messages: Belongs to the RIPOR family.

8078:prkd3
gene id: 8078:prkd3
uniprot id: A0A3Q2P4Q1
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

8078:sgpl1
gene id: 8078:sgpl1
uniprot id: A0A3Q2PKW5
names: Similarity
messages: Belongs to the group II decarboxylase family.

8078:tgfb3
gene id: 8078:tgfb3
uniprot id: A0A3Q2PRF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

8078:eaf2
gene id: 8078:eaf2
uniprot id: A0A3Q2UIH3
names: Similarity
messages: Belongs to the EAF family.

8078:LOC105921323
gene id: 8078:LOC105921323
uniprot id: A0A3Q2R3A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

8078:itk
gene id: 8078:itk
uniprot id: A0A3Q2UQ40
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8078:stx4
gene id: 8078:stx4
uniprot id: A0A3Q2NXT3
names: Similarity
messages: Belongs to the syntaxin family.

8078:mettl26
gene id: 8078:mettl26
uniprot id: A0A3Q2TV59
names: Similarity
messages: Belongs to the UPF0585 family.

8078:mybl1
gene id: 8078:mybl1
uniprot id: A0A147B0W1
names: Subcellular Location Annotation
messages: Nucleus

8078:tgm2b
gene id: 8078:tgm2b
uniprot id: A0A3Q2QDN8
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8078:cops5
gene id: 8078:cops5
uniprot id: A0A3Q2NUQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

8078:yrk
gene id: 8078:yrk
uniprot id: A0A146Z5U2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8078:lhx9
gene id: 8078:lhx9
uniprot id: A0A3Q2NTA4
names: Subcellular Location Annotation
messages: Nucleus

8078:nr4a2a
gene id: 8078:nr4a2a
uniprot id: A0A146VTY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

8078:poglut2
gene id: 8078:poglut2
uniprot id: A0A3Q2QDY4
names: Similarity
messages: Belongs to the KDELC family.

8078:rrad
gene id: 8078:rrad
uniprot id: A0A147AY99
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

8078:crbn
gene id: 8078:crbn
uniprot id: A0A3Q2P342
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

8078:hoxa5a
gene id: 8078:hoxa5a
uniprot id: A0A3Q2QPF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8078:LOC105935457
gene id: 8078:LOC105935457
uniprot id: A0A146ZSF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

8078:lhfpl3
gene id: 8078:lhfpl3
uniprot id: A0A3Q2P2I0
names: Subcellular Location Annotation
messages: Membrane

8078:krt18a.1
gene id: 8078:krt18a.1
uniprot id: A0A3Q2PL09
names: Similarity
messages: Belongs to the intermediate filament family.

8078:cops9
gene id: 8078:cops9
uniprot id: A0A3Q2Q8H2
names: Similarity
messages: Belongs to the CSN9 family.

8078:LOC105929159
gene id: 8078:LOC105929159
uniprot id: A0A3Q2QU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8078:gmppb
gene id: 8078:gmppb
uniprot id: A0A3Q2PTV7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

8078:fap
gene id: 8078:fap
uniprot id: A0A3Q2Q462
names: Subcellular Location Annotation
messages: Cell membrane
messages: invadopodium membrane
messages: lamellipodium membrane

8078:srfb
gene id: 8078:srfb
uniprot id: A0A3Q2PK82
uniprot id: A0A3Q2PLK8
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105918555
gene id: 8078:LOC105918555
uniprot id: A0A3Q2R030
names: Subcellular Location Annotation
messages: Nucleus

8078:stom
gene id: 8078:stom
uniprot id: A0A146QWJ7
uniprot id: A0A146RVF8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8078:LOC105938058
gene id: 8078:LOC105938058
uniprot id: A0A146V742
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:LOC105918552
gene id: 8078:LOC105918552
uniprot id: A0A3Q2TNE3
names: Subcellular Location Annotation
messages: Cytoplasm

8078:mfsd10
gene id: 8078:mfsd10
uniprot id: A0A3Q2U151
names: Subcellular Location Annotation
messages: Membrane

8078:ghra
gene id: 8078:ghra
uniprot id: A0A3Q2PSH7
names: Function
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

8078:wscd2
gene id: 8078:wscd2
uniprot id: A0A3Q2QTT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Membrane

8078:tlcd3a
gene id: 8078:tlcd3a
uniprot id: A0A3Q2R1W0
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105922624
gene id: 8078:LOC105922624
uniprot id: A0A3Q2TKV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

8078:wasb
gene id: 8078:wasb
uniprot id: A0A3Q2R100
names: Subcellular Location Annotation
messages: Nucleus

8078:malt1
gene id: 8078:malt1
uniprot id: A0A146VBT2
uniprot id: A0A3Q2Q938
names: Subcellular Location Annotation
messages: Membrane

8078:mvb12bb
gene id: 8078:mvb12bb
uniprot id: A0A3Q2NPI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8078:b3gat3
gene id: 8078:b3gat3
uniprot id: A0A146Z4Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8078:nol6
gene id: 8078:nol6
uniprot id: A0A3Q2T078
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

8078:mepce
gene id: 8078:mepce
uniprot id: A0A147AR08
names: Similarity
messages: Belongs to the methyltransferase superfamily.

8078:fabp10a
gene id: 8078:fabp10a
uniprot id: Q645P9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8078:LOC105934326
gene id: 8078:LOC105934326
uniprot id: A0A146ZUX4
names: Subcellular Location Annotation
messages: Nucleus

8078:endou
gene id: 8078:endou
uniprot id: A0A3Q2PI74
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

8078:trpv6
gene id: 8078:trpv6
uniprot id: A0A3Q2PK54
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:atl2
gene id: 8078:atl2
uniprot id: A0A3Q2PWK7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

8078:dcps
gene id: 8078:dcps
uniprot id: A0A3Q2R3L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HIT family.
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.
messages: Nucleus

8078:itgb2
gene id: 8078:itgb2
uniprot id: A0A3Q2PUG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

8078:rft1
gene id: 8078:rft1
uniprot id: A0A3Q2QD81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

8078:wdr83os
gene id: 8078:wdr83os
uniprot id: A0A3Q2PFG5
names: Similarity
messages: Belongs to the Asterix family.

8078:LOC105916998
gene id: 8078:LOC105916998
uniprot id: A0A3Q2PGI4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:arsh
gene id: 8078:arsh
uniprot id: A0A3Q2QEY9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8078:fam102ba
gene id: 8078:fam102ba
uniprot id: A0A146VRW2
names: Similarity
messages: Belongs to the FAM102 family.

8078:foxd5
gene id: 8078:foxd5
uniprot id: A0A3Q2PQ80
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105936870
gene id: 8078:LOC105936870
uniprot id: A0A146ZPP1
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8078:tcirg1b
gene id: 8078:tcirg1b
uniprot id: A0A3Q2PU26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8078:cxcr2
gene id: 8078:cxcr2
uniprot id: A0A3Q2P2M3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:ppt2b
gene id: 8078:ppt2b
uniprot id: A0A147A186
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the palmitoyl-protein thioesterase family.
messages: Lysosome

8078:psph
gene id: 8078:psph
uniprot id: A0A3Q2NY01
uniprot id: A0A3Q2QAU1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

8078:acap3a
gene id: 8078:acap3a
uniprot id: A0A3Q2Q9V8
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

8078:haus3
gene id: 8078:haus3
uniprot id: A0A147ASW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

8078:sumo2b
gene id: 8078:sumo2b
uniprot id: A0A3Q2NSJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8078:pelo
gene id: 8078:pelo
uniprot id: A0A3Q2QH53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.
messages: Nucleus

8078:LOC105919053
gene id: 8078:LOC105919053
uniprot id: A0A3Q2PC94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
messages: Cytoplasm

8078:vps33b
gene id: 8078:vps33b
uniprot id: A0A3Q2PSE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8078:stard3
gene id: 8078:stard3
uniprot id: A0A3Q2PF43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8078:kcnb1
gene id: 8078:kcnb1
uniprot id: A0A146ZWY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: sarcolemma
messages: synaptosome

8078:LOC105939196
gene id: 8078:LOC105939196
uniprot id: A0A3Q2NWK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

8078:LOC105919175
gene id: 8078:LOC105919175
uniprot id: A0A147AT60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8078:LOC105920088
gene id: 8078:LOC105920088
uniprot id: A0A3Q2P5A0
names: Similarity
messages: Belongs to the FHIP family.

8078:atp6ap2
gene id: 8078:atp6ap2
uniprot id: A0A3Q2PDK0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

8078:LOC105929017
gene id: 8078:LOC105929017
uniprot id: A0A3Q2Q3H1
names: Similarity
messages: Belongs to the CRK family.

8078:hoxb6b
gene id: 8078:hoxb6b
uniprot id: A0A3Q2NYZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8078:tuba5
gene id: 8078:tuba5
uniprot id: A0A146VPF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

8078:zmp:0000000711
gene id: 8078:zmp:0000000711
uniprot id: A0A3Q2Q0E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

8078:sdf4
gene id: 8078:sdf4
uniprot id: A0A3Q2SSW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

8078:mapk8b
gene id: 8078:mapk8b
uniprot id: A0A146NNH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

8078:mocos
gene id: 8078:mocos
uniprot id: A0A3Q2QW00
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

8078:gsx1
gene id: 8078:gsx1
uniprot id: A0A3Q2PLA9
names: Subcellular Location Annotation
messages: Nucleus

8078:bmt2
gene id: 8078:bmt2
uniprot id: A0A3Q2QR53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BMT2 family.
messages: Interacts with the GATOR1 complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine. Interacts with the KICSTOR complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine.
messages: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.

8078:snrpc
gene id: 8078:snrpc
uniprot id: A0A3Q2PQH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

8078:steap3
gene id: 8078:steap3
uniprot id: A0A3Q2QXJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

8078:rdh12l
gene id: 8078:rdh12l
uniprot id: A0A3Q2NRH6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8078:scarf2
gene id: 8078:scarf2
uniprot id: A0A147A121
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:cx52.7
gene id: 8078:cx52.7
uniprot id: A0A147ASD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8078:ptger3
gene id: 8078:ptger3
uniprot id: A0A3Q2NV45
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:LOC105932800
gene id: 8078:LOC105932800
uniprot id: A0A3Q2QFY1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

8078:ptpn21
gene id: 8078:ptpn21
uniprot id: A0A3Q2TPM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

8078:elovl1a
gene id: 8078:elovl1a
uniprot id: A0A3Q2Q445
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

8078:fbxo9
gene id: 8078:fbxo9
uniprot id: A0A147AAW6
names: Subcellular Location Annotation
messages: Cytoplasm

8078:mtif3
gene id: 8078:mtif3
uniprot id: A0A3Q2PND5
names: Similarity
messages: Belongs to the IF-3 family.

8078:LOC105940222
gene id: 8078:LOC105940222
uniprot id: A0A3Q2SQ58
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

8078:mettl1
gene id: 8078:mettl1
uniprot id: A0A3Q2P4R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Nucleus

8078:csrnp3
gene id: 8078:csrnp3
uniprot id: A0A3Q2Q8N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8078:stat1a
gene id: 8078:stat1a
uniprot id: A0A3Q2QWV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8078:pfkpa
gene id: 8078:pfkpa
uniprot id: A0A3Q2PT07
uniprot id: A0A3Q2QW63
uniprot id: A0A3Q2ULL9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:atg9a
gene id: 8078:atg9a
uniprot id: A0A3Q2P7G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

8078:lsr
gene id: 8078:lsr
uniprot id: A0A146P556
names: Subcellular Location Annotation
messages: Membrane

8078:d2hgdh
gene id: 8078:d2hgdh
uniprot id: A0A3Q2QHT6
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

8078:tnfaip3
gene id: 8078:tnfaip3
uniprot id: A0A3Q2TNF5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8078:tmem231
gene id: 8078:tmem231
uniprot id: A0A3Q2QYM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

8078:actr6
gene id: 8078:actr6
uniprot id: A0A3Q2QWJ1
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.

8078:ncapg
gene id: 8078:ncapg
uniprot id: A0A3Q2P4K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

8078:psmd3
gene id: 8078:psmd3
uniprot id: A0A3Q2Q2U6
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

8078:LOC105929658
gene id: 8078:LOC105929658
uniprot id: A0A3Q2R074
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:LOC105940281
gene id: 8078:LOC105940281
uniprot id: A0A3Q2NPV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8078:ube4a
gene id: 8078:ube4a
uniprot id: A0A3Q2QCP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

8078:selenok
gene id: 8078:selenok
uniprot id: A0A3Q2TUY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein K family.
messages: Endoplasmic reticulum membrane

8078:prdm8b
gene id: 8078:prdm8b
uniprot id: A0A146WU91
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105928865
gene id: 8078:LOC105928865
uniprot id: Q9PVH9
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:LOC105932401
gene id: 8078:LOC105932401
uniprot id: A0A3Q2NNI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

8078:sf3b3
gene id: 8078:sf3b3
uniprot id: A0A3Q2QUK2
names: Subcellular Location Annotation
messages: Nucleus

8078:pim1
gene id: 8078:pim1
uniprot id: A0A3Q2QR30
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8078:chmp4ba
gene id: 8078:chmp4ba
uniprot id: A0A147ASX2
names: Similarity
messages: Belongs to the SNF7 family.

8078:ptafr
gene id: 8078:ptafr
uniprot id: A0A3Q2QCT3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

8078:coro7
gene id: 8078:coro7
uniprot id: A0A3Q2PC43
uniprot id: A0A3Q2QJF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM16/PAM16 family.
messages: Belongs to the WD repeat coronin family.
messages: Cytoplasmic vesicle
messages: F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology.
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicle
messages: cytosol
messages: trans-Golgi network

8078:zdhhc12a
gene id: 8078:zdhhc12a
uniprot id: A0A3Q2QL89
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8078:ppdpfa
gene id: 8078:ppdpfa
uniprot id: A0A3Q2NXH8
names: Similarity
messages: Belongs to the PPDPF family.

8078:tsg101a
gene id: 8078:tsg101a
uniprot id: A0A146YCZ6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

8078:dnaaf6
gene id: 8078:dnaaf6
uniprot id: A0A147AZ21
names: Similarity
messages: Belongs to the PIH1 family.

8078:scamp2
gene id: 8078:scamp2
uniprot id: A0A3Q2TJR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8078:LOC105916639
gene id: 8078:LOC105916639
uniprot id: A0A3Q2QEE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

8078:LOC105939324
gene id: 8078:LOC105939324
uniprot id: A0A146YY64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

8078:eif2d
gene id: 8078:eif2d
uniprot id: A0A3Q2NUC8
names: Similarity
messages: Belongs to the eIF2D family.

8078:eny2
gene id: 8078:eny2
uniprot id: A0A3Q2QIE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

8078:LOC105915629
gene id: 8078:LOC105915629
uniprot id: A0A3Q2R1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8078:stoml3b
gene id: 8078:stoml3b
uniprot id: A0A3Q2TK60
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8078:LOC105933313
gene id: 8078:LOC105933313
uniprot id: A0A3Q2PC79
names: Subcellular Location Annotation
messages: Nucleus

8078:fcf1
gene id: 8078:fcf1
uniprot id: A0A3Q2PT67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

8078:grb7
gene id: 8078:grb7
uniprot id: A0A3Q2UA52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

8078:smc1b
gene id: 8078:smc1b
uniprot id: A0A3Q2TN66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

8078:lmx1bb
gene id: 8078:lmx1bb
uniprot id: A0A3Q2NPE8
names: Subcellular Location Annotation
messages: Nucleus

8078:LOC105915479
gene id: 8078:LOC105915479
uniprot id: A0A3Q2SYI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8078:ccdc124
gene id: 8078:ccdc124
uniprot id: A0A3Q2PKC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CCDC124 family.
messages: Interacts with RASGEF1B.
messages: Required for proper progression of late cytokinetic stages.

8078:LOC105929394
gene id: 8078:LOC105929394
uniprot id: A0A146PJN3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:si:cabz01101003.1
gene id: 8078:si:cabz01101003.1
uniprot id: A0A3Q2PYV7
names: Subcellular Location Annotation
messages: centrosome
messages: perinuclear region

8078:atp5f1b
gene id: 8078:atp5f1b
uniprot id: A0A3Q2TAM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

8078:sept5a
gene id: 8078:sept5a
uniprot id: A0A3Q2PUH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: cytoskeleton

8078:endog
gene id: 8078:endog
uniprot id: A0A146P4M6
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

8078:gar1
gene id: 8078:gar1
uniprot id: A0A3Q2T0S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

8078:pop5
gene id: 8078:pop5
uniprot id: A0A3Q2Q3E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

8078:fam163ba
gene id: 8078:fam163ba
uniprot id: A0A3Q2T6P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

8078:LOC105934575
gene id: 8078:LOC105934575
uniprot id: A9CQK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8078:dync1li2
gene id: 8078:dync1li2
uniprot id: A0A3Q2TJJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

8078:nr2f2
gene id: 8078:nr2f2
uniprot id: A0A3Q2QBN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8078:dact1
gene id: 8078:dact1
uniprot id: A0A146ZM79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dapper family.
messages: Cytoplasm

8078:zgc:136908
gene id: 8078:zgc:136908
uniprot id: A0A146RPZ0
names: Similarity
messages: Belongs to the AAA ATPase family.

8078:gapdh
gene id: 8078:gapdh
uniprot id: A0A3Q2PFG8
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

8078:micos10
gene id: 8078:micos10
uniprot id: A0A3Q2T4Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

8078:hspb8
gene id: 8078:hspb8
uniprot id: A0A3Q2NXN6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8078:tnnt2d
gene id: 8078:tnnt2d
uniprot id: A0A3Q2QE50
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

8078:mbtps1
gene id: 8078:mbtps1
uniprot id: A0A3Q2UBJ0
names: Similarity
messages: Belongs to the peptidase S8 family.

8078:LOC105920494
gene id: 8078:LOC105920494
uniprot id: A0A3Q2UFH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Cell membrane
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8078:psma4
gene id: 8078:psma4
uniprot id: A0A146MJE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8078:LOC105916682
gene id: 8078:LOC105916682
uniprot id: A0A3Q2U3X2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8078:tmem19
gene id: 8078:tmem19
uniprot id: A0A3Q2P8A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

8078:inpp5l
gene id: 8078:inpp5l
uniprot id: A0A3Q2PX09
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

8078:rxfp3.2b
gene id: 8078:rxfp3.2b
uniprot id: A0A146QCT0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8078:LOC105921282
gene id: 8078:LOC105921282
uniprot id: A0A3Q2QFC1
names: Similarity
messages: Belongs to the ARTD/PARP family.

8078:nectin3b
gene id: 8078:nectin3b
uniprot id: A0A3Q2NP13
names: Subcellular Location Annotation
messages: Membrane

8078:pou3f2a
gene id: 8078:pou3f2a
uniprot id: A0A3Q2P6U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

8078:LOC105928868
gene id: 8078:LOC105928868
uniprot id: Q9IAX8
names: Similarity
messages: Belongs to the cytochrome P450 family.

8078:LOC105930356
gene id: 8078:LOC105930356
uniprot id: A0A3Q2PJD3
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin Y subfamily.

8078:LOC105936314
gene id: 8078:LOC105936314
uniprot id: A0A3Q2U0E5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:cdc42ep1b
gene id: 8078:cdc42ep1b
uniprot id: A0A3Q2NXU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8078:tmem45b
gene id: 8078:tmem45b
uniprot id: A0A146Y177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

8078:serinc2l
gene id: 8078:serinc2l
uniprot id: A0A147ARY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

8078:zgc:100920
gene id: 8078:zgc:100920
uniprot id: A0A146ZSU3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105938547
gene id: 8078:LOC105938547
uniprot id: A0A146V538
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8078:LOC105917184
gene id: 8078:LOC105917184
uniprot id: A0A3Q2QD93
names: Similarity
messages: Belongs to the NGF-beta family.

8078:LOC105928898
gene id: 8078:LOC105928898
uniprot id: A0A3Q2Q4F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space

8078:rplp1
gene id: 8078:rplp1
uniprot id: A0A3Q2P606
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

8078:LOC105916711
gene id: 8078:LOC105916711
uniprot id: B6ZN55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Mitochondrion inner membrane

8078:ubp1
gene id: 8078:ubp1
uniprot id: A0A3Q2P4F7
uniprot id: A0A3Q2T0P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

8078:dmap1
gene id: 8078:dmap1
uniprot id: A0A146MQA1
names: Subcellular Location Annotation
messages: Nucleus

8078:ndufb7
gene id: 8078:ndufb7
uniprot id: A0A3Q2QL92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

8078:actn1
gene id: 8078:actn1
uniprot id: A0A146W2V1
uniprot id: A0A146W305
uniprot id: A0A3Q2NVM5
names: Similarity
messages: Belongs to the alpha-actinin family.

8078:ccnt1
gene id: 8078:ccnt1
uniprot id: A0A147B2F8
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin C subfamily.

8078:cx30.9
gene id: 8078:cx30.9
uniprot id: A0A3Q2TQ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8078:slc1a3a
gene id: 8078:slc1a3a
uniprot id: A0A3Q2UPX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8078:LOC105919028
gene id: 8078:LOC105919028
uniprot id: A0A3Q2TZ00
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homodimer; disulfide-linked.

8078:b2m
gene id: 8078:b2m
uniprot id: A0A3Q2PA34
names: Subcellular Location Annotation
messages: Secreted

8078:pfdn2
gene id: 8078:pfdn2
uniprot id: A0A3Q2Q164
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

8078:gdf9
gene id: 8078:gdf9
uniprot id: A0A3Q2PBM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

8078:edem3
gene id: 8078:edem3
uniprot id: A0A3Q2NPT0
uniprot id: A0A3Q2NPV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8078:ccnj
gene id: 8078:ccnj
uniprot id: A0A3Q2TR90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8078:LOC105926324
gene id: 8078:LOC105926324
uniprot id: A0A3Q2PHD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8078:LOC105933491
gene id: 8078:LOC105933491
uniprot id: A0A3Q2SX26
names: Similarity
messages: Belongs to the cytochrome b5 family.

8078:LOC105936996
gene id: 8078:LOC105936996
uniprot id: A0A3Q2Q569
uniprot id: A0A3Q2R2V3
names: Similarity
messages: Belongs to the serpin family.

8078:trappc2l
gene id: 8078:trappc2l
uniprot id: A0A3Q2PU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

8078:LOC105919742
gene id: 8078:LOC105919742
uniprot id: A0A3Q2P7D5
uniprot id: A0A3Q2QH74
names: Subcellular Location Annotation
messages: Cell junction
messages: Golgi stack
messages: Synapse
messages: cytoskeleton

8078:ldlra
gene id: 8078:ldlra
uniprot id: A0A3Q2QJ65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:ildr1b
gene id: 8078:ildr1b
uniprot id: A0A3Q2PHS9
uniprot id: A0A3Q2QP74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8078:copz2
gene id: 8078:copz2
uniprot id: A0A146N8B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

8078:LOC105933080
gene id: 8078:LOC105933080
uniprot id: A0A146ZXD6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8078:kcng3
gene id: 8078:kcng3
uniprot id: A0A3Q2QEK5
names: Subcellular Location Annotation
messages: Membrane

8078:LOC105936752
gene id: 8078:LOC105936752
uniprot id: A0A3Q2QGF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

8078:lamtor2
gene id: 8078:lamtor2
uniprot id: A0A3Q2NSS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8078:gnb1a
gene id: 8078:gnb1a
uniprot id: A0A3Q2PFV7
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8078:LOC105937312
gene id: 8078:LOC105937312
uniprot id: A0A3Q2NPT2
names: Similarity
messages: Belongs to the globin family.

8078:cpt2
gene id: 8078:cpt2
uniprot id: A0A3Q2PIZ1
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8078:LOC105932282
gene id: 8078:LOC105932282
uniprot id: A0A3Q2QBK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

8078:trhra
gene id: 8078:trhra
uniprot id: A0A3Q2QHB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

8078:lclat1
gene id: 8078:lclat1
uniprot id: A0A3Q2QXY1
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8078:pdcl
gene id: 8078:pdcl
uniprot id: B6SAG6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8078:gfap
gene id: 8078:gfap
uniprot id: A0A3Q2NMR8
names: Similarity
messages: Belongs to the intermediate filament family.

8078:mindy4
gene id: 8078:mindy4
uniprot id: A0A3Q2QDP4
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

8078:gng7
gene id: 8078:gng7
uniprot id: A0A3Q2QHA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8078:kcnab1b
gene id: 8078:kcnab1b
uniprot id: A0A3Q2QY70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8078:LOC105925254
gene id: 8078:LOC105925254
uniprot id: A0A3Q2QQD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

8078:LOC105924971
gene id: 8078:LOC105924971
uniprot id: A0A3Q2UB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

8078:cdipt
gene id: 8078:cdipt
uniprot id: A0A3Q2Q3Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

8078:dck
gene id: 8078:dck
uniprot id: A0A3Q2PWD0
names: Similarity
messages: Belongs to the DCK/DGK family.

8078:ercc5
gene id: 8078:ercc5
uniprot id: A0A3Q2UIB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

8078:nrg2a
gene id: 8078:nrg2a
uniprot id: A0A3Q2PM82
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

8078:LOC105922256
gene id: 8078:LOC105922256
uniprot id: A0A3Q2PUY4
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8078:jupa
gene id: 8078:jupa
uniprot id: A0A3Q2Q713
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: desmosome